Atoris lossis Rosuvastatin: dab tsi yog qhov sib txawv thiab qhov twg zoo dua rau xaiv

Peb cov neeg nyeem tau siv Aterol ua tiav kom qis cov roj (cholesterol). Pom qhov nrov ntawm cov khoom no, peb tau txiav txim siab muab nws rau koj kom txaus siab.

Ntau tus neeg muaj cov teeb meem kev noj qab haus huv uas cuam tshuam txog vascular mob. Yog li, koj yuav tsum paub dab tsi cov ntsiav tshuaj roj (cholesterol) muaj nyob thiab seb lawv ua haujlwm li cas.

Thaum tib neeg pom cov roj (cholesterol) hauv lawv cov ntshav, ntau tus neeg nug: "Cov tshuaj rau cov roj (cholesterol) puas ua haujlwm zoo lossis tsis tsim?" Nrog rau cov ntsiav tshuaj, kev noj haus thiab ua si lub cev yog qhov tseem ceeb. Yog li, nws yog qhov tseem ceeb kom paub tias hom tshuaj muaj roj uas txhaws roj tsawg? Yuav ua li cas lawv yuav tsum coj?

Cov cholesterol tsis zoo

Cov tshuaj tseem ceeb hauv tib neeg cov ntshav yog cov roj (cholesterol), uas muaj nyob hauv yuav luag txhua lub cell qog. Vitamin D thiab cov tshuaj tiv thaiv hormonal yog tsim los ntawm nws, thiab nws tseem ua rau tiv thaiv kab mob. Cov roj cholesterol ua rau txoj haujlwm zoo ntawm lub hlwb, daim siab, cov leeg thiab cov hlab ntaws. Txawm li cas los xij, los ntawm cov roj (cholesterol) siab, muaj kev phom sij vascular pathologies tshwm sim.

• tiv thaiv kom txhob tsub zuj zuj ntawm hydrocarbons,
• koom nrog kev tsim cov vascular hlwb,
• pab kev tsim cov kua tsib thiab cov tshuaj hormones tsim los ntawm cov qog adrenal,
• muab kev koom tes hauv cov metabolism,
• cais tawm cov hlab ntsha
• pab kom nqus cov vitamin D.

Ib qho enzyme yog tsim los ntawm daim siab mob hlwb, thiab cov protein hloov nws los ntawm ntshav. Raws li qhov no, lub ntsej muag saw, uas tom qab ntawd tig mus rau hauv lipoprotein cov lus ntawm cov khoom sib txawv.

Cov nyhuv ntawm lub cev yog nyob ntawm cov qauv ntawm cov khoom no. Yog tias qhov lipoproteins tsawg (LDL) tsawg, tam sim no ces cov quav hniav tawm rau hauv cov hlab, tom qab ntawd atherosclerosis tuaj yeem tshwm sim. Nrog siab impermeability (HDL), qhov hloov pauv ntawm cov roj (cholesterol) thiab kua tsib cov kua qaub yog tshwm sim, uas ua rau txo qis kev pheej hmoo ntawm atherosclerosis.

Txhawm rau txiav txim siab txog qib ntawm cov tshuaj no, ib qhov kev kuaj ntshav biochemical tau ua tiav. Cov cai ntawm kev ntsuas muaj qhov sib txawv ntawm tus txiv neej thiab poj niam, lub hnub nyoog ntawm tus neeg kuj cuam tshuam tus nqi. Hauv qhov muaj zog ib nrab, txhawb cov roj cholesterol feem ntau pom.

Ib qho kev nce siab ntawm cov khoom noj uas muaj tsawg kawg lipoproteins tom qab tsib caug xyoo tau sau tseg. Rau cov poj niam, qhov tshwm sim no yog xav thaum lub sij hawm lawm.

Vim li ntawd, cov kab mob loj pathological xws li mob ntshav ncig ntawm lub hlwb tuaj yeem tshwm sim, uas feem ntau ua rau myocardial infarction. Yog li, cov kws kho mob tau sau ntawv rau noj tshuaj kom pab txo cov rog.

Nrog kev mob plawv lossis mob hlab ntsha tawg, koj tsis tuaj yeem tso cai ua kom cov cholesterol nce siab. Txij li thaum kev rov ua dua ntawm kev txhim kho ntawm kev rov ua dua tshiab pathologies tuaj yeem nce ntxiv.

Dua li ntawm qhov tseeb tias cov rog hauv siab yog qhov txaus ntshai heev. Nws lub luag haujlwm hauv cov nyiaj nruab nrab yog loj heev, nws koom nrog txhua cov txheej txheem biochemical thiab xav tau rau lub neej ntawm lub cev. Yog li, tswj nws ib txwm yog qhov tseem ceeb, rau qhov no lawv siv tshuaj kho thiab ua lub neej kom raug.

Qhov ntsuas poob

Khoom noj khoom haus yog xaiv los ntawm kws kho mob, tab sis nws ua raws:

• txiav luam yeeb, haus luam yeeb,
• ntsev kom tsawg thiab cov zaub mov muaj roj,

• kev txwv cov tsiaj rog, nws yog qhov zoo dua rau hauv zaub
• zaub fiber ntau, cov carbohydrates complex thiab polyunsaturated acids yuav tsum muaj nyob hauv cov khoom noj.

Nws yog ib qho tsim nyog yuav tsum tau tso tseg cov khoom ntim muag thiab hnyuv ntxwm, ncuav qab zib, khoom qab zib, yob thiab muffins. Cov khoom noj muaj txiaj ntsig yuav tsis yog pab tshem tawm tus nqi siab xwb, tabsis tseem yuav txhim kho tus neeg lub neej kom zoo.

Nws tsim nyog pom tias 80% ntawm cov roj cholesterol yog tsim los hauv lub siab, thiab tshuav 20% ua rau noj zaub mov. Yog li, kev noj zaub mov kom raug thiab tsim nyog yuav pab tau nws li qub.

• poob phaus
• kev tawm dag zog txhua hnub
• taug qab cov calories

• muab mus rau qhov tsis zoo: haus dej cawv, haus luam yeeb,
• Zam kev ntxhov siab thiab poob siab.

Txo cov tshuaj no, koj tuaj yeem siv cov khoom lag luam raws li kev siv tshuaj ntsuab thiab kev siv tshuaj lom neeg biologically ntxiv. Omega-3 polyunsaturated fatty acids tiv thaiv plaques los ntawm kev nce thiab cov ntshav txhaws.

Muaj qee lub sijhawm thaum ua raws li kev noj zaub mov zoo, tso kev haus cawv thiab kev tawm dag zog ntev ntev tsis pab txo qis roj. Tom qab ntawd tus kws kho mob pom zoo kom haus cov tshuaj tshwj xeeb kom txo cov roj cholesterol.

Cov Hom Tshuaj

Niaj hnub no, muaj ntau cov tshuaj uas siv rau cov roj (cholesterol) siab. Lawv muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj thiab tsiav tshuaj. Tus kws kho mob, suav txog qhov xwm txheej ntawm tus neeg mob, xaiv txoj kev ua tau zoo tshaj plaws nrog kev mob tshwm sim tsawg kawg.

Cov tshuaj siv rau cov roj (cholesterol) hauv cov ntshav tau muab faib ua ntau hom.

1. Statins
2. Fibrates.
3. Cov tshuaj noj uas cuam tshuam nrog kev nqus ntawm lipoproteins tsawg ntom.
4. Nicotinic acid

Tsis muaj cov tshuaj zoo dua rau cov roj (cholesterol), hauv txhua hom tshuaj muaj ntau yam zoo thiab tsis zoo.

Cov txaj txaj yog suav tias feem ntau tshwm sim; lawv txo qis cov cholesterol. Lawv tsis ua mob rau daim siab, txawm tias muaj cov txiaj ntsig zoo ua rau nws. Txawm li cas los xij, yog tias ib tus neeg muaj kab mob siab rau siab, cov tshuaj no raug txwv tsis pub siv, vim tias muaj kev cuam tshuam loj heev (ua rau lub siab ua haujlwm) tuaj yeem tshwm sim.

Daim ntawv teev cov npe nrov statins:

1. Simvastatin - Zokor, Vasilip.
2. Atorvastatin - Liprimar, Atoris.
3. Rosuvastatin - Crestor, Acorta.

Qhov muaj zog tshaj plaws yog cov peev nyiaj ntawm pawg Atorvastatin thiab Rosuvastatin, nws raug nquahu kom haus lawv ib zaug ib hmos. Lawv tau xyaum tsis muaj kev mob tshwm sim, yog li lawv tuaj yeem kho txawm tias menyuam yaus.

Fibrate kev kho mob yog suav tias muaj tsawg. Lawv cuam tshuam rau cov lipid metabolism, tshwj xeeb hauv lipoproteins uas ntau ntau. Cov tshuaj no tau sau tseg hauv kev kawm. Fibrates tsis pub sib xyaw nrog statins. Lawv, zoo ib yam li txhua yam tshuaj, muaj cov kev mob tshwm sim, yog li thaum lawv tau muab tshuaj, cov yam ntxwv ntawm ib tus neeg raug suav nrog.

Cov tshuaj tiv thaiv kabmob (cholesterol) rau qhov ua kom tsis haum tshuaj (IAH) tsis tshua nrov, koj tuaj yeem yuav ib hom tshuaj (Ezetrol) hauv tsev muag tshuaj. Txo cov roj (cholesterol) yog ua tiav los ntawm kev txwv tsis pub nqus ntawm lipids los ntawm cov hnyuv. Cov tshuaj tsis muaj zog tshwm sim, thiab nws tuaj yeem ua ke nrog statins.

Nicotinic acid los yog niacin muab qhov txiaj ntsig zoo. Nws inhibits zus tau cov lipids. Txawm li cas los xij, nicotinic acid tsuas cuam tshuam cov roj ntsha, yog li tom qab qhov kawg ntawm chav kawm, microcirculation tau sau tseg. Raws li txoj cai, nrog kev tsis tu ncua ntawm cov nyiaj no, cov txiaj ntsig qis dua tshwm sim.

Tsis tas li, rau cov kev cai ntawm kev zom, ua ntu zus ntawm cov kua tsib kua qaub yuav tsum tau noj. Qhov ua tau zoo tshaj plaws yog cholestyramine thiab colestipol. Lawv zoo li pwm cov kua tsib kua qaub thiab thauj lawv mus rau txoj hauv kev raws. Nrog cov tsis muaj lawv hauv lub cev, cov roj (cholesterol) nce ntxiv. Txawm li cas los xij, lawv tau muab tshuaj tsawg dua, vim tias lawv muaj ntau yam tshwm sim.

Polysaturated fatty acids nce oxidation hauv cov ntshav, thiaj li txo qis lipid. Lawv tsis muaj kev mob tshwm sim, tab sis cov nyhuv ntawm lawv tsis tshwm sim tam sim ntawd, tab sis tom qab ntev ntev.

Cov tshuaj pabcuam txo qis triglycerides hauv daim siab thiab qis dua LDL. Qhov tshwm sim ntawm kev kho mob ntev dua, yog li lawv tau raug txiav txim siab ntxiv rau cov tshuaj loj. Piv txwv, yog tias muaj cov khoom noj me me cog rau hauv tib neeg cov zaub mov noj, ces noj cov tshuaj fiber ntau hauv lub cev yuav ua rau qhov luv no.

Qhov zoo tshaj plaws rau txo cov roj ntshav siab yog:

1. Omega Forte.
2. Tykveol.
3. Lipoic acid.
4. Flaxseed roj.

Thaum muab tshuaj rau cov roj (cholesterol), feem ntau yuav tsum ua tib zoo saib:

• poj niam txiv neej thiab hnub nyoog
• muaj cov mob ntev thiab mob plawv,
• cwj pwm tsis zoo thiab kev ua neej.

Yog li, muaj cov npe dav dav rau cov tshuaj noj rau cov cholesterol. Nws yog ib qho tseem ceeb kom xaiv txoj kev kho kom zoo, suav txog txhua tus yam ntxwv ntawm tus neeg mob, tsuas yog hauv qhov no, qhov kev txo qis yuav tau txais txiaj ntsig.

Tsuas yog tus kws kho mob tuaj yeem sau cov tshuaj kom tsim nyog thiab lwm cov lus qhia uas tsim nyog.

Txog kev tiv thaiv, cov kws kho mob qhia tom qab 20 xyoo (ob zaug ib xyoo caum) los ua kev soj ntsuam los txiav txim seb puas muaj roj cholesterol. Txij li thaum lub hnub nyoog nyob hauv tib neeg ua lub neej tsis ncaj ncees, nws muaj peev xwm nce ntxiv. Yog tias tus neeg mob muaj kev pheej hmoo, ces qhov ntsuas yuav tsum tau kuaj xyuas tsis tu ncua, tsawg kawg 1-2 zaug hauv ib xyoos.

Roj 11 mmol / l, yuav ua licas? Vim li cas nce thiab cov tsos mob txaus ntshai

1. Kev phom sij ntawm cov roj (cholesterol) siab
2. Ua rau muaj cov ntshav khov
3. Cov tsos mob txaus ntshai
4. Cov Tshuaj Kho Mob
5. Cholesterol yog qhov qub - 15 cov cai

Nrog kev nce siab hauv cov roj hauv cov ntshav siab, qhov kev pheej hmoo ntawm lub plawv nres thiab mob stroke nce ntau zaus. Yog tias cov roj (cholesterol) yog 11, yuav ua licas, yuav ua li cas sai rau qhov ntsuas no? Puas yog tshaj qhov tsis suav nrog txhais tau tias yog mob stroke tam sim lossis thaiv cov leeg ntshav?

Ntsig, qhov teeb meem yog daws tau yooj yim, tab sis kev kho yuav tsum tau pib tam sim ntawd.

Rosuvastatin

Rosuvastatin yog cov tshuaj niaj hnub los ntawm cov pab pawg neeg statins, txoj kev tshawb nrhiav uas txuas ntxiv mus txog niaj hnub no. Cov txheej txheem ntawm kev ua yog zoo ib yam li cov tshuab ntawm kev ua ntawm Atoris. Muaj nyob hauv daim ntawv ntawm cov ntsiav tshuaj hauv koob tshuaj 5 txog 40 mg. Qhov siab tshaj plaws muaj tshwm sim hauv 2 lub lis piam txij li hnub pib tswj hwm.

Cov lus qhia rau Rosuvastatin thiab Atoris zoo tib yam.

Cov tshuaj thaiv tsis raws nyob nrog kev siv tshuaj txhua hnub: txog li 30 mg lossis ntau dua 30 mg. Cov tshuaj tiv thaiv rau Rosuvastatin zoo ib yam rau Atoris, tab sis nrog ntxiv ntawm cov ntsiab lus tseem ceeb. Lub sijhawm teem ntawm rosuvastatin hauv kev noj tshuaj tsis ntau tshaj 30 mg yog txwv tsis pub nrog:

1. Mob raum tsis ua hauj lwm.
2. Kev siv txuas ntxiv ntawm cyclosporin immunosuppressant.
3. Qhaj ntawv tsis mus ua kev tswj kom tsis txhob muaj menyuam yaus tsis tu ncua rau cov pojniam thaum lub hnub nyoog yug menyuam.

Rau qhov noj tshuaj txhua hnub ntau dua 30 mg, cov kab mob hauv qab no contraindications muaj:

• Mob raum thiab mob raum tsis ua haujlwm.
• Txais tos Cyclosporine.
• Txais tos ntawm cov fibrates (Piv txwv, Fenofibrata).
• Cov tsis muaj txoj hau kev mus ib txhis hauv kev xeeb tub hauv cov poj niam lub sijhawm yug menyuam.
• Lub xub ntiag muaj cov kev tsis sib haum xeeb hauv kev kho statins yav dhau los.
• Kev Hypothyroidism
• Kev haus dej haus cawv ntau ntxiv.

Kev sib piv ntawm cov tshuaj: zoo sib xws thiab sib txawv

Cov tshuaj yog cov sib koom ua ke los ntawm ib pab pawg kws kho mob, zoo sib xws hauv cov txheej txheem ntawm kev ua thiab kev ntsuas.

Cov koob tshuaj yog xaiv raws li ib txoj ntsiab cai - raws li theem ntawm thawj cov cholesterol hauv cov ntshav. Txhua tus neeg mob yuav tsum hloov mus rau kev noj zaub mov kom rog tsawg. Siv tshuaj ib zaug ib hnub, tsis txhob koom nrog kev noj zaub mov, tab sis nruj me ntsis thaum tib lub sijhawm.

Cov tshuaj tiv thaiv tseem muaj qhov zoo sib xws, tab sis rau Rosuvastatin lawv muaj ntau qhov dav dua.

Cov kev mob tshwm sim tshwm sim ntau dua thiab tau hais tawm thaum noj Atoris. Tej zaum qhov no yog vim muaj qhov tseeb tias Rosuvastatin tam sim no tsis to taub tag nrho. Feem ntau cov kev mob tshwm sim rau Atoris yog:

• Tej leeg tsis muaj zog: mob taub hau, ua kom tsaug zog ntog pw tsaug zog.
• Mob plawv: mob hauv siab.
• Kab mob ntsws: hnoos qeev, mob caj pas, hnoos.
• Lub plab zom mov: kev mob plab, xeev siab, cem quav lossis zawv plab, flatulence.
• Osteoarticular system: kev sib koom thiab mob leeg, mob pob qij txha (mob caj dab).
• Kev ua xua nyob rau hauv daim ntawv ntawm daim tawv nqaij ua pob.

Teeb meem thaum noj Rosuvastatin tsis tshua hais tawm:

• Los ntawm cov kab mob hauv lub cev: mob taub hau, kiv taub hau.
• Kab mob ntsws: hnoos.
• Lub plab zom mov system: cem quav, xeev siab.
• Cov kab mob Osteoarticular: mob leeg.
• Tso zis hauv lub cev: qhov pom tshwm sim ntawm cov protein nyob hauv cov zis. Qhov siab dua ntawm cov koob tshuaj txhua hnub, cov qib protein ntau dua.
• Mob ntshav qab zib mellitus.

Nyias, nws yog qhov yuav tsum tau hais txog cov teeb meem kev mob tshwj xeeb muaj xws li:

• Txhawb lub siab ua haujlwm nce siab (ALT thiab AST).
• Kev puas tsuaj rau cov leeg pob txha caj qaum nrog kev txhim kho ntawm rhabdomyolysis nws thiaj li - cov leeg mob rhuav tshem thiab nce hauv qhov no, qhov enzyme CPK (creatine phosphokinase).

Cov kev mob no tsis yog nquag thiab tuaj yeem tiv thaiv! Txhua tus neeg mob niaj hnub kho nrog statins yog qhia kev tshawb biochemical ntawm cov ntshav txhaws ib zaug txhua 3 lub hlis los saib xyuas qib ntawm cov enzymes. Kev nce ntawm ALT thiab AST los ntawm 3 zaug lossis ntau dua, thiab CPK - los ntawm 5 zaug lossis ntau dua piv rau qhov raug cai sab saud yog qhov ntsuas pom tseeb rau kev tshem tawm cov tshuaj.

Cov theem ntawm cov kev ua ntawm cov tshuaj sib txawv. Rosuvastatin yog ob zaug ua haujlwm nquag Atoris ntawm tib lub sijhawm. Thiab cov txiaj ntsig sib npaug tuaj yeem tau los ntawm kev noj 20 mg ntawm Atoris lossis 10 mg ntawm Rosuvastatin. Vim li no max. cov nyhuv ntawm kev kho mob rau rosuvastatin tshwm sim ob zaug sai dua (los ntawm qhov kawg ntawm 2 lub lis piam) dua li rau Atoris (los ntawm qhov kawg ntawm 4 lub lis piam).

Qhov twg yog qhov zoo dua thiab nyob rau qhov xwm txheej twg?

Nrog myocardial infarction, Atoris ua tau zoo tshaj thiab muaj kev nyab xeeb. Nws txoj kev tswj hwm yog nqa tawm tom qab tswj kev tswj hwm tus mob rau kev tiv thaiv ntawm kev rov ua lub plawv nres.

Nws kuj nyab xeeb rau cov neeg mob ntshav qab zib.

Rosuvastatin tsawg dua yuav ua rau muaj kev nce ntxiv hauv daim siab, uas txhais tau tias nws yog qhov zoo rau cov neeg mob mob siab mob siab.

Hauv porphyria, tib qho statin uas tuaj yeem nqa yog rosuvastatin.

Tab sis nco ntsoov: koj tuaj yeem coj cov statins tsuas yog tom qab sab laj thiab kev kuaj mob los ntawm tus kws kho mob!

Kev phom sij ntawm cov roj (cholesterol) siab

Daim lipid uas ua rau hauv lub siab, qog adrenal thiab cov hnyuv yog cov roj cholesterol, ib yam khoom tsim nyog rau kev ua haujlwm ntawm lub hlwb. Tab sis, qhov ntau dhau ntawm cov khoom muaj roj zoo li no hauv cov ntshav ua rau nws cov tsub zuj zuj ntawm phab ntsa sab hauv ntawm cov hlab ntsha. Uas ua rau yus cov quav hniav.

Peb cov neeg nyeem tau siv Aterol ua tiav kom qis cov roj (cholesterol). Pom qhov nrov ntawm cov khoom no, peb tau txiav txim siab muab nws rau koj kom txaus siab.

Cov plahaum loj loj tuaj yeem thaiv tag nrho cov ntshav ntws los ntawm cov hlab ntsha - cov hlab ntshav hlab plawv, mob plawv lossis hlab ntsha tawg. Nov yog qib nce.

Cov tshuaj muaj dab tsi ua ke

Txhawm rau kom nkag siab qhov txawv yog dab tsi thiab yam tshuaj twg zoo dua - Rosuvastatin lossis Atorvastatin, qhov kev sib piv sib piv yog qhov tsim nyog. Ob qho tshuaj nyob rau hauv kev txiav txim siab yog cov neeg sawv cev ntawm kev ua haujlwm tshiab ntawm statins. Nws yog ib qho tsim nyog yuav tau xaiv ib ntawm lawv thiaj li, nrog rau cov txiaj ntsig kho kom zoo, nws muaj kev cuam tshuam tsawg heev.

Lub tshuab ntawm lawv cov kev txiav txim siab kwv yees li qhov qub, tab sis muaj qee qhov sib txawv. Yog tias koj nkag siab qhov sib txawv ntawm lawv, tom qab ntawd koj tuaj yeem kho qhov kev kho mob ntawm tus neeg mob tshwj xeeb, uas yuav txhim kho qhov kev soj ntsuam kom nws rov zoo li qub. Ib qho tshwm sim thoob plaws ntawm Rosuvastatin thiab Atorvastatin yog tias ob qho tshuaj muaj cov nyhuv ob - lawv txo qis ntawm qhov tsis zoo thiab nce cov ntsiab lus ntawm cov roj (cholesterol) zoo.

Kuj tseem pom zoo rau ob yam tshuaj no yog tias lawv:

• txhim kho cov kev mob ntawm sab hauv kab ntawm cov hlab ntsha nrog nws qhov tsis ua haujlwm,
• txhim kho cov ntshav txaus hauv cov hlab ntsha,
• cov txiaj ntsig zoo rau ntawm phab ntsa vascular.

Ob qhov tshuaj muaj kev qhia dav dav rau kev siv. Txij li thaum lawv koom nrog cov statins ntawm lub xeem tiam, lawv tuaj yeem raug cai tsis yog rau kev kho mob, tab sis kuj rau lawv txoj kev tiv thaiv, uas nyuaj nrog statins ntawm thawj thiab tiam thib ob vim muaj ntau yam phiv los ntawm lawv.

Yog li, cov tshuaj txiav txim siab pom zoo siv rau cov neeg mob uas muaj kev pheej hmoo ntawm kev mob plawv mob ntshav siab. Cov ntsiab lus ua rau qhov kev pheej hmoo no suav nrog:

• hnub nyoog 55 xyoos
• keeb kwm mob ntshav qab zib mellitus,
• haus luam yeeb,
• ntshav siab
• raws roj ntsha muaj kab mob siab tuaj yeem ua rau kom cov cholesterol,
• txo cov ntsiab lus ntawm cov lipoproteins ntau ntom hauv cov ntshav.

Atorvastatin thiab Rosuvastatin tsis tau raug tshuaj rau kev kho mob ntawm menyuam yaus thiab tub ntxhais hluas, thaum pub niam mis thiab cev xeeb tub, nyob rau theem siab mob siab. Lawv siv nrog ceev faj yog tias tus neeg mob tau haus dej cawv, muaj kev nquag rau myopathy, lossis muaj keeb kwm muaj mob raum tsis zoo.

Qhov siab tshaj plaws rau kev kho mob ntawm kev noj cov statins ntawm ib tiam tshiab tau tom qab 4 lub lis piam los ntawm kev pib ua haujlwm. Yog tias cov tshuaj yog noj los ntawm tus poj niam uas tau tshwj tseg kev muaj peev xwm ntawm kev ua me nyuam, ces nws raug pom zoo, nrog rau cov statins, txhawm rau saib xyuas kev tiv thaiv kom zoo dua.

Ob qhov tshuaj muaj tsawg heev ntawm kev phiv, yog li lawv tau txais tau zoo los ntawm cov neeg mob. Lawv tuaj yeem noj tau tsis hais txog kev noj zaub mov thiab tsis siv rau lub sijhawm ntawm ib hnub.

Dab tsi yog qhov txawv

Kev sib piv ntawm cov tshuaj Atorvastatin thiab Rosuvastatin qhia tias, txawm hais tias qee qhov zoo sib xws, lawv zwm rau statins ntawm ntau tiam neeg. Rosuvastatin yog qhov kev tsim kho tshiab, thiab Atorvastatin ua ntej nws. Qhov zoo ntawm cov tub ntxhais hluas tam sim no yog qhov ua tau kom txo tau qhov ntau npaum ntawm cov tshuaj, vim tias nws ua tau zoo heev.

Tsis zoo li Atorvastatin, 90% ntawm Rosuvastatin raug tawm hauv lub plab zom mov, thiab 5% los ntawm cov zis. Tsis tas li ntawd, yog tias peb sib piv cov tshuaj nrog lwm tus piv txwv ntawm kev txo qis roj kom tsawg, ces Atorvastatin yog me ntsis qis dua rau Rosuvastatin.

Thawj qhov txo qhov siab tshaj plaws los ntawm 54%, thiab lub thib ob - los ntawm 63%. Lawv kuj sib txawv hauv ib nrab-lub neej. Yog tias rau Atorvastatin lub sijhawm no siv sijhawm li 15 mus rau 30 teev, tom qab ntawv rau Rosuvastatin - 19 teev.

Cov tshuaj ntawm cov tub ntxhais hluas tam sim no muaj ntau dua bioavailability. Qhov no txhais tau hais tias nws zoo dua nqus tau los ntawm lub cev. Tab sis qhov sib txawv ntawm lawv tsis tseem ceeb: Atorvastatin - 12% thiab Rosuvastatin - 20%.

Dab tsi qhov txawv cov tshuaj no tsis tau yog kev daws mob solubility. Yog li, Rosuvastatin yog tshuaj hydrophilic, thiab Atorvastatin yog lipophilic. Qhov no txhais tau hais tias atorvastatin yog soluble hauv cov rog, thiab rosuvastatin nyob hauv dej. Yog tias koj yuav tsum xaiv ntawm Atoris thiab Rosuvastatin, tom qab ntawd koj yuav tsum nco ntsoov tias Atoris yog ib hom ntawm Atorvastatin, yog li qhov zoo sib xws thiab txawv yuav muaj kwv yees li qub.

Hais txog kev nyab xeeb, ob qho tshuaj nyob rau hauv kev txiav txim siab yuav kwv yees li qub. Tab sis, piv txwv, nrog hom ntshav qab zib hom 2, rosuvastatin yuav tsum yog qhov zoo tshaj, vim tias nws tsis tshua muaj txiaj ntsig ntawm cov khoom noj metabolism.

Yog tias peb piv cov tshuaj no ntawm tus nqi, ces feem ntau tus nqi Atorvastatin yog tus nqi qis dua tus nqi ntawm Rosuvastatin. Hauv qhov kev nkag siab no, qhov ntau npaum ntawm cov tshuaj thiab cov naj npawb ntawm cov ntsiav tshuaj hauv pob yog qhov tseem ceeb. Piv txwv li, 90 ntsiav tshuaj ntawm 20 mg ntawm Atorvastatin yuav raug nqi txog 800 rubles, thaum rau rau tib lub pob ntawm Rosuvastatin koj yuav tsum tau them ntau dua 1000 rubles.

Kev txiav txim los ntawm qhov ua tau zoo ntawm cov tshuaj no, kev coj ua qhia pom tias Rosuvastatin muaj cov lus hais tau zoo dua piv rau Atorvastatin. Lawv cov hauj lwm zoo dua, thiab muaj peev xwm muaj kev phiv yog tsawg dua li ntawm cov statins uas yog tiam thawj tiam, piv txwv, simvastatin.

Nta ntawm Atorvastatin

Atorvastatin zwm rau qeb ntawm statins ntawm peb tiam. Cov tshuaj muaj nyob hauv ntau qhov ntau - 10, 20, 40 thiab 80 mg. Lub chaw muag tshuaj nthuav tawm 2 yam ntawm cov tshuaj no - Lavxias (Atorvastatin) thiab Israeli ntau lawm (Atorvastatin-Teva). Cov tshuaj nquag ntawm atorvastatin yog atorvastatin calcium trihydrate.

Cov tshuaj txo cov tshuaj ntsiab ntawm cov lipoproteins uas tsis muaj nqi thiab tib lub sijhawm nce cov ntsiab lus ntawm lipoproteins ntau ntom. Kuj ua tau haujlwm zoo hauv tsev neeg thiab homozygous hypercholesterolemia. Qhov ua tau zoo ntawm cov tshuaj tshwm sim tom qab 2 lub lim tiam ntawm kev siv li niaj zaus. Tom qab 30 hnub, qhov ua tau zoo tshaj plaws ntawm cov tshuaj tiv thaiv kab mob siab tuaj yeem ua tiav, uas txuas ntxiv mus tag nrho lub sijhawm tshuaj kho.

Txoj kev noj tsawg dua Atorvastatin yuav tsum muab sib xyaw nrog kev noj haus. Raws li cov khoom noj muaj mob, tus neeg mob yuav tsum tau cais tawm ntawm cov khoom noj muaj roj, thiab cov tais diav ua los ntawm kib. Koj tuaj yeem haus cov ntsiav tshuaj tsis hais lub sijhawm noj mov. Qhov ntau npaum li cas yog xaiv tau ib tus zuj zus los ntawm tus kws kho mob mus kawm raws li cov txiaj ntsig ntawm lipid profile.

Qhov tshuaj thawj zaug yog 10 mg, thiab tom qab ntawd, yog tias tsim nyog, nws tuaj yeem nce ntxiv txog 80 mg rau ib hnub. Cov neeg mob uas mob raum lossis mob siab tsis txaus noj atorvastatin txhua lub sijhawm ntawm kev pib muab tshuaj. Cov ntsiab lus rau kev teem caij ntawm Atorvastatin yog cov kev kho mob nyuaj rau theem ntawm tag nrho cov roj (cholesterol) thiab LDL thiab kev nce hauv triglycerides.

Cov kev mob tshwm sim hauv qab no tej zaum yuav tshwm sim nrog kev siv Atorvastatin:

• kev ntxhov siab vim pw tsaug zog
• mob taub hau thiab kiv taub hau,
• anemia los yog thrombocytopenia,
• dyspeptic mob
• mob caj dab thiab myalgia,
• ua xua
• o tuaj
• do hau
• nce hws
• rhiab rwg mus rau lub teeb.

Atorvastatin tsis raug siv rau kev siv nrog kev ua si ntawm daim siab enzymes, lub raum tsis ua haujlwm, thaum cev xeeb tub thiab lactation, nrog ib tus neeg tsis kam ua rau cov tshuaj ntawm cov tshuaj, mob siab hnyav pathologies. Cov tshuaj tseem tau contraindicated rau hauv cov neeg mob qis dua 18 xyoo.

Cov lus qhia rau kev siv tshuaj

Ua ntej koj pib siv cov tshuaj Torvakard, koj yuav tsum kawm cov lus qhia rau kev siv tshuaj thiab sab laj nrog koj tus kws kho mob. Ua ntej yuav noj cov tshuaj, tus neeg mob yuav tsum tau npaj, rau qhov no ob peb hnub yuav tsum yauv tsum noj tshuaj tshwj xeeb, uas yuav tsum tau ua raws yav tom ntej thoob plaws hauv kev kho mob.

Qhov muab tshuaj thawj zaug tsis pub ntau tshaj 10 milligrams ib hnub ib zaug. Maj mam, cov tshuaj ntxiv tuaj yeem raug nce ntxiv txog 80 milligrams ib hnub twg. Kev noj tshuaj tsis nyob ntawm lub sijhawm, nws raug tso cai siv nws lub sijhawm thaum nruab hnub, ua ntej, thaum lossis tom qab noj mov.

Hauv qhov no, qhov muab cov tshuaj yuav tsis tuaj yeem kho. Txhawm rau txiav txim siab siv tshuaj ntau npaum li cas, koj yuav tsum kawm tus kws kho mob cov lus pov thawj thiab kuaj txhua ob lub lis piam rau cov qib lipids uas muaj nyob hauv ntshav ntshav. Raws li cov ntaub ntawv tau, qhov tsim nyog ntau yog muab tso ua ke.

Raws li tau sau tseg hauv cov lus qhia rau kev siv, cov txiaj ntsig zoo los ntawm kev siv tshuaj kho mob tuaj yeem pom ob lub lis piam tom qab pib siv tshuaj yeeb.

Tom qab li ib hlis, qhov kev kho mob ua kom tiav nws cov txiaj ntsig siab tshaj plaws thiab mob siab rau lub sijhawm ntev yog hais tias kev kho mob txuas ntxiv.

Dab tsi yog ib feem ntawm cov tshuaj?

Cov tshuaj Torvakard yog tsim nyob rau hauv daim ntawv dawb dawb lub qe ntsiav tshuaj, zaj duab xis-txheej. Ib qho hlwv muaj kaum ntsiav tshuaj, hauv ib pob muaj los ntawm peb mus rau cuaj lub hlwv, nyob ntawm seb lub twg. Qhov ntsuas mob dab tsi rau kev siv yog kws kho mob tau sau tseg los ntawm tus kws kho mob.

Qhov muaj pes tsawg leeg ntawm cov tshuaj Torvakard suav nrog:

• Tsis tshua muaj tshuaj hyprolose,
• microcrystalline cellulose,
• magnesium oxide
• lactose monohydrate,
• magnesium stearate,
• croscarmellose sodium,
• colloidal silicon dioxide.

Cov muaj pes tsawg leeg ntawm cov zaj duab xis membrane suav nrog hypromellose 2910/5, talc, titanium dioxide, macrogol 6000.

Cov yam ntxwv ntawm cov tshuaj

Nyob ntawm seb qhov mob ntau npaum li cas, tus kws kho mob txiav txim siab qhov taw qhia rau kev siv tshuaj Torvakard. Cov tshuaj muaj peev xwm ua tau zoo hauv cov hom kabmob hauv qab no:

1. Nrog kev nce hauv cov ntshav triglycerides,
2. Nrog dysbetalipoproteinemia,
3. Nrog hypercholesterolemia,
4. Nrog hyperlipidemia,
5. Hauv cov kab mob ntawm cov hlab plawv vim muaj kev txawv txav ntawm cov qib lipid.

Lub caij no, raws li tau qhia hauv cov lus qhia rau kev siv, cov tshuaj Torvacard tuaj yeem ua rau muaj kev mob tshwm sim, ntawm cov uas muaj lub plawv dhia ceev.

Kuj tseem muaj qee qhov tsis sib haum xeeb. txuam nrog kab mob ntawm qee yam kabmob hauv nruab nrog.

Txawm hais tias qhov tseeb hais tias kev qhia tau pom tias muaj txiaj ntsig zoo ntawm cov tshuaj, koj yuav tsum ua nws nrog ceev faj, ua tib zoo kawm cov ntaub ntawv ntawm kev siv tshuaj thiab sab laj nrog koj tus kws kho mob.

Cov kev mob tshwm sim tom qab no tuaj yeem tshwm sim thaum siv tshuaj:

• Nrog rau kev koom tes ntawm cov zais pa hauv nruab nrog cev, tinnitus, kev tawm ntshav ntawm ntshav hauv lub qhov muag, hnov ​​lus tsis zoo, hnov ​​tsw ntawm saj, ua pa tawm ntawm lub qhov txhab yuav tshwm sim.
• Thaum lub paj hlwb cuam tshuam, tus neeg mob yuav hnov ​​mob taub hau, kiv taub hau, thiab tus neeg mob hauv qee kis pib mob vim muaj insomnia thiab npau suav phem. Kev nyuaj siab kuj ua tau.
• Thaum raug rau cov kab mob plawv hauv cov neeg mob, qee kis, lub plawv dhia, mob hauv siab tshwm sim.
• Hauv cov kab mob genitourinary, tso zis tsis txaus, nephritis, cystitis tuaj yeem tsim kho, qhov chaw mos los ntshav tuaj yeem pib. Xws li cov teeb meem ntawm impotence thiab cuam tshuam ntawm ejaculation.
• Qee zaum ib qho tshuaj muaj peev xwm ua rau muaj kev tsis haum tshuaj nyob rau hauv daim ntawv ntawm daim tawv nqaij khaus, dermatitis, tawm pob, urticaria, o.
• Tus neeg mob yuav ua rau tawm hws ntau, txhim kho eczema, seborrhea, lossis lwm yam kab mob tsis zoo.
• Xws li lub cev ua rau lub cev ua kom quav, ua tsis taus pa, kub siab, tso quav tawm, xeev siab, ntuav, thiab lub qhov ncauj qhuav yog tau. Muaj qee kis tshwj xeeb, kab mob siab, mob plab, mob ncauj plab, mob plab kiav txhab thiab lwm yam tsis tsim nyog los ntawm kev siv cov tshuaj.
• Vim yog kev ua txhaum ntawm cov roj ntsha hauv lub cev, ua kom ntshav khov, mob plab zais, lossis lymphadenopathy tuaj yeem tshwm sim.
• Nws kuj tseem tuaj yeem ua kom lub cev kub, nce ntxiv.

Nws yog ib qho tseem ceeb ntawm kev tiv thaiv menyuam yaus kom nkag mus rau hauv cov tshuaj. Khaws cov tshuaj ntawm qhov kub ntawm 10 txog 30 degrees. Txee lub neej yog ob xyoos.

Tus nqi ntawm cov tshuaj Torvakard nyob rau hauv Russia yog 275 rubles rau ib pob ntawm 30 ntsiav tshuaj ntawm 10 milligrams.

Rau leej twg yog cov tshuaj contraindicated?

Torvacard yuav tsum tsis txhob siv rau daim siab mob, thaum cev xeeb tub lossis pub niam mis, menyuam yaus lossis thaum tiav hluas, muaj qee tus tsis kam txais qee yam ntawm cov tshuaj. Qhov tshwm sim tsis zoo ntawm Torvacard ntawm kev muaj peev xwm tsav lub tsheb tsis tau qhia tawm.

Yog li, muaj cov nram qab no contraindications:

1. daim siab mob siab lossis nce siab kev ua haujlwm ntawm transaminases hauv cov ntshav cov ntshav ntawm cov keeb kwm tsis paub,
2. hepatic qhov tsis muaj txhij txhua ntawm qhov mob hnyav A thiab B ntawm Kev Siv Me Nyuam Pugh,
3. muaj cov kab mob muaj keeb, xws li lactose intolerance, lactase deficiency lossis glucose-galactose malabsorption, vim tias cov tshuaj muaj lactose,
4. cev xeeb tub lub sijhawm
5. lactation lub sijhawm
6. koj yuav tsum tsis txhob noj cov tshuaj rau cov poj niam uas tsis siv hom kev tiv thaiv,
7. cov menyuam yaus thiab cov tub ntxhais hluas hnub nyoog qis dua 18 xyoo,

Txawm hais tias muaj tseeb tias nws muaj kev taw qhia rau kev siv, koj yuav tsum noj cov tshuaj nrog ceev faj hauv kev haus cawv ntev. Kev txiav txim siab ua haujlwm thiab endocrine, mob hnyav hnyav, mob hlab ntsha tawg, mob hlab ntsha hlwb, muaj kab mob ntawm cov pob txha pob txha, muaj kev raug mob loj thiab kev phais mob.

1. Txheeb qhov tseeb ntawm cov ntaub ntawv kuaj

Txhawm rau kom kuaj cov ntawv tsis tas li kom tsis txhob cuam tshuam, tsis txhob hnov ​​qab tias cov ntshav tau muab rau ntawm lub plab khoob, thiab koj yuav tsum noj lub sijhawm kawg 12 txog 13 teev ua ntej kuaj ntshav thiab tsis pub dhau sijhawm.

Cov cuab yeej siv niaj hnub kuaj tsis suav nrog qhov yuam kev 99.9%, tab sis qee zaus tsis tshua muaj yuam kev. Tshwj xeeb tshaj yog thaum muaj cov lej loj yog pom hauv cov neeg hluas.

Qee zaum kev kho mob nrog tshuaj ntsiav pib tam sim. Qhov no tshwm sim thaum tus neeg mob pheej hmoo:

• Nws muaj kub siab (mob ntau zaus).
• Kab mob rau lub plawv (statins yuav tau haus txhua yam hauv kuv lub neej).
• Lub hnub nyoog tshaj 75 xyoo.
• Cuam tshuam tsis zoo.
• Mob ntshav qab zib mellitus.
• Kev pham
• Haus Yeeb.

Tseem Ceeb: ua ntej pib siv tshuaj kho nrog statins, noj tshuaj ntsuam kom lub siab kuaj.

1. Kev tawm dag zog lub cev yuav pab koj kom noj qab haus huv

• Yog tias ib tus neeg tau koom nrog kev kawm hauv lub cev, nws cov lipids tsis nyob ntev rau hauv cov hlab thiab yog li ntawd tsis khom ntawm lawv cov phab ntsa. Kev khiav haujlwm yog pab tshwj xeeb rau txo cov roj (cholesterol).
• Lub cev ua haujlwm hauv cov huab cua ntshiab, taug kev hauv lub tiaj ua si, seev cev nce ntxiv cov leeg nqaij thiab cov suab siab ntsws. Lawv muab lub xeev muaj kev xyiv fab, uas yog muaj txiaj ntsig zoo rau lub cev.
• Ib teev kev taug kev hauv cov huab cua huv txo qhov kev tuag ntawm tus kab mob vascular los ntawm 50%.

Txo cov theem ntawm lipids, koj yuav tsum tau ua cov yeeb yam nram no:

• Poob phaus (rau kev rog).
• Txiav Luam Yeeb.
• Tsis txhob haus cawv ntau dhau. Nws raug tso cai kom haus 200 ml dej cawv liab (lossis 50 ml dej cawv muaj zog) ib hnub.
• Tsis txhob noj ntau dhau.
• Ntau li ntau tau hauv huab cua huv.

2. Hais "Tsis muaj!" Rau cov khoom lag luam:

• Txo koj kev txais roj ntau. Lossis them rau nws los ntawm kev txeeb cov ntses rog, roj zaub thiab haus cawv me ntsis. Koj tuaj yeem noj lard nrog qej, uas yuav pab tau siv cov lipids.
• Tsis txhob noj cov qhaub cij nrog butter.
• Tsis txhob noj muaj roj ntxhiab roj, qe, qaub cream. Ntxiv cov khoom noj taum pauv rau koj cov khoom noj. Lawv normalize cov metabolism hauv.
• Qhov sib npaug ntawm cov rog cov rog yuav tsum raug tswj. Yog tias koj noj cov roj “hlais” roj, ua kom nws qab nrog zaub. Txhawm rau ua qhov no, sib tov cov pob kws (paj noob hlis), kua taum thiab txiv roj roj hauv qhov sib luag. Hauv porridge, nplej zom, zaub nyoos, ntxiv cov khoom sib xyaw no.

ul

Cov khoom noj roj kom tsawg

Ua ntej, cov peev txheej ntawm cov rog txaus yuav tsum tau cais tawm ntawm cov zaub mov, thiab cov zaub mov uas muaj cov roj cholesterol tsawg yuav tsum tau noj:

• Txhua txhua hnub, sim noj cov zaub mov ntawm xiav, xim liab thiab xim paj yeeb (pomegranate, txaij, carrots, prunes, txiv kab ntxwv, txiv av).
• Cov khoom siv roj thiab taum (vim tias lawv muaj cov roj fiber ntau) cov rog tsawg. Ntxiv rau, lawv kuj tuaj yeem hloov cov nqaij liab, uas ua teeb meem rau cov hlab ntshav ntau.
• Txhua cov zaub ntsuab (spinach, dill, dos, zaub txhwb qaib, artichoke) yog cov nplua nuj nyob hauv kev noj haus fiber ntau thiab lutein, uas ua rau txo qis kev pheej hmoo ntawm cov kab mob plawv.
• Cov zaub qhwv dawb yog ib tus thawj coj ntawm cov zaub uas muaj cov roj cholesterol tsawg. Tsawg kawg, nws yuav tsum noj tsawg kawg 100 g ib hnub nyob rau hauv ib daim ntawv twg.
• Cov nplej thiab oatmeal yog nplua nuj hauv fiber ntau. Lawv siv yog pab rau tag nrho lub cev, thiab kom txo cov roj (cholesterol) hauv qhov tshwj xeeb.
• Seaweed, oily hiav txwv ntses (zoo dua hau) muaj cov txiaj ntsig zoo ntawm kev txo qis lipids.

Cov roj ua kom ntshav qis

Nrog kev pabcuam ntawm cov tshuaj ntsuab thiab cov khoom noj tshwj xeeb, koj tuaj yeem txhim kho koj txoj kev noj qab haus huv, tab sis cov tshuaj muaj roj ua kom tsawg dua yog qhov muaj zog ntxiv.

Cov tshuaj ua kom qis qis lipid suav nrog:

Ib pawg tshuaj uas muaj qhov txiaj ntsig zoo ntawm cov roj (cholesterol) siab:

Tom qab statins, fibrates yog cov tshuaj thib ob rau kev kho mob hypercholesterolemia. Lawv siv nrog ntau theem ntawm lipids hauv cov ntshav (ntau tshaj 4.6 mmol / l).

Niacin (nicotinic acid, vitamin PP)

Qhov no yog vitamin B complex. Txo cov qib lipid. Nws yog txhaj rau hauv ntau npaum li cas raws li kws kho mob tau sau. Niacin tuaj yeem ua rau ua xua, ua xua. Nicotinks suav nrog cov tshuaj xws li nyempan thiab nicolar.

Cov chav kawm nrov tshaj plaws ntawm cov tshuaj rau kev txo qis roj. Tam sim no siv cov tshuaj:

• Atorvastatin (atoris, lypimar, torvacard).
• Simvastatin (Zokor, Vasilip, thiab lwm yam)
• Rosuvastatin (roxer, akorta, rosucard, ntoo khaub lig).

Qhov ua tau zoo tshaj plaws yog rosuvastatin thiab atorvastatin. Nqa lawv thaum hmo ntuj, 1 sijhawm hauv ib hnub.

Kev siv cov tshuaj thaum cev xeeb tub

Txij li cov roj (cholesterol) thiab cov tshuaj tso tawm los ntawm cov roj (cholesterol) yog qhov tsim nyog rau kev loj hlob ntawm tus me nyuam hauv plab, cov tshuaj muaj qhov cuam tshuam thaum cev xeeb tub thiab thaum lactation.

Thaum noj cov tshuaj hauv thawj peb lub hlis thaum cev xeeb tub, yug me nyuam ntawm cov pob txha deformity yog ua tau. Vim li no, yog tias koj siv cov tshuaj ua ntej cev xeeb tub thaum lub caij xeeb tub, koj yuav tsum tso tseg txoj kev siv cov tshuaj no kiag li.

Yog tias koj yuav tsum tau noj cov tshuaj thaum pub niam mis, koj yuav tsum tso tseg txoj kev pub mis niam kom tsis txhob ua mob rau tus menyuam. Tsis tas li, thaum siv Torvacard, cov poj niam yuav tsum muaj kev tiv thaiv kom zoo.

Omega-3 Polyunsaturated Fatty Acids (PUFAs)

Pab pawg no suav nrog ntau yam khoom noj tshuaj thiab tshuaj ua kom nrov: nrov tshaj plaws yog:

Cov tshuaj no muaj kev nyab xeeb heev thiab muaj cov txiaj ntsig zoo ntawm lub siab nqaij. Hmoov tsis zoo, lawv cov kev ua tau zoo yog tsawg thiab lawv tau sau tseg tsuas yog ua ke nrog fibrates lossis statins.

Kev nce rau hauv cov ntshav siab tuaj yeem tshwm sim:

• Vim lub cev ua tsis tau haujlwm.
• Qhov tshwm sim yog kev noj haus tsis sib npaug.
• Quav ntxiv rau qhov tsis zoo.
• Kev tshuaj ntsuam genetic predisposition.

Qhov kawg hloov tsis tau, tab sis txhua tus lwm tus tuaj yeem kho tus kheej. Thiab yog tias cov qib ntshav hauv cov ntshav tau nce siab me ntsis, nws yuav yog qhov zoo los xaiv txoj kev nyab xeeb kom txo qis - kom txo cov roj (cholesterol) yam tsis muaj tshuaj (nrog kev pab ntawm tshuaj ntsuab, kev kawm txog lub cev thiab kev noj zaub mov noj).

Cov Cholesterol thiab statins, yog nws tsim nyog noj cov tshuaj

Nimesil nrog mob taub hau Ketanov kev qhia. Lawv ua raws los ntawm lub tshuab tseem ceeb ntawm nws cov kev txiav txim siab thiab cuam tshuam nrog cov nyhuv hypocholesterolemic. Cov tshuaj nyob rau hauv lub npe lag luam Atorvastatin tuaj yeem yuav ntau pheej yig dua - qhov no yog ib qho ntawm qhov zoo ntawm Atorvastatin dhau ntawm Atoris.

• Pharmacological action Kev siv tshuaj Hypolipidemic los ntawm pab pawg ntawm statins.
• Atoris yog yeeb tshuaj los ntawm cov pab pawg neeg ntawm statins, uas muaj lipid-txo cov nyhuv ntawm lipid rog feem ntau.
• Muab rau 4 mg ib hnub twg.
• Yog li no, yog tias koj tsis zoo siab rau qhov tshwm sim ntawm kev noj atorvastatin, qhov tsis txaus siab no yuav tsum tau yuav luag txhua zaus los ntawm cov tshuaj txuas ntxiv no, tshwj xeeb yog tias nws cov nqi yog rubles.

Atorvastatin tuaj yeem ua rau muaj kev tsis haum tshuaj, suav nrog khaus ntawm daim tawv nqaij, lub raj tshuaj ntsuas, dermatitis, bronchospasm, alopecia. Atorvastatin yog tshuaj nrog kws kho mob, yog li tom qab noj tshuaj, nws tsim cov tshuaj atorvastatin. Feem ntau cov feem ntau, qhov muaj cov tshuaj tau hloov kho, uas muaj cov nyhuv ntawm patenting lawv.

Tias Atorvastatin hauv Moscow tuaj yeem txo rau cov neeg ua haujlwm. Los yog nrog dej ntxiv, kuaj lossis tshuaj, 80 mg yog tso rau hauv atorvastatin-c3 lab ntawm qhov tseem ceeb. Cov lus teb yog rau mob plab hnyuv, lub taub hau thiab ci. Thaj muaj ntau cov tshuaj uas lawv qhov kev txiav txim siab sau txog kev kam rau ua kom zoo dua li cov cim hauv qhov ntau uas tseem tsis tau muaj sijhawm rau tus mob gallstone soj ntsuam lossis tag nrho ntawm microflora ntawm tus kab mob. Ib zaug ntxiv, qhov kev ceeb toom tau tsim los ua cov xovtooj nrov dua ntawm tus nqi kim thiab tam sim no atorvastatin-c3 sawv Liprimar, tsim los ntawm lub tuam txhab opaque Ili.

Cov tshuaj puas rov qab rau koj?

Dab tsi yog statins?

Statins yog ib pawg sib txawv ntawm cov lipid-txo qis (lipid-txo qis) cov tshuaj siv los kho hypercholesterolemia, i.e., cov theem siab ntxiv ntawm cov roj (XC, Chol) hauv cov ntshav, uas tsis tuaj yeem txo siv txoj kev tsis siv tshuaj: muaj kev noj qab nyob zoo, kev ua si thiab kev noj haus.

Ntxiv nrog rau cov nyhuv tseem ceeb, statins muaj lwm yam muaj txiaj ntsig zoo uas tiv thaiv kev txhim kho cov hlab plawv mob hnyav:

• tswj txoj kev loj hlob ntawm atherosclerotic plaques hauv qhov chaw ruaj khov,
• ntshav ntswg los ntawm kev txo cov platelet thiab erythrocyte kev sib sau ua ke,
• siv ceev xwmphem o cov endothelium thiab rov ua nws txoj haujlwm,
• kev tsim kho ntawm kev sib txuas ntawm nitric oxide, tsim nyog rau kev so ntawm cov hlab ntshav.

Feem ntau, cov tshuaj statins noj nrog qhov tseem ceeb tshaj tawm ntawm cov tso cai cov roj (cholesterol) los ntawm 6.5 mmol / l, txawm li cas los xij, yog tias tus neeg mob tau muaj kev ua rau muaj kev phom sij (cov caj ces ntawm dyslipidemia, atherosclerosis uas twb muaj lawm, lub plawv nres lossis mob ntsws keeb kwm), tom qab ntawd lawv raug kho nyob rau qis dua - txij li 5 8 hliol / L.

Kev sib xyaw thiab txoj ntsiab cai ntawm kev nqis tes ua

Cov tshuaj sib xyaw ua ke ntawm cov tshuaj Atorvastatin (Atorvastatin) thiab Rosuvastatin (Rosuvastatin) suav nrog cov khoom siv hluavtaws los ntawm cov cim tiam tom ntej hauv daim ntawv ntawm cov ntsev calcium - atorvastatin calcium (III tiam) thiab calcium rosuvastatin (IV tiam) + ntu ntu, suav nrog cov mis ua haujlwm (lactose monohydrate) )

Lub tshuab ntawm kev ua ntawm ob qho tshuaj yog tswj kom muaj qhov tseem ceeb enzyme ua lub luag haujlwm rau cov roj (cholesterol): los ntawm kev txwv (tiv thaiv) cov tshuaj tua kab mob HMG-KoA reductase (HMG-CoA reductase) hauv lub siab, lawv txo cov khoom tsim mevalonic acid, tus txheej txheem ua ntej ntawm cov roj (endogenous) cov roj (cholesterol).

Ib qho ntxiv, statins txhawb kev tsim cov receptors lub luag haujlwm rau kev thauj cov lipoproteins tsawg (LDL, LDL), tshwj xeeb tshaj yog tsis tshua muaj qis (VLDL, VLDL) thiab triglycerides (TG, TG) rov qab ua rau lub siab ua rau pov tseg, uas ua rau txo qis "tsis zoo" cov roj cholesterol feem ntau. nyob rau hauv cov ntshav dej.

Qhov peculiarity ntawm cov cim kev tsim tawm tshiab yog tias lawv tsis cuam tshuam rau cov metabolism hauv cov metabolism, i.e., Atorvastatin thiab Rosuvastatin tsuas yog nce me ntsis ntxiv cov piam thaj hauv siab, uas tso cai rau cov neeg uas tsis muaj insulin-tiv thaiv hom mob ntshav qab zib hom II coj lawv.

Sab sij huam Cov Lus Sib Piv

Yog tias koj cia siab rau kev kho mob thiab kev tshuaj xyuas ntawm cov neeg mob noj statins ntev, thaum siv cov koob tshuaj loj ntawm ob yam tshuaj muaj sia ntawm ob tiam III thiab IV tiam, feem ntau tsis tshua muaj tshwm sim (txog 3%), kev phiv los ntawm qhov txawv txav ntawm qee qhov kab mob hauv lub cev tuaj yeem pom.

Kev sib piv ntawm cov "kev mob tshwm sim" ntawm Atorvastatin thiab Rosuvastatin (cov lus):

Cov tshuaj zoo tshaj plaws ntawm koob thib 3 thiab 4 tiam

Ntawm kev lag luam kws tshuaj, statins ntawm III thiab IV tiam yog sawv cev los ntawm cov tshuaj qub - Liprimar (atorvastatin) thiab Krestor (rosuvastatin), thiab cov ntawv luam zoo sib xws, qhov sib. cov generics uas tau ua los ntawm tib cov tshuaj muaj yees, tab sis nyob rau hauv lub npe txawv (INN):

• atorvastatin - Tulip, Atomax, Liptonorm, Torvakard, Atoris, Atorvastatin,
• rosuvastatin - Roxer, Rosucard, Mertenil, Rosulip, Lipoprime, Rosart.

Qhov kev ua ntawm cov generics yog yuav luag zoo tib yam rau qhov qub, yog li ib tus neeg muaj cai xaiv cov analogue no nws tus kheej, raws tus kheej nyiam.

Nws yog ib qho tseem ceeb kom nkag siab tias txawm tias qhov tseeb tias Atorvastatin thiab Rosuvastatin tsis zoo li qub, lawv kev nkag mus yuav tsum tau muab coj los sib npaug: ua tib zoo tshuaj xyuas lub xeev ntawm kev noj qab haus huv ntawm lub siab thiab ob lub raum, yav tas los thiab yav tom ntej, zoo li nruj soj ntsuam kev kho mob uas tus kws kho mob tau noj, thiab kev siv lub cev.

Koj puas tseem xav tias kev tshem tawm cov ntshav siab yog tsis yooj yim sua?

Kev txiav txim los ntawm qhov tseeb tias koj tau nyeem cov kab no tam sim no - teeb meem ntawm cov roj cholesterol siab tuaj yeem ua rau koj xav tau ntev ntev. Tab sis cov no tsis yog tso dag txhua: cov kev hloov pauv tau cuam tshuam loj heev ntawm cov ntshav ncig thiab, yog tias tsis ua raws li, tuaj yeem ua rau qhov tshwm sim tu siab tshaj plaws.

Tab sis nws yog ib qho tseem ceeb kom nkag siab tias nws yog qhov tsim nyog los kho tsis yog qhov tshwm sim hauv daim ntawv ntawm lub siab lossis tsis nco, tab sis qhov ua rau. Tej zaum koj yuav tsum paub koj tus kheej nrog txhua cov cuab yeej ntawm kev ua lag luam, thiab tsis yog qhia tawm xwb? Qhov tseeb tiag, feem ntau, thaum siv tshuaj lom neeg npaj nrog kev phiv, cov txiaj ntsig tau txais uas yog nrov npe hu ua "ib qho kev kho mob, lwm tus ceg tawv". Hauv ib ntawm nws cov kev pabcuam, Elena Malysheva tau chwv txog cov ncauj lus siab thiab hais txog cov kev kho mob uas ua los ntawm cov khoom siv cog ib puag ncig ...

Ua rau muaj cov ntshav khov

Kev ua raws li kev noj zaub mov tsim nyog tsis tuaj yeem lees tias cov roj cholesterol tsis nce ntxiv, vim tsuas yog nees nkaum-tsib feem pua ​​ntawm lipid nkag mus rau hauv lub cev nrog cov khoom noj. Qhov seem 75 feem pua ​​yog tsim tawm los ntawm cov khoom hauv nruab nrog cev.

Lub hauv paus cev lub luag haujlwm rau kev tsim cov roj ntsha yog cov roj ntsha. Yog li, kev ua txhaum cai nyob rau hauv daim siab ua rau ntau dua cov rog rog. Qhov lipid thiab cov qog adrenal ua cov khoom tsim, tab sis hauv ntau qhov ntau me.
Nws puas tuaj yeem xav txog tias kev noj zaub mov kom zoo tsis cuam tshuam rau cov roj cholesterol hauv cov ntshav txhua lub sijhawm, tab sis nws yog qhov tsim nyog los kho daim siab? Qhov no tsis muaj tseeb nkaus.

Qhov laj thawj thib ob uas ua rau muaj kev nce ntxiv yog maj mam tshem tawm cov lipid tawm hauv lub cev. Yog tias koj noj zaub mov ntau nyob rau hauv cov roj ntsha uas nyuaj rau yaj hauv lub plab thiab cov hnyuv txhua hnub, lub cev tsuas tuaj yeem tiv tsis taus nrog lub nra thiab tsis tswj kom ua tiav cov calories. Thaum kawg - roj 11, thiab cov lus nug yuav ua dab tsi?

Xaus - rau qib ib qho ntawm cov roj cholesterol, koj xav tau peb yam kev mob - kev noj zaub mov kom zoo, kev tawm dag zog thiab lub siab kom tsis muaj mob.

Muaj ntau lub laj thawj uas ua rau pom cov quav ntawm phab ntsa ntawm cov hlab ntsha:

• Ib txoj kev ua neej nyob so tom tsev thiab hauv tsev,
• Kev haus luam yeeb pab txo qis elasticity ntawm phab ntsa ntawm cov hlab ntsha, ua - cov teeb meem ntawm cov ntshav ncig thiab txhaws ntawm cov hlab ntshav,
• Kev haus dej cawv ntau hauv qhov ntau thiab tsis tu ncua kuj ua rau muaj qhov hloov pauv hauv cov roj (cholesterol) ntau ntxiv - poob qis lossis nce siab,
• Kev sib raug zoo ncaj qha tau pom ntawm kev rog ntawm qee qib thiab lipid.

Saib xyuas tag nrho cov saum toj no, peb xaus lus tias txoj kev ua neej tsis ncaj ncees coj mus rau cov teeb meem ntawm cov hlab plawv thiab lub plawv mob, kev ua cov plaques ceev ceev.

Tus nab npawb ntawm tus kab mob mus ntev thiab mob kuj ua rau muaj kev nce siab hauv cov cholesterol:

1. Mob ntshav qab zib mellitus
2. Lub qog teeb meem, hormonal tsis txaus,
3. Tsis hlauv
4. Kab mob siab.

Nrog kom cov roj (cholesterol) nce siab, koj yuav tsum tau mus kuaj mob tag nrho, vim tias qhov no yuav yog thawj cov cim qhia ntawm kev mob hnyav. Roj 11 yog cov tuag taus yog tias koj tsis quav ntsej txog tus lej siab no.

Cov tsos mob txaus ntshai

Yuav kom paub dab tsi ntawm cov roj cholesterol hauv cov ntshav tsuas yog ua tau los ntawm txoj kev kuaj (ntsuas ntshav dav dav). Cov tsos mob tsuas yog tshwm sim thaum ua cov quav hniav xwb twb tau ua rau txoj kev loj hlob ntawm atherosclerosis.

Cov tsos mob ntawm vascular atherosclerosis:

• Kev sib tawg ntawm phab ntsa ntawm cov hlab ntsha thiab qhov tsim ntawm cov ntshav txhaws, uas tuaj yeem ua rau mob stroke,
• Angina pectoris,
• Torn, quav hniav thaiv txoj hlab ntshav, ua rau mob thrombosis,
• Txij li cov ntshav ntws qeeb qeeb, muaj qhov tsis muaj zog thiab mob ntawm txhais ceg,
• Cov voj voos tsis zoo ua rau daj pom ncig lub qhov muag.

Cov Roj Choj 11, yuav ua licas? Ua ntej tshaj plaws, tsis txhob ntshai, tab sis tam sim ntawd sab laj nrog cov kws kho mob uas yuav sau ib daim ntawv tshuaj ntsuam xyuas tag nrho kom pom qhov ua rau cov roj (cholesterol) nce ntxiv.

Cov Tshuaj Kho Mob

Nws yog ua tau sai sai txo cov phom sij ntawm lipids nrog cov qauv kho mob, tshwj xeeb. Yog tias qhov ntsuas yog 11 lossis siab dua, ntawm tus nqi ntawm 3.6 txog 7.8 mmol / L, qhov ntuj tso ua ke ntawm lipids yuav tsum tau kho.

Txhua yam tshuaj los txo cov roj (cholesterol) yog ua rau cov roj ntsha hauv lub cev ua haujlwm, tsuas yog cov rog. Cov tshuaj tseem ceeb ntawm cov tshuaj no yog fenofibrate, simvastatin, rosuvastatin lossis atorvastatin.

Rau cov pab pawg ntawm cov tshuaj uas ua kom cov rog metabolism tsis xws li - Atomax, Simvor, Akorta, Ariescore.

Cholesterol yog qhov qub - 15 cov cai

Ua raws li cov kev cai yooj yim no, yuav tsis muaj ib lo lus nug - cov roj cholesterol 11, yuav ua li cas:

• Peb noj me ntsis, tab sis ntau zaus. Ib qho kev pabcuam ntawm cov zaub mov yuav tsum haum rau hauv lub xib teg ntawm koj txhais tes,
• Qhov kom zoo dua hauv kev noj haus yog muab rau cov txiv hmab txiv ntoo, txiv ntoo, ntses,
• Peb cais tawm cov rog hnyav, nyiam dua tsis qab - txiv ntseej roj, txiv ntseej, nqaij nruab deg,
• Peb cais tawm cov teeb meem carbohydrates, peb tawm hauv cov khoom noj uas muaj txiaj ntsig - cereals thiab mov, cereals, legumes,
• Roj ntses (Omega 3) - atherosclerosis yeej,
• Peb pib hnub nrog porridge
• Ntau txiv ntoo ntxiv, qab qab thiab txawv,
• Kev noj qab haus huv tau nyob ntawm no. Taug kev yuav tsum muaj tsawg kawg 30 feeb ib hnub, qhov ntau yuav zoo dua
• Peb tsuas yog noj mov tom tsev, peb tsis suav nrog cov zaub mov yoo mov tag,
• Txo kev haus kas fes rau 1 khob ib hnub,
• Tshaj dua cov khoom noj tshiab, ntuj tsim, tsis muaj tshuaj,
• Hnav sov, thaum mob khaub thuas, hlab ntshav muaj kev ntxhov siab loj,
• Lub suab zoo pw tsaug zog yog tus yuam sij rau qhov tsis muaj cov quav hniav,
• Saib qhov hnyav
• Ib zaug txhua rau lub hlis, kuaj xyuas cov ntshav lipid tsis txaus ntseeg.

Cov roj (cholesterol) 11 yog qhov siab tshaj yog tias koj tsis quav ntsej lub cev lub cim rau kev pab thiab txuas ntxiv ua lub neej muaj kev lom zem tab sis tsis zoo.

Kev taw qhia thiab contraindications

Atoris yog ib qho khoom siv uas txo cov kev kub siab ntawm cov teeb meem roj thiab plaques hauv qhov loj me, ua kom qeeb ntawm kev txhim kho atherosclerosis.

Lub hauv paus ua haujlwm tseem ceeb yog atorvastatin. Thawj cov tshuaj ntawm atorvastatin yog Liprimar, thiab Atoris yog ib qho tshuaj zoo ib yam, tab sis pheej yig dua nyob rau hauv nqe lus.

Atoris yog qhov muaj feem rau kev mob siab rau ntshav siab, muaj kev pheej hmoo siab ntawm kev tsim kab mob ntawm cov hlab plawv. Ua tsaug rau nws qhov kev txiav txim, cov kev pheej hmoo ntawm cov ntshav txhaws tsawg kawg.

Kev taw qhia rau kev siv:

• Cov rog hauv cov neeg laus, cov menyuam yaus tom qab 10 xyoo.
• Kev tiv thaiv lub plawv nres.
• Kev Tiv Thaiv Mob stroke
• Kev tiv thaiv kab mob ntawm lub plawv thiab cov hlab ntsha.
• Tawg siab
• Mob ntshav qab zib mellitus.
• Lub sijhawm rov qab los tom qab kev phais mob ntawm cov kab mob plawv.

Cov tshuaj tsis cuam tshuam zoo nrog lwm cov tshuaj. Kev siv cov statins ua ke nrog lwm hom tshuaj tuaj yeem ua rau muaj kev phiv loj heev hauv daim ntawv ua kom lub siab thiab lub raum tsis ua haujlwm. Qhov no yog qhov tseeb tshwj xeeb ntawm cov tshuaj tua kab mob, tshuaj rau cov kab mob fungus, tawm tsam kub siab, tsis tuaj yeem, thiab cov tshuaj uas ntxiv dag zog rau kev tiv thaiv kab mob.Ua ntej noj cov tshuaj, koj yuav tsum tau sib tham txog qhov no nrog tus kws tshaj lij.

Nws yog txwv tsis pub siv cov tshuaj kho mob rau daim siab mob siab, ib leeg nkag rau hauv cov tshuaj tseem ceeb lossis tshuaj pabcuam, nrog kev ceevfaj: nrog kev haus dej cawv, endocrine system cuam tshuam, mob ntshav qab zib, kab mob.

Rosuvastatin yog tus neeg saib xyuas lipid-qis, uas tau sau tseg yog tias lwm txoj hauv kev kho tsis ua haujlwm. Nws kuj tseem raug kho rau qee yam kev mob ntxiv. Nco ntsoov siv cov tshuaj no ua ke nrog cov khoom noj muaj haus.

Pom zoo rau kev siv nrog:

1. Hypercholesterolemia ntawm txhua yam.
2. Kev tiv thaiv kab mob ntawm cov kab mob plawv.

Nws tseem nquag tau sau tseg rau homozygous tsev neeg hom hypercholesterolemia. Ua ntej noj cov tshuaj, tus neeg mob yuav tsum hloov mus rau qhov tshwj xeeb noj rau cov roj (cholesterol). Qhov no yuav pab txhawb kev kho mob, nws yuav tsum raug rau lub sijhawm ntev, zoo dua li txawm tias tom qab kho tas.

Tsis tas li, cov tshuaj muaj ntau tus lej sib kis:

• ib tug neeg intolerance rau tshuaj,
• ua mob rau daim siab
• lub sijhawm thaum xeeb menyuam thiab pub niam mis,
• nyob rau hauv cov ntaub ntawv ntawm lactose intolerance,
• lub raum tsis ua hauj lwm zoo,
• cov me nyuam muaj hnub nyoog

Contraindication los siv yog kev kho mob ib txhij siv cyclosporine.

Cov lus qhia rau kev siv tshuaj

Txhua yam ntawm cov tshuaj muaj nws tus kheej cov lus qhia ruaj khov rau kev siv.

Atoris yog muaj nyob hauv ntsiav tshuaj daim ntawv. Cov chav kawm ntawm kev kho mob pib, feem ntau nrog tshuaj noj ntawm 10 milligrams ib hnub. Hauv ib lub hlis, cov naj npawb ntawm cov ntsiav tshuaj tuaj yeem nce ntxiv kom ua tiav cov nyhuv. Qhov siab tshaj plaws yog 80 milligrams ib hnub.

Rau txhua pab pawg hnub nyoog, noj ntau npaum li cas, nws yog qhov tshwj xeeb tshaj yog yuav tsum tau ua tib zoo saib xyuas cov lej ntawm cov neeg laus, poj niam thaum lub sijhawm lub cev ntas ntshav. Ntxiv nrog rau qhov pom tseeb zoo, cov tshuaj muaj qee qhov kev mob tshwm sim.

Nws tau sau tseg tias feem ntau noj tshuaj Atoris ua rau mob nqaij, tsis mob plab, mob taub hau, nkees, ua rau me ntsis ntawm qhov tsis nco thiab kev xav. Dua li ntawm qhov no, cov ntsiav tshuaj ua tau zoo dua li muaj kev phom sij, thiab koj yuav tsum tso tseg lawv txoj kev noj haus yog tias muaj kev cuam tshuam tsis yooj yim rau kev tiv thaiv.

Tsis pom muaj kev noj tshuaj rau kev noj tshuaj ntau dhau.

Kev noj tshuaj, koj yuav tsum ua raws li kev noj zaub mov tshwj xeeb, ua lub neej nquag, nws yuav tsum koom kev tawm dag zog lub cev. Yog tias tus neeg mob muaj teeb meem nrog qhov hnyav, koj yuav tsum poob phaus. Txoj kev kho yuav zoo dua yog tias ib tus neeg ua lub neej zoo.

Yog hais tias tus neeg mob txhawj xeeb txog cov leeg mob thiab qhov tsis muaj zog txaus, koj yuav tsum sab laj nrog tus kws kho mob tshwj xeeb. Thaum kho, koj yuav tsum tswj hwm kev ua haujlwm ntawm lub siab thiab lub raum, yog li ntawm 6 thiab 12 lub lis piam yuav tsum tau kuaj xyuas.

Nws yuav tsum nco ntsoov tias cov tshuaj muaj peev xwm nce cov ntshav qabzib hauv cov ntshav qab zib. Khaws cov tshuaj cia kom deb ntawm cov menyuam yaus, hauv qhov chaw tsaus, txias. Tus nqi ntawm cov tshuaj hauv Lavxias yog los ntawm 357 rubles

Rosuvastatin muaj nyob hauv daim ntawv foos. Nws yuav tsum tau noj ntawm qhov ncauj, haus dej kom ntau. Nws yog ib qho tsim nyog yuav tsum pib kho nrog 10 milligrams ib hnub, tom qab ntawd, yog tias tsim nyog, koj tuaj yeem nce lub koob tshuaj. Hauv raum tsis ua haujlwm, qhov koob tshuaj yuav tsum raug txo los ntawm ib nrab thaum pib ntawm chav kawm ntawm txoj kev kho. Qhov siab tshaj plaws tuaj yeem pom tau twb dhau peb lub lis piam tom qab pib kho. Tsis tas li, cov tshuaj muaj phiv nyob rau hauv daim ntawv ntawm:

1. myalgia
2. mob hypertonicity
3. mob caj dab, mob ntsws asthma,
4. insomnia, kev nyuaj siab, mob ntsws,
5. nce siab, nce kev ntxhov siab,
6. rhinitis, angina pectoris, ua xua,
7. ntshav qab zib ntshav siab,
8. angioedema
9. mob ntshav qab zib mellitus, palpitations.

Tawv daj thiab tawv nqaij muaj tsawg heev. Txhawm rau kom tsis txhob muaj cov kev tsis zoo, koj yuav tsum koom tes nrog cov tshuaj nrog koj tus kws kho mob thiab siv kom zoo. Tus nqi ntawm cov tshuaj hauv Lavxias yog los ntawm 275 rubles.

Atoris lossis Rozuvastatin txiav txim siab: qhov twg zoo dua rau tus kws tshaj lij xwb, vim tias txhua tus tuaj yeem sib txawv hauv cov yam ntxwv, thiab muaj kev cuam tshuam rau tib neeg lub cev sib xws.

Lub ntsiab analogues ntawm tshuaj

Ob qho tshuaj muaj cov tshuaj zoo sib xws.

Cov tshuaj ntawm cov tshuaj no zoo ib yam rau hauv cov nyhuv, tab sis qee qhov pheej yig dua, nrog qee qhov sib txawv ntawm cov tshuaj.

Yog tias tsim nyog, lawv tuaj yeem hloov cov tshuaj tseem ceeb, tab sis kev hloov pauv yuav tsum pom zoo nrog kws kho mob. Ntau tus tuaj yeem raug coj ua lwm txoj hauv kev.

Cov kws tshwj xeeb suav nrog Atorvastatin, Roxer, Rosucard, Simvastatin, Vasilip, Cardiostatin, Lovastatin los hloov cov tshuaj Atoris.

Tus nqi rau cov tshuaj muaj ntau yam sib txawv. Ib txhia ntawm lawv muaj ntau pheej yig dua. Koj tuaj yeem yuav lawv yam tsis tas yuav tshuaj, ntawm txhua lub tsev muag tshuaj.

Rosuvastatin kuj muaj qhov hloov:

Txhua yam ntawm cov tshuaj tuaj yeem hloov chaw rau cov tshuaj, vim hais tias lub tshuab ntawm kev ua thiab cov khoom tseem ceeb yuav luag zoo ib yam. Nyob rau hauv txhua rooj plaub, tsuas yog tus kws kho mob tuaj yeem hloov cov tshuaj, raws li kev qhia dav dav txog kev noj qab haus huv thiab chav kawm ntawm tus kabmob.

Thaum siv statins, koj yuav tsum coj mus rau hauv lawv qhov kev cuam tshuam nrog lwm cov tshuaj thiab ceev faj txog kev tiv taus ntawm cov tshuaj.

Nws yuav tsum raug sau tseg tias statin noj tsuas yog ua ke nrog lwm txoj hauv kev kho hypercholesterolemia: kev ua kis las, noj zaub mov tshwj xeeb, thiab muab cov kev coj ua tsis zoo.

Cov tshuaj Rosuvastatin tau piav qhia hauv cov yeeb yaj kiab hauv tsab xov xwm no.

• Stabilizes qib qab zib kom ntev
• Rov kho cov tshuaj insulin pancreatic

Cov tshuaj ua haujlwm nrog lwm cov tshuaj li cas?

Yog tias tus neeg mob tau noj ib qho tshuaj twg, nws yuav tsum tau sab laj nrog tus kws kho mob kom paub seb cov tshuaj no ua tau li cas nrog tshuaj Torvakard. Qhov tseeb yog tias cov tshuaj no, thaum sib cuam tshuam nrog lwm cov tshuaj muaj txiaj ntsig, tuaj yeem hloov nws txoj haujlwm, uas yog qhov tseem ceeb kom paub.

• Cov tshuaj cuam tshuam txo qis qib ntawm cov tshuaj nquag hauv cov ntshav, yog tias koj ntxiv noj tshuaj tiv thaiv kab mob thiab tshuaj tiv thaiv kab mob uas muaj azole, cloromycin, erythromycin, fibrate lossis cyclosporine.
• Cov tshuaj yeeb dej caw tsawg dua los ntawm ib feem peb, yog tias koj siv cov tshuaj ua ke nrog cov magnesium thiab aluminium hydroxide.
• Ib lub hlis twg muaj ib qho kev txo qis hauv cov tshuaj nquag nrog kev noj ntxiv ntawm colestiproloma.
• Muaj peev xwm txo qis ntawm steroid endogenous cov tshuaj hormones thaum siv nrog cimetidine, spironolactone thiab ketoconazole.
• Thaum siv cov tshuaj tiv thaiv ntau ntxiv ntawm qhov ncauj, qhov nce ntxiv ntawm qhov kev xav ntawm ethinyl estradiol thiab norethindrone tshwm sim.
• Cov nyhuv tshwj xeeb yog tsis pom thaum noj cov tshuaj nrog cimetidine, warfarin thiab phenozone.
• Tsis tas li, qhov kev tawm tsam tsis zoo yog tsis pom thaum siv nrog estrogens thiab tshuaj tiv thaiv antihypertensive.

Xws li qhov tshwm sim ntawm kev fab tshuaj nrog lwm cov tshuaj, vim li no cov kws kho mob sab laj yog qhov tsim nyog.

Cov tshuaj muaj haujlwm zoo sib xws

Torvacard muaj cov tshuaj tiv thaiv ntau yam, uas suav nrog tib yam khoom muaj nqis lossis kev npaj uas ua rau muaj lub cev zoo sib xws. Nws yog ib qho tseem ceeb kom nkag siab tias, txawm hais tias muaj cov txiaj ntsig zoo sib xws, cov kab mob analogues tuaj yeem muaj qhov sib txawv ntawm lub cev.

Vim li no, ua ntej yuav hloov mus rau ib qho tshuaj tshiab tom qab siv Torvacard, koj yuav tsum sab laj tus kws kho mob kom paub seb nws puas tso cai rau siv lwm txoj hauv kev ntxiv.

Raws li cov tshuaj yeeb tshuaj caw, cov tshuaj yeeb tshuaj hauv qab no Torvacard hauv cov ntsiav tshuaj tuaj yeem xaiv:

Raws li cov teebmeem ntawm lub cev, cov lus qhia hauv qab no suav nrog:

Nyob rau hauv txhua rooj plaub, ua ntej koj pib siv analogues, koj yuav tsum ua tib zoo nyeem cov lus qhia rau kev siv, kawm txog kev phiv, kev sib raug zoo nrog lwm cov tshuaj, thiab contraindications. Tsuas yog tom qab ntawd nws tsim nyog txiav txim siab seb puas yuav hloov mus rau ib qho analogue lossis txuas ntxiv siv Torvacard.

nyuam qhuav haus dej cawv torvakard.cov tshuaj pab tau kuv zoo heev. Lawv tsis kim thiab ua haujlwm sai. tom qab 2 lub lim piam nws tau mus rov qab muab cov ntshav. cholesterol tiag ntog poob qis.

Torvacard - cov lus qhia rau kev siv, tshuaj xyuas, tshuaj yeeb yaj kiab thiab tso tawm cov qauv (10 mg, 20 mg thiab 40 mg ntsiav tshuaj) ntawm cov tshuaj statin kom txo cov roj (cholesterol) thiab tiv thaiv kab mob plawv hauv cov laus, menyuam yaus thiab cev xeeb tub

Hauv tsab xov xwm no, koj tuaj yeem nyeem cov lus qhia rau kev siv tshuaj Torvard. Kev tshuaj xyuas cov neeg tuaj saib lub tsev kawm ntawv - cov neeg tau txais kev pab ntawm cov tshuaj no, nrog rau kev xav ntawm cov kws kho mob tshwj xeeb txog kev siv Torvacard statin hauv lawv cov kev coj ua tau hais tawm. Qhov kev thov loj yog nquag ntxiv kev tshuaj xyuas koj ntawm cov tshuaj: cov tshuaj tau pab lossis tsis pab ua kom tshem tawm ntawm tus kabmob, muaj dab tsi tshwm sim thiab cov kev mob tshwm sim, tejzaum nws tsis tshaj tawm los ntawm tus tsim khoom hauv cov lus piav qhia. Cov cim ntawm Torvacard nyob rau hauv muaj cov qauv txheej txheem qauv. Siv los txo cov roj (cholesterol) thiab tiv thaiv cov kab mob plawv rau cov neeg laus, menyuam yaus, nrog rau lub sijhawm cev xeeb tub thiab lactation.

Torvacard yog qhov tshuaj tiv thaiv hypolipidemic los ntawm pab pawg ntawm statins. Xaiv cov kev sib tw inhibitor ntawm HMG-CoA reductase, ib qho enzyme uas hloov 3-hydroxy-3-methylglutaryl-coenzyme A rau mevalonic acid, uas yog ib qho ua ntej rau steroids, suav nrog cov roj (cholesterol). Hauv lub siab, cov roj triglycerides thiab cov roj (cholesterol) nyob rau hauv VLDL, nkag mus rau cov ntshav ntshav thiab raug thauj mus rau cov ntaub so ntswg. Los ntawm VLDL, LDL yog tsim thaum muaj kev cuam tshuam nrog LDL receptors. Atorvastatin (cov tshuaj tseem ceeb ntawm cov tshuaj Torvard) txo cov ntshav plasma cholesterol (Ch) thiab lipoproteins los ntawm kev tiv thaiv HMG-CoA reductase, muab cov roj cholesterol hauv lub siab thiab nce cov LDL receptors hauv lub siab rau ntawm lub ntsej muag ntawm tes, uas ua rau nce siab thiab catabolism ntawm LDL Cov.

Atorvastatin txo qhov tsim ntawm LDL, ua rau muaj qhov tshaj tawm thiab pheej ua ntxiv rau hauv cov dej num ntawm LDL receptors. Torvacard txo qis LDL ntau ntau hauv cov neeg mob homozygous tsev neeg hypercholesterolemia, uas feem ntau tsis txaus siab los kho nrog lwm tus neeg mob hypolipidemic.

Nws txo cov theem ntawm cov roj (cholesterol) tag nrho los ntawm 30-46%, LDL - los ntawm 41-61%, apolipoprotein B - los ntawm 34-50% thiab triglycerides - los ntawm 14-33%, ua rau muaj qhov nce ntawm HDL-C thiab apolipoprotein A. Dose-dependently txo qib ntawm LDL hauv cov neeg mob nrog homozygous cov kab mob siab hypercholesterolemia tiv taus kev kho mob nrog lwm cov tshuaj lipid.

Atorvastatin calcium + excipients.

Kev tshem tawm yog qhov siab. Khoom noj khoom haus me ntsis txo qhov nrawm thiab ncua sijhawm ntawm kev nqus ntawm cov tshuaj (los ntawm 25% thiab 9%, feem), tab sis qhov txo qis hauv LDL cov roj (cholesterol) zoo ib yam li cov kev siv atorvastatin tsis muaj zaub mov. Qhov kev nkag siab ntawm atorvastatin thaum thov thaum yav tsaus ntuj yog qis dua thaum sawv ntxov (kwv yees li 30%). Txoj kab sib txuas ntawm qhov txheeb ze ntawm cov neeg nqus ntawm cov tshuaj thiab cov koob tshuaj tau qhia tawm. Nws yog metabolized feem ntau hauv lub siab. Nws yog tawm hauv cov hnyuv nrog cov kua tsib tom qab mob hepatic thiab / lossis cov kab mob hnyav ntxiv (tsis yauv ua kom nkag mus rau hauv lub cev). Cov kev cuam tshuam tiv thaiv kev ua haujlwm tiv thaiv HMG-CoA reductase tau tshwj tseg los ntawm qhov muaj cov khoom siv tshuaj nquag. Tsawg dua 2% ntawm kev noj tshuaj hauv qhov ncauj yog txiav txim siab nyob rau hauv cov zis. Nws tsis yog nyob hauv tus kab mob hemodialysis.

• hauv kev sib xyaw nrog kev noj zaub mov kom txo tau cov theem siab ntawm tag nrho cov roj (cholesterol), roj cholesterol-LDL, apolipoprotein B thiab triglycerides thiab nce roj cholesterol-HDL rau cov neeg mob thawj hypercholesterolemia, heterozygous tsev neeg thiab tsis-tsev neeg hypercholesterolemia thiab sib xyaw (sib xyaw) hyperlipidemia (hom 2a thiab 2) ,
• hauv kev sib xyaw nrog kev noj zaub mov noj rau kev kho mob ntawm cov neeg mob uas tau txais txiaj ntsig ntshav ntau ntau (yam 4 raws li Fredrickson) thiab cov neeg mob dysbetalipoproteinemia (hom 3 raws li Fredrickson), hauv kev kho kev noj zaub mov tsis muaj txiaj ntsig,
• kom txo qis ntawm tag nrho cov roj (cholesterol) thiab LDL-C hauv cov neeg mob homozygous tsev neeg hypercholesterolemia, thaum kev noj zaub mov noj thiab lwm yam kev kho mob tsis muaj tshuaj tsis zoo txaus (raws li qhov txuas rau lipid-txo kev kho, suav nrog autohemotransfusion ntawm LDL-purified ntshav),
• cov kab mob ntawm cov hlab plawv (hauv cov neeg mob uas muaj kev pheej hmoo ntau ntxiv rau cov kab mob plawv - cov neeg laus dua 55 xyoos, haus luam yeeb, mob ntshav siab, ntshav qab zib mellitus, mob hlab ntsha hauv lub cev, mob hlab ntsha tawg, sab laug ventricular hypertrophy, protein / albuminuria, cov hlab ntshav hlab ntshav hauv cov neeg nyob ze ), suav nrog tawm tsam keeb kwm ntawm dyslipidemia - theem nrab prophylaxis nrog lub hom phiaj ntawm kev txo qis kev pheej hmoo tag nrho ntawm txoj kev tuag, myocardial infarction, mob stroke, rov pw hauv tsev kho mob rau angina pectoris thiab xav tau tus txheej txheem kho kom rov zoo siab.

10 mg, 20 mg thiab 40 mg zaj duab xis-ntsiav tshuaj.

Cov lus qhia rau kev siv thiab regimen

Ua ntej kev teem caij Torvacard, tus neeg mob yuav tsum qhia kev noj haus kom tsis txhob lipid-txo cov zaub mov, uas nws yuav tsum tau txuas ntxiv mus kom thoob rau txhua lub sijhawm ntawm kev kho.

Thawj koob tshuaj yog qhov nruab nrab ntawm 10 mg ib hnub ib zaug. Qhov kev txhaj tshuaj nws txawv ntawm 10 txog 80 mg ib hnub ib zaug. Cov tshuaj tuaj yeem noj tau txhua lub sijhawm ntawm ib hnub, tsis hais lub sijhawm noj mov. Cov koob tshuaj yog xaiv rau hauv kev txiav txim siab thawj theem ntawm LDL-C, lub hom phiaj ntawm txoj kev kho thiab cov txiaj ntsig ib leeg rau ib leeg. Thaum pib kho thiab / lossis thaum qhov nce ntxiv ntawm lub tshuaj Torvacard, nws yog qhov yuav tsum tau soj ntsuam cov ntshav lipid ntau ntau txhua 2-4 lub lis piam thiab kho qhov tshuaj raws li. Qhov tshuaj ntau tshaj txhua hnub yog 80 mg hauv 1 koob tshuaj.

Nyob rau hauv thawj hypercholesterolemia thiab sib xyaw hyperlipidemia, feem ntau, ib koob tshuaj 10 mg ntawm Torvacard ib hnub ib zaug yog txaus. Cov txiaj ntsig kho tau zoo pom tom qab 2 lub lis piam, raws li txoj cai, thiab cov txiaj ntsig kho siab kawg feem ntau pom tom qab 4 lub lis piam. Nrog kev kho mob ntev, cov nyhuv no mob tsawv.

• mob taub hau
• asthenia
• insomnia
• kiv taub hau
• tsaug zog
• npau suav phem
• amnesia
• kev nyuaj siab
• peripheral neuropathy
• ataxia
• paresthesia
• xeev siab, ntuav,
• cem quav lossis raws plab
• flatulence
• mob plab
• anorexia lossis qab los noj mov,
• myalgia
• arthralgia
• mob hlwb
• mob mob vwm
• rov qab mob
• cramps hauv plab nqaij nyuj ntawm ob txhais ceg,
• khaus tawv
• ua pob
• urticaria
• angioedema,
• anaphylactic kev poob siab,
• ua pob khaus khaus,
• polymorphic exudative erythema, suav nrog Stevens-Johnson mob
• tshuaj lom neeg mob hlwb (Lyell syndrome),
• hyperglycemia
• qog ntshav,
• mob hauv siab
• peripheral edema,
• impotence
• alopecia
• tinnitus
• hnyav
• malaise
• tsis muaj zog
• thrombocytopenia
• theem ob lub raum tsis ua haujlwm.

• cov kab mob nquag ua haujlwm lossis nce siab hauv kev ua haujlwm ntawm transaminases hauv cov ntshav cov ntshav (ntau dua 3 zaug piv nrog VGN) ntawm cov keeb kwm tsis paub,
• mob rau daim siab ua haujlwm (mob hnyav A thiab B ntawm Kev Siv Me Nyuam Pugh),
• cov kab mob muaj keeb, xws li lactose intolerance, lactase deficiency lossis glucose-galactose malabsorption (vim muaj lactose hauv tshuaj muaj pes tsawg leeg),
• cev xeeb tub
• kev pub mis
• Cov poj niam kev muaj me nyuam hnub nyoog uas tsis siv cov hau kev tsim nyog ntawm kev tswj kom tsis muaj menyuam,
• cov menyuam yaus thiab cov tub ntxhais hluas hnub nyoog qis dua 18 xyoo (qhov ua tau zoo thiab kev nyab xeeb tsis raug),
• ua kom lub cev tsis haum rau cov tshuaj ntawm cov tshuaj.

Cev xeeb tub thiab lactation

Torvacard yog contraindicated nyob rau hauv cev xeeb tub thiab lactation (pub niam mis).

Txij li cov roj (cholesterol) thiab cov tshuaj sib tov los ntawm cov roj (cholesterol) yog qhov tseem ceeb rau kev loj hlob ntawm tus me nyuam hauv plab, qhov kev pheej hmoo muaj peev xwm los tiv thaiv HMG-CoA reductase ntau dua li cov txiaj ntsig ntawm kev siv tshuaj thaum cev xeeb tub. Thaum siv lovastatin (ib qho inhibitor ntawm HMG-CoA reductase) nrog dextroamphetamine hauv thawj peb lub hlis thaum cev xeeb tub, yug menyuam ntawm cov pob txha deformation, mob pob txha-esophageal fistula, thiab anus atresia paub.Yog tias cev xeeb tub raug kuaj pom thaum kho nrog Torvacard, cov tshuaj yuav tsum tau txiav tawm tam sim ntawd, thiab cov neeg mob yuav tsum ceeb toom rau qhov muaj feem yuav ua rau muaj menyuam hauv plab.

Yog tias nws yuav tsum tau siv cov tshuaj thaum lactation, muab cov peev xwm muaj qhov tsis zoo hauv cov menyuam mos, qhov teeb meem ntawm kev txwv tsis pub niam mis rau menyuam yuav tsum raug kho.

Kev siv hauv cov poj niam ntawm lub hnub nyoog yug me nyuam yog ua tau tsuas yog siv tau txoj hauv kev tiv thaiv kom siv tau. Yuav tsum qhia rau tus neeg mob tias qhov muaj feem yuav muaj feem yuav kho tus me nyuam hauv plab.

Cov tshuaj yog contraindicated rau siv nyob rau hauv cov menyuam yaus thiab tub ntxhais hluas hnub nyoog qis dua 18 xyoo (kev ua hauj lwm zoo thiab kev nyab xeeb tsis tau tsim).

Ua ntej pib siv Torvacard txoj kev kho, nws yog ib qho tsim nyog los sim ua kom tau tswj hwm hypercholesterolemia los ntawm kev kho zaub mov kom txaus, ua kom lub cev muaj zog, poob phaus hauv cov neeg mob rog thiab kho lwm yam mob.

Kev siv HMG-CoA reductase inhibitors kom txo cov ntshav lipids tuaj yeem ua rau muaj kev hloov pauv hauv cov khoom siv biochemical uas muaj kev cuam tshuam ntawm daim siab ua haujlwm. Lub siab ua haujlwm yuav tsum tau saib xyuas ua ntej pib kho, 6 lub lis piam, 12 lub lis piam tom qab pib noj Torvacard thiab tom qab txhua qhov kev nce ntxiv, thiab tseem tsis tseg (piv txwv, txhua 6 lub hlis). Kev nce ntawm kev ua si ntawm hepatic enzymes hauv cov ntshav cov ntshav tuaj yeem pom thaum kho nrog Torvacard (feem ntau hauv thawj 3 lub hlis). Cov neeg mob uas muaj qhov nce ntawm transaminase yuav tsum tau saib xyuas kom txog thaum lub enzyme rov qab los rau hauv qub. Yog tias qhov tshwm sim ALT lossis AST yog ntau dua 3 zaug siab dua li VGN, nws raug nquahu kom txo qis ntawm Torvacard lossis nres kev kho mob.

Kev kho mob nrog Torvacard tej zaum yuav ua rau myopathy (mob nqaij thiab tsis muaj zog ua ke nrog kev nce hauv CPK kev ua si los ntawm ntau dua 10 zaug piv nrog VGN). Torvacard yuav ua rau muaj kev nce ntxiv ntawm cov ntshav dej ntau ntau, uas yuav tsum tau suav nrog qhov ntsuas qhov txawv ntawm lub hauv siab. Cov neeg mob yuav tsum tau ceeb toom tias lawv yuav tsum tau sab laj nrog kws kho mob sai sai yog tias tsis hnov ​​qhov mob lossis cov leeg tsis muaj zog, tshwj xeeb tshaj yog tias lawv nrog mob tshwm sim lossis kub taub hau. Txoj kev kho Torvard yuav tsum tsis ua mus ib ntus los sis txiav tsis ua tiav yog muaj cov tsos mob ntawm tus mob myopathy lossis qhov muaj feem yuav ua rau lub raum tsis ua haujlwm vim mob rhabdomyolysis (piv txwv li, mob hnyav, mob ntshav qis, phais ntshav qis, mob hnyav, mob tshwm sim, mob hnyav ntawm lub cev, endocrine thiab electrolyte cuam tshuam thiab mob chua leeg). )

Cuam tshuam rau kev muaj peev xwm tsav lub tsheb thiab ua haujlwm nrog kev ua haujlwm

Qhov tshwm sim tsis zoo ntawm Torvacard ntawm kev muaj peev xwm tsav tsheb thiab koom nrog lwm yam uas yuav tsum muaj kev kub siab thiab ceev ntawm lub hlwb kev xav tau tsis tau ceeb toom.

Nrog rau kev siv cyclosporine, fibrates, erythromycin, clarithromycin, cov tshuaj tiv thaiv kab mob thiab tshuaj tua kab mob ntawm pab pawg azole, nicotinic acid thiab nicotinamide, tshuaj uas thaiv cov metabolism hauv kev sib kho los ntawm CYP450 isoenzyme 3A4, thiab / lossis kev thauj tshuaj, cov tshuaj loog ntawm atorvastatin thiab ntshav ntawm lub nce. Thaum sau cov tshuaj no, cov txiaj ntsig uas xav tau thiab qhov kev pheej hmoo ntawm kev kho yuav tsum tau ua tib zoo ntsuas, cov neeg mob yuav tsum tau soj ntsuam kom tsis tu ncua kom paub cov leeg mob lossis tsis muaj zog, tshwj xeeb tshaj yog thawj lub hlis ntawm kev kho mob thiab thaum lub sijhawm nce ntxiv ntawm ib qho tshuaj twg, ib ntus txiav txim siab cov haujlwm ntawm KFK, txawm hais tias qhov kev tswj hwm no tsis tso cai tiv thaiv kev txhim kho ntawm mob myopathy hnyav. Kho txoj kev kho Torvard yuav tsum tsis ua mus ntxiv yog tias muaj qhov cim tseg hauv CPK cov haujlwm lossis yog tias muaj kev lees paub lossis xav tias mob myopathy.

Torvacard tsis muaj qhov teeb meem loj hauv kev kho mob rau qhov kev saib xyuas ntawm terfenadine hauv cov ntshav ntshav, uas yog metabolized feem ntau los ntawm 3A4 CYP450 isoenzyme, hauv qhov no, nws tsis zoo li atorvastatin muaj peev xwm cuam tshuam loj rau pharmacokinetic yam ntawm lwm qhov chaw ntawm CYP450 3A4 isoenzyme. Nrog rau kev siv tib txhij ntawm atorvastatin (10 mg ib hnub ib zaug) thiab azithromycin (500 mg ib hnub ib zaug), qhov concentration ntawm atorvastatin hauv cov ntshav ntshav tsis hloov.

Nrog kev noj ib txhij ntawm atorvastatin thiab cov kev npaj muaj magnesium thiab aluminium hydroxides, qhov concentration ntawm atorvastatin hauv cov ntshav ntshav poob qis li 35%, txawm li cas los xij, cov neeg kawm ntawv qib qis hauv qib LDL-C tsis tau hloov pauv.

Nrog rau kev siv ua ke ntawm colestipol, ntshav ntau ntawm atorvastatin txo tsawg li thaj tsam 25%. Txawm li cas los xij, lipid-txo cov nyhuv ntawm kev sib txuam ntawm atorvastatin thiab colestipol ntau dua qhov ntawm txhua cov tshuaj ib tus zuj zus.

Nrog rau kev siv tib lub sijhawm Torvacard tsis cuam tshuam rau lub pharmacokinetics ntawm phenazone, yog li ntawd, kev sib cuam tshuam nrog lwm cov tshuaj metabolized los ntawm tib CYP450 isoenzymes tsis xav.

Thaum kawm txog kev cuam tshuam ntawm atorvastatin nrog warfarin, cimetidine, phenazone, tsis muaj cov cim ntawm thaj chaw muaj kev cuam tshuam loj tau pom.

Kev siv ib txhij siv cov tshuaj uas txo cov kev ua kom zoo ntawm cov tshuaj hormones endogenous steroid (suav nrog cimetidine, ketoconazole, spironolactone) muaj kev pheej hmoo ntawm kev txo qis cov tshuaj hormones endogenous steroid (ceeb toom yuav tsum tau siv).

Muaj tsis muaj kev cuam tshuam los ntawm kev muaj mob loj ntawm kev sib txuam ntawm atorvastatin nrog cov tshuaj tiv thaiv kab mob, nrog rau estrogens.

Nrog tib lub sijhawm siv ntawm Torvacard ntawm koob tshuaj 80 mg rau ib hnub thiab tshuaj tiv thaiv qhov ncauj muaj norethindrone thiab ethinyl estradiol, qhov nce ntau ntawm cov tshuaj norethindrone thiab ethinyl estradiol tau pom los ntawm kwv yees li 30% thiab 20%, feem. Cov nyhuv no yuav tsum raug txiav txim siab thaum xaiv qhov ncauj tsis haum rau cov poj niam tau txais Torvacard.

Nrog rau kev siv tib txhij ntawm atorvastatin ntawm koob tshuaj 80 mg thiab amlodipine ntawm koob tshuaj 10 mg, pharmacokinetics ntawm atorvastatin hauv lub xeev equilibrium tsis hloov pauv.

Nrog kev tswj hwm rov qab ntawm digoxin thiab atorvastatin ntawm koob tshuaj 10 mg, qhov sib npaug ntawm digoxin hauv cov ntshav ntshav tsis hloov. Txawm li cas los xij, thaum digoxin tau siv nrog kev sib xyaw nrog atorvastatin ntawm ib koob ntawm 80 mg rau ib hnub, qhov siab ntawm digoxin nce ntxiv txog 20%. Cov neeg mob tau txais digoxin ntau ntxiv nrog atorvastatin xav tau kev soj ntsuam.

Kev kawm txog kev sib cuam tshuam nrog lwm yam tshuaj tsis tau ua.

Analogs ntawm cov tshuaj Torvacard

Cov qauv ntawm cov qauv ua haujlwm:

Cov tshuaj hauv cov pab pawg (pharmacological statins):

Kev ntsuas (kev hloov chaw) ntawm torvakard - atoris, krestor, lypimar, lawv cov nqi

Yuav kom txo qis cov roj cholesterol hauv lub cev, cov kws kho mob tsis ib txwm sau los ntawm lub roj rau cov neeg mob. Qee zaum sau ntawv yuav tshuaj los hloov cov tshuaj lossis kab mob sib piv ntawm cov tshuaj no tau sau tseg. Thiab qee tus neeg mob tam sim ntawd muaj ntau cov lus nug txog kev hloov pauv ntawm torvacard nrog cov tsis muaj tshuaj lossis lwm yam tshuaj los ntawm cov pawg statin. Ntxiv nrog rau qhov xav kom sib piv cov nqi thiab nrhiav kom paub ntau npaum li cas cov teeb meem thiab cov tshuaj muaj hauv kev sib pauv tus nqi, nws tseem yuav tsum txiav txim siab seb qhov twg zoo dua thiab ua haujlwm rau kev kho mob. Koj tuaj yeem hloov cov tshuaj no nrog lwm los ntawm tib pab pawg statins. Crestor tsis hloov rau Torvacard. Qhov no yog lwm qhov, ua tiav tshuaj ywj siab, zwm rau tib pawg statins. Nws kuj tseem muaj txiaj ntsig zoo hauv kev txo qib LDL phem. Cov kws kho mob pom zoo kom nyab xeeb siv tus ntoo khaub lig lossis torvakard.

Txhua yam tshuaj uas tau muab coj los hloov torvacard tuaj yeem faib ua pawg:

• Generics - muaj lwm lub npe thoob ntiaj teb
• Cov lus txhais - nquag lossis hloov pauv
• Cov tshuaj Analogs - sib txawv los ntawm pab pawg pharmacological, muaj tib lub npe ATC lossis lub npe

Cov chaw muag tshuaj ib zaug xav rho nyiaj hauv cov ntshav qab zib. Muaj qhov paub tab paub xav txog cov tshuaj niaj hnub European, tab sis lawv ua kom ntsiag to txog nws. No.

Nrhiav seb yuav hloov Torvacard li cas, xyuam xim rau cov hloov pauv hauv qab no, tab sis nco ntsoov tau txais cov lus qhia ntxaws mob ua ntej siv.

Ntsib analogues!

• Atoris yog qhov hloov heev tshaj plaws torvacard. Nws tawm hauv Slovenia. Cov tshuaj kuj tseem siv los txo qhov tsis zoo thiab kom tag nrho cov cholesterol. Tus nqi nruab nrab ntawm atoris ntsiav tshuaj yuav luag zoo tib yam li siv tshuaj yaj yeeb tiag.
• Liprimar belongs rau cov pab pawg ntawm cov lus ua. Qhov no yog txoj hauv kev zoo rau txo qis roj cholesterol. Cov tshuaj yog tsim nyob hauv lub teb chaws Yelemees thiab Ireland. Ntxiv nrog rau qhov niaj zaus koob tshuaj 10 mg, 20 mg, 40 mg, 80 mg tau pom. Qhov ntau thiab ntau npaum cov tshuaj tsuas yog teem los ntawm tus kws kho mob nkaus xwb. Tus nqi nruab nrab rau kev lypimar hauv ntau lub tsev muag tshuaj yog 2-3 zaug kim dua rau Torvacard.
• Tulip feem ntau siv los txo cov roj hauv lub pob nrog kev noj haus. Nws txawm siv tau los kho cov menyuam yaus txij hnub nyoog kaum xyoo. Muaj cov khoom ntim ntawm 30 lossis 90 ntsiav tshuaj hauv tib lub tshuaj raws li Torvacard. Ob yam tshuaj yuav luag nqi.
• Atomax yog Is Nrias teb hloov chaw tshaj plaws. Nws yog tsim los ntawm tuam txhab nto moo Hetero Drags. Hais txog cov tshuaj lipid-txo qis. Cov no yog cov ntsiav tshuaj uas muaj qhov tshuaj ntau npaum 10 lossis 20 mg. Cov nqi nruab nrab yog tib yam li cov ntawv teeb tsa.

Generics thiab analogues yog qhov tsim nyog hloov rau cov tshuaj kho mob tiag tiag, thiab thaum xav tau maj nrawm koj tuaj yeem hloov kho qhov sib npaug, tsis hnov ​​qab sab laj nrog kws kho mob.

Kuv muaj ntshav qab zib tau 31 xyoos. Tam sim no nws muaj kev noj qab nyob zoo lawm. Tab sis, cov tshuaj ntsiav no nkag tsis tau rau cov neeg dog dig, lawv tsis xav muag cov khw muag tshuaj, nws tsis muaj txiaj ntsig rau lawv.

Torvacard lossis Atorvastatin, nws yog ib qho zoo dua los ntawm cov tshuaj noj rau cov cholesterol?

Nrog lub hnub nyoog, tib neeg lub cev tsis rov tsim dua tshiab los ntawm cov tub ntxhais hluas. Yog li, cov neeg laus thiab cov neeg laus tsim kab mob ntawm yuav luag txhua yam hauv nruab nrog cev thiab kab ke.

Cov hlab ntsha feem ntau cuam tshuam rau kev hloov pauv muaj hnub nyoog, thiab vim yog lawv cov chaw hauv zos thoob plaws lub cev, txhua cov ntaub so ntswg raug kev txom nyem - sib txuas, cov leeg, pob txha, thiab tshwj xeeb tshaj yog poob siab.

Atherosclerosis yog kab mob uas cuam tshuam rau cov hlab ntshav ntawm cov ntshav ncig. Qhov no yog qhov kab mob ntawm cov kab mob vascular, nyob rau hauv uas tsim cov nyiaj ntawm cov cholesterol thiab cov kua roj lipoproteins tsawg kawg ntawm cov hlab ntsha tau pom.

Cov tsos mob ntawm tus kab mob pathology yog ua ntej los ntawm kev nce ntshav hauv cov ntshav ntev ntev.

Tus kab mob no nyob hauv peb theem:

• Thawj theem yog tus cwj pwm los ntawm lipid saturation. Hauv qhov no, microdamage mus rau lub intima ntawm phab ntsa vascular thiab kev txo qis hauv cov ntshav khiav nrawm ua si lub luag haujlwm txiav txim siab. Hauv 70% ntawm tus neeg mob, qhov no tau pom ntawm thaj chaw ntawm bifurcation, uas yog, ceg, piv txwv, nyob hauv qis qis ntawm aorta. Nyob rau theem no, lipids hnov ​​mob rau qhov enzymes ntawm qhov cuam tshuam intima thiab txuas rau nws, maj mam tsub zuj zuj,
• Qhov thib ob theem nyob hauv kev txhim kho atherosclerosis yog hu ua lipid sclerosis. Lub sijhawm no yog cim los ntawm qeeb qeeb ntawm atherosclerotic masses, uas yog vim muaj kev loj hlob ntawm cov nqaij mos txuas los ntawm nws. Qeb no yog nrab, uas yog, kev soj ntsuam tuaj yeem pom. Txawm li cas los xij, muaj kev txaus ntshai ntawm kev hloov pauv - cais ntawm qhov ntawm cov txhaws, uas tuaj yeem txhaws lub nkoj thiab ua rau ischemia thiab cov nqaij tuag,
• Atherocalcinosis ua tiav kev txhim kho ntawm tus kabmob. Cov tshuaj ntsev calcium tuaj nrog cov roj ntsha thiab txiav cov quav hniav, ua rau nws cov tawv nqaij tawv thiab tawg. Maj mam, cov tshuaj loj zuj zus tuaj, nws lub suab nce, qhov dej ntws dawb ntws cuam tshuam, mob ntsws ischemia tshwm sim, uas ua rau kev tawm tsam txhawm thiab txhaws nqaj.

Nws tau dav dav ntseeg ntawm cov kws tshawb fawb tias kev kis mob tuaj yeem tsim kev loj hlob ntawm atherosclerosis. Tam sim no muaj kev tshawb nrhiav txog qhov teeb meem no.

Lub hauv paus ntsiab lus tseem ceeb ntawm kev kho mob ntawm hypercholisterinemia yog:

1. txo qhov kev nqus ntawm cov roj hauv lub cev thiab txwv nws cov khoom ua rau muaj endogenous,
2. kho nws txoj kev tshem tawm sai sai los ntawm kev hloov mus rau cov roj ntsha thiab los ntawm cov hnyuv,

Ntxiv rau, nws yog ib qho tsim nyog los kho cov kab mob concomitant - mob ntshav qab zib, mob plawv, mob ntshav siab, mob ntshav hlab plawv.

Yuav xaiv cov tshuaj zoo li cas?

Hauv cov khw muag tshuaj, koj tuaj yeem nrhiav tau ob hom tshuaj. Qhov thib ib yog qhov qub, thawj txoj kev loj hlob ntawm lub chaw tsim tshuaj yeeb tshuaj uas muaj daim ntawv tso cai rau nees nkaum xyoo.

Qhov no txhais tau hais tias yuav luag ib xyoo plaub lub hlis twg, tsuas yog lub tuam txhab no tuaj yeem tsim cov tshuaj no. Kom txog rau thaum lub patent tas sij hawm, kev npaj tshuaj analogue tsis tuaj yeem tshwm nyob rau hauv txee. Tab sis thaum kawg ntawm lub sijhawm no, kev tiv thaiv raug muab tso tseg thiab cov ntawv luam tshwm. Hauv qhov no, qhov qub tseem yog ib qho kev txiav txim ntawm qhov ntau ntau dua.

Qhov laj thawj ntawm no yooj yim piav qhia - rau kev tsim cov khoom lag luam tshwj xeeb, cov kws tshawb fawb tau siv nyiaj ntau txhiab lab nyiaj los mus sim cov chaw kuaj mob ntev ntev thiab lees paub qhov ua tau zoo thiab kev nyab xeeb ntawm ntau cov neeg yeem yeem. Cov txheej txheem yuav siv sij hawm ntau dua kaum xyoo.

Generics (lossis generics), uas yog pab pawg thib ob, yog qhov tseem ceeb clone kev npaj nrog cov yam ntxwv zoo sib xws.

Txhawm rau ua lawv, koj yuav tsum noj mis nyuj tov npaj, ntxiv cov neeg dhau los rau qhov qub, tuaj nrog lub npe kom yooj yim thiab muab tso rau muag.

Cov khoom thev naus laus zis tsis zoo ib yam li thawj cov tshuaj, yog li cov kev hloov pauv hauv tib neeg ua ntau.

Tus nqi yog nyob ntawm ntau yam: cov qauv kev tsim tawm, kev sib txuas ntxiv ntawm cov sib txuas ntxiv, muaj pes tsawg qhov kev sim tshuaj uas nws tau dhau los. Kev tshawb nrhiav tuaj yeem faib ua:

1. Bioequivalent, uas yog, kuaj xyuas qhov yuam kev nrog daim ntawv qhia,
2. Kws Tshuaj - paub tseeb qhov tseeb mechanism ntawm kev txiav txim,
3. Thiab kev kho mob, kawm kev ua haujlwm ntawm cov generics rau tib neeg.

Tus nqi yog ncaj ncaj rau cov naj npawb ntawm cov kev tshawb fawb - uas yog, muaj ntau, muaj cov khoom kim dua.

Hauv cov pab pawg ntawm lipid-txo cov tshuaj, atorvastatin yog thawj. Thaum kuaj mob mus ntev kawg kaum ob lub hlis, nws pom cov lus hauv qab no:

• Qhov siab ntawm qis lipoproteins tsawg dua 55%,
• Cov roj (cholesterol) tag nrho poob 46%,
• Cov qib ntawm cov lipoproteins uas tau nce siab tau nce (qhov no yog "zoo" cov cholesterol, nws tsis txhaws cov hlab ntsha) 4%.

Qhov koob tshuaj uas siv los ntawm cov neeg ua hauj lwm pub dawb yog 10 milligrams ib hnub.

Thaum muab piv rau cov tshuaj feem ntau nrog nws, nws tau pom tias lwm cov statins xav tau ntau dua lub siab xav kom ua tiav cov nyhuv - rau Torvard nws yog 20 milligrams, rau Simvastatin - 40, thiab rau Fluvastatin ntau npaum li 80.

Cov ntaub ntawv no tsis pom zoo nyob hauv daim ntawv luam, ua qhov txawv loj.

Kev xaiv ntawm cov qauv ntau thiab thawj

Cov tshuaj Torvakard yog ib qho tseem ceeb tshaj plaws ntawm Atorvastatin.

Nws tus nqi yog ib nrab ntawm qhov uas ua rau ntau tus neeg nyiam, vim tias cov nyiaj khaws cia yog 50%. Nws tau zoo tshaj tawm, muaj kev txheeb xyuas zoo txog nws, yog li neeg coj nws nrog kev txaus siab.

Cov tshuaj sib txawv heev nyob rau hauv muaj pes tsawg leeg, yog tias nyob rau hauv thawj daim ntawv qhia muaj tsuas yog thawj cov tshuaj atorvastatin thiab kev pabcuam hauv daim ntawv ntawm lactose, tom qab ntawd hauv Torvakard muaj ntau lub koomhaum pabcuam ntxiv.

Cov tshuaj muaj pes tsawg leeg suav nrog:

1. Atorvastatin calcium ntsev, 10 milligrams - cov tshuaj nquag,
2. Croscarmellose sodium - ib qho tshuaj tsis haum uas ua kom cov ntsiav tshuaj tawg hauv plab,
3. Magnesium oxide tiv thaiv clumping,
4. Lactose monohydrate - muab tub lim rau kis tau los ntawm qhov ntau txaus,
5. Monocrystalline kua nplaum yog qhov tsw thiab qhov tsw tsw,
6. Magnesium stearate yog cov khoom coj los tiv thaiv cov khoom ua kom yooj yim rau kev tsim khoom thiab ntim.

Muaj pes tsawg leeg lub plhaub taum muaj xws li:

• titanium dioxide - cov ntxhia ntxhia hauv cov roj nplua,
• talc yog cov khoom txav uas txo qhov ntxhib vim kev adsorption nyob rau saum npoo ntawm granules.

Raws li tuaj yeem pom los ntawm cov keeb kwm yav dhau los, cov tshuaj Torvakard muaj ntau yam ballast tshuaj uas ua kom yuag thiab nws lub cev. Rau ntau yam ntawm cov khoom no, kev tsis haum tshuaj tiv thaiv kab mob tuaj yeem tsim kev tsis haum lossis kev tawm tsam ntawm kev tsis haum, suav txij li khaus ntawm daim tawv nqaij mus rau Quincke's edema, yog li lawv tsis pom zoo kom siv cov tshuaj. Lossis, ntsuas ua ntej nrog kev sim allergenic rau cov tebchaw no kom paub tseeb tias kev noj tshuaj muaj kev nyab xeeb rau kev noj qab haus huv.

Cov neeg uas mob tsis haum mis nyuj yog txwv tsis pub noj yam tshuaj muaj sia txhua yam.

Yog li dab tsi yog qhov txawv ntawm Atorvastatin thiab Torvacard?

Raws li tuaj yeem pom los ntawm cov kev tshawb fawb soj ntsuam, kev tsom xam cov sib xyaw molecular thiab kev phom sij tsis haum, Torvacard yog qis dua me ntsis ntawm Atorvastatin. Qhov no tsis yog qhov xav tsis thoob, vim hais tias cov thev naus laus zis rau kev tsim cov generics txawv ntawm qhov qub, yog li ntawd, cov nyhuv tshuaj kho tau qis dua, thiab qhov yuav tsum tau siv tshuaj ntau dua. Nws cov txiaj ntsig tseem ceeb yog tus nqi, tab sis nws tsim nyog nco ntsoov tias avaricious them ob zaug, thiab koj yuav tsum twv yuav raug tsis txuag ntawm koj kev noj qab haus huv.

Nws puas tsim nyog nws coj cov neeg txawj ntse statins yuav qhia hauv qhov yeeb yaj kiab hauv tsab xov xwm no.

Atoris: lus piav qhia, muaj pes tsawg leeg, thov

Cov tuam txhab muag tshuaj muaj ntau cov tshuaj tawm los tawm tsam atherosclerosis thiab cov muaj roj hauv siab. Yuav xaiv cov txiaj ntsig zoo tshaj plaws thiab nyab xeeb npaum li cas?

Atoris, tshuaj uas txo qis roj hauv lub cev, tseem nrov heev. Nws zwm rau pab pawg ntawm statins. Cov tshuaj muaj nqis yog atorvastatin. Nws inhibits cov synthesis ntawm cov cholesterol los ntawm kev ua kom tsis muaj zog ntawm enzyme HMG CoA reductase, pab txo nws cov qib hauv cov ntshav. Nws txo qis cov lipoproteins tsawg ntawm LDL cov roj cholesterol ua teeb meem rau tib neeg, thiab rov ua dua, nce qhov nce ntawm HDL, txhawb nws cov anti-atherosclerosis. Cov tshuaj nquag Atorvastatin txo cov kev saib xyuas ntawm cov tshuaj uas tsim cov peev txheej ntawm adipose cov nqaij hauv lub cev.

Atoris rau cov statins txog koob thib 3, uas yog, nws ua tau zoo heev.

Muaj nyob rau hauv cov ntsiav tshuaj ntawm 10, 20, 30, 60 thiab 80 ml los ntawm lub tuam txhab Slovenian pharmacological KRKA.
Atoris pom zoo rau kev siv cov neeg mob atherosclerosis thiab cov neeg mob uas muaj lub siab xav ntawm cov roj cholesterol hauv cov ntshav.

Thaum pib, cov tshuaj tau tsim los ua cov khoom lag luam zoo dua ntawm cov khoom kim heev thiab tshawb nrhiav Liprimar cov khoom lag luam tsim los ntawm lub tuam txhab German Pfizer. Tab sis, ua tsaug rau qhov kev ua tau zoo, nws nyob hauv nws lub niche ntawm cov chaw muag tshuaj ntau lawm ntawm statins.

Hloov chaw Atoris

Txhua yam analogues muaj atorvastatin yog cov tshuaj tseem ceeb.

• Liprimar - Pfizer, Lub Tebchaws Yelemees.

Koom tes hauv ntau cov kev sim tshuaj. Nws tau pov thawj nws tus kheej los ua cov khoom siv nyab xeeb thiab siv tau zoo. Muaj tus nqi siab.

• Torvacard - Zentiva, Slovenia.

Muaj pes tsawg leeg zoo tib yam rau Atoris. Nrov hauv cov neeg mob hauv tebchaws Russia.

• Atorvastatin - ZAO Biocom, Alsi Pharma, Vertex - tag nrho cov chaw tsim khoom Lavxias. Cov tshuaj yog nrov heev nyob rau hauv Russia vim tias tus nqi tsawg.

Ntau tus neeg mob xav tias: Atoris lossis Atorvastatin, uas yog qhov zoo dua? Lo lus teb rau lo lus nug no yog tsis muaj dab tsi. Cov tshuaj muaj pes tsawg leeg ntawm ob hom tshuaj yog tib yam tshuaj qub. Qhov no ua rau lawv cov kev ua zoo ib yam. Qhov sib txawv ntawm lawv hauv cov tuam txhab thiab lub teb chaws ntawm kev tsim khoom.

• Atomax - Hetero Tshuaj Txwv, Is Nrias teb. Nws txawv ntawm Atoris nyob ib puag ncig tsuas yog kev kho qis ntawm 10-20 mg. Pom zoo rau kev tiv thaiv ntawm atherosclerosis hauv cov neeg laus.
• Ator - CJSC Vector, Russia.

Nthuav hauv tsuas yog ib qho tshuaj - 20 mg. Nws xav tias yuav tsum tau siv ntau cov ntsiav tshuaj kom tau txais qhov koob uas yuav tsum tau ua.

Kev sib piv nrog lwm cov tshuaj nquag

Cov tshuaj sib xyaw cov tshuaj no suav nrog lwm cov statin.

Livazo - Pierre Fabre Recordati, Fabkis, Ltalis.

Crestor - Russia, Great Britain, Tebchaws Yelemees.

Simgal - Czech koom pheej, Ixayees.

Simvastatin - Serbia, Russia.

Tab sis nws yog tsim nyog kom nco ntsoov tias simvastatin yog thawj-paub tshuaj.

Tsab xov xwm muab los ntawm Filzor.ru

Cov chaw muag tshuaj niaj hnub nthuav tawm kev xaiv loj ntawm lipid-txo cov tshuaj kom txo cov roj cholesterol thiab tiv thaiv atherosclerosis. Feem ntau cov pab pawg ntawm cov tshuaj uas nrov heev nrog cov kws kho mob thiab cov neeg mob yog, ntawm chav kawm, statins. Cov no suav nrog cov tshuaj uas muaj kev cuam tshuam zoo ib yam thiab cov cim qhia tau siv. Zoo li feem ntau lwm cov ntsiav tshuaj, Atoris muaj cov tshuaj tiv thaiv kab mob sib xyaw nrog cov tshuaj uas muaj cov tshuaj tsis zoo sib xws.

Qhia txog ntawm cov tshuaj

- cov tshuaj nrog lipid-txo cov nyhuv, uas hais txog pawg ntau ntawm statins. Lub tuam txhab tsim khoom lag luam - Slovenian chaw tsim tshuaj suav KRKA. Cov tshuaj tivthaiv yam muaj nyob rau hauv cov lus qhia thiab hu ua atorvastatin. Cov tshuaj no nkag mus rau cov hlab ntshav mus rau hauv lub siab thiab muaj kev kho mob hauv hepatocytes. Nws tau teeb tsa hauv cov txheej txheem biochemical ntawm cov roj metabolism hauv lub cev, txwv ib qho ntawm cov enzymes tseem ceeb hauv kev hloov pauv ntawm lub cim rau hauv cov roj (cholesterol) paub tab thiab, thiaj li, txo qhov kev xav ntawm "rog" rog hauv cov ntshav.

Tsis tas li ntawd, Atoris thiab nws cov analogues pab txo cov feem phom sij ntawm cov roj (cholesterol) - LDL thiab VLDL, tsis tsuas yog cuam tshuam rau lawv cov kev sib txuas, tab sis kuj nce kev siv cov lipoproteins los ntawm daim siab ua haujlwm. Yog li, qhov concentration ntawm atherogenic cov rog hauv cov ntshav yog li qub, thiab cov phom sij txaus ntshai hauv cov hlab ntsha tsis tsim. Ob yam no ua rau txo qis kev pheej hmoo ntawm ischemic pathology ntawm lub plawv thiab lub hlwb hauv cov neeg mob atherosclerosis. Raws li cov kev tshawb fawb tau qhia hauv cov lus qhia, hauv cov neeg mob uas muaj cov tsos mob hnyav ntawm myocardial ischemia lossis mob hlwb tsis muaj zog txaus, Atoris txo qis qhov tshwm sim ntawm cov teeb meem phom sij xws li mob stroke lossis lub plawv nres.

Atoris muaj tshwj rau cov qauv hauv cov ntsiav tshuaj. Cov tshuaj yog tus qauv: 30 lossis 90 ntsiav tshuaj, qhov ntau npaum ntawm qhov yuav txawv, raug muab tso rau hauv lub hlwv, muab cov lus qhia rau kev siv thiab tau ntim rau hauv thawv ntawv thawv.

Cov koob tshuaj ntawm cov tshuaj yuav tsum tau tham nyias. Atoris ntsiav tshuaj muaj nyob rau hauv kev lag luam kws tshuaj nrog rau cov npe 10, 20, 30, 60, 80 mg. Tus naj npawb qhia hauv pob thiab hauv cov lus qhia sib raug nrog cov ntsiab lus ntawm cov khoom ua kom nquag plias hauv txhua ntsiav tshuaj.

Ntau yam tshuaj yog yooj yim heev rau xaiv thiab koob kho. Qhov zoo tshaj plaws rau txhua tus neeg mob yog kev teem sijhawm tsawg kawg ntawm cov tshuaj, uas yuav pab tau kom cov qib roj hauv lub cev tsis zoo. Thaum pib ntawm txoj kev kho kom txo qis cov roj cholesterol, txhua tus neeg mob feem ntau tau tshaj 10 mg ntawm Atoris. Tom qab ib hlis ntawm kev noj cov tshuaj tsis tu ncua thiab dhau cov kev tswj hwm kev tswj hwm, cov hauj lwm zoo ntawm kev kho tau raug ntsuas:

• yog tias cov roj (cholesterol) thiab LDL tsawg dua, qhov tshuaj ntawm Atoris pom tias yog txaus,
• yog tias atherogenic feem ntawm lipids yuav nyob rau tib theem lossis nce ntxiv, ces yuav tsum tau txhaj tshuaj kho kom haum (raws li txoj cai, ob npaug).

Cov koob tshuaj ntawm Atoris tuaj yeem xaiv ib tus zuj zus, nce qhov kev mloog zoo ntawm cov tshuaj nquag hauv cov ntsiav tshuaj tsis yog 2, tab sis los ntawm 1.5 npaug. Cov tshuaj noj nrog cov tshuaj qis dua tsis yog tsuas pheej yig dua, tab sis kuj tseem muaj ntau phiv ntau yam.

Lwm qhov txawv tshwj xeeb ntawm Atoris, hauv kev sib piv nrog cov qauv sib piv, yog qhov pov thawj loj rau qhov kev ua haujlwm siab ntawm cov tshuaj. Cov neeg tsim khoom hu rau Atoris tsuas yog cov tshuaj feem ntau uas tau koom nrog ntau dua peb caug qhov kev kuaj mob tseem ceeb uas tau ua pov thawj nws qhov kev nyab xeeb thiab tshuaj muaj txiaj ntsig zoo.

Piv txwv li, kev kawm ntawm INTER-ARS, ua ib txhij nyob rau hauv peb lub teb chaws Europe ntawm 117 tus neeg mob, ua pov thawj Atoris tus kheej tiag tiag nrog tus thawj atorvastatin, qhov tsawg kawg ntawm cov kev mob tshwm sim thiab pom kev kho mob tom qab 3 lub lis piam ntawm kev noj tshuaj.

Txoj kev tshawb no ATLANTICA, tsom mus kawm txog qhov tshwm sim ntawm kev siv tshuaj mus ntev rau cov neeg mob, kuj tau ua tiav rau cov tshuaj: hauv cov neeg mob noj 20 rau 80 mg ntawm Atoris txhua hnub rau 12 hlis, qib ntawm tag nrho cov roj (cholesterol) thiab lipids koom nrog kev tsim cov tshuaj atherosclerotic plaque rov qab mus rau qhov qub. Tsis muaj kev phiv tshwm sim tom qab siv tshuaj.

Atoris yog cov tshuaj uas nrov npe uas tau muab tshuaj rau cov neeg mob uas muaj lub siab thawj thiab theem siab hypercholesterolemia. Txawm li cas los xij, muaj ob peb analogues ntawm cov tshuaj nrog cov tshuaj zoo ib yam thiab cov teeb meem ntawm kev ua. Cov kev sib txawv loj yog nyob rau hauv cov chaw tsim khoom, cov khoom thov tau zoo thiab tus nqi.

Atoris thiab lwm yam statins: kev sib piv ntawm cov nqi tam sim no

Sib piv cov lus ntawm cov nqi rau Atoris thiab lwm yam kev npaj atorvastatin yog qhia hauv qab no.

Ib pob ntawm 30 ntsiav tshuaj yog txaus rau ib hlis ntawm kev nkag mus txhua hnub. Qee cov tshuaj muaj muag hauv 90-100 ntsiav tshuaj. Xws ntim ntawm cov nqe hais nqi yog qhov txaus rau peb-lub hlis txoj kev kho mob.

Txhua cov tshuaj raws atorvastatin ua zoo ib yam - qhov no yog qhov tseeb. Vim li cas cov tshuaj los ntawm cov tuam txhab tsim khoom sib txawv? Nws tsis yog tsuas yog teeb meem ntawm lub chaw muag tshuaj lub npe nrov, cov peev nyiaj tau siv rau kev tshaj tawm thiab kev ua haujlwm ntawm kev faib tshuaj rau hauv cov khw muag tshuaj.

Nws ntseeg tau tias cov tshuaj tsim los ntawm cov tuam txhab loj yog qhov zoo dua thiab kev nyab xeeb dua, txij li cov cuab yeej niaj hnub no thiab cov thev naus laus zis tau siv rau nws cov kev sib txuas.

Hauv kev tshawb nrhiav kev lag luam tom qab ntawm lub npe hu ua generics (pheej yig hloov rau cov khoom qub qub), uas yog tsim los ntawm cov tuam txhab tshuaj me me (tshwj xeeb hauv Is Nrias teb), qhov tsis sib xws yog feem ntau kuaj pom. Cov no suav nrog ib qho me me ntawm cov tshuaj yeeb dej caw hauv cov ntsiav tshuaj tshaj li cov lus teev tseg, cov tshuaj ntxuav dej tsis txaus ntawm cov khoom. Hauv qhov no, tus nqi qis tuaj yeem ua qhov kev pabcuam tsis zoo: tus neeg mob tsis tau txais cov nyhuv tshuaj uas nws suav tau, lossis tau txais tsis zoo. Yog li, cov kev xaiv ntawm cov nyiaj ntawm ntau cov zoo sib xws yuav tsum tau ua txoj haujlwm ncaj ncees, tshuaj xyuas cov kev tshawb fawb soj ntsuam tsis tu ncua thiab tshuaj xyuas cov kws kho mob thiab cov neeg mob. Los ntawm kev yuav cov tuam txhab loj uas muaj npe, koj tuaj yeem ntseeg tau qhov zoo thiab kev nyab xeeb ntawm cov tshuaj.

Atoris yog yeeb tshuaj los ntawm cov pab pawg neeg ntawm statins uas muaj lipid-txo qis (txo qis lipid rog feem) cov nyhuv. Cov tshuaj muaj txiaj ntsig ntawm Atoris yog Atorvastatin. Atoris yog ua los ntawm lub tuam txhab Krka hnub Novo Mesto ”hauv Slovenia. Cov tshuaj yog qhov nrov heev ntawm cov kws kho mob dav dav thiab tau dav siv rau cov neeg mob uas muaj cov kab mob atherosclerotic. Atoris tau nthuav tawm hauv cov khw muag tshuaj hauv ntau qhov ntau - 10, 20, 30, 40, 80 mg. Cov tshuaj nyob rau hauv lub npe lag luam Atorvastatin yog ib qho tseeb ntawm Atoris. Atorvastatin yog tsim los ntawm ntau qhov chaw lag luam hauv tsev thiab txawv teb chaws. Ntawd yog, qhov tseeb, Atorvastatin thiab Atoris yog ib qho thiab zoo ib yam.

Hauv kev kho mob ntawm atorvastatin, cov ntsiab lus ntawm lipoproteins hauv tib neeg lub cev txo qis

Cov teeb meem Pharmacological

Cov tshuaj ua ke ntawm ob qho tshuaj - Atorvastatin, qhia txog cov teebmeem tshuaj hauv qab no:

• txo qhov concentration ntawm cov roj cholesterol hauv ntshav ntshav,
• txo cov ntshav lipoproteins ntshav,
• inhibits kev loj hlob ntawm vascular phab ntsa hlwb,
• muaj cov kev nthuav dav hauv cov hlab ntsha,
• cuam ​​tshuam cov viscosity ntawm cov ntshav, txo nws thiab inhibiting qhov kev txiav txim ntawm qee co Cheebtsam coagulation,
• txo txoj kev txhim kho cov teeb meem cuam tshuam nrog ischemia.

Vim qhov peculiarity ntawm pharmacological kev txiav txim siab, cov tshuaj statin feem ntau yog kho nyob rau hauv neeg laus thiab hnub nyoog laus, tsawg dua rau cov neeg hluas.

Kev ntsuas rau statins

Cov cim tseem ceeb rau kev teem caij cov tshuaj muaj atorvastatin yog:

• Thawj cov rog hauv cov ntshav siab.
• Qhov nce ntawm cov ntshav lipids ntawm ntau yam chiv keeb.
• Thawj tiv thaiv kev ntsuas ntawm ischemic muaj teeb meem rau cov neeg mob uas tsis muaj duab pom tseeb ntawm cov kab mob plawv.
• Kev tiv thaiv ntawm cov txheej txheem ischemic rov qab tom qab mob stroke, mob plawv nres, exacerbation ntawm angina pectoris.

Cov roj (cholesterol) tsawg dua txhais tau tias muaj tsawg dua cov ischemic teeb meem

Ib qho tshuaj ntawm cov tshuaj muaj cov statins yog lub caij lawv tau txais. Hauv cov theem pib ntawm kev kho mob, kev noj ib tug neeg twg raug xaiv los tswj hwm theem ntawm cov cholesterol hauv cov ntshav. Tom qab xaiv ib qho kev kho mob txaus, cov tshuaj tau raug sau nyob rau hauv kev kawm ntev, qee zaum rau lub neej nrog kev tshuaj xyuas lub sijhawm ntawm cov ntshav kuaj tsis tau.

Kev siv cov tshuaj atorvastatin feem ntau ua rau kom muaj txiaj ntsig zoo hauv kev txo qis cov roj (cholesterol) thiab tiv thaiv cov teebmeem ischemic.

Cov Yuav Tsum Muaj

Zoo li txhua yam tshuaj uas muaj cov nyhuv pharmacological, Atorvastatin muaj cov tshuaj contraindications. Cov tshuaj tsis tuaj yeem raug samfwm raws li yam hauv qab no:

• Kev mob siab rau daim siab nyob hauv theem nquag.
• Hloov pauv hauv cov roj ntsha biochemical ntawm lub siab ntawm cov keeb kwm.
• Intolerance rau cov tshuaj tiv thaiv los ntawm cov tshuaj lossis excipients.
• Cev xeeb tub nyob rau hauv ib hlis twg, nrog rau lub sijhawm pub niam mis.
• Cov menyuam yaus thiab cov tub ntxhais hluas hnub nyoog qis dua 18 xyoo.
• Lub sijhawm cev xeeb tub.
• Ua xua rau cov txiv laum huab xeeb thiab kua taum.

Hauv cov xwm txheej saum toj no, kev teem caij Atorvastatin tsis raug qhia. Ntxiv rau, kev saib xyuas yuav tsum tau siv nyob rau hauv kev siv cov tshuaj rau cov kab mob cuam tshuam nrog cov teeb meem hauv lub cev, mob endocrine, kev quav dej cawv los yog kev haus dej haus cawv ntau dhau, decompensated epilepsy, keeb kwm ntawm kab mob siab, mob kis, nrog cov ntshav qis thiab dej electrolyte kev ntxhov siab. Ntawd yog, nrog cov kab mob pathological no, kev siv cov tshuaj statin yog ua tau, tab sis nyob rau hauv kev tswj hwm nruj thiab nrog kev saib xyuas ntawm txhua qhov tsim nyog yuav tau ceev faj.

Kev phiv tshuaj

Txwv tsis pub, txoj kev loj hlob ntawm kev mob sab yam tsis zoo, xws li:

• Lub paj hlwb tuaj yeem hnov ​​mob nrog rau qhov tshwm sim ntawm mob taub hau, poob siab, asthenic syndrome, insomnia, loog ntawm ntau qhov chaw ntawm lub cev, qhov tsos ntawm "Goose pob", nce tactile rhiab heev, nco ib feem, tsis nco qab.
• Lub plawv thiab cov hlab ntsha - kev mob plawv hauv plawv, tsis tshua muaj ntshav siab lossis mob ntshav siab, mob taub hau mob taub hau, muaj ntau yam mob plawv dhia tsis zoo.
• Los ntawm cov txheej txheem hauv plab - xeev siab, kub siab, ntuav, ntuav, mob hauv ntu epigastrium thiab txoj cai hypochondrium, mob plab, cem quav lossis zawv plab. Ua tau exacerbation ntawm pancreatitis ntev, mob siab, cholecystitis. Tsis tshua muaj - kev loj hlob ntawm daim siab tsis ua haujlwm.
• Genitourinary system - txo qis libido, potency, lub raum tsis ua haujlwm.
• Cov tsos mob ntawm kev sib koom ua ke, mob ntawm cov leeg thiab pob txha, cov txheej txheem pathological hauv cov leeg, mob hauv ntau qhov chaw ntawm nqaj qaum.
• Cov tawv nqaij ua pob nrog cov ntsiab lus me, khaus tawv.
• Los ntawm cov kab mob hematopoietic - cov cim qhia ntawm thrombocytopenia.

Yuav tsum kawm cov ntshav roj hauv ntshav tas mus li txhawm rau kom nkag siab qhov kev kho mob zoo npaum li cas (ntshav pub tsawg kawg ib hlis ib zaug)

Yog tias, tawm tsam cov keeb kwm yav dhau los ntawm kev noj tshuaj Atorvastatin lossis Atoris, tsawg kawg ib qho ntawm cov kev mob tsis tsim nyog tshwm sim, tom qab ntawd cov tshuaj yuav tsum tau txiav thiab tam sim ntawd nrhiav kev pab kho mob. Tus kws kho mob yuav ua ib qho kev txiav txim siab - txo qis ntau npaum, hloov cov tshuaj nrog lwm lossis tshem tawm tag nrho kev siv statins. Raws li txoj cai, tom qab kev kho ntawm koob tshuaj txhua hnub ntawm Atorvastatin lossis nws tshem tawm txoj haujlwm, qhov kev tshaj tawm ntawm qhov tsis xav tau yog qhov txo lossis lawv ploj tag.

Yog li, Atorvastatin lossis Atoris, qhov twg zoo dua rau xaiv? Txij li thaum ob qho tshuaj yeeb tshuaj muaj tib cov tshuaj nquag, ntsig txog, lawv muaj tib lub txiaj ntsig pharmacological. Ob qho tshuaj tsis yog qhov qub, uas yog, Atorvastatin thiab Atoris yog luam tawm cov ntawv luam ntawm tus thawj Liprimar tshuaj. Raws li kev ntseeg dav dav tias cov tshuaj qub yog ib qho zoo dua li qhov hu ua generics, Atoris thiab Atorvastatin nyob hauv txoj haujlwm sib luag.

Txawm li cas los xij, ntawm cov kws kho mob, nrog rau cov neeg mob, muaj ib qho kev ntseeg siab ntxiv uas siv tshuaj txawv teb chaws zoo dua li cov tshuaj hauv tsev. Cov neeg ua raws ntawm txoj kev xav no nyiam xaiv Atoris.

Cov nyhuv antiatherosclerotic ntawm Atoris nce vim yog lub peev xwm ntawm cov tshuaj atorvastine cuam tshuam rau cov metabolism ntawm macrophages thiab qhov inhibition ntawm cov synthesis ntawm isoprenoids, uas ua rau loj hlob ntawm vascular txheej hlwb.

Hais txog ntawm tus nqi ntawm statins, nws yuav tsum raug sau tseg tias Atoris nyob rau nruab nrab tus nqi nruab nrab ntawm lwm cov tshuaj muaj Atorvastatin. Cov tshuaj nyob rau hauv lub npe kev lag luam Atorvastatin tuaj yeem muas ntau pheej yig dua - qhov no yog ib qho ntawm qhov zoo ntawm Atorvastatin tshaj Atoris. Txawm li cas los xij, kev xaiv yog xaiv los ntawm tus neeg mob uas tau sau cov tshuaj muaj Atorvastatin. Rau ib tus neeg, qhov muaj feem thib yuav yog tus nqi ntawm cov tshuaj, rau lwm tus - kev xav ntawm kws kho mob lossis tus kws tshaj lij hauv khw muag tshuaj, ib feem peb - ​​yuav tsom mus rau kev tshaj tawm lossis kev tawm tswv yim ntawm cov neeg txheeb ze thiab phooj ywg. Qhov tseem ceeb tshaj plaws yog xaiv cov tshuaj uas tsis yog cuam tshuam txog statins, suav nrog cov tshuaj nquag uas tus kws kho mob tau hais tseg.

Cov no suav nrog cov tshuaj uas muaj kev cuam tshuam zoo ib yam thiab cov cim qhia tau siv. Zoo li feem ntau lwm cov ntsiav tshuaj, Atoris muaj cov tshuaj tiv thaiv kab mob sib xyaw nrog cov tshuaj uas muaj cov tshuaj tsis zoo sib xws.

Crestor: cov lus qhia rau kev siv, analogues, cov nqi thiab tshuaj xyuas

Koj tuaj yeem xav zoo nyob hauv koj lub neej tsis xws luag, thiab tom qab soj ntsuam, kawm txog hyperlipidemia - cov ntsiab lus ntawm cov roj cholesterol thiab triglycerides hauv cov ntshav. Kev mob asymptomatic ua rau muaj kev pheej hmoo loj ntawm cov quav txaij atherosclerotic plaques - cov kev xav ua ntej ntawm kev mob plawv thiab mob nkees.

Krestor, ib qho tshuaj zoo ntawm cov cim tshiab, tsim los ua kom cov lipid metabolism zoo li qub, yuav pab tiv thaiv kev phom sij.

Muaj pes tsawg leeg thiab noj ntau npaum

Tus ntoo khaub lig tau muag nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj. Nyob ntawm seb cov tshuaj siv los ntawm cov tshuaj nquag, ntau hom tshuaj yog tsim:

1. Cov cim hauv daj thiab sau nrog ZD4522 5 yog convex, puag ncig, muaj 5 g ntawm rosuvastatin.
2. Crestor paj yeeb cov xim zoo li zoo sib xyaw nrog ZD muaj 10 mg ntawm cov tshuaj nquag.
3. Hauv tib hom ntsiav tshuaj nrog inscription ZD– rosuvastatin 20g.
4. Qhov siab tshaj plaws ntawm cov tshuaj nquag (49 mg) yog hauv cov qe liab cov ntsiav tshuaj nrog cov cim ZD4522.

Txhua hom tshuaj noj (suav nrog tshuaj analogues) yog nruj tshuaj

Cov Tshuaj Hauv Tshuaj

Krestor inhibits HMG-CoA reductase, ib qho enzyme uas tswj kev tsim cov mevalonate, cov roj cholesterol ua ntej. Rosuvastatin ua haujlwm nyob rau hauv daim siab - ib qho ntawm lub ntsiab hom kabmob.

Statin txo cov lipoproteins ntau nrog qhov tsawg thiab tsis tshua muaj siab los ntawm kev txwv lawv cov synthesis, ntxiv rau txhim kho HDL ntxiv rau kom sib luag thiab catabolism ntawm LDL. Raws li qhov tshwm sim, qib ntawm cov roj (cholesterol) tag nrho, LDL thiab triglycerides tsawg dua.Nyob rau tib lub sijhawm, qhov concentration ntawm HDL nce.

Rosuvastatin ua tau zoo rau hypercholesterolemia hauv kev sib xyaw nrog lossis tsis muaj hypertriglyceridemia, rau cov neeg mob uas tsis hais poj niam txiv neej, hnub nyoog thiab haiv neeg.

Cov txiaj ntsig ntawm kev siv Krestor, kev txiav txim siab los ntawm cov lus tawm tswv yim los ntawm cov neeg koom nrog kev tshawb fawb, raug pom los ntawm qhov kawg ntawm thawj lub lim tiam ntawm qhov kev kawm, tab sis qhov tshwm sim siab tshaj (dhau 90%) tuaj yeem pom tsuas yog tom qab 2-4 lub lim tiam ntawm kev siv tas li.

Tsis zoo li qee qhov analogues, Krestor muaj qhov tsawg kawg ntawm qhov tsis zoo ntawm daim siab. Siv nws ua ke nrog kev noj zaub mov roj kom tsawg thiab lwm yam tshuaj noj kom txo cov roj cholesterol.

Cov Tshuaj Pharmacokinetics

• Xuas. Qhov siab tshaj plaws ntshav ntshav statin cov ntsiab lus tau pom 5 teev tom qab siv sab hauv. Lub bioavailability ntawm cov tshuaj yog txog 20%.
• Kev xa Khoom. Rau feem ntau, tus ntoo khaub lig ntes lub siab - lub koomhaum loj uas cov roj (cholesterol) raug tsim tawm thiab LDL pom tshwm sim. Nws qhov faib khoom yog 134 litres. Txog li 90% ntawm cov tshuaj khi rau cov ntshav protein, feem ntau yog albumin.
• Cov metabolism hauv ntawm Krestor yog qhov tsis lees paub (txog li 10%). Rosuvastatin tso nyiaj rau ntau dua 90% ntawm cov haujlwm ntawm cov roj ntsha tiv thaiv kab mob ntawm HMG-CoA reductase.
• Chaw Sau Ntawv. Lub cev tshem tawm txog li 90% ntawm cov tshuaj Krestor los ntawm cov hnyuv nrog quav, cov seem yog tshem nrog cov zis. Kev tshem tawm ib nrab-lub neej tsis nyob ntawm seb tsuas tshuaj thiab ua rau 19 teev.
• Tej pawg tshwj xeeb ntawm cov neeg mob. Lub hnub nyoog lossis poj niam txiv neej tsis cuam tshuam rau statin pharmacokinetics. Cov neeg sib txawv tseem ceeb ntawm cov neeg sawv cev ntawm cov European thiab Negroid haiv neeg tsis pom, thaum ntawm cov neeg nyob hauv thaj av Asia (Suav, Nyij Pooj, Nyab Laj, Tebchaws Philippines), qhov tseem ceeb ntawm AUC thiab C max yog ob zaug siab dua. Pharmacokinetic tsis muaj rau cov menyuam yaus uas muaj heterozygous tsev neeg hypercholesterolemia tsis tau txiav txim siab tag nrho. Hauv cov neeg mob uas tsis tshua mob mus rau lub raum lub raum tsis ua haujlwm, tsis pom muaj kev hloov dab tsi hauv cov qib statin. Hauv daim ntawv loj, cov ntsiab lus ntawm rosuvastatin hauv ntshav nce ntxiv 3 zaug, metabolite - 9 npaug piv nrog pawg tswj hwm ntawm cov neeg ua haujlwm noj qab haus huv. Thaum kuaj xyuas cov neeg mob uas lub siab pathologies, kev hloov pauv ntawm kev kho mob nrog rosuvastatin tsis tau pom hauv cov tib neeg uas muaj qhov ntsuas txog 7 rau ntawm Child-Pugh nplai. Cov kev paub ntawm kev kho cov neeg mob nrog cov ntawv loj nrog Krestor tsis xav txog.

Leej twg yog Crestor qhia

Thaum hloov Krestor nrog analogues, nws yog ib qho tsim nyog kom paub meej raws li cov xwm txheej lawv siv.

Thawj cov tshuaj qhia:

• Nrog hypercholesterolemia (thawj hom ntawv lossis tsev neeg homozygous),
• Rau kev tiv thaiv mob stroke,
• Nrog rau kev sib xyaw hypercholesterolemia,
• Rau kev tiv thaiv ntawm lub plawv nres,
• Cov neeg mob atherosclerosis,
• Nrog hypertriglyceridemia.

Yuav thov li cas

Txoj kev kho mob thiab kev noj tshuaj yog tsim los ntawm tus kws kho mob raws li kev soj ntsuam, lub xeev kev noj qab haus huv, kab mob concomitant.

Cov kev cai dav dav rau kev siv Crestor:

• Cov ntsiav tshuaj tsis tas yuav tsum zuaj.
• Lub sijhawm txais tos - txhua qhov yooj yim, cov txiaj ntsig siab tshaj plaws tuaj yeem tau txais los ntawm kev siv thaum yav tsaus ntuj, vim tias feem ntau cov roj cholesterol yog tsim thaum hmo ntuj.
• Noj mov tsis cuam tshuam rau qhov ua tau zoo ntawm kev noj tshuaj.
• Ua ntej pib ntawm chav kawm, tus neeg mob yuav tsum hloov mus rau kev noj zaub mov kom tsis txhob rog, uas yuav tsum tau saib xyuas tas li.
• Thawj koob tshuaj Crestor (5-10g / hnub) tau xaiv ib tus zuj zus. Yog tias cov txiaj ntsig tsis tau raws li kev cia siab, koj tuaj yeem hloov kho qhov koob tshuaj rau 20 mg / hnub., Tab sis tsis ntxov dua ib hlis tom qab. Qhov siab tshaj plaws qhov siab tshaj plaws (40 mg / hnub) yog tsuas yog muaj kev pheej hmoo siab ntawm kev mob vascular thiab lub plawv dhia tsis zoo. Ib tus neeg mob uas muaj mob hypercholesterolemia yuav tsum muaj kev saib xyuas hauv tsev kho mob tas mus li, vim tias qhov feem ntau ntawm cov kev mob tshwm sim yuav loj tuaj. Kev soj ntsuam ntawm lipid profile cov ntaub ntawv txhawm rau txhim kho cov chav kawm ntawm txoj kev kho yuav tsum tau ua txhua 2-4 lub lis piam.

Yog tias dhau ntawm kev siv ntau dhau, ib qho tshuaj tiv thaiv tshwj xeeb tsis siv. Txoj kev kho yog mob tshwm sim, coj mus rau hauv qhov nruab nrab ntawm kev lom. Yog tias tsim nyog, nqis tes pab txhawb.

Sab sij huam

Nrog kev soj ntsuam nruj ntawm cov lus pom zoo los ntawm tus kws kho mob koom, cov neeg mob tsis tshua yws txog qhov yuav tshwm sim tsis txaus ntseeg los ntawm kev siv Krestor. Thiab tseem, cov lus qhia rau kev siv ceeb toom ntawm qhov yuav ua rau tsis muaj qhov tsis haum. Cov ntaub ntawv yog raws cov kev tshawb fawb soj ntsuam.

tsis zoo pw tsaug zog.

Ntawv thov kev txwv

Statin muaj ib tug xov tooj ntawm cov contraindications ntsig txog:

• Nrog lub siab rhiab heev rau rosuvastatin,
• Cov theem nquag muaj kab mob siab,
• Mob raum tsis ua haujlwm.
• Keeb kwm ntawm myopathy,
• Kho kho nrog cyclosporine,
• Cev xeeb tub thiab pub niam mis,
• Tsis muaj tshuaj tiv thaiv txaus rau lub sijhawm muaj me nyuam,
• Kev nthuav dav los tsim cov kev mob myotoxic.

Rau cov ntsiav tshuaj hnyav 40 g, ntxiv rau cov npe uas teev contraindications, tseem muaj kev txwv ntxiv:

• Ntshav Qab Zib
• Kab mob hauv cov keeb kwm tus kheej lossis tsev neeg keeb kwm
• Kev quav cawv
• Myotoxicity cuam tshuam nrog cawv ntawm lwm yam tshuaj
• Cov xwm txheej ua rau muaj kev nce qib hauv rosuvastatin,
• Concurrent kom tsawg ntawm fibrates,
• Cov neeg mob ntawm haiv neeg Esxias.

Sib xyaw nrog lwm yam tshuaj

Kev siv tshuaj tsis sib haum nrog cov kev kho nyuaj muaj qhov sib txawv ntawm cov dej num ntawm rosuvastatin.

1. Cov tib neeg teem caij sib deev ntawm Crestor nrog cov tshuaj tiv thaiv kab mob uas tiv thaiv kev thauj cov protein yog txaus ntshai vim qhov nce ntawm cov ntsiab lus ntawm rosuvastatin nyob rau hauv cov hlab ntshav thiab qhov muaj peev xwm ntawm kev tsim myopathy.
2. Nrog rau kev tswj hwm tib txhij ntawm Cyclosporin thiab Krestor, AUC ntawm tom kawg yog 7 zaug siab dua (piv nrog pawg tswj hwm ntawm cov neeg koom nrog kev noj qab haus huv). Qib ntawm cyclosporine tseem nyob li qub.
3. Tsis muaj cov ntaub ntawv qhia kiag, tab sis kev sib koom ua ke ntawm kev siv cov tshuaj tiv thaiv protease thiab rosuvastatin tuaj yeem ua rau muaj kev cuam tshuam ntau ntxiv tom qab. Yog tias tsim nyog, hauv kev kho mob zoo li no nws yog ib qho tsim nyog yuav tsum ua tib zoo xav txog qhov tshuaj ntawm Krestor kom nws qhov kev cia siab loj dua tsis dhau tus cai.
4. Thaum Krestor ua ke nrog hemphibrolysis, C lub txiaj ntsig ntawm rosuvastatin thiab AUC nce 2 zaug. Nrog lub sijhawm sib law liag ntawm fibrates, ntau kawg noj (40 mg / hnub) tsis suav nrog.
5. Kev sib cuam tshuam ntawm Krestor thiab ezetimibe raug sim nyob rau ntawm tib lub sijhawm - 10 mg / hnub. txhua yam. Nrog hypercholisterinemia, qhov no ua rau muaj qhov nce 1.2-npaug hauv AUC ntawm rosuvastatin.
6. Kev sib txuam siv ntawm antacids thiab Krestor txo cov ntsiab lus statin hauv cov ntshav los ntawm 2 zaug. Yog tias cov tshuaj no tau noj ncua sijhawm ntawm 2 teev, qhov cuam tshuam tsawg dua.
7. Erythromycin ua kom lub plab hnyuv ntxiv, yog li ntawd, thaum siv ua ke nrog Krestor, AUC ntawm tom kawg poob qis los ntawm 20%, thiab C max - los ntawm 30%.
8. Cov kev sim paub tseeb tias Krestor tsis inhibit thiab tsis txhawb qhov cytochrome P450 enzymes, yog li tsis muaj kev cuam tshuam loj hauv chaw kho mob nrog lawv yuav tsum tau txais.

Yog tias xav tau kev kho mob nyuaj nrog Crestor thiab lwm yam tshuaj, cov tshuaj ntawm statin tau raug kho, pib nrog 5 mg / cm2. Qhov siab tshaj plaws txhua hnub ntawm rosuvastatin yog teev kom nws cov kev npaj siab tsis tshaj qhov uas tau tsau thaum lub sij hawm monotherapy nrog kev noj tshuaj ntawm 40 mg / hnub.

Crestor: analogues

Ntau yam analogues yog tsim nyob rau hauv lub hauv paus ntawm rosuvastatin, tab sis tus kws kho mob yuav tsum coj lawv mus rau hauv tus account, noj rau hauv lub xeev tshwj xeeb ntawm kev noj qab haus huv ntawm tus neeg mob tshwj xeeb.

Ntxiv rau Rosuvastatin, nws tuaj yeem siv:

Rau Krestor thiab nws cov analogues, tus nqi hauv cov khw muag tshuaj online yog txawv:

• Feem ntau Akorta No. 30 (10 mg) - cov kev xaiv nyiaj txiag tshaj plaws: 511.40 rubles.,
• Tus nqi ntawm cov analog ntawm Mertenil No. 30 (10 mg) - 663 rubles.,
• Cov tshuaj Rosuvastatin No. 30 (10 mg) muaj rau 478 rubles.,
• Rau tus thawj Krestor statin tooj 28 (10 mg), tus nqi yog 1676 rubles.,
• Genort Acorta No. 30 (20 mg) rau ntawm qhov nruab nrab tuaj yeem yuam kom 1049 rubles.,
• Mertenil analogue No. 30 (20 mg) tuaj yeem muas rau 1045 rubles.,
• Rosuvastatin No. 30 (20 mg) - rau 622 rubles.,
• Rau Crestor Zauv 28 (20 mg), tus nqi yog 2825 rubles.

Nyeem ntxiv txog kev pheej yig ntxaws rau cov tshuaj Crestor - hauv daim yeeb yaj kiab no

Dab tsi ua kws kho mob thiab cov neeg mob xav txog Crestor

Txog Krestor, kev tshuaj xyuas ntawm cov kws kho mob thiab cov neeg mob sib luag: tshuaj yog ib qho ua tau zoo, muaj kev tiv thaiv zoo. Cov kws kho mob nco ntsoov cov pov thawj loj thiab cov kev paub ntawm tus kheej ntawm kev vam meej kev siv rosuvastatin.

Yog tias cov peev nyiaj tso cai, nws zoo dua los yuav cov tshuaj qub. Thawj qhov tshiab ntawm rosuvastatin yog Krestor, nws yog rau nws tias kev sim tau nqa nrog kev ntsuas kev tuag ntawm cov kab mob plawv. Rau cov generics, tsis muaj cov ntaub ntawv zoo li no, tab sis ib qho khoom plig zoo yuav tsum muaj los txhim kho lipid profile, txawm hais tias tsis tau ua li ntawd. Kuv yuav tsum tau hais tias statins tsis raug coj los txo qis LDL, tab sis txhawm rau tiv thaiv cov hlab ntsha tawg thiab plawv nres. Kev siv lub neej muaj sia yuav tsum tau siv mus txuas ntxiv.

Koj tuaj yeem kawm txog Asmeskas kev paub txog kev siv Krestor los ntawm "Kev Siv Tshuaj Rau Cov Neeg Noj Qab Nyob Zoo".

Atoris - analogues

Txo cov qib triglycerides, lipids thiab cov roj cholesterol hauv ntshav ntshav, statins yog tshuaj. Atoris tseem hais txog lawv - cov tshuaj analogues ntawm cov tshuaj yuav tsum muaj thaum tsis txaus siab rau cov tshuaj no lossis yog tias, rau qee qhov, nws tsis tuaj yeem yuav nws. Nws yog tsim nyog sau cia tias ntau cov generics muaj ntau pheej yig dua.

Analogues ntawm cov tshuaj Atoris

Qhov npaj tau nthuav tawm yog tsim los ntawm atorvastatin calcium - ib yam khoom tsim los txo cov kev kub siab ntawm cov lipids hauv cov ntshav. Atoris tseem ua cov tshuaj antisclerotic rau ntawm cov phab ntsa ntawm cov hlab ntshav, txo cov viscosity thiab ntom ntawm ntshav, txhim kho hemodynamics, thiab txo qhov kev pheej hmoo ntawm kev tsim kab mob plawv.

Cov tshuaj hauv qab no muaj cov txiaj ntsig zoo thiab muaj pes tsawg leeg:

Qhov twg yog qhov ua tau zoo dua thiab ua haujlwm zoo dua - Atoris lossis Torvakard?

Ob qho tshuaj nyob rau hauv kev txiav txim siab tau txiav txim siab los ntawm tib yam muaj txiaj ntsig, qhov sib xyaw ua ke ntawm cov khoom xyaw ntxiv kuj zoo ib yam. Cov kws kho plawv ntseeg tias tsis muaj qhov sib txawv ntawm cov tshuaj, qhov sib txawv ntawm tus nqi yog tias Torvard yog me ntsis pheej yig dua, txawm tias qhov siab tshaj (40 mg).

Qhov twg yog qhov zoo dua mus yuav - Atorvastatin lossis Atoris?

Cov tshuaj no tseem muaj qhov muaj pes tsawg leeg, tso tawm hauv daim ntawv thiab cov ntsiab lus ntawm cov tshuaj. Atorvastatin feem ntau nyiam, vim tias nws zoo dua tiv thaiv thiab ua rau muaj kev cuam tshuam tsawg dua. Hauv qhov xwm txheej no, tus neeg sawv cev yog tus neeg siv nyiaj ntau dua li Atoris, uas tau piav qhia los ntawm qib siab ntawm kev ua kom huv ntawm cov tshuaj ntawm cov ntsiav tshuaj.

Krestor lossis Atoris - qhov twg zoo dua?

Thawj cov tshuaj qhia tau raws li lwm cov tshuaj - rosuvastatin. Nws ua haujlwm zoo ib yam li Atoris, tab sis kwv yees qhov tshuaj tsawg dua, vim tias 5 mg ntawm rosuvastatin sib raug rau lub zog ntawm 10 mg ntawm atorvastatin.

Yog li, Krestor tau suav hais tias yog ib qho tshuaj yooj yim dua, uas tuaj yeem siv sij hawm tsawg dua. Nyob rau tib lub sijhawm, nws raug nqi ntau dua li Atoris, txog 2.5 npaug.

Zoo tshaj Atoris lossis Liprimar, thiab dab tsi yog qhov zoo dua los yuav?

Cov tshuaj siv sib piv tau ua rau lub hauv paus ntawm atorvastatin. Ntawm qhov zoo ntawm Liprimar nws yog ib qho tsim nyog sau cia:

• cov tshuaj loj dua (10, 20, 40 thiab 80 mg),
• zoo tshuaj ntxuav cov khoom xyaw, uas muab kev pheej hmoo tsawg heev rau cov kev mob tshwm sim,
• zoo thev taus
• siab bioavailability thiab yooj yim.

Txawm li cas los xij, Liprimar tsis tshua muaj tshuaj vim los ntawm tus nqi siab, nws yog 4.5 npaug tshaj li Atoris.

Dab tsi yog qhov zoo rau haus - Atoris lossis Simvastatin?

Cov tshuaj thov muaj cov khoom siv sib txawv, thiab kom ua tiav cov txiaj ntsig xav kom zoo ntawm simvastatin, 20 mg yuav tsum ua tiav, thaum atorvastatin yuav tsum 10 mg.

Tsis muaj qhov sib txawv ntawm cov tshuaj, tshwj tsis yog rau lawv cov nqi. Atoris raug nqi li 4 npaug kim. Thaum xaiv ntawm nws thiab Simvastatin, nws yog ib qho tseem ceeb uas yuav tsum tau coj mus rau hauv tus kheej tus yam ntxwv ntawm tus neeg mob, muaj kev tawm tsam tsis haum thiab muaj qhov tsis haum rau cov tshuaj ntawm cov tshuaj.

Roxer lossis Atoris - uas yog ib qho zoo?

Cov tshuaj sib xyaw nrog cov tshuaj no kuj tseem txawv, roxuvastatin yog lub hauv paus ntawm Roxers.Raws li twb tau hais lawm, cov tshuaj no yog qhov zoo dua, vim tias nws ua tau zoo dua, tsis tas yuav tsum tau tswj hwm ntau zaus thiab noj tshuaj ntau. Ntau tus kws kho mob tau sau ntawv rau Roxer ntau dua, vim tias cov tshuaj no, ntxiv rau kev ua haujlwm zoo, nws pheej yig heev, nws yog 2 zaug pheej yig dua li Atoris.

Luam cov ntaub ntawv tso cai tsuas yog muaj qhov ncaj qha thiab muaj tus lej txuas rau cov khoom siv

Cov tshuaj analogue zoo tshaj plaws ntawm Liprimar: kev sib piv ntawm cov tshuaj thiab tshuaj xyuas txog lawv

Liprimar yog ib cov tshuaj sai sai uas ua rau cov ntshav cov roj tsawg. Noj tshuaj pab txo txoj kev pheej hmoo ntawm kev tuag plawv mob plawv, normalizes kev ua haujlwm plawv thiab txhim kho kev mob vascular.

Cov neeg mob noj tshuaj tau sau tseg tias nws cov txiaj ntsig thiab kev ntseeg tau, txawm hais tias tus nqi siab tsis ua rau nrov.

Liprimar: kev taw qhia rau kev siv

Cov tshuaj yog kws kho rau cov kab mob nram qab no:

• hypercholesterolemia,
• tag nrho cov hom hyperlipidemia,
• dibetalipoproteinemia,
• hypertriglyceridemia,
• cov pab pawg muaj kev pheej hmoo rau kev txhim kho tus mob plawv (cov neeg laus dua 55 xyoo, haus luam yeeb, cov neeg mob ntshav qab zib mellitus, mob muaj keeb tiv, ntshav siab thiab lwm tus),
• mob plawv plawv.

Koj tuaj yeem txo cov roj cholesterol, soj ntsuam kev noj zaub mov zoo, kev tawm dag zog, nrog kev rog dhau los ntawm kev tso cov roj hauv lub cev ntau dhau, yog tias cov yeeb yam no tsis muab cov txiaj ntsig, tso cov tshuaj uas txo cov roj cholesterol.

Nws yog ib qho tsim nyog kom ua raws li cov lus qhia rau kev siv Liprimar. Nws tsis muaj sij hawm txwv rau kev noj cov tshuaj. Raws li qhov ntsuas ntawm LDLP (cov roj (cholesterol) tsis zoo), cov tshuaj txhua hnub ntawm cov tshuaj (ib txwm) tau xam. Tus neeg mob nrog rau thawj daim ntawv ntawm hypercholesterolemia los yog sib xyaw ua ke hyperlipidemia yog tau txhaj 10 mg, noj txhua hnub rau 2-4 lub lis piam. Cov neeg mob uas tau los ntawm keeb kwm hypercholesterolemia raug kho ntau tshaj 80 mg.

Xaiv cov koob tshuaj uas cuam tshuam rau cov rog metabolism yuav tsum raug tswj los ntawm qib lipid hauv cov ntshav.

Nrog kev ceev faj, cov tshuaj yog tawm rau cov neeg mob uas lub siab tsis ua haujlwm lossis muaj kev sib xyaw nrog Cyclosparin (tsis ntau tshaj 10 mg rau ib hnub), muaj kev txom nyem los ntawm cov kab mob hauv lub raum, cov neeg mob uas muaj hnub nyoog txwv tsis tas yuav siv.

Kev Sib Sau thiab daim ntawv ntawm kev tso tawm

Muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj, hauv cov hlwv ntawm 7-10 tej daim, tus naj npawb ntawm cov hlwv hauv pob kuj tseem sib txawv, ntawm 2 txog 10. Cov khoom tseem ceeb yog calcium ntsev (atorvastatin) thiab cov tshuaj ntxiv: croscarmellose sodium, calcium carbonate, candelila wax, me cellulose muaju, hyprolose, lactose monohydrate, polysorbate-80, opadra dawb, magnesium stearate, simethicone emulsion.

Elliptical Liprimar ntsiav tshuaj coated nrog lub plhaub dawb, nyob ntawm seb qhov ntau npaum li cas hauv milligrams, muaj engraving ntawm 10, 20, 40 lossis 80.

Cov khoom tseem ceeb

Cov cuab yeej tseem ceeb ntawm Liprimar yog nws cov hypolipidemia. Cov tshuaj yaj yeeb pab txo qis zus tau cov cov enzymes ua lub luag haujlwm ntawm cov roj (cholesterol). Qhov no ua rau muaj kev txo qis hauv cov roj hauv cov ua haujlwm los ntawm lub siab, feem, nws cov qib hauv cov ntshav txo qis, thiab kev ua haujlwm ntawm cov hlab plawv tau zoo tuaj.

Cov tshuaj yog tawm rau cov neeg uas muaj hypercholesterolemia, kev noj zaub mov tsis zoo tshuaj thiab lwm cov tshuaj txo cov rog. Tom qab kawm tiav ntawm kev kho, cov qib roj cholesterol poob los ntawm 30-45%, thiab LDL - los ntawm 40-60%, thiab cov lej-lipoprotein hauv cov ntshav nce ntxiv.

Kev siv Liprimar pab txo kev txhim kho cov mob plawv los ntawm 15%, cov neeg tuag los ntawm kev mob plawv poob qis, thiab kev pheej hmoo ntawm lub plawv nres thiab muaj kev phom sij rau lub plawv nres tsawg dua 25%. Mutagenic thiab carcinogenic cov yam ntxwv tsis tau pom.

Phiv los ntawm Liprimara

Zoo li txhua yam tshuaj, qhov no muaj kev phiv. Rau Liprimar, cov lus qhia rau kev siv qhia tau tias nws feem ntau zoo rau ua.Txawm li cas los xij, ib tug xov tooj ntawm cov kev mob tshwm sim tau pom: insomnia, mob ntev nkees mob ntsws (asthenia), mob taub hau hauv plab, raws plab thiab dyspepsia, tsam plab (mob plab) thiab cem quav, myalgia, xeev siab.

Cov tsos mob ntawm tus mob anaphylaxis, anorexia, mob pob txaws, mob leeg thiab mob rwj, hypo- lossis hyperglycemia, kiv taub hau, daj ntseg, tawv nqaij tawm pob, khaus, urticaria, myopathy, tsis nco qab, poob qis los yog nce rhiab, neuropathy, pancreatitis, paug, ntuav yog tsis tshua pom. thrombocytopenia.

Cov kev mob tshwm sim los ntawm Liprimar, xws li kev o ntawm qhov sib txawv, kev rog, mob hauv siab, alopecia, tinnitus, thiab kev txhim kho ntawm cov pob zeb mob hauv lub raum tsis ua haujlwm, kuj tau pom.

Lus Tshaj Tawm

Atorvastatin - ib qho tshuaj ntawm Liprimar - yog ib hom tshuaj uas nrov tshaj plaws rau kev txo qis lipoproteins tsawg. Kev ntsuam xyuas los ntawm Grace thiab 4S tau qhia txog kev ua kom zoo dua ntawm atorvastatin dhau simvastatin hauv kev tiv thaiv kev txhim kho ntawm txoj kev xoom xaim kev noj qab haus huv thiab mob stroke. Hauv qab no peb xav txog cov tshuaj ntawm pawg statin.

Atorvastatin-raws li cov khoom lag luam

Cov lus sib piv Lavxias ntawm Liprimar, Atorvastatin, yog tsim los ntawm cov tuam txhab kws kho mob: Kanofarma Ntau lawm, ALSI Pharma, Vertex. Qhov ncauj ntsiav tshuaj nrog qhov ntau npaum ntawm 10, 20, 40 lossis 80 mg. Noj ib zaug ib hnub nyob rau tib lub sijhawm, tsis hais noj mov dabtsi.

Feem ntau cov neeg siv khoom nug lawv tus kheej - Atorvastatin lossis Liprimar - uas yog qhov zoo dua?

Cov nyhuv tshuaj ntawm "Atorvastatin" zoo ib yam li kev ua ntawm "Liprimar", vim tias cov tshuaj nyob rau hauv lub hauv paus muaj tib lub zog tshuaj. Cov txheej txheem ntawm kev ua ntawm thawj cov tshuaj yog tswj kom muaj kev cuam tshuam kev coj ua ntawm cov roj (cholesterol) thiab atherogenic lipoproteins los ntawm lub cev lub cev. Kev siv cov roj LDL hauv lub siab ua haujlwm nce siab, thiab tus nqi ntawm kev tsim tawm ntawm anti-atherogenic high-density lipoproteins kuj nce me ntsis.

Ua ntej kev teem sij hawm ntawm Atorvastatin, tus neeg mob tau kho kom haum rau kev noj zaub mov noj thiab teem ib chav muaj kev tawm dag zog, nws tshwm sim uas qhov no twb coj tau qhov txiaj ntsig zoo, tom qab ntawv kho cov statins yuav tsis tsim nyog.

Yog tias nws tsis tuaj yeem ua kom lub cev sawv cev hauv qib siab nrog cov tshuaj tsis yog siv tshuaj, cov tshuaj ntawm ib pawg loj ntawm cov tshuaj statins raug xaj, uas suav nrog Atorvastatin.

Thaum pib theem ntawm kev kho mob, Atorvastatin raug xaj 10 mg ib hnub ib zaug. Tom qab 3-4 lub lis piam, yog tias qhov tshuaj xaiv tau xaiv qhov raug, kev hloov ntawm lipid spectrum yuav pom tau. Hauv cov lipid profile, qhov kev txo qis ntawm cov roj (cholesterol) tag nrho raug sau tseg, qib qis lipoproteins tsawg tsawg thiab qhov qis, qhov qis ntawm triglycerides tsawg dua.

Yog hais tias theem ntawm cov tshuaj no tsis tau hloov lossis tseem nce ntxiv, nws yog qhov tsim nyog los kho qhov tshuaj ntawm Atorvastatin. Txij li cov tshuaj muaj nyob hauv ntau qhov ntau, nws yooj yim heev rau cov neeg mob hloov nws. 4 lub lis piam tom qab nce qhov koob tshuaj, lipid spectrum tsom xam yog rov ua dua, yog tias tsim nyog, qhov koob tshuaj tau nce dua, qhov siab tshaj plaws niaj hnub noj yog 80 mg.

Tus txheej txheem ntawm kev ua, kev haus tshuaj thiab kev mob tshwm sim ntawm Liprimar thiab nws cov neeg Lavxias yog tib yam. Qhov zoo ntawm Atorvastatin suav nrog nws cov nqi pheej yig dua. Raws li kev txheeb xyuas, cov tshuaj Lavxias feem ntau ua rau muaj kev phiv thiab ua xua piv nrog Liprimar. Thiab lwm qhov tsis txaus ntseeg yog kev kho mus sij hawm ntev.

Lwm yam kev hloov rau Liprimar

Atoris yog ib qho tshuaj noj ntawm Liprimar, yog ib lub tshuaj tsim los ntawm lub tuam txhab Slovenian Slovenian KRKA. Nws tseem yog hom tshuaj uas zoo sib xws hauv nws txoj haujlwm pharmacological rau Liprimaru. Atoris yog muaj nrog qhov ntau dua qhov tau muab ntau piv rau Liprimar. Qhov no tso cai rau tus kws kho mob laij cov tshuaj ntau dua, thiab tus neeg mob tau yooj yim noj tshuaj.

Atoris tsuas yog tib qho tshuaj feem ntau (Liprimara generic) uas tau dhau los ntau qhov kev sim tshuaj mob thiab tau ua pov thawj nws cov hauj lwm zoo.Cov neeg ua haujlwm pab dawb los ntawm ntau lub tebchaws tau koom nrog nws txoj kev kawm. Txoj kev tshawb no tau tshawb raws li cov chaw kho mob thiab cov tsev kho mob. Raws li kev tshawb fawb hauv 7000 cov kev kawm noj Atoris 10 mg rau 2 hlis, txo qis ntawm atherogenic thiab tag nrho cov cholesterol los ntawm 20-25% tau sau tseg. Qhov tshwm sim ntawm kev mob tshwm sim hauv Atoris yog tsawg heev.

Liptonorm yog ib lub tshuaj Lavxias uas normalizes metabolism hauv cov rog hauv lub cev. Cov tshuaj nquag hauv nws yog atorvastine, ib yam khoom muaj nrog hypolipidemic thiab hypocholesterolemic kev txiav txim siab. Liptonorm muaj qhov ntsuas zoo ib yam rau kev siv thiab haus nrog Liprimar, zoo li cov kev mob tshwm sim zoo sib xws.

Cov tshuaj muaj nyob rau hauv tsuas yog ob qhov tshuaj ntawm 10 thiab 20 mg. Qhov no ua rau nws tsis yooj yim rau kev siv los ntawm cov neeg mob kev txom nyem los ntawm cov ntaub ntawv tsis zoo ntawm atherosclerosis, heterozygous tsev neeg hypercholesterolemia, lawv yuav tsum noj 4-8 ntsiav tshuaj ib hnub, txij li kev siv tshuaj txhua hnub yog 80 mg.

Torvacard yog lub tshuaj yeeb yaj kiab uas nto moo tshaj plaws ntawm Liprimar. Ua cov chaw lag luam Slovak lub tuam txhab Zentiva. "Torvacard" tau tsim nws tus kheej kom zoo rau kev kho cov roj (cholesterol) hauv cov neeg mob kev txom nyem los ntawm cov kab mob plawv. Nws tau ua tiav yog siv los kho cov neeg mob nrog cerebrovascular thiab kev mob ntshav siab tsis txaus, nrog rau kev tiv thaiv ntawm cov teeb meem xws li mob stroke thiab lub plawv nres. Cov tshuaj ua rau txo qis ntawm cov triglycerides hauv cov ntshav. Nws tau ua tiav yog siv los kho cov mob muaj keeb ntawm dyslipidemia, piv txwv li, kom nce qib ntawm "pab" high-density lipoproteins.

Cov ntawv tso tawm ntawm "Torvokard" 10, 20 thiab 40 mg. Atherosclerosis txoj kev kho yog pib, feem ntau nrog 10 mg, tom qab tau kho theem ntawm triglycerides, roj cholesterol, lipoproteins uas tsis muaj ntau. Tom qab 2-4 lub lis piam nqa tawm kev tswj xyuas ntawm lipid spectrum. Nrog kev kho mob tsis ua haujlwm, ntxiv rau kev noj tshuaj. Qhov tshuaj ntau ntau rau ib hnub yog 80 mg.

Tsis zoo li Liprimar, Torvacard zoo dua rau cov neeg mob uas muaj cov kab mob ntawm cov hlab plawv, qhov no yog nws "+".

Rosuvastatin-based khoom

"Rosuvastatin" yog tus neeg sawv cev thib peb uas muaj cov roj lipid. Npaj tsim rau nws lub hauv paus yaj zoo nyob rau hauv cov kua ua kua ntawm cov ntshav. Lawv cov nyhuv tseem ceeb yog qhov txo qis ntawm tag nrho cov roj (cholesterol) thiab atherogenic lipoproteins. Lwm qhov taw tes zoo, "Rosuvastatin" yuav luag tsis muaj kev cuam tshuam ntawm daim siab mob thiab tsis ua rau cov leeg nqaij. Yog li no, statins raws li rosuvastatin tsis tshua muaj kev ua rau muaj teeb meem ntawm daim siab tsis ua hauj lwm, nce siab ntawm transaminases, myositis, thiab myalgia.

Lub ntsiab pharmacological kev ua yog tsom rau kev tsuj cov hluavtaws thiab nce ntxiv kev nthuav dav ntawm atherogenic feem ntawm cov rog. Cov txiaj ntsig ntawm kev kho mob tshwm sim nrawm dua nrog kev kho Atorvastatin, thawj cov txiaj ntsig tau pom los ntawm qhov kawg ntawm thawj lub lim tiam, cov txiaj ntsig siab tshaj plaws tuaj yeem pom ntawm 3-4 lub lis piam.

Cov tshuaj hauv qab no yog xyuas los ntawm rosuvastatin:

"Crestor" lossis "Liprimar" dab tsi los xaiv? Npaj yuav tsum tau xaiv los ntawm tus kws kho mob tuaj koom.

Simvastatin-based khoom

Lwm qhov nrov lipid-txo cov tshuaj yog Simvastatin. Raws li nws, ntau cov tshuaj tau tsim cov khoom siv tau zoo los kho tus mob atherosclerosis. Kev soj ntsuam sim tshuaj ntawm cov tshuaj no, uas tau ua ntau tshaj li tsib xyoos thiab muaj kev cuam tshuam nrog ntau tus neeg, pab txiav txim siab tias simvastatin-based tshuaj txo cov kev pheej hmoo ntawm lub plawv thiab mob hlab ntsha hauv cov neeg mob kev mob plawv thiab cerebrovascular.

Cov tshuaj ntawm Liprimar raws li simvastatin:

Ib qho kev txiav txim siab cuam tshuam rau kev yuav ib qho tshuaj tshwj xeeb yog tus nqi. Qhov no kuj siv rau cov tshuaj uas thim rov qab kev cuam tshuam ntawm cov rog metabolism.Kev kho cov mob zoo li no yog tsim los rau ntau lub hlis, thiab qee xyoo. Tus nqi rau cov tshuaj zoo ib yam hauv cov chaw muag tshuaj txawv ntawm cov tuam txhab muag tshuaj ntawm lub sijhawm vim tias cov nqi sib txawv ntawm cov cai ntawm cov tuam txhab no. Kev teem caij cov tshuaj thiab xaiv cov tshuaj yuav tsum tau nqa los ntawm tus kws kho mob, txawm li cas los xij, tus neeg mob muaj kev xaiv tshuaj los ntawm ib pawg pharmacological, uas sib txawv hauv cov chaw tsim khoom thiab tus nqi.

Tag nrho cov saum toj no hauv tsev thiab txawv teb chaws, Liprimar hloov chaw, tau dhau los hauv kev kuaj mob hauv tsev kho mob thiab tau tsim lawv tus kheej los ua cov neeg sawv cev uas ua haujlwm ntawm cov rog rog. Cov txiaj ntsig zoo nyob rau hauv daim ntawv ntawm cov roj tsawg dua tau pom nyob hauv 89% ntawm cov neeg mob hauv thawj lub hlis ntawm kev kho mob.

Kev txheeb xyuas txog Liprimar feem ntau yog qhov zoo. Cov tshuaj zoo txo ​​cov roj cholesterol, tiv thaiv kev pheej hmoo ntawm kev tsim cov hlab plawv cov nyom. Ntawm qhov tsis zoo - cov nqi siab thiab qhov tshwm sim. Ntawm cov analogues thiab cov generics, ntau yam zoo li Atoris. Nws ua lub cim rau Liprimar, kev xyaum tsis ua rau muaj kev tsis zoo ntawm lub cev.

Cov kev txheeb xyuas pom tseeb tias ntawm cov pheej yig-analogues, Lavxias Liptonorm yog qhov pom zoo. Muaj tseeb, nws qhov kev ua tau phem dua li ntawm Liprimar.

Atoris thiab Hla

Nyob zoo Tav Kuv tau noj Atoris, 20 mg rau ob lub lis piam. Kuv txais rau hmo ntuj. Lub lim tiam dhau los, npau suav phem pib ua rau nce siab. Dua li kev noj cov tshuaj no, Kuv tsis tuaj yeem txuas tus npau suav phem nrog txhua yam. Koj tsis tuaj yeem tsis lees txais. Puas yog nws tau mus rau ntawm tus ntoo khaub lig, (muaj npau suav phem los ntawm nws), Atoris puas yuav pab nws haus dej, tab sis thaum sawv ntxov? Dab tsi tuaj yeem ua tau ntawm qhov no? Ua tsaug rau koj!

Nyob zoo Mila, hmoov tsis, npau suav phem yog kev mob tshwm sim (tsis tshua muaj heev, los ntawm txoj kev), yam ntxwv ntawm ntau yam statins. Ntawm txhua yam statins, tsawg tshaj plaws lipophilicity, thiab yog li muaj peev xwm nkag mus rau lub hlwb, cuam tshuam kev hloov pauv ntawm serotonin nyob ntawd thiab ua rau insomnia thiab / lossis npau suav phem, muaj rosuvastatin (aka Krestor). Hauv qhov no, qhov ntxim nyiam tias Krestor yuav ua rau koj npau suav phem yog tsawg dua, tab sis tsis sib npaug nrog xoom. Alas. Haus cawv atoris thaum sawv ntxov yog qhov tsis muaj tseeb, nws yuav tsis cuam tshuam qhov npau suav phem. Los ntawm txoj kev, nws yog qhov zoo dua rau haus statins nyob ib ncig ntawm 20.00, thaum kev ua si ntawm cov enzyme uas lawv cuam tshuam rau ntau tshaj plaws hauv lub cev. Yog tias tus npau suav phem txuas ntxiv, sab laj koj tus kws kho plawv txog kev hloov hauv chav kawm ntawm cov tshuaj kom txo qis roj.

Qoob loo.

Txhua qhov kev siv khoom raug tso cai tsuas yog kev sau ntawv pom zoo los ntawm tus tshaj tawm.