Humalog - cov lus qhia ua haujlwm rau kev siv
Cov neeg mob ntshav qab zib muaj ntau zuj zus nyob rau txhua xyoo. Ua raws li kev noj haus kom nruj thiab kho cov tshuaj, muaj txoj hmoo rov qab los tag nrog cov mob sib khuav.
Nrog tus mob ntshav qab zib hom 1, yuav rov qab tsis tau tag. Lub txiav ua tsis tiav cov tshuaj hormone insulin, uas koom nrog hauv txhua txoj kev zom zaub mov hauv tib neeg cov plab hnyuv siab raum thiab cov ntaub so ntswg.
Tab sis xaiv cov tshuaj insulin kho raug ua haujlwm rau ntawm lub txiav. Cov tshuaj hormones luv thiab ntev yog tsim los. Nrog lub ntsej muag dhia hauv qab zib, ultra-luv luv insulins siv. Humalog thiab Novorapid muaj qhov kev txiav txim siab luv luv.
Qhov zoo thiab qhov tsis zoo
Cov koob tshuaj thiab lub sijhawm ntawm luv luv insulin yog suav ua ntej. Tus neeg mob yuav tsum ua raws nraim li cov lus qhia noj haus, noj cov tshuaj kom raws sijhawm. Cov tshuaj insulin luv luv pib ua tom qab 30-40 feeb ntawm kev tswj hwm. Cov tshuaj ultrashort pib ua yeeb yaj kiab tom qab 10-20 feeb. Nws yog qhov tsim nyog rau kis mob uas tsis tau npaj cia. Ultrashort insulin yog tsim los ua kom yooj yim rau lub neej muaj ntshav qab zib.
Qhov tsis zoo ntawm Humalog thiab Novorapid yog tias nws yog qhov muaj teeb meem los xam tus nqi ntawm cov carbohydrates xav tau los ua kom ib txwm muaj suab thaj. Cov tshuaj tau nrawm heev. Yog hais tias lub cev tsis tswj xyuas kom tau txais qhov tsim nyog ntawm cov piam thaj, ntshav qab zib tsawg tshwm sim. Hauv qhov no, kev siv cov tshuaj insulin luv luv thiab kev noj haus yog hom kev tsim nyog dua.
Ultrashort analogues ntawm tib neeg cov tshuaj hormones yog tsim los tswj cov qib ntawm cov kua nplaum tom qab kev noj zaub mov carbohydrates ceev. Tab sis Humalog thiab Novorapid tsis muaj peev xwm yuav nqus tau los ntawm lub cev sai dua li cov suab thaj. Kev noj cov tshuaj no tsis txwv ib qho kev noj zaub mov kom tsawg.
Txog cov zaub mov muaj dej qis, kev siv cov insulin luv luv yog muab. Ultra-short-acting siv yeeb siv tshuaj yuav tsum tau ceev cov ntshav qab zib kom dhia ceev hauv cov ntshav qabzib.
Lizpro thiab aspart muaj zog dua li cov tshuaj lom neeg luv luv ua ntu ntev los ntawm 1.5-2.5 zaug. Qhov ntau npaum li cas ntawm cov tshuaj ultrashort qis dua hauv kev sib piv nrog luv luv insulin. Kev noj tshuaj ntau dhau hle dhau yog qhov txaus ntshai nrog qhov txo qis hauv cov piam thaj hauv cov ntshav.
Muaj qee zaus, cov neeg mob ntshav qab zib yog cov tshuaj tiv thaiv luv luv. Cov tshuaj hormone yog nqus los ntawm lub cev tsuas yog 1.5 teev tom qab kev coj. Kev siv ntawm kev npaj ultrashort yog qhia rau cov neeg mob ntawd.
Lub tswv yim ntawm cov kws kho mob - uas zoo dua?
Raws li kws kho mob, cov tshuaj tsis muaj qhov sib txawv. Tab sis Novorapid yog qhov tshuaj nkaus xwb uas tau muab pov thawj tsis muaj mob rau cov poj niam cev xeeb tub. Cov kws kho mob tseem ntseeg hais tias Humalog tseem muaj zog dua Novorapid. Cov tshuaj Humalog txo cov suab thaj ntau 2,5 zaug ntau dua li cov tshuaj hormones luv novoropid 1.5 npaug. Yog li, cov tshuaj ntau npaum li cas thawj ib cov tshuaj tsawg dua zaum ob.
Cov tshuaj yeeb yam nrov tshaj plaws hauv kev ua yog Apidra. Cov tshuaj yog muab rov qab los ntawm tib neeg cov tshuaj insulin thiab ua 10 feeb tom qab kev tswj hwm. Cov tshuaj nquag yog glulisin.
Lwm cov analogues:
Kev kho rau txhua tus mob ntshav qab zib yog xaiv tau ib tus zuj zus los ntawm kws kho mob. Tus nqi qeb ntawm cov tshuaj nyob rau tib theem. Raws li cov neeg mob, tsis muaj qhov sib txawv hauv kev hloov ntawm ib qho tshuaj hormone mus rau lwm qhov. Ultrashort insulins yog ua ke nrog cov tshuaj hormones ntev. Hloov rau cov khoom noj uas pom zoo, lispro thiab aspart yog hloov nrog cov yeeb yam luv-luv.
Qhia me ntsis
Cov lus qhia txog kev siv tshuaj insulin Humalog yog qhov hluav taws xob heev, thiab cov ntu piav qhia txog kev phiv thiab cov lus qhia rau kev siv nyob ntau dua ib kab lus. Cov lus piav qhia ntev ntev uas sib xyaw nrog qee cov tshuaj tau pom los ntawm cov neeg mob yog lus ceeb toom txog kev phom sij ntawm kev coj lawv.Qhov tseeb, txhua yam muaj qhov sib txawv: ib qho loj, cov lus qhia ntxaws ntxaws - cov ntaub ntawv pov thawj ntawm ntau yam kev sim siab tias cov tshuaj no thev taus zoo.
Mob ntshav qab zib thiab siab surges yuav yog ib yam dhau los
Mob ntshav qab zib yog qhov ua rau ze li ntawm 80% ntawm tag nrho cov cwj nrag thiab txiav taws. 7 ntawm 10 leej neeg tuag vim txhaws ntawm cov hlab ntsha hauv plawv lossis paj hlwb. Yuav luag txhua qhov teeb meem, qhov laj thawj rau qhov txaus ntshai kawg no yog qhov qub - ntshav qab zib siab.
Cov piam thaj tuaj yeem thiab yuav tsum tau sib khob, tsis muaj dab tsi. Tab sis qhov no tsis kho tus kab mob nws tus kheej, tab sis tsuas yog pab txhawm rau txhawm rau tshawb xyuas, thiab tsis yog qhov ua kom muaj tus kab mob.
Cov tshuaj nkaus xwb uas raug pom zoo rau kev kho mob ntshav qab zib thiab nws kuj yog siv los ntawm endocrinologist hauv lawv txoj haujlwm yog qhov no.
Qhov ua tau zoo ntawm cov tshuaj, suav raws li tus qauv txheej txheem (tus naj npawb ntawm cov neeg mob uas tau zoo mus rau tag nrho cov neeg mob hauv pawg 100 ntawm cov neeg tau txais kev kho mob) yog:
- Li qub ntawm qab zib - 95%
- Kev tshem tawm ntawm cov hlab ntshav thrombosis - 70%
- Ntaus tau ntawm lub plawv dhia muaj zog - 90%
- Kev tshem tawm ntshav siab - 92%
- Ntxiv dag zog rau nruab hnub, txhim kho pw tsaug zog thaum hmo ntuj - 97%
Cov neeg tsim khoom tsis yog lub koom haum ua lag luam thiab tau nyiaj peev nrog kev txhawb nqa los ntawm lub xeev. Yog li ntawd, tam sim no txhua tus neeg nyob hauv muaj qhov zoo.
Humalogue tau txais kev pom zoo rau kev siv ntau dua 20 xyoo dhau los, tam sim no nws tuaj yeem ntseeg tau hais tias qhov tshuaj insulin no muaj kev nyab xeeb ntawm kev siv tshuaj. Nws tau txais kev pom zoo rau kev siv los ntawm ob tus neeg laus thiab menyuam yaus, tuaj yeem siv rau txhua tus neeg mob, nrog rau qhov tsis muaj suab yam tshuaj: hom 1 thiab ntshav qab zib hom 2, phais mob pancreatic.
Cov ntaub ntawv dav dav txog qhov Humalogue:
Kev piav qhia | Cov tshuaj daws teeb meem. Nws yuav tsum tau tshwj xeeb cia khoom, yog tias lawv tau ua txhaum, nws tuaj yeem poob nws cov khoom yam tsis muaj kev hloov pauv lub ntsej muag, yog li cov tshuaj muaj peev xwm tsuas yuav hauv khw muag tshuaj. |
Lub hauv paus ntsiab lus ntawm kev khiav haujlwm | Muab cov piam thaj rau hauv cov ntaub so ntswg, txhim kho kev hloov pauv ntawm cov piam thaj hauv daim siab, thiab tiv thaiv kev cuam tshuam ntawm cov rog. Qhov kev txiav ntshav qab zib tau pib ua ntej tshaj li cov tshuaj insulin luv luv, thiab kav ntev dua. |
Daim Ntawv | Kev daws nrog kev saib xyuas ntawm U100, kev tswj hwm - subcutaneous lossis intravenous. Ntim hauv lub thawv ntawv lossis cov ntawv xev xim siv uas siv pov tseg. |
Chaw tsim tshuaj paus | Cov kev daws teeb meem tsuas yog tsim los ntawm Lilly Fabkis, Fab Kis. Ntim yog tsim nyob rau hauv Fabkis, Tebchaws Asmeskas thiab Russia. |
Nqi | Hauv Lavxias, tus nqi ntawm ib pob khoom muaj 5 cartridges ntawm 3 ml txhua yog li 1800 rubles. Hauv Tebchaws Europe, tus nqi rau cov ntim zoo sib xws yog txog tib yam. Hauv Teb Chaws Asmeskas, cov tshuaj insulin no yuav luag kim 10 npaug. |
Cov Khoom Qhia |
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Cov Yuav Tsum Tau Ua | Cov tib neeg tawm tsam cov tshuaj insulin lyspro lossis cov ntu pabcuam. Ntau zaus qhia nyob rau hauv kev ua xua ntawm qhov chaw txhaj tshuaj. Nrog rau qhov mob qis qis, nws hla dhau ib lub lim tiam tom qab hloov mus rau qhov tshuaj insulin no. Cov mob hnyav yog muaj tsawg, lawv xav hloov Humalog nrog analogues. |
Cov yam ntxwv ntawm kev hloov mus rau Humalog | Thaum xaiv koob tshuaj, kev ntsuas ntau dua ntawm glycemia, yuav tsum tau muaj kev sib tham txog kev kho mob tas li. Raws li txoj cai, tus mob ntshav qab zib xav tau tsawg dua Humalog chav nyob rau 1 XE dua li neeg. Kev xav tau ntau ntxiv rau lub cev yog pom nyob hauv ntau yam kabmob, kev nyuaj siab dhau ntawm lub cev, thiab kev tawm dag zog. |
Noj ntau dhau | Tshaj dhau cov koob tshuaj no ua rau cov ntshav qab zib tsawg. Txhawm rau tshem tawm nws, koj xav tau kev txais tos. Cov mob hnyav yuav tsum tau kho mob sai. |
Co-administration nrog lwm cov tshuaj | Humalog tuaj yeem txo qis kev ua haujlwm:
Yog tias cov tshuaj no tsis tuaj yeem hloov los ntawm lwm tus, qhov tshuaj ntawm Humalog yuav tsum tau kho ib ntus. |
Cia | Hauv lub tub yees - 3 xyoos, nyob rau ntawm chav tsev kub - 4 lub lis piam. |
Ntawm cov kev mob tshwm sim, hypoglycemia thiab kev fab tshuaj tsis haum yog feem ntau pom (1-10% ntawm neeg mob ntshav qab zib). Tsawg dua 1% ntawm cov neeg mob tsim muaj lipodystrophy ntawm thaj chaw txhaj tshuaj. Qhov ntau zaus ntawm lwm cov kev tsis sib haum yog tsawg dua 0.1%.
Qhov Tseem Ceeb Tshaj Txog Neeg Yuav Tsum
Nyob hauv tsev, Humalog tau txais kev tso cai subcutaneously nrog ib rab koob xaum qhuav los yog. Yog tias muaj mob loj heev yuav tsum raug tshem tawm, kev tswj hwm cov tshuaj no kuj tuaj yeem ua rau hauv chaw kho mob. Hauv qhov no, nquag tswj cov piam thaj yog qhov tsim nyog kom tsis txhob noj ntau dhau.
Cov tshuaj nquag ua haujlwm ntawm cov tshuaj yog insulin lispro. Nws txawv ntawm tib neeg cov tshuaj hormones hauv kev npaj cov amino acids hauv cov qauv molecule. Xws li kev hloov kho tsis tiv thaiv cov cell receptors los ntawm kev paub txog cov tshuaj hormones, yog li lawv yooj yim dhau suab thaj rau lawv tus kheej. Qhov humalogue tsuas muaj cov tshuaj insulin monomers - ib qho, tsis txuas yam tsis txawv. Vim tias qhov no, nws yog nqus tau nrawm thiab tusyees, pib ua haujlwm kom txo cov piam thaj sai dua li cov tshuaj insulin tsis haum.
Qhov tshuaj tiv thaiv tshuaj yog qhov yeeb tshuaj luv dua li, piv txwv, lossis. Raws li kev faib tawm, nws tau xa mus rau cov tshuaj insulin sib piv nrog cov kev ua kom haum. Pib ntawm nws txoj haujlwm tau nrawm dua, li 15 feeb, yog li cov neeg mob ntshav qab zib tsis tas yuav tos kom txog thaum cov tshuaj ua haujlwm, tab sis koj tuaj yeem npaj zaub mov noj tom qab txhaj tshuaj. Ua tsaug rau qhov tsis txaus no, nws yuav yooj yim rau kev npaj zaub mov noj, thiab qhov kev pheej hmoo tsis nco qab cov zaub mov tom qab kev txhaj tshuaj yog txo qis dua.
Rau kev tswj cov glycemic zoo, cov neeg sawv cev ceev ceev yuav tsum tau ua ke nrog kev siv. Tib qho kev zam tsuas yog kev siv lub tshuab nqus dej twj tso kua mis rau ntawm lub sijhawm txuas ntxiv.
Xaiv xaiv
Kev noj tshuaj Humalog ntau nyob ntawm ntau yam thiab txiav txim siab ntawm tus kheej rau txhua tus mob ntshav qab zib. Kev siv cov qauv txheem yog tsis pom zoo, vim tias lawv ua rau kev mob ntshav qab zib hnyav dua. Yog tias tus neeg mob ua raws li cov zaub mov tsis zoo, lub cev ntawm Humalog yuav tsawg dua li tus qauv ntawm cov thawj coj tuaj yeem muab tau. Hauv qhov no, nws pom zoo kom siv cov tshuaj insulin uas tsis muaj zog tuaj.
Ultrashort cov tshuaj hormones muab cov nyhuv loj tshaj. Thaum hloov mus rau Humalog, nws qhov kev pib noj tshuaj yog xam raws li 40% ntawm kev siv insulin luv luv. Raws li cov txiaj ntsig ntawm glycemia, ntau npaum li cas tau kho. Qhov xav tau qhov nruab nrab ntawm kev npaj rau ib khob cij yog 1-1.5 units.
Cov yam ntxwv ntawm insulin niaj hnub
Muaj qee qhov kev txwv ntawm kev siv ntawm cov tshuaj insulin ntawm tib neeg, piv txwv li, qhov pib qeeb ntawm qhov kis tus kab mob (tus mob ntshav qab zib yuav tsum tau txhaj tshuaj 30-40 feeb ua ntej noj mov) thiab lub sijhawm ua haujlwm ntev dhau lawm (txog 12 teev), uas tuaj yeem dhau los ua qhov yuav tsum tau ua kom ncua qis rau lub qog ntshav qab zib.
Thaum kawg ntawm lub xyoo pua xeem, qhov kev xav tau tshwm sim los tsim cov tshuaj insulin uas yuav tso tau qhov tsis muaj qhov tsis txaus no. Cov yeeb yaj kiab luv ua haujlwm pib tsim muaj nrog luv-lub neej luv luv tau.
Qhov no coj lawv los ze zog rau cov khoom ntawm insulin haiv neeg, uas tuaj yeem ua rau tsis muaj zog tom qab 4-5 feeb tom qab nkag rau hauv cov hlab ntshav.
Peakless cov kua dej tsis sib xws tuaj yeem sib txig sib luag thiab ntseeg tau los ntawm cov roj ntsha subcutaneous thiab tsis ua rau lub cev tsis muaj ntshav ntau.
Xyoo tsis ntev los no, tau muaj kev pom zoo tseem ceeb hauv chaw muag tshuaj, vim nws sau tseg:
- qhov kev hloov ntawm acidic daws teeb meem rau qhov nruab nrab,
- txais tib neeg cov tshuaj insulin siv cov thev naus laus zis DNA technology,
- kev tsim cov siab zoo hloov pauv insulin nrog cov yam ntxwv pharmacological tshiab.
Insulin analogs pauv hloov lub sijhawm ntawm qhov kev ua ntawm tib neeg los ua tib neeg los muab ib tus neeg physiological mus kom ze rau kev kho thiab qhov yooj yim tshaj plaws rau cov ntshav qab zib.
Cov tshuaj ua rau nws ua tiav kom ua tiav txoj kev sib txig sib luag ntawm kev pheej hmoo ntawm kev poob ntshav qab zib thiab kev ua tiav ntawm lub hom phiaj glycemia.
Cov tshuaj hnub tshiab ntawm cov tshuaj insulin raws li lub sijhawm ntawm nws qhov kev txiav txim siab feem ntau muab faib ua:
- ultrashort (Humalog, Apidra, Penfill), thiab
- lub sijhawm ntev (Daim roj Hmo, Levemir Penfill).
Tsis tas li ntawd, muaj cov tshuaj sib xyaw ua ke hloov pauv, uas yog ib qho sib xyaw ntawm cov tshuaj ultrashort thiab lub cev ntev nyob hauv ib qho kev sib piv: Penfill, Humalog sib tov 25.
Humalog (lispro)
Hauv cov qauv ntawm cov tshuaj insulin no, txoj haujlwm ntawm kab thiab lysine tau hloov pauv. Qhov sib txawv ntawm cov tshuaj thiab cov tib neeg kho cov tshuaj lom neeg tsis muaj zog yog qhov tsis muaj qhov txawv txav ntawm cov koom haum sib txuas. Hauv kev pom ntawm qhov no, lispro tuaj yeem nqus tau sai rau hauv cov hlab ntshav ntawm cov ntshav qab zib.
Yog tias koj txhaj tshuaj rau hauv tib lub tshuaj thiab tib lub sijhawm, Tom qab ntawd Humalog yuav muab qhov siab tshaj 2 zaug sai dua. Qhov no cov tshuaj hormones yog tshem tawm ntau nrawm dua thiab tom qab 4 teev nws qhov kev kub siab tuaj txog nws qib pib. Qhov kev cia siab ntawm cov tshuaj insulin rau tib neeg yuav raug tswj nyob hauv 6 teev.
Muab piv rau Lyspro nrog cov tshuaj insulin luv luv, peb tuaj yeem hais tias tus qub tuaj yeem txwv kev tsim cov piam thaj los ntawm daim siab ntau dua.
Muaj lwm qhov zoo ntxiv ntawm cov tshuaj Humalog - nws yog qhov kom paub tseeb tseeb dua ntxiv thiab tuaj yeem pab lub sijhawm noj tshuaj hloov kho mus rau txoj kev noj zaub mov kom haum. Nws yog tus yam ntxwv los ntawm qhov tsis muaj qhov hloov ntawm lub sijhawm ua haujlwm los ntawm kev nce hauv lub ntim ntawm cov tshuaj nkag.
Siv tib neeg cov tshuaj insulin, lub sijhawm ua haujlwm ntawm nws txoj haujlwm yuav txawv nyob ntawm koob tshuaj. Nws yog los ntawm qhov no hais tias qhov nruab nrab li ntawm 6 txog 12 teev tshwm sim.
Nrog rau kev nce ntxiv hauv cov tshuaj ntawm cov tshuaj insulin Humalog, lub sijhawm ua haujlwm nws tseem yuav luag nyob rau tib theem thiab yuav yog 5 teev.
Nws ua raws tias nrog kev nce ntxiv ntawm cov koob tshuaj lispro, qhov kev pheej hmoo ntawm hypoglycemia tsis nce.
Aspart (Novorapid Penfill)
Cov tshuaj insulin no tuaj yeem ua rau zoo tiav raws li cov tshuaj insulin txaus rau kev noj zaub mov. Nws lub sijhawm luv luv ua rau muaj kev cuam tshuam tsis tshua zoo rau ntawm kev noj mov, uas ua rau nws muaj peev xwm ua kom tiav kev tswj xyuas kom ua tiav cov ntshav qab zib.
Yog tias peb piv cov txiaj ntsig ntawm kev kho mob nrog insulin analogues nrog cov neeg ua yeeb yam luv luv rau tib neeg, nws qhov tseem ceeb hauv kev tswj hwm tau zoo ntawm cov ntshav qab zib tom qab qib siab yuav raug sau tseg.
Ua ke nrog kev kho mob nrog Detemir thiab Aspart muab lub sijhawm:
- yuav luag 100% normalize rau daim ntawv qhia txhua hnub ntawm cov tshuaj insulin,
- txhawm rau txhim kho qib ntawm glycosylated hemoglobin,
- txo txoj kev pheej hmoo ntawm kev txhim kho hypoglycemic,
- txo cov kev ua kom ntau thiab cov ntsiab lus ntawm cov ntshav qab zib ntawm ntshav qab zib.
Nws yog qhov tsim nyog hais tias thaum lub sij hawm kho nrog basal-bolus insulin analogues, qhov nruab nrab ntawm lub cev qhov hnyav tau qis dua qis dua rau tag nrho lub sijhawm ntawm kev tshuaj xyuas zoo.
Glulisin (Apidra)
Tus tib neeg cov tshuaj insulin analog Apidra yog cov tshuaj tiv thaiv ultra-luv. Raws li nws cov pharmacokinetic, cov yam ntxwv pharmacodynamic thiab kev nyab xeeb ntawm lub cev, Glulisin yog qhov sib npaug nrog Humalog. Hauv nws qhov kev ua kom zoo thiab metabolic, yam tshuaj no tsis txawv ntawm tib neeg insulin. Ua tsaug rau qhov no, nws yog qhov tsim nyog siv nws rau lub sijhawm ntev, thiab nws muaj kev nyab xeeb kiag li.
Raws li txoj cai, Apidra yuav tsum tau siv nrog:
- ntev insulin tib neeg
- basal insulin analogue.
Tsis tas li ntawd, cov tshuaj yeeb tshuaj yog tus cwj pwm los ntawm kev pib ua haujlwm sai thiab nws lub sijhawm luv dua li ib txwm muaj tib neeg lawm. Nws tso cai rau cov neeg mob ntshav qab zib kom pom qhov ua kom yooj yim hauv kev siv nws nrog zaub mov ntau dua li tib neeg kev noj tshuaj.Cov tshuaj Insulin pib nws cov nyhuv tam sim ntawd tom qab tswjhwm, thiab cov ntshav qab zib cov ntshav poob 10-20 feeb tom qab Apidra tau txhaj tshuaj subcutaneously.
Txhawm rau kom tsis txhob mob ntshav qab zib hauv cov neeg laus, cov kws kho mob pom zoo kom qhia cov tshuaj tam sim ntawd tom qab noj mov lossis hauv tib lub sijhawm. Lub sij hawm txo qis ntawm cov tshuaj no yuav pab kom tsis txhob muaj qhov hu ua "overlay" nyhuv, uas ua rau nws tiv thaiv kom tsis txhob mob ntshav qab zib.
Nws tuaj yeem siv tau rau cov uas rog dhau los, vim tias nws siv tsis ua rau nce ntxiv. Cov tshuaj yog tus cwj pwm los ntawm kev pib sai ntawm qhov siab tshaj plaws piv nrog lwm hom kev ua haujlwm tsis tu ncua thiab lispro.
Apidra yog qhov zoo rau ntau qib ntawm kev hnyav dhau vim nws txoj kev hloov pauv ntau. Hauv visceral hom kev rog, qhov nqus ntawm cov tshuaj tuaj yeem sib txawv, ua rau nws nyuaj rau kev tswj hwm glycemic.
Kev tshuaj xyuas (Levemir Penfill)
Levemir Penfill yog ib qho tshuaj tiv thaiv ntawm tib neeg cov tshuaj insulin. Nws muaj lub sijhawm ua haujlwm nruab nrab thiab tsis muaj peaks. Qhov no pab kom cov hauv paus tswj glycemic tswj thaum nruab hnub, tab sis raug siv ob npaug.
Thaum muab tshuaj subcutaneously, Detemir tsim cov tshuaj uas khi rau cov ntshiab albumin hauv cov kua dej interstitial. Tom qab hloov mus los ntawm phab ntsa capillary, insulin rov khi rau albumin hauv cov hlab ntshav.
Hauv kev npaj, tsuas yog cov seem dawb yog kev ua haujlwm biologically. Yog li ntawd, khi rau albumin thiab nws cov hniav qeeb tau muab kev ua haujlwm ntev thiab tsis siab.
Levemir Penfill insulin ua rau tus neeg mob ntshav qab zib kom zoo thiab ua tiav nws txoj kev xav tau tag nrho cov tshuaj insulin basal. Nws tsis muab kev tshee ua ntej ua haujlwm subcutaneous.
Glargin (Lub Teeb)
Glargin insulin hloov pauv yog ultra-nrawm. Cov tshuaj no tuaj yeem ua tau zoo thiab ua kom tiav nyob hauv ib puag ncig acidic me ntsis, thiab hauv nruab nrab nruab nrab (hauv cov rog muaj roj) nws yog cov dej tsis zoo.
Tam sim ntawd tom qab kev tswj hwm subcutaneous, Glargin nkag mus rau hauv qhov kev tiv thaiv nruab nrab nrog kev tsim cov microprecipitation, uas yog qhov tsim nyog rau kev tso tawm ntxiv ntawm cov tshuaj hexamers thiab lawv cais ua rau insulin hormone monomers thiab dimers.
Vim tias txoj kev nqus thiab maj mam khiav ntawm Lantus rau hauv cov ntshav ntawm tus neeg mob ntshav qab zib, nws cov ntshav ncig hauv cov channel tshwm sim hauv 24 teev. Qhov no ua rau nws muaj peev xwm tso cov tshuaj insulin analogues ib zaug ib hnub.
Thaum cov nqi me me ntawm zinc ntxiv, crystallization ntawm Lantus insulin hauv subcutaneous cov ntaub so ntswg txheej yog paub tseeb tias, uas ntxiv lengthens nws lub sijhawm nqus. Kiag li ntawm tag nrho cov kev zoo ntawm cov tshuaj no lav nws cov ntaub ntawv du thiab tsis muaj dab tsi.
Glargin pib ua haujlwm tom qab 60 feeb tom qab txhaj tshuaj subcutaneous. Nws txoj kev xav nyob ruaj khov hauv tus neeg mob ntshav plasma tuaj yeem pom tom qab 2-4 teev txij li lub sijhawm muab tshuaj thawj zaug.
Tsis hais txog lub sijhawm txhaj tshuaj ntawm cov tshuaj no ultrafast (yav sawv ntxov lossis yav tsaus ntuj) thiab qhov chaw txhaj tshuaj (lub plab, caj npab, ceg), lub sijhawm uas raug rau lub cev yuav yog:
- nruab nrab - 24 teev
- qhov siab tshaj plaws - 29 teev.
Kev hloov pauv ntawm cov tshuaj insulin Glargin tuaj yeem hloov kho lub cev ntawm lub cev hormone hauv nws qhov kev ua haujlwm siab, vim hais tias cov tshuaj:
- zoo txhawb kev noj cov piam thaj los ntawm cov ntaub so ntswg ib feem ntau nyob ntawm insulin (tshwj xeeb tshaj yog cov rog thiab cov leeg),
- inhibits gluconeogenesis (txo qis).
Tsis tas li ntawd, cov tshuaj cuam tshuam rau cov txheej txheem ntawm kev sib cais ntawm cov ntaub so ntswg adipose (lipolysis), protein decomposition (tiv thaiv kab mob), thaum ua kom cov nqaij ua haujlwm ntau lawm.
Kev tshawb fawb txog kev kho mob ntawm Glargin's pharmacokinetics tau qhia tias tsis muaj kev faib tawm ntau kawg ntawm cov tshuaj no ua rau nws muaj peev xwm yuav luag 100% mimic qhov pib ntawm kev tsim cov tshuaj endogenous hormone insulin hauv 24 teev. Nyob rau tib lub sijhawm, qhov ntxim nyiam ntawm kev txhim kho hypoglycemic tej yam kev mob thiab cov ntshav siab ntxiv hauv cov ntshav qab zib kom tsawg.
Neej Neeg tshaj 25
Cov tshuaj no yog kev sib xyaw uas muaj:
- 75% tiv thaiv kev ncua ntawm cov tshuaj hormones lispro,
- 25% insulin Humalog.
Qhov no thiab lwm yam tshuaj insulin kuj tseem ua ke raws li lawv qhov kev tso tawm. Lub sijhawm zoo tshaj plaws ntawm cov tshuaj tau muab vim muaj cov txiaj ntsig ntawm kev tiv thaiv kev tiv thaiv kev cuam tshuam ntawm cov tshuaj lyspro, uas ua rau nws tuaj yeem rov ua lub hauv paus pib ntawm cov tshuaj hormone.
Qhov seem 25% ntawm lispro insulin yog ib qho kev tiv thaiv nrog lub sijhawm luv luv, uas muaj cov txiaj ntsig zoo ntawm glycemia tom qab noj mov.
Nws yog ib qho tseem ceeb tshaj plaws tias lub Humalog hauv cov lus sib xyaw ua tiav cuam tshuam rau lub cev tau nrawm dua piv nrog cov tshuaj hormones luv luv. Nws muab kev tswj siab tshaj plaws ntawm postpradial glycemia thiab vim li ntawd nws cov ntaub ntawv qhia tau ntau physiological thaum piv nrog luv luv ua yeeb yam insulin.
Cov tshuaj insulins tshwj xeeb yog pom zoo rau cov neeg muaj ntshav qab zib hom 2. Pab pawg no suav nrog cov neeg laus laus uas, raws li txoj cai, raug kev txom nyem los ntawm teeb meem nco. Tias yog vim li cas qhov kev qhia ntawm cov tshuaj hormones ua ntej noj mov lossis tam sim ntawd tom qab nws pab txhim kho kev ua neej zoo ntawm cov neeg mob ntawd.
Cov kev tshawb fawb txog kev noj qab haus huv ntawm cov neeg mob ntshav qab zib nyob hauv cov pab pawg hnub nyoog txij li 60 txog 80 xyoo uas siv cov tshuaj Humalog sib xyaw 25 qhia tau hais tias lawv tswj tau txais cov txiaj ntsig zoo rau cov metabolism hauv kev noj haus. Hauv kev coj los tswj cov tshuaj ua ntej thiab tom qab noj mov, cov kws kho mob tau tswj hwm kom maj mam nce thiab ua rau lub cev tsis muaj ntshav qab zib tsawg.
Cov neeg mob ntshav qab zib feem ntau yuav tsum siv cov tshuaj insulin-uas muaj.
Cov no suav nrog Lizpro insulin, uas yog siv dav dav siv los tswj ntshav qab zib.
Txhawm rau kom nkag siab cov ntsiab cai ntawm kev kho nrog nws cov kev pab, cov neeg mob yuav tsum paub lub ntsiab tseem ceeb ntawm cov tshuaj no.
Tus yam ntxwv dav
Lub npe lag luam rau cov tshuaj yog Humalog Mix. Nws yog nce raws li ib qho kab xev ntawm tib neeg cov kua dej. Cov tshuaj muaj cov nyhuv hypoglycemic, pab kom nrawm rau kev ua kom zoo ntawm cov piam thaj, thiab kuj tswj cov txheej txheem ntawm nws qhov kev tso tawm. Cov cuab yeej yog kev ua haujlwm ob-theem txhaj tshuaj.
Ntxiv rau cov tshuaj yeeb dej caw tseem ceeb, muaj pes tsawg leeg muaj cov khoom sib xyaw ua ke:
- metacresol
- glycerol
- sodium hydroxide nyob rau hauv daim ntawv ntawm tov (los yog hydrochloric acid),
- zinc oxide
- sodium heptahydrate hydrogen phosphate,
- dej.
Txhawm rau siv cov tshuaj no, koj xav tau kev teem caij ntsib kws kho mob nrog cov lus qhia meej. Nws tsis tuaj yeem yuav tsum kho qhov kev noj tshuaj lossis lub sijhawm siv rau ntawm koj tus kheej.
Pharmacological kev ua thiab kev ntsuas
Qhov kev ua haujlwm ntawm hom insulin no zoo ib yam li lwm yam tshuaj nyob rau hauv insulin. Kev nkag mus rau hauv lub cev, cov tshuaj muaj tshuaj txuam nrog kev ua haujlwm ntawm cov cell ua ke, yog li txhawb qhov nqus ntawm cov piam thaj.
Cov txheej txheem ntawm nws nqus los ntawm plasma thiab faib tawm hauv cov nqaij yog nrawm. Qhov no yog lub luag haujlwm ntawm insulin Lizpro nyob rau hauv kev cai ntawm qab zib.
Qhov thib ob ntawm nws cov nyhuv rau lub cev yog qhov txo qis hauv cov piam thaj los ntawm daim siab ua haujlwm. Hauv qhov no, ntau dhau ntawm cov piam thaj tsis nkag rau cov ntshav. Raws li qhov no, nws tuaj yeem hais tias qhov tshuaj Humalog muaj cov nyhuv hypoglycemic nyob rau hauv ob qho kev qhia.
Qhov insulin hom no ua haujlwm sai thiab ua haujlwm 15 feeb tom qab kev txhaj tshuaj. Qhov no txhais tau hais tias cov khoom no tau nqus sai sai los ntawm lub cev. Vim tias cov yam ntxwv no, nws raug tso cai rau siv cov tshuaj yuav luag ua ntej noj mov.
Tus nqi ntawm kev nqus tau cuam tshuam los ntawm qhov chaw txhaj tshuaj.Yog li, koj yuav tsum tau txhaj tshuaj, tsom rau cov lus qhia rau cov tshuaj.
Nws yog qhov sib npaug tseem ceeb kom ua raws li cov lus pom zoo rau Lizpro insulin thaum txiav txim siab ntawm nws txoj kev siv. Cov tshuaj muaj cov nyhuv zoo, yog li nws siv tsuas yog tso cai raws li kev taw qhia. Yog tias koj siv cov tshuaj no yam tsis tsim nyog, koj tuaj yeem ua kev puas tsuaj rau koj lub cev.
Cov ntsiab lus rau kev teem caij Humalog muaj xws li:
- thawj hom ntshav qab zib
- hyperglycemia, cov tsos mob ntawm uas tsis abate nrog kev siv lwm yam tshuaj,
- hom ob ntawm cov ntshav qab zib mellitus (hauv qhov tsis muaj tshwm sim los ntawm kev siv tshuaj yeeb rau kev tswj hwm qhov ncauj),
- kev npaj phais mob ntshav qab zib rau cov neeg mob ntshav qab zib,
- qhov tshwm sim ntawm random pathological mob uas ua rau cov ntshav qab zib tsis txaus,
- lwm hom insulin tsis haum.
Tab sis txawm hais tias muaj kev taw qhia rau kev noj cov tshuaj no, tus kws kho mob yuav tsum kuaj xyuas tus neeg mob thiab paub tseeb tias tsis muaj kev sib txuam thiab kev tsim nyog ntawm kev kho mob.
Cov lus qhia rau kev siv
Txhawm rau kom tsis txhob ua rau pom qhov tsis zoo los ntawm kev siv Lizpro insulin, koj yuav tsum ua raws nraim li cov lus qhia rau cov tshuaj no.
Qhov ntau npaum ntawm cov tshuaj nyob ntawm ntau cov nta. Qhov no cuam tshuam rau tus neeg mob lub hnub nyoog, daim ntawv ntawm tus kab mob thiab nws qhov mob hnyav, cov kab mob sib kis, thiab lwm yam Yog li ntawd, kev txiav txim qhov koob tshuaj yog qhov ua haujlwm ntawm tus kws kho mob koom.
Tab sis tus kws kho mob tshwj xeeb yuav yuam kev, yog li cov chav kawm ntawm kev kho mob yuav tsum tau saib xyuas tas li los soj ntsuam cov ntshav qab zib thiab kho cov txheej txheem kev kho mob. Tus neeg mob yuav tsum tau saib xyuas nws txoj kev noj qab haus huv zoo thiab qhia tus kws kho mob txog txhua yam kev tsis zoo ntawm lub cev mus rau yeeb tshuaj.
Tsim cov ntawv qhia chaw nyob li cas. Tab sis tsis zoo li feem ntau cov tshuaj zoo sib xws, kev txhaj tshuaj intramuscular tseem raug tso cai, ntxiv rau kev qhia cov tshuaj insulin rau hauv txoj hlab ntshav. Kev txhaj tshuaj rau hauv plab yuav tsum tau ua nrog kev koom tes ntawm tus kws kho mob.
Cov chaw zoo tshaj plaws rau kev txhaj tshuaj subcutaneous yog thaj chaw hauv ceg, lub xub pwg, lub pob tw, lub hauv pliaj xub thawj. Kev qhia ntawm cov tshuaj mus rau tib thaj chaw tsis raug tso cai, vim qhov no ua rau lipodystrophy. Yuav tsum muaj kev txav mus los hauv thaj chaw uas tau xaiv tseg.
Kev txhaj tshuaj yuav tsum tau ua nyob rau hauv ib lub sijhawm ntawm ib hnub. Qhov no yuav ua rau lub cev hloov kho thiab muab cov tshuaj insulin txuas ntxiv.
Nws yog ib qho tseem ceeb xav txog tus neeg mob tej teeb meem kev noj qab haus huv (tsis yog mob ntshav qab zib). Vim qee qhov ntawm lawv, cov nyhuv ntawm cov tshuaj no tuaj yeem ua rau txawv txav lossis qis dua. Hauv qhov no, koj yuav tsum tau rov qab suav lub koob tshuaj. Hauv kev sib txuas nrog lwm cov pathologies, tus kws kho mob feem ntau yuav txwv tsis pub siv cov Humalog.
Tshuaj ntsuab xuv xim video:
Sab nraud thiab contraindications
Nws yog qhov nyuaj kom lav tau qhov tsis muaj kev puas tsuaj los ntawm kev siv tshuaj, tab sis kev pheej hmoo tuaj yeem txo qis, muab cov kev sib kis uas twb muaj lawm. Lizpro tseem muaj lawv, thiab tus kws kho mob, taw nws, yuav tsum ua kom tus neeg mob tsis muaj lawv.
Lub ntsiab contraindications yog:
- kev nkag siab ib leeg rau cov tshuaj ntawm cov tshuaj,
- siab feem ntau rau hypoglycemia,
- muaj cov insulinomas.
Hauv cov xwm txheej zoo li no, Humalog yuav tsum tau hloov nrog lwm cov tshuaj uas muaj cov txiaj ntsig zoo sib xws, tab sis tsis muaj kev phom sij.
Tsis tas li, thaum kho nrog tshuaj insulin, nws yog ib qho tsim nyog yuav tsum coj mus rau hauv tus account qhov tshwm sim tshwm sim. Qhov tshwm sim ntawm qee qhov tsis ua rau muaj kev hem thawj, txij li lawv los ntawm qhov ua tsis tiav ntawm lub cev tsis haum rau cov tshuaj muaj yees.
Tom qab lub sijhawm luv luv, tus neeg tau txais siv mus txhaj, thiab cov kev phiv tshem tawm. Lwm pawg kev mob tshwm sim qhia tias muaj kev nkag tsis tau rau cov khoom no. Cov tsos mob no tsis ploj nrog lub sijhawm, tab sis tsuas yog kev nce qib, tsim kev phom sij tseem ceeb. Yog tias lawv tshwm sim, nws raug nquahu kom thim kev kho mob nrog ib tus neeg sawv cev tiv thaiv insulin.
Feem ntau feem ntau hu ua cov kev mob tshwm sim ntawm lub Humalog, raws li:
Yog tias muaj qhov tshwm sim txawv txawv, tus neeg mob yuav tsum sab laj nrog kws kho mob kom paub tseeb tias tsis muaj kev phom sij.
Cov yam ntxwv ntawm kev cuam tshuam nrog lwm cov tshuaj
Ib qho tseem ceeb heev ntawm kev siv tshuaj yog nws qhov kev sib raug zoo nrog lwm yam tshuaj. Cov kws kho mob feem ntau yuav tsum tau kho ob peb pathologies tib lub sijhawm, vim tias nws yog qhov tsim nyog los ua ke rau kev txais tos ntawm cov tshuaj sib txawv. Nws yog ib qho tsim nyog los teeb tsa txoj kev kho kom cov tshuaj tsis thaiv ntawm txhua qhov kev ua.
Qee zaum muaj qhov xav tau ntawm kev siv tshuaj uas tuaj yeem cuam tshuam qhov kev ua ntawm insulin.
Nws lub zog yog nce ntxiv yog tias, ntxiv rau nws, tus neeg mob siv cov tshuaj hauv qab no:
- Clofibrate
- Ketoconazole,
- MAO inhibitors
- sulfonamides.
Yog tias koj tsis tuaj yeem tsis kam lees txais lawv, koj yuav tsum txo qhov koob tshuaj ntawm nplooj ntawv qhia Humalog.
Cov yeeb tshuaj hauv qab no thiab cov pab pawg ntawm cov neeg sawv cev tuaj yeem ua kom tsis muaj zog ntawm cov tshuaj hauv nqe lus nug:
- estrogens
- nicotine
- tshuaj hormonal rau kev tiv thaiv,
- Glucagon.
Vim tias cov tshuaj no, qhov ua haujlwm ntawm Lizpro yuav txo qis qis, yog li tus kws kho mob yuav tau pom zoo kom nce ntxiv hauv cov tshuaj.
Qee cov tshuaj muaj qee yam tshwm sim tsis tau. Lawv muaj peev xwm nce ntxiv thiab txo qis kev ua haujlwm ntawm cov tshuaj nquag. Cov no suav nrog Octreotide, Pentamidine, Reserpine, beta-blockers.
Cov lus qhia tshwj xeeb
Thaum kho Humalog, qee cov nta nws yuav tsum xav txog.
Ntawm lawv yog hu ua:
Tus kws kho mob yuav tsum qhia tag nrho cov yam ntxwv ntawm tus neeg mob tshuaj. Ua ke nrog tus neeg mob, nws yuav tsum txheeb xyuas txoj kev ua neej thiab kev coj noj coj ua kom nws thiaj li xaiv tau cov kev kho mob uas haum tshaj plaws.
Cov nqi thiab cov qauv ntawm cov tshuaj
Kev kho mob nrog Insulin Lyspro nws kim heev. Tus nqi ntawm ib pob ntawm cov tshuaj zoo li txawv ntawm 1800 txog 200 rubles. Nws yog vim tias tus nqi siab uas tus neeg mob qee zaum thov tus kws kho mob kom hloov cov tshuaj no nrog nws cov tshuaj tiv thaiv nrog cov nqi pheej yig dua.
Muaj ntau ntau cov analogues ntawm cov tshuaj no. Lawv raug nthuav tawm los ntawm cov ntawv sib txawv ntawm cov ntawv tso tawm, yuav txawv hauv lawv muaj pes tsawg leeg.
Ntawm cov neeg tseem ceeb tuaj yeem hais:
Qhov kev xaiv ntawm cov tshuaj los hloov cov hom insulin no yuav tsum tau muab rau tus kws tshwj xeeb.
Qhov tshuaj tiv thaiv tshuaj yog qhov tshuaj hypoglycemic, uas yog ib qho piv ntawm cov insulin luv luv.
Tso tawm daim ntawv thiab muaj pes tsawg leeg
Humalog yog tsim nyob rau hauv daim ntawv ntawm kev daws rau cov leeg (iv) thiab subcutaneous (s / c) kev tswj hwm: tsis muaj xim, pob tshab (hauv cov duab lag luam ntawm 3 ml, hauv qhov hlwv ntawm 5 cartridges, hauv cov duab los qhia ntawm 1 blister, hauv QuickPen syringe cwjmem, rau hauv uas daim cartridges muaj 3 ml ntawm cov tshuaj tov tau muab ntim rau hauv cov thawv ntawv ntawm 5 daim syringe cwjmem.
Cov lus sib xyaw ntawm 1 ml ntawm cov tshuaj:
- cov tshuaj nquag: insulin lispro - 100 ME,
- Lub cev ntu: dej rau kev txhaj tshuaj - txog 1 ml, tov sodium hydroxide 10% thiab (lossis) daws hydrochloric acid 10% - txog pH 7-8, sodium hydrogen phosphate heptahydrate - 0.00188 g, zinc oxide - rau Zn ++ 0.000 0197 g , metacresol - 0.00315 g, glycerin (glycerol) - 0.016 g.
Tsuas tshuaj thiab tswj hwm
Qhov ntau thiab tsawg ntawm cov tshuaj tau txiav txim los ntawm tus kws kho mob ib leeg zuj zus, ua rau qhov kev txiav txim siab ntawm cov piam thaj hauv cov ntshav.
Qhov kev daws teeb meem yog txhaj tshuaj iv - yog tias tsim nyog, yog muaj mob ntawm cov kab mob pathologies, ketoacidosis, ntawm kev ua haujlwm thiab tom qab lub sijhawm txiav txim siab, s / c - nyob rau hauv daim ntawv ntawm kev txhaj tshuaj lossis ncua kev hno (dhau ntawm lub taub dej insulin) hauv plab, pob tw, lub duav lossis xub pwg, tsis yog cia cov khoom lag luam nkag rau hauv cov hlab ntshav. Cov chaw txhaj tshuaj hloov pauv txhua zaus, yog li thaj chaw tsis raug siv ntau tshaj 1 zaug hauv ib hlis. Tom qab tswj hwm, qhov chaw txhaj tshuaj tsis tuaj yeem raug muab tua pov tseg.
Hauv txhua kis, hom kev tswj hwm tus kheej tau teeb tsa tus kheej. Cov lus qhia yog nqa tawm sai ua ntej noj mov, tab sis kev siv cov tshuaj raug tso cai sai tom qab noj mov.
Npaj rau kev tswj hwm tshuaj
Ua ntej siv, txoj kev daws teeb meem tau soj ntsuam rau cov teeb meem, kev ua kom muaj kev phom sij, staining thiab tuab.Tsuas yog siv cov xim tsis muaj xim thiab meej nyob rau hauv chav tsev.
Ua ntej kev txhaj tshuaj, ntxuav koj ob txhais tes kom huv, xaiv thiab so qhov chaw rau kev txhaj tshuaj. Tom ntej no, lub hau raug tshem tawm ntawm rab koob, daim tawv nqaij yog rub los yog sau rau hauv daim loj, rab koob tau tso rau hauv nws thiab lub pob yog nias. Tom qab ntawd, rab koob tau raug tshem tawm thiab rau ob peb vib nas this qhov chaw txhaj tshuaj yog ua tib zoo nias nrog paj rwb pas nrig. Los ntawm txoj kev tiv thaiv lub hau ntawm rab koob nws tau muab tso tseg thiab pov tseg.
Ua ntej siv Humalog nyob rau hauv qhov siv cwj mem-tshuaj (lub taub roj), QuickPen yuav tsum nyeem cov lus qhia rau kev siv.
Qhov kev txhaj tshuaj IV yog tau ua raws li kev kuaj mob ib txwm muaj, piv txwv, IV bolus txhaj tshuaj lossis hla ntawm cov tshuab infusion. Kev nquag saib xyuas cov ntshav qabzib yog qhov tseem ceeb.
Qhov kev ruaj khov ntawm txoj kev nqus ntshav nrog kev tsim kho ntawm 0.1-1 IU rau 1 ml ntawm insulin lispro hauv 5% dextrose lossis 0.9% sodium chloride tov rau 2 hnub yog muab thaum khaws cia hauv chav tsev kub.
Rau nqa tawm sc infusions, Disetronic thiab Minimed twj tsim rau cov tshuaj insulin infusions tuaj yeem siv. Nws yog ib qho tseem ceeb uas yuav tsum ua raws li cov khw muag cov lus qhia thiab ua raws cov cai ntawm asepticism thaum sib txuas cov kab ke. Txhua txhua 2 hnub lawv hloov lub kaw lus rau txoj kev lis ntshav. Txoj kev lis ntshav nrog hypoglycemic rov qab nres yog kom txog thaum nws daws tau lawm. Thaum muaj cov ntshav qabzib tsawg nyob hauv cov ntshav, tus neeg mob yuav tsum sab laj nrog kws kho mob los txiav txim siab txo qis lossis tso tseg cov tshuaj insulin.
Kev nce siab ntxiv hauv cov ntshav qabzib hauv lub ntsej muag tuaj yeem pom nrog txoj kev txhaws rau txoj kev lis ntshav lossis lub mis tsis ua haujlwm. Yog tias ib qho kev ua txhaum ntawm cov tshuaj insulin xa mus ua rau xav tias yog vim li cas kev nce ntxiv hauv cov piam thaj, tus neeg mob yuav tsum ua raws li cov lus qhia ntawm lub chaw tsim khoom thiab qhia tus kws kho mob (yog tias tsim nyog).
Humalog thaum siv lub twj tso kua mis tsis tuaj yeem tov nrog lwm cov insulins.
QuickPen insulin cwj mem muaj 3 ml ntawm tshuaj nrog ib qho haujlwm ntawm 100 IU hauv 1 ml. 1-60 chav tsev ntawm insulin tuaj yeem muab rau ib qho kev txhaj tshuaj. Cov koob tshuaj tuaj yeem tsim nrog qhov tseeb ntawm ib chav. Yog tias ntau cov koog tau tsim tsa, cov koob tshuaj tuaj yeem hloov kho uas tsis muaj qhov poob ntawm insulin.
Lub koob txhaj tshuaj tsuas yog siv los ntawm ib tus neeg mob xwb, cov koob tshiab yuav tsum tau siv rau txhua qhov kev txhaj tshuaj. Tsis txhob siv cov txhaj tshuaj yog tias ib qho ntawm nws feem raug piam lossis tawg. Tus neeg mob yuav tsum nqa lub tshuab nqus dej tas li yog poob lossis puas.
Cov neeg mob uas tsis pom kev tsis pom kev lossis tsis pom kev zoo tsis pom zoo kom siv cov koob tshuaj tsis tas yuav tsum tau txais kev pab zoo los ntawm cov neeg pom kom tau kawm siv nws.
Ua ntej txhua txoj kev txhaj tshuaj, nws yog ib qho tseem ceeb kom paub meej tias lub hnub tas sij hawm uas tau qhia ntawm daim ntawv lo tsis tau tas sij hawm thiab tias hom insulin tseeb muaj nyob hauv lub koob. Hauv qhov no, nws tsis pom zoo kom tshem daim ntawv lo ntawm nws.
Cov xim ntawm cov xim khawm ceev ntawm QuickPen syringe cwj mem yog grey, nws phim cov xim ntawm cov kab txaij rau ntawm nws daim ntawv lo thiab cov tshuaj insulin siv.
Ua ntej siv cov hno, koj yuav tsum xyuas kom tseeb tias rab koob tau txuas ntawm nws. Tom qab siv, rab koob raug tshem tawm thiab pov tseg. Cov xaum xaum yuav tsis khaws cia nrog rab koob txuas rau nws, vim qhov no yuav ua rau huab cua npuas los ua rau hauv lub thawv tshuaj.
Thaum sau ntawv yuav ib koob tshuaj dhau ntawm 60 units, ob qhov kev txhaj tshuaj.
Txhawm rau kuaj cov tshuaj insulin hauv daim cartridge, koj yuav tsum tau taw lub taub hau nrog lub taub ntawm rab koob nce thiab pom tus naj npawb ntawm cov seem ntawm cov tshuaj insulin rau ntawm cov nplai ntawm lub pob tshab yas dhos. Qhov ntsuas no tsis yog siv los teeb lub koob tshuaj.
Txhawm rau kom tshem lub hau ntawm lub injector, koj yuav tsum rub nws. Yog tias muaj kev nyuaj siab tshwm sim, ua tib zoo tig lub hau moos ntawm moos thiab counterclockwise, thiab tom qab ntawd rub nws.
Txhua lub sijhawm ua ntej txhaj tshuaj, lawv tshawb xyuas cov tshuaj insulin kom tsawg, vim tias tsis muaj nws koj tuaj yeem tau txais insulin ntau dhau lossis muaj ntau dhau. Txhawm rau tshuaj xyuas, tshem tawm lub hau sab nraud thiab sab hauv ntawm rab koob, los ntawm tig lub pob koob tshuaj, 2 chav nyob yog teeb tsa, lub taub tso ntshav tau ncaj qha mus sab hauv thiab khob qhov rooj ntawm lub laub kom cov huab cua txhua qhov sau tuaj sab saud. Tom qab ntawd nias lub pob koob tshuaj kom txog thaum nws nres thiab tus lej 0 tshwm nyob rau hauv lub qhov ntsuas qhov ntsuas tshuaj. Tuav lub khawm nyob rau hauv txoj haujlwm recessed, maj mam suav mus rau 5, lub sijhawm no lub pob tshuaj insulin yuav tsum tshwm sim thaum kawg ntawm rab koob. Yog hais tias qhov ua kom yuam kev ntawm insulin tsis tshwm sim, lub koob tau hloov nrog lub tshiab thiab rov qab xeem yog nqa tawm.
Kev tswj hwm tshuaj
- tshem lub hau ntawm cwj mem syringe
- nrog ib qho qhwv ntaws nrog dej cawv, so lub roj hmab disc ntawm qhov kawg ntawm lub cartridge,
- muab rab koob tso rau hauv lub hau ncaj ncaj rau ntawm lub axis ntawm lub taub hau thiab ntsuas hau kom txog thaum nws txuas kiag li,
- los ntawm kev hloov cov koob tshuaj khawm, qhov yuav tsum tau muaj ntawm cov tau teeb tsa,
- tshem lub hau ntawm rab koob thiab ntxig rau hauv qab daim tawv nqaij,
- nrog koj tus ntiv tes xoo, nias lub khawm koob tshuaj kom txog thaum nws nres kiag li. Txhawm rau nkag mus rau qhov tshuaj tag nrho, tuav lub pob thiab maj mam suav rau 5,
- lub koob raug tshem tawm hauv qab ntawm daim tawv nqaij,
- xyuas qhov ntsuas qhov koob tshuaj - yog tias nws muaj tus lej 0 rau nws, cov koob tshuaj tau sau tiav lawm,
- ua tib zoo muab lub hau ntim rau ntawm rab koob thiab muab nws rho tawm ntawm cov koob, mam li muab pov tseg.
- muab lub hau kaw rau ntawm tus cwj mem xaum qhuav.
Yog tias tus neeg mob xav tias nws tau siv tag nrho cov tshuaj, tsis tas yuav rov qab noj dua.
Yeeb tshuaj sib cuam tshuam
Cov nyhuv ntawm cov tshuaj / cov tshuaj ntawm lyspro insulin hauv kev kho ua ke:
- phenothiazine derivatives, nicotinic acid, lithium carbonate, isoniazid, diazoxide, chlorprotixene, thiazide diuretics, tricyclic antidepressants, beta-2-adrenergic agonists (terbutaline, salbutamol, ritodrin, thiab lwm yam), danazole, thyroid-muaj cov thyroid hormones: qhov heev ntawm nws cov hypoglycemic nyhuv,
- angiotensin II receptor antagonists, octreotide, angiotensin-converting enzyme inhibitors (enapril, captopril), qee cov tshuaj tiv thaiv kab mob (monoamine oxidase inhibitors), tshuaj tua kab mob sulfanilamide, salicylates (acetylsalicylic acid, thiab lwm yam, tshuaj phenolic, tetragenurolinogens, tshuaj tiv thaiv hypoglycrogen ethanol thiab ethanol-muaj cov tshuaj, beta-blockers: nce qhov hnyav ntawm nws cov nyhuv hypoglycemic.
Lyspro insulin tsis xyaw nrog tsiaj insulin.
Ua ntej noj lwm yam tshuaj, nws yog ib qho tseem ceeb kom sab laj nrog kws kho mob. Raws li nws qhov kev pom zoo, cov tshuaj no tuaj yeem siv ua ke nrog cov kua dej hauv tib neeg ntev ntev los yog nrog cov ncauj lus ntawm sulfonylureas.
Cov qauv ntawm Humalog yog Iletin I li niaj zaus, Iletin II tsis tu ncua, Nruab Nrab SPP, Nruab Nrab HM, Farmasulin.
Cov Cai Siv Tshuaj So
Tso tawm los ntawm kev kho mob.
Pom qhov yuam kev hauv cov ntawv nyeem? Xaiv nws thiab nias Ctrl + Enter.
Dua li ntawm qhov tseeb hais tias cov kws tshawb fawb tswj tau kom rov ua tiav cov tshuaj insulin molecule, uas tsim tawm hauv tib neeg lub cev, qhov kev ua ntawm cov tshuaj hormones tseem ua rau qeeb qeeb vim lub sijhawm xav kom nqus mus rau hauv cov ntshav. Thawj cov tshuaj ntawm kev ua kom zoo dua yog cov tshuaj insulin Humalog. Nws pib ua haujlwm tau ntev lawm 15 feeb tom qab txhaj tshuaj, yog li ntawd cov suab thaj los ntawm cov ntshav pauv mus rau cov ntaub so ntswg hauv lub sijhawm, thiab txawm tias lub sijhawm luv luv hyperglycemia tsis tshwm sim.
Nws yog ib qho tseem ceeb kom paub! Ib yam tshiab tawm tswv yim los ntawm endocrinologist rau Saib Xyuas Ntshav Qab Zib Ntxiv! Nws tsuas yog tsim nyog txhua hnub.
Piv nrog cov neeg tsim insulins yav dhau los, Humalog qhia tau zoo dua: hauv cov neeg mob, txhua hnub hloov pauv hauv qab zib yog 22%, glycemic qhov ntsuas tau zoo, tshwj xeeb tshaj yog yav tav su, thiab qhov muaj feem yuav ua rau muaj ntshav siab qeeb tsawg dua.Vim tias qhov nrawm nrawm, tab sis qhov kev txiav txim ruaj khov, cov kua dej no yog siv rau hauv cov ntshav qab zib.
Cov qauv kev txhaj tshuaj
Lub humalogue yog pricked ua ntej txhua pluas noj, tsawg kawg peb zaug hauv ib hnub Cov. Nyob rau hauv cov ntaub ntawv ntawm cov piam thaj siab, kho cov menyuam hlob nyob nruab nrab ntawm kev txhaj tshuaj tseem ceeb tau tso cai. Cov lus qhia rau kev siv pom zoo xam xyuas qhov xav tau ntawm cov tshuaj insulin raws li carbohydrates npaj rau pluas noj tom ntej. Txog 15 feeb yuav tsum dhau los ntawm kev txhaj tshuaj mus rau cov zaub mov.
Raws li kev txheeb xyuas, lub sijhawm no feem ntau tsawg dua, tshwj xeeb yog thaum tav su, thaum cov tshuaj tiv thaiv insulin tsawg dua. Qhov nqus tus nqi yog nruj me ntsis rau ib tus neeg, nws tuaj yeem raug suav siv rov ua ntsuas ntsuas cov ntshav qab zib sai sai tom qab txhaj. Yog tias cov ntshav qab zib ua rau pom qhov cuam tshuam sai dua li cov lus qhia, lub sijhawm ua ntej noj mov yuav tsum raug txo kom tsawg.
Humalog yog ib qho tshuaj sai tshaj plaws, yog li nws yooj yim siv nws ua kev pabcuam xwm txheej ceev rau tus mob ntshav qab zib yog tias tus neeg mob nyob rau qhov txaus ntshai.
Lub sijhawm ua haujlwm (luv lossis ntev)
Lub ncov ntawm ultrashort insulin yog pom 60 feeb tom qab nws tswj hwm. Lub sijhawm ua haujlwm nyob ntawm lub koob tshuaj; qhov loj dua nws yog, ntev li ntawm cov suab thaj txo qis dua yog nyob hauv nruab nrab - kwv yees li 4 teev.
Neej Neeg tshaj 25
Txhawm rau kom ntsuas qhov tseeb ntawm qhov tshwm sim ntawm Humalog, qabzib yuav tsum tau ntsuas tom qab lub sijhawm no, feem ntau qhov no ua tiav ua ntej noj mov tom ntej. Kev ntsuas ua ntej yog xav tau yog xav tias tsam lub qog ntshav qab zib tsawg.
Tus kws kho mob ntawm Kev Tshawb Fawb Kev Kho Mob, Lub Taub Hau ntawm lub koom haum ntawm Diabetology - Tatyana Yakovleva
Kuv tau kawm mob ntshav qab zib tau ntau xyoo. Nws yog txaus ntshai thaum muaj coob tus neeg tuag, thiab haj yam ua rau neeg xiam vim ntshav qab zib.
Kuv maj nrawm los qhia txoj xov zoo - Endocrinological qhov chaw tshawb fawb ntawm Lavxias Academy ntawm Medical Science tau tswj hwm los tsim cov tshuaj uas kho cov ntshav qab zib mellitus kom zoo. Thaum lub sijhawm, cov hauj lwm zoo ntawm cov tshuaj no tau nce mus txog 98%.
Lwm qhov xov xwm zoo: Ministry of Health tau ua ib qho kev saws me nyuam uas them rau cov nqi tshuaj ntau heev. Hauv Lavxias, neeg mob ntshav qab zib kom txog lub Peb Hlis 2 tuaj yeem tau txais nws - Tsuas yog 147 rubles!
Lub sijhawm luv luv ntawm lub Humalog tsis yog qhov ua tsis zoo, tab sis qhov zoo ntawm cov tshuaj. Ua tsaug rau nws, cov neeg mob ntshav qab zib mellitus tsis tshua muaj kev tiv thaiv qog ntshav qab zib, tshwj xeeb tshaj yog thaum tsaus ntuj.
Neej Neeg Sib
Ntxiv rau qhov Humalog, lub tuam txhab kev lag luam kws tsim tshuaj Lilly France tsim cov Humalog Mix. Nws yog kev sib xyaw ntawm lyspro insulin thiab protamine sulfate. Ua tsaug rau qhov kev sib txuam no, lub sijhawm pib ntawm cov tshuaj hormone tseem zoo li, thiab lub sijhawm ua haujlwm tau nce ntxiv.
Humalog Mix yog muaj nyob rau hauv 2 ntau qhov:
Qhov zoo dua ntawm cov tshuaj no yog cov tshuaj txhaj yooj yim dua. Them cov ntshav qab zib mellitus thaum lawv siv yog qhov phem dua li nrog kev kho mob ntxiv ntawm kev kho mob insulin thiab kev siv Humalog li ib txwm, yog li ntawd, rau cov me nyuam Humalog Mix tsis siv .
Qhov tshuaj insulin no tau sau tseg:
- Cov neeg mob ntshav qab zib uas tsis tuaj yeem xam tus kheej ntawm koob tshuaj lossis ua ib qho kev txhaj tshuaj, piv txwv, vim tsis pom kev tsis zoo, tuag tes tuag taw lossis tshee.
- Cov neeg mob mob hlwb.
- Cov neeg laus uas muaj ntau yam mob ntshav qab zib thiab kev paub tsis zoo txog kev kho yog tias lawv tsis kam kawm.
- Tus neeg mob ntshav qab zib nrog hom 2 yog tias nws tus kheej ua cov tshuaj hormones tseem tab tom ua.
Kev kho mob ntshav qab zib nrog Humalog Mix yuav tsum noj zaub mov kom nruj, yuav tsum noj khoom txom ncauj thaum noj mov. Nws raug tso cai noj 3 XE rau noj tshais, txog 4 XE rau noj su thiab noj hmo, txog 2 XE rau noj hmo, thiab 4 XE ua ntej yuav mus pw.
Cov Kev Tshaj Tawm ntawm Humalog
Lyspro insulin raws li cov tshuaj nquag muaj tsuas yog nyob hauv thawj phau ntawv teev npe. Cov tshuaj uas ze ze yog (raws li aspart) thiab (glulisin). Cov cuab yeej no tseem yog ultra-luv, yog li nws tsis muaj teeb meem twg uas yuav tsum xaiv. Txhua tus tau txais txiaj ntsig zoo thiab muab cov suab thaj txo ntau.Raws li txoj cai, kev nyiam yog muab rau cov tshuaj, uas tuaj yeem muab pub dawb hauv chaw kho mob.
Qhov kev hloov pauv ntawm Humalog mus rau nws txoj kab ke paum yuav tau tsim nyog muaj kev fab ua txhaum. Yog tias tus mob ntshav qab zib ua raws li cov zaub mov uas tsis muaj carb ntau, lossis feem ntau muaj ntshav qab zib hauv lub cev, nws yog qhov muaj kuab siv tib neeg ntau dua li siv cov tshuaj insulin.
Nco ntsoov kawm! Koj puas xav tias kev tswj hwm kev noj qab haus huv ntawm cov tshuaj thiab cov kua dej yog ib txoj kev los tswj cov piam thaj kom tswj? Tsis muaj tseeb! Koj tuaj yeem soj ntsuam qhov no koj tus kheej los ntawm kev pib siv nws.
DNA recombinant tib neeg cov tshuaj insulin.
Npaj: HUMALOG®
Cov tshuaj nquag ntawm cov tshuaj: tshuaj insulin lyspro
ATX Encoding: A10AB04
KFG: Ua yeeb yam rau neeg lub cev tsis txaus siab
Npe sau npe: P No. 015490/01
Hnub sau npe: 02.02.04
Tswv reg reg. acc .: LAGY FRANCE S.A.S.
Kev daws rau kev txhaj tshuaj yog pob tshab, tsis muaj kob.
1 ml
tshuaj insulin lispro *
100 IU
Cov kev zam: glycerol, zinc oxide, sodium hydrogen phosphate, m-cresol, dej d / thiab, hydrochloric acid tov ntawm 10% thiab sodium hydroxide tov ntawm 10% (los tsim kom muaj qib pH uas yuav tsum tau).
3 ml - cartridges (5) - hlwv (1) - pob khoom los ntawm cardboard.
* Lub npe tsis yog thoob ntiaj teb lub npe pom zoo los ntawm WHO. Hauv Lavxias Lavxias, kev sau tus ntawv lub npe thoob ntiaj teb yog insulin lispro.
Cov lus piav qhia ntawm cov tshuaj yog ua raws cov lus qhia raug pom zoo rau kev siv.
Humulin insulin hauv qhov xaum qhuav
Humalog yog tshuaj uas yog ib qho tshuaj noj ntawm lub cev insulin tsim los ntawm tib neeg lub cev. DNA yog hloov kho tus neeg sawv cev. Qhov peculiarity yog tias Humalog hloov cov lus sib xyaw ntawm cov amino acid hauv cov kab txuas insulin. Cov tshuaj tswj cov metabolism hauv cov piam thaj hauv lub cev. Nws yog hais txog cov tshuaj uas muaj cov teebmeem anabolic.
Kev txhaj tshuaj ntawm cov tshuaj pab txhawm rau txhawm rau ntxiv glycerol, fatty acids thiab glocogen hauv lub cev. Pab ua kom muaj protein ntau sib txuas. Cov txheej txheem kev noj cov amino acids yog nrawm, uas ua rau kom txo qis ketogenesis, glucogenogenesis, lipolysis, glycogenolysis, protein catabolism. Cov tshuaj no muaj cov nyhuv luv luv.
Lub ntsiab lus ntawm Humalog yog insulin lispro. Kuj, qhov muaj pes tsawg leeg yog ntxiv nrog kev ua si ntawm kev ua hauv cheeb tsam. Tseem muaj qhov sib txawv ntawm cov tshuaj - Humalogmix 25, 50 thiab 100. Nws lub ntsiab sib txawv yog muaj Hagedorn nyob rau hauv nruab nrab provitamin, uas ua rau qeeb qeeb ntawm cov tshuaj insulin.
Tus xov tooj 25, 50 thiab 100 qhia tus naj npawb ntawm NPH hauv tshuaj. Ntau Humalogmix muaj qhov ua kom nruab nrab tsis txaus ntseeg Hagedorn, ntau dua cov tshuaj noj yuav ua. Yog li, koj tuaj yeem txo qhov xav tau ntau los ntawm kev txhaj tshuaj, tsim rau ib hnub. Kev siv cov tshuaj no pab tswj kev kho mob kom qab zib thiab ua lub neej yooj yim.
Zoo li txhua yam tshuaj Humalogmix 25, 50 thiab 100 muaj qhov tsis zoo.
Cov tshuaj tsis tso cai rau kev tswj hwm kom ua tiav cov ntshav qab zib.
Tseem muaj kev paub txog kev ua xua ntawm kev phiv tshuaj thiab lwm cov kev mob tshwm sim. Cov kws kho mob feem ntau sau ntawv Humalog insulin hauv nws daim ntawv ntshiab dua li kev sib tov, vim ntau npaum li cas ntawm NPH 25, 50 thiab 100 tuaj yeem ua rau cov ntshav qab zib tsis txaus, feem ntau lawv dhau los ua mob ntev. Nws yog qhov siv tau los siv ntau hom thiab ntau txoj kev kho mob rau cov neeg laus laus uas nyob nrog ntshav qab zib.
Feem ntau, cov kev xaiv ntawm cov tshuaj no yog vim muaj lub sijhawm luv luv ntawm cov neeg mob thiab kev txhim kho ntawm cov laus dementia. Rau cov seem ntawm cov neeg mob, Humalog hauv nws daim ntawv dawb huv yog kev pom zoo.
Cov tshuaj yog muaj raws li kev ncua rau kev txhaj tshuaj hauv qab daim tawv. Cov tshuaj nquag yog insulin lispro 100 IU.
Cov tshuaj ntxiv hauv qhov muaj pes tsawg leeg:
- 1.76 mg metacresol,
- 0.80 mg ntawm phenol kua,
- 16 mg ntawm glycerol (glycerol),
- 0.28 mg provitamin sulfate,
- 3.78 mg ntawm sodium hydrogen phosphate,
- 25 mcg ntawm zinc oxide,
- 10% hydrochloric acid daws,
- Txog li 1 ml ntawm dej rau kev txhaj tshuaj.
Cov tshuaj yog xim dawb nyob rau hauv cov xim, muaj peev xwm ua kom exfoliating. Qhov tshwm sim yog lub caij ntuj nag dawb thiab cov kua ntshiab ntshiab uas ntxiv rau hauv qhov nag lossis daus. Rau kev txhaj tshuaj, nws yog ib qhov tsim nyog los sib tov cov kua tsim nrog kev ua kom yoog los ntawm maj mam tuav cov ampoules. Humalogue yog hais txog kev sib txuas ntawm cov analogues ntawm ntuj insulin nrog ib nrab thiab luv ntawm kev ua.
Sib tov 50 quicpen yog kev sib xyaw ntawm qhov zoo sib xws rau kev ua haujlwm sai insulin (insulin solution lispro 50%) thiab qhov nruab nrab (provitamin raug rho tawm insulin lispro 50%).
Qhov kev tsom xam ntawm cov tshuaj no yog tswj cov kev zom zaub mov kom muaj suab thaj hauv lub cev. Cov ncauj lus anabolic thiab tiv thaiv catabolic hauv ntau lub hlwb ntawm lub cev puav leej raug sau tseg.
Lizpro yog cov tshuaj insulin, uas zoo sib xws rau cov tshuaj hormones tsim hauv tib neeg lub cev, txawm hais tias tag nrho cov ntshav qab zib cov ntshav tshwm sim sai dua, tab sis cov nyhuv kav ntev dua. Kev nqus ntawm cov ntshav thiab qhov pib ntawm qhov kev nqis tes ua ncaj qha nyob ntawm ntau yam:
- qhov chaw txhaj tshuaj (nkag mus rau hauv plab, hips, pob tw),
- ntau npaum (yuav tsum tau siv tshuaj insulin),
- cov ntshav ncig ua haujlwm
- lub cev kub ntawm tus neeg mob
- kev tawm dag zog lub cev.
Ua rau kev txhaj tshuaj, cov nyhuv ntawm cov tshuaj pib hauv 15 feeb tom ntej. Feem ntau, qhov kev ncua yog txhaj rau hauv qab daim tawv nqaij ob peb feeb ua ntej noj mov, uas yuav pab kom tsis txhob muaj cov kua nplaum duav ntxiv. Rau kev sib piv, qhov ua tau zoo ntawm lyspro insulin tuaj yeem sib piv los ntawm nws cov kev ua nrog tib neeg cov insulin - isophan, uas nws qhov kev txiav txim siab tuaj yeem ntev txog 15 teev.
Raws li kev tsim nyog rau kev siv tshuaj xws li Humalogmix 25, 50 thiab 100, cov lus qhia rau kev siv yuav tsim nyog. Nws yuav tsum tau nco qab tias cov tshuaj siv rau hauv ntshav qab zib mellitus rau kev kho mob ntawm cov neeg mob ntawm cov hnub nyoog sib txawv, rau lub neej ib txwm ntawm uas cov tshuaj insulin xav tau txhua hnub. Qhov yuav tsum tau txhaj ntau zaus thiab ntau zaus ntawm kev tswj hwm tsuas yog txiav txim los ntawm kws kho mob.
Nws muaj 3 txoj kev txhaj tshuaj:
Txog kev kho mob ntshav qab zib tau zoo hauv tsev, cov kws tshaj lij qhia DiaLife Cov. Nov yog qhov cuab yeej tshwj xeeb:
- Normalizes ntshav qabzib
- Regulates pancreatic muaj nuj nqi
- Tshem tawm puffiness, tswj hwm dej metabolism
- Kho txhim qhov muag pom
- Haum rau cov laus thiab menyuam yaus.
- Muaj tsis muaj contraindications
Peb muab cov luv nqi rau cov nyeem ntawm peb lub xaib!
Yuav ntawm lub vev xaib raug cai
- hauv qab daim tawv nqaij
- tso leeg ntshav
- intramuscularly.
Tsuas yog cov kws tshwj xeeb tuaj yeem muab cov tshuaj rau hauv cov chaw muaj mob. Qhov no yog vim qhov tseeb tias kev tswj hwm tus kheej ntawm cov tshuaj hauv txoj hauv kev no coj qee yam kev pheej hmoo. Cov insulin cartridge yog tsim los rov qab nqus cov ntawv xaum rau cov neeg mob ntshav qab zib. Cov lus qhia hauv txoj hauv kev no yog nqa tawm tshwj xeeb hauv qab daim tawv nqaij.
Qhov qhia tshuaj Chiv no yog nkag mus rau hauv lub cev hauv qhov siab ntev li 15 feeb. ua ntej noj mov, los sis ncaj qha li ib feeb tom qab noj mov. Qhov ntau zaus ntawm kev txhaj tshuaj tuaj yeem sib txawv ntawm 4 txog 6 zaug hauv ib hnub. Thaum cov neeg mob noj tshuaj insulin ntev, kev txhaj tshuaj txo tsawg dua 3 zaug hauv ib hnub. Nws yog txwv tsis pub tshaj qhov ntau tshaj qhov tau them los ntawm kws kho mob yog tias tsis muaj qhov mob xav tau sai.
Nyob rau hauv parallel nrog cov tshuaj no, lwm yam analogues ntawm lub cev ntuj kuj raug tso cai. Nws yog tswj hwm los ntawm kev sib xyaw ob qho khoom lag luam rau hauv ib tus cwj mem syringe, uas ua rau kev txhaj tshuaj yooj yim dua, yooj yim thiab nyab xeeb. Ua ntej kev txhaj tshuaj yuav pib, daim cartridge nrog cov tshuaj yuav tsum tov kom txog thaum tus, dov hauv xib teg ntawm koj txhais tes. Koj tsis tuaj yeem co thawv nrog cov tshuaj kom ntau, vim tias muaj kev pheej hmoo ntawm kev tsim npaus, qhov kev qhia ntawm qhov tsis tsim nyog.
Cov kev qhia kwv yees cov nram qab no algorithm ntawm kev nqis tes, yuav ua li cas siv ntawm Humalogmix kom raug:
- Ua ntej tshaj plaws, koj yuav tsum ntxuav koj txhais tes kom zoo, ib txwm siv xab npum.
- Txheeb xyuas qhov chaw txhaj tshuaj, txhuam nws nrog daim ntawv caw cawv.
- Nruab lub taub ntim hauv cov ntawv txhaj tshuaj, co maj mam mus rau ntau qhov kev qhia ntau zaus. Yog li cov tshuaj yeeb yaj kiab yuav nce tus yam ntxwv tsis sib thooj, ua pob tshab thiab tsis muaj xim. Tsuas siv cov roj cartridges nrog kua txheem tsis muaj huab seem.
- Xaiv cov koob txhaj tshuaj rau kev tswj hwm.
- Qhib lub koob txhaj los ntawm kev tshem lub hau.
- Kho cov tawv nqaij.
- Ntxig rau tag nrho rab koob hauv qab daim tawv nqaij. Ua kom tiav qhov taw tes no, koj yuav tsum ua tib zoo kom tsis txhob nkag mus rau hauv cov hlab.
- Tam sim no koj yuav tsum nias lub khawm, tuav cia.
- Tos rau lub teeb liab kom ua tiav kev tswj hwm tshuaj los ua suab, suav 10 vib nas this. thiab rub tawm cov phwj hauv. Ua kom ntseeg tau tias cov koob xaiv tau raug tswj hwm ua tiav.
- Tso cov ntawv caw cawv rau ntawm qhov chaw txhaj tshuaj. Nyob hauv ib qho xwm txheej twg yuav tsum koj tsis txhob nyem, txhuam lossis zaws ntawm qhov chaw txhaj tshuaj.
- Kaw lub koob nrog lub hau tiv thaiv.
Thaum siv cov tshuaj, koj yuav tsum coj mus rau hauv tus account tias cov tshuaj hauv lub thawv ntawv yuav tsum muab sov so hauv txhais tes ua ntej siv chav. Taw qhia hauv qab daim tawv nqaij ntawm yeeb tshuaj nrog rab koob xaum xaum yog nqa ntawm caj pas, xub pwg, plab lossis pob tw. Nws raug nquahu kom tsis txhob txhaj rau tib qho chaw. Qhov chaw ntawm lub cev mus rau hauv cov insulin txhaj tshuaj txhua hli yuav tsum pauv hloov. Siv Humalog tsuas yog tom qab ntsuas ntsuas cov piam thaj kom tsis txhob muaj kev txhim kho ntawm cov teeb meem.
Txhawm rau kom tshem tawm cov ntshav qab zib hauv kev kho mob, nws yog kev coj los siv insulin analogues.
Sij hawm dhau mus, cov tshuaj zoo li no tau dhau los ntawm cov kws kho mob thiab lawv cov neeg mob.
Tus qauv zoo li tuaj yeem piav qhia:
- qhov siab tsim nyog ntawm cov tshuaj insulin hauv kev tsim khoom,
- kev ruaj ntseg zoo tshaj plaws profile,
- yooj yim ntawm kev siv
- lub peev xwm los synchronize kev txhaj tshuaj nrog nws tus kheej zais cia ntawm cov tshuaj hormones.
Tom qab ib ntus, cov neeg mob uas muaj ntshav qab zib hom 2 mellitus raug yuam kom hloov los ntawm cov ntshav qab zib-txo cov ntsiav tshuaj mus rau kev txhaj tshuaj ntawm cov tshuaj insulin. Yog li no, lo lus nug ntawm kev xaiv cov tshuaj noj kom zoo rau lawv yog qhov tseem ceeb.
Pheej yig analogues Humalog
# | Npe | Nqe hauv Lavxias | Nqe hauv Ukraine |
---|---|---|---|
1 | tib neeg cov insulin | 31 RUB | -- |
2 | glulisin Analogue hauv kev taw qhia thiab txoj kev siv | 38 RUB | 2250 UAH |
3 | tib neeg cov insulin Analogue hauv kev taw qhia thiab txoj kev siv | 39 RUB | 1172 UAH |
4 | insulin aspart Analogue hauv kev taw qhia thiab txoj kev siv | 309 rub | 249 UAH |
5 | Analogue hauv kev taw qhia thiab txoj kev siv | 342 rub | 7 UAH |
Thaum xam xyuas tus nqi pheej yig analogues Humalog tus nqi yam tsawg kawg nkaus uas tau pom hauv daim ntawv teev tus nqi muab los ntawm cov khw muag tshuaj tau raug coj los suav
Cov Khoom Siv Hluav Taws Xob Zoo Li Qub
# | Npe | Nqe hauv Lavxias | Nqe hauv Ukraine |
---|---|---|---|
1 | tib neeg cov insulin Analogue hauv kev taw qhia thiab txoj kev siv | 31 RUB | -- |
2 | tib neeg cov insulin Analogue hauv kev taw qhia thiab txoj kev siv | 39 RUB | 1172 UAH |
3 | glulisin Analogue hauv kev taw qhia thiab txoj kev siv | 38 RUB | 2250 UAH |
4 | insulin aspart Analogue hauv kev taw qhia thiab txoj kev siv | 309 rub | 249 UAH |
5 | Analogue hauv kev taw qhia thiab txoj kev siv | 342 rub | 7 UAH |
Muab daim ntawv teev cov tshuaj analogues raws li kev txheeb cais ntawm cov tshuaj feem ntau thov
Analogs los ntawm qhov taw qhia thiab cov qauv ntawm kev siv
Npe | Nqe hauv Lavxias | Nqe hauv Ukraine |
---|---|---|
342 rub | 7 UAH | |
368 rub | 7 UAH | |
750 rub | 115 UAH | |
352 RUB | -- | |
tib neeg cov insulin | 1000 rub | 7 UAH |
tib neeg cov insulin | -- | -- |
tib neeg cov insulin | 39 RUB | 1172 UAH |
-- | 7 UAH | |
tib neeg cov insulin | -- | 7 UAH |
tib neeg cov insulin | -- | -- |
tib neeg cov insulin | 31 RUB | -- |
tib neeg cov insulin | -- | 7 UAH |
tib neeg cov insulin | -- | 7 UAH |
tshuaj insulin (nqaij npuas) | -- | 80 UAH |
insulin aspart | 309 rub | 249 UAH |
insulin aspart | 801 rub | 1643 UAH |
tshuaj insulin glulisin | -- | 7 UAH |
glulisin | 38 RUB | 2250 UAH |
Sib txawv muaj pes tsawg leeg, tuaj yeem ua ke nyob rau hauv kev taw qhia thiab cov qauv ntawm daim ntawv thov
Npe | Nqe hauv Lavxias | Nqe hauv Ukraine |
---|---|---|
192 RUB | 133 UAH | |
48 rub | -- | |
tib neeg cov insulin | 258 rub | 7 UAH |
350 rub | 7 UAH | |
tib neeg cov insulin | -- | -- |
tib neeg cov insulin | 1040 rub | 7 UAH |
tib neeg cov insulin | -- | 7 UAH |
tib neeg cov insulin | -- | -- |
tib neeg cov insulin | 356 rub | 7 UAH |
tib neeg cov insulin | 870 rub | 7 UAH |
tib neeg cov insulin | 125 rub | -- |
tib neeg cov insulin | -- | 7 UAH |
tib neeg cov tshuaj insulin | -- | 7 UAH |
tshuaj insulin | -- | -- |
tshuaj insulin (nqaij npuas) | -- | 80 UAH |
tib neeg cov insulin | -- | -- |
tib neeg cov insulin | -- | 7 UAH |
tib neeg cov insulin | -- | -- |
tib neeg cov insulin | -- | 7 UAH |
tib neeg cov insulin | -- | 7 UAH |
tib neeg cov insulin | -- | -- |
tib neeg cov insulin | -- | 101 UAH |
tib neeg cov insulin | 235 rub | -- |
tshuaj insulin lispro | 1250 RUB | 7 UAH |
insulin aspart | -- | -- |
tshuaj insulin aspart, insulin degludec | 7340 rub | 2705 UAH |
insulin glargine | 885 rub | 7 UAH |
insulin glargine | 885 rub | 7 UAH |
insulin glargine | 29 RUB | -- |
tshuaj insulin | 2160 RUB | -- |
tshuaj insulin | 1090 RUB | 7 UAH |
tshuaj insulin degludec | 72 RUB | 2 UAH |
Txhawm rau kom sau cov npe ntawm cov kab mob sib txuas pheej yig ntawm cov tshuaj kim, peb siv cov nqi uas muab peb ntau tshaj 10,000 khw muag tshuaj thoob plaws hauv Lavxias. Cov ntaub ntawv teev cov tshuaj thiab lawv cov analogues tau hloov kho tshiab txhua hnub, yog li cov ntaub ntawv muaj nyob hauv peb lub vev xaib yog ib txwm hloov kho raws li niaj hnub no. Yog tias koj tsis tau pom ib qho analogue ntawm kev txaus siab rau koj, thov siv qhov kev tshawb nrhiav saum toj no thiab xaiv cov tshuaj ntawm kev txaus siab rau koj los ntawm cov npe. Ntawm nplooj ntawv ntawm txhua ntawm lawv koj yuav pom tag nrho cov kev xaiv ua tau rau cov qauv ntawm cov tshuaj xav tau, nrog rau tus nqi thiab chaw nyob ntawm cov khw muag tshuaj uas nws muaj.
Kev qhia ua ntu neeg
subcutaneous kev ncua
Kev sib xyaw ntawm lyspro insulin - kev ua yeeb yam sai sai thiab kev tiv thaiv tshuaj tiv thaiv ntawm lyspro insulin - nruab nrab ua yeeb yam insulin. Lyspro insulin yog qhov tso tawm DNA ntawm tib neeg cov tshuaj insulin; nws txawv ntawm nws los ntawm kev rov qab los ntawm proline thiab lysine amino acid seem ntawm txoj haujlwm 28 thiab 29 ntawm cov kab insulin B. Regulates metabolism hauv cov piam thaj, muaj cov teebmeem anabolic. Hauv cov leeg nqaij thiab lwm cov nqaij (muaj qhov tsis suav ntawm lub hlwb) nws ua kom sai ntawm kev hloov pauv ntawm cov piam thaj thiab amino acids mus rau hauv lub cell, txhawb txoj kev tsim cov glycogen los ntawm cov piam thaj hauv lub siab, ua rau gluconeogenesis thiab txhawb kev hloov pauv ntawm cov piam thaj mus rau cov rog. Equimolar rau tib neeg cov tshuaj insulin. Piv nrog tib neeg cov tshuaj insulin, nws muaj qhov tshwm sim ntawm kev pib sai dua, kev pib ua tiav ntawm qhov siab kawg thiab lub sijhawm luv dua ntawm kev ua haujlwm hypoglycemic (txog 5 teev). Kev pib sai ntawm kev nqis tes ua (15 feeb tom qab kev tswj hwm) cuam tshuam nrog kev nqus siab thiab tso cai rau nws ua kom sai li sai tau ua ntej noj mov (15 feeb) - tib neeg cov tshuaj insulin raug tswj hauv 30 feeb. Kev xaiv ntawm qhov chaw txhaj tshuaj thiab lwm yam tuaj yeem cuam tshuam tus nqi ntawm kev nqus thiab pib ntawm nws cov kev ua. Qhov siab tshaj plaws tau pom ntawm 0.5 thiab 2.5 teev, lub sijhawm ua ntawm 3-4 teev.
Hom 1 mob ntshav qab zib mellitus, tshwj xeeb tshaj yog nrog kev tsis nkag siab ntawm lwm cov insulins, postprandial hyperglycemia uas tsis tuaj yeem kho los ntawm lwm cov insulins: mob subcutaneous insulin tsis kam (nrawm hauv zos kev cuam tshuam ntawm insulin). Hom 2 mob ntshav qab zib mellitus - nyob rau hauv kis ntawm tsis kam mus rau qhov ncauj hypoglycemic tshuaj, nyob rau hauv kev ua txhaum ntawm kev nqus ntawm lwm cov tshuaj insulin, thaum lub sijhawm ua haujlwm, cov kabmob sib kis.
Kev ua haujlwm tsis txaus siab, kev ua ntshav qab zib, insulinoma.
Kev tsis haum tshuaj (urticaria, angioedema - ua npaws, ua tsis taus pa, ntshav tsawg), lipodystrophy, ua rau muaj qhov tsis zoo ntawm lub sijhawm (feem ntau hauv cov neeg mob uas tsis tau txais insulin yav dhau los), hypoglycemia, hypoglycemic com. Cov tsos mob: tsaug zog, tawm hws, tawm hws, tawm hws, tsis pom kev, tachycardia, tshee tshee, tshaib plab, ntxhov siab, mob plab nyob rau hauv lub qhov ncauj, pallor ntawm daim tawv nqaij, mob taub hau, tshee tshee, ntuav, tsaug zog, pw tsaug zog, ntshai, ntxhov siab, chim siab, txawv txav, qhov tsis paub tseeb txog kev txav chaw, tsis hnov lus thiab pom lub zeem muag, tsis meej pem, hypoglycemic coma, nriaj.Kev Kho Mob: yog tias tus neeg mob nco qab, nws tau txiav txim siab dextrose qhov ncauj, s / c, i / m lossis iv txhaj tshuaj glucagon lossis iv hypertonic dextrose tov. Nrog rau kev txhim kho lub ntsej muag tsis nco qab, 20-40 ml (txog 100 ml) ntawm 40% dextrose tov yog txhaj iv rau hauv qhov dej kom txog thaum tus neeg mob tawm ntawm lub cev tsis nco qab.
Muab thiab kev coj:
Cov koob tshuaj tau txiav txim siab ib tus zuj zus nyob ntawm theem ntawm glycemia. Kev sib xyaw 25% insulin lispro thiab 75% kev tiv thaiv tshuaj tiv thaiv yuav tsum tau tsuas yog muab s / c, feem ntau 15 feeb ua ntej noj mov. Yog tias tsim nyog, koj tuaj yeem nkag mus nrog kev siv tshuaj insulin kom ntev los yog nrog sulfonylureas rau kev tswj hwm qhov ncauj. Kev txhaj tshuaj yuav tsum tau ua s / c hauv lub xub pwg, lub duav, lub duav lossis lub plab. Qhov chaw txhaj tshuaj yuav tsum tau hloov chaw kom qhov chaw qub siv tsis ntau tshaj 1 zaug hauv ib hlis. Nrog s / c tswj hwm, kev saib xyuas yuav tsum tau ua kom tsis txhob nkag rau cov ntshav ntshav. Hauv cov neeg mob lub raum thiab / lossis daim siab ua haujlwm, cov theem ntawm cov ntshav insulin nce ntxiv, thiab qhov xav tau nws tuaj yeem txo qis, uas yuav tsum tau ceev faj soj ntsuam ntawm qib ntawm glycemia thiab koob tshuaj kho mob ntawm insulin.
Cov kev ntawm cov thawj coj tswj hwm rau daim ntawv ntau npaum siv yuav tsum tau nruj siv. Thaum hloov cov neeg mob los ntawm kev ua yeeb yam sai ntawm cov tsiaj keeb kwm rau insulin lispro, yuav tsum tau txhaj koob tshuaj. Kev hloov chaw ntawm cov neeg mob tau txais cov tshuaj insulin nyob rau hauv ib hnub ntau dua 100 units los ntawm ib hom tshuaj insulin rau lwm tus yog pom zoo kom nqa tawm hauv tsev kho mob. Qhov xav tau ntawm cov tshuaj insulin tuaj yeem nce ntxiv thaum muaj kab mob kis, nrog kev ntxhov siab hauv lub siab, nrog qhov nce ntawm cov khoom noj carbohydrates hauv zaub mov, thaum ntxiv kev noj tshuaj ntxiv nrog hyperglycemic kev ua si (cov thyroid hormones, GCS, qhov ncauj tiv thaiv kab mob, thiazide diuretics). Qhov xav tau ntawm cov tshuaj insulin tuaj yeem txo nrog lub raum thiab / lossis lub siab ua haujlwm, nrog qhov txo qis hauv cov khoom noj hauv cov zaub mov, nrog kev tawm dag zog lub cev, thaum ntxiv kev noj tshuaj nrog hypoglycemic kev ua si (MAO inhibitors, tsis xaiv-beta-blockers, sulfonamides). Kev ntsuam xyuas kev txhim kho hypoglycemia tuaj yeem cuam tshuam cov peev xwm ntawm cov neeg mob koom tes hauv kev khiav tsheb, nrog rau kev saib xyuas cov tshuab thiab tshuab. Cov neeg mob ntshav qab zib tuaj yeem txwv cov ntshav qab zib tsawg uas lawv xav los ntawm kev noj cov piam thaj lossis zaub mov ntau hauv carbohydrates (Nws raug nquahu kom koj ib txwm muaj tsawg kawg 20 g suab thaj nrog koj). Nws yog ib qho tsim nyog yuav tsum tau qhia rau tus kws kho mob uas tau tuaj kawm txog qhov hloov pauv hypoglycemia txhawm rau daws qhov teeb meem ntawm qhov xav tau ntawm kev kho mob kho. Qhov xav tau rau cov tshuaj insulin feem ntau poob qis hauv thawj peb lub hlis thaum cev xeeb tub thiab nce hauv qib thib ob txog rau qib thib peb. Thaum yug menyuam thiab tam sim ntawd tom qab lawv, xav tau cov tshuaj insulin tuaj yeem txo qis.
Txhua yam lus tau hais tawm rau kev qhia tawm thiab tsis yog lub laj thawj ntawm kev kho tus kheej lossis hloov cov tshuaj.
Kev daws rau iv thiab sc coj pob tshab, tsis muaj xim.
Cov muaj tswv yim: glycerol (glycerin) - 16 mg, metacresol - 3.15 mg, zinc oxide (q.s. rau Zn 2+ cov ntsiab lus 0.0197 mcg), sodium hydrogen phosphate heptahydrate - 1.88 mg, hydrochloric acid daws 10% thiab / lossis sodium hydroxide tov 10% - q.s. mus txog pH 7.0-8.0, dej d / i - q.s. txog li 1 ml.
3 ml - cartridges (5) - hlwv (1) - pob khoom los ntawm cardboard.
3 ml - cartridge ua rau QuickPen ™ syringe cwj mem (5) - pob cov duab los qhia.
Cov lus piav qhia txog cov tshuaj yog nyob ntawm cov lus qhia rau kev siv thiab pom zoo los ntawm cov kws tsim khoom.
Cov Tshuaj Pharmacokinetics
Xuas thiab faib khoom
Tom qab cov tswj hwm sc, cov tshuaj insulin lyspro nrawm thiab nce mus txog C max hauv ntshav ntshav tom qab 30-70 feeb. V d ntawm lyspro insulin thiab insulin cov tib neeg zoo ib yam thiab muaj nyob rau ntawm ntau yam 0.26-0.36 l / kg.
Nrog s / c tswj hwm ntawm T 1/2 ntawm cov tshuaj insulin, lispro yog li 1 teev.Hauv cov neeg mob uas lub raum thiab hepatic tsis txaus, tus nqi siab dua ntawm kev nqus ntawm lyspro insulin tseem piv rau cov neeg muaj peev xwm insulin.
- mob ntshav qab zib mellitus hauv cov neeg laus thiab menyuam yaus, yuav tsum tau siv cov tshuaj insulin los pab tswj cov ntshav qabzib kom ntau.
Kev noj tshuaj ntxiv
Tus kws kho mob txiav txim siab muab koob tshuaj ib leeg zuj zus, nyob ntawm qhov xav tau ntawm tus neeg mob. Cov tshuaj Humalog ® tuaj yeem muab noj ua ntej noj mov, yog tias yuav tsum tau ua sai tom qab noj mov.
Qhov ntsuas kub ntawm cov tshuaj tso cai yuav tsum nyob ntawm chav sov.
Humalog ® raug tswj s / c nyob rau hauv daim ntawv ntawm kev txhaj tshuaj lossis hauv daim ntawv ntawm kev txuas ntxiv s / c infusion siv lub twj tso kua mis. Yog tias tsim nyog (ketoacidosis, mob hnyav, lub sijhawm ntawm kev ua haujlwm lossis sijhawm hla sijhawm) Humalog ® tuaj yeem nkag mus rau hauv / hauv.
SC yuav tsum muab rau lub xub pwg, ncej puab, pob tw, lossis plab. Qhov chaw txhaj tshuaj yuav tsum tau hloov chaw kom tib qhov chaw siv tsis ntau tshaj 1 zaug hauv ib hlis. Thaum s / qhia txog cov tshuaj Humalog ®, yuav tsum saib xyuas kom tsis txhob txais cov tshuaj rau hauv cov hlab ntshav. Tom qab txhaj tshuaj, qhov chaw txhaj tshuaj yuav tsum tsis txhob zaws. Tus neeg mob yuav tsum tau kawm siv cov txheej txheem kev txhaj tshuaj kom raug.
Cov kev cai ntawm kev tswj hwm ntawm cov tshuaj Humalog ®
Npaj rau kev qhia
Kev daws tshuaj Humalog ® yuav tsum pob tshab thiab xim tsis muaj xim. Ib qho huab, tuab lossis xim me ntsis ntawm cov tshuaj, lossis yog tias cov khoom tawg tau pom los rau hauv nws, yuav tsum tsis txhob siv.
Thaum txhim kho lub taub ntim hauv cov koob txhaj tshuaj (tus cwj mem-txhaj), txuas lub koob thiab coj kev txhaj tshuaj insulin, nws yog qhov yuav tsum tau ua raws li cov khw muag cov lus qhia uas txuas nrog txhua tus xaum xim.
2. Xaiv lub xaib rau kev txhaj tshuaj.
3. Antiseptic tawv nqaij ntawm qhov chaw txhaj tshuaj.
4. Tshem tawm lub hau ntawm rab koob.
5. Kho cov tawv nqaij los ntawm kev ncab nws lossis los ntawm kev ruaj ntseg ntawm cov quav loj. Ntxig lub koob txhaj tshuaj raws li cov lus qhia siv kev xaum xim.
6. Nias lub pob ntawd.
7. Tshem tawm rab koob thiab maj mam nyem qhov chaw txhaj tshuaj rau ob peb feeb. Tsis txhob txhuam thaj chaw txhaj tshuaj.
8. Kev siv rab koob rab koob, tshem tawm rab koob thiab rhuav tshem nws.
9. Qhov chaw txhaj tshuaj yuav tsum tau hloov chaw kom qhov chaw qub siv tsis ntau tshaj li 1 zaug hauv ib hlis.
Kev tswj hwm ntawm insulin
Kev txhaj tshuaj ntawm cov tshuaj Humalog ® yuav tsum ua raws li kev siv tshuaj txhaj rau txoj kev txhaj tshuaj, piv txwv, txhaj tshuaj bolus tswj hwm lossis siv cov txheej txheem infusion. Hauv qhov no, nws yog ib qho tsim nyog feem ntau los tswj cov qib ntawm cov piam thaj hauv cov ntshav.
Lub tshuab ua ke nrog cov ntsiab lus los ntawm 0.1 IU / ml rau 1.0 IU / ml ntawm insulin lispro hauv 0.9% sodium chloride tov lossis 5% dextrose daws yog ruaj khov nyob rau chav sov li 48 teev.
P / C insulin infusion siv lub twj tso kua mis
Rau Txoj kev lis ntshav ntawm Humalog ®, Minimed thiab Disetronic twj tuaj yeem siv rau insulin infusion. Koj yuav tsum nruj me ntsis ua raws cov lus qhia uas tuaj nrog lub twj tso kua mis. Txoj kev lis ntshav yog hloov pauv txhua 48 teev .Thaum txuas lub infusion system, kev cai aseptic tau pom. Thaum muaj qhov qog ntawm hypoglycemic, Txoj kev lis ntshav yog nres kom txog rau thaum rov zoo. Yog tias pheej rov qab ua lossis txo qis dua cov piam thaj hauv cov ntshav, tom qab ntawd koj yuav tsum qhia koj tus kws kho mob txog qhov no thiab txiav txim siab yuav txo qis lossis tso tseg cov tshuaj insulin. Lub twj tso kua mis tsis ua hauj lwm lossis kev txhaws hauv txoj kev lis ntshav tuaj yeem ua rau nce ntxiv hauv cov piam thaj. Yog tias lub sijhawm ua txhaum cai ntawm kev ua txhaum ntawm kev muab cov tshuaj insulin, koj yuav tsum ua raws li cov lus qhia thiab yog tias tsim nyog, qhia rau tus kws kho mob. Thaum siv lub twj tso kua mis, npaj Humalog ® yuav tsum tsis txhob sib xyaw nrog lwm cov insulins.
Sab sij huam
Sab nyhuv cuam tshuam nrog cov nyhuv tseem ceeb ntawm cov tshuaj: ntshav qog. Kev mob ntshav khov ntau heev tuaj yeem ua rau tsis nco qab (hypoglycemic coma) thiab, tshwj tsis yog rau kev tuag.
Kev tsis haum tshuaj: kev ua xua nyob hauv zos muaj peev xwm ua tau - liab, o lossis khaus ntawm qhov chaw txhaj tshuaj (feem ntau yuav ploj mus li ob peb hnub lossis ob peb asthiv), kev tsis haum tshuaj (feem ntau tsis tshua muaj, tab sis muaj mob loj dua) - ua kom khaus, ua pob khaus, mob txha caj qaum, ua npaws, ua tsis taus pa, tsawg HELL, tachycardia, nce hws. Cov uas muaj mob hnyav raug neeg lub cev tuaj yeem tas sim neej.
Cov tshuaj tiv thaiv hauv zos: lipodystrophy ntawm thaj chaw txhaj tshuaj.
Cev xeeb tub thiab lactation
Txog rau hnub no, tsis muaj qhov xav tau ntawm Lyspro insulin rau kev xeeb tub lossis kev noj qab haus huv ntawm tus menyuam / tus menyuam tshiab tau pom. Tsis muaj cov kev tshawb fawb nthuav txog kab mob sib kis.
Lub hom phiaj ntawm insulin txoj kev kho mob thaum cev xeeb tub yog tswj hwm cov ntshav qabzib kom txaus rau cov neeg mob ntshav qab zib insulin-los yog mob ntshav qab zib hauv lub ntsej muag. Qhov xav tau rau insulin feem ntau poob qis hauv thawj peb lub hlis thiab nce hauv qib thib ob thiab thib peb thaum cev xeeb tub. Thaum lub sijhawm thiab yug tom qab yug, insulin yuav tsum poob ntau.
Cov poj niam muaj hnub nyoog yug menyuam Cov neeg mob ntshav qab zib yuav tsum qhia lawv tus kws kho mob txog kev xeeb tub uas tab tom npaj lossis npaj ua ntej. Thaum cev xeeb tub, cov neeg mob ntshav qab zib yuav tsum ua tib zoo saib xyuas cov ntshav qabzib, nrog rau kev saib xyuas neeg mob txhua yam.
Hauv cov neeg mob uas mob ntshav qab zib mellitus thaum pub niam mis, yuav tsum tau txhaj tshuaj insulin thiab / lossis noj zaub mov kom haum.
Noj ntau dhau
Cov tsos mob hypoglycemia, nrog rau cov tsos mob hauv qab no: qaug zog, tawm hws ntau, mob tachycardia, mob taub hau, ntuav, tsis meej pem.
Kev Kho Mob: ntshav qab zib tsawg feem ntau nres ntawm kev noj cov piam thaj lossis lwm yam piam thaj, lossis los ntawm cov khoom uas muaj suab thaj.
Kev kho cov ntshav qog ntshav me ntsis tuaj yeem nqa nrog kev pab los ntawm a / m lossis s / c tswj hwm ntawm glucagon, tom qab ntawd kev noj cov zaub mov carbohydrates tom qab ua kom tus neeg mob lub cev ruaj khov. Cov neeg mob uas tsis teb rau glucagon raug muab iv dextrose (glucose) tov.
Yog tias tus neeg mob tsis nco qab, tom qab ntawd glucagon yuav tsum tau txhaj rau hauv / m lossis s / c. Thaum tsis muaj glucagon los sis yog tias tsis muaj tshuaj tiv thaiv rau nws txoj kev tswj hwm, nws yog qhov tsim nyog los qhia qhov kev daws teeb meem ntawm dextrose (piam thaj). Tam sim ntawd tom qab rov qab nco qab, tus neeg mob yuav tsum tau txais cov khoom noj uas muaj carbohydrate-nplua nuj.
Ntxiv rau kev txhawb nqa cov carbohydrate kom tsawg thiab kev saib xyuas tus neeg mob yuav tsum tau ua, raws li Ib qho kev rov qab los ntawm hypoglycemia yog ua tau.
Cov lus qhia Apidra SoloStar rau kev siv
- Chaw tsim tshuaj paus
- Lub teb chaws ntawm tus hauv paus chiv keeb
- Cov Pab Pawg Khoom
- Kev piav qhia
- Tso Tawm Cov Ntawv
- Kev piav qhia ntawm daim ntawv tshuaj
- Pharmacological kev txiav txim
- Cov Tshuaj Pharmacokinetics
- Cov mob tshwj xeeb
- Muaj pes tsawg leeg
- Apidra SoloStar qhia txog kev siv
- Cov Yuav Tsum Tau Ua
- Tsuas tshuaj
- Sab sij huam
- Yeeb tshuaj sib cuam tshuam
- Noj ntau dhau
- Cia rau cov neeg mob
Cov lus thiab cov xwm txheej ntawm kev cia
Sau npe B. Cov tshuaj yuav tsum muab cia kom ncav tsis cuag ntawm cov menyuam yaus, hauv lub tub yees, ntawm qhov txias li 2 ° txog 8 ° C, tsis txhob cia kom khov. Txee lub neej yog 2 xyoos.
Cov tshuaj yeeb hauv kev siv yuav tsum khaws cia hauv chav sov li ntawm 15 ° txog 25 ° C, tiv thaiv los ntawm tshav ntuj ncaj qha thiab kub. Txee lub neej - tsis pub dhau 28 hnub.
Pharmacological ua Humalog
DNA recombinant tib neeg cov tshuaj insulin. Nws txawv ntawm qhov kawg hauv kev rov ua dua ntawm cov amino acids ntawm txoj haujlwm 28 thiab 29 ntawm cov kab hluav taws xob insulin B.
Lub txiaj ntsig tseem ceeb ntawm cov tshuaj yog kev tswj hwm ntawm cov metabolism hauv qab ntuj. Tsis tas li ntawd, nws muaj qhov ua kom anabolic. Hauv cov leeg nqaij, muaj qhov nce ntawm cov ntsiab lus ntawm glycogen, fatty acids, glycerol, kev nce ntawm synthesis protein thiab kev nce ntawm kev noj cov amino acids, tab sis tib lub sijhawm muaj glycogenolysis, gluconeogenesis, ketogenesis, lipolysis, protein catabolism thiab kev tso tawm ntawm cov amino acids.
Hauv cov neeg mob uas muaj hom 1 thiab hom 2 mob ntshav qab zib mellitus, thaum siv cov tshuaj insulin lyspro, hyperglycemia uas tshwm sim tom qab noj mov tau zoo dua yog muab piv nrog kev tiv thaiv tib neeg cov kua dej. Rau cov neeg mob tau txais cov tshuaj insulins luv luv thiab hauv paus, nws yog ib qho tsim nyog yuav tsum xaiv cov koob tshuaj ntawm ob qho insulins thiaj li ua tiav cov ntshav qabzib kom zoo thoob plaws ib hnub.
Ib yam li txhua qhov kev npaj tshuaj insulin, lub sijhawm lyspro insulin ua haujlwm tuaj yeem sib txawv hauv cov neeg mob lossis sijhawm sib txawv ntawm tib tus neeg mob thiab nyob ntawm lub koob tshuaj, chaw txhaj tshuaj, ntshav ntshav, kub cev thiab kev tawm dag zog.
Cov yam ntxwv ntawm lyspro insulin hauv cov menyuam yaus thiab cov hluas yog cov zoo sib xws ntawm cov neeg laus saib.
Hauv cov neeg mob uas muaj ntshav qab zib hom 2 tau txais cov tshuaj sulfonylurea ntau tshaj plaws, qhov ntxiv ntawm lyspro insulin ua rau muaj qhov txo qis hauv glycosylated hemoglobin.
Lyspro insulin kho mob rau cov neeg mob uas muaj yam type 1 thiab ntshav qab zib hom 2 tau nrog ib tug neeg tsawg zuj zus lawm ntawm nocturnal hypoglycemia.
Qhov glucodynamic lo lus teb rau isulin lispro tsis vam khom rau kev ua haujlwm tsis zoo ntawm lub raum lossis nplooj siab.
Lyspro insulin tau pom tias yog ua kom sib luag rau tib neeg cov tshuaj insulin, tab sis nws cov kev ua tshwm sim sai dua thiab kav rau lub sijhawm luv.
Lyspro insulin yog tus cwj pwm los ntawm qhov pib sai ntawm kev coj ua (li 15 feeb), raws li Nws muaj qhov nqus dej siab, thiab qhov no tso cai rau koj nkag mus rau nws tam sim ntawd ua ntej noj mov (0-15 feeb ua ntej noj mov), hauv kev sib piv rau cov pa luv luv ua yeeb yam (30-45 feeb ua ntej noj mov). Lyspro insulin muaj lub sijhawm luv dua (2 mus rau 5 teev) piv rau tib neeg cov tshuaj insulin.
Dosage thiab txoj hauv kev ntawm kev tswj hwm tshuaj.
Tus kws kho mob txiav txim siab muab koob tshuaj ib leeg zuj zus, nyob ntawm qhov xav tau ntawm tus neeg mob. Cov tshuaj Humalog tuaj yeem muab ua ntej ua ntej noj mov, yog tias tsim nyog - sai sai tom qab noj mov.
Qhov ntsuas kub ntawm cov tshuaj tso cai yuav tsum nyob ntawm chav sov.
Qhov tshuaj Humalog yog muab sc nyob rau hauv daim ntawv ntawm kev txhaj tshuaj lossis nyob rau hauv daim ntawv ntawm ncua sc infusion siv lub twj tso kua mis. Yog tias tsim nyog (ketoacidosis, mob hnyav, lub sijhawm ntawm kev ua haujlwm lossis sijhawm hla sijhawm) Humalog tuaj yeem nkag mus rau hauv / hauv.
SC yuav tsum muab rau lub xub pwg, ncej puab, pob tw, lossis plab. Qhov chaw txhaj tshuaj yuav tsum tau hloov chaw kom tib qhov chaw siv tsis ntau tshaj 1 zaug hauv ib hlis. Thaum s / qhia txog cov tshuaj Humalog, kev saib xyuas yuav tsum tau saib xyuas kom tsis txhob txais cov tshuaj rau hauv cov hlab ntsha. Tom qab txhaj tshuaj, qhov chaw txhaj tshuaj yuav tsum tsis txhob zaws. Tus neeg mob yuav tsum tau kawm siv cov txheej txheem kev txhaj tshuaj kom raug.
Cov kev cai rau kev tswj hwm ntawm cov tshuaj Humalog
Npaj rau kev qhia
Kev daws ntawm cov tshuaj Humalog yuav tsum yog pob tshab thiab xim tsis muaj xim. Ib qho huab, tuab lossis xim me ntsis ntawm cov tshuaj, lossis yog tias cov khoom tawg tau pom los rau hauv nws, yuav tsum tsis txhob siv.
Thaum txhim kho lub taub ntim hauv cov koob txhaj tshuaj (tus cwj mem-txhaj), txuas lub koob thiab coj kev txhaj tshuaj insulin, nws yog qhov yuav tsum tau ua raws li cov khw muag cov lus qhia uas txuas nrog txhua tus xaum xim.
2. Xaiv lub xaib rau kev txhaj tshuaj.
3. Antiseptic tawv nqaij ntawm qhov chaw txhaj tshuaj.
4. Tshem tawm lub hau ntawm rab koob.
5. Kho cov tawv nqaij los ntawm kev ncab nws lossis los ntawm kev ruaj ntseg ntawm cov quav loj. Ntxig lub koob txhaj tshuaj raws li cov lus qhia siv kev xaum xim.
6. Nias lub pob ntawd.
7. Tshem tawm rab koob thiab maj mam nyem qhov chaw txhaj tshuaj rau ob peb feeb. Tsis txhob txhuam thaj chaw txhaj tshuaj.
8. Kev siv rab koob rab koob, tshem tawm rab koob thiab rhuav tshem nws.
9. Qhov chaw txhaj tshuaj yuav tsum tau hloov chaw kom qhov chaw qub siv tsis ntau tshaj li 1 zaug hauv ib hlis.
Kev tswj hwm ntawm insulin
Kev txhaj tshuaj tiv thaiv ntawm Humalog yuav tsum tau nqa tawm raws li kev siv tshuaj txhaj rau txoj kev txhaj tshuaj, piv txwv, txhaj tshuaj bolus tswj lossis siv cov txheej txheem infusion. Hauv qhov no, nws yog ib qho tsim nyog feem ntau los tswj cov qib ntawm cov piam thaj hauv cov ntshav.
Lub tshuab ua ke nrog cov ntsiab lus los ntawm 0.1 IU / ml rau 1.0 IU / ml ntawm insulin lispro hauv 0.9% sodium chloride tov lossis 5% dextrose daws yog ruaj khov nyob rau chav sov li 48 teev.
P / C insulin infusion siv lub twj tso kua mis
Rau kev ua txhaum ntawm cov tshuaj Humalog, Minimed thiab Disetronic cov twj tso kua mis tuaj yeem siv rau cov tshuaj insulin. Koj yuav tsum nruj me ntsis ua raws cov lus qhia uas tuaj nrog lub twj tso kua mis. Txoj kev lis ntshav yog hloov pauv txhua 48 teev .Thaum txuas lub infusion system, kev cai aseptic tau pom. Thaum muaj qhov qog ntawm hypoglycemic, Txoj kev lis ntshav yog nres kom txog rau thaum rov zoo. Yog tias pheej rov qab ua lossis txo qis dua cov piam thaj hauv cov ntshav, tom qab ntawd koj yuav tsum qhia koj tus kws kho mob txog qhov no thiab txiav txim siab yuav txo qis lossis tso tseg cov tshuaj insulin. Lub twj tso kua mis tsis ua hauj lwm lossis kev txhaws hauv txoj kev lis ntshav tuaj yeem ua rau nce ntxiv hauv cov piam thaj. Yog tias lub sijhawm ua txhaum cai ntawm kev ua txhaum ntawm kev muab cov tshuaj insulin, koj yuav tsum ua raws li cov lus qhia thiab yog tias tsim nyog, qhia rau tus kws kho mob. Thaum siv lub twj tso kua mis, cov tshuaj Humalog yuav tsum tsis txhob muab sib xyaw nrog lwm cov tshuaj insulins.
Siv thaum cev xeeb tub thiab lactation.
Txog rau hnub no, tsis muaj qhov xav tau ntawm Lyspro insulin rau kev xeeb tub lossis kev noj qab haus huv ntawm tus menyuam / tus menyuam tshiab tau pom. Tsis muaj cov kev tshawb fawb nthuav txog kab mob sib kis.
Lub hom phiaj ntawm insulin txoj kev kho mob thaum cev xeeb tub yog tswj hwm cov ntshav qabzib kom txaus rau cov neeg mob ntshav qab zib insulin-los yog mob ntshav qab zib hauv lub ntsej muag. Qhov xav tau rau insulin feem ntau poob qis hauv thawj peb lub hlis thiab nce hauv qib thib ob thiab thib peb thaum cev xeeb tub. Thaum lub sijhawm thiab yug tom qab yug, insulin yuav tsum poob ntau.
Cov poj niam ntawm lub hnub nyoog yug menyuam uas muaj ntshav qab zib yuav tsum qhia tus kws kho mob txog qhov pib lossis npaj yuav xeeb tub. Thaum cev xeeb tub, cov neeg mob ntshav qab zib yuav tsum ua tib zoo saib xyuas cov ntshav qabzib, nrog rau kev saib xyuas neeg mob txhua yam.
Hauv cov neeg mob uas mob ntshav qab zib mellitus thaum pub niam mis, yuav tsum tau txhaj tshuaj insulin thiab / lossis noj zaub mov kom haum.
Cov lus qhia tshwj xeeb rau kev siv Humalog.
Hloov chaw ntawm tus neeg mob mus rau lwm hom lossis hom tshuaj insulin yuav tsum tau ua raws li kev saib xyuas mob nkeeg nruj me ntsis. Cov kev hloov hauv kev ua, hom (tsim tawm), hom (piv txwv, tsis tu ncua, NPH, Daim kab xev), hom (tsiaj, tib neeg, tib neeg insulin analogue) thiab / lossis cov qauv kev tsim tawm (DNA recombinant insulin lossis insulin ntawm keeb kwm tsiaj) yuav xav tau hloov pauv cov koob tshuaj.
Kev mob uas cov cim qhia ntxov ntawm hypoglycemia yog qhov tsis tseem ceeb thiab tsis tshua hais tawm muaj xws li txuas ntxiv cov ntshav qab zib mellitus, kev kho mob insulin ntau ntxiv, kab mob hauv cov kab mob ntshav qab zib mellitus, lossis tshuaj noj, xws li beta-blockers.
Hauv cov neeg mob uas muaj lub ntsej muag hypoglycemic tom qab hloov los ntawm tsiaj los ntawm cov tshuaj insulin rau tib neeg insulin, cov tsos mob thaum ntxov ntawm hypoglycemia yuav tsis tshua pom los yog txawv ntawm cov kev paub dhau los ntawm lawv cov insulin yav dhau los. Kev tswj tsis tau tus mob hypoglycemic lossis hyperglycemic tshua tuaj yeem ua rau tsis nco qab, tsis nco qab, lossis tuag.
Kev noj tshuaj tsis txaus lossis tsis ua haujlwm ntawm kev kho mob, tshwj xeeb tshaj yog cov tshuaj insulin-mob ntshav qab zib mellitus, tuaj yeem ua rau hyperglycemia thiab ntshav qab zib ketoacidosis, cov xwm txheej uas yuav tsim kev phom sij rau lub neej ntawm tus neeg mob.
Txoj kev xav tau cov tshuaj insulin tuaj yeem txo cov neeg mob lub raum tsis ua haujlwm, zoo ib yam li cov neeg mob lub siab ua haujlwm vim qhov ua haujlwm tsawg kawg ntawm gluconeogenesis thiab insulin metabolism. Txawm li cas los xij, nyob rau hauv cov neeg mob mob siab tsis ua haujlwm ntev, muaj peev xwm tiv thaiv insulin ntau dua tuaj yeem ua rau muaj kev nce ntxiv hauv insulin.
Qhov xav tau ntawm cov tshuaj insulin tuaj yeem nce nrog cov kis kab mob, kev ntxhov siab hauv lub siab, nrog qhov nce ntawm cov carbohydrates hauv cov zaub mov noj.
Yog hais tias tus neeg mob lub cev qoj ib ce ntau zog los yog pauv noj zaub mov zoo ces kuj tseem yuav tsum tau txhaj koob tshuaj. Kev tawm dag zog tam sim ntawd tom qab noj mov tas yuav ua rau muaj ntshav qab zib tsawg dua. Ib qhov tshwm sim ntawm lub pharmacodynamics ntawm kev ua yeeb yam sai sai ntawm insulin analogues yog tias yog tias cov ntshav qog ntshav qab zib, tom qab ntawd nws tuaj yeem txhim kho tom qab txhaj tshuaj dua li thaum txhaj cov tshuaj tiv thaiv tib neeg cov tshuaj insulin.
Tus neeg mob yuav tsum tau ceeb toom tias yog tias tus kws kho mob tau sau ib qho tshuaj insulin nrog kev sib xyaw ntawm 40 IU / ml hauv ib lub vial, ces cov tshuaj insulin yuav tsum tsis txhob noj cov tshuaj cartridge nrog cov tshuaj insulin ntawm 100 IU / ml siv koob txhaj rau insulin nrog rau 40 IU / ml.
Yog tias nws yuav tsum tau noj lwm cov tshuaj tib lub sijhawm uas Humalog, tus neeg mob yuav tsum sab laj nrog kws kho mob.
Cuam tshuam rau kev muaj peev xwm tsav tsheb thiab tswj cov tshuab
Nrog hypoglycemia lossis hyperglycemia cuam tshuam nrog kev noj tshuaj tsis zoo, kev ua txhaum ntawm kev muaj peev xwm mloog zoo thiab qhov ceev ntawm psychomotor cov tshuaj tiv thaiv tuaj yeem tau. Qhov no tuaj yeem dhau los ua kev pheej hmoo rau cov haujlwm muaj kev phom sij (suav nrog kev tsav tsheb lossis kev ua haujlwm nrog tshuab).
Cov neeg mob yuav tsum tau ceev faj kom tsis txhob muaj hypolycemia thaum tsav tsheb. Qhov no yog qhov tshwj xeeb tshaj yog rau cov neeg mob uas muaj qhov txo qis lossis tsis hnov qhov mob ntawm cov tsos mob kwv yees hypoglycemia, lossis hauv leej twg cuam tshuam ntawm hypoglycemia tshwm sim. Hauv cov xwm txheej no, nws yog qhov yuav tsum tau los ntsuas qhov ua tau ntawm kev tsav tsheb. Cov neeg mob ntshav qab zib muaj peev xwm tiv thaiv nws tus kheej los ntawm kev muaj ntshav qabzib tsawg tsawg los ntawm kev noj ntshav qabzib lossis zaub mov ntau hauv carbohydrates (Nws raug nquahu kom koj ib txwm muaj tsawg kawg 20 g piam thaj nrog koj). Tus neeg mob yuav tsum qhia tus kws kho mob uas koom nrog paub txog qhov hloov pauv hypoglycemia.
Humalog sib cuam tshuam nrog lwm yam tshuaj.
Cov nyhuv hypoglycemic yog txo los ntawm kev tiv thaiv qhov ncauj, corticosteroids, thyroid hormone npaj, danazol, beta2-adrenergic agonists (suav nrog rhytodrin, salbutamol, terbutaline), tricyclic antidepressants, thiazide diuretics, chlorprotixenic acid, niacin, diazid derivatives ntawm phenothiazine.
Cov nyhuv hypoglycemic ntawm Humalog yog txhim kho los ntawm beta-blockers, ethanol thiab ethanol-muaj cov tshuaj, anabolic steroids, fenfluramine, guanethidine, tetracyclines, tshuaj tiv thaiv hypoglycemic, salicylates (piv txwv li, acetylsalicylic acid, aniloprilactyl antagonists, MAP inhibitors, Ml. angiotensin II cov neeg txais.
Cov tshuaj tiv thaiv yuav tsum tsis txhob xyaw nrog tsiaj cov tshuaj insulin.
Siv tau cov tshuaj Humalog (nyob rau hauv kev saib xyuas ntawm tus kws kho mob) ua ke nrog kev ua haujlwm ntev ntawm tib neeg cov insulin lossis siv nrog cov tshuaj tiv thaiv kab mob hauv lub qhov ncauj, sulfonylurea derivatives.
Cov lus pom zoo cia ntawm cov tshuaj Humalog.
Sau npe B. Cov tshuaj yuav tsum muab cia kom ncav tsis cuag ntawm cov menyuam yaus, hauv lub tub yees, ntawm qhov txias li 2 ° txog 8 ° C, tsis txhob cia kom khov. Txee lub neej yog 2 xyoos.
Cov tshuaj yeeb hauv kev siv yuav tsum khaws cia hauv chav sov li ntawm 15 ° txog 25 ° C, tiv thaiv los ntawm tshav ntuj ncaj qha thiab kub. Txee lub neej - tsis pub dhau 28 hnub.
- Qhov kev daws teeb meem tsis muaj kob, muaj pob tshab hauv 3 ml cartridges hauv cov hlwv ntim rau hauv pob duab los qhia.
- Lub thawv ntim hauv QuickPen syringe mem (5) yog nyob hauv ib lub thawv ntawv.
- Qhov tshuaj lom neeg Humalog Mix 50 thiab Humalog Mix 25 kuj tseem muaj. Insulin Humalog Mix yog sib xyaw kom muaj vaj huam sib luag ntawm Lizpro ua yeeb yam luv luv insulin thiab Lizpro insulin ncua nrog ncua ntev.
Cov Tshuaj Hauv Tshuaj
Cov tshuaj Insulin Humalog yog DNA hloov kho cov qauv ntawm cov tshuaj insulin. Cov yam ntxwv tshwj xeeb yog kev hloov pauv ntawm kev sib xyaw ntawm cov amino acids nyob rau hauv insulin B saw.
Cov tshuaj tswj cov txheej txheem piam thaj metabolism thiab muaj anabolic sivCov. Thaum qhia rau hauv tib neeg cov leeg nqaij, cov ntsiab lus nce ntxiv glycerol, glycogenfatty acids zoo duaprotein ua kom sib haum, kev noj ntawm cov amino acids yog nce ntxiv, txawm li cas los xij, thaum lub sij hawm zuj zus gluconeogenesis, ketogenesis, glycogenolysis, lipolysistso tawm amino acidsthiab catabolism muaj protein ntau.
Yog tias muaj mob ntshav qab zib mellitus 1thiab2hom ntawmnrog rau kev qhia ntawm cov tshuaj tom qab noj mov, muaj lus tshaj tawm hyperglycemiahais txog kev nqis tes ntawm tib neeg insulin. Lub sijhawm ntawm Lizpro nws txawv thiab nyob ntawm ntau yam - koob tshuaj, ntsuas kub ntawm lub cev, txhaj tshuaj qhov chaw, ntshav qhov ntshav, ua haujlwm ntawm lub cev.
Lizpro insulin cov thawj coj yog nrog los ntawm kev txo qis hauv cov ntu nocturnal hypoglycemia hauv cov neeg mob ntshav qab zib mellitus, thiab nws txoj kev ua piv nrog tib neeg cov tshuaj insulin tshwm sim sai dua (nruab nrab tom qab 15 feeb) thiab kav ntev dua (txij li 2 txog 5 teev).
Cov ntawv qhia ua lus, cov lus qhia rau kev siv
Cov koob tshuaj ntawm cov tshuaj tau teeb tsa ua ib tus zuj zus nyob ntawm qhov rhiab ntawm cov neeg mob mus rau tshuaj exogenous thiab lawv mob. Nws raug nquahu kom qhia cov tshuaj tsis pub dhau 15 feeb ua ntej lossis tom qab noj mov. Cov txheej txheem kev tswj hwm yog tus kheej. Ua li ntawd, tshuaj kub yuav tsum tau nyob theem theem.
Kev ua txhua hnub tuaj yeem sib txawv, muaj ntau qhov ntau rau 0.5-1 IU / kg. Nyob rau yav tom ntej, cov koob tshuaj txhua hnub thiab ib zaug ntawm cov tshuaj tau raug hloov kho nyob ntawm tus neeg mob metabolism thiab cov ntaub ntawv los ntawm ntau cov ntshav thiab cov zis ntsuas cov ntshav qabzib.
Kev tswj hwm kev siv tshuaj ntawm Humalog yog nqa tawm raws li kev txhaj tshuaj rau cov tshuaj tua kabmob. Kev txhaj tshuaj subcutaneous yog tsim nyob rau hauv lub xub pwg, pob tw, ncej puab lossis hauv plab, ntu hloov lawv thiab tsis pub siv qhov chaw ntau tshaj ib hlis ib zaug, thiab qhov chaw txhaj tshuaj yuav tsum tsis txhob zaws. Thaum ua cov txheej txheem, yuav tsum tau saib xyuas kom tsis txhob nkag rau hauv cov hlab ntshav.
Tus neeg mob yuav tsum tau kawm cov txheej txheem txhaj tshuaj kom raug.
Lub ntsiab active tshuaj
Cov tshuaj yog xim tsis muaj kob pob tshab uas tau daws, muab tso rau hauv daim cartridges (1.5, 3 ml) lossis ntim fwj (10 ml). Nws muab tshuaj rau leeg. Cov tshuaj nquag ntawm cov tshuaj yog insulin lispro, diluted nrog cov khoom ntxiv.
Cov khoom siv ntxiv muaj xws li:
- metacresol
- glycerol
- zinc oxide
- sodium hydrogen phosphate,
- 10% hydrochloric acid daws,
- 10% sodium hydroxide tov,
- distilled dej.
Cov tshuaj muaj feem cuam tshuam nrog kev tswj kev ua qabzib, ua cov teebmeem anabolic.
Kev ntsuas ntawm ATC Qib 3
Ntau tshaj peb caug tshuaj nrog cov sib txawv, tab sis zoo sib xws hauv kev ntsuas, txoj kev siv.
Lub npe ntawm qee qhov analogues ntawm Humalog raws li ATC code qib 3:
- Biosulin N,
- Insuman Bazal,
- Protafan
- Humodar b100r,
- Gensulin N,
- Insugen-N (NPH),
- Protafan NM.
Humalog thiab Humalog Mix 50: sib txawv
Qee tus neeg mob ntshav qab zib xav yuam kev tias cov tshuaj no yog kev noj tshuaj tag nrho. Qhov no tsis yog. Qhov nruab nrab tshuaj tiv thaiv Hagedorn (NPH), uas ua rau qeeb qis ntawm kev ua haujlwm ntawm insulin, yog qhia rau hauv Humalog sib tov 50 .
Qhov ntau ntxiv, qhov ntev dua kev txhaj tshuaj ua haujlwm.Nws qhov nrov ntawm cov ntshav qab zib yog vim qhov tseeb tias nws ua kom yooj yim cov kev cai ntawm kev kho tshuaj insulin.
Humalog Sib tov 50 daim cartridges 100 IU / ml, 3 ml hauv Kev Sau Npe Ceev ceev
Tus naj npawb ntawm cov hno txhua hnub txo, tab sis qhov no tsis muaj txiaj ntsig rau txhua tus neeg mob. Nrog rau kev txhaj tshuaj, nws nyuaj rau kev tswj ntshav qab zib kom ua tau zoo. Ib qho ntxiv, cov tshuaj tiv thaiv nruab nrab lub cev Hagedorn feem ntau ua rau ua xua kev tiv thaiv hauv cov neeg mob ntshav qab zib.
Feem ntau, cov tshuaj insulin ntev ntev tau kho rau cov neeg laus, uas, vim muaj cov yam ntxwv ntsig txog lub hnub nyoog, tsis nco qab ua kom mus txhaj tshuaj kom raws sijhawm.
Humalog, Novorapid lossis Apidra - uas yog qhov zoo dua?
Lawv cov mis ua kom zoo dua tuaj yeem ua rau kom muaj suab thaj tsawg dua.
Tib neeg cov kua dej pib ua nyob rau hauv ib nrab ib teev, nws cov tshuaj lom neeg cov tshuaj tiv thaiv rau cov tshuaj tiv thaiv yuav xav tau tsuas yog 5-15 feeb. Humalog, Novorapid, Apidra yog cov tshuaj ultrashort tsim los txo cov ntshav qab zib kom sai.
Ntawm txhua cov tshuaj, qhov haib tshaj yog Humalog. Cov. Nws ua rau cov ntshav qab zib 2.5 zaug ntau dua li cov neeg insulin luv.
Novorapid, Apidra yog qee yam tsis muaj zog. Yog tias koj sib piv cov tshuaj no nrog tib neeg cov tshuaj insulin, nws hloov tawm tias lawv yog 1.5 npaug zog dua li tom kawg.
Kev muab tshuaj tshwj xeeb los kho mob ntshav qab zib yog kws kho mob lub luag haujlwm. Tus neeg mob tau ntsib nrog lwm cov haujlwm uas yuav ua rau nws tiv nrog tus kab mob: nruj mas ua raws, kws kho mob cov lus pom zoo, ua tau zoo.
Related videos
Hais txog cov yam ntxwv ntawm kev siv insulin Humalog hauv video:
DNA recombinant tib neeg cov tshuaj insulin.
Npaj: HUMALOG®
Cov tshuaj nquag ntawm cov tshuaj: tshuaj insulin lyspro
ATX Encoding: A10AB04
KFG: Ua yeeb yam rau neeg lub cev tsis txaus siab
Npe sau npe: P No. 015490/01
Hnub sau npe: 02.02.04
Tswv reg reg. acc .: LAGY FRANCE S.A.S.
Kev daws rau kev txhaj tshuaj yog pob tshab, tsis muaj kob.
1 ml
tshuaj insulin lispro *
100 IU
Cov kev zam: glycerol, zinc oxide, sodium hydrogen phosphate, m-cresol, dej d / thiab, hydrochloric acid tov ntawm 10% thiab sodium hydroxide tov ntawm 10% (los tsim kom muaj qib pH uas yuav tsum tau).
3 ml - cartridges (5) - hlwv (1) - pob khoom los ntawm cardboard.
* Lub npe tsis yog thoob ntiaj teb lub npe pom zoo los ntawm WHO. Hauv Lavxias Lavxias, kev sau tus ntawv lub npe thoob ntiaj teb yog insulin lispro.
Cov lus piav qhia ntawm cov tshuaj yog ua raws cov lus qhia raug pom zoo rau kev siv.
Apidra SoloStar phiv
- Kev mob ntshav qab zib yog qhov ntau tshaj qhov tsis xav tau ntawm kev siv tshuaj insulin, uas tuaj yeem tshwm sim yog tias muaj cov tshuaj insulin ntau dhau lawm yog siv ntau dhau qhov xav tau. Cov kev phiv tshuaj pom nyob rau hauv cov chaw soj ntsuam kuaj mob cuam tshuam nrog kev tswj hwm tshuaj tau teev hauv qab no raws li cov khoom hauv nruab nrog cev thiab hauv kev txiav txim siab txo cov xwm txheej. Thaum qhia txog qhov nquag muaj tshwm sim, cov txheej txheem hauv qab no yog siv: ntau zaus -> 10%, feem ntau -> 1% thiab 0.1% thiab 0.01% thiab Tshuaj sib txuam
Cov kev tshawb fawb txog kev sib txuam ntawm cov tshuaj pharmacokinetic ntawm cov tshuaj tseem tsis tau ua. Raws li txoj kev paub tseeb txog lwm cov tshuaj zoo sib xws, cov tsos mob ntawm kev sib txuam hauv chaw kho mob yog qhov tsis zoo. Qee yam tshuaj yuav cuam tshuam rau cov metabolism hauv qabzib, uas yuav xav tau kho cov tshuaj insulin glulisin thiab tshwj xeeb yog saib xyuas kev kho thiab tus neeg mob lub sijhawm. Thaum siv ua ke, cov tshuaj tiv thaiv kab mob hypoglycemic, ACE inhibitors, disopyramids, fibrates, fluoxetine, MAO inhibitors, pentoxifylline, propoxyphene, salicylates thiab sulfonamide antimicrobials tuaj yeem txhim kho cov nyhuv hypoglycemic ntawm insulin thiab nce cov kab mob siab rau hypoglycemia.
Cov nqi rau Apidra SoloStar hauv lwm lub nroog
Apidra SoloStar hauv Moscow, Apidra SoloStar hauv St. Petersburg, Apidra SoloStar hauv Novosibirsk, Apidra SoloStar hauv Nizhny Novgorod, Apidra SoloStar hauv Kazan, Apidra SoloStar hauv Chelyabinsk, Apidra SoloStar hauv Omsk, Apidar Solara nyob rau hauv Rostov-on-Don, Apidra SoloStar hauv Ufa, Apidra SoloStar hauv Krasnoyarsk, Apidra SoloStar hauv Perm, Apidra SoloStar hauv Voronezh, Apidra SoloStar hauv Krasnodar, Apidra SoloStar hauv Saratov, Apatra, Apid rinburg
Thaum xaj nyob Apteka.RU, koj tuaj yeem xaiv xa mus rau lub tsev muag tshuaj yooj yim rau koj nyob ze koj lub tsev lossis txoj kev ua haujlwm.
Tag nrho cov chaw xa khoom hauv Yekaterinburg - 145 chaw muag tshuaj
EKATERINBURG, TOV * Muaj suab nkauj zoo nkauj * Xyuas | Yekaterinburg, st. Komsomolskaya, d. 17 | 8(343)383-61-95 | txhua hnub txij thaum 09:00 txog 21:00 |
Txhua qhov chaw xa khoom hauv Yekaterinburg
- 145 lub tsev muag tshuaj
Kev tshuaj xyuas txog kev pabcuam Apteka.RU
5 kev ntsuas
A10AB06 Cov tshuaj insulin glulisin
3D duab
Kev daws rau kev tswj hwm ntawm subcutaneous, 100 PIECES / 1 ml | 1 ml |
cov tshuaj nquag: | |
tshuaj insulin glulisin | 100 PIECES (3.49 mg) |
kev zam: metacresol (m-cresol), trometamol (tromethamine), sodium chloride, polysorbate 20, sodium hydroxide, hydrochloric acid, dej rau kev txhaj tshuaj |
Tsuas tshuaj thiab tswj hwm
S / c, luv luv (0-15 feeb) ua ntej lossis tom qab noj mov tas.
Apidra® SoloStar ® yuav tsum tau siv rau hauv kev kho mob uas suav nrog qhov tshuaj nruab nrab lossis insulin ntev ntev lossis kev ua yeeb yam ntev ntev rau insulin. Ib qho ntxiv, Apidra® SoloStar® tuaj yeem siv los ua ke nrog cov tshuaj tiv thaiv kab mob hauv lub qhov ncauj.
Cov tshuaj ntau npaum li cas ntawm tshuaj Apidra® SoloStar ® raug xaiv ib qho zuj zus.
Apidra® SoloStar ® yog muab los ntawm kev txhaj tshuaj sc los yog los ntawm kev nqus ua ntu zus mus rau hauv cov roj subcutaneous uas siv lub twj tso kua mis-nkaus.
Subcutaneous kev txhaj tshuaj ntawm Apidra® SoloStar® yuav tsum tau ua nyob rau thaj tsam ntawm thaj chaw ntawm sab xub ntiag phab ntsa, xub pwg lossis ncej puab, thiab cov tshuaj tau raug tswj los ntawm kev txuas ntxiv mus rau hauv cov rog subcutaneous hauv thaj av ntawm lub xub ntiag ntawm phab ntsa plab. Qhov chaw txhaj tshuaj thiab qhov chaw txhaj tshuaj nyob rau thaj chaw saum toj saud (phab ntsa hauv qab plab, ncej puab lossis xub pwg) yuav tsum tau hloov mus rau txhua txoj kev tswj hwm tshiab ntawm cov tshuaj. Tus nqi ntawm kev nqus thiab, raws li, qhov pib thiab lub sijhawm ua haujlwm tau cuam tshuam los ntawm: qhov chaw tswj hwm, kev siv dag zog thiab lwm yam kev hloov pauv. Kev tswj hwm tus neeg mob mus rau lub plab phab ntsa muab ib qho kev nqus sai dua li kev tswj hwm mus rau lwm qhov chaw hais los saum toj no hauv lub cev (saib ntu "Pharmacokinetics").
Kev ceeb toom yuav tsum tau saib xyuas kom tiv thaiv cov tshuaj los ntawm cov hlab ntshav ncaj qha. Tom qab ua haujlwm ntawm cov tshuaj, nws tsis tuaj yeem ua rau zaws thaj tsam ntawm kev tswj hwm. Cov neeg mob yuav tsum tau kawm txog cov txheej txheem kev txhaj tshuaj kom raug.
Cov tshuaj insulin sib xyaw
Apidra® SoloStar® tuaj yeem sib xyaw nrog tib neeg insulin-isophan.
Thaum tov Apidra® SoloStar ® nrog tib neeg cov tshuaj insulin-isophan, Apidra® SoloStar® yuav tsum yog thawj qhov yuav tsum tau kos rau hauv cov koob txhaj tshuaj. SC txhaj tshuaj yuav tsum tau ua tam sim ntawd tom qab tov. Cov tshuaj tiv thaiv sab saud tsis tuaj yeem raug tswj hwm iv.
Xuas twj tso kua mis rau ua kom tsis tu ncua
Thaum siv Apidra® SoloStar ® nrog lub twj tso kua mis-ua rau kev nqus cov ntshav, nws tsis tuaj yeem tov nrog lwm cov tshuaj.
Apidra® tseem tuaj yeem ua haujlwm siv lub tshuab nqus dej rau lub zog txuas ntxiv sc infusion ntawm insulin. Yog tias tsim nyog, kev npaj Apidra® tuaj yeem tshem tawm daim cartridge ntawm Apidra® SoloStar ® koob txhaj tshuaj thiab siv rau kev tswj hwm los ntawm kev siv lub twj tso kua mis rau qhov sc tas mus li ntawm insulin.
Tib lub sijhawm, Txoj kev lis ntshav thiab cov chaw tso dej siv nrog Apidra® yuav tsum tau hloov nrog cov kev cai aseptic tsawg kawg txhua 48 teev. Cov lus qhia no yuav txawv ntawm cov lus qhia dav dav hauv cov lus qhia rau kev siv twj tso kua mis. Nws yog ib qho tseem ceeb uas cov neeg mob ua raws li cov lus qhia tshwj xeeb saum toj no rau kev siv Apidra®. Tsis ua raws li cov lus qhia tshwj xeeb no rau kev siv Apidra® tuaj yeem ua rau muaj kev txhim kho ntawm qhov tshwm sim tsis zoo.
Thaum siv Apidra ® nrog lub twj tso kua mis-ua rau kev txuas ntxiv sc infusion ntawm insulin, nws tsis tuaj yeem sib xyaw nrog lwm cov insulins lossis cov kuab tshuaj.
Cov neeg mob uas tau txais kev tswj hwm Apidra® los ntawm kev ua kom tsis tu ncua sc infusion yuav tsum muaj lwm txoj hauv kev rau cov tshuaj insulin thiab yuav tsum tau kawm hauv insulin tswj hwm los ntawm sc txhaj tshuaj (nyob rau hauv kev sib tsoo ntawm lub twj tso kua mis siv).
Thaum siv Apidra® nrog cov twj tso kua mis rau kev txuas ntxiv txuas ntxiv ntawm insulin, cuam tshuam ntawm lub twj tso kua mis, ua haujlwm tsis zoo ntawm txoj kev lis ntshav, lossis yuam kev hauv kev tuav tau sai yuav ua rau kev txhim kho hyperglycemia, ketosis, thiab ketoacidosis uas mob ntshav qab zib. Nyob rau hauv cov ntaub ntawv ntawm kev loj hlob ntawm hyperglycemia lossis ketosis lossis ntshav qab zib ketoacidosis, kev txheeb xyuas sai thiab tshem tawm ntawm cov laj thawj ntawm lawv txoj kev loj hlob yog xav tau.
Ua raws li cov lus qhia txog kev saib xyuas kom zoo ntawm cov koob txhaj ua ntej (saib ntu "Cov lus qhia rau kev siv thiab tuav").
Cov lus qhia rau kev siv thiab tuav ntawm cov xoos sau ua ntej SoloStar® koob txhaj tshuaj
Ua ntej siv thawj zaug, rab koob xaum xaum yuav tsum khaws cia ntawm chav tsev li 1-2 teev.
Ua ntej siv, tshawb xyuas daim cartridge sab hauv daim ntawv xaum. Nws yuav tsum siv tsuas yog hais tias qhov kev daws teeb meem yog pob tshab, xim, tsis muaj qhov pom ntawm cov khoom thiab thiab zoo sib xws, cuam tshuam nrog dej.
Lub cev tsis siv SoloStar ® cov koob txhaj tshuaj yuav tsum tsis tau siv thiab muab pov tseg.
Txhawm rau tiv thaiv kev kis mob, tus cwj mem uas muaj menyuam qhwv ua ntej tsuas yog siv los ntawm ib tus neeg mob thiab yuav tsum tsis txhob hloov mus rau lwm tus.
Kev Siv SoloStar® Syringe Cwj mem
Ua ntej siv SoloStar® koob txhaj tshuaj, koj yuav tsum ua tib zoo nyeem cov lus qhia rau kev siv.
Cov ntaub ntawv tseem ceeb ntawm kev siv SoloStar® Syringe Cwj mem
Ua ntej siv txhua qhov, ua tib zoo txuas lub koob tshiab rau daim duab xaum xaum thiab kev sim kev nyab xeeb. Tsuas siv cov koob uas txuam nrog SoloStar ® yuav tsum siv.
Cov kev tiv thaiv tshwj xeeb yuav tsum tau ceev faj kom tsis txhob muaj kev sib tsoo nrog kev siv koob thiab qhov kis tau ntawm kev kis tus kab mob.
Tsis txhob siv lub SoloStar® koob txhaj tshuaj yog tias nws puas ntsoog lossis yog koj tsis paub meej tias nws yuav ua haujlwm tau zoo.
Txhua lub sijhawm muaj cov SoloStar® koob txhaj tshuaj nyob hauv tes thaum poob lossis puas rau cov quav uas siv.
Kev qhia cia
Yog tias SoloStar® koob txhaj tshuaj yuav tsum tau muab cia rau hauv tub yees, nws yuav tsum tau muab tshem tawm los ntawm 1-2 teev ua ntej kev txhaj tshuaj kom daws tau qhov chaw sov. Kev tswj hwm cov tshuaj chine chilled yog qhov mob ntau dua.
Kev siv SoloStar® Syringe Pen yuav tsum tau muab rhuav pov tseg.
SoloStar® koob txhaj tshuaj yuav tsum tiv thaiv cov plua tshauv thiab av.
Sab nraud ntawm SoloStar® Syringe Pen tuaj yeem ntxuav los ntawm kev so nws nrog daim ntaub noo.
Tsis txhob pleev dej rau hauv dej, yaug thiab roj SoloStar® koob txhaj tshuaj, vim qhov no tuaj yeem ua rau nws puas.
SoloStar ® Syringe Pen siv cov tshuaj insulin kom raug thiab nyab xeeb siv. Nws tseem yuav tsum tau ua tib zoo saib xyuas. Zam zam cov xwm txheej uas ua rau SoloStar ® koob txhaj tshuaj yuav tshwm sim.Yog tias muaj kev ntseeg tias SoloStar® koob txhaj tshuaj yuav raug puas ntsoog, siv tus cwj mem tshiab.
Theem 1. Tshuaj Insulin
Koj yuav tsum kos daim ntawv lo rau ntawm SoloStar® Syringe Cwj mem kom paub tseeb tias nws muaj cov insulin tseeb. Tom qab hle lub hau ntawm rab koob txhaj tshuaj, cov tsos ntawm cov tshuaj insulin nyob hauv nws yog tswj: cov tshuaj insulin yuav tsum muaj pob tshab, tsis muaj xim, tsis muaj cov khoom ua kom pom thiab zoo li dej nyob hauv xwm yeem.
Theem 2. Txuas rab koob
Tsuas yog siv cov koob uas txuam nrog SoloStar® koob txhaj tshuaj xwb yuav tsum tau siv.
Txog kev txhaj txhua zaus, yuav tsum siv rab koob tshiab tshiab uas tsis huv. Tom qab hle lub hau tawm, rab koob yuav tsum tau muab ntsia kom zoo ntawm daim duab syringe.
Theem 3. Kev Ntsuas Kev Nyab Xeeb
Ua ntej txhua txoj kev txhaj tshuaj, nws yog qhov yuav tsum tau ua qhov kev ntsuas kev nyab xeeb thiab ua kom cov koob txhaj tshuaj ua haujlwm zoo thiab cua tshuab tau tshem tawm.
Ntsuas cov koob tshuaj sib npaug rau 2 PIECES.
Cov kaus mom uas siv sab nraud thiab sab hauv yuav tsum tau muab tshem tawm.
Muab tus cwj mem ntim nrog rab koob, maj mam muab coj mus rhaub rau ntawm daim laub insulin nrog koj tus ntiv tes kom txhua lub npuas huab cua txav mus rau ntawm rab koob.
Nias (tag nrho) khawm txhaj.
Yog tias muaj cov tshuaj insulin rau ntawm qhov kawg ntawm rab koob, qhov no txhais tau tias rab koob xaum thiab rab koob ua hauj lwm zoo.
Yog tias cov tshuaj insulin tsis tshwm sim rau ntawm lub ntsis ntawm rab koob, tom qab ntawd cov kauj ruam 3 rov ua dua kom txog thaum cov insulin tshwm ntawm qhov taub ntawm rab koob.
Theem 4. Xaiv Xaiv
Qhov koob tshuaj tuaj yeem tsim nrog qhov tseeb ntawm 1 UNIT, los ntawm qhov tsawg kawg nkaus koob tshuaj (1 UNIT) mus txog qhov siab tshaj (80 UNIT). Yog tias nws yuav tsum los qhia qhov tshuaj tshaj li ntawm 80 tus PIECES, yuav tsum txhaj 2 koob los yog ntau dua.
Lub koob tshuaj yuav tsum kos npe "0" tom qab kev ntsuas kev nyab xeeb tiav. Tom qab ntawd, cov koob tshuaj tsim nyog tau tsim muaj.
Theem 5. Ceeb Toom
Tus neeg mob yuav tsum tau qhia rau cov txheej txheem txhaj tshuaj los ntawm tus kws kho mob paub.
Lub koob yuav tsum tau muab tso rau hauv qab daim tawv nqaij.
Lub pob txhaj tshuaj yuav tsum nias tag nrho. Nws tau tuav hauv txoj haujlwm no rau lwm 10 s kom txog thaum lub koob tau muab tshem tawm. Qhov no ua kom paub tseeb ntawm qhov kev xaiv ntawm xaiv koob tshuaj insulin kiag li.
Theem 6. Tshem thiab tshem tawm ntawm rab koob
Txhua qhov xwm txheej, tom qab txhua zaus txhaj koob, rab koob yuav tsum tau muab tshem tawm thiab pov tseg. Qhov no ua kom muaj kev tiv thaiv ntawm kev sib kis thiab / lossis kis tau tus mob, cua nkag mus rau hauv lub thawv rau tshuaj insulin thiab paim ntshav ntawm insulin.
Thaum hle thiab pov tseg lub koob, yuav tsum muaj kev tiv thaiv tshwj xeeb. Cov lus qhia txog kev nyab xeeb kev nyab xeeb kom tshem tawm thiab pov tawm rab koob (piv txwv, cov txheej txheem ntawm muab tso rau ntawm lub hau nrog ib txhais tes) yuav tsum tau pom zoo kom txo qis kev pheej hmoo ntawm kev sib tsoo nrog kev siv rab koob thiab tseem tuaj yeem tiv thaiv kev kis mob.
Tom qab tshem rab koob, kaw SoloStar® koob txhaj tshuaj nrog lub hau.
Cov pab pawg neeg tshwj xeeb
Lub raum khiav tsis zoo. Txoj kev xav tau cov tshuaj insulin hauv lub raum tsis ua haujlwm yuav poob qis.
Lub siab ua haujlwm tsis zoo. Hauv cov neeg mob uas muaj lub siab ua haujlwm tsis txaus siab, qhov xav tau rau insulin tuaj yeem txo vim muaj peev xwm txo qis gluconeogenesis thiab ua rau cov metabolism hauv insulin qeeb qeeb.
Cov neeg laus cov neeg mob. Muaj cov ntaub ntawv pharmacokinetics hauv cov neeg laus uas muaj ntshav qab zib mellitus yog qhov tsis txaus. Lub raum khiav tsis zoo hauv lub hnub nyoog laus tuaj yeem ua rau txo qis hauv insulin.
Menyuam yaus thiab tub ntxhais hluas. Apidra® tuaj yeem siv rau hauv cov menyuam yaus tshaj li 6 xyoo thiab cov hluas. Cov ntaub ntawv kev soj ntsuam txog kev siv cov tshuaj rau cov menyuam yaus hnub nyoog qis dua 6 xyoo yog txwv.
Npaum li cas thiab ntau npaum li cas los ntaus nws?
Humalog sai dua li lwm cov tshuaj tuaj yeem kho cov ntshav qab zib kom ntshav khov. Yog li ntawd, nws yog qhov zoo tshaj kom muaj nws nrog koj thaum muaj xwm txheej. Txawm li cas los xij, qee tus neeg mob ntshav qab zib tau kam siv cov tshuaj insulin luv luv thiab ultrashort.Yog tias koj tswj hwm koj cov piam thaj hauv cov ntshav qis nrog kev noj zaub mov kom tsawg, koj tuaj yeem yuav los ntawm cov yeeb tshuaj luv luv.
Ntev npaum li cas rau kev txhaj tshuaj?
Txhua qhov txhaj ntawm cov tshuaj Humalog yuav siv li 4 teev. Tus mob ntshav qab zib uas ua raws li yuav tsum tau txhaj tshuaj insulin tsawg kawg. Nws feem ntau yuav tsum tau diluted kom raug txhaj ib koob uas tsawg dua 0.5-1 ib pawg. Tib neeg cov lus qhia tuaj yeem ua tsis tau tsuas yog rau cov menyuam yaus uas muaj ntshav qab zib hom 1, tab sis kuj rau cov neeg mob laus. Vim tias nws yog ib cov tshuaj uas muaj zog heev. Thaum siv cov tshuaj tsawg kawg, insulin nres ua haujlwm sai dua li teev hauv cov lus qhia ntawm nom tswv. Tej zaum qhov kev txhaj tshuaj yuav tas rau hauv 2.5-3 teev.
Tom qab txhaj txhua yam ntawm kev npaj ultrashort, ntsuas ntshav qab zib kom tsis muaj ntxov dua 3 teev tom qab. Vim tias txog lub sijhawm no, cov koob tshuaj insulin tsis muaj sijhawm tsis txaus los qhia nws cov nyhuv tag nrho. Raws li txoj cai, cov kabmob ntshav qab zib tau txhaj cov tshuaj insulin sai, noj, thiab tom qab ntawd ntsuas ntsuas qab zib ua ntej noj mov tom ntej. Tsuas yog nyob hauv cov xwm txheej uas tus neeg mob hnov. Hauv cov xwm txheej zoo li no, koj yuav tsum tau soj ntsuam tam sim ntawd txog qib piam thaj hauv cov ntshav thiab, yog tias tsim nyog, nqis tes ua.
Cov tshuaj insulin twg zoo dua: Humalog lossis NovoRapid?
Tej zaum yuav tsis muaj cov ntaub ntawv raug los teb cov lus nug no, uas feem ntau cov neeg mob tau nug. Vim tias ntau hom insulin cuam tshuam rau txhua tus ntshav qab zib ib tus zuj zus. Zoo li Humalog, lawv muaj ntau tus kiv cua. Raws li txoj cai, cov neeg mob txhaj tshuaj uas lawv tau pub dawb.
Kev fab tshuaj yuam kom qee leej hloov los ntawm ib hom tshuaj insulin mus rau lwm tus. Peb rov hais dua, yog tias soj ntsuam sai li insulin ua ntej noj mov, nws zoo dua yog siv tshuaj yeeb-luv luv, piv txwv li, dua li ntawm ultrashort Humalog, NovoRapid lossis Apidra. Yog tias koj xav xaiv qhov zoo tshaj plaws ntawm kev txuas ntxiv thiab ceev insulin, ces koj tsis tuaj yeem ua yam tsis muaj kev sim siab thiab qhov tsis raug.
Cov tshuaj ntxiv ntawm cov tshuaj insulin Humalog (lispro) - cov no yog cov tshuaj thiab. Cov qauv ntawm lawv cov lwg me me nws txawv, tab sis rau kev coj ua nws tsis txawv. thov tias Humalog ua nrawm dua thiab muaj zog dua nws cov neeg ua haujlwm. Txawm li cas los xij, tsis yog txhua tus neeg mob lees paub cov ntaub ntawv no. Ntawm cov ntawv sib tham ntawm Lavxias-hais txog tus mob ntshav qab zib, koj tuaj yeem nrhiav cov lus tsis txaus ntseeg.
Cov neeg mob uas muaj ntshav qab zib hom 1 thiab ntshav qab zib hom 2 uas tau soj ntsuam zoo yuav sim hloov cov tshuaj insulin lispro nrog cov tshuaj tiv thaiv luv luv. Piv txwv li, ntawm. Saum toj no nws tau sau hauv kev nthuav dav yog vim li cas qhov no tsim nyog ua. Ntxiv mus, luv luv insulin yog pheej yig dua. Vim tias nws tau nkag mus rau tom khw ntau xyoo dhau los.
Chaw tsim tshuaj paus
1. Sanofi-Aventis Deutschland GmbH, Lub Tebchaws Yelemees.
2. CJSC Sanofi-Aventis Vostok, Russia. 302516, Russia, Oryol Koog, Oryol Koog Tsev Kawm, s / n Bolshekulikovskoye, ul. Livenskaya, 1.
Kev thov cov neeg tau txais kev pabcuam yuav tsum raug xa mus rau qhov chaw nyob ntawm tus neeg sawv cev chaw haujlwm hauv tebchaws Russia: 125009, Moscow, ul. Tverskaya, 22.
Xov Tooj: (495) 721-14-00, fev: (495) 721-14-11.
Xws li kev tsim cov tshuaj ntawm Sanofi-Aventis Vostok CJSC, Russia, cov neeg tsis txaus siab yuav tsum xa mus rau qhov chaw nyob nram qab no: 302516, Russia, Oryol Thaj Chaw, Oryol District, s / n Bolshekulikovskoye, ul. Livenskaya, 1.
Tel./fax: +7 (486) 244-00-55.
Apidra yog ib cov tshuaj ntawm dab tsi txiav txim?
Coob leej ntseeg tias Apidra yog cov tshuaj insulin luv luv. Qhov tseeb, nws yog cov tshuaj ultrashort. Nws yuav tsum tsis txhob tso siab nrog actrapid insulin, uas yog luv heev. Tom qab kev coj ua, ultra-luv Apidra pib ua nrawm dua li npaj luv. Tsis tas li, nws kev txiav txim sai.
Tshwj xeeb, luv hom insulin pib ua 20-30 feeb tom qab txhaj tshuaj, thiab ultrashort Apidra, Humalog thiab NovoRapid - tom qab 10-15 feeb. Lawv txo lub sijhawm uas tus mob ntshav qab zib yuav tsum tau tos ua ntej noj mov. Cov ntaub ntawv yog cov cim. Txhua tus neeg mob tau nws tus kheej pib lub sijhawm thiab lub zog ntawm kev ua ntawm cov tshuaj insulin. Ntxiv nrog rau cov tshuaj siv, lawv nyob ntawm qhov chaw txhaj tshuaj, cov roj hauv lub cev thiab lwm yam.
Thov nco ntsoov tias cov neeg mob ntshav qab zib uas ua raws li kev noj zaub mov kom tsawg, noj cov tshuaj insulin ua ntej noj mov yuav zoo dua li cov tshuaj ultrashort. Qhov tseeb yog tias cov zaub mov tsis muaj carb uas zoo rau cov ntshav qab zib tau maj mam nqus los ntawm lub cev. Apidra tuaj yeem pib ua kom cov piam thaj qis dua li qhov noj protein uas tau noj yog zom thiab ib feem ntawm nws hloov mus ua qabzib. Vim muaj qhov sib txawv ntawm qhov ceev ntawm kev ua ntawm insulin thiab kev ua kom yoo ua zaub mov, cov ntshav qab zib yuav poob ntau dhau, thiab tom qab ntawd sawv los ntawm kev rov ua dua. Xav txog kev hloov ntawm cov tshuaj insulin Apidra rau ib qho yeeb tshuaj luv luv, xws li Actrapid NM.
Lub caij nyoog ntawm kev txhaj tshuaj no yog dab tsi?
Txhua koob txhaj ntawm insulin Apidra siv tau ntev li 4 teev. Lub voj voos nyob ntev li 5-6 teev, tab sis nws tsis tseem ceeb. Lub ncov ntawm kev nqis tes yog tom qab 1-3 teev. Ntsuas qab zib dua tsis ntev dua 4 teev tom qab kev txhaj tshuaj insulin. Txwv tsis pub, qhov koob tshuaj uas tau txais ntawm lub cev tsis muaj sijhawm txaus los ua. Sim tsis txhob pub ob lub koob txhaj tshuaj tiv thaiv insulin kom txaus rau hauv cov ntshav thaum tib lub sijhawm. Rau qhov no, kev txhaj tshuaj ntawm Apidra yuav tsum tau ua nyob rau ntawm ntu ua ke tsawg kawg 4 teev.
Nyeem txog cov khoom rau cov ntshav qab zib: Cov Txiv Hmab Txiv Ntoo muv zib ntab Porridge Butter thiab roj zaub