Gentamicin kev txhaj tshuaj: cov lus qhia rau kev siv
Gentamicin sulfate belongs rau cov pab pawg ntawm aminoglycosides, muaj kev pom dav ntawm kev ua, ua ib qho tshuaj tua kab mob ntawm cov kab mob kev ua haujlwm.
Cov tshuaj ua rau pom kev ua haujlwm nce ntxiv los tiv thaiv cov kab mob gram-negative aerobic: Shigella, E. coli, Salmonella, Enterobacter, Klebsiella, Protein, Pseudomonas aeruginosa. Gentamicin tseem ua tawm tsam staphylococci (txawm tias cov uas tiv taus lwm yam tshuaj tua kab mob, penicillin), qee yam ntawm streptococci.
Kev tiv thaiv rau cov tshuaj tiv thaiv mob meningococcus, daj ntseg treponema, qee hom streptococci, kab mob anaerobic.
Cov lus qhia rau kev siv Gentamicin
Gentamicin raws li cov lus qhia yog sau rau cov mob xws li:
- mob txeeb zig: cystitis, mob rwj, pyelonephritis,
- kev ua pa tawm: empyema, mob ntsws qhuav, pleurisy, mob ntsws,
- phais mob: mob ntshav lom, mob peritoneal,
- tawv nqaij: dermatitis, ntau yam purulent o, mob rwj, txhaws.
Cov lus qhia rau kev siv Gentamicin
Kev siv cov Gentamicin yog qhov zoo tshaj plaws tom qab txiav txim siab rhiab rau nws ntawm microflora uas ua rau muaj tus kabmob.
Cov lus qhia tau qhia qhov ntsuas thaj tsam nruab nrab uas siv rau kev kho mob:
- nrog rau cov mob txeeb zig rau cov hluas tshaj 14l. thiab rau cov laus, ib koob tshuaj yog 0.4 mg rau ib phaus ntawm lub cev qhov hnyav, thiab ib koob tshuaj txhua hnub yog 0.8-1.2 mg rau ib phaus ntawm tus neeg mob lub cev.
- Nrog sepsis thiab lwm yam kev kis mob hnyav, ib koob tshuaj yog 0.8-1 mg rau ib phaus, thiab cov koob tshuaj txhua hnub yog 2.4-3.2 mg.
Qhov tshuaj ntau ntau yog 5 mg rau ib phaus ib hnub.
Cov menyuam yaus hnub nyoog qis dua 14 xyoos Gentamicin sulfate tsuas yog muaj rau kev ntsuas tshwj xeeb.
Qhov tshuaj rau txhua hnub rau cov menyuam mos thiab cov menyuam mos yog 2-5 mg rau ib phaus ntawm qhov hnyav. Cov menyuam yaus los ntawm 1-5l. tsa li 1.5-3.0 mg rau ib phaus, menyuam yaus 6-14 litres. - 3 mg rau ib phaus.
Qhov ntau tshaj plaws ntawm cov tshuaj Gentamicin rau cov menyuam yaus ntawm cov hnub nyoog sib txawv yog 5 mg / kg / hnub.
Qhov koob tshuaj txhua hnub feem ntau yog muab faib ua ob rau peb koob. Ntawm chav kawm, nyob rau nruab nrab, kav ntev li 7-10 hnub. Gentamicin kev txhaj tshuaj feem ntau yog muab 2-3 hnub tso rau hauv cov tshuaj, thiab tom qab ntawd lawv hloov mus rau kev txhaj tshuaj intramuscular.
Rau kev tswj hwm intramuscularly, Gentamicin sulfate siv nyob rau hauv daim ntawv ntawm cov tshuaj tov npaj lossis 2 ml diluted. dej tsis huv hmoov. Rau kev txhaj tshuaj ntawm cov tshuaj Gentamicin, koj tuaj yeem siv tsuas yog cov tshuaj npaj tau.
Gentamicin lee los yog tshuaj pleev yog siv rau cov tawv nqaij purulent o, folliculitis, furunculosis. Nyob rau tib lub sijhawm, thaj chaw cuam tshuam tau smeared nrog ob mus rau peb r / hnub rau ib mus rau ob lub lis piam.
Nrog rau cov mob ua ke, keratitis, lwm yam kab mob kis rau lwm qhov muag, cov tee Gentamicin tau siv - peb mus rau plaub r / hnub.
Sab sij huam
Kev siv cov Gentamicin tuaj yeem ua rau muaj kev mob tshwm sim xws li: ntuav, xeev siab, hyperbilirubinemia, kev ua haujlwm ntau ntawm hepatic transaminases, proteinuria, microhematuria, oliguria, lub raum tsis ua haujlwm, mob taub hau, tsis hnov lus, tsis hnov qab, lag ntseg, tsis tuaj yeem mob, mob pob ntseg kub taub hau, khaus, Quincke's edema (tsis tshua muaj).
Cov Yuav Tsum Muaj
Cov lus qhia ntawm Gentamicin qhia tau tias nws qhov kev siv yog contraindicated yog tias tus neeg mob tau tso tshuaj tiv thaiv kab mob rau tag nrho cov tshuaj tua kab mob ntawm aminoglycoside pawg.
Tsis tas li ntawd, Gentamicin tsis yog siv rau neuritis ntawm cov neeg hnov mob hlab ntsha, mob hnyav tsis zoo rau lub raum, cev xeeb tub, lactation, uremia.
Gentamicin: cov nqi hauv cov khw muag tshuaj online
Gentamicin 40 mg / ml daws rau kev tso dej thiab cov tshuaj intramuscular ntawm 2 ml 10 pcs.
Gentamicin 40 mg / ml daws rau kev tso dej thiab cov tshuaj intramuscular ntawm 2 ml 10 pcs.
Gentamicin 40 mg / ml daws rau kev tso dej thiab tshuaj intramuscular 2 ml 5 pcs.
GENTAMICIN 40 mg / ml 2 ml 10 pcs. kev daws rau kev tso ntshav thiab intramuscular
GENTAMICIN 40 mg / ml 2 ml 10 pcs. kev daws rau kev tso ntshav thiab intramuscular
GENTAMICIN 0.1% 15g tshuaj pleev rau kev siv sab nraud
Cov ntaub ntawv hais txog cov tshuaj raug muab dav dav, muab rau kev qhia tawm thiab tsis hloov chaw cov lus qhia. Kev siv tshuaj rau tus kheej yog qhov txaus ntshai rau kev noj qab haus huv!
Muaj 74 xyoo nyob hauv tebchaws Australian yawg James Harrison tau los ua neeg muab ntshav li 1,000 zaus. Nws muaj cov ntshav uas tsis tshua muaj ntshav ntau, cov tshuaj tiv thaiv txhawm rau pab cov menyuam mos uas muaj ntshav tsawg txaus kom ciaj sia taus. Yog li, Australian thiaj cawm tau ntau txog ob lab tus menyuam.
Nrog kev mus saib xyuas lub txaj tanning, txoj kev pheej hmoo ntawm kev mob qog tawv nqaij yuav nce 60%.
Cov kws kho hniav tau tshwm sim tsis ntev los no. Rov qab rau hauv lub xyoo pua puv 19, nws yog lub luag haujlwm ntawm tus kws tu plaub hau kom rub tawm cov hniav mob.
Hauv tebchaws Askiv, muaj txoj cai lij choj raws li uas tus kws phais neeg tuaj yeem tsis kam ua haujlwm rau tus neeg mob yog tias nws haus luam yeeb lossis rog dhau. Ib tus neeg yuav tsum tso tawm tus cwj pwm tsis zoo, thiab tom qab ntawd, tej zaum, nws yuav tsis xav tau kev phais mob.
Qhov ua kom pom kev vibrator ua ntej nyob rau xyoo 19th. Nws ua haujlwm ntawm lub tshuab tso hluav taws xob thiab nws tau npaj kho qhov mob poj niam.
Muaj ntau cov kev kho mob nthuav tawm heev, xws li kev siv khoom tsis nco qab ntawm cov khoom. Hauv plab ntawm ib tus neeg mob uas tau mob los ntawm tus txiv neej no, 2500 cov khoom txawv teb chaws tau pom.
Caries yog hom kis tau yooj yim tshaj plaws hauv ntiaj teb uas txawm tias tus mob npaws tsis tuaj yeem sib tw nrog.
Cov kws tshawb fawb Asmeskas tau sim cov nas thiab tau xaus lus tias cov kua txiv mab txiv ntoo txwv tsis pub muaj kev txhim kho ntawm cov hlab ntshav ntawm cov ntshav. Ib pawg nas haus dej dawb, thiab lub thib ob ua kua txiv. Raws li qhov tshwm sim, cov hlab ntsha ntawm cov pab pawg thib ob yog pub dawb cov plahaum roj.
Kev ua haujlwm uas ib tus neeg tsis nyiam yuav muaj kev phom sij rau nws lub siab ntau dua li qhov uas tsis muaj haujlwm hlo li.
Txhawm rau hais txawm tias cov lus luv thiab yooj yim, peb siv 72 leeg leeg.
Yog tias koj lub siab ua haujlwm, kev tuag yuav tshwm sim hauv ib hnub.
Yog tias koj luag nyav tsuas yog ob zaug ib hnub, koj tuaj yeem txo cov ntshav siab thiab txo qhov kev pheej hmoo ntawm lub plawv thiab mob nkees.
Thaum lub neej, tus neeg nruab nrab tsim tawm tsis tsawg tshaj li ob lub pas dej loj uas muaj qaub ncaug.
Raws li ntau tus kws tshawb fawb, cov vitamins complex yog qhov tsis muaj txiaj ntsig rau tib neeg.
Tus neeg muaj kev kawm paub tsis yooj yim rau cov kab mob hlwb. Cov kev txawj ntse ua haujlwm koom nrog kev tsim cov ntaub so ntswg ntxiv los txhawb rau cov neeg mob.
Raws li kev txheeb cais, kwv yees li 80% ntawm cov poj niam hauv Lavxias txom nyem mob los ntawm kab mob vaginosis. Raws li txoj cai, tus kab mob tsis kaj siab no tau nrog los ntawm dawb los yog txho outflows.
Tso tawm daim ntawv thiab muaj pes tsawg leeg
Ib qho kev daws teeb meem rau kev tswj hwm parenteral Gentamicin yog cov kua ntshiab, tsis muaj xim. Nws muaj nyob hauv 2 ml iav ampoules. Ib qho ampoule muaj 80 mg ntawm gentamicin sulfate ua lub ntsiab lus tseem ceeb xyaw. Ampoules yog ntim rau hauv cov hlwv hauv qhov nyiaj ntawm 10 daim. Daim npav pob ntawv muaj ib qho blister sawb ntim thiab cov lus qhia rau kev siv tshuaj.
Tsuas tshuaj thiab tswj hwm
Gentamicin Txhaj Tshuaj Tiv Thaiv yog muab tshuaj intramuscularly lossis intravenously. Qhov pom zoo rau kev noj tshuaj txhua hnub yog 3-5 mg / kg lub cev qhov hnyav, muab faib ua 3 koob. Qhov nruab nrab ntawm kev kho mob yog 7-10 hnub, yog tias tsim nyog, tus kws kho mob tuaj yeem txuas ntxiv cov tshuaj tua kab mob rau ob peb hnub. Kuj tseem muaj cov qauv ua rau kev tswj hwm ntawm cov tshuaj Gentamicin daws nyob rau hauv ib qho nyiaj ntawm 160 mg (2 ampoules) ib hnub ib zaug, nyob rau hauv chav kawm ntawm 7-10 hnub. Hauv kev kis mob hnyav, qhov kev poob siab ntau tshaj 240 mg ntawm cov tshuaj tua kab mob (3 ampoules) yog txhaj ib zaug. Rau cov menyuam yaus hnub nyoog dhau 2 xyoos, kev siv tshuaj txhua hnub yog zoo ib yam rau cov neeg laus - 3-5 mg / kg lub cev hnyav. Rau cov menyuam yug lossis cov menyuam tsis tau yug hnub, koob txhua hnub yog 2-5 mg / kg lub cev qhov hnyav, nws tau faib ua 2 koob. Rau cov menyuam hnub nyoog qis dua 2 xyoos, tau muab tib koob tshuaj ua 3 koob. Nrog rau lub raum tsis ua haujlwm, qhov koob tshuaj Gentamicin daws tau yog qhov tseeb, nyob ntawm qhov mob hnyav ntawm qhov txo qis rau hauv lub luag haujlwm ntawm lub raum.
Sab sij huam
Kev siv txoj hauv kev daws teeb meem rau kev tswj hwm ntawm tsoomfwv ntawm Gentamicin tuaj yeem ua rau kev txhim kho kev phiv los ntawm ntau yam kabmob thiab cov tshuab:
- Cov kab mob zom zaws - xeev siab, ntuav, tso quav tsis ruaj.
- Mob leeg - mob taub hau, tsaug zog, kiv taub hau.
- Cov kab mob hauv lub tso zis - cov proteinuria (cov tsos ntawm cov protein nyob hauv cov zis), cylindruria (qhov zoo li cov pov ntawm cov hlaus rov qab rau hauv cov zis hauv daim ntawv ntawm lub tog raj kheej), kev txhim kho lub raum tsis ua haujlwm.
- Cov hlwb pob txha thiab cov ntshav liab - ntshav liab (txo ntshav tsawg thiab ntshav liab), granulocytopenia (txo qis hauv qee cov qe ntshav dawb hauv cov ntshav, tshwj xeeb yog neutrophils thiab eosinophils).
- Kev kuaj ntshav biochemical - qhov nce ntawm kev ua ntawm daim siab transaminase enzymes (AST, ALT), uas qhia tau tias muaj kev puas tsuaj rau hepatocytes (mob hlwb).
- Ua xua - qhov tshwm tawm ntawm pob khaus ntawm daim tawv nqaij, nws khaus khaus, ua xua (muaj cov yam ntxwv ua pob thiab o uas zoo li muaj cov nettle hlawv). Kev tsis haum tshuaj heev nyob rau hauv daim ntawv ntawm angioedema Quincke edema (kev nrawm rau daim tawv nqaij thiab nqaij hauv lub ntsej muag, qhov chaw mos ntawm sab nraud) yuav tshwm sim tsawg dua. Tau muaj cov neeg paub txog kev txhim kho qhov mob anaphylactic (ib qho kev txo qis tseem ceeb hauv qib ntawm cov ntshav cov ntshav thiab ntau yam hauv lub cev tsis ua haujlwm).
Yog tias muaj kev mob tshwm sim, kev tswj hwm kev daws teeb meem ntawm Gentamicin nres.
Cov lus qhia tshwj xeeb
Ua ntej pib kho nrog Gentamicin Txhaj Tshuaj, cov lus qhia tshwj xeeb yuav tsum raug coj los txiav txim siab txog kev siv, uas suav nrog:
- Cov cim ntawm kev ua haujlwm tsis zoo ntawm lub raum lossis hnov tawm ntawm lub paj hlwb xav kom tsum tsis txhob ua cov tshuaj tam sim ntawd.
- Nrog kev ceev faj, Gentamicin Txhaj tshuaj yog siv rau hauv cov menyuam yaus.
- Yog tias nws yog qhov tsim nyog los tswj cov tshuaj rau tus poj niam cev xeeb tub, tus me nyuam raug hloov mus rau qhov pub mis cuav ntawm qhov sib xyaw cov mis kom haum rau lub sijhawm ntawm kev siv tshuaj Gentamicin.
- Thaum lub sij hawm kho mob nrog cov tshuaj txhaj tshuaj Gentamicin, kev tshuaj xyuas lub sij hawm kuaj ntsuas lub ntsiab biochemical ntawm kev ua haujlwm ntawm lub siab thiab ob lub raum yog qhov yuav tsum tau ua.
- Hauv kev saib xyuas tas mus li, cov tshuaj tau tawm rau cov neeg mob uas lub cev qhuav dej (ua kom lub cev qhuav dej) thiab myasthenia gravis (cov leeg tsis muaj zog).
- Cov tshuaj tuaj yeem cuam tshuam nrog cov tshuaj ntawm lwm pab pawg pharmacological, tshwj xeeb nrog kev sib koom tes ntawm lub voj diuretics (diuretics), nws muaj peev xwm nce nws cov txiaj ntsig tsis zoo rau lub raum.
- Cov tshuaj tsis cuam tshuam rau qhov kev saib xyuas thiab qhov ceev ntawm lub hlwb kev xav.
Hauv cov khw muag tshuaj network, Gentamicin txhaj yog tso los ntawm cov tshuaj noj. Kev ywj siab lossis ntawm kev tawm tswv yim ntawm peb pawg sab nrauv kev siv tshuaj tsis raug pom zoo.