Augmentin rau menyuam yaus - thaum twg thiab kuv tuaj yeem noj tshuaj li cas?

Thov, ua ntej yuav Augmentin, kev ncua 200 mg + 28,5 mg / 5 ml, lub raj mis 70 ml, tshawb xyuas cov ntaub ntawv nrog nws nrog cov ntaub ntawv ntawm lub vev xaib ntawm cov khw lossis qhia cov kev cai tshwj xeeb ntawm tus qauv tshwj xeeb nrog tus thawj tswj haujlwm ntawm peb lub tuam txhab!

Cov ntaub ntawv qhia ntawm lub xaib tsis yog pej xeem kev pom zoo. Lub chaw tsim khoom muaj txoj cai los hloov cov qauv tsim, tsim qauv thiab ntim khoom. Cov duab ntawm cov khoom hauv cov duab tau tshaj tawm hauv phau ntawv teev npe ntawm lub xaib yuav txawv ntawm cov qauv.

Cov ntaub ntawv ntawm tus nqi ntawm cov khoom tau hais hauv phau ntawv qhia rau ntawm lub xaib yuav txawv qhov tseeb ntawm ib tus neeg thaum lub sijhawm tso daim ntawv txiav txim rau cov khoom lag luam.

Chaw tsim tshuaj paus

5 ml ntawm qhov kev ua tiav tas muaj:

Cov tshuaj nquag: amoxicillin (hauv daim ntawv ntawm trihydrate) - 200 mg, clavulanic acid (hauv daim ntawv ntawm cov ntsev potassium) - 28,5 mg.

Cov neeg mob: xanthan ntawm cov pos hniav - 12.5 mg, aspartame - 12.5 mg, succinic acid - 0.84 mg, colloidal silicon dioxide - 25 mg, hypromellose - 79.65 mg, txiv kab ntxwv tsw 1 - 15 mg, txiv kab ntxwv tsw 2 - 11.25 mg, raspberry tsw - 22,5 mg, Lub teeb phoov tsw - 23,75 mg, silicon dioxide - txog 552 mg.

Pharmacological kev txiav txim

Amoxicillin yog cov tshuaj tua kab mob ntau tshaj ib nrab hnub nrog kev ua si tiv thaiv ntau yam kab mob gram-positive thiab gram-tsis zoo. Nyob rau tib lub sijhawm, amoxicillin tiv thaiv kev puas tsuaj los ntawm β-lactamases, thiab yog li ntawd kev ua si spectrum ntawm amoxicillin tsis txuas ntxiv rau cov kab mob me me uas tsim cov enzyme no.

Clavulanic acid, ib qho β-lactamase inhibitor yam ntxwv ntawm kev siv rau penicillins, muaj peev xwm tsis muaj peev xwm tiv thaiv ntau yam ntawm β-lactamases pom muaj nyob rau hauv penicillin thiab cephalosporin resistant microorganisms.

Clavulanic acid muaj txiaj ntsig tiv thaiv plasmid β-lactamases, uas feem ntau ua rau cov kab mob tiv thaiv kab mob, thiab tsis tshua muaj txiaj ntsig tiv thaiv chromosomal β-lactamases ntawm hom 1 uas tsis tiv thaiv los ntawm clavulanic acid.

Qhov muaj cov clavulanic acid nyob hauv kev npaj Augmentin® tiv thaiv amoxicillin los ntawm kev puas tsuaj los ntawm cov enzymes - act-lactamases, uas tso cai rau nthuav cov tshuaj tua kab mob ntawm amoxicillin.

Cov hauv qab no yog hauv kev ua haujlwm hauv vitro ntawm amoxicillin nrog clavulanic acid.

Cov kab mob feem ntau cuam tshuam rau kev sib xyaw ntawm amoxicillin nrog clavulanic acid

Gram-positive aerobes: Bacillus anthracis, Enterococcus faecalis, Listeria monocytogenes, Nocardia asteroides, Streptococcus pyogenes1,2, Streptococcus agalactiae1,2, Streptococcus spp. (lwm beta hemolytic streptococci) 1,2, Staphylococcus aureus (nkag siab rau methicillin) 1, Staphylococcus saprophyticus (rhiab rau methicillin), Staphylococcus spp. (coagulase-negative, rhiab rau methicillin).

Gram-negative aerobes: Bordetella pertussis, Haemophilus influenzae1, Helicobacter pylori, Moraxella catarrhalis1, Neisseria gonorrhoeae, Pasteurella multocida, Vibrio cholerae.

Lwm yam: Borrelia burgdorferi, Leptospira icterohaemorrhagiae, Treponema pallidum.

Gram-positive anaerobes: Clostridium spp., Peptococcus niger, Peplostreptococcus magnus, Peptostreptococcus micros, Peptostreptococcus spp.

Gram-negative anaerobes: Bacteroides fragilis, Bacteroides spp., Capnocytophaga spp., Eikenella corrodens, Fusobacterium nucleatum, Fusobacterium spp., Porphyromonas spp., Prevotella spp.

Cov kab mob rau cov uas yuav tiv taus cov tshuaj amoxicillin nrog clavulanic acid yog qhov yuav tshwm sim

Gram-negative aerobes: Escherichia coli1, Klebsiella oxytoca, Klebsiella pneumoniae1, Klebsiella spp., Proteus mirabilis, Proteus vulgaris, Proteus spp., Salmonella spp., Shigella spp.

Gram-positive aerobes: Corynebacterium spp., Enterococcus faecium, Streptococcus pneumoniae1,2, Streptococcus pawg Viridans2.

Cov kab mob uas ib txwm muaj peev xwm tiv thaiv kev sib txuas ntawm amoxicillin nrog clavulanic acid

Gram-negative aerobes: Acinetobacter spp., Citrobacter freundii, Enterobacter spp., Hafnia alvei, Legionella pneumophila, Morganella morganii, Providencia spp., Pseudomonas spp., Serratia spp., Stenotrophomonas maltophilia, Yersinia.

Lwm yam: Chlamydia mob ntsws, Chlamydia psittaci, Chlamydia spp., Coxiella burnetti, Mycoplasma spp.

1 - rau cov kab mob sib kis, kev soj ntsuam kev ua tau zoo ntawm kev sib xyaw ntawm amoxicillin nrog clavulanic acid tau pom nyob hauv kev tshawb fawb.

2 - hom kab mob ntawm cov hom kab no tsis tsim β-lactamases. Kev nkag siab nrog amoxicillin monotherapy qhia zoo ib yam li kev nkag siab zoo rau kev sib xyaw ntawm amoxicillin nrog clavulanic acid.

Cov kab mob kis tau los ntawm cov tshuaj lom neeg lub cev:

• Kev kis mob ntawm cov pa sab saud thiab cov kabmob ENT (xws li mob tonsillitis, mob ntsws, mob otitis media), feem ntau tshwm sim los ntawm Streptococcus pneumoniae, Haemophilus influenzae *, Moraxella catarrhalis *, Streptococcus pyogenes,
• Cov kab mob ua pa tsawg dua: exacerbations ntawm kev mob ntsws ntev, lobar mob ntsws thiab mob ntsws, feem ntau los ntawm Streptococcus pneumoniae, Haemophilus influenzae * thiab Moraxella catarrhalis * (tshwj tsis yog rau ntsiav tshuaj 250 mg / 125 mg),
• Kev kis tus mob Urogenital: cystitis, urethritis, pyelonephritis, kis mob rau poj niam lub cev, ua feem ntau los ntawm hom kab mob Enterobacteriaceae tsev neeg (feem ntau Escherichia coli *), Staphylococcus saprophyticus thiab hom kab mob ntawm genus Enterococcus,
• Gonorrhea tshwm sim los ntawm Neisseria gonorrhoeae * (tshwj tsis yog 250 mg / 125 mg ntsiav tshuaj),
• Kev kis mob ntawm daim tawv nqaij thiab cov nqaij mos, feem ntau tshwm sim los ntawm Staphylococcus aureus *, Streptococcus pyogenes thiab hom ntawm cov genus Bacteroides *,
• Kev kis mob ntawm cov pob txha thiab pob qij txha: osteomyelitis, feem ntau tshwm sim los ntawm Staphylococcus aureus *, yog tias tsim nyog, kev kho mob ntev,
• Cov kab mob Odontogenic, piv txwv li, mob qog, odontogenic, maxillary sinusitis, mob hniav ntau heev nrog nthuav cellulite (rau cov ntsiav tshuaj 500 mg / 125 mg lossis 875 mg / 125 mg),
• Lwm yam kev sib xyaw ua ke (piv txwv, septic rho menyuam tawm, sepsis tom qab, mob se rau lub plab) yog ib feem ntawm kev kho mob kauj ruam (rau cov ntsiav tshuaj 250 mg / 125 mg lossis 500 mg / 125 mg, lossis 875 mg / 125 mg).

* - Cov tib neeg sawv cev ntawm cov kab mob tshwj xeeb tsim tawm β-lactamase, uas ua rau lawv tsis muaj qhov tsis haum rau amoxicillin.

Kev kis mob tshwm sim los ntawm cov kab mob me me uas nkag rau amoxicillin tuaj yeem kho nrog Augmentin®, vim tias amoxicillin yog ib qho ntawm nws cov khoom xyaw tseem ceeb. Augmentin® tseem tseem tau qhia rau kev kho mob sib xyaw ua ke los ntawm cov kab mob me me nkag rau amoxicillin, nrog rau cov kab mob me me uas ua β-lactamase, rhiab rau kev sib xyaw ntawm amoxicillin nrog clavulanic acid.

Qhov rhiab ntawm cov kab mob mus rau kev sib xyaw ua ke ntawm amoxicillin nrog clavulanic acid nws txawv nyob ntawm thaj av thiab dhau sijhawm. Qhov tsim nyog, cov ntaub ntawv hais txog qhov chaw hauv zos yuav tsum tau coj mus rau hauv qhov chaw. Yog tias tsim nyog, kuaj cov kab mob microbiological yuav tsum tau sau thiab txheeb xyuas rau tus kab mob bacteriological rhiab.

Cev xeeb tub thiab lactation

Hauv kev tshawb fawb ntawm kev ua me nyuam hauv cov tsiaj, qhov ncauj thiab kev tswj hwm ntawm Augmentin® tsis ua rau muaj teebmeem teratogenic.

Hauv txoj kev tshawb fawb ib zaug hauv cov poj niam nrog lub cev ua ntej lub cev xoos xoos, nws tau pom tias kev siv tshuaj kho mob muaj feem cuam tshuam nrog kev pheej hmoo ntawm necrotizing enterocolitis hauv cov menyuam mos yug tshiab. Zoo li txhua yam tshuaj, Augmentin® tsis pom zoo rau siv thaum cev xeeb tub, tshwj tsis yog tias muaj kev cia siab rau tus niam tshaj qhov muaj feem yuav ua rau muaj menyuam hauv plab.

Cov tshuaj Augmentin® tuaj yeem siv thaum pub mis. Dhau ntawm qhov muaj peev xwm ntawm kev tsim muaj mob raws plab lossis ua paug rau ntawm cov kua qog ua rau lub qhov ncauj ua kab mob cuam tshuam nrog kev nkag mus ntawm cov nyiaj ntawm cov tshuaj yeeb dej caw ntawm cov tshuaj no mus rau niam mis, tsis muaj lwm yam kev tsis zoo tshwm sim hauv cov menyuam mos niam mis. Yog tias muaj qhov tshwm sim tsis zoo hauv cov menyuam mos uas tseem noj niam mis, nws yuav tsum tau tsum tsis txhob pub niam mis.

Cov Yuav Tsum Muaj

• Cov tshuaj tiv thaiv tsis haum rau amoxicillin, clavulanic acid, lwm yam tshuaj, tshuaj tua kab mob beta-lactam (piv txwv li penicillins, cephalosporins) hauv anamnesis.
• Yav dhau los lub sijhawm daj ntseg lossis lub siab ua kom lub siab ua haujlwm thaum siv amoxicillin nrog clavulanic acid nyob hauv keeb kwm.
• Cov menyuam yaus hnub nyoog qis dua 12 xyoos thiab lub cev hnyav dua li 40 kg (rau cov ntsiav tshuaj 250 mg / 125 mg lossis 500 mg / 125 mg, lossis 875 mg / 125 mg).
• Cov menyuam yaus lub hnub nyoog txog li 3 hlis (rau cov hmoov siv rau kev npaj ncua ntawm kev ncua ntawm qhov ncauj 200 mg / 28.5 mg thiab 400 mg / 57 mg).
• Cov raum tsis ua haujlwm (CC ≤ 30 ml / min) - (rau cov ntsiav tshuaj 875 mg / 125 mg, rau hmoov rau kev ncua rau kev tswj hwm qhov ncauj 200 mg / 28.5 mg thiab 400 mg / 57 mg).
• Phenylketonuria (rau hmoov rau lub qhov ncauj tawm).

Ceev faj: lub siab ua haujlwm tsis zoo.

Sab sij huam

Cov xwm txheej tsis zoo uas tau nthuav tawm hauv qab no yog teev raws li kev puas tsuaj rau cov kabmob thiab cov nruab nrog cev thiab qhov ntau zaus tshwm sim. Qhov ntau zaus ntawm kev tshwm sim tau txiav txim siab raws li hauv qab no: ntau zaus (≥1 / 10), feem ntau (≥ 1/100,

Cov ntau zaus tau tsim nyob rau hauv lub hauv paus ntawm kev tshawb fawb soj ntsuam cov tshuaj thiab kev soj ntsuam tom qab soj ntsuam.

Kev kis mob thiab cov kab mob parasitic: feem ntau - mob tawv nqaij ntawm daim tawv nqaij thiab cov qog ua kua.

Nyob rau ib feem ntawm cov ntshav thiab lymphatic system: tsis tshua muaj - thim rov qab leukopenia (suav nrog neutropenia) thiab thim rov qab thrombocytopenia, tsis tshua muaj tshwm sim - thim rov qab agranulocytosis thiab thim rov qab hemolytic anemia, lub caij nyoog ntawm prothrombin lub sijhawm thiab los ntshav, mob ntshav tsis txaus, eosinophilia, thrombocytosis.

Ntawm feem ntawm kev tiv thaiv kab mob hauv lub cev: tsis tshua muaj tshwm sim - mob hlwb, phiv tshuaj tiv thaiv kev tsis haum tshuaj, cov tsos mob zoo ib yam li kev mob ntshav tawm tsam, kev tsis haum tshuaj vasculitis.

Los ntawm cov kab mob hauv lub cev: tsis tuaj yeem - kiv taub hau, mob taub hau, tsis tshua muaj tshwm sim - thim rov qab hyperactivity, convulsions (txiav tau tuaj yeem tshwm sim hauv cov neeg mob uas tsis muaj lub raum tsis ua haujlwm, zoo li hauv cov neeg uas tau txais tshuaj ntau heev), insomnia, ntxhov siab, kev coj tus cwj pwm Cov.

Los ntawm cov hnyuv hauv plab: cov neeg laus: feem ntau - zawv plab, feem ntau - xeev siab, ntuav, menyuam - feem ntau - raws plab, xeev siab, ntuav, tag nrho cov pej xeem: xeev siab yog feem ntau pom thaum noj cov tshuaj loj. Yog tias tom qab pib noj cov tshuaj muaj qhov tsis tsim nyog tshwm sim los ntawm txoj hnyuv, lawv tuaj yeem tshem tawm yog tias koj noj cov tshuaj thaum pib noj mov. Cuam tshuam - lub plab zom mov, tsis tshua muaj tshwm sim - cov tshuaj tua kab mob ntsig txog kev mob plab los ntawm kev siv tshuaj tua kab mob (suav nrog rau cov mob ua paug thiab cov mob plab), dub nplaig "muaj nplaig", mob plab, mob plab. Hauv cov menyuam yaus, thaum ua ntawv thov kev ncua, qhov cuam tshuam ntawm txheej txheej txheej hniav txha hniav laus yog qhov tsis tshua pom muaj. Kev tu xyuas hniav yuav pab tiv thaiv kom tsis txhob muaj qhov sib txawv ntawm tus hniav txha hniav laus, vim nws txaus los txhuam koj cov hniav.

Los ntawm daim siab thiab mob mus rau hauv lub biliary: ua tsis xws luag - muaj kev tawm ntawm qhov nruab nrab ntawm ACTi / lossis ALT (pom hauv cov neeg mob tau txais beta-lactam siv tshuaj tua kab mob, tab sis nws qhov tseem ceeb hauv cov chaw kho mob tsis paub), muaj tsawg kawg - kab mob siab thiab mob cholestatic (qhov tshwm sim no tau sau tseg thaum kho nrog lwm tus penicillins thiab cephalosporins), kev nce siab hauv cov concentration ntawm bilirubin thiab alkaline phosphatase. Kev phiv tshuaj los ntawm daim siab raug pom muaj feem ntau hauv cov txiv neej thiab cov neeg laus laus thiab yuav cuam tshuam nrog kev kho lub sij hawm ntev. Cov xwm txheej tsis zoo no tsis tshua pom muaj hauv cov menyuam yaus.

Cov cim npe thiab cov tsos mob feem ntau tshwm sim thaum lossis tom qab tas kev kho, txawm li cas los xij qee zaum qee zaum lawv yuav tsis tshwm sim rau ntau lub lis piam tom qab kev kho tiav. Cov xwm txheej tsis zoo yog cov thim rov qab. Kev phiv tshuaj los ntawm daim siab tuaj yeem yog qhov hnyav, muaj qee qhov tsis tshua muaj neeg ceeb toom kev ua kom tuag taus. Yuav luag txhua qhov teeb meem no, cov no yog cov neeg muaj mob loj los sib deev lossis cov neeg tau txais cov tshuaj muaj kabmob hepatotoxic tib lub sijhawm

Nyob rau ib feem ntawm daim tawv nqaij thiab cov nqaij mos subcutaneous: ua haujlwm ntxau - tawm pob, khaus, urticaria, tsis tshua muaj - erythema multiforme, tsis tshua muaj tshwm sim - Stevens-Johnson syndrome, tshuaj lom epidermal necrolysis, kev ua kom lub cev ua paug rau mob, ua kom muaj kab mob pheev pheev kom zoo.

Yog tias muaj tawv nqaij tsis haum, kev kho nrog Augmentin® yuav tsum tsis ua mus ntxiv.

Los ntawm lub raum thiab mob txeeb zig: tsis tshua muaj tshwm sim - interstitial nephritis, crystalluria, hematuria.

Kev sib txuam

Kev siv ua ke ib txhij ntawm cov tshuaj Augmentin® thiab probenecid tsis pom zoo. Probenecid txo cov tubular ua ke ntawm amoxicillin, thiab yog li ntawd, tib lub sijhawm siv cov tshuaj Augmentin® thiab probenecide tuaj yeem ua rau nce ntxiv thiab mob siab rau hauv cov ntshav concentration ntawm amoxicillin, tab sis tsis muaj clavulanic acid.

Kev siv tib txhij ntawm allopurinol thiab amoxicillin tuaj yeem ua rau muaj kev pheej hmoo ntawm cov tawv nqaij ua xua. Tam sim no, tsis muaj cov ntaub ntawv hauv cov ntawv sau ntawm kev siv tib lub sijhawm ntawm kev sib xyaw ntawm amoxicillin nrog clavulanic acid thiab allopurinol. Penicillins tuaj yeem ua kom qeeb ntawm kev siv tshuaj methotrexate los ntawm lub cev los ntawm kev txwv tsis pub nws cov tubular tso pa, yog li ntawd, tib lub sijhawm siv Augmentin® thiab methotrexate tuaj yeem ua rau kom muaj kuab lom ntawm methotrexate.

Zoo li lwm yam tshuaj tua kab mob, Augmentin® tuaj yeem cuam tshuam rau lub plab hnyuv microflora, ua rau txo qis ntawm cov tshuaj estrogen los ntawm kev mob plab thiab txo qis kev ua tau zoo ntawm kev sib xyaw ua ke ntawm lub qhov ncauj.

Cov ntawv nyeem tau piav qhia qhov tsis tshua muaj qhov tshwm sim ntawm kev nce qib hauv kev thoob ntiaj teb (MHO) hauv cov neeg mob uas siv cov acenocoumarol lossis warfarin thiab amoxicillin. Yog tias tsim nyog, kev tswj hwm tib lub sijhawm ntawm Augmentin® npaj nrog anticoagulants, lub sijhawm prothrombin lossis MHO yuav tsum ua tib zoo saib xyuas thaum sau ntawv lossis tsum tsis npaj rau Augmentin; kev npaj kho;

Yuav ua li cas coj, chav kawm ntawm kev tswj hwm thiab ntau npaum li cas

Cov tshuaj noj rau lub cev yog tsim tshwj xeeb raws lub hnub nyoog, lub cev qhov hnyav, lub raum kev ua haujlwm ntawm tus neeg mob, nrog rau qhov mob hnyav heev.

Txhawm rau kom zoo thiab txo qis kev phiv los ntawm lub plab zom mov, Augmentin® pom zoo kom noj thaum pib noj mov.

Qhov kawm tsawg kawg ntawm cov tshuaj tua kab mob yog 5 hnub.

Txoj kev kho yuav tsum tsis txhob txuas ntxiv ntev dua 14 hnub yam tsis muaj tshuaj xyuas qhov xwm txheej kho mob.

Yog tias tsim nyog, nws muaj peev xwm los ua kev kho mob staged (thaum pib txoj kev kho, kev tswj hwm kev coj ntawm cov tshuaj nrog kev hloov mus rau tom kev tswj hwm qhov ncauj).

Cov neeg loj thiab menyuam yaus hnub nyoog 12 xyoos lossis hnyav dua 40 kg lossis ntau dua

1 ntsiav tshuaj ntawm 250 mg / 125 mg 3 zaug / hnub (rau kev kis mob me txog rau mob hnyav), lossis 1 ntsiav tshuaj ntawm 500 mg / 125 mg 3 zaug / hnub, lossis 1 ntsiav tshuaj ntawm 875 mg / 125 mg 2 zaug / hnub, lossis 11 ml ntawm kev ncua ntawm 400 mg / 57 mg / 5 ml 2 zaug / hnub (uas yog sib npaug rau 1 ntsiav tshuaj ntawm 875 mg / 125 mg).

2 ntsiav tshuaj ntawm 250 mg / 125 mg tsis sib npaug rau 1 ntsiav tshuaj ntawm 500 mg / 125 mg.

Cov menyuam yaus hnub nyoog 3 hlis txog 12 xyoos nrog lub cev hnyav dua 40 kg

Cov tshuaj yog sau tseg hauv daim ntawv ntawm kev ncua rau kev tswj hwm ntawm qhov ncauj.

Kev suav qhov ntsuas yog ua raws li hnub nyoog thiab lub cev qhov hnyav, qhia hauv mg / kg lub cev qhov hnyav / hnub (xam raws li amoxicillin) lossis hauv ml ntawm kev ncua.

Qhov ntau yam pauv ntawm qhov kev ncua 125 mg / 31.25 mg hauv 5 ml - 3 zaug / hnub txhua 8 teev

Qhov ntau yam ntawm kev ncua 200 mg / 28.5 mg hauv 5 ml lossis 400 mg / 57 mg hauv 5 ml - 2 zaug / hnub txhua 12 teev.

Cov kev xav noj ntau npaum li cas thiab kev tswj hwm pes tsawg yog hais hauv qab no:

Kev ntau dua ntawm kev nkag mus - 3 zaug / hnub, ncua 4: 1 (125 mg / 31.25 mg hauv 5 ml):

• Tsawg koob tshuaj - 20 mg / kg / hnub.
• Kev txhaj tshuaj ntau - 40 mg / kg / hnub.

Kev ntau ntau ntawm kev tswj hwm - 2 zaug / hnub, kev ncua 7: 1 (200 mg / 28.5 mg hauv 5 ml lossis 400 mg / 57 mg hauv 5 ml):

• Kev txhaj tshuaj qis - 25 mg / kg / hnub.
• Kev txhaj tshuaj ntau - 45 mg / kg / hnub.

Kev txhaj tshuaj qis ntawm Augmentin® yog siv los kho cov kab mob ntawm daim tawv nqaij thiab cov nqaij mos, nrog rau cov mob tonsillitis.

Kev txhaj tshuaj ntau ntawm Augmentin® yog siv los kho cov kab mob xws li otitis media, sinusitis, mob kis qis dua ntawm txoj hlab ntsws thiab mob txeeb zig, kis kab mob ntawm cov pob txha thiab pob qij txha.

Muaj cov ntaub ntawv kuaj mob tsis txaus kom pom zoo siv cov tshuaj Augmentin® ntawm koob tshuaj ntau dua 40 mg / kg / hnub hauv 3 koob tshuaj (4: 1 ncua kev kawm) hauv cov menyuam yaus hnub nyoog qis dua 2 xyoos.

Cov menyuam txij thaum yug mus txog 3 hlis

Vim lub cev tsis muaj nuj nqi ntawm qhov muaj nuj nqi zoo kawg ntawm lub raum, qhov tshuaj pom zoo ntawm Augmentin® (xam rau amoxicillin) yog 30 mg / kg / hnub hauv 2 faib koob tshuaj 4: 1.

Kev siv qhov kev ncua 7: 1 (200 mg / 28.5 mg hauv 5 ml lossis 400 mg / 57 mg hauv 5 ml) tsis pom zoo rau cov neeg no.

Cov menyuam yug ua ntej

Tsis muaj cov lus qhia hais txog qhov muab tshuaj.

Cov neeg laus cov neeg mob

Tsis tas yuav txhaj ib koob. Hauv cov neeg mob laus uas lub raum lub raum tsis ua haujlwm, qhov koob tshuaj yuav tsum tau kho raws li cov lus qhia rau cov neeg laus uas lub raum tsis ua haujlwm.

Cov neeg mob uas lub raum tsis ua hauj lwm zoo

Kev hloov pauv koob yog nce raws li qhov siab tshaj plaws uas tau pom zoo ntawm amoxicillin thiab raug kwv yees QC cov txiaj ntsig.

Ntsiav tshuaj 250 mg + 125 mg lossis 500 mg + 500 mg:

• KK> 30 ml / min - kev kho ntawm kev muab tshuaj yog tsis tas yuav tsum tau ua.
• KK 10-30 ml / min - 1 tab. 250 mg + 125 mg 2 zaug / hnub lossis 1 tab. 500 mg + 125 mg (rau kev sib kis mob me txog rau mob) 2 zaug / hnub.
• QC

Ncua Sijhawm 4: 1 (125 mg / 31.25 mg hauv 5 ml):

• KK> 30 ml / min - kev kho ntawm kev muab tshuaj yog tsis tas yuav tsum tau ua.
• KK 10-30 ml / min - 15 mg / 3.75 mg / kg 2 zaug / hnub, qhov ntau tshaj yog 500 mg / 125 mg 2 zaug / hnub.
• QC

875 mg + 125 mg ntsiav tshuaj thiab 7: 1 ncua kev kawm (200 mg / 28.5 mg hauv 5 ml lossis 400 mg / 57 mg hauv 5 ml) yuav tsum tsuas yog siv rau cov neeg mob CC> 30 ml / min, uas tsis muaj kev kho qhov tshuaj yuav tsum tau.

Feem ntau, yog tias ua tau, kev kho mob rau cov niam txiv yuav tsum yog qhov zoo dua.

Cov neeg mob Hemodialysis

Kev hloov pauv koob tshuaj yog ua raws li qhov siab tshaj plaws ntawm kev tso cai ntawm amoxicillin: 2 tab. 250 mg / 125 mg hauv ib koob tshuaj txhua 24 teev, lossis 1 daim pib. 500 mg / 125 mg nyob rau hauv ib koob txhua 24 teev, lossis ncua kev ncua ntawm 15 mg / 3.75 mg / kg 1 zaug / hnub.

Ntsiav tshuaj: thaum lub caij ntu mob hemodialysis, ib qho ntxiv 1 koob tshuaj (ib ntsiav tshuaj) thiab 1 koob tshuaj ntxiv (ib ntsiav tshuaj) tom qab kawg ntawm kev lim ntshav (kom them rau qhov txo qis hauv cov ntshav ntau ntawm amoxicillin thiab clavulanic acid).

Raug tshem tawm: ua ntej kev kho mob hemodialysis, ib koob tshuaj ntxiv ntawm 15 mg / 3.75 mg / kg yuav tsum tau muab tshuaj. Txhawm rau kom rov qab ua dua qhov kev coj ua ntawm cov tshuaj nquag Augmentin® hauv cov ntshav, ntxiv ib koob thib ob ntawm 15 mg / 3.75 mg / kg yuav tsum tau qhia tom qab kev sib tham ntawm hemodialysis.

Cov neeg mob uas muaj lub siab ua haujlwm tsis zoo

Txoj kev kho yog nqa tawm nrog ceev faj, daim siab ua haujlwm tseem raug saib xyuas tsis tu ncua. Tsis muaj cov ntaub ntawv txaus los kho qhov tshuaj ntau npaum li cas hauv pawg neeg mob no.

Cov kev cai npaj rau ntawm kev npaj rau kev ncua ntawv

Qhov kev ncua yog npaj tam sim ua ntej siv thawj zaug.

Ncua (125 mg / 31.25 mg hauv 5 ml): kwv yees li 60 ml ntawm cov dej rhaub kom txias rau chav sov yuav tsum tau ntxiv rau lub raj mis hmoov, tom qab ntawd kaw lub raj mis nrog lub hau thiab co kom txog thaum cov hmoov yaj tag, ua kom lub raj mis sawv ntsug li 5 feeb rau ua kom tiav kev sib tua. Tom qab ntawd ntxiv dej rau lub cim rau ntawm lub raj mis thiab co lub raj mis dua. Hauv tag nrho, kwv yees li 92 ml ntawm dej yog xav tau los npaj qhov kev ncua. Lub raj mis yuav tsum tau co kom zoo ua ntej txhua qhov kev siv. Txhawm rau kom raug tshuaj, qhov ntsuas yuav tsum raug siv, uas yuav tsum tau ntxuav zoo nrog dej tom qab siv txhua zaus. Tom qab kev nrawm, qhov kev ncua yuav tsum khaws cia tsis pub dhau 7 hnub hauv lub tub yees, tab sis tsis khov.

Rau cov menyuam yaus hnub nyoog qis dua 2 xyoos, kev ntsuas ib leeg ntawm qhov raug ncua ntawm kev npaj Augmentin® tuaj yeem nchuav ib nrab nrog dej.

Ncua (200 mg / 28.5 mg hauv 5 ml lossis 400 mg / 57 mg hauv 5 ml): ntxiv kwv yees li 40 ml ntawm dej rhaub kom txias mus rau chav tsev kub mus rau lub raj mis hmoov, tom qab ntawd kaw lub raj mis taub hau thiab co kom txog thaum cov hmoov yaj tag. Tso kom vial sawv ntsug li 5 feeb kom paub meej kev ua kom tiav. Tom qab ntawd ntxiv dej rau lub cim rau ntawm lub raj mis thiab co lub raj mis dua. Hauv tag nrho, kwv yees li 64 ml ntawm dej yog xav tau los npaj qhov kev ncua. Lub raj mis yuav tsum tau co kom zoo ua ntej txhua qhov kev siv. Txhawm rau kom raug qhov tseeb ntawm cov tshuaj, siv lub hau ntsuas lossis cov koob txhaj tshuaj, uas yuav tsum tau ntxuav nrog dej zoo tom qab siv txhua zaus. Tom qab kev nrawm, qhov kev ncua yuav tsum khaws cia tsis pub dhau 7 hnub hauv lub tub yees, tab sis tsis khov.

Rau cov menyuam yaus hnub nyoog qis dua 2 xyoos, kev ntsuas ib leeg ntawm qhov ncua kev ncua ntawm Augmentin® kev npaj yuav tuaj yeem xeb nrog dej hauv qhov sib piv ntawm 1: 1.

Noj ntau dhau

Cov tsos mob: lub plab zom mov cov tsos mob thiab dej-electrolyte tsis txaus yuav tshwm sim.Amoxicillin crystalluria tau piav qhia, hauv qee kis ua rau kev loj hlob ntawm lub raum tsis ua haujlwm.

Qhov ncauj keev tuaj yeem tshwm sim rau cov neeg mob uas lub raum lub raum tsis ua haujlwm, nrog rau cov neeg uas tau txais tshuaj ntau heev.

Kev Kho Mob: mob plab zom mov - kev kho mob kom zoo, them nyiaj tshwj xeeb rau kev ua kom dej-electrolyte sib npaug. Yog tias muaj kev noj ntau dhau, amoxicillin thiab clavulanic acid tuaj yeem tshem tawm cov ntshav tawm los ntawm hemodialysis.

Cov txiaj ntsig ntawm kev soj ntsuam ib txwm muaj nrog 51 tus menyuam ntawm lub chaw tso tshuaj lom tau qhia tias kev tswj hwm ntawm amoxicillin ntawm koob tshuaj tsawg dua 250 mg / kg tsis tau ua rau cov tsos mob tseem ceeb thiab tsis tas yuav ua kom mob plab.

Cov lus qhia tshwj xeeb

Ua ntej pib kho nrog Augmentin®, nws yog ib qho tsim nyog yuav tsum tau sau cov ncauj lus kom ntxaws txog kev kho mob yav dhau los ntsig txog kev tiv thaiv kab mob siab rau penicillins, cephalosporins lossis lwm yam kev ua xua.

Cov mob hnyav, thiab qee zaum kuj ua rau neeg tuag taus, ua kom lub cev tsis haum tshuaj (qhov tsis haum tshuaj muaj txiaj ntsig) rau cov penicillins tau piav qhia. Txoj kev pheej hmoo ntawm cov kev tawm tsam zoo li no yog qhov siab tshaj plaws rau cov neeg mob uas muaj keeb kwm ntawm kev tsis haum lub cev rau penicillins. Thaum muaj kev fab tshuaj tsis haum, nws yog ib qho tsim nyog yuav tsum tsis mus kho nrog Augmentin® thiab pib kho lwm txoj kev kho kom haum. Yog tias muaj teeb meem rau qhov mob nyhav dhau los, yuav tsum muab tshuaj rau epinephrine sai sai. Kev kho cov pa oxygen, kev tswj hwm kev tswj hwm ntawm GCS thiab kev pabcuam hauv airway patency, suav nrog kev nkag mus ntxiv, kuj tseem yuav tsum ua.

Kev teem sijhawm rau cov tshuaj Augmentin® tsis pom zoo rau cov neeg xav tias muaj tus mob mononukpeosis, vim tias nyob hauv cov neeg mob tus mob amoxicillin tuaj yeem ua rau mob pob khaus zoo li pob khaus, uas ua rau muaj kev cuam tshuam ntau ntawm kev kuaj mob.

Kev kho mob mus ntev nrog Augmentin® qee zaum ua rau muaj kev tawm tsam ntau ntawm cov kab mob tsis haum.

Hauv qhov dav dav, Augmentin tole tau pom zoo zoo thiab muaj cov tshuaj toxicity qis ntawm txhua tus penicillins.

Lub sijhawm kho mob ntev nrog Augmentin®, nws raug nquahu kom ntsuas qee lub sijhawm ua haujlwm ntawm lub raum, mob siab thiab ntshav.

Txhawm rau kom txo qis kev phiv los ntawm kev mob plab hnyuv, cov tshuaj yuav tsum noj thaum noj mov.

Hauv cov neeg mob uas tau txais kev sib xyaw ntawm amoxicillin nrog clavulanic acid ua ke nrog indirect (qhov ncauj) anticoagulants, nyob rau hauv cov xwm txheej tsis tshua muaj, kev nce prothrombin lub sijhawm (nce hauv MHO) tau tshaj tawm. Nrog rau kev sib koom tes ntawm kev tiv thaiv kabmob (qhov ncauj) anticoagulants nrog kev sib xyaw ntawm amoxicillin nrog clavulanic acid, kev saib xyuas ntawm cov ntsuas tseem ceeb yog qhov tsim nyog. Yuav kom tswj tau qhov xav tau ntawm qhov ncauj ua kom lub ntsej muag, qhov ntau npaum yuav tsum tau hloov kho.

Hauv cov neeg mob uas lub raum tsis ua haujlwm, qhov tshuaj ntawm Augmentin® yuav tsum tau txo kom haum raws li qhov ntsuas ntawm qhov tsis taus.

Hauv cov neeg mob uas txo qis diuresis, feem ntau tsis tshua muaj, kev loj hlob ntawm crystalluria tau tshaj tawm, feem ntau nrog kev siv tshuaj yaj yeeb. Thaum lub sijhawm tswj hwm ntawm amoxicillin koob tshuaj ntau, nws raug nquahu kom noj cov kua txaus thiab tswj cov diuresis kom txaus los txo qhov muaj feem ntawm kev tsim cov amoxicillin muaju.

Noj cov tshuaj Augmentin® sab hauv ua rau cov ntsiab lus ntawm amoxicillin nyob rau hauv cov zis, uas tuaj yeem ua rau cov lus tsis muaj qhov tsis zoo hauv kev txiav txim siab cov piam thaj hauv cov zis (piv txwv, kev kuaj Benedict, ib qho kev sim Feling). Hauv qhov no, nws raug nquahu kom siv cov txheej txheem glucose oxidant rau kev txiav txim siab cov ntsiab lus ntawm cov piam thaj hauv cov zis.

Kev tu xyuas hniav yuav pab tiv thaiv kom tsis txhob ua kom pom cov hniav, txij li txhuam koj cov hniav tau txaus.

Cov ntsiav tshuaj yuav tsum tau siv tsis pub dhau 30 hnub txij li lub sijhawm qhib pob ntawm laminated lev ntawv ci.

Kev quav yeeb quav tshuaj thiab quav yeeb tshuaj

Tsis pom muaj kev quav yeeb tshuaj, quav tshuaj thiab kev tsis haum tshuaj cuam tshuam nrog kev siv tshuaj Augmentin® tau pom.

Cuam tshuam rau kev muaj peev xwm tsav tsheb thiab tswj cov tshuab

Txij li thaum cov tshuaj yuav ua rau kiv taub hau, nws yog ib qho tsim nyog ceeb toom rau cov neeg mob txog kev ceev faj thaum tsav tsheb lossis ua haujlwm nrog cov tshuab txav.

Lub sijhawm twg ntawm cov tshuaj tua kab mob Augmentin?

Cov tshuaj tua kab mob Augmentin hais txog kev npaj ua ke ntawm cov khoom cua thiab cov tshuaj tua kab mob ntawm cov tshuaj penicillin. Nws suav nrog:

• amoxicillin trihydrate,
• poov tshuaj clavulanate (clavulanic acid).

Cov tshuaj muaj nyob rau hauv ntau daim ntawv qhia: hmoov rau kev txhaj tshuaj, ntsiav tshuaj, phoov thiab cov tshuaj qhuav rau qhov kev npaj ncua. Cov me nyuam tsis tau muaj 12 xyoos raug sam fwm los yog ncua ntawv. Cov ntawv no tau zam zoo txawm tias me nyuam, txawm li cas los xij, nws tsis tuaj yeem tshem tawm tag nrho kev txhim kho ntawm kev fab tshuaj. Qhov tseeb no yuav tsum raug coj los txiav txim thaum muab tshuaj rau cov menyuam yaus (saib xyuas lub cev lub cev teb tom qab thawj koob).

Augmentin - kev qhia rau siv rau menyuam yaus

Siv cov tshuaj kom nruj hauv kev siv tshuaj kho mob. Tus kws kho mob yaus qhia tias ntau npaum li cas, kev noj tshuaj npaum li cas los ntawm Augmentin, qhov ntsuas kev siv uas yog raws li nram no:

• cov txheej txheem sib kis ntawm cov pa sab saud, suav nrog cov kab mob ntawm pob ntseg, lub caj pas thiab lub qhov ntswg (mob sinusitis, tonsillitis, otitis media),
• muaj cov txheej txheem mob hnyav nyob hauv cov nruab nrog ua pa - kab mob ntsws, mob ntsws,
• kab mob ntawm cov kab mob ntawm lub tso zis - urethritis, pyelonephritis, cystitis,
• kis ntawm daim tawv nqaij thiab cov nqaij mos,
• cov txheej txheem sib kis hauv cov nqaij pob txha.

Augmentin - contraindications

Cov tshuaj tau txais txiaj ntsig zoo los ntawm menyuam mos, tab sis nws tsis tuaj yeem siv tas li. Cov kws kho mob coj cov cim no mus rau hauv tus account thaum sau ntawv rau Augmentin rau menyuam yaus, cov lus contraindications rau kev siv uas muaj raws li hauv qab no:

• muaj lub cev tsis haum rau lub tshuaj,
• penicillin tshuaj tua kab mob kev tsis txaus siab,
• muaj qhov tshwm sim ntawm kev daj ntseg tiv thaiv keeb kwm yav dhau los ntawm kev siv yav dhau los ntawm kev sib xyaw ntawm amoxicillin nrog clavulanic acid.

Nws tseem yog qhov tseem ceeb cais cais contraindications rau txhua daim ntawv ntawm cov tshuaj:

• cov ntsiav tshuaj ntawm 250 mg thiab ntau dua tsis tau sau rau cov menyuam yaus hnub nyoog qis dua 12 xyoos nrog lub cev qhov hnyav tsawg dua 40 kg,
• hmoov rau kev ncua yog contraindicated hauv cov menyuam mos txog li 3 hlis thiab menyuam yaus nrog phenylketonuria.

Augmentin rau cov menyuam yaus, ncua kev kawm - noj ntau npaum

Kev qhia Augmentin, yuav ua li cas los laij cov tshuaj rau tus menyuam - kws kho mob piav qhia meej rau niam. Qhov ntau npaum li cas yog muab xam rau ntawm tus kheej thiab nyob ntawm hom mob, theem ntawm txheej txheem pathological, hnub nyoog thiab hnyav ntawm tus menyuam. Thaum xam xyuas qhov yuav tsum tau noj tshuaj npaum li cas, tsuas yog cov ntsiab lus ntawm amoxicillin sodium yuav tsum coj mus rau hauv tus lej - tus nqi ntawm cov tshuaj nquag muaj nyob hauv ib hom tshuaj twg. Rau Augmentin, nws yog qhia ntawm ntim thiab lub raj mis nrog tshuaj (hauv mg).

Augmentin 125, ncua kev kawm - muab tshuaj rau cov menyuam yaus

Thaum Augmentin kev ncua tsis pub dhau, raug muab qhov ntau rau cov menyuam yaus tau tsim los ua tib zoo xav txog lub cev qhov hnyav ntawm tus menyuam. Qhov ntsuas no yog qhov tseem ceeb thaum txiav txim qhov ntau ntawm cov tshuaj tua kab mob. Nws tsim nyog sau cia tias thaum muaj hnub nyoog tib yam, menyuam yaus tuaj yeem muaj qhov hnyav sib txawv, yog li kev teem caij cov tshuaj raws lub hnub nyoog tsis raug. Hauv cov ntsiab lus no, Augmentin yog siv rau cov menyuam yaus. Qhov muab xam ntawm cov tshuaj yog raws li nram no:

• cov me nyuam qis dua 1 xyoos (lub cev hnyav 2-5 kg) - 1.5-2.5 ml 3 zaug ib hnub,
• cov me nyuam 1-5 xyoos (6-9 kg) - 5 ml peb zaug ib hnub,
• cov me nyuam 6–9 xyoos (19-28 kg) - 15 ml 3 zaug ib hnub,
• cov me nyuam 10-12 xyoos (29-39 kg) - 20 ml peb zaug ib hnub.

Augmentin 200, ncua kev kawm - muab tshuaj rau cov menyuam yaus

Augmentin 200 rau cov menyuam yaus yog qhov muaj ntau npaum. Hauv cov ntsiab lus no, cov tshuaj tuaj yeem raug kho rau menyuam mos. Kev sib txuam loj heev ntawm cov tshuaj nquag yuav txo qis qhov zaus ntawm kev noj tshuaj. Thaum sau daim ntawv tshuaj rau Augmentin 200, kev muab tshuaj rau cov menyuam yaus yog xam raws li hauv qab no:

• cov menyuam yaus txog 1 xyoos - 1.5-2.5 ml ib hnub ob zaug,
• cov me nyuam 1-5 xyoos - 5 ml ntawm kev ncua 2 zaug hauv ib hnub,
• cov me nyuam 6-9 xyoos - 15 ml 2 zaug ib hnub.

Augmentin 400 - ntau npaum rau cov menyuam

Qhov ntau kawg ntawm cov tshuaj Augmentin 400 (kev ncua rau cov menyuam yaus) yog siv rau hauv kev kho mob ntawm cov menyuam yaus laus zog. Nyob rau tib lub sijhawm, xav tau siv ntau zaus txo cov tshuaj tsawg dua - nws tau muab 2 zaug ib hnub tom qab 12 teev. Thaum sau ntawv los ntawm Augmentin rau 400 tus menyuam, cov kws kho mob pom zoo kom ua raws li cov tshuaj hauv qab no:

• cov me nyuam 6–9 xyoos - 7.5 ml ntawm kev ncua,
• thaum 10-12 xyoos - 10 ml 2 zaug ib hnub.

Yuav muab Augmentin rau cov menyuam li cas?

Sib tham txog yuav ua li cas coj Augmentin rau cov menyuam yaus, cov kws kho mob siab mloog zoo rau qhov yuav tsum tau txais kev ncaj ncees rau kev noj tshuaj. Ua ntej siv, hmoov yuav yaj nrog cov kua uas yuav tsum muaj (kua rhaub). Rau qhov yooj yim, daim ntawv lo ntawm Augmentin lub raj mis rau menyuam yaus muaj qhov cim ntawm qib uas nws yuav tsum tau ntim dej. Tom qab ntawd, kaw cov hau ntswj me ntsis thiab sib tov cov tshuaj kom huv, muab nws ci li 2 feeb.

Lawv siv cov Augmentin tshuaj tua kab mob rau cov menyuam yaus hauv kev nruj me ntsis raws li cov ntawv kho mob. Rau kev txhaj tshuaj yooj yim, siv lub ntsuas ntsuas uas los nrog cov khoom siv, lossis ntaub nqus dej. Txhawm rau txo qis qhov kev pheej hmoo ntawm cov tshuaj ntawm lub plab zom mov, cov tshuaj tau muab rau tus menyuam ob peb feeb ua ntej noj mov. Tom qab siv txhua yam tshuaj, lub khob ntsuas tau muab ntxuav kom huv, qhuav thiab rov qab siv dua.

Augmentin - kev mob tshwm sim rau menyuam yaus

Ncua kev kawm rau cov me nyuam Augmentin qee kis muaj peev xwm ua kev mob tshwm sim thaum siv. Thaum lawv tshwm sim, cov tshuaj nres, thiab kws kho mob hauv tsev kho mob paub txog qhov tshwm sim. Nrog rau kev mob tshwm sim ntau ntawm Augmentin, yuav tsum tau hloov cov tshuaj. Ntawm cov kev qhia no, peb tuaj yeem paub qhov txawv:

• kev puas tsuaj ntawm txoj hnyuv (mob plab, raws plab, xeev siab thiab ntuav),
• kev cuam tshuam ntawm lub cev tsis muaj zog - kev ua xua,
• ua txhaum ntawm cov ntshav circulatory system - tsim ntawm ntshav txhaws,
• ntxeev siab ntawm daim siab - kab mob siab,
• kev nyuaj siab ntawm lub hauv nruab nrab lub paj hlwb - mob taub hau, kiv taub hau, nriaj,
• kev cuam tshuam ntawm daim tawv nqaij - erythema, khaus.

Dab tsi tuaj yeem hloov Augmentin rau menyuam?

Nrog kev ua tsis tau zoo ntawm Augmentin tshuaj rau cov menyuam yaus, txoj kev loj hlob ntawm cov tshuaj tiv thaiv los ntawm lub cev me rau nws txoj kev nkag, niam feem ntau xav txog yam uas Augmentin tuaj yeem hloov nrog. Coob tus naj npawb analogues tau nthuav tawm ntawm cov tshuaj khw, yog li nws yuav yooj yim rau xaiv cov tshuaj uas haum rau tus menyuam. Hauv qhov no, nws yog qhov yuav tsum tau ua raws li cov lus pom zoo tau txais los ntawm tus kws kho menyuam yaus uas tau kho mob:

1. Nyeem cov lus qhia.
2. Coj mus rau hauv lub hnub nyoog ntawm tus menyuam.
3. Saib seb qhov qhia ntau npaum li cas thiab kev noj tshuaj npaum li cas.
4. Nrog rau txhua qhov pauv hloov ntawm txoj kev nyob zoo ntawm tus menyuam, qhia rau tus kws khomob.

Ntawm cov tshuaj nrog amoxicillin siv los kho cov menyuam yaus, cov tshuaj feem ntau:

• Amoxiclavkviktab,
• Amoxil-k
• Zoopercin,
• Camox Ceeb
• Amoxiplus,
• Baktoklav,
• Vampilox.

Augmentin (kev ncua, ntsiav tshuaj, hmoov) - nqe

Tus nqi ntawm ntau hom ntawm Augmentin hauv chaw muag tshuaj ntawm Lavxias lub nroog nws txawv raws li hauv qab no:

• Augmentin hmoov rau kev npaj ncua ntawm 125 / 31.25 - 118 - 161 rubles,
• Augmentin hmoov rau kev npaj ncua ntawm 200 / 28.5 - 126 - 169 rubles,
• Augmentin hmoov rau kev npaj ncua 400-57 - 240 - 291 rubles,
• Augmentin EU hmoov rau kev npaj rau kev ncua ntawm 600 / 42.9 - 387 - 469 rubles,
• Ntsiav tshuaj 250/125, 20 daim - 246-301 rubles,
• Ntsiav tshuaj 875/125, 14 daim - 334 - 430 rubles,
• Augmentin SR 1000 / 62.5 ntsiav tshuaj, 28 daim - 656 - 674 rubles,
• Hmoov rau kev daws rau kev txhaj tshuaj 1000/200 - 1797 - 2030 rubles.

Augmentin thaum cev xeeb tub thiab lactation

Hauv kev tshawb fawb ntawm kev ua me nyuam hauv cov tsiaj, qhov ncauj thiab kev tswj hwm ntawm Augmentin® tsis ua rau muaj teebmeem teratogenic.

Hauv kev tshawb fawb ib zaug hauv cov poj niam nrog lub cev ua ntej lub cev puas, nws tau pom tias kev kho nrog prophylactic nrog Augmentin® tej zaum cuam tshuam nrog kev pheej hmoo ntawm necrotizing enterocolitis hauv cov menyuam mos yug tshiab.

Zoo li txhua yam tshuaj, Augmentin® tsis pom zoo rau siv thaum cev xeeb tub, tshwj tsis yog muaj kev cia siab rau tus niam tshaj qhov muaj feem yuav ua rau muaj menyuam hauv plab.

Cov tshuaj Augmentin® tuaj yeem siv thaum pub mis.Dhau ntawm qhov muaj peev xwm ntawm kev tsim muaj mob raws plab lossis ua paug rau ntawm cov kua qog ua rau lub qhov ncauj ua kab mob cuam tshuam nrog kev nkag mus ntawm cov nyiaj ntawm cov tshuaj yeeb dej caw ntawm cov tshuaj no mus rau niam mis, tsis muaj lwm yam kev tsis zoo tshwm sim hauv cov menyuam mos niam mis.

Zoo li feem ntau cov tshuaj tua kab mob ntawm pawg penicillin, amoxicillin, muab faib rau hauv cov ntaub so ntswg ntawm lub cev, tseem nkag mus rau hauv niam cov kua mis. Ntxiv mus, kab qis ntau ntawm clavulanic acid tej zaum yuav pom nyob rau hauv cov mis nyuj.

Txawm li cas los xij, tsis muaj kev cuam tshuam loj hauv lub tsev kho mob los ntawm tus mob ntawm tus me nyuam yog sau tseg. Muaj qee kis, kev sib xyaw ntawm clavulanic acid nrog amoxicillin tuaj yeem ua rau mob raws plab thiab / lossis candidiasis (mob ntsws) ntawm cov qog ua kua rau hauv qhov ncauj kab noj hniav hauv menyuam.

Augmentin belongs rau cov qeb ntawm cov tshuaj pub mis pub mis. Yog tias, txawm li cas los xij, tiv thaiv keeb kwm ntawm niam txoj kev kho mob nrog Augmentin, tus me nyuam muaj qee qhov tshwm sim tsis zoo, kev pub mis niam yog tso tseg.

Kev tshawb nrhiav tsiaj pom tau tias cov tshuaj nquag ntawm Augmentin muaj peev xwm nkag mus rau hauv hemato-placental (GPB) barrier. Txawm li cas los xij, tsis muaj qhov tshwm sim tsis zoo rau kev loj hlob ntawm tus menyuam hauv plab.

Ntxiv mus, teratogenic teebmeem tau tsis tuaj nrog niam txiv kev coj noj coj ua thiab tshuaj noj ntawm qhov ncauj.

Kev siv cov Augmentin hauv cov poj niam cev xeeb tub tuaj yeem ua rau txoj kev loj hlob ntawm necrotizing enterocolitis (NEC) hauv menyuam mos.

Zoo li txhua lwm yam tshuaj, Augmentin tsis pom zoo rau cov poj niam cev xeeb tub. Thaum cev xeeb tub, nws siv tau rau qee qhov xwm txheej, raws li kws kho mob qhov kev ntsuas, qhov txiaj ntsig rau tus poj niam muaj ntau tshaj qhov txaus ntshai rau nws tus menyuam.

Augmentin Dosage (rau cov neeg laus thiab cov menyuam yaus)

Ib qho ntawm cov lus nug feem ntau ntawm tus neeg mob yog cov lus nug txog kev noj tshuaj ua ntej lossis tom qab noj mov. Nyob rau hauv rooj plaub ntawm Augmentin, kev noj tshuaj yog ze ze rau kev noj mov. Nws suav tias yog qhov zoo dua rau noj cov tshuaj tam sim ua ntej noj mov.

Firstly, nws muab kev nqus zoo dua ntawm cov tshuaj nquag ntawm lawv txoj hnyuv, thiab, qhov thib ob, nws muaj peev xwm txo tau qhov mob tsis haum plab tsis zoo los ntawm kev mob plab, yog tias tom kawg tshwm sim.

Yuav ua li cas los xam cov koob tshuaj ntawm Augmentin

Yuav noj cov tshuaj Augmentin rau cov neeg laus thiab menyuam yaus li cas, nrog rau nws txoj kev kho mob, nyob ntawm seb tus kab mob me me yog dab tsi, vim li cas nws cuam tshuam rau cov tshuaj tua kab mob, mob hnyav thiab cov yam ntxwv ntawm tus kab mob, kev ua kom thaj tsam ntawm tus mob sib kis, lub hnub nyoog thiab qhov hnyav ntawm tus neeg mob, nrog rau noj qab nyob zoo npaum li cas nws tus neeg mob raum.

Lub sijhawm tiv thaiv ntawm cov chav kho yog nyob ntawm seb tus neeg mob lub cev teb li cas rau kev kho mob.

Augmentin ntsiav tshuaj: cov lus qhia rau kev siv

Ua raws li cov ntsiab lus ntawm cov tshuaj yeeb dej caw hauv lawv, Augmentin ntsiav tshuaj raug pom zoo rau cov neeg mob laus kom noj raws li cov qauv hauv qab no:

• Augmentin 375 mg (250 mg 125 mg) - ib peb zaug ib hnub. Hauv cov tshuaj no, cov tshuaj tau qhia rau kis tus mob uas tshwm sim hauv cov mob me lossis mob me mus rau mob hnyav. Thaum muaj mob hnyav, suav nrog mob ntev thiab rov tshwm sim, ntau dua qhov tau muab tshuaj.
• Cov ntsiav tshuaj 625 mg (500 mg 125 mg) - ib peb zaug ib hnub.
• Cov ntsiav tshuaj 1000 mg (875 mg 125 mg) - ib qho ib hnub ob zaug.

Cov koob tshuaj yog qhov raug rau cov neeg tuaj kho mob uas lub raum lub raum tsis ua haujlwm.

Augmentin CP 1000 mg / 62.5 mg cia cov ntsiav tshuaj tso tawm tsuas yog pub rau cov neeg mob hnub nyoog 16 xyoo rov hauv. Cov koob tshuaj zoo yog ob ntsiav tshuaj ib hnub ob zaug.

Yog tias tus neeg mob tsis tuaj yeem nqos tag nrho cov ntsiav tshuaj, nws muab faib ua ob kab raws txoj kab txhaum. Ob qho tib si ob leeg tau coj tib lub sijhawm.

Rau cov neeg mob raum uas muaj lub raum, cov tshuaj tau hais tawm tsuas yog hauv qhov xwm txheej ntawm Reberg tus nqi ntau dua 30 ml ib feeb (uas yog, thaum kho rau qhov ntau npaum li cas tsis tas yuav).

Hmoov rau cov tshuaj rau kev txhaj tshuaj: cov lus qhia rau kev siv

Raws li cov lus qhia, txoj kev daws teeb meem yog txhaj rau hauv txoj leeg: los ntawm dav hlau (qhov koob tshuaj yuav tsum tau txhaj tshuaj hauv 3-4 feeb) lossis los ntawm cov txheej txheem dej (lub sijhawm ntawm Txoj kev lis ntshav yog los ntawm ib nrab ntawm ib teev mus rau 40 feeb). Txoj kev daws tsis tau xav kom tau txhaj tshuaj rau hauv cov leeg.

Cov qauv muab rau ib tus neeg mob laus yog 1000 mg / 200 mg. Nws raug nquahu kom nkag mus rau nws txhua yim teev, thiab rau kev kis mob nrog cov teeb meem - txhua rau lossis rau plaub teev (raws li kev qhia).

Cov tshuaj tua kab mob hauv daim ntawv ntawm kev daws 500 mg / 100 mg lossis 1000 mg / 200 mg yog tau sau tseg los tiv thaiv kev txhim kho ntawm cov txheej txheem sib kis tau tom qab kev phais. Nyob rau hauv rooj plaub thaum lub sijhawm ua haujlwm tsawg tshaj li ib teev, nws txaus los qhia kev noj tshuaj ntawm Augmentin 1000 mg / 200 mg rau tus neeg mob ib zaug ua ntej tshuaj loog.

Yog tias nws cia siab tias qhov kev ua haujlwm yuav kav ntev dua li ib teev, txog plaub koob ntawm 1000 mg / 200 mg tau muab rau tus neeg mob nyob rau hnub dhau los rau 24 teev.

Kev ncua Augmentin: cov lus qhia rau kev siv

Cov lus qhia rau kev siv Augmentin rau menyuam yaus pom zoo kom teem sij hawm ncua ntawm 125 mg / 31.25 mg hauv koob tshuaj 2.5 txog 20 ml. Kev muaj txiaj ntsig ntau ntawm kev txais khoom - 3 thaum nruab hnub. Qhov ntim ntawm ib koob tshuaj nyob ntawm lub hnub nyoog thiab qhov hnyav ntawm tus menyuam.

Yog tias tus menyuam loj dua ob lub hlis ntawm hnub nyoog, ncua kev ncua 200 mg / 28.5 mg yog tau sau rau hauv koob tshuaj ib yam li 25 / 3.6 mg rau 45 / 6.4 mg rau 1 kg ntawm lub cev qhov hnyav. Cov koob tshuaj uas tau hais tseg yuav tsum muab faib ua ob zaug.

Qhov ncua kev kawm ntawv nrog rau qhov ntau npaum ntawm cov tshuaj 400 mg / 57 mg (Augmentin 2) yog qhia rau kev siv pib txij li xyoo. Nyob ntawm seb tus me nyuam muaj hnub nyoog thiab hnyav li cas, ib koob tshuaj nws txawv ntawm 5 mus rau 10 ml. Kev muaj txiaj ntsig ntau ntawm kev txais khoom - 2 thaum nruab hnub.

Augmentin EU yog pib txij 3 lub hlis hnub nyoog. Cov koob tshuaj zoo tshaj plaws yog 90 / 6.4 mg rau 1 kg ntawm lub cev qhov hnyav hauv ib hnub (qhov koob tshuaj yuav tsum tau muab faib ua 2 koob, khaws ib ntu 12-teev nruab nrab ntawm lawv).

Txog rau hnub no, cov tshuaj nyob rau hauv ntau npaum li cas cov tshuaj yog ib qho ntawm cov neeg sawv cev tshaj plaws rau kev kho mob tonsillitis.

Cov me nyuam Augmentin nrog angina yog tshuaj hauv koob tshuaj, uas tau txiav txim siab raws lub cev qhov hnyav thiab hnub nyoog ntawm tus me nyuam. Nrog angina rau cov neeg laus, nws raug nquahu kom siv Augmentin 875 125 mg peb zaug ib hnub.

Tsis tas li, lawv feem ntau nyiam rau kev teem caij Augmentin nrog mob pob txha caj qaum. Txoj kev kho yog pab ntxiv los ntawm kev ntxuav lub qhov ntswg nrog ntsev hiav txwv thiab siv cov tshuaj txau qhov ntswg xws li Rinofluimucil. Qhov tshuaj zoo ntau tshaj plaws rau kev mob ntsws: 875/125 mg 2 zaug ib hnub. Lub sijhawm ua haujlwm ntawm feem ntau yog 7 hnub.

Augmentin siv dav hauv kev xyaum tsiaj txhu. Vim qhov tseeb tias nws muaj menyuam yaus daim ntawv tso tawm - kua phoov, nws tuaj yeem siv tau los kho menyuam yaus rau ib xyoos xwb. Kev teeb tsa tshwj xeeb ua rau txais tos thiab qhov tseeb hais tias cov tshuaj muaj cov khoom qab ntxiag.

Rau cov menyuam yaus, tshuaj tua kab mob feem ntau kho mob angina. Qhov ntau npaum li cas ntawm kev ncua rau cov me nyuam yog txiav txim siab los ntawm lub hnub nyoog thiab qhov hnyav. Cov koob tshuaj zoo tshaj plaws tau muab faib ua ob koob, sib npaug 45 mg / kg ib hnub, lossis faib ua peb koob, koob tshuaj 40 mg / kg ib hnub.

Kev siv cov tshuaj rau cov menyuam yaus thiab caij nyoog ntau npaum li cas yog nyob ntawm daim ntawv ntau npaum li cas.

Rau cov menyuam yaus lub cev qhov hnyav tshaj 40 kg, Augmentin raug tso cai tib yam li cov neeg laus.

Augmentin phoov rau cov menyuam yaus txog li ib xyoos yog siv hauv qhov ntau ntawm 125 mg / 31.25 mg thiab 200 mg / 28.5 mg. Kev noj tshuaj ntawm 400 mg / 57 mg yog qhia rau cov menyuam yaus tshaj ib xyoos.

Cov menyuam yaus nyob rau hauv hnub nyoog 6-12 xyoo (hnyav dua 19 kg) raug tso cai siv ob qho kev ncua lossis Augmentin hauv cov ntsiav tshuaj. Kev muab tshuaj ntawm lub ntsiav tshuaj daim ntawv tshuaj yog raws li nram no:

• ib ntsiav tshuaj 250 mg 125 mg peb zaug ib hnub,
• ib ntsiav tshuaj 500 125 mg mg ib hnub ob zaug (daim ntawv ntau npaum li no yog txoj kev pom zoo).

Cov menyuam yaus hnub nyoog dhau 12 xyoos raug txwv kom noj ib ntsiav tshuaj ntawm 875 mg 125 mg ob zaug ib hnub.

Txhawm rau kom ntsuas qhov tseeb ntawm koob tshuaj Augmentin kev ncua rau cov menyuam muaj hnub nyoog qis dua 3 hlis, nws pom zoo kom ntaus cov lej nrog ib rab koob uas muaj qhov cim.Txhawm rau kom siv txoj kev siv ncua kev kawm ntawv hauv cov menyuam yaus hauv qab ob xyoos, nws tau tso cai kom cov kua dej nrog cov dej hauv qhov piv rau 50/50

Cov tshuaj Analogues ntawm Augmentin, uas yog nws hloov pauv chaw muag tshuaj, yog cov tshuaj Amoksiklav, Flemoklav Solyutab, Arlet, Rapiklav, Ekoklav.

Txhua daim ntawv tshuaj ntawm Augmentin muaj ob qho tshuaj xyaw - amoxicillin thiab clavulanic acid, yog li qhov ntau ntawm cov tshuaj tau qhia tsis yog los ntawm ib tus lej, tab sis los ntawm ob, piv txwv li, 400 mg 57 mg, thiab lwm yam.

Yog li, Augmentin nyob rau hauv daim ntawv ntawm hmoov rau kev npaj ntawm kev daws rau kev txhaj tshuaj muaj nyob rau hauv qhov ntau thiab tsawg ntawm 500 mg 100 mg thiab 1000 mg 200 mg. Qhov no txhais tau hais tias tom qab diluting hmoov nrog dej, ib qho kev daws teeb meem tau txais uas muaj 500 mg lossis 1000 mg ntawm amoxicillin thiab, ntsig txog, 100 mg thiab 200 mg ntawm clavulanic acid.

Hauv lub neej txhua hnub, cov ntaub ntawv tshuaj no feem ntau tau hais kom yooj yim "Augmentin 500" thiab "Augmentin 1000", siv ib daim duab uas nthuav tawm cov ntsiab lus ntawm amoxicillin thiab rho tawm ntau npaum li cas ntawm clavulanic acid.

Augmentin nyob rau hauv cov hmoov sau rau kev npaj ncua ntawm kev ncua rau kev tswj hwm qhov ncauj yog muaj nyob rau hauv peb qhov ntau: 125 mg 31.25 mg rau 5 ml, 200 mg 28.5 mg rau 5 ml thiab 400 mg 57 mg rau 5 ml.

Nyob rau hauv lub neej txhua hnub, kev tsim qauv ntawm tus nqi ntawm clavulanic acid feem ntau yog lawb tawm, thiab tsuas yog cov ntsiab lus ntawm amoxicillin yog qhia, vim tias qhov kev xam ntawm cov tshuaj noj yog ua tshwj xeeb rau cov tshuaj tua kab mob.

Txij li thaum ncua kev kawm Augmentin tau siv rau hauv cov menyuam tsis tau muaj 12 xyoos, feem ntau nws hu ua "menyuam yaus Augmentin." Raws li, qhov ntau npaum li cas ntawm lub txim yog hu ua menyuam mos. Qhov tseeb, qhov ntau npaum li cas ntawm kev ncua yog tus qauv thiab tej zaum yuav siv tau rau cov neeg laus uas lub cev tsis tshua muaj ceeb thawj, tab sis vim yog qhov tseem ceeb ntawm kev siv cov tshuaj no rau cov menyuam yaus, lawv hu ua menyuam yaus.

Augmentin EC muaj nyob rau hauv cov hmoov sau rau kev npaj ntawm kev ncua nyob rau hauv ib zaug tshuaj - 600 mg 42.9 mg rau 5 ml. Qhov no txhais tau hais tias 5 ml ntawm qhov kev ua tiav kev ua tiav muaj 600 mg ntawm amoxicillin thiab 42.9 mg ntawm clavulanic acid.

Augmentin SR muaj nyob rau hauv ntsiav tshuaj daim ntawv nrog rau kev noj tshuaj ib zaug ntawm cov tshuaj yeeb dej caw - 1000 mg 62.5 mg. Qhov no txhais tau hais tias ib ntsiav tshuaj muaj 1000 mg ntawm amoxicillin thiab 62.5 mg ntawm clavulanic acid.

Kev piav qhia ntawm daim ntawv tshuaj

Hmoov: dawb lossis yuav luag dawb, nrog tus yam ntxwv ntxhiab tsw. Thaum diluted, ib qho kev ncua ntawm dawb lossis yuav luag dawb yog tsim. Thaum sawv ntsug, ib qho dej dawb lossis dawb yuav luag nag lossis daus maj mam ua kom qeeb.

Cov ntsiav tshuaj, 250 mg 125 mg: zaj duab xis-coated los ntawm dawb mus yuav luag dawb, kheej li lub qw, nrog cov ntawv sau "AUGMENTIN" ntawm ib sab. Ntawm lub kink: los ntawm daj dawb rau yuav luag dawb.

Cov ntsiav tshuaj, 500 mg 125 mg: zaj duab xis-txheej los ntawm dawb mus yuav luag dawb hauv cov xim, oval, nrog cov ntawv sau ntxig "AC" thiab muaj kev pheej hmoo ntawm ib sab.

Cov ntsiav tshuaj, 875 mg 125 mg: zaj duab xis-txheej los ntawm dawb mus yuav luag dawb, oval, nrog cov tsiaj ntawv "A" thiab "C" ntawm ob sab thiab cov kab ua txhaum ntawm ib sab. Ntawm lub kink: los ntawm daj dawb rau yuav luag dawb.

Kev txheeb xyuas txog Augmentin

Kwv yees li 80 - 85% kev tshuaj xyuas ntawm Augmentin yog qhov zoo, uas yog vim qhov ua tau ntawm cov tshuaj hauv kev kho mob rau kev kho mob rau tib neeg. Hauv kev yuav luag txhua qhov kev tshuaj xyuas, tib neeg qhia tias muaj txiaj ntsig zoo ntawm cov tshuaj, vim tias nws muaj kev kho sai rau ib tus mob kis.

Txawm li cas los xij, nrog rau cov lus hais txog kev ua haujlwm ntawm Augmentin, tib neeg qhia tias muaj cov kev mob tshwm sim uas tsis zoo lossis lub siab tsis zoo. Nws yog qhov tshwm sim ntawm cov kev mob tshwm sim uas yog lub hauv paus rau cov seem 15 - 20% ntawm kev tshuaj xyuas tsis zoo sab laug txawm hais tias qhov kev ua tau zoo ntawm cov tshuaj.

Kev tshuaj xyuas ntawm cov ntsiav tshuaj thiab kev ncua rau cov me nyuam Augmentin feem ntau yog qhov zoo. Coob tus ntsuas cov tshuaj ua tshuaj tau txais txiaj ntsig zoo thiab ntseeg tau.

Ntawm cov chaw sib tham uas tib neeg qhia txog lawv cov kev xav ntawm qee yam tshuaj, cov qhab nia nruab nrab ntawm cov tshuaj tua kab mob yog 4,3-4.5 ntawm 5 lub ntsiab lus.

Cov kev tshuaj xyuas txog Augmentin tseg los ntawm leej niam ntawm cov menyuam yaus qhia tias qhov cuab yeej pab tau daws sai sai xws li cov kab mob xws li thaum yau xws li mob ntsws lossis tonsillitis. Ntxiv nrog rau qhov ua tau zoo ntawm cov tshuaj, cov niam kuj tseem nco qab nws cov qab ntxiag, uas cov menyuam nyiam.

Cov cuab yeej ua haujlwm kuj tseem muaj txiaj ntsig thaum cev xeeb tub. Txawm hais tias qhov tseeb hais tias qhov kev qhia tsis pom zoo kev kho mob nrog cov poj niam cev xeeb tub (tshwj xeeb tshaj yog nyob rau lub sijhawm 1 lub sijhawm), Augmentin feem ntau yog txiav txim siab thib 2 thiab thib 3 txiav.

Raws li cov kws kho mob, qhov loj tshaj plaws thaum kho nrog cov cuab yeej no yog soj ntsuam qhov ntau npaum li cas thiab ua raws txhua qhov kev pom zoo ntawm koj tus kws kho mob.

Kev ntsuas rau siv

Kev noj tshuaj rau lub cev yog tsim tshwj xeeb, nyob ntawm seb muaj hnub nyoog, hnyav lub cev, lub raum kev ua haujlwm ntawm tus neeg mob, nrog rau qhov mob hnyav npaum li cas.

Txhawm rau kom txo qis lub plab zom mov tuaj yeem cuam tshuam thiab txhawm rau txhawm rau nqus kom zoo, cov tshuaj yuav tsum tau noj thaum pib noj mov. Qhov kawm tsawg kawg ntawm cov tshuaj tua kab mob yog 5 hnub.

Txoj kev kho yuav tsum tsis txhob txuas ntxiv ntev dua 14 hnub yam tsis muaj tshuaj xyuas qhov xwm txheej kho mob.

Yog tias tsim nyog, nws yog qhov ua tau los ua cov kev kho mob stepwise (thawj kev tswj hwm kev siv tshuaj ntawm cov tshuaj nrog kev hloov mus rau tom kev tswj hwm qhov ncauj).

Nws yuav tsum nco ntsoov tias 2 tab. Augmentin®, 250 mg 125 mg tsis sib npaug rau 1 ntsiav tshuaj. Augmentin®, 500 mg 125 mg.

Cov neeg loj thiab menyuam yaus hnub nyoog 12 xyoos thiab laus dua lossis hnyav 40 kg lossis ntau dua. Nws raug nquahu kom siv 11 ml ntawm kev ncua ib ntus ntawm kev siv tshuaj ntawm 400 mg 57 mg hauv 5 ml, uas yog sib npaug rau 1 lub rooj. Augmentin®, 875 mg 125 mg.

1 tab. 250 mg 125 mg 3 zaug hauv ib hnub rau kev kis mob me me mus rau mob hnyav. Hauv kev kis mob hnyav (suav nrog kev mob raum thiab mob rov zoo li qub, mob ntsws thiab ib puag ncig kev ua pa ntawm txoj hlab ntsws), lwm txoj kev noj tshuaj ntawm Augmentin® yog kev pom zoo.

1 tab. 500 mg 125 mg 3 zaug ib hnub.

1 tab. 875 mg 125 mg 2 zaug ib hnub.

Cov menyuam hnub nyoog 3 hlis txog 12 xyoos nrog lub cev hnyav dua li 40 kg. Kev xam qhov tseeb yog nqa tawm raws li lub hnub nyoog thiab lub cev qhov hnyav, qhia hauv mg / kg / hnub lossis hauv ml ntawm kev ncua. Qhov koob tshuaj txhua hnub tau muab faib ua 3 koob tshuaj txhua 8 teev (125 mg 31.25 mg) lossis 2 koob tshuaj txhua 12 teev (200 mg 28.5 mg, 400 mg 57 mg). Cov tshuaj pom zoo ntau npaum li cas thiab kev tswj hwm pes tsawg zaus raug nthuav tawm hauv cov kab hauv qab no.

Augmentin Aug kev txhaj tshuaj ntau ntxiv (kev suav tshuaj rau amoxicillin)

Kev txhaj tshuaj qis ntawm Augmentin® raug pom zoo rau kev kho mob ntawm daim tawv nqaij thiab cov nqaij mos, nrog rau cov mob tonsillitis.

Kev txhaj tshuaj siab ntawm Augmentin High tau pom zoo rau kev kho mob ntawm cov kab mob xws li otitis media, sinusitis, kis mob qis qis ntawm txoj hlab ntsws thiab mob txeeb zig, mob pob txha thiab pob qij txha.

Muaj cov ntaub ntawv txhaj tshuaj tsis txaus kom pom zoo siv cov tshuaj Augmentin® hauv ib koob ntau dua 40 mg 10 mg / kg hauv 3 koob tshuaj (4: 1 ncua kev kawm) rau cov menyuam yaus hnub nyoog qis dua 2 xyoos.

Cov menyuam txij thaum yug mus txog 3 hlis. Vim lub cev tsis muaj nuj nqi ntawm qhov muaj nuj nqi zoo kawg ntawm lub raum, qhov tshuaj pom zoo ntawm Augmentin® (xam rau amoxicillin) yog 30 mg / kg / hnub hauv 2 faib koob tshuaj 4: 1.

Cov menyuam yug ntxov ntxov. Tsis muaj cov lus qhia hais txog qhov muab tshuaj.

Cov pab pawg neeg tshwj xeeb

Cov neeg laus cov neeg mob. Kev kho ntawm cov tshuaj ntau npaum li cas tsis tas yuav tsum tau ua; Hauv cov neeg mob laus uas lub raum lub raum tsis ua haujlwm, cov koob tshuaj uas tsim nyog rau cov neeg laus uas lub raum tsis ua haujlwm.

Cov neeg mob uas muaj lub siab ua haujlwm tsis zoo. Txoj kev kho yog nqa tawm nrog ceev faj, daim siab ua haujlwm tseem raug saib xyuas tsis tu ncua. Tsis muaj cov ntaub ntawv txaus los hloov lub tswv yim hloov cov koob tshuaj hauv cov neeg mob zoo li no.

Cov neeg mob uas lub raum tsis ua hauj lwm zoo.Kev kho ntawm cov tshuaj ntau npaum li cas yog raws li qhov siab tshaj plaws kev pom zoo ntawm amoxicillin thiab creatinine tshem tawm tus nqi.

Augmentin® ntau npaum cov tshuaj

Kev txhaj tshuaj Augmentin tseem qhia txog kev tiv thaiv thiab kho kev kis kab mob uas tuaj yeem tsim tau tom qab kev phais mob loj rau ntawm cov plab hnyuv ntawm lub plab zom mov, pelvis, lub taub hau, caj dab, raum, hauv kev phais plawv, thiab ntxiv rau tom qab cog ntshav ntawm prostheses rau hauv cov kabmob.

Cov lus qhia rau kev siv Ncua Kev Kawm Augmentin EU yog kev kho lub sijhawm luv luv ntawm cov kab mob hauv qab no tshwm sim los ntawm cov tshuaj tua kab mob-tiv thaiv cov microbes:

• Hauv neeg dua lossis mob otitis media,
• Mob caj pas
• Kev mob pob txha
• Lobar mob ntsws thiab mob ntsws,
• Kev kis mob ntawm daim tawv nqaij thiab cov nqaij mos (cellulitis, ua paug, phlegmon, rwj, panniculitis, mob viav vias).

Kev qhia rau kev siv tshuaj Augmentin SR yog lub sijhawm luv luv ntawm kev kho mob hauv qab no ua rau muaj mob los ntawm kev siv tshuaj tua kab mob:

• Mob ntsws yog tsis tsev kho mob
• Exacerbation ntawm mob ntsws ntev,
• Mob ntsws mob hlwb,
• Kev tiv thaiv ntawm kev sib kis mob hnyav tom qab kev kho hniav.

Cov ntsiav tshuaj yuav tsum tau nqos tag nrho, tsis yog zom, tsis tom thiab tsis ua puas ntsoog rau lwm txoj kev, tab sis ntxuav nrog ib qho me me

Ua ntej noj qhov ncua kev kawm ntawv, ntsuas qhov ntsuas yuav tsum tau siv uas siv lub ntsuas phoo tshwj xeeb lossis koob txhaj tshuaj zuam. Qhov kev ncua yog muab ntawm qhov ncauj, nqos tus ntsuas uas tsim nyog ntsuas los ntawm lub ntsuas ntsuas.

Cov menyuam yaus uas yog vim li cas tsis tuaj yeem haus cov dej raug tshem tawm, nws raug nquahu kom dilute nws nrog dej hauv qhov sib piv ntawm 1: 1, tom qab nchuav cov nyiaj tsim nyog los ntawm lub ntsuas ntsuas rau hauv lub khob lossis lwm lub khob. Tom qab siv tas, lub hau ntsuas lossis cov koob txhaj tshuaj yuav tsum yaug nrog cov dej huv.

Txhawm rau kom txo qis tsis xis nyob thiab phiv los ntawm lub plab zom mov, nws raug nquahu kom noj cov ntsiav tshuaj thiab muab ncua thaum pib noj mov. Txawm li cas los xij, yog tias qhov no ua tsis tau li cas los xij, tom qab ntawd cov ntsiav tshuaj tuaj yeem noj lub sijhawm twg los ntawm kev saib xyuas zaub mov, vim tias cov zaub mov tsis cuam tshuam rau qhov tshwm sim ntawm cov tshuaj.

Kev txhaj tshuaj Augmentin yog muab rau txoj leeg ntshav. Koj tuaj yeem hno cov tshuaj sib tov (los ntawm cov koob txhaj tshuaj) lossis infusion ("dropper"). Intramuscular cov thawj coj ntawm cov tshuaj tsis raug tso cai! Kev daws rau kev txhaj tshuaj yog npaj los ntawm hmoov tam sim ntawd ua ntej tswjhwm thiab tsis khaws txawm tias nyob hauv tub yees.

Kev tswj hwm ntawm cov ntsiav tshuaj thiab kev ncua, nrog rau kev tswj hwm ntawm cov dej ntawm Augmentin kev daws teeb meem, yuav tsum tau nqa tawm ntawm kev ua haujlwm tsis tu ncua. Piv txwv li, yog tias koj yuav tsum tau noj cov tshuaj ob zaug hauv ib hnub, ces koj yuav tsum tswj kev ncua 12 teev ib zaug nyob nruab nrab ntawm koob tshuaj.

Kho kev cuam tshuam

Augmentin muaj ib qho kev kho mob - tshuaj tua kab mob, vim nws muaj qhov cuam tshuam rau ntau yam kab mob sib kis uas ua rau muaj kab mob sib kis thiab mob ntawm cov kab mob genitourinary thiab ua pa,

thiab subcutaneous ntaub so ntswg, as Well as osteomyelitis,

Cov. Ntawd yog, Augmentin rhuav tshem cov kab mob uas ua rau mob cov kab mob no thiab, raws li, kho cov kis mob thiab cov kab mob.

Qhov muaj cov clavulanic acid nyob rau hauv Augmentin ua rau cov tshuaj muaj txiaj ntsig zoo, vim tias nws tso cai rau koj los nthuav cov spectrum ntawm kev ua ntawm amoxicillin thiab ua kom nws muaj txiaj ntsig tiv thaiv cov kab mob, uas, thaum raug rho tawm, siv cov tshuaj tua kab mob no, tiv taus nws.

Cov ntawv tso tawm, ntau yam thiab npe ntawm Augmentin

Tag nrho peb ntawm cov ntau ntawm Augmentin yog cov lag luam tawm ntawm tib cov tshuaj tua kab mob nrog tib cov kev cuam tshuam, kev ntsuas thiab cov cai ntawm kev siv.

Tsuas yog qhov sib txawv ntawm kev ua lag luam ntau yam ntawm Augmentin yog qhov ntau npaum ntawm cov tshuaj nquag thiab daim ntawv tso tawm (ntsiav tshuaj, ncua kev kawm, hmoov rau kev daws rau kev txhaj tshuaj).

Cov kev sib txawv no ua rau koj xaiv qhov zoo tshaj plaws ntawm cov tshuaj rau qee kis. Piv txwv li, yog tias ib tus neeg laus yog rau qee qhov tsis muaj peev xwm nqos tau Augmentin ntsiav tshuaj, nws tuaj yeem siv Augmentin EU kev ncua, thiab lwm yam.

Feem ntau, txhua hom tshuaj no tsuas yog hu ua "Augmentin", thiab txhawm rau paub meej qhov txhais tau meej, lawv tsuas yog ntxiv lub npe ntawm cov tshuaj thiab ntau npaum, piv txwv li, Augmentin raug ncua 200, Augmentin ntsiav tshuaj 875, thiab lwm yam.

Ntau hom Augmentin muaj nyob hauv cov ntawv hauv qab no: 1. Augmentin:

• Qhov ncauj ntsiav tshuaj
• Hmoov rau kev tshem tawm ntawm qhov ncauj
• Hmoov rau kev daws rau kev txhaj tshuaj.

• Hmoov rau kev ncua rau kev tswj hwm qhov ncauj.

• Cov qauv tshuaj tso tawm nrog rau kev ua yeeb yam ntev.

Nyob rau hauv lub neej txhua hnub, rau kev tsim qauv ntawm ntau yam thiab ntau hom ntawm Augmentin, feem ntau cov ntawv luv luv tau siv, suav nrog lo lus "Augmentin" thiab qhov ntsuas ntawm daim ntawv los yog cov tshuaj ntau npaum li cas, piv txwv li, raug ncua ntawm Augmentin, Augmentin 400, thiab lwm yam.

Augmentin Nqe

Tus nqi ntawm Augmentin hauv Ukraine nws txawv nyob ntawm lub tsev muag tshuaj tshwj xeeb. Nyob rau tib lub sijhawm, tus nqi ntawm cov tshuaj yog me ntsis siab dua hauv cov khw muag tshuaj hauv Kiev, ntsiav tshuaj thiab kua txiv hauv cov chaw muag tshuaj hauv Donetsk, Odessa lossis Kharkov raug muag ntawm tus nqi me ntsis.

625 mg ntsiav tshuaj (500 mg / 125 mg) tau muag hauv khw muag tshuaj, ntawm thaj tsam, ntawm 83-85 UAH. Tus nqi nruab nrab ntawm Augmentin ntsiav tshuaj 875 mg / 125 mg - 125-135 UAH.

Koj tuaj yeem yuav cov tshuaj tua kab mob hauv cov hmoov ntawv rau kev npaj cov tshuaj rau kev txhaj tshuaj nrog qhov tshuaj ntawm 500 mg / 100 mg ntawm cov tshuaj yeeb dej caw, ntawm qhov nruab nrab, rau 218-225 UAH, tus nqi nruab nrab ntawm Augmentin 1000 mg / 200 mg - 330-354 UAH.

Augmentin kev ncua kev kawm rau cov menyuam yaus: 400 mg / 57 mg (Augmentin 2) - 65 UAH, 200 mg / 28.5 mg - 59 UAH, 600 mg / 42.9 mg - 86 UAH.

Cov kev cai npaj rau ntawm kev npaj rau kev ncua ntawv

Qhov kev ncua yog npaj tam sim ua ntej siv thawj zaug.

Kwv yees li 60 ml ntawm cov dej rhaub kom txias rau chav sov yuav tsum tau ntxiv rau lub raj mis hmoov, tom qab ntawd kaw lub raj mis nrog lub hau thiab co kom txog thaum cov hmoov yaj tag, cia lub raj mis sawv ntsug li 5 feeb kom ntseeg tau tias kev ua kom tiav. Tom qab ntawd ntxiv dej rau lub cim rau ntawm lub raj mis thiab co lub raj mis dua. Hauv tag nrho, kwv yees li 92 ml ntawm dej yog xav tau los npaj qhov kev ncua.

Lub raj mis yuav tsum tau co kom zoo ua ntej txhua qhov kev siv. Txhawm rau kom raug tshuaj, qhov ntsuas yuav tsum raug siv, uas yuav tsum tau ntxuav zoo nrog dej tom qab siv txhua zaus.Tom qab kev nrawm, qhov kev ncua yuav tsum khaws cia tsis pub dhau 7 hnub hauv lub tub yees, tab sis tsis khov.

Rau cov menyuam yaus hnub nyoog qis dua 2 xyoos, kev ntsuas ib leeg ntawm kev ncua ntawm kev siv tshuaj Augmentin tuaj yeem raug txhaws ib nrab nrog dej.

Siv thaum cev xeeb tub

Augmentin tuaj yeem siv tau los ntawm cov poj niam lub sijhawm thaum coj tus menyuam hauv rooj plaub thaum cov txiaj ntsig xav tau rau leej niam outweigh qhov kev pheej hmoo rau tus menyuam hauv plab.

Augmentin tuaj yeem raug siv thaum pub mis. Nyob rau hauv kev tshwm sim uas kev noj cov tshuaj pab txhawb kev txhim kho cov kev mob tsis zoo nyob rau hauv tus menyuam, qhov teeb meem ntawm kev txwv tsis pub mis niam yuav tsum xav txog.

Kev phiv tshuaj

Augmentin tuaj yeem pab txhawb kev txhim kho ntawm cov kev xav tsis zoo no:

• Candidiasis ntawm mucous daim nyias nyias thiab tawv nqaij.
• Raws plab, xeev siab thiab ntuav.
• Mob taub hau, kiv taub hau.
• Cov tawv nqaij khaus, urticaria, tawm pob.

Nrog kev txhim kho kev ua xua, kev hloov kho Augmentin yog tso tseg tam sim ntawd.

Nws yog ib qho tsim nyog yuav tsum qhia rau tus kws kho mob txog kev txhim kho cov kev mob tshwm sim txhawm rau txhawm rau kho qhov ntau npaum li cas lossis xaiv cov kev kho mob kom zoo.

Yeeb tshuaj sib cuam tshuam

Kev siv ua ke ib txhij ntawm cov tshuaj Augmentin® thiab probenecid tsis pom zoo. Probenecid txo cov tubular ua ke ntawm amoxicillin, thiab yog li ntawd, tib lub sijhawm siv cov tshuaj Augmentin® thiab probenecide tuaj yeem ua rau nce ntxiv thiab mob siab rau hauv cov ntshav concentration ntawm amoxicillin, tab sis tsis muaj clavulanic acid.

Kev siv tib txhij ntawm allopurinol thiab amoxicillin tuaj yeem ua rau muaj kev pheej hmoo ntawm cov tawv nqaij ua xua. Tam sim no, tsis muaj cov ntaub ntawv hauv cov ntawv sau ntawm kev siv tib lub sijhawm ntawm kev sib xyaw ntawm amoxicillin nrog clavulanic acid thiab allopurinol. Penicillins tuaj yeem ua kom qeeb ntawm kev siv tshuaj methotrexate los ntawm lub cev los ntawm kev txwv tsis pub nws cov tubular tso pa, yog li kev siv Augmentin of thiab methotrexate ntau tuaj yeem ua rau kom muaj kuab lom ntawm methotrexate.

Zoo li lwm yam tshuaj tua kab mob, Augmentin® tuaj yeem cuam tshuam rau lub plab hnyuv microflora, ua rau txo qis ntawm cov tshuaj estrogen los ntawm kev mob plab thiab txo qis kev ua tau zoo ntawm kev sib xyaw ua ke ntawm lub qhov ncauj.

Cov ntawv nyeem tau piav qhia qhov tsis tshua muaj qhov tshwm sim ntawm kev nthuav dav thoob ntiaj teb kev ua piv txwv (INR) hauv cov neeg mob nrog kev siv cov acenocoumarol lossis warfarin thiab amoxicillin. Yog tias tsim nyog, kev tswj hwm tib lub sijhawm Augmentin® npaj nrog anticoagulants, lub sijhawm prothrombin lossis INR yuav tsum tau ua tib zoo saib xyuas thaum sau ntawv lossis tsum tsis npaj rau Augmentin) kev npaj) koob tshuaj tiv thaiv anticoagulants rau kev tswj hwm qhov ncauj.

Hauv cov neeg mob tau txais mycophenolate mofetil, tom qab pib siv kev sib xyaw ntawm amoxicillin nrog clavulanic acid, qhov txo qis hauv kev ua kom muaj zog ntawm cov metabolite, mycophenolic acid, tau pom ua ntej noj cov tshuaj ntxiv ntawm kwv yees li 50%. Kev hloov pauv hauv qhov kev nkag siab no tsis tuaj yeem cuam tshuam txog qhov hloov pauv ntawm kev cuam tshuam ntawm cov mycophenolic acid.

Cov lus qhia tshwj xeeb

Ua ntej pib siv cov Augmentin, keeb kwm kev kho mob ntawm tus neeg mob yuav tsum txheeb xyuas qhov tshwm sim kev tiv thaiv tus kab mob siab rau penicillin, cephalosporin thiab lwm yam.

Augmentin Kev raug ncua yuav nyob nrog tus neeg mob cov hniav. Txhawm rau kom tsis txhob muaj kev txhim kho ntawm cov txiaj ntsig zoo li no, nws txaus los ua raws txoj cai ntawm kev tu lub qhov ncauj - txhuam koj cov hniav, siv yaug dej.

Kev nkag rau Augmentin yuav ua rau kiv taub hau, yog li rau lub sijhawm ntawm kev kho mob yuav tsum tsis txhob tsav tsheb thiab ua haujlwm uas yuav tsum muaj kev mloog ntxiv.

Yuav siv tsis tau Augmentin yog tias xav tias tsam muaj mob mononucleosis uas xav tias muaj.

Augmentin muaj kev thev taus zoo thiab muaj tshuaj lom tsawg. Yog hais tias siv lub sijhawm ntev ntawm cov tshuaj yog qhov yuav tsum tau, ces nws yog qhov yuav tsum tau ua ntu zus los kuaj xyuas kev ua haujlwm ntawm lub raum thiab mob siab.

Daim ntawv tso tawm

Lub chaw tsim cov tshuaj yog lub tuam txhab British Smith Kline Beecham PLC.Augmentin muaj ntau hom, uas yog haum rau ob tus neeg laus thiab menyuam yaus. Nov yog:

• ntsiav tshuaj
• txhawb nqa cov ntsiav tshuaj
• hmoov rau kev ncua
• hmoov rau qhov kev npaj daws teeb meem rau kev ua niam txiv (kev tso ntshav lossis tso ntshav tshuaj ntawm cov tshuaj).

Feem ntau, Augmentin hauv daim ntawv ntawm cov ntsiav tshuaj yog siv rau kev kho thaum laus. Lawv tuaj yeem muaj cov kev xaiv tshuaj hauv qab no (mg amoxicillin + mg clavulanic acid):

Augmentin ntsiav tshuaj tseem muaj tus naj npawb ntawm kev zam:

• magnesium stearate,
• sodium carboxymethyl hmoov txhuv nplej siab,
• silica
• microcrystalline cellulose.

Kev ncua kev kawm kuj tseem muaj nyob hauv ntau yam tshuaj noj (400, 200 thiab 125 mg ntawm amoxicillin rau ib 5 ml).

Hmoov rau qhov kev npaj ntawm kev daws rau kev tswj hwm tshuaj muaj nyob rau hauv qhov ntau npaum ntawm 1000 thiab 500 mg ntawm amoxicillin.

Augmentin muaj nyob ntawm cov khw muag tshuaj.

Pharmacokinetics thiab cov chaw muag tshuaj

Thaum noj ntawm qhov ncauj, cov ntsiav tshuaj tau nrawm rau hauv cov ntshav los ntawm cov hnyuv. Ob peb teev tom qab siv Augmentin, qhov siab ntawm nws cov khoom hauv cov ntshav tau nce mus txog qhov siab. Lawv muab faib rau txhua daim ntaub thiab lub cev ntawm lub cev (mob ntsws, mob plab, adipose, leeg nqaij thiab pob txha, nqaij pleural thiab mob synovial, kua tsib, thiab lwm yam). Xws li cov teeb meem zoo ntawm amoxicillin muab kev kho mob rau lub ntiaj teb thiab kav ntev. Amoxicillin ua tawm los ntawm tus neeg mob lub raum, clavulanic acid tawm los ntawm lub raum thiab los ntawm kev ua cov pa ntxiv.

Augmentin raug tso cai yog tias muaj ntau qhov chaw ntawm lub cev tau kis tus kab mob:

• qis cov pa ua pa thiab lub ntsws
• cov pa ib ce ua pa
• daim tawv nqaij thiab cov nqaij mos (Staphylococcus aureus thiab qee yam lwm hom kab mob),
• cov kabmob thiab cov kabmob,
• pob txha thiab pob qij txha
• cov hniav thiab qhov ncauj kab noj hniav.

Amoxicillin pom zoo rau cov kab mob ua pa hauv qab no:

Cov kab mob ntawm lub tso zis thiab ntawm lub cev, uas cov kws kho mob feem ntau hais txog Augmentin:

Augmentin raug pom zoo hauv qee qhov teebmeem:

• mob thooj
• kho cov hniav
• sepsis (tom qab yug menyuam, tso ntshav tawm),
• septic rho menyuam.

Augmentin kuj tseem pom zoo rau kev tiv thaiv kev kis mob thaum lub sijhawm ua haujlwm thiab kev teeb tsa ntawm kev cog hniav.

Kev siv cov tshuaj thaum cev xeeb tub thiab pub niam mis

Muaj ntau tus poj niam hauv txoj hauj lwm lossis muaj menyuam yaus tau xav nyob hauv cov lus nug, nws puas tuaj yeem siv yeeb tshuaj rau hauv cov xwm txheej zoo li no? Lo lus teb meej rau tus qhab nia no tsis muaj, suav nrog hauv cov lus qhia. Tus kws kho mob uas kho tus kab mob hauv tus poj niam cev xeeb tub yuav tsum ntsuas qhov zoo thiab qhov tsis zoo, thiab tsuas yog tom qab ntawd sau ntawv rau Augmentin. Cov tshuaj ntawm cov tshuaj muaj peev xwm txeem mus rau hauv niam mis thiab los ntawm qhov chaw tso lub siab rau. Txawm li cas los xij, cov ntaub ntawv uas nws yuav ua rau tus menyuam tsis muaj. Ib qho ntxiv, cov kab mob uas nyob hauv leej niam lub cev tuaj yeem ua rau tus menyuam muaj teebmeem ntau dua li Augmentin.

Augmentin, cov lus qhia rau kev siv

Augmentin yuav tsum tau tshwj tseg raws li kws kho mob tau hais tseg, kev noj tshuaj rau nws tus kheej nrog tshuaj tua kab mob tsis tuaj yeem lees paub, tshwj xeeb yog tias tus menyuam muaj mob. Tus txheej txheem tshuaj ntawm Augmentin nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj thaum tus mob sib kis me ntsis hauv cov neeg laus yog 250 + 125 g peb zaug ib hnub. Hauv kev ua txhaum ntxiv, 500 + 125 g ntsiav tshuaj tau sau tseg peb zaug ib hnub. Lossis koj tuaj yeem noj 2 ntsiav tshuaj Augmentin 875 + 125 g ib hnub.

Nws yuav tsum tau yug los hauv lub siab tias Augmentin yuav tsum tau ua kom tiav ntawm kev txiav txim siab ncaj thiab sijhawm sib luag. Yog li, piv txwv, yog tias cov tshuaj muaj ntawv sau 3 zaug hauv ib hnub, tom qab ntawd nws yuav tsum noj txhua txhua 8 teev. Yog tias koj xav noj tshuaj 2 zaug ib hnub, tom qab ntawd koj yuav tsum ua qhov no txhua 12 teev. Cov txheej txheem zoo sib xws tso cai rau koj kom muaj cov tshuaj zoo nyob rau hauv cov ntaub so ntswg ntawm lub cev.

Cov lus qhia rau kev siv rau ncua ntawv rau cov menyuam yaus thiab cov neeg laus

Cov me nyuam Augmentin yuav tsum txhaj tshuaj kom tsawg dua. Thiab rau cov menyuam yaus, kev ncua ntawm cov tshuaj yog qhov zoo dua.Nws yuav tsum tau yug los rau hauv lub siab tias cov neeg laus tuaj yeem coj ncua kev ncua, tab sis tsuas yog ntau npaum li ntawm 400 mg rau 5 ml yog tsim rau lawv, vim tias tsuas yog nws muaj qhov zoo tshaj ntawm amoxicillin thiab clavulanic acid rau lawv. Nyob rau tib lub sijhawm, cov menyuam yaus hnub nyoog qis dua 2 xyoos tuaj yeem tsuas yog muab ncua kev kawm uas tau muab qhov koob tshuaj 125 mg. Cov menyuam yaus hnub nyoog ntau dua 2 xyoos tuaj yeem raug tso cai tsis pub ncua kev kawm ib ntus. Qhov ntau npaum li cas ntawm kev ncua hauv kev xyaum ua niam txiv yuav tsum tau muab xam raws li lub cev qhov hnyav ntawm tus menyuam thiab nws lub hnub nyoog.

Cov menyuam yaus txog li 3 hlis. nws yog ib qho tsim nyog los muab qhov tshuaj rau txhua hnub ntawm tus nqi ntawm 30 mg ntawm amoxicillin ib kg ntawm qhov hnyav. Cov menyuam yaus hnub nyoog ntau dua 3 lub hlis (txog 12 xyoos) - ntawm tus nqi ntawm 20-40 ml ib kg ntawm qhov hnyav (raug tshem tawm nrog qhov tshuaj ntawm 125 mg ntawm amoxicillin) thiab 25-45 ml ib kg ntawm qhov hnyav (raug tshem tawm 200 thiab 400 mg). Qhov yooj yim dua rau tus kab mob, qhov tshuaj tsawg dua. Nws muaj peev xwm txiav txim siab hnyav seb puas muaj kev kis mob hnyav lossis tsis, raws li lub cev kub. Yog tias nws qis dua + 38,5 ºС, tom qab ntawd tus kab mob yuav pom tias mob me, yog tias siab dua, ces nws yog mob hnyav.

Txog rau tus mob tonsillitis, mob voos, tawv nqaij thiab cov nqaij mos, nws zoo dua yog noj tshuaj amoxicillin nyob ze rau ntawm thaj chaw qis, rau lwm cov kab mob kis, ntau dua cov tshuaj noj tau ze dua ntawm ciam teb sab saud.

Cov koob tshuaj txhua hnub ntawm Augmentin kev ncua yuav tsum tau muab faib ua ntau txoj kev txhaj tshuaj thawm hnub. Cov menyuam yaus hnub nyoog qis dua 12 xyoos coj mus ncua ntawm 125 mg 3 zaug hauv ib hnub, cov seem ncua kev ncua - ob zaug ib hnub.

Cov neeg laus tuaj yeem noj 20 ml ntawm ncua kev ncua ib zaug ntawm 125 mg 2-3 zaug hauv ib hnub, lossis 11 ml ntawm ncua kev ncua ntawm 400 mg 2 zaug ib hnub. 1 ntsiav tshuaj Augmentin 875 mg yog sib npaug rau 11 ml ntawm kev ncua ntawm 400 mg. Tsis muaj lwm txoj kev xaiv rau kev hloov chaw sib npaug. Augmentin EU Ncua Kev Kawm thiab Augmentin SR cov ntsiav tshuaj tuaj yeem noj tsuas yog los ntawm cov laus thiab cov menyuam yaus uas lub cev hnyav dua 40 kg thiab tshaj 12 xyoos. Txhawm rau txhawm rau rho tawm, koj yuav tsum siv lub ntsuas ntsuas tshuaj nrog cov tshuaj. Nws tseem raug tso cai kom thim qhov kev ncua ntawv nrog cov dej ntshiab hauv qhov sib piv ntawm 1: 1.

Kev Qhia Txog Ncua Sijhawm Npaj Tseg

Rau qee tus niam txiv, nws yuav nyuaj rau thawj zaug los npaj kev ncua los ntawm cov hmoov uas twb muaj lawm, hais meej txog qhov koob xav tau. Qhov tseeb, qhov no tsis yog qhov nyuaj. Ua ntej tshaj plaws, nws yog qhov yuav tsum tau coj mus rau hauv tus account tias rau qhov kev npaj ntawm kev ncua, txhua cov hmoov los ntawm lub raj mis yuav tsum siv tam sim ntawd, tso nws rau tom qab yog tsis pom zoo.

Txhawm rau npaj qhov kev ncua, ntxiv 60 ml dej rhaub ntawm chav sov mus rau lub raj mis hmoov, tom qab ntawd kaw lub raj mis nrog lub hau thiab muab nws ua kom khov kho kom txog thaum cov hmoov yaj tag. Tom qab ntawd nws yog ib qho tsim nyog yuav tau muab lub raj mis tso ncaj rau 5 feeb. Yog tias tsis muaj kev ziab hauv qab, tom qab ntawd mam li nchuav dej rau hauv lub thauv rau lub cim. Kev tshem tawm tiav tuaj yeem khaws cia rau hauv tub yees, tab sis tsis pub dhau ib lub lim tiam.

Cov lus qhia rau kev npaj cov tshuaj rau kev kho mob siab

Nws yog ib qho tsim nyog yuav tau ceev cov ntsiab lus ntawm cov hmoov vial hauv dej. Tus nqi dej uas yuav tsum tau rau txoj haujlwm no yog nyob ntawm seb ntau npaum cas. Yog tias qhov ntau npaum li cas yog 500/100, tom qab ntawd 10 ml dej yuav tsum tau noj, yog tias 1000/200, tom qab ntawd 20 ml. Ib nrab ntawm cov ntim no yog ntxiv rau lub raj mis hmoov, tom qab ntawd nws yog shaken kom txog thaum cov hmoov yaj tag. Tom qab ntawd lub raj mis settles rau 5 feeb. Yog tias tsis muaj kev ziab hauv qab, tom qab ntawd cov dej ntxiv yog ntxiv rau lub raj mis. Kev daws tuaj yeem xav npaj txhij rau kev siv tsuas yog thaum tsis muaj sediment uas tseem nyob hauv qab ntawm lub vial. Txoj kev daws teeb meem yuav tsum tau npaj tam sim ua ntej siv, cov tshuaj tiav tiav tuaj yeem khaws cia rau tsis pub dhau 20 feeb.

Thaum infused, cov tshuaj tiav tau muab ntxiv rau kua dej rau infusion (piv txwv li, saline), npaj rau kev siv hauv cov kua. Txhawm rau 500/100 cov tshuaj tua kab mob, 50 ml ntawm dej qab ntsev yog qhov tsim nyog, rau cov tshuaj 1000/200 tshuaj tua kab mob, 100 ml cov kua ntsev. Qhov kev daws teeb meem rau Txoj kev lis ntshav tuaj yeem khaws cia rau 3-4 teev.

Lub sijhawm ntawm dav hlau txhaj ntawm qhov tau txais ntawm qhov daws tau yog 3-4 feeb, lub sijhawm infusion yog 30-40 feeb.

Lwm cov lus qhia

Rau cov neeg muaj teeb meem lub raum, cov koob tshuaj yuav tsum tau kho qis dua. Nrog creatinine qhov kev tshem tawm ntau tshaj 30 ml / min, tsis tas yuav hloov kho tshuaj. Nrog rau kev tshem tawm ntawm 10-30 ml / min, thaum xub thawj 1 koob ntawm 1000 mg / 200 mg yog cov tshuaj, tom qab ntawd - 500 mg / 100 mg 2 zaug / hnub.Nrog rau kev tshem tawm tsawg dua 10 ml / min - thaum xub thawj 1 koob ntawm 1000 mg / 200 mg yog cov tshuaj kho, tom qab ntawd - 500 mg / 100 mg txhua 24 teev. Cov neeg laus hauv plab tsis tas yuav txo qhov tshuaj kom tsawg.

Thaum kho Augmentin ntev, nws raug pom zoo kom saib xyuas lub luag haujlwm hauv lub siab, lub raum thiab ntshav ntxiv.

Lub sijhawm tiv thaiv cov tshuaj tua kab mob yog txiav txim siab raws qhov mob hnyav ntawm tus kabmob. Feem ntau, tus kws kho mob sau ib txog kev kho mob hauv 7 hnub. Ib chav kawm ntawm kev siv tshuaj tua kab mob tsawg dua 5 hnub tsis paub. Ntawm qhov tod tes, nws tseem tsis pom zoo kom siv cov tshuaj no ntev, ntev dua 14 hnub. Tom qab lub sijhawm no, tus kws kho mob yuav tsum ntsuas lub chaw kuaj mob. Yog tias cov tsos mob ntawm tus kabmob tsis ploj mus tom qab ib lub hlis thiab ib nrab, tom qab ntawd nws yuav tsum hloov txoj kev kho mob lossis hloov cov tshuaj nrog ib qho zoo dua. Txawm li cas los xij, hauv qee kis Augmentin kev kho mob yog ua tau rau 3-4 lub lim tiam. Lwm cov kev kawm ntawm kev txhaj tshuaj ntawm cov tshuaj thiab coj nws hauv cov qauv tshuaj kuj ua tau.

Nws puas tuaj yeem faib cov ntsiav tshuaj ntawm cov tshuaj rau hauv qhov chaw? Qhov no tsis pom zoo. Raws li cov lus qhia rau kev siv, cov tshuaj hauv cov ntsiav tshuaj yuav tsum nqos tag nrho, tsis tas yuav zom thiab haus dej ntau.

Nws yog qhov zoo tshaj rau noj Augmentin thaum pib noj mov. Txawm li cas los xij, qhov no tsis yog qhov kev pom zoo nruj, txij li qhov nqus ntawm cov tshuaj tsis cuam tshuam rau cov khoom noj. Txawm li cas los xij, kev tshawb fawb pom tau tias thaum noj cov tshuaj nrog zaub mov, qhov ntxim nyiam ntawm kev phiv yog tsawg heev.

Dosage daim ntawv

Hmoov rau kev tshem tawm qhov ncauj 200 mg / 28.5 mg / 5 ml, 70 ml

5 ml ntawm kev tshem tawm muaj

yam tshuaj: amoxicillin (li amoxicillin trihydrate) 200 mg,

clavulanic acid (raws li poov tshuaj clavulanate) 28.50 mg,

tus zam: xanthan ntawm cov pos hniav, aspartame, succinic acid, anhydrous colloidal silicon dioxide, hypromellose, txiv kab ntxwv qhuav tsw 610271 E, txiv kab ntxwv qhuav tsw 9/027108, txiv pos huab tsw NN07943, suab thaj tsw tsw tsw 52927 / AR, anhydrous silicon dioxide.

Lub hmoov yog xim dawb lossis yuav luag dawb nrog lub ntsej muag tsw. Qhov npaj ncua cia yog xim dawb lossis yuav luag dawb, thaum sawv ntsug, dej nag lossis daus dawb yuav luag maj mam tsim.

Analogues ntawm cov tshuaj

Augmentin tsis deb ntawm cov tshuaj nkaus xwb rau hauv kev ua lag luam uas muaj clavulanic acid thiab amoxicillin hauv nws cov lus. Ntawm cov tshuaj feem ntau, cov npe ua:

Ntau ntawm lawv muaj tus nqi pheej yig dua piv rau Augmentin. Txawm li cas los xij, cov neeg mob uas yog cov neeg mob uas tsis xav ua kom muaj kev pheej hmoo thiab uas xav daws qhov tshuaj nrog kev lees paub zoo yog qhov zoo tshaj plaws siv Augmentin.

Cov chaw muag tshuaj

Farmakokinetics

Amoxicillin thiab clavulanate yaj tau zoo nyob rau hauv cov kev daws teeb meem nrog lub cev pH, sai thiab tag nrho los ntawm lub plab zom mov tom qab kev tswj hwm qhov ncauj. Kev nqus ntawm amoxicillin thiab clavulanic acid yog qhov zoo dua thaum noj cov tshuaj thaum pib noj mov. Tom qab noj cov tshuaj hauv, nws txoj kev noj qab haus huv yog 70%. Cov xaib ntawm ob qho tshuaj ntawm cov tshuaj no zoo sib xws thiab mus txog qhov siab tshaj plaws ntshav plasma concentration (Tmax) hauv thaj tsam li 1 teev. Qhov kev sib xyaw ntawm amoxicillin thiab clavulanic acid hauv cov ntshav cov ntshav yog tib yam ob qho tib si kev sib xyaw ua ke ntawm kev siv amoxicillin thiab clavulanic acid, thiab txhua feem sib xyaw.

Kev kho mob ntau ntawm amoxicillin thiab clavulanic acid yog ua tiav hauv ntau yam plab hnyuv siab raum thiab cov ntaub so ntswg, cov kua dej interstitial (mob ntsws, plab hnyuv plab, lub zais zis, adipose, pob txha thiab cov leeg nqaij, pleural, synovial thiab peritoneal kua, tawv nqaij, bile, purulent paug, hnoos qeev). Kev siv Amoxicillin thiab clavulanic acid tsis nkag mus rau hauv cov kua dej ua kua hlwb.

Kev khi ntawm amoxicillin thiab clavulanic acid rau ntshav cov ntshav yog muaj ntsis: 25% rau clavulanic acid thiab 18% rau amoxicillin. Amoxicillin, zoo li feem ntau rau penicillins, raug tawm hauv niam cov kua mis. Ib co kua nplaum ntawm clavulanic acid kuj tau pom nyob rau hauv niam cov kua mis.Txhawm rau kev zam ntawm kev pheej hmoo ntawm kev hnov ​​mob, amoxicillin thiab clavulanic acid tsis cuam tshuam loj rau kev noj qab haus huv ntawm cov menyuam mos uas pub niam mis. Amoxicillin thiab clavulanic acid hla qhov chaw tiv thaiv hniav.

Amoxicillin tsuas yog tawm hauv lub raum, thaum clavulanic acid tawm los ntawm ob lub raum thiab ntxiv cov tshuab. Tom qab cov tshuaj noj ib qhov ncauj ntawm ib ntsiav tshuaj ntawm 250 mg / 125 mg los sis 500 mg / 125 mg, kwv yees li 60-70% ntawm amoxicillin thiab 40-65% ntawm clavulanic acid raug tshem tawm tsis hloov pauv hauv cov zis thaum thawj 6 teev.

Amoxicillin yog qee cov tso tawm hauv cov zis hauv daim ntawv ntawm tsis muaj zog penicillinic acid nyob rau hauv ib qho nyiaj npaum li 10-25% ntawm cov koob tshuaj. Clavulanic acid nyob rau hauv lub cev tau dav rau 2,5-dihydro-4- (2-hydroxyethyl) -5-oxo-1H-pyrrole-3-carboxylic acid thiab 1-amino-4-hydroxy-butan-2-ib thiab yog tawm nrog tso zis thiab quav, ntxiv rau hauv cov qauv ntawm cov pa roj carbon dioxide los ntawm kev ua pa tawm.

Cov Tshuaj Hauv Tshuaj

Augmentin® yog cov tshuaj tua kab mob sib xyaw ua ke uas muaj amoxicillin thiab clavulanic acid, nrog rau kev pom dav ntawm cov kab mob hauv lub cev, tiv taus beta-lactamase.

Amoxicillin yog cov tshuaj tua kab mob ntau tshaj ib nrab hnub uas dhia tawm tsam ntau yam kab mob gram-positive thiab gram-tsis zoo. Amoxicillin raug pov tseg los ntawm beta-lactamase thiab tsis cuam tshuam rau cov kab mob me me uas tsim cov enzyme no. Cov txheej txheem ntawm kev ua ntawm amoxicillin yog rau kev txwv tsis pub lub biosynthesis ntawm peptidoglycans ntawm cov kab mob ntawm phab ntsa, uas feem ntau ua rau lysis thiab cell tuag.

Clavulanic acid yog beta-lactamate, zoo ib yam li hauv cov qauv hauv tshuaj lom rau penicillins, uas muaj peev xwm inactivate beta-lactamase enzymes ntawm cov kab mob me uas tawm tsam penicillins thiab cephalosporins, yog li tiv thaiv qhov ua tsis tiav ntawm amoxicillin. Beta-lactamases yog ua los ntawm ntau cov kab mob gram-positive thiab gram-tsis zoo. Kev ua ntawm beta-lactamases tuaj yeem ua rau muaj kev puas tsuaj rau qee yam tshuaj tua kabmob txawm tias ua ntej lawv pib cuam tshuam cov pathogens. Clavulanic acid thaiv qhov kev txiav txim ntawm cov enzymes, rov kho qhov rhiab ntawm cov kab mob mus rau amoxicillin. Hauv tshwj xeeb, nws muaj cov haujlwm siab tiv thaiv plasmid beta-lactamases, uas cov tshuaj tiv thaiv feem ntau cuam tshuam, tab sis tsis muaj txiaj ntsig tawm tsam hom 1 chromosome beta-lactamases.

Muaj cov clavulanic acid nyob rau hauv Augmentin® tiv thaiv amoxicillin los ntawm kev puas tsuaj ntawm beta-lactamases thiab nthuav nws lub zog ntawm kev ua haujlwm tiv thaiv kab mob nrog rau kev suav nrog cov kab mob me me uas feem ntau tiv taus lwm yam penicillins thiab cephalosporins. Clavulanic acid nyob rau hauv daim ntawv ntawm ib qho tshuaj tsis muaj qhov ua kom muaj kev tiv thaiv kab mob tseem ceeb.

Txhim kho txoj kev tawm tsam

Nws muaj 2 lub txheej txheem rau kev txhim kho ntawm kev tiv thaiv rau Augmentin®

- kev tsis ua haujlwm los ntawm cov kab mob beta-lactamases, uas tsis raug rau qhov cuam tshuam ntawm clavulanic acid, suav nrog cov chav kawm B, C, D

- deformation ntawm penicillin-khi protein, uas ua rau kom txo qis ntawm qhov xwm txheej ntawm cov tshuaj tua kab mob cuam tshuam nrog cov kab mob me

Lub zog tsis zoo ntawm cov kab mob phab ntsa, nrog rau cov txheej txheem ntawm lub twj tso kua mis, tuaj yeem ua rau los yog pab txhawb kev txhim kho ntawm kev tawm tsam, tshwj xeeb tshaj yog cov kab mob gram-tsis zoo.

Augmentin®muaj cov nyhuv bactericidal ntawm cov kab mob hauv qab no:

Gram-zoo aerobes: Enterococcus faecalis,Gardnerella vaginalis,Dab Tsi Staphylococcus aureus (rhiab rau methicillin), coagulase-negative staphylococci (rhiab rau methicillin), Tus kab mob Streptococcus agalactiae,Kab mob ntsws dej liab1,Cov kab mob Streptococcus pyogenes thiab lwm yam beta hemolytic streptococci, pab pawg Streptococcus viridans,Bacillius anthracis, Listeria monocytogenes, Nocardia cov hnub qub

Gram-negative aerobes: Actinobacillusactinomycetemcomitans,Capnocytophagaspp.,Eikenellacorrodens,Haemophilusmob khaub thuas,Moraxellacatarrhalis,Neisseriagonorrhoeae,Pasteurellamultocida

anaerobic microorganisms: Bacteroides fragilis,Fusobacterium nucleatum,Prevotella spp.

Cov kab mob uas muaj qhov ua tau kom tiv taus

Gram-zoo aerobes: Enterococcusfaecium*

Cov kab mob nrog lub ntuj tsis kam:

gram-negative aerobes: Acinetobacterhom,Citrobacterfreundii,Enterobacterhom,Legionella pneumophila, Morganella morganii, Providenciahom, Pseudomonashom, Serratiahom, Stenotrophomonas maltophilia,

lwm yam: Chlamydia trachomatis,Chlamydophila mob ntsws, Chlamydophila psittaci, Coxiella burnetti, Mycoplasma pneumoniae.

*Lub cev rhiab heev nyob rau hauv qhov tsis muaj kis tau ua hauj

1 Tsis suav hom Kab mob ntsws dej liabpenicillin tiv taus

Tsuas tshuaj thiab tswj hwm

Lub txim rau kev tswj hwm ntawm qhov ncauj yog npaj rau siv hauv kev kho mob hauv hlwb.

Qhov rhiab siab rau Augmentin® yuav txawv raws qhov chaw thiab lub sijhawm. Ua ntej sau tshuaj, yog tias ua tau nws yuav tsum tau los ntsuas qhov rhiab ntawm cov kab mob raws li cov ntaub ntawv hauv zos thiab txiav txim siab qhov rhiab siab los ntawm kev kuaj thiab ntsuas cov qauv los ntawm tus neeg mob tshwj xeeb, tshwj xeeb yog kis mob hnyav.

Cov tshuaj muab rau noj yog teem raws li lub hnub nyoog, lub cev nyhav, lub raum kev ua haujlwm, kev kis tus kab mob, nrog rau qhov mob hnyav heev.

Augmentin® pom zoo kom noj thaum pib noj mov. Lub sijhawm kho yog nyob ntawm tus neeg mob cov lus teb rau kev kho mob. Qee cov kab mob pathologies (tshwj xeeb, osteomyelitis) yuav xav tau kev kawm ntev dua. Txoj kev kho yuav tsum tsis txhob txuas ntxiv rau 14 hnub yam tsis rov ntsuas nws tus mob. Yog tias tsim nyog, nws yog qhov ua tau los ua cov kauj ruam kev kho mob (thawj zaug, kev tswj hwm cov tshuaj nrog kev hloov pauv tom qab kev tswj hwm hauv qhov ncauj).

Cov menyuam yaus txij li 2 hlis txog 12 xyoos lossis hnyav dua 40 kg

Qhov koob tshuaj, nyob ntawm lub hnub nyoog thiab qhov hnyav, tau qhia hauv mg / kg lub cev qhov hnyav hauv ib hnub lossis hauv milliliters ntawm cov kev ncua kev ua tiav.

Cov tshuaj pom zoo:

- txij li 25 mg / 3.6 mg / kg / hnub mus txog 45 mg / 6.4 mg / kg / hnub, muab faib ua 2 koob tshuaj, txhawm rau kis mob me thiab mob nyhav (mob tons, ua mob rau daim tawv thiab cov nqaij mos mos)

- txij li 45 mg / 6.4 mg / kg / hnub txog 70 mg / 10 mg / kg / hnub, muab faib ua 2 koob tshuaj, txhawm rau kho kab mob loj dua (mob otitis media, sinusitis, mob ntsws qis dua).

Augmentin Ib Leeg Daim Ntawv Xaiv Xaiv® nyob ntawm lub cev hnyav.