Amoxiclav Quicktab

Nyob rau hauv muaj pes tsawg leeg ntsiav tshuaj 250 mg / 125 mg lub Cheebtsam nrog amoxicillin (daim ntawv ntawm trihydrate) thiab clavulanic acid (potassium ntsev daim ntawv). Cov ntsiav tshuaj kuj tseem muaj tus pabcuam: MCC sodium croscarmellose.

Amoxiclav ntsiav tshuaj 2X 625 mg thiab 1000 mg muaj lub ntsiab lus amoxicillin thiab clavulanic acid, ntxiv rau cov khoom siv ntxiv: anhydrous colloidal silicon dioxide, flavors, aspartame, daj hlau oxide, talc, roj nplua nyeem roj, MCC silicate.

Tsim ntawm ntsiav tshuaj Amoxiclav Quicktab 500 mg thiab 875 mg muaj cov khoom xyaw nquag amoxicillin thiab clavulanic acid, ntxiv rau cov khoom siv ntxiv: anhydrous colloidal silicon dioxide, flavings, aspartame, daj hlau oxide, talc, hydrogen castor roj, MCC silicate.

Tsim ntawm cov hmoov los ntawm qhov kev ncua ntawv yog npaj Amoxiclavkuj tseem muaj amoxicillin thiab clavulanic acid, thiab kuj yog cov khoom siv tsis muaj zog suav nrog sodium citrate, MCC, sodium benzoate, mannitol, sodium saccharin.

Tsim ntawm hmoov rau qhov kev npaj infusion Amoxiclav iv muaj amoxicillin thiab clavulanic acid.

Daim ntawv tso tawm

Cov tshuaj yog nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj. Amoxiclav 250 mg / 125 mg - cov ntsiav tshuaj xim, pob muaj 15 pcs.

Amoxiclav 2X (500 mg / 125 mg, 875 mg / 125 mg) - ntsiav tshuaj, uas tau coated, tej zaum yuav muaj 10 lossis 14 pcs.

Amoxiclav Quicktab (500 mg / 125 mg, 875 mg / 125 mg) muaj nyob hauv daim ntawv ntawm cov ntsiav tshuaj tawg, hauv pob ntawv - 10 xws li cov ntsiav tshuaj.

Tsis tas li, cov khoom lag luam yog tsim los ntawm cov hmoov uas qhov kev rho tawm tau ua; lub raj mis muaj cov hmoov ntim rau kev npaj 100 ml ntawm cov khoom.

Hmoov kuj tsim tawm, los ntawm cov tshuaj uas tau tsim, uas tau tswj kav dej kom tiav. Lub raj mis muaj 600 mg ntawm cov tshuaj (amoxicillin 500 mg, clavulanic acid 100 mg), 1.2 g lub raj mis tseem muaj (amoxicillin 1000 mg, clavulanic acid 200 mg), 5 fl.

Pharmacological kev txiav txim

Cov Lus qhia muab cov ntaub ntawv uas tshuaj tua kab mob Amoxiclav (INN Amoksiklav) yog ib tus neeg sawv cev dav dav. Tshuaj tua kab mob pab pawg: qhov dav-spectrum penicillins. Cov tshuaj sib xyaw ua ke muaj cov tshuaj amoxicillin (penicillin ib nrab hluavtaws) thiab clavulanic acid (β-lactamase inhibitor). Muaj cov clavulanic acid nyob rau hauv kev npaj ua tiav kom muaj kev tawm tsam ntawm amoxicillin rau kev ua ntawm β-lactamases, uas yog tsim los ntawm cov kab mob me me.

Cov qauv ntawm clavulanic acid zoo ib yam li cov tshuaj tua kab mob beta-lactam, cov tshuaj yeeb tshuaj no tseem muaj cov nyhuv tua tshuaj. Amoxiclav tawm tsam tawm tsam cov kab mob uas nthuav tawm rhiab heev rau amoxicillin. Nov yog kab kab mob gram-zoo, aerobic gram-cov kab mob tsis zoo, gram-zoo thiab gram-negative anaerobes.

Pharmacokinetics thiab cov chaw muag tshuaj

Raws li phau ntawv qhia kev siv tshuaj Vidal, tom qab kev tswj hwm ntawm qhov ncauj ob qho tshuaj lom tawm ntawm lub plab zom mov, kev nqus ntawm cov khoom tsis cuam tshuam los ntawm kev noj zaub mov, yog li nws tsis muaj teeb meem yuav noj nws li cas ua ntej lossis tom qab noj mov. Kev siab tshaj plaws hauv ntshav pom ib teev tom qab siv tshuaj. Ob lub tshuaj ua haujlwm nquag ntawm cov tshuaj tau muab faib rau hauv dej thiab cov ntaub so ntswg. Amoxicillin tseem nkag mus rau hauv lub siab, kua dej synovial, prostate, tonsils, gall zais zis, cov leeg nqaij, qaub ncaug, lub ntsej muag tawm.

Yog tias daim nyias nyias ntawm lub paj hlwb tsis kub, ob qho khoom ua ke tsis nqus los ntawm BBB. Nyob rau tib lub sijhawm, cov cuab yeej ua kom zoo siab hla tus txheej txheem placental, lawv cov khoom siv yog txiav txim siab hauv niam mis. Lawv khi rau cov ntshav cov ntshav kom tsawg li tsawg tau.

Hauv lub cev, amoxicillin yauv nyob ib nrab metabolism hauv, clavulanic acid yog metabolized sib zog. Nws raug tawm hauv lub cev los ntawm lub raum, cov khoom me me ntawm cov tshuaj ua haujlwm uas ua rau sab nrauv yog txoj hnyuv thiab lub ntsws. Ib nrab-lub neej ntawm amoxicillin thiab clavulanic acid yog 1-1.5 teev.

Kev taw qhia txog kev siv Amoxiclav

Amoxiclav raug samfwm rau kev kis kabmob thiab mob kis kabmob vim tias muaj kev cuam tshuam ntawm cov tsiaj mob me me rau cov tshuaj no. Qhov taw qhia hauv qab no rau kev siv cov tshuaj no tau txiav txim siab:

• kis kab mob ntawm ENT plab hnyuv siab raum, nrog rau cov kab mob sib kis ntawm cov pa ntawm sab saud (otitis mediapharyngeal rwj, mob hlab ntsws, pharyngitistonsillitis)
• mob txeeb zig (nrog cystitisntawm prostate lwm yam)
• cov kab mob sib kis ntawm cov pa hauv txoj hlab ntsws qis (mob ntsws, mob ntswsmob thiab mob raum)
• gynecological kab mob ntawm kev kis tus kab mob,
• kis kab mob ntawm cov kab mob sib txuas thiab pob txha,
• kis kab mob ntawm cov nqaij mos, tawv nqaij (nrog rau qhov tshwm sim ntawm kev tom),
• biliary huam mob (cholangitis, cholecystitis),
• odontogenic tau tus kab mob.

Dab tsi ntxiv pab Amoxiclav, koj yuav tsum nug tus kws kho mob tshwj xeeb rau kev sab laj tus kheej.

Cov Yuav Tsum Muaj

Kev txiav txim siab vim li cas tshuaj ntsuab thiab lwm cov kev pab cuam ntawm cov tshuaj, ib qho kuj yuav tsum coj mus rau hauv tus account contraindications uas twb muaj lawm:

• mononucleosis mob sib kis,
• kab mob siab yav dhau los lossis mob siab daj ntseg thaum noj clavulanic acid lossis amoxicillin,
• lymphocytic leukemia,
• siab rhiab heev rau cov tshuaj tua kab mob los ntawm pab pawg ntawm cephalosporins, penicillins, thiab lwm yam tshuaj tua kab mob beta-lactam,
• siab rhiab heev rau cov nquag tshuaj ntawm cov tshuaj.

Nws ua tib zoo tshuaj rau cov neeg muaj kab mob siab, cov neeg muaj mob raum.

Sab sij huam

Thaum noj cov tshuaj tiv thaiv no, cov kev mob tshwm sim hauv qab no tuaj yeem tshwm sim hauv cov neeg mob:

• Lub plab zom mov: tsis zoo qab losntuav, xeev siab zawv plab, muaj qee zaus, kev mob tshwm sim ntawm kev mob plab, mob siab yog ua tau, ib qho kev qhia paub yog kab mob siab, mob daj ntseg, pseudomembranous mob plab.
• Hematopoietic system: Muaj qee zaus, thim rov qab muaj leukopenia, thrombocytopenia, feem ntau tsis tshua mob - eosinophilia, pancytopenia.
• Ua xua qhov tshwm sim: khauserythematous pob urticaria, muaj qee zaus - anaphylactic poob siabexudative erythema, o tuaj, kev tsis haum tshuaj vasculitis, ua rau pom ib leeg - Stevens-Johnson syndrome, pustulosis, exfoliative dermatitis.
• Kev khiav dej num muaj zog: kiv taub hau, mob taub hau, tsis tshua muaj tshwm sim - pom tshwm sim, qhov kev xav ntawm qhov ntxhov siab, hyperactivity, insomnia.
• Cov kab mob zis: crystalluria, interstitial nephritis.
• Muaj qee zaus, kev nrhiav tau superinfection yuav tshwm sim.

Nws tau sau tseg tias xws li kev kho mob, raws li txoj cai, tsis ua rau tawm kev cuam tshuam txog kev phiv.

Cov lus qhia rau kev siv Amoxiclav (Txoj kev thiab noj tshuaj ntawm Amoxiclav rau cov neeg laus)

Cov tshuaj hauv cov tshuaj tsis yog rau cov menyuam yaus hnub nyoog qis dua 12 xyoos. Thaum muab tshuaj rau, nws yuav tsum tau yug los rau hauv lub siab tias qhov kev tso cai noj tshuaj ib hnub ntawm clavulanic acid yog 600 mg (rau cov neeg laus) thiab 10 mg rau 1 kg ntawm qhov hnyav (rau menyuam yaus). Kev tso cai noj tshuaj txhua hnub ntawm amoxicillin yog 6 g rau cov neeg laus thiab 45 mg rau 1 kg ntawm qhov hnyav rau ib tus menyuam.

Kev ua niam txiv npaj tau yog npaj los ntawm kev zom cov ntsiab lus ntawm lub thauv hauv dej rau kev txhaj tshuaj. Txhawm rau kom yaj 600 mg ntawm cov tshuaj, koj xav tau 10 moles ntawm dej, kom yaj 1.2 g ntawm cov tshuaj - 20 ml dej. Kev daws yuav tsum tau maj mam muab rau li 3-4 feeb. Txoj kev lis ntshav ntawm lub plab yuav tsum txuas ntxiv rau 30-40 feeb. Tsis txhob muab cia rau cov tshuaj.

Ua ntej tshuaj loog rau kev tiv thaiv cov teeb meem purulent, koj yuav tsum nkag mus rau hauv txoj leeg 1.2 g ntawm tshuaj. Yog tias muaj kev pheej hmoo ntawm cov teeb meem tshwm sim, cov tshuaj no tau muab tso quav lossis tau txais qhov ncauj ntawm lub sijhawm tom qab kev phais mob. Lub sijhawm sijhawm ntawm kev pub nkag yog txiav txim los ntawm tus kws khomob.

Amoxiclav ntsiav tshuaj, cov lus qhia rau kev siv

Raws li txoj cai, cov neeg laus thiab menyuam yaus (uas hnyav tshaj 40 kg) tau txais 1 ntsiav tshuaj txhua yim teev. (375 mg), muab hais tias tus kab mob yog mob sib khuav lossis mob pesnrab. Lwm txoj kev kho mob uas tsim nyog nyob rau hauv cov ntaub ntawv no yog 1 ntsiav tshuaj txhua 12 teev. (500 mg + 125 mg). Txog rau cov mob hnyav, nrog rau kev kis mob ntawm lub ntsws ua pa, 1 ntsiav tshuaj tau qhia txhua yim teev. (500 mg + 125 mg) lossis noj txhua 12 teev 1 ntsiav tshuaj. (875 mg + 125 mg). Nyob ntawm tus kab mob, koj yuav tsum tau noj tshuaj tiv thaiv kab mob rau tsib mus rau kaum plaub hnub, tab sis tus kws kho mob yuav tsum tau sau ib qho zuj zus los siv tshuaj kho mob.

Rau cov neeg mob uas muaj tus mob odontogenic, qhia cov tshuaj txhua 8 teev, 1 ntsiav tshuaj. (250 mg + 125 mg) lossis ib zaug 12 teev, 1 ntsiav tshuaj txhua. (500 mg + 125 mg) rau tsib hnub.

Cov neeg muaj ntsis lub raum tsis ua hauj lwm, pom qhov txais tos ntawm 1 rooj. (500 mg + 125 mg) txhua kaum ob teev. Kev mob raum tsis zoo yog qhov ua rau muaj qhov ncua sij hawm ntau ntxiv txog li 24 xuab moos.

Kev Raug Ncaj Qiv Amoxiclav, lus qhia rau kev siv

Cov menyuam yaus lub hnub nyoog ntawm tus neeg mob muab rau qhov muab xam los ntawm qhov ntsuas qhov hnyav ntawm tus menyuam. Ua ntej npaj cov kua dej, koj yuav tsum co lub raj mis kom zoo. Hauv ob lub koob tshuaj, 86 ml dej yuav tsum tau ntxiv rau hauv lub raj mis, txhua zaus koj yuav tsum tau co nws cov ntsiab lus zoo. Nws yuav tsum raug sau tseg tias ib rab diav ntsuas muaj 5 ml ntawm qhov khoom. Muab rau ib koob tshuaj nyob ntawm seb nws muaj hnub nyoog thiab hnyav.

Cov lus qhia rau siv Amoxiclav rau menyuam yaus

Txij thaum yug mus txog peb lub hlis, cov menyuam raug xaj tshuaj nyob rau ntawm 30 mg rau 1 kg ntawm qhov hnyav (koob tshuaj ib hnub), cov koob tshuaj no yuav tsum tau muab faib sib npaug thiab muab sijhawm nrog ib zaug. Txij li hnub nyoog muaj peb hlis, Amoxiclav raug tshuaj ntawm 25 mg rau 1 kg ntawm qhov hnyav, nws zoo ib yam li muab faib sib npaug rau ob koob. Yog tias muaj cov kab mob sib kis ntawm cov mob hnyav, qhov koob tshuaj tau hais tawm ntawm qhov nqi ntawm 20 mg rau 1 kg ntawm qhov hnyav, nws tau muab faib ua peb txoj kev tswj hwm. Hauv cov kab mob sib kis hnyav, koob tshuaj yog tawm ntawm tus nqi ntawm 45 mg rau 1 kg ntawm qhov hnyav, faib nws faib ua ob zaug ib hnub.

Cov Tshuaj Hauv Tshuaj

Tus txheej txheem ntawm kev txiav txim ntawm Amoxiclav Quiktab yog vim muaj kev sib txuam ntawm cov haujlwm tseem ceeb hauv nws cov muaj pes tsawg leeg:

• amoxicillin yog qhov tshuaj tiv thaiv kab mob sab nrauv uas muaj kev tiv thaiv ntau yam kab mob gram-positive thiab gram-negative, vim nws qhov ua rau muaj kev puas tsuaj los ntawm l-lactamases, cov kev ua haujlwm ntawm amoxicillin tsuas yog txwv rau cov kab mob me me uas ua cov enzyme no,
• clavulanic acid, a β-lactamase inhibitor yam ntxwv ntawm penicillins, inactivating ntau ntawm cephalosporins thiab penicillins tiv β-lactamases pom hauv microorganisms, zoo heev tiv thaiv plasmid β-lactamases, uas feem ntau ua rau muaj kev tiv thaiv kab mob, tab sis tsis muaj txiaj ntsig tiv thaiv cov chromosomal β-lactamases. hom. Lub xub ntiag ntawm clavulanic acid nyob rau hauv kev npaj tiv thaiv amoxicillin los ntawm kev puas tsuaj los ntawm β-lactamases, cia nws nthuav nws cov antibacterial spectrum.

Amoxicillin xyaw nrog clavulanic acid yog tawm tsam kev tawm tsam cov kab mob microflora hauv qab no:

• Gram-positive aerobic microorganisms: Streptococcus pneumoniae, Streptococcus viridans, Streptococcus pyogenes, Enterococcus spp., Streptococcus bovis, Staphylococcus epidermidis (tshwj tsis yog kab mob tiv thaiv kab mob methicillin), Staphylococcus aureus, Staphy.
• Gram-negative aerobic microorganisms: Brucella spp., Bordetella pertussis, Campylobacter jejuni, Gardnerella vaginalis, Escherichia coli, Haemophilus ducreyi, Helicobacter pylori, Haemophilus spp. spp., Salmonella spp., Yersinia enterocolitica, Vibrio cholerae, Eikenella corrodens,
• Gram-positive anaerobic microorganisms: Actinomyces israelii, Peptostreptococcus spp., Peptococcus spp., Clostridium spp., Prevotella spp., Fusobacterium spp.,
• Gram-negative anaerobic microorganisms: Bacteroides spp.

Cov lus qhia rau siv Amoxiclav Quicktab: txoj kev thiab ntau npaum li cas

Amoxiclav Quiktab ntsiav tshuaj noj ntawm qhov ncauj, yav dhau los yaj hauv 1 /₂ tsom iav dej (tsawg kawg 30 ml) thiab sib tov kom huv. Koj tuaj yeem tuav cov ntsiav tshuaj hauv koj lub qhov ncauj kom txog thaum yaj tag, thiab tom qab ntawd nqos nws.

Nws raug nquahu kom noj cov tshuaj tam sim ua ntej noj mov kom txo qhov kev phiv ntawm tus mob plab zom zaub mov.

Cov tshuaj pom zoo rau cov neeg laus thiab cov menyuam yaus hnub nyoog 12 xyoos (nrog lub cev hnyav dua 40 kg):

• mob me los sis mob sib kis: 1 ntsiav tshuaj ntawm Amoxiclav Quiktab 500 + 125 mg txhua 12 teev,
• raug mob hnyav thiab mob ntsws ua rau puas tsuaj: 1 ntsiav tshuaj ntawm Amoxiclav Quicktab 875 + 125 mg txhua 12 teev lossis 1 ntsiav tshuaj ntawm Amoxiclav Quicktab 500 + 125 mg txhua 8 teev.

Lub sijhawm kho yog txog li 2 asthiv.

Yog tias txoj kev kho mob pib nrog kev tswj hwm ntawm amoxicillin thiab clavulanic acid, tom qab ntawd nws tuaj yeem hloov mus rau kev noj Amoxiclav Quiktab ntsiav tshuaj sab hauv.

Noj ntau dhau

Cov ntaub ntawv hais txog kev phom sij txog lub neej lossis kev tuag vim qhov kev noj ntau tshaj ntawm Amoxiclav Quicktab tsis tau sau cia.

Cov tsos mob ntawm kev siv ntau tshaj yog kev cuam tshuam ntawm txoj hnyuv: mob plab, mob plab / ntuav, insomnia, ntxhov siab vim arousal, kiv taub hau kuj ua tau, qee qhov teeb meem - chua leeg.

Kev kho mob kom zoo yog raug tshuaj, tom qab siv cov kev ntsuas (nrog kev tswj hwm ntawm cov ntsiav tshuaj, tsis pub ntau tshaj 4 teev) kom txo qis qhov nqus ntawm cov tshuaj - pais plab lav thiab siv cov pa hluav taws. Amoxicillin thiab clavulanic acid tau muab tshem tawm thaum lub sijhawm hemodialysis. Tus neeg mob yuav tsum muaj kev saib xyuas mob.

Thaum txo qis ntshav siab, tus neeg mob yuav tsum tuav txoj haujlwm ntawm Trendelenburg - pw ntawm koj sab nraub qaum, tsa lub plab mog hauv qhov sib piv rau lub taub hau ntawm kaum ntawm 45 °.

Cov lus qhia tshwj xeeb

Hauv chav kawm ntawm kev kho mob, tswj kev ua haujlwm ntawm daim siab, lub raum thiab hematopoiesis yog qhov yuav tsum tau ua.

Thaum lub raum tsis zoo, yuav tsum tau txhaj tshuaj ntau dua lossis nce ntxiv nruab nrab ntawm nws cov koob tshuaj yog qhov tsim nyog.

Thaum lub sijhawm kho nrog Amoxiclav Quicktab, qhov kev tsis tseeb - qhov tsis zoo yog qhov tshwm sim vim kev siv Benedict reagent lossis Felling tov los txiav txim siab txog qib ntawm cov piam thaj hauv cov zis, yog li ntawd, cov tshuaj tiv thaiv enzymatic nrog glucosidase raug pom zoo.

Thaum tsis ua haujlwm lub raum

Amoxiclav Kviktab koob tshuaj tau hloov kho hauv cov lus qhia ntawm kev txo qis cov koob tshuaj lossis nce lub sij hawm nruab nrab ntawm cov koob tshuaj raws li qhov mob hnyav ntawm lub raum tsis ua haujlwm:

• mob raum tsis ua hauj lwm nrog creatinine tshem tawm (CC) los ntawm 10 txog 30 ml / min: 1 ntsiav tshuaj (500 + 125 mg) txhua 12 teev,
• mob raum tsis zoo nrog CC tsawg dua 10 ml / min: 1 ntsiav tshuaj (500 + 125 mg) txhua 24 teev.

Hauv anuria, qhov luv nruab nrab ntawm cov koob tshuaj yuav tsum nce ntxiv mus rau 48 teev lossis ntau dua.

Ceev faj pom zoo rau cov neeg mob uas muaj mob raum ua tsis tau zoo thaum noj cov tshuaj.

Yeeb tshuaj sib cuam tshuam

• antacids, glucosamine, laxatives, aminoglycosides: qeeb ntawm kev nqus ntawm Amoxiclav Quicktab,
• ascorbic acid: ua rau kom nqus ntawm amoxicillin thiab clavulanic acid,
• diuretics, allopurinol, phenylbutazone, non-steroidal anti-inflammatory tshuaj (NSAIDs), lwm yam tshuaj, tubular secretion blockers: ua rau kom muaj kev cia siab ntawm amoxicillin, tab sis tsis cuam tshuam rau theem ntawm clavulanic acid, vim nws yog tsuas yog los ntawm glomerular filtration,
• methotrexate: Amoxiclav Quicktab txhawb nws txoj kev lom,
• allopurinol: cov tshuaj tsub kom qhov tshwm sim ntawm exanthema,
• disulfiram: zam kev tswj hwm nrog Amoxiclav Quiktab,
• cov tshuaj tiv thaiv anticoagulant: txij li Amoxiclav Quiktab tuaj yeem qee qhov ntev ntawm lub sijhawm prothrombin, kev ceev faj yuav tsum siv thaum siv ib txhij,
• rifampicin: yog qhov kev tawm tsam ntawm amoxicillin nrog rau kev sib xyaw ua kom tsis muaj zog tiv thaiv kab mob,
• cov tshuaj tua kab mob bacteriostatic (macrolides, tetracyclines), sulfonamides: Amoxiclav Quiktab yuav tsum siv ob peb teev ua ntej lawv noj,
• probenecid: inhibits qhov kev tawm ntawm amoxicillin, ua rau kom nws cov kev nkag siab,
• tshuaj tiv thaiv qhov ncauj: Amoxiclav Quicktab txo lawv txoj kev ua tau zoo.

Amoxiclav Quiktab analogues suav nrog Amoxivan, Amovicomb, Amoxicillin + Clavulanic acid, Amoxiclav, Arlet, Augmentin, Betaclav, Bactoclav, Verclav, Medoclav, Clamosar, Novaclav, Panclav 2X, Rapiclav, Ranklav, Flemoclav Soloktab, Drib.

Amoxiclav Quiktab tshuaj xyuas

Raws li kev txheeb xyuas, Amoxiclav Quicktab yog cov tshuaj tiv thaiv zoo uas pab nrog ntau yam kab mob. Feem ntau cov neeg mob nyiam qhov saj ntawm cov ntsiav tshuaj ploj thiab tsuas yog qee tus hu nws tsis kaj siab. Txoj kev muaj peev xwm ntawm kev siv cov tshuaj thaum cev xeeb tub thiab thaum pub mis niam yog sau tseg tias muaj txiaj ntsig zoo. Kev qhia tshwj xeeb hauv kev txheeb xyuas tau muab rau qhov tseem ceeb ntawm cov lus qhia kho mob thaum noj tshuaj.

Feem ntau ntawm cov neeg mob ib txwm suav cov nqi ntawm cov tshuaj yuav yog qhov tseem ceeb drawback.

Amoxiclav ntsiav tshuaj thiab hmoov - cov lus qhia rau siv

Rau cov menyuam hnub nyoog qis dua 12 xyoos - 40 mg rau ib phaus ntawm qhov hnyav ib hnub.
Rau cov menyuam yaus uas lub cev hnyav dua 40 kg, cov tshuaj tau sau tseg ua tus laus.

Cov neeg laus tau tshuaj: 375 mg ntsiav tshuaj tau noj txhua 8 teev nyob rau ib hnub, 625 mg ntsiav tshuaj txhua 12 teev. Thaum kws kho mob muab tshuaj rau kho cov mob hnyav, cov koob tshuaj 625 mg txhua 8 teev, lossis 1000 mg txhua 12 teev, raug siv.

Nws yuav tsum raug sau tseg tias cov ntsiav tshuaj kuj yuav txawv ntawm qhov tsis muaj qhov sib piv ntawm cov tshuaj nquag. Yog li, koj tsis tuaj yeem hloov lub ntsiav tshuaj 625 mg (500 g ntawm amoxicillin thiab 125 g ntawm clavulanic acid) nrog ob 375 mg ntsiav tshuaj (250 g ntawm amoxicillin thiab 125 g ntawm clavulanic acid).

Cov qauv hauv qab no yog siv los kho tus kab mob odontogenic. 375 mg ntsiav tshuaj tau noj txhua 8 teev, puag ncig lub moos. 625 mg ntsiav tshuaj tom qab 12 teev.

Yog tias tsim nyog, kev siv tshuaj kho mob rau kev kho mob rau cov neeg mob raum yuav tsum coj mus rau hauv tus account creatinine nyob rau hauv cov zis. Cov neeg mob mob siab yuav tsum tau soj ntsuam tas li ntawm lawv txoj haujlwm.

Hmoov rau kev ncua rau cov menyuam mos thiab menyuam yaus txog li 3 hlisCov. Kev muab tshuaj yog nqa tawm siv cov raj ntsuas tshwj xeeb lossis rab diav. Tsuas tshuaj - 30 mg ntawm amoxicillin rau ib phaus ntawm qhov hnyav, ob zaug ib hnub.

Rau cov menyuam yaus hnub nyoog ntau dua peb lub hlis rau kev kis mob me thiab mob nyhav - 20 mg / kg ntawm lub cev qhov hnyav, thiab rau kis hnyav - 40 mg / kg. Qhov tshuaj thib ob kuj tseem siv rau hauv kev kho mob ntawm kev sib sib zog nqus - mob ntawm pob ntseg hauv nruab nrab, mob siab, ntsws, mob ntsws. Ib qho kev qhia tau txuas rau cov tshuaj no, nyob rau hauv uas muaj cov ntxhuav tshwj xeeb uas tso cai rau koj kom laij cov tshuaj xav tau ntawm cov tshuaj rau cov menyuam yaus.

Qhov siab tshaj plaws tau tso cai noj tshuaj txhua hnub ntawm amoxicillin rau cov menyuam yaus yog 45 mg / kg ntawm qhov hnyav, rau cov laus - 6 grams. Clavulanic acid tuaj yeem noj nyob rau ib hnub tsis pub ntau tshaj 600 mg rau cov neeg laus thiab 10 mg / kg rau menyuam yaus.

Dosage daim ntawv

Zaj duab xis-cov ntsiav tshuaj 500 mg / 125 mg, 875 mg / 125 mg

Muaj ib txheej ntim yeeb yaj kiab-ntim

yam tshuaj: amoxicillin (li amoxicillin trihydrate) 500 mg thiab clavulanic acid (li potassium clavulanate) 125 mg (rau tshuaj 500 mg / 125 mg) lossis amoxicillin (li amoxicillin trihydrate) 875 mg thiab clavulanic acid (raws li potassium clavulanate) 125 mg (rau cov tshuaj ntau npaum 875 mg / 125 mg).

tus zam: colloidal silicon dioxide, crospovidone anhydrous, sodium carboxymethyl cellulose, magnesium stearate, qhuav microcrystalline cellulose.

zaj duab xis txheej muaj pes tsawg leeg: hydroxypropyl cellulose, ethyl cellulose, polysorbate, triethyl citrate, titanium dioxide (E 171), talc.

Cov ntsiav tshuaj yog coated nrog zaj duab xis daim nyias nyias ntawm cov xim dawb lossis yuav luag xim dawb, oblong, nrog ib tug bevel, sau nrog "875/125" thiab ib qho cim ntawm ib sab, thiab sau nrog "AMS" nyob rau sab nraud (rau ntau npaum ntawm 875 mg / 125 mg).

Farmacotherapeutic pab pawg

Cov tshuaj tua kab mob rau kev siv system. Tshuaj Beta-lactam tshuaj tua kab mob - Penicillins. Penicillins txuam nrog beta-lactamase inhibitors. Clavulanic acid + amoxicillin.

ATX Code J01CR02

Cov chaw muag tshuaj

Cov Tshuaj Pharmacokinetics

Amoxicillin thiab clavulanic acid yog ua kom yaj tag rau hauv kev daws teeb meem ntawm lub cev pH qhov tseem ceeb ntawm lub cev. Ob qho khoom siv tau zoo nqus tom qab kev tswj hwm ntawm qhov ncauj. Nws yog qhov zoo dua rau noj amoxicillin / clavulanic acid lub sijhawm lossis thaum pib noj mov. Tom qab kev tswj hwm ntawm qhov ncauj, lub bioavailability ntawm amoxicillin thiab clavulanic acid yog kwv yees li 70%. Lub zog puab ntawm kev saib xyuas ntawm cov tshuaj nyob rau hauv lub plasma ntawm ob feem sib xyaw zoo ib yam nkaus. Qhov siab tshaj tawm cov dej siab tau mus txog 1 teev tom qab kev tswj hwm.

Qhov ntau ntawm amoxicillin thiab clavulanic acid nyob rau hauv cov ntshav ntshav thaum noj cov tshuaj amoxicillin / clavulanic acid npaj tau zoo ib yam li qhov tau pom nrog cais lub qhov ncauj ntawm kev tswj hwm sib npaug ntawm amoxicillin thiab clavulanic acid.

Txog 25% ntawm tag nrho cov nyiaj ntawm clavulanic acid thiab 18% ntawm amoxicillin khi rau cov ntshav protein. Qhov ntim ntawm kev faib tawm rau kev tswj hwm qhov ncauj ntawm cov tshuaj yog kwv yees 0.3-0.4 l / kg ntawm amoxicillin thiab 0.2 l / kg ntawm clavulanic acid.

Tom qab kev tswj hwm kev siv tshuaj, ob qho tib si amoxicillin thiab clavulanic acid tau pom nyob hauv lub zais zis, fiber ntawm lub plab plab, tawv nqaij, rog, cov leeg nqaij, synovial thiab peritoneal kua, bile thiab pus. Amoxicillin nkag mus rau hauv lub cev tsis zoo ua kua dej.

Amoxicillin thiab clavulanic acid hla qhov chaw tiv thaiv hniav. Ob seem puav leej sib kis mus rau niam mis.

Amoxicillin yog qee cov tso tawm hauv cov zis hauv daim ntawv ntawm tsis muaj zog penicillic acid hauv qhov sib npaug ntawm 10-25% ntawm thawj koob tshuaj. Clavulanic acid yog metabolized nyob rau hauv lub cev thiab nthuav tawm hauv cov zis thiab quav, ntxiv rau hauv cov qauv ntawm cov pa roj carbon dioxide nrog cov pa tawm ntawm huab cua.

Qhov nruab nrab kev tshem tawm ib nrab-lub neej ntawm amoxicillin / clavulanic acid yog li 1 teev, thiab qhov nruab nrab tag nrho kev sib tw yog kwv yees li 25 l / teev. Li ntawm 60-70% ntawm amoxicillin thiab 40-65% ntawm clavulanic acid raug tso tawm tsis hloov pauv hauv cov zis thaum thawj 6 teev tom qab noj ib qho tshuaj amoxicillin / clavulanic acid ntsiav tshuaj. Thaum lub sij hawm ntau cov kev tshawb fawb, nws tau pom tias 50-85% ntawm amoxicillin thiab 27-60% ntawm clavulanic acid tau tawm hauv cov zis hauv 24 teev. Qhov loj tshaj plaws ntawm clavulanic acid tau tawm hauv thawj 2 teev tom qab daim ntawv thov.

Kev siv ib txhij ntawm probenecid qeeb ua rau kev tso tawm ntawm amoxicillin, tab sis cov tshuaj no tsis cuam tshuam qhov cuam tshuam ntawm clavulanic acid los ntawm ob lub raum.

Ib nrab-lub neej ntawm amoxicillin zoo ib yam li cov menyuam yaus hnub nyoog 3 hlis txog 2 xyoos, tseem yog menyuam yaus thiab neeg laus. Thaum muab tshuaj rau cov menyuam yaus me (nrog rau cov menyuam mos thaum yug los) hauv thawj lub limtiam ntawm lub neej, cov tshuaj yuav tsum tsis txhob siv ntau dua ob zaug hauv ib hnub, uas cuam tshuam nrog kev hloov lub plawv tsis ua haujlwm ntawm cov menyuam yaus. Vim tias qhov tseeb tias cov neeg laus laus yuav ua rau muaj kev mob plawv raum, Amoxiclav 2X yuav tsum siv nrog kev ceev faj hauv pawg neeg mob no, tab sis kev ua haujlwm hauv lub raum yuav tsum tau saib xyuas yog tias tsim nyog.

Tag nrho kev tshem tawm ntawm amoxicillin / clavulanic acid nyob rau hauv cov ntshav txo qis hauv cov xaim ncaj qha rau ib qho kev txo qis hauv kev ua haujlwm. Qhov txo qis ntawm amoxicillin tshem tawm yog qhov tshaj tawm piv rau clavulanic acid, txij li ntau dua ntawm amoxicillin yog tawm dhau los ntawm lub raum. Yog li, thaum muab tshuaj rau cov neeg mob uas lub raum tsis ua haujlwm, yuav tsum tau txhaj tshuaj kho kom tsis txhob muaj cov tshuaj amoxicillin ntau ntau thiab tswj cov qib clavulanic acid yuav tsum tau ua.

Thaum muab tshuaj rau cov neeg mob uas lub siab tsis ua hauj lwm zoo, yuav tsum ceev faj thaum xaiv ib koob thiab soj ntsuam daim siab ua haujlwm tas li.

Cov Tshuaj Hauv Tshuaj

Amoxicillin yog tshuaj tua kab mob ib nrab los ntawm pawg neeg penicillin (beta-lactam tshuaj tua kab mob) uas tiv thaiv ib lossis ntau tshaj li cov enzymes (feem ntau hu ua penicillin-khi cov protein) koom nrog biosynthesis ntawm peptidoglycan, uas yog cov txheej txheem tseem ceeb ntawm cov kab mob ntawm tes ua haujlwm. Kev txwv tsis pub peptidoglycan hluavtaws ua rau kev ua haujlwm tsis zoo ntawm lub xovtooj ntawm phab ntsa, feem ntau ua raws li cov cell lysis thiab cell tuag.

Amoxicillin raug pov tseg los ntawm beta-lactamases uas ua los ntawm cov kab mob tiv taus, thiab yog li ntawd, kev ua si spectrum ntawm amoxicillin ib leeg tsis suav nrog cov kab mob me me uas tsim cov enzymes no.

Clavulanic acid yog beta-lactam kev txuam nrog penicillins. Nws inhibits qee qhov beta-lactamases, yog li tiv thaiv qhov ua tsis tiav ntawm amoxicillin, thiab nthuav nws cov kev ua haujlwm spectrum. Clavulanic acid nws tus kheej tsis muaj qhov chaw mos ua rau muaj kev cuam tshuam loj heev rau kev kho mob.

Tshaj lub sijhawm dhau los ntawm qhov kev txwv qis tshaj plaws (T> IPC) yog suav tias yog qhov kev txiav txim siab tseem ceeb ntawm cov hauj lwm zoo ntawm amoxicillin.

Ob txoj haujlwm tseem ceeb ntawm kev ua rau amoxicillin thiab clavulanic acid yog:

inactivation los ntawm cov kab mob beta-lactamases uas tsis tau txhawm los ntawm clavulanic acid, suav nrog cov chav kawm B, C thiab D.

ib qho kev hloov pauv ntawm kev sib txuas ua ke ntawm penicillin, uas txo qis kev sib raug zoo ntawm cov tshuaj tua kab mob mus rau lub hom phiaj.

Lub zog tsis haum ntawm cov kab mob lossis cov txheej txheem ntawm lub efflux twj tso kua mis (thauj cov tshuab) tuaj yeem ua rau lossis tswj qhov tsis kam ntawm cov kab mob, tshwj xeeb tshaj yog cov kab mob gram-tsis zoo.

Cov txiaj ntsig tsis pub tsawg ntawm MIC rau amoxicillin / clavulanic acid yog cov tau txiav txim siab los ntawm European Pawg Neeg Saib Xyuas Kev Tshuaj Tiv Thaiv Kev Ua Si (EUCAST).

Amoxiclav ntsiav tshuaj ntau npaum rau cov neeg laus

Cov chav kawm thiab qhov ntau npaum li cas ntawm kev siv Amoxiclav yog txiav txim siab los ntawm tus kws kho mob koom nrog rau ntau yam - kev txhim kho, kev ua kom hnyav ntawm tus txheej txheem sib kis, nws thaj chaw. Nws tseem tseem xav ua lub chaw soj ntsuam kuaj saib qhov ua tau zoo ntawm kev kho mob siv cov kev tshawb fawb bacteriological.

Lub chav kawm ntawm kev kho mob yog 5-14 hnub. Lub sijhawm tiv thaiv ntawm kev kho mob yog txiav txim los ntawm tus kws khomob koom nrog. Txoj kev kho yuav tsum tsis pub ntev tshaj 14 hnub yam tsis muaj kev kuaj mob zaum ob.

Txij li cov ntsiav tshuaj ntawm kev sib xyaw ntawm amoxicillin thiab clavulanic acid ntawm 250 mg + 125 mg thiab 500 mg + 125 mg muaj qhov sib npaug ntawm clavulanic acid -125 mg, 2 ntsiav tshuaj ntawm 250 mg + 125 mg tsis sib npaug rau 1 ntsiav tshuaj ntawm 500 mg + 125 mg.

Sab sij huam

Kev noj cov Amoxiclav ntsiav tshuaj tuaj yeem ua rau ntau txoj kev tshwm sim:

• Mob plab ua pa - tsis qab los, xeev siab, ntuav raws caij nyoog, raws plab.
• Cov tshuaj muaj txiaj ntsig rau lub plab zom mov los ntawm kev noj Amoxiclav yog qhov tsaus ntuj ntawm tus hniav txha hniav laus, voos ntawm lub plab hnyuv (gastritis), mob ntawm tus me (enteritis) thiab cov hnyuv loj (colitis).
• Kev puas tsuaj rau hepatocytes (mob siab hauv hlwb) nrog rau kev nce qib ntawm lawv cov enzymes (AST, ALT) thiab bilirubin hauv cov ntshav, ua rau tsis muaj zog txog bile (cholestatic jaundice).
• Kev ua xua uas tshwm sim thawj zaug thiab tej zaum yuav muaj kev cuam tshuam los ntawm qhov txawv txav ntawm qhov txawv txav - los ntawm pob khaus ntawm daim tawv nqaij mus rau kev txhim kho qhov tsis nco.
• Kev tsis sib haum xeeb hauv cov ntshav hematopoietic - txo qis hauv qib ntawm leukocytes (leukocytopenia), platelets (thrombocytopenia), txo qis ntshav coagulability, hemolytic anemia vim muaj kev puas tsuaj ntawm ntau cov qe ntshav liab.
• Hloov pauv kev ua haujlwm ntawm lub hauv nruab nrab lub paj hlwb - kiv taub hau, mob taub hau, txhim kho nriaj.
• Kev mob ntawm cov nqaij ntshiv interstitial ntawm ob lub raum (interstitial nephritis), lub ntsej muag ua pob txhaws (crystalluria) lossis ntshav (hematuria) hauv cov zis.
• Dysbacteriosis yog kev ua txhaum ntawm microflora li qub ntawm cov roj ntsha ua rau muaj mob, vim yog kev rhuav tshem cov kab mob uas lawv nyob. Kuj, tawm tsam keeb kwm ntawm dysbiosis, ib sab phiv tuaj yeem yog kev txhim kho ntawm cov mob fungal.

Yog tias muaj kev phiv, kev noj tshuaj Amoxiclav nres.

Siv thaum cev xeeb tub thiab pub niam mis

Cov kev tshawb fawb tsiaj tsis tau qhia txog cov kev phom sij ntawm kev noj tshuaj thaum cev xeeb tub thiab nws cov nyhuv ntawm kev loj hlob hauv cov menyuam hauv plab.

Hauv ib txoj kev tshawb nrhiav rau cov poj niam nrog kev puas tsuaj ua ntej ntawm daim nyias nyias nyias lub cev, nws tau pom tias kev siv prophylactic nrog amoxicillin / clavulanic acid yuav cuam tshuam nrog kev pheej hmoo ntawm necrotizing enterocolitis hauv cov menyuam mos. Thaum cev xeeb tub thiab lactation, cov tshuaj tsuas yog siv yog tias muaj txiaj ntsig rau leej niam outweighs qhov kev pheej hmoo rau tus menyuam thiab menyuam. Amoxicillin thiab clavulanic acid hauv ib qho me me txeem mus rau hauv niam cov kua mis. Hauv cov menyuam mos tau txais kev pub niam mis, kev loj hlob ntawm kev xav rhiab, raws plab, zais plab ntawm lub plab ntawm lub qhov ncauj ua tau. Thaum noj Amoxiclav 875 + 125, nws yog qhov tsim nyog los daws qhov teeb meem ntawm kev txwv tsis pub mis niam.

Cov lus piav qhia tawm ntawm cov foos tso tawm

Cov tshuaj no muaj hauv cov qauv hauv cov ntsiav tshuaj uas muaj xim dawb los yog beige-dawb. Cov ntsiav tshuaj muaj oval biconvex duab.

Ib qho 625 mg ntsiav tshuaj muaj 500 mg ntawm amoxicillin trihydrate nrog 125 mg ntawm clavulanic acid (poov tshuaj ntsev).

Cov ntsiav tshuaj tuaj yeem tsim rau hauv cov kaus poom yas (15 ntsiav tshuaj txhua) lossis hauv cov kua xaim txhuas ntawm 5 lossis 7 daim.

1000 mg ntsiav tshuaj kuj raug coated, muaj ib daim duab oblong nrog beveled sawv. Ntawm lawv, ntawm ib sab tes, ib qho kev luam ntawm "AMS" yog thov, nyob rau lwm yam - "875/125". Lawv suav nrog 875 mg ntawm cov tshuaj tua kab mob thiab 125 mg ntawm clavulanic acid.

Sib xyaw nrog lwm yam tshuaj

• Nws yog qhov tsis tsim nyog siv ib txhij Amoxiclav thiab kev npaj ntawm anticoagulants tsis ncaj. Qhov no tuaj yeem ua rau nce sijhawm hauv prothrombin lub sijhawm.
• Kev sib cuam tshuam ntawm Amoxiclav thiab allopurinol ua rau muaj kev pheej hmoo ntawm exanthema.
• Amoxiclav txhim kho kev puas tsuaj ntawm metatrexate.
• Koj siv tsis tau ob qho tib si amoxicillin thiab rifampicin - cov no yog cov antagonists, kev siv ua ke siv lub zog tiv thaiv kev ua haujlwm ntawm ob qho tib si.
• Amoxiclav yuav tsum tsis txhob raug coj ua ke nrog tetracyclines lossis macrolides (cov no yog cov tshuaj tua kab mob bacteriostatic), nrog rau sulfonamides vim tias txo qis hauv cov nyhuv ntawm cov tshuaj no.
• Kev noj cov Amoxiclav txo cov kev ua kom muaj txiaj ntsig zoo hauv cov ntsiav tshuaj.

Cov kws kho mob tshuaj xyuas

Anna Leonidovna, kws kho mob, Vitebsk. Amoxiclav muaj txiaj ntsig ntau dua hauv kev kho mob ntawm ntau yam kab mob ua pa tsis xws li nws cov tshuaj tiv thaiv kab mob, amoxicillin. Kuv sau ntawv rau kev kawm txog 5 hnub, tom qab ntawd nws yog qhov tsim nyog yuav tsum tau coj cov tshuaj uas rov qab los kho microflora.

Veronika Pavlovna, urologist. Yawg Kryvyi Rih. Cov tshuaj no muaj cov nyhuv zoo heev rau cov kab mob hauv lub cev ntawm qhov chaw mos. Nws tsis tshua muaj kev phiv tshuaj, tib lub sijhawm kuv muab tshuaj tua kab mob, tom qab noj probiotics los kho microflora ib txwm.

Andrei Evgenievich, tus kws kho mob ENT, Polotsk. Kev siv cov tshuaj no los ntawm kev txhaj tshuaj tso cai rau koj kom sai sai qhov cuam tshuam ntawm kev mob hnyav thiab mob hnyav ntawm ENT kabmob. Cov tshuaj kho cov mob nyob hauv nruab nrab pob ntseg zoo. Ib qho ntxiv, cov neeg mob noj lub txiv qab zib tawm zoo.

Kev Ntsuam Xyuas Rau Neeg Mob

Victoria, Dnipropetrovsk. Siv raws li kws kho mob sau tseg los kho tus mob tonsillitis. Pom 5 hnub. Cov tshuaj tua kab mob pib rau hnub thib 3 mob. Tus kab mob subsided los ntawm ib feem peb. Kuv caj pas nres nres. Muaj mob raws plab, dhau li ntawm ob hnub, tom qab nws kuv pib noj cov tshuaj probiotics los kho cov microflora.

Alexandra, lub nroog Lugansk. Cov tshuaj no tau raug tshuaj los ntawm kws kho mob los kho tus mob pyelonephritis. Txoj kev kawm tau 7 hnub. Thawj 3 hnub hno - tom qab ntawd cov ntsiav tshuaj. Qhov hno no zoo dua. Txawm li cas los xij, kev txhim kho pib ncig hnub plaub. Tsis muaj kev mob tshwm sim. Puas yog qhov ncauj qhuav.

Tamara, lub nroog ntawm Boyarka. Lawv txhaj kuv cov tshuaj no rau kev kho mob kis mob rau poj niam. Nws mob heev, cov nqaij doog tseem nyob ntawm thaj chaw txhaj tshuaj. Txawm li cas los xij, tom qab ib lub lim tiam tsis muaj ib txoj kab tseem tshuav hauv lub luag nyav ntawm cov kab mob tseem ceeb.

Cov lus qhia rau siv Amoxiclav Quicktab

Ua ntej noj, cov ntsiav tshuaj yuav tsum tau yaj hauv 100 ml dej (qhov dej yuav ntau dua). Do cov txheej kom zoo ua ntej siv. Koj tseem tuaj yeem zom cov ntsiav tshuaj, nws yog qhov zoo dua los siv cov tshuaj ua ntej noj. Cov neeg laus thiab menyuam yaus tom qab muaj hnub nyoog 12 xyoos yuav tsum noj 1 ntsiav tshuaj ib hnub. 625 mg 2-3 zaug ib hnub. Hauv cov mob hnyav, 1 lub tshuaj kho mob raug xaj tau. 1000 mg 2 zaug ib hnub. Txoj kev kho yuav tsum tsis pub ntev tshaj 2 lub lis piam.

Qee zaum tus kws kho mob tuaj yeem sau tshuaj analogues ntawm cov tshuaj, piv txwv li, Flemoklav Solutab thiab lwm tus.

Amoxiclav nrog angina

Tshuaj Amoxiclav mob caj pas ib tus neeg laus tshuaj 1 ntsiav tshuaj. 325 mg ib zaug txhua 8 teev. Lwm txoj kev kho mob ntxiv yuav tsum noj 1 lub tshuaj ib zaug txhua 12 teev. Tus kws kho mob yuav sau ntawv muab tshuaj rau cov tshuaj kom ntau dua yog tias tus kab mob ntawm cov neeg laus hnyav. Kev kho mob ntawm angina hauv menyuam yaus cuam tshuam nrog kev siv ncua ntawv. Raws li txoj cai, 1 diav yog tshuaj noj (ib lub tshuaj tsuas yog 5 ml). Qhov ntau zaus ntawm kev pub nkag yog txiav txim los ntawm tus kws kho mob, cov lus pom zoo uas yog qhov tseem ceeb ua raws. Kev noj cov tshuaj Amoxiclav rau cov menyuam yaus nrog angina nyob ntawm qhov mob hnyav heev.

Amoxiclav muab rau cov mob caj pas

Puas Amoxiclav pab nrog mob hlab ntsws, nyob ntawm qhov ua thiab cov yam ntxwv ntawm chav kawm ntawm tus kab mob. Qhov ntau npaum li tau txiav txim siab los ntawm tus kws kho mob otolaryngologist. Nws raug pom zoo kom koj noj 500 mg tshuaj peb zaug ib hnub. Pes tsawg hnub rau kev noj tshuaj yog nyob ntawm qhov mob hnyav ntawm tus kab mob. Tab sis tom qab cov tsos mob ploj, koj yuav tsum tau noj cov tshuaj rau ob hnub ntxiv.

Kev sib txuam

Nrog tib lub sijhawm tswj hwm ntawm cov tshuaj nrog qee cov tshuaj, qhov tsis xav tau tshwm sim, uas yog vim li cas cov ntsiav tshuaj, phoov thiab cov tshuaj ua haujlwm ntawm cov tshuaj yuav tsum tsis txhob siv nrog rau cov tshuaj ntau dhau los.

Ib txhij siv cov tshuaj nrog Glucosamine, tshuaj tiv thaiv kab mob, aminoglycosides, tshuaj laxative kom tsawg dua qhov kev nqus ntawm Amoxiclav, thaum noj ib txhij nrog Ascorbic acid - kev nqus yog nrawm.

Nrog rau kev kho mob ib txhij nrog phenylbutazone, diuretics, NSAIDs, Allopurinol thiab lwm yam tshuaj uas thaiv cov leeg, ua rau muaj qhov nce ntawm cov tshuaj amoxicillin tshwm sim.

Yog tias kev tswj hwm ib txhij ntawm cov tshuaj tiv thaiv anticoagulants thiab Amoxiclav ua tau, lub sijhawm prothrombin nce ntxiv. Yog li ntawd, nws yog ib qho tsim nyog yuav tsum tau sau nyiaj hauv cov lus sib txuam zoo li no.

Amoxiclav tsub kom lub cev tsis lom ntxiv Methotrexate thaum noj nws.

Thaum noj Amoxiclav thiab Allopurinol qhov ntxim nyiam ntawm exanthema nce.

Yuav tsum tsis txhob coj tib lub sijhawm Disulfiramthiab Amoxiclav.

Tus kws tswj hwm kev sib ntaus yog amoxicillin thiab RifampicinCov. Cov tshuaj ua rau lub cev ua rau lub zog ua haujlwm tsis zoo.

Cov tshuaj tiv thaiv Amoxiclav thiab bacteriostatic (tetracyclines, macrolides), thiab sulfanilamides yuav tsum tsis txhob noj tib lub sijhawm, vim tias cov tshuaj no tuaj yeem txo Amoxiclav cov hauj lwm zoo.

Probenecid tsub kom lub siab ntawm amoxicillin thiab ua rau qeeb nws cov kev tshem tawm.

Thaum siv Amoxiclav, qhov kev ua tau zoo ntawm kev cuam tshuam ntawm kev tiv thaiv qhov ncauj yuav txo qis.

Cov Ntaub Ntawv Ntxiv

Yog tias cov tshuaj siv tau ntev, nws yog ib qho tsim nyog los saib xyuas lub siab ua haujlwm ntawm lub siab, cov ntshav cov ntshav thiab cov raum ntawm tus neeg mob. Yog hais tias tus neeg mob tau kho lub raum lub siab, nws yog qhov tsim nyog yuav tau kho lub koob tshuaj lossis nce ntxiv lub sijhawm ntawm cov koob tshuaj ntawm cov tshuaj. Nws yog qhov zoo dua rau kev noj tshuaj nrog zaub mov. Thaum kis superinfection (qhov pom ntawm microflora tsis zoo rau cov tshuaj tua kab mob no), nws yog ib qho tsim nyog yuav tau hloov cov tshuaj. Vim tias qhov ua rau hla kev tsis haum nrog cephalosporins nyob rau hauv cov neeg mob rhiab rau penicillins, nws tsis tsim nyog siv cov tshuaj tua kab mob no ua ke.

Thaum noj tshuaj, koj yuav tsum haus kua ntau hauv cov kua thiaj li zam dhau qhov tsim ntawm amoxicillin muaju hauv cov zis.

Koj yuav tsum paub tias muaj cov koob tshuaj loj heev hauv cov tshuaj tua kab mob hauv lub cev tuaj yeem ua rau muaj qhov tsis zoo rau cov ntshav qabzib (yog Benedict reagent lossis Fleming's cov tshuaj siv los txiav txim rau nws). Cov txiaj ntsig zoo dua qub nyob rau hauv qhov no yuav muab kev siv cov tshuaj tiv thaiv enzymatic nrog glucosidase.

Txij li thaum cov kev mob tshwm sim los ntawm cov leeg muaj zog thaum siv yeeb tshuaj, nws yog qhov yuav tsum ua tib zoo tsav tsheb (tsheb) lossis koom nrog kev ua si uas yuav tsum muaj kev xav ntau ntxiv, tawm tsam ceev thiab mob siab.

Nws yog tso rau ntawm lub hwj tshuaj.

Tso Tawm Cov Ntawv

Tam sim no, cov chaw tsim tshuaj ntawm cov tshuaj no tsim nws hauv cov ntawv hauv qab no:

• hauv cov yeeb yaj kiab-coated ntsiav tshuaj
• nyob rau hauv daim ntawv ntawm hmoov, lub hom phiaj tseem ceeb ntawm cov uas yog cov khoom lag luam tawm ntawm kev ncua,
• nyob rau hauv daim ntawv ntawm lyophilized hmoov, uas yog npaj rau cov tshuaj txhaj tshuaj.

Nco ntsoov tias ua ntej siv cov tshuaj no hauv daim ntawv ntawm hmoov, nws yuav tsum tau diluted hauv cov kua tshwj xeeb - ib qho kev daws teeb meem. Lossis koj tuaj yeem siv cov dej ntshiab. Txhua yam ntau npaum ntawm cov ntaub ntawv muab tshuaj ntawm tus neeg sawv cev no peb yuav xav txuas ntxiv.

Amoxiclav nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj muaj qhov sib txawv ntawm cov tshuaj yeeb dej caw. Lawv muaj nyob rau hauv cov khw muag tshuaj saw hauv peb version:

Tsis tas li ntawd, nyob rau hauv cov ntsiav tshuaj ntawm Amoxiclav muaj ib qho ntxiv uas muab kev tsim ntawm viscosity ntawm cov tshuaj. Cov no suav nrog magnesium stearate, silicon dioxide, ntxiv rau cellulose thiab citric acid. Cov tshuaj Amoxiclav nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj ua ntej siv yog pom zoo kom yaj hauv dej hauv ib qho ntawm 100 ml. Yog tias nws tsis tuaj yeem ua qhov no, koj yuav tsum ua tib zoo noj lub ntsiav tshuaj, thiab tom qab ntawd haus cov tshuaj nrog dej txaus.

Amoxiclav nyob rau hauv daim ntawv ntawm hmoov uas npaj rau kev npaj ntawm qhov kev ncua yog coj ntawm qhov ncauj. Nws muaj nyob hauv peb daim ntawv:

• Amoxiclav 125Cov. Ntxiv rau cov tshuaj tseem ceeb amoxicillin, uas muaj 125 mg nyob rau hauv qhov kev npaj no, nws muaj ntsev ntawm clavulanic acid nyob rau hauv ib qho nyiaj ntawm 31.25 mg, nthuav tawm hauv daim ntawv ntawm trihydrate,
• Amoxiclav 250Cov. Cov tshuaj sib xyaw ua kom hmoov muaj 250 mg ntawm cov tshuaj tua kab mob thiab ntxiv rau lub suab ntsev rau hauv ib qhov nyiaj ntawm 62,5 mg,
• Amoxiclav 400Cov. Nws muaj 400 mg ntawm amoxicillin thiab clavulanic acid hauv qhov npaum li cas ntawm 57 mg.

Raws li cov tshuaj ntxiv, cov pos hniav, sodium saccharinate, silicon dioxide, thiab citric acid yog nyob rau hauv qhov kev ncua.

Thaum npaj qhov kev ncua, cov lus qhia rau kev siv raug ua raws. Lub hmoov ua kom yaj thaum lub sijhawm dej. Lub raj mis txhawm rau ua kom tiav kev cuam tshuam ntawm lub Cheebtsam yog shaken ruaj khov.

Cov hmoov ua rau cov tshuaj tua kab mob hauv lub cev. Cov chaw tsim tshuaj paus tsim ob hom:

• Amoxiclav 500Cov. Cov ntsiab lus ntawm cov tshuaj tseem ceeb hauv nws yog 500 mg. Nws yog nthuav tawm nyob rau hauv daim ntawv ntawm sodium ntsev. Tsis tas li ntawd, cov ntsev ntawm clavulanic acid nyob rau hauv daim ntawv ntawm cov poov tshuaj ntsev ntawm 100 mg yog tam sim no.
• Amoxiclav 1000Cov. Nws muaj amoxicillin nyob rau hauv ib qho nyiaj ntawm 1000 mg thiab 200 mg ntawm acid.

Rau kev txhaj tshuaj rau hauv lub cev, qhov kev ncua yog muab los ntawm diluting cov hmoov qhuav thiab ib qho kua dej ua rau Txoj kev lis ntshav. Cov tshuaj tiav tas yog txhaj dav hlau lossis nrog dauv dej. Thaum cov tshuaj raug tswj hwm los ntawm cov dav hlau txoj kev, lawv sim tsav nws mus rau hauv cov leeg sai li sai tau. Qhov no ua kom qhov ua tiav sai ntawm qhov xav tau kho kho kom haum, thiab tseem pab txhim kho tus neeg mob tus mob. Yog tias xav tau qhov ua haujlwm ntawm cov tshuaj rau lub sijhawm ntev, tom qab ntawd cov dej qaug tshuaj ntawm cov tshuaj yog nqa tawm ntawm cov leeg.

Cov tshuaj no muaj qee cov qauv tshuaj uas hloov cov tshuaj tseem ceeb yog tias nws tsis muaj nyob hauv cov tsev muag tshuaj:

Hauv cov khw muag tshuaj, tus nqi ntawm Amoxiclav hmoov yog nyob rau nruab nrab 120 rCov. Tus nqi ntawm cov ntsiav tshuaj lom zem ntau nyob ntawm qhov kev mloog ntawm cov tshuaj nquag, nrog rau daim ntawv tso tawm. Qhov nruab nrab, tus nqi teev rau hom tshuaj no txawv ntawm 230 txog 450 p. rau ib pob.

Cov lus qhia rau siv Amoxiclav hauv daim foos

Txog kev kho mob rau cov neeg mob me me uas muaj 12 xyoos nrog lub cev hnyav dua 40 kg, thiab cov laus, Amoxiclav 250 mg feem ntau yog kho mob. Tus neeg mob yuav tsum noj ib ntsiav tshuaj ib hnub txhua 8 teev. Thaum lub sij hawm kho nrog Amoxiclav 500 mg, kev noj ntau npaum li 3 zaug hauv ib hnub, ib ntsiav tshuaj. Rau cov neeg laus uas muaj kev mob hnyav nrog kev mob hnyav, Amoxiclav 1000 mg yog tau txais kev kho mob. Tus neeg mob yuav tsum noj ib ntsiav tshuaj ib hnub ob zaug. Lub sijhawm kho nrog cov tshuaj no hauv cov ntawv sau sib txawv txav ntawm 5 mus rau 14 hnub. Yog tias cov tshuaj tua kab mob siv tau ntev, tom qab ntawd qhov tshwm sim tsis zoo yuav tshwm sim.

Ua ntej siv cov ntsiav tshuaj Amoxiclav, nws yog ib qho tsim nyog yuav tsum yaj nws hauv ib nrab dej khob dej. Qhov sib xyaw ua ke yuav tsum ua kom nquag. Tsuas yog tom qab no, qhov muaj pes tsawg leeg yuav tsum quag cawv. Yog tias tsis muaj dej nyob ze, tom qab ntawd cov ntsiav tshuaj yuav tsum sib zog ua ntej yuav nqos, thiab tom qab ntawd ntxuav tawm nrog cov dej kom ntau.

Cov lus qhia rau siv Amoxiclav hauv daim ntawv ncua

Rau kev kho mob ntawm cov kab mob uas tshwm sim hauv cov menyuam yaus, Amoxiclav nyob rau hauv daim ntawv ntawm kev ncua yog feem ntau siv. Thaum kho cov menyuam mos thiab menyuam mos txij thaum muaj hnub nyoog peb xyoos, txoj kev noj yuav tsum ua tib zoo xaiv lub sijhawm cov tshuaj. Txhawm rau ua kom yooj yim qhov tshuaj ntawm cov tshuaj thaum kho, tshuaj ntsuas qhov ntsuas nyob hauv pob nrog cov tshuaj.

Rau cov menyuam loj dua, qhov tshuaj yog ib dausCov. Hauv cov lus qhia uas txuas nrog rau cov tshuaj, koj tuaj yeem nrhiav tau cov ntsiav tshuaj tshwj xeeb uas koj tuaj yeem ua kom raug tseeb qhov ntau npaum ntawm cov tshuaj rau tus menyuam, nyob ntawm qhov hnyav thiab hnub nyoog.

Rau txoj kev kho kom zoo, cov tshuaj yuav tsum noj 2 zaug hauv ib hnub txhua 12 teev. Los yog qhov daws tau tuaj yeem siv tom qab 8 teev peb zaug thaum nruab hnub. Tus kws kho mob tuaj yeem txiav txim siab noj ntau npaum li cas, nrog rau xaiv cov kev tswj hwm kev kho mob kom tsim nyog. Koj yuav tsum tsis txhob sau cov tshuaj no rau koj tus kheej, txij li kev noj cov tshuaj nyob rau hauv qhov tsis zoo yuav ua rau tus mob noj ntau dhauCov. Thiab qhov no yuav muaj kev tsis zoo rau kev noj qab haus huv.

Kev kho mob Amoxiclav thaum cev xeeb tub

Nws yog qhov tsis tsim nyog sau tshuaj rau Amoxiclav thaum cev xeeb tub los kho kab mob ntawm ib qho kev sib kis. Qhov no yog tias cov tshuaj uas muaj nyob rau hauv qhov muaj pes tsawg leeg ntawm cov tshuaj no tuaj yeem nkag rau hauv lub tsho me nyuam hauv plab tsis muaj teeb meem, thiab tsis tas li ntawd, cov tawm hauv niam cov kua mis.

Cov yeeb yam ntawm lub ntsej muag no tuaj yeem ua rau kev xav tias kev siv tshuaj ua cev xeeb tub yuav cuam tshuam tsis zoo rau kev noj qab haus huv ntawm tus menyuam.

Rau kev kho mob ntawm poj niam cev xeeb tub, cov tshuaj no yog siv raws li kev qhia. Thaum kho, lawv ua raws li cov lus qhia. Nws yog tshuaj rau cov poj niam hauv "txoj haujlwm txaus siab" tsuas yog qhov ua tau ntawm cov tshuaj yog siab dua qhov kev pheej hmoo uas yuav tshwm sim rau cov menyuam hauv plab. Vim li cas tias qhov tseem ceeb sib xyaw ntawm cov tshuaj no yooj yim nkag mus rau niam mis, thaum lactation, yog tias xav tau kev kho mob, kev pub mis niam kom nres thiab pub mis ntawm cov khoom sib tov sib xyaw.

Sab sij huam

Thaum kws kho mob xaiv ib cov tshuaj xws li Amoxiclav los kho kab mob, tus neeg mob yuav muaj cov kev mob tshwm sim hauv qab no:

• Tsis qab los noj mov, xeev siab. Ntxiv rau, cov tsos mob txais tau ntawm cov kab mob xws li colitis, gastritis, thiab ua kom tawv nqaij txha hniav laus. Kev ua haujlwm ntawm daim siab ua haujlwm tau txiav txim siab hauv cov mob hnyav. Hloov pauv kev suav hauv ntshav kuj tseem yuav tshwm sim, cov tsos mob ua cim ntawm lub siab ua haujlwm, kab mob siab tuaj yeem tshwm sim. Nws tsim nyog pom tias cov kev mob tshwm sim feem ntau tshwm sim hauv cov neeg mob hauv cov laus,
• Mob taub hau, kiv taub hau thiab pw tsaug zog. Hyperactivity los yog kev coj cwj pwm tsis tsim nyog ntawm tus neeg mob noj Amoxiclav tseem yuav tshwm sim. Kev qaug dab peg tuaj yeem tshwm sim hauv cov neeg mob uas mob raum yog tias Amoxiclav noj ntau dua,
• mob ntsws thrombocytopenia, mob thrombocytosis,
• khaus, qhov tshwm sim ntawm lom epidermal necrolysis.

Thaum Amoxiclav noj ntev ntev, nws muaj peev xwm kev pheej hmoo ntawm kev kub taub hau.

Nws tsim nyog sau cia tias cov kev cuam tshuam uas tau teev los saum toj no feem ntau tshwm sim thaum kho nrog cov tshuaj no lossis tam sim ntawd tom qab kev kho tiav. Txhua qhov kev tsis haum xav tau qhov thim rov qab, txawm li cas los xij, muaj mob lub siab yuav tshwm sim hnyav heev. Lawv tshwm sim feem ntau hauv cov neeg mob uas muaj daim siab pathologies, lossis tuaj yeem tshwm sim thaum siv cov tshuaj hepatoxic.

Xaus

Amoxiclav yog yeeb tshuaj uas koom nrog pawg pawg ntawm penicillin tshuaj. Nws tuaj yeem siv rau hauv kev kho mob ntawm ntau hom kabmob. Cov tshuaj muaj cov tshuaj tua tau zoo, uas tso cai rau koj kom sai sai rau tus neeg mob ntawm tus mob uas tau tshwm sim. Qhov cuab yeej no muaj nyob hauv cov khw muag tshuaj ua ntau hom.

Nws yog tso tawm hauv daim ntawv ntawm cov ntsiav tshuaj, hmoov. Kev kho kab mob tuaj yeem nqa tawm ntawm menyuam yaus thiab cov laus. Lawm, qhov ntau npaum ntawm cov tshuaj rau cov pawg ntawm cov neeg mob nws txawv. Thaum cev xeeb tub, cov tshuaj no tsis pom zoo. Qhov kev sib txuam no yog txuam nrog, ua ntej txhua yam, nrog qhov tseeb tias cov tshuaj uas muaj nyob hauv cov tshuaj no yooj yim nkag rau hauv lub tsho me nyuam thiab cov kua mis. Yog li, nws raug nquahu kom kho cov kab mob sib kis thaum cev xeeb tub nrog kev pab ntawm lwm txoj kev.

Thaum lub sijhawm pub mis, nws yog ib qho tsim nyog yuav tsum tau tso tseg kev pub mis niam thiab hloov chaw rau nws nrog zaub mov nrog sib tov. Nws tsis pom zoo rau nws tus kheej nqa tawm kev kho mob nrog Amoxiclav (ntsiav tshuaj), vim tias xaiv cov tshuaj tsis yog yuav ua rau muaj mob. Nyob rau hauv cov xwm txheej zoo li no, nws yog ib qhov tsim nyog los yaug lub plab thiab coj lub tshuab hluav taws xob.

Amoxiclav analogs

Muaj ib tug xov tooj ntawm cov analogues ntawm cov tshuaj no. Tus nqi ntawm analogues nyob ntawm, ua ntej ntawm tag nrho cov, ntawm cov chaw tsim tshuaj paus ntawm cov tshuaj. Muaj cov analogues ntawm kev muag khoom pheej yig dua Amoxiclav. Rau cov neeg mob xav paub txog dab tsi tuaj yeem hloov cov tshuaj tua kab mob no, cov kws kho mob tshwj xeeb muaj cov npe loj ntawm cov tshuaj. Qhov no txhais tau Moxiclav, Co-Amoxiclav, Augmentin, Clavocin, Flemoklav, Medoclave, Baktoklav, Ranklav, AmovicombTxawm li cas los xij, tsuas yog ib tus kws kho mob thiaj li yuav tsum sau daim ntawv hloov chaw tuaj hloov xwb. Koj tuaj yeem xaiv qhov pheej yig dua nyob hauv cov ntsiav tshuaj, piv txwv li Augmentin. Koj tseem tuaj yeem xaiv ib tus Lavxias analogue, piv txwv li, Amoxicillin.

Qhov twg yog qhov zoo dua: Amoxiclav lossis Augmentin?

Dab tsi yog cov muaj pes tsawg leeg ntawm Amoxiclav thiab Augmentin, cov tshuaj no txawv li cas? Ob qho ntawm cov cuab yeej no muaj cov khoom sib thooj sib xws, uas yog, qhov tseeb, qhov no yog qhov qub. Raws li, cov nyhuv pharmacological ntawm cov tshuaj yuav luag zoo ib yam, nrog rau kev phiv. Tsuas yog cov neeg tsim khoom ntawm cov tshuaj no txawv.

Amoxiclav thaum cev xeeb tub thiab lactation

Amoxiclav cev xeeb tub tuaj yeem siv tau yog tias cov nyhuv xav tau tshaj qhov tsim kev puas tsuaj rau tus menyuam hauv plab. Kev siv tshuaj Amoxiclav nyob rau thaum ntxov ntawm kev xeeb tub yog qhov tsis xav tau. 2 lub hlis thiab 3 peb hlis muaj ntau dua, tab sis txawm tias lub sijhawm no kev noj tshuaj ntawm Amoxiclav thaum cev xeeb tub yuav tsum pom tseeb meej heev. Amoxiclav pub niam mis tsis txhob sau ntawv tshuaj, txij li cov tshuaj ua kom nquag plias nkag mus rau niam mis.

Amoxiclav tshuaj xyuas

Hauv kev sib tham txog cov tshuaj Amoxiclav, kev tshuaj xyuas ntawm cov kws kho mob thiab cov neeg mob feem ntau yog qhov zoo. Nws raug sau tseg tias cov tshuaj tua kab mob ua tau zoo rau kev kho mob ntawm txoj hlab ua pa, thiab nws haum rau ob leeg rau cov laus thiab menyuam yaus. Cov kev tshuaj xyuas tau hais txog qhov ua tau zoo ntawm cov tshuaj rau cov hlab ntsws, rau kev tshaj tawm otitis, rau kev kis mob ntawm qhov chaw mos. Raws li txoj cai, cov neeg mob laus noj cov ntsiav tshuaj ntawm 875 mg + 125 mg, nrog rau txoj kev noj tshuaj kom haum, txoj kev daws mob sai sai. Hauv kev txheeb xyuas, nws tau sau tseg tias tom qab ib lub sijhawm ntawm kev siv tshuaj tua kab mob, nws yog ntshaw kom siv tshuaj uas ua kom rov zoo li qub microflora.

Kev tshuaj xyuas ntawm Amoxiclav raug muab ncua cia kuj yog qhov zoo. Cov niam txiv sau tias nws yooj yim los muab cov khoom rau cov menyuam yaus, vim nws muaj qab ntxiag thiab zoo li pom tau los ntawm menyuam yaus.

Tus nqi Amoxiclav, yuav qhov twg

Nqi Amoxiclav ntsiav tshuaj 250 mg + 125 mg qhov hnyav 230 rubles rau 15 pcs. Yuav cov tshuaj tiv thaiv 500 mg + 125 mg tuaj yeem them nqi ntawm 360 - 400 rubles rau 15 pcs. Npaum li cas yog cov ntsiav tshuaj 875 mg + 125 mgnyob ntawm qhov chaw muag khoom. Qhov nruab nrab, lawv cov nqi yog 420 - 470 rubles rau 14 pcs.

Nqi Amoxiclav Quicktab 625 mg - los ntawm 420 rubles rau 14 pcs.

Raug tshem tawm tus nqi Amoxiclav rau menyuam yaus - 290 rubles (100 ml).

Nqi Amoxiclav 1000 mg nyob rau hauv Ukraine (Kiev, Kharkov, thiab lwm yam) - los ntawm 200 hryvnias rau 14 daim.