Yuav Noj Diagninid li cas rau ntshav qab zib?

Muaj ib ntsiav tshuaj:

Repaglinide nyob rau hauv cov nqe lus ntawm 100% tshuaj - 0.5 mg, 1 mg thiab 2 mg,

Poloxamer (hom 188) 3 mg, 3 mg lossis 3 mg, meglumine 10 mg, 10 mg lossis 13 mg, lactose monohydrate 47.8 mg, 47.55 mg lossis 61.7 mg, microcrystalline cellulose 33.7 mg, 33, 45 mg lossis 45 mg, potassium polacryline 4 mg, 4 mg lossis 4 mg, colloidal silicon dioxide 0.5 mg, 0.5 mg lossis 0.7 mg, magnesium stearate 0.5 mg, 0.5 mg lossis 0.6 mg feem.

Cov Tshuaj Hauv Tshuaj

Cov tshuaj tiv thaiv luv luv qhov ncauj hypoglycemic tshuaj. Tsim kho kev tsim cov tshuaj insulin los ntawm kev ua haujlwm ntawm cov hlwb ua haujlwm ntawm cov txiav. Nws nplov ATP-nyob rau hauv cov hlab ntsha hauv beta cov kab mob los ntawm cov phiaj protein, uas ua rau txoj kev depolarization ntawm beta hlwb thiab qhib cov calcium calcium. Ib qho nce ntawm cov calcium ions tsim cov tshuaj insulin zais cia. Hauv cov neeg mob uas muaj hom 2 mob ntshav qab zib mellitus, qhov tshuaj insulinotropic rau kev noj zaub mov raug pom muaj nyob hauv 30 feeb tom qab kev noj cov tshuaj. Qhov no muab qhov txo qis hauv cov concentration ntawm cov piam thaj hauv cov ntshav thaum lub sijhawm tag nrho ntawm kev noj zaub mov. Hauv qhov no, qhov concentration ntawm repaglinide hauv lub plasma sai dua, thiab 4 teev tom qab noj tshuaj, qhov tsis tshua muaj siab ntawm repaglinide raug tshawb pom nyob hauv cov ntshav ntawm cov neeg mob ntshav qab zib hom 2. Thaum siv cov tshuaj repaglinide hauv thaj tsam li ntawm 0.5 txog 4 mg, qhov ceeb toom koob tshuaj txo qis hauv cov piam thaj hauv qab tau sau tseg.

Cov Tshuaj Pharmacokinetics

Thaum noj ntawm qhov ncauj, qhov nqus ntawm repaglinide los ntawm lub plab zom mov yog qhov siab. Lub sijhawm kom mus txog qhov siab tshaj yog 1 teev. Qhov nruab nrab ntawm kev nruab nrab ntawm kev rov ua dua tshiab yog 63% (kev hloov pauv qhov sib piv yog 11%). Txij li thaum titration ntawm ib koob tshuaj repaglinide yog nqa tawm nyob ntawm cov lus teb rau kev kho, kev hloov pauv tsis cuam tshuam rau kev ua hauj lwm zoo ntawm kev kho.

Kev faib khoom ntim - 30 l. Kev sib txuas lus nrog cov ntshav plasma protein - 98%.

Nws yog tag nrho metabolized hauv lub siab los ntawm kev cuam tshuam rau CYP3A4 rau cov kev hloov pauv tsis muaj zog.

Nws yog tawm hauv feem ntau los ntawm txoj hnyuv, los ntawm lub raum - 8% nyob rau hauv daim ntawv ntawm metabolites, los ntawm txoj hnyuv - 1%. Ib nrab-lub neej yog 1 teev.

Kev siv cov tshuaj repaglinide hauv kev siv li niaj zaus hauv cov neeg mob uas lub siab tsis ua haujlwm tuaj yeem ua rau muaj qhov siab dua ntawm repaglinide thiab nws cov metabolites dua li ntawm cov neeg mob uas lub siab ua haujlwm. Hauv qhov no, kev siv cov tshuaj repaglinide yog contraindicated rau hauv cov neeg mob uas muaj mob hepatic tsis zoo, thiab hauv cov neeg mob uas tsis muaj peev xwm ua rau hepatic muaj mob me me mus rau daim siab repaglinide yuav tsum siv nrog ceev faj. Lub sijhawm nruab nrab ntawm kev kho kom haum rau koob tshuaj yuav tsum tau nce ntxiv kom muaj kev txheeb xyuas tau zoo dua cov lus teb rau kev kho.

Thaj chaw hauv qab txoj kab nruab nrab-concentration (AUC) thiab qhov siab tshaj plaws ntawm repaglinide hauv ntshav (Cmax) zoo ib yam rau cov neeg mob lub raum tsis ua haujlwm thiab hauv cov neeg mob uas lub raum tsis ua haujlwm ntawm qhov mob me lossis mob hnyav. Hauv cov neeg mob uas mob raum tsis zoo, tau nce ntxiv hauv AUC thiab C raug sau tsegmaxtxawm li cas los xij, tsuas muaj kev cuam tshuam tsis muaj qhov tsis zoo ntawm kev saib xyuas ntawm repaglinide thiab creatinine qhov kev qhia tawm tau qhia tawm. Nws zoo nkaus li tias cov neeg mob uas lub raum tsis ua haujlwm tsis muaj qhov yuav tsum tau hloov kho thawj zaug. Txawm li cas los xij, ib qho kev nce ntxiv ntawm cov neeg mob uas muaj hom 2 mob ntshav qab zib mellitus txuam nrog kev mob tsis zoo hauv lub raum, uas yuav tsum tau hemodialysis, yuav tsum ua nrog ceev faj.

Kev Tshuaj Ntsuam Xyuas: Kev Qhia Tawm

Hom 2 mob ntshav qab zib mellitus (nrog rau kev noj haus tsis zoo, kev hnyav thiab kev siv lub cev) hauv monotherapy lossis kev sib xyaw nrog metformin lossis thiazolidinediones hauv qhov xwm txheej tsis tuaj yeem ua kom tiav txaus siab glycemic tswj nrog monotherapy nrog repaglinide lossis metformin lossis thiazolidinediones.

Kev Ntsuas: Tshuaj Tiv Thaiv Tsis Txaus

- Paub txog kev ua haujlwm hypersensitivity rau repaglinide lossis rau ib qho ntawm cov tshuaj ntawm cov tshuaj,

- Hom 1 ntshav qab zib

- Tus kab mob ntshav qab zib ketoacidosis, mob ntshav qab zib precoma thiab coma,

- Cov kab mob kis tau, kev phais mob loj thiab lwm yam mob uas yuav tsum tau kho cov tshuaj insulin,

- Kev tsis mob siab rau lub siab ua haujlwm,

- Kev teem caij sib txig ntawm gemfibrozil (saib "Kev cuam tshuam nrog lwm cov tshuaj"),

- Lactase deficiency, lactose intolerance, qabzib-galactose malabsorption,

- Cev xeeb tub thiab lactation,

- Cov menyuam yaus hnub nyoog txog 18 xyoo.

Cov kev tshawb fawb soj ntsuam hauv cov neeg mob hnub nyoog qis dua 18 xyoo thiab laus dua 75 xyoo tseem tsis tau ua.

Nrog saib xyuas (qhov yuav tsum tau ua tib zoo saib xyuas) yuav tsum tau siv rau lub siab ua haujlwm tsis txaus ntawm qhov kev ua haujlwm qib me, febrile syndrome, mob raum tsis ua haujlwm, kev quav dej cawv, muaj mob loj, kev noj haus tsis zoo.

Cev xeeb tub thiab lactation

Cov kev tshawb fawb txog kev siv cov tshuaj repaglinide rau cov poj niam cev xeeb tub tsis tau ua. Yog li ntawd, kev nyab xeeb ntawm repaglinide hauv cov poj niam cev xeeb tub tsis tau kawm txog.

Lub sijhawm pub mis niam

Cov kev tshawb fawb txog kev siv cov tshuaj repaglinide rau cov poj niam thaum lub sijhawm pub mis niam tseem tsis tau ua. Yog tias nws yuav tsum tau siv cov tshuaj thaum lub sijhawm pub niam mis, pub mis rau menyuam noj yuav tsum tsis pub mus ntxiv.

Tsuas tshuaj thiab tswj hwm

Cov tshuaj Diagnlinid ® yog tshuaj tawm rau cov tshuaj noj rau lub cev thiab kev ua kom lub cev kom txo qis cov ntshav qabzib hauv cov ntshav, nws txoj kev tswj hwm yuav tsum ua kom raug sijhawm rau kev noj mov.

Cov tshuaj tau noj ntawm qhov ncauj ua ntej noj mov loj 2, 3 lossis 4 zaug hauv ib hnub, feem ntau 15 feeb ua ntej noj mov, tab sis kuj tseem tuaj yeem ua li ntawm 30 feeb ua ntej noj mov kom txog lub sijhawm tam sim ntawd noj.

Cov koob tshuaj ntawm cov tshuaj tau xaiv ib tus zuj zus rau txhua tus neeg mob, nyob ntawm kev mloog ntawm cov piam thaj hauv cov ntshav.

Thawj koob tshuaj yog 0.5 mg / hnub (yog tias tus neeg mob noj lwm qhov tshuaj hypoglycemic qhov ncauj - 1 mg). Kev hloov kho koob tshuaj yog ua 1 zaug hauv ib lub lis piam lossis 1 zaug hauv 2 lub lis piam (thaum tsom mus rau kev mloog zoo ntawm cov piam thaj hauv cov ntshav, ua piv txwv ntawm kev teb rau kev kho). Qhov siab tshaj plaws ib koob yog 4 mg. Qhov siab tshaj plaws niaj hnub noj yog 16 mg.

Hloov chaw ntawm cov neeg mob uas kho nrog lwm cov tshuaj hypoglycemic hauv qhov ncauj Repaglinide kho mob tuaj yeem ua tiav tam sim ntawd. Txawm li cas los xij, kev sib raug zoo ntawm kev txhaj tshuaj ntawm repaglinide thiab cov koob tshuaj ntawm lwm cov tshuaj hypoglycemic tseem tsis tau qhia tawm. Qhov pom zoo tshaj plaws thawj zaug koob tshuaj repaglinide thaum pauv ntawm lwm cov tshuaj hypoglycemic yog 1 mg ua ntej noj mov tseem ceeb.

Repaglinide tuaj yeem kho nrog kev sib xyaw nrog metformin lossis thiazolidinediones thaum tsis muaj ntshav qabzib tsis txaus tswj kev kho mob monotherapy nrog metformin, thiazolidinediones lossis repaglinide. Hauv qhov xwm txheej no, tib qho kev pib siv ntawm repaglinide yog siv ib yam li nrog kev kho mob monotherapy. Tom qab ntawv nqa tawm cov tshuaj txhaj rau txhua qhov tshuaj nyob ntawm qhov ua tiav ntawm cov piam thaj hauv cov ntshav.

Cov pab pawg neeg tshwj xeeb

(saib tshooj "Cov Lus Qhia Tshwj Xeeb").

Nws tsis pom zoo kom siv cov tshuaj repaglinide rau cov neeg tsis tau muaj 18 xyoo vim tias tsis muaj ntaub ntawv txaus rau nws txoj kev nyab xeeb thiab kev ua haujlwm hauv pawg neeg mob no.

Kev Tshuaj Ntsuam Xyuas: Sab Sijhawm

Cov kev mob tshwm sim feem ntau yog hypoglycemia, qhov ntau zaus uas yog, raws li nrog txhua hom mob ntshav qab zib mellitus txoj kev kho, ntawm tus kheej rau qee yam xws li kev noj zaub mov, noj tshuaj, ua si lub cev thiab kev ntxhov siab.

Cov hauv qab no yog cov kev phiv pom nrog kev siv cov tshuaj repaglinide thiab lwm qhov kev tiv thaiv kab mob hauv lub qhov ncauj. Txhua qhov kev mob tshwm sim yog pawg raws qhov qhov nquag ntawm txoj kev loj hlob, txhais tias: feem ntau (≥1 / 100 txog

Nrog rau kev siv tshuaj ntau dhau, ua rau lub ntsej muag ntshav qab zib yuav pib ua.

Cov tsos mob kev tshaib kev nqhis, tawm hws, tshee tshee, tshee tshee, ntxhov siab, mob taub hau, pw tsaug zog, txob taus, nyuaj siab, tsis hais lus thiab tsis pom kev.

Thaum siv cov tshuaj repaglinide rau cov neeg mob uas muaj hom 2 mob ntshav qab zib mellitus hauv ib lis piam nce ntawm 4 mus rau 20 mg 4 zaug hauv ib hnub (nrog rau txhua pluas noj), ib tus txheeb ze tshaj plaws tau pom rau 6 lub lis piam, ua kom pom los ntawm kev txo cov ntshav qabzib ntau dua nrog kev txhim kho cov tsos mob ntawm tus mob qog ntshav qab zib.

Thaum muaj cov tsos mob ntawm lub qog ntshav qab zib, yuav tsum ua cov kev ntsuas tsim nyog los ua kom cov ntshav qabzib ntau hauv cov ntshav (noj dextrose lossis zaub mov ntau hauv carbohydrates hauv). Hauv kev mob ntshav qis (tsis nco qab, tsis nco qab lawm), dextrose yog muab tshuaj rau leeg. Tom qab rov qab ntawm kev nco qab - qhov kev nkag los ntawm cov khoom noj khoom haus tau yooj yim (kom tsis txhob rov qab txhim kho hypoglycemia).

Kev sib txuam

Qhov ua tau muaj kev cuam tshuam ntawm repaglinide nrog cov tshuaj uas cuam tshuam rau cov metabolism hauv cov piam thaj yuav tsum raug suav nrog.

Kev tiv thaiv kab mob, thiab yog li tshem tawm cov tshuaj repaglinide, tuaj yeem hloov pauv nyob rau hauv cov tshuaj uas cuam tshuam, txhawb lossis ua kom cov ntshav enzymes los ntawm pawg cytochrome P-450. Yuav tsum tau ceev faj tshwj xeeb nrog kev tswj hwm tib lub sijhawm ntawm CYP2C8 thiab CYP3A4 inhibitors nrog repaglinide. Cov kev tshawb fawb pom tau tias kev tswj hwm tib txhij ntawm Deferasirox, uas yog qhov ua kom tsis muaj zog ntawm CYP2C8 thiab CYP3A4, thiab repaglinide ua rau muaj qhov nce ntawm cov txheej txheem ib puag ncig ntawm repaglinide, nrog me ntsis tab sis tseem ceeb txo cov ntshav qabzib hauv siab. Nrog rau kev tswj hwm tib txhij ntawm Deferasirox thiab Repaglinide, nws yog ib qho tsim nyog yuav tau xav txog qhov txo qis ntawm koob tshuaj Repaglinide thiab ua tib zoo saib xyuas cov concentration ntawm cov piam thaj hauv cov ntshav.

Nrog rau kev siv clopidogrel, ib qho CYP2C8 inhibitor, thiab repaglinide, qhov nce ntawm cov kab mob rau cov tshuaj repaglinide thiab txo qis me ntsis hauv cov ntshav qabzib hauv lub siab tau pom. Yog tias cov tshuaj repaglinide thiab clopidogrel siv ua ke, kev saib xyuas zoo ntawm cov piam thaj thiab kev soj ntsuam hauv chav kho mob yuav tsum tau nqa tawm.

OATP1B1 anion thauj protein inhibitors (xws li, cyclosporin) kuj tseem tuaj yeem nce plasma repaglinide ntau ntau.

Cov tshuaj hauv qab no tuaj yeem txhim kho thiab / lossis ntev li qhov cuam tshuam hypoglycemic ntawm repaglinide:

Gemfibrozil, trimethoprim, rifampicin, clarithromycin, ketoconazole, itraconazole, cyclosporine, lwm yam tshuaj hypoglycemic, monoamine oxidase inhibitors, tsis xaiv-beta-adrenergic thaiv cov kab mob, angiotensin hloov enzyme inhibitors, salicylate, nonsteroidalide.

Beta-blockers tuaj yeem npog cov tsos mob ntawm kev mob ntshav qab zib.

Kev tswj hwm tib lub sij hawm ntawm cimetidine, nifedipine lossis simvastatin (uas yog cov kab mob sib txuas ntawm CYP3A4) nrog repaglinide tsis cuam tshuam loj heev rau pharmacokinetic cov kev txwv ntawm repaglinide.

Repaglinide tsis ua rau kev mob loj ua rau muaj kev noj tshuaj ntawm digoxin, theophylline, lossis warfarin thaum siv rau hauv cov neeg ua haujlwm zoo. Yog li, tsis tas yuav tsum tau txhaj koob tshuaj ntawm cov tshuaj no thaum muab sib xyaw nrog repaglinide.

Cov tshuaj hauv qab no tuaj yeem ua kom cov nyhuv hypoglycemic ntawm repaglinide:

Cov tshuaj tiv thaiv hauv qhov ncauj, rifampicin, barbiturates, carbamazepine, thiazides, glucocorticosteroids, danazole, cov thyroid hormones thiab sympathomimetics.

Daim ntawv thov sib koom ua ke qhov ncauj tiv thaiv kev sib deev (ethinyl estradiol / levonorgestrel) tsis ua rau thaj chaw kho mob muaj kev hloov pauv nyob rau hauv tag nrho kev nyab xeeb ntawm kev rov kho dua tshiab, txawm hais tias qhov siab tshaj plaws ntawm repaglinide tau tiav ua ntej lawm. Repaglinide tsis ua rau thaj chaw muaj kev cuam tshuam zoo txog kev noj qab haus huv ntawm levonorgestrel, tab sis nws cov txiaj ntsig ntawm kev siv hluav taws xob bioavailability ntawm ethinyl estradiol tsis tuaj yeem txiav txim siab.

Hauv qhov no, thaum lub sijhawm teem lossis tshem tawm cov tshuaj saum toj saud, cov neeg mob uas twb tau txais repaglinide yuav tsum tau saib xyuas kom nruj kom ncav sijhawm txhawm rau ua txhaum kev tswj hwm glycemic.

Cov lus qhia tshwj xeeb

Repaglinide yog qhia txog kev tswj tsis zoo glycemic thiab kev mob siab rau mob ntshav qab zib mellitus thaum kho kev noj zaub mov zoo, tawm dag zog, thiab lub cev poob.

Txij li thaum cov tshuaj repaglinide yog cov tshuaj uas ua rau cov kua dej hauv lub siab tsis txaus, nws yuav ua rau lub cev tsis muaj ntshav qab zib. Nrog rau kev sib txuas ua ke, kev pheej hmoo ntawm Kev txo ntshav siab poob nce.

Kev phais mob thiab kev raug mob loj, kev kub nyhiab, kev kis kab mob nrog febrile syndrome yuav tsum tsis siv tshuaj ntxiv hauv qhov ncauj thiab tshuaj kho mob ib ntus.

Nws yog ib qho tsim nyog yuav tsum tau soj ntsuam kom tsis tu ncua cov concentration ntawm cov piam thaj hauv cov ntshav ntawm lub plab khoob thiab tom qab noj mov. Tus neeg mob yuav tsum tau ceeb toom txog qhov kev pheej hmoo yuav txo ntshav qab zib hauv lub cev thaum haus cawv, NSAIDs, thiab thaum yoo mov.

Ib qho kev hloov kho koob tshuaj yog qhov tsim nyog rau kev tawm dag zog lub cev thiab lub siab, hloov kev noj zaub mov.

Hauv cov neeg mob uas muaj lub cev tsis zoo, nrog rau cov neeg mob uas tau txais kev noj zaub mov tsis txaus, yuav tsum tau saib xyuas thaum xaiv thawj zaug thiab txij nkawm, thiab nws cov lej, kom tsis txhob muaj ntshav qab zib.

Cov pab pawg neeg tshwj xeeb

Kev xaiv ntau ntxiv hauv cov neeg mob uas muaj ntshav qab zib hom 2 hauv kev sib xyaw nrog kev ua haujlwm raum tsis zoo yuav tsum tau ua nrog ceev faj.

Kev tswj hwm ntawm cov pa tshuaj ntawm cov tshuaj repaglinide hauv cov neeg mob uas lub siab tsis ua haujlwm tuaj yeem ua rau muaj qhov siab dua ntawm repaglinide thiab nws cov metabolites dua li ntawm cov neeg mob uas lub siab ua haujlwm. Hauv qhov no, kev teem sijhawm ntawm repaglinide yog contraindicated nyob rau hauv cov neeg mob uas muaj lub siab tsis txaus ua haujlwm (saib ntu "Contraindications"), thiab hauv cov neeg mob uas tsis muaj peev xwm ua haujlwm tsis muaj zog ntawm me me mus rau theem ntawm repaglinide yuav tsum tau siv nrog ceev faj. Lub sijhawm nruab nrab ntawm kev kho kom haum rau koob tshuaj yuav tsum tau nce ntxiv kom muaj kev txheeb xyuas tau zoo dua cov lus teb rau kev kho.

Cuam Tshuam rau kev muaj peev xwm tsav tsheb thiab ua haujlwm nrog tshuab

Lub peev xwm ntawm cov neeg mob kom mloog zoo thiab qhov nrawm ntawm cov tshuaj tiv thaiv tej zaum yuav ua rau lub sij hawm hypoglycemia thiab hyperglycemia, uas tuaj yeem ua rau muaj xwm txheej nyob rau hauv cov xwm txheej uas qhov peev xwm no tshwj xeeb tshaj yog (piv txwv li, thaum tsav tsheb lossis ua haujlwm nrog cov tshuab thiab tshuab). Cov neeg mob yuav tsum tau qhia rau kev ntsuas kom tiv thaiv kev txhim kho hypoglycemia thiab hyperglycemia thaum tsav tsheb thiab ua haujlwm nrog cov txheej txheem. Qhov no tseem ceeb tshwj xeeb tshaj yog rau cov neeg mob uas tsis muaj los yog tsawg dua cov tsos mob tshwm sim ntawm kev tsim kho tus mob hypoglycemia lossis nrog cov kev mob ntshav tsis txaus ua kom ntog mus. Hauv cov xwm txheej no, qhov ua tau ntawm cov haujlwm no yuav tsum raug txiav txim siab.

Kev taw qhia thiab contraindications

Zoo li lwm yam tshuaj, Diclinid muaj nws tus kheej qhia rau siv. Raws li tau hais los saud, nws yog tshuaj rau cov neeg mob ntshav qab zib hom II los ua kom cov ntshav qab zib. Qhia tias yav dhau los siv cov kev ua hauv kev noj zaub mov noj thiab kev ua kis las tsis muab cov nyhuv ua kom haum.

Koj tsis tuaj yeem noj cov tshuaj yog tias tus neeg mob tau mob siab rau qhov tshuaj tag nrho lossis nws cov khoom, vim qhov no tuaj yeem ua rau muaj kev tsis haum ntawm qhov txawv txav.

Cov tshuaj tsis yog kws kho rau kev kho mob ntshav qab zib mellitus ntawm thawj hom, nrog rau cov kab mob ntshav qab zib ntawm ketoacidosis, precomatosis, coma, lub siab ua haujlwm tsis txaus, lactase deficiency, rhiab rau lactose.

Daim ntawv ntawm contraindications tsis yog me me thiab nws suav nrog cov xwm txheej hauv qab no:

  • Lub sijhawm ua kom cev xeeb tub, pub mis.
  • Cov menyuam yaus lub hnub nyoog, uas ntev txog 18 xyoo.
  • Koj tsis tuaj yeem ua ke cov tshuaj nrog gemfibrozil.
  • Tshaj phais.
  • Kis tau tus kab mob pathologies.
  • Ntau yam kev raug mob hnyav.

Cov contraindications uas tau teev saud yog qhov meej. Hauv lwm cov lus, cov tshuaj tsis raug sau tseg yog tias lawv muaj keeb kwm ntawm tus neeg mob. Nrog rau lawv, cov txheeb ze contraindications tseem yuav txawv.

Qhov no txhais tau hais tias ua ntej sau ntawv yuav tshuaj, tus kws kho mob muab piv rau qhov tshwm sim ntawm cov txiaj ntsig ntawm kev kho thiab qhov pheej hmoo ntawm cov kev mob tshwm sim thiab lwm cov kev mob tshwm sim.

Tus neeg txheeb ze contraindications muaj xws li febrile syndrome, ib daim ntawv uas mob raum tsis ua hauj lwm, kev noj zaub mov tsis zoo, kev haus dej cawv, thiab cov mob hnyav ntawm tus neeg mob.

Cov tshuaj tau dhau txhua qhov kev sim tshuaj. Txawm li cas los xij, kev tshawb fawb txog hnub nyoog 18 thiab tshaj 75 tsis tau ua.

Kev daws teeb meem tshwm sim los ntawm kev siv cov tshuaj

Kev tshuaj xyuas cov neeg mob nco ntsoov tias cov tshuaj kuj pab sai sai kom txo cov suab thaj thiab txhim kho kev noj qab haus huv. Nrog rau qhov no, ntau hais txog cov kev mob tshwm sim uas tau dhau los ntawm kev siv tshuaj yeeb.

Feem ntau cov kev phiv tshuaj tiv thaiv yog ib lub xeev hypoglycemic. Hmoov tsis zoo, nws yuav luag tsis yooj yim uas tiv thaiv kom tsis txhob muaj suab thaj nce siab. Txij li thaum tus mob no nyob ntawm ntau yam: noj ntau npaum li cas ntawm cov tshuaj, kev noj zaub mov noj, ua si lub cev, kev ntxhov siab, neurosis, kev xav muaj zog, thiab lwm yam.

Cov kev mob tshwm sim yuav tshwm sim rau ntawm cov khoom noj ntawm cov khoom noj hauv lub cev: raws li tau sau tseg, qhov no yog feem ntau hypoglycemia. Raws li txoj cai, nws yog txaus noj ib qho me me ntawm carbohydrates kom ib txwm ua rau tus neeg mob kom zoo. Tsuas yog tshwj xeeb qee zaus, yuav tsum tau txais kev kho mob sai sai.

Abstract ntawm cov tshuaj sau tseg cov kev mob tshwm sim nram qab no:

  1. Ntawm ib feem ntawm cov kabmob tiv thaiv kab mob: cov tshuaj tiv thaiv tsis haum nrog dav dav, xws li vasculitis, kev tawm tsam nrog kev tshwm sim ntawm daim tawv nqaij - ua pob liab liab, khaus khaus, liab ntawm daim tawv.
  2. Kev cuam tshuam ntawm txoj hnyuv thiab lub plab zom mov, mob hauv plab, tawm tsam ntawm xeev siab thiab ntuav.
  3. Nce kev ua haujlwm ntawm daim siab enzymes, ua kom lub siab ua haujlwm tsis zoo.

Nws tau sau tseg tias kev noj tshuaj yuav tuaj yeem ua rau pom kev tsis txaus siab.

Raws li txoj cai, qhov tsos mob no yog ib ntus, ua rau tus kheej qib thaum kho. Tshwjxeeb ntawm qee qhov tsis tshua muaj, kev tshem tawm cov tshuaj yuav tsim nyog.

Cov lus qhia rau kev siv

Cov tshuaj Diclinid tsis yog panacea, nws yog ib qho ntxiv rau kev ua kom lub cev thiab ua zaub mov noj rau cov neeg mob ntshav qab zib tsawg. Tsuas yog hauv qhov no muaj peev xwm ua kom qhov kev xav tau ntawm txoj kev kho mob tuaj yeem ua tiav.

Cov tshuaj ntawm cov tshuaj yog ib txwm xaiv ib tus zuj zus. Qhov tseem ceeb tshaj plaws yog cov pib ntsuas cov ntshav qab zib. Thaum xaiv cov koob tshuaj, cov kab mob sib kis thiab lwm yam ntxiv tau ntxiv rau hauv tus account.

Cov lus qhia rau kev siv hais tias yuav tsum noj cov ntsiav tshuaj ntawm ib hlis twg ntawm ib teev ua ntej noj mov tseem ceeb. Txawm li cas los xij, koj tuaj yeem siv sijhawm ib nrab teev ua ntej noj mov.

Cov yam ntxwv ntawm kev kho los ntawm Diagninid:

  • Cov qauv tshuaj rau cov neeg mob uas tsis tau noj cov tshuaj yav dhau los kom txo cov ntshav qab zib hauv ntshav qab zib hom 2 yog 0.5 mg.
  • Yog tias tus neeg mob tau ua yav dhau los noj ib qho tshuaj hypoglycemic, ces kev muab tshuaj thawj zaug yog 1 mg.
  • Raws li qhov tsim nyog, nws pom zoo hloov kho lub koob tshuaj ib zaug txhua 7-14 hnub.
  • Kev hais lus ntawm qhov nruab nrab, tom qab txhua qhov nce, cov koob tshuaj yog 4 mg ntawm cov tshuaj, uas tau muab faib ua peb koob tshuaj ib hnub.
  • Qhov ntau kawg ntawm cov tshuaj yog 16 mg.

Yog hais tias tus neeg mob noj lwm tus neeg mob hypoglycemic thiab yuav tsum tau hloov rau ib qho laj thawj kev kho mob, ces kev hloov mus rau Diagninid yog ua tiav yam tsis muaj kev cuam tshuam. Txij li nws tsis tuaj yeem tsim qhov tseeb qhov sib piv ntawm ob cov tshuaj, tab sis thawj koob tsis ntau tshaj 1 mg.

Cov teev koob tshuaj tau muab tuav tswj tsis hais txoj kev tswj hwm tshuaj. Tshwj xeeb, ob qho tib si hauv monotherapy thiab hauv txoj kev kho mob ntawm hom 2 mob ntshav qab zib mellitus. Tus nqi yog los ntawm 200 rubles.

Cov ntsuas ntawm Diaglinide, cov nqi thiab tshuaj xyuas

Diaglinide muaj ob peb analogues, thiab NovoNorm, zoo li Repaglinide xa mus rau lawv. Tus nqi ntawm NovoNorm pauv ntawm 170 txog 250 rubles. Cov tshuaj muaj peev xwm yuav tau ntawm khw muag tshuaj lossis chaw muag tshuaj kiosk, nws raug tsocai mus yuav cov tshuaj hauv Is Taws Nem.

Cov tshuaj tau muab khaws cia rau hauv qhov chaw tsaus, tsis nkag rau cov me nyuam me. Lub txee lub neej ntawm cov tshuaj yog ob xyoos.

Tom qab kuaj xyuas ntau cov kev soj ntsuam ntawm cov ntshav qab zib, peb tuaj yeem xaus tias cov tshuaj muaj txiaj ntsig nrog lub luag haujlwm, pab ua kom cov suab thaj li qub thiab ua rau nws nyob ntawm lub hom phiaj. Txawm li cas los xij, tus neeg mob yuav tsum tau siv zog hauv daim qauv ntawm kev noj haus thiab ua kom lub cev.

Tseem muaj kev tshuaj xyuas tsis zoo, uas ua rau dhau los ntawm kev tsis ua raws li qhov pom zoo ntau npaum ntawm cov tshuaj, nrog rau kev noj haus tsis raug.

Thiab koj tuaj yeem qhia dab tsi txog cov tshuaj no? Koj puas tau noj cov ntsiav tshuaj, thiab ua li cas lawv ua haujlwm hauv koj qhov xwm txheej?

Cia Koj Saib