Acecardol: cov lus qhia rau kev siv, cim, xyuas thiab analogues

Cov tshuaj "Acecardol" yog cov kua qaub uas yog acetylsalicylic acid, uas yaj tau ncaj qha rau hauv txoj hnyuv. Nws yog cov tshuaj tsis-steroidal nrog cov nyhuv tshuaj tiv thaiv. Acetylsalicylic acid muaj nyob rau hauv cov koob tshuaj sib txawv hauv txhua qhov Acecardol analogues.

Nws muaj peev xwm los thaiv qhov kev sib txuas ntawm thromboxane thiab inhibit tus txheej txheem ntawm kev sib xyaw platelets rau hauv cov ntshav. Cov nyhuv ntawm Acecardol raug pom txawm tias muaj kev siv tshuaj me me ntawm nws txoj kev siv thiab mob siab nrog kev siv ib zaug rau ib lub lim tiam. Hauv kev txhaj tshuaj siab, cov tshuaj muaj cov tshuaj tua kabmob (antipyretic, analgesic) thiab tshuaj tiv thaiv.

1 ntsiav tshuaj muaj 50, 100 lossis 300 mg ntawm cov tshuaj nquag acetylsalicylic acid. Cov tshuaj yog zwm rau cov chaw kho mob thiab chaw muag tshuaj ntawm NSAIDs, tus sawv cev antiplatelet.

Lub hauv paus ntawm cov txheej txheem ntawm kev ua haujlwm yog qhov ua rau muaj kev cuam tshuam ntawm cyclooxygenase los ntawm cov kev ua haujlwm nquag, uas ua rau inhibition ntawm thromboxane A2 ntau lawm thiab txo qis hauv platelet aggregation. Cov txiaj ntsig antiplatelet tiav los ntawm kev noj ib ntsiav tshuaj kav rau ib lub lim tiam.

Cov lus qhia rau kev siv Acecardol

Acecardol txwv tsis pub thrombosis, tiv thaiv kev txhim kho thiab txhim kho kev mob plawv, ischemic strokes, thiab thromboembolism. Kev siv acecardol ntev ntev nce lub sijhawm thiab lub neej zoo ntawm cov neeg mob. Cov neeg mob uas tau ntxhov siab los ntawm lub plawv dhia ceev ceev tau ceeb toom txog kev txhim kho hauv lawv tus mob, kev noj qab nyob zoo thiab muaj ntshav siab.

Acecardol yog tshuaj rau lub qog tsis khov tsis haum lub hlwb, kom tiv thaiv cov kab mob myocardial infarction, tiv thaiv kom tsis txhob mob ntsws (nrog rau nws cov ceg) thiab cov hlab ntsha sib sib zog nqus (nrog immobility ntev, piv txwv li, thaum lub sijhawm phais mob ntev).

Cov lus qhia rau siv Acecardol dosage

Tham nrog koj tus kws kho mob hais txog koob tshuaj zoo tshaj plaws niaj hnub rau koj. Acetylsalicylic acid npaj ntawm 50-150 mg ib hnub twg yog npaj rau kev siv mus ntev. Raws li txoj cai, lawv tau tsim rau lub neej yog tias tsis muaj kev phiv loj heev.

Muaj qhov nruab nrab tshuaj ntawm cov tshuaj uas siv hauv kev tiv thaiv ntau yam kab mob. Txhawm rau tiv thaiv kom tsis txhob mob myocardial infarction, tsis muaj thiab nyob rau ntawm qhov muaj kev pheej hmoo, thromboembolism ntawm lub ntsws ntawm cov leeg ntshav thiab nws cov ceg, sib zog nqus cov hlab ntsha muaj cai yog 100 mg rau ib hnub ib hnub lossis 300 mg txhua hnub thib ob (nws yog ib qho zoo kom chew thawj ntsiav tshuaj rau kev nqus sai).

Daim ntawv thov nta

Thaum noj cov tshuaj Acekardol, kev ceev faj yuav tsum tau siv thaum tsav tsheb, cov txheej txheem thiab thaum ua lwm yam kev muaj peev xwm txaus ntshai uas xav tau kev nce siab ntawm kev saib xyuas thiab ceev ntawm psychomotor kev tsis haum.

Thaum lub sijhawm kho mob nrog kev npaj raws li cov tshuaj acetylsalicylic acid, yuav tsum kuaj ntshav tsis tu ncua, vim tias cov tshuaj no pab txhawb nws qhov tseem ceeb. Nrog rau lub sijhawm ntev thiab kev siv tsis tau ntawm acecardol, qhov kev pheej hmoo ntawm kev tsim muaj cov ntshav los sab hauv yog qhov zoo.

Thaum noj ib txhij nrog haus dej cawv, lub cev muaj txiaj ntsig ntawm cawv ntau ntxiv, qhov kev pheej hmoo ntawm los ntshav ntau ntxiv thiab lawv lub sijhawm lengthens, thiab qhov kev pheej hmoo ntawm kev puas tsuaj rau cov qog ua kua ntawm lub plab zom mov nce ntxiv.

Acecardol potentiates qhov tshwm sim ntawm cov tshuaj xws li:

- methotrexate,
- heparin,
- Cov tshuaj insulin
- mob glycosides.

Acekardol - cov ntsiav tshuaj zoo li cas los ntawm

Cov kws kho mob tau sau ntawv rau Acekardol ntsiav tshuaj rau kev tiv thaiv, tom qab phais mob ntawm lub plawv thiab cov hlab ntsha lossis kom tsis txhob muaj kev pheej hmoo ntawm txoj hlab ntshav thib ob hauv cov neeg mob uas nyuam qhuav muaj. Qhov zoo nkaus li tsis xis nyob thiab mob hauv siab hauv siab (angina pectoris) kuj ua lub luag haujlwm pib noj Acecardol ua qhov tseem ceeb ntawm kev kho txoj kev kho mob.

Raws li cov lus qhia rau kev siv, Acekardol belongs rau pawg ntawm cov tshuaj antiplatelet. Nws qhov kev ua yog hais txog tiv thaiv kom tsis txhob lo cov kab mob thiab cov ntshav liab. Qhov tshwm sim ntawm cov tshuaj Acekardol ntawm cov txheej txheem hematopoiesis yog los pab txhawb kev ywj pheej ntawm capillaries, lub dilution ntawm cov ntshav txhaws, uas tau tsim vim pathological tshwm sim uas tshwm sim hauv lub plawv thiab cov hlab ntsha.

Cov tshuaj nquag uas ua rau lub hauv paus ntawm cov muaj pes tsawg leeg ntawm cov tshuaj Acecardol yog acetylsalicylic acid, paub txog nws cov kev kho kom dav. Cov tshuaj hauv qab no yog siv los ua ntu nyob hauv feem pua:

tsis tshua muaj molecular phaus polyvinylpyrrolidone - 1.8%,
pob kws nplej siab - 9.5%,
microcrystalline hmoov ntawm tsob nroj polysaccharide (cellulose) - 5.6%,
stearic acid (lossis magnesium stearate) - 0.6%,
talc - 1.7%
cov piam thaj mis mos monohydrate (lactose) - 53%.

Daim ntawv tso tawm

Lub xeev ntawm cov tshuaj Acecardol, nyob rau hauv uas nws cov tshuaj kho tau qhov tseeb tag nrho, yog cov ntsiav tshuaj coated nrog cov kua qaub-tiv thaiv dawb plhaub nrog cov tshuaj ntsiab lus ntawm 50, 100 lossis 300 mg. Qhov muaj pes tsawg leeg uas nws tau ua rau muab cov tawv nqaij zom zoo rau lub cachet (tshuaj yaj yeeb tshuaj):

cellulose acetate - tiv thaiv kev txhim kho nyob rau hauv txoj hlab pas,
titanium dioxide - neutralizes cov nyhuv ntawm hydrochloric acid,
cov roj taum castor (ricinoleic acid) - txhim kho thiab ua kom muaj kev tso cai ntawm cov ntsiav tshuaj dhau los ntawm txoj hlab nqos mov.

Pharmacodynamics thiab pharmacokinetics

Cov txheej txheem ntawm kev ua ntawm tus neeg ua haujlwm antiplatelet Acekardol, raws li cov lus qhia rau kev siv, yog ua raws kev thaiv ntawm kev nkag mus ntawm thromboxanes mus rau qhov txheej-txheej uas khi ntawm cyclooxygenase. Cov txheej txheem inhibition pab nres lub synthesis ntawm prostanoids thiab txwv ntshav platelet, vim tias cov nyhuv ntawm antipyretic, txo qhov mob thiab tshem tawm cov tsos mob ua tiav.

Cov tshuaj Acekardol, nkag mus rau hauv txoj hnyuv tom qab kev tswj hwm ntawm qhov ncauj, plam nws cov kua qaub-tiv thaiv txheej, thiab cov tso tawm acetylsalicylic acid yuav pib nqus nyob rau sab qaum kev ntawm txoj hnyuv me. Peb teev tom qab noj Acecardol, qhov siab tshaj plaws ntawm cov khoom hauv cov ntshav ntshav tau mus txog. Kev nqhis ntawm cov tshuaj tshwm sim los ntawm tubular lub raum zais zis (60% nyob rau hauv daim ntawv tsis hloov pauv, 40% hauv hom tshuaj metabolites).

Acecardol - cim qhia siv

Antiplatelet tshuaj tau raug muab rau kev tiv thaiv ntawm cov ntshav txhaws thiab rau kev kho mob ntawm cov ntshav ncig. Acecardol, raws li cov lus qhia, yog qhia rau siv los tiv thaiv kev txhim kho ntawm cov kab hauv qab no:

postoperative thromboembolism (tom qab shunting, arterial angioplasty),
exacerbations ntawm mob plawv (cov tsos mob lub ntsiab yog tsis khov kho angina)
mob stroke
myocardial infarction (yog tias muaj kev pheej hmoo tsim teeb meem xws li ntshav qab zib mellitus, rog rog, laus hnub nyoog, thiab lwm yam),
ntshav txhaws nyob rau hauv cov leeg ntshav tob.

Cov Yuav Tsum Muaj

Vim tias muaj cov kab mob ulcerogenic acetylsalicylic acid nyob rau hauv kev sib xyaw ntawm Acecardol, kev siv cov tshuaj no yog contraindicated rau cov menyuam yaus hnub nyoog qis dua 18 xyoo thiab nyob rau hauv cov neeg mob uas muaj cov kabmob zoo li no sau tseg hauv keeb kwm ntawm tus kabmob:

raum lossis mob siab raum tsis ua haujlwm,
ntxiv los ntshav
los ntshav hauv cov kab mob ntawm cov hnyuv,
mob ntsws asthma ua pa nrog polyposis qhov ntswg,
erosive puas tsuaj rau lub plab zom mov.

Tsuas tshuaj thiab tswj hwm

Cov lus qhia rau kev siv muaj cov sijhawm teem rau kev noj cov ntsiav tshuaj ntawm Acecardol. Tshaj li qhov qhia ntawm kev noj tshuaj thiab kev hloov pauv ntawm kev siv tshuaj tsis pom zoo yam tsis muaj kev pom zoo los ntawm kws kho mob. Cov tshuaj yuav tsum nkag mus rau txoj hnyuv tsis muaj kev puas tsuaj ntawm lub cev ntawm daim nyias nyias; rau qhov no, nws yuav tsum nqos mus tag nrho thiab ntxuav nrog dej kom huv si. Acecardol yuav tsum noj ua ntej noj mov. Txhawm rau tiv thaiv qhov tsis zoo ntawm lub mucosa, cov ntsiav tshuaj tuaj yeem muab ntxuav nrog kua dej alkaline.

Thaum noj Acecardol rau kev tiv thaiv kab mob, cov lus qhia hauv qab no yuav tsum tau ua raws:

Kev mob tshwm sim thiab contraindications Acekardol

Raws li kev txheeb xyuas thiab cov ntawv tshaj tawm, Acecardol tuaj yeem ua rau ntau yam kev phiv.

Los ntawm lub plab zom mov: xeev siab, kub siab, ntuav, mob epigastric, mob rau ntawm lub plab mos ntawm lub plab thiab duodenum, perforated mob ntawm lub plab thiab duodenum, plab hnyuv los ntshav, hloov lub siab ua haujlwm nrog kev ua haujlwm ntawm hepatic transaminases.
Los ntawm cov kab mob hemopoietic: lub sijhawm teem ntawm ASA tau ua ke nrog kev pheej hmoo los ntshav vim yog cov nyhuv inhibitory ntawm ASA ntawm platelet sib sau ua ke, ua kom ntshav khov.
Kev tsis haum tshuaj: tawv nqaij ua pob khaus, khaus, urticaria, Quincke's edema, rhinitis, o rau lub qhov ntswg ntawm lub qhov ntswg, mob plawv ntswj, nrog rau kev tsis haum tshuaj, suav nrog kev poob siab anaphylactic.
Los ntawm cov txheej txheem ua pa: bronchospasm.
Los ntawm sab ntawm lub hauv nruab nrab hauv lub paj hlwb: kiv taub hau, tsis muaj zog, hnov lus, mob taub hau, tinnitus.

Ntawm cov kev mob tshwm sim, los ntshav thaum txhuam koj cov hniav, ntswg qhov ntswg tiv thaiv keeb kwm yav dhau los ntawm kev kub siab yog feem ntau sau tseg. Ntau tus neeg mob yws ntawm lub siab tom qab noj Acecardol.

Txawm hais tias koj muaj kev txhawj xeeb txog kev phiv, koj yuav tsum tsis txhob txwv tsis pub noj tshuaj Acekardol. Tham nrog koj tus kws kho mob yog tias koj tuaj yeem tso mob acetylsalicylic acid lossis hloov nws nrog lwm yam. Cov xov xwm kev kho mob txawv teb chaws ceeb toom tias thawj thawj zaug tom qab tshem tawm txoj kev noj tshuaj aspirin txhua hnub hauv cov neeg mob, feem ntau txhaws ntawm cov hlab ntshav nrog cov ntshav txhaws, mob plawv thiab ntshav ischemic vim tias "cuam tshuam".

Noj ntau dhau

Cov tsos mob ntawm kev siv ntau dhau ntawm mob hnyav: xeev siab, ntuav, tinnitus, hnov tsis hnov lus, kiv taub hau, pom kev txawv txav, tsis meej pem.

Kev Kho Mob: kom tsawg dua.

Kev noj tshuaj ntau dua ntawm Acecardol hawv cuam tshuam rau txoj hlab ntsws, mob plawv, mob raum tsis ua haujlwm, hyperglycemia thiab ntshav qab zib tsawg. Yog tias muaj kev haus ntau dhau, muaj kev pheej hmoo loj ntawm kev ua tiav ntawm lub plab zom mov thiab txoj hnyuv los ntshav.

Thaum muaj kev noj tshuaj ntau dhau ntawm qhov mob hnyav, cov kev coj ua hauv qab no: kev mus pw hauv tsev kho mob tshwj xeeb hauv chav haujlwm tshwj xeeb rau kev kho mob thaum muaj xwm txheej ceev - pais plab lav, kev txiav txim siab ntawm cov kua qaub-tshuav nyiaj li cas, alkaline thiab yuam alkaline diuresis, hemodialysis, kev tswj hwm ntawm cov kev daws teeb meem, ua kom hluav ncaig hluav taws xob, kho cov tsos mob.

Cov Tshuaj Tiv Thaiv:

mob hnyuv los ntshav,
yaig, mob plab zom kiav txhab,
bronchial hawb pob hauv cov theem ntawm exacerbation thiab kev zam txim,
hemorrhagic diathesis,
mob plawv tsis ua hauj lwm
cov me nyuam tsis tau muaj 18 xyoo,
polyposis ntawm paranasal sinuses thiab qhov ntswg.

Nws yog nruj me ntsis txwv tsis pub noj tshuaj Acekardol, analogues thiab kev npaj zoo sib xws hauv lub sijhawm ntawm cev xeeb tub (tag nrho lub sijhawm ntawm cev xeeb tub) thiab pub niam mis. Tsis tas li ib tug contraindication yuav suav hais tias ib tug neeg rhiab heev rau acetylsalicylic acid thiab ntu nyob rau hauv cov tshuaj muaj pes tsawg leeg, nyob rau hauv kev lactose.

Contraindicated nyob rau hauv kev mob siab raum tsis ua haujlwm (creatinine tshem tawm (CC) tsawg dua 30 ml / min). Nrog kev ceev faj thiab tsuas yog nyob rau hauv kev saib xyuas ntawm tus kws tshaj lij, ib qho tshuaj yog tawm rau lub raum tsis ua haujlwm (CC ntau dua 30 ml / min).

Acecardol analogs, cov npe

Cov tshuaj ntawm Acecardol yog cov tshuaj (npe):

Tseem Ceeb - cov lus qhia rau kev siv Acecardol, tus nqi thiab kev tshuaj xyuas tsis suav rau cov analogues thiab tsis tuaj yeem raug coj los ua cov lus qhia rau kev siv tshuaj ntawm cov tshuaj zoo sib xws lossis siv tau. Txhua txhua teem sijhawm kho yuav tsum ua los ntawm kws kho mob. Thaum hloov Acecardol nrog tshuaj tiv thaiv kab mob, nws yog ib qho tseem ceeb kom tau txais tswv yim tshwj xeeb, koj yuav tsum tau hloov kho chav kho mob, siv tshuaj, thiab lwm yam. Tsis txhob siv tshuaj rau tus kheej!

Kev tshuaj xyuas ntawm cov kws kho mob txog tshuaj Acekardol yog qhov zoo. Cov kws kho mob tau hais tias cov tshuaj yog qhov zoo rau kev tiv thaiv kev rov mob plawv, mob nkees, ntxiv rau kev mob plab tom qab kev phais mob thiab ua haujlwm zoo ntawm lawv txoj haujlwm.

Cov neeg mob uas tau ua lub luag haujlwm ntawm txoj kev kho tau hais tias yog tias koj tsis zom cov ntsiav tshuaj, ces yuav tsis muaj qhov tsis xis nyob hauv plab tom qab noj. Qhov no muab cov enteric txheej ntawm cov ntsiav tshuaj daim ntawv ntawm cov tshuaj. Qhov loj tshaj plaws tsuas yog ua raws li kev siv tshuaj uas koj tus kws kho mob pom zoo. Tsis tas li, qhov tseeb ntawm qhov muaj txiaj ntsig zoo hauv kev tiv thaiv thiab kev kho mob ntshav txhaws tau pom los ntawm cov neeg mob.