Yuav kho cov ntshav qab zib nrog Humulin NPH li cas?

Kev ncua rau kev txhaj tshuaj (subcutaneously lossis txhaj tshuaj) muaj cov tshuaj insulin rau tib neeg ntawm koob tshuaj 40 lossis 100 IU / ml, muaj nyob hauv 10 ml vials lossis hauv 1.5 thiab 3 ml cartridges rau koob txhaj tshuaj.

Kho kev nqis tes ua: pib - 30 feeb tom qab kev tswj hwm, siab tshaj plaws - nruab nrab ntawm 1 txog 3 teev, sijhawm ntev li 5 txog 7 teev.

Lwm yam tshuaj muaj ib qho kev cov nyom ntau dua.

Piv txwv, Humulin MZ yog kev sib xyaw ntawm ob lub insulins: soluble tib neeg insulin (30%) thiab kev ncua ntawm tib neeg isofan-protamine insulin (70%). Lub npe tag nrho yog insulin biphasic (tib neeg kev tshawb fawb caj ces).

Biphasicity yog vim qhov peculiarity ntawm qhov kev txiav txim ntawm cov tshuaj: thawj cov nyhuv yog txiav txim siab los ntawm qhov kev txiav txim ntawm luv luv ua yeeb yam insulin, uas yog ib feem ntawm nws, ces qhov kev txiav txim ntawm lub sijhawm ntev insulin yog manifested.

Tshaj tawm ntawm kev nqis tes ua tom qab 30 feeb, cov nyhuv siab tshaj plaws tom qab 2-8 teev, lub sijhawm ua haujlwm mus txog 24 teev.

Nws yuav tsum nco ntsoov!

Txhua hom tshuaj ntawm pawg no nyob rau hauv cov khw muag tshuaj muaj npe hauv ampoules lossis vials nrog kua, cov ntawv siv tshuaj hauv daim ntawv ntawm cov ntsiav tshuaj tsis tshwm simKoj tsis tuaj yeem haus lawv. Nws tseem yog ib qho tseem yuav tsum tau ua daim ntawv nqa tshuaj. Cov lus piav qhia tau txuas nrog cov tshuaj, muaj cov lus qhia thiab muab tshuaj rau lub sij hawm noj tshuaj, tab sis ua ntej siv nws yog qhov yuav tsum tau sab laj ib tus kws tshaj lij.

Txoj kev ntawm daim ntawv thov

Humulins raug tswj hwm los ntawm kev hla lub plab zom mov (subcutaneously lossis mob leeg). Raws li txoj cai, tus neeg mob yuav tsum tau mus kawm ib qho kev kawm, piv txwv li, ntawm "cov tsev kawm mob ntshav qab zib." Yuav ua li cas muaj ntau yam ib hnub ib tau txais rau tus neeg mob yog pib txiav txim los ntawm tus kws kho mob.

Qhov ntau npaum li cas ntawm cov tshuaj, xaiv los ntawm tus kws kho mob, tuaj yeem sib txawv raws li hom kev ua si thiab kev noj zaub mov hauv qab tswj hwm ntawm glycemia qib los ntawm tus neeg mob (tab sis kev kawm).
Nws raug nquahu kom siv cov tshuaj kho mob. nruj me ntsis tsis tu ncuaCov. Cov tshuaj siv nrog nrog kev ua haujlwm zoo ib yam, tsis hais tus neeg mob yog tus txiv neej lossis tus poj niam.

Hauv cov menyuam yaus, cov tshuaj no tau pom zoo rau siv. Kev siv kuj yuav tsum tau tswj hwm los ntawm glycemia. Ib qho ntxiv, yog tias muaj hnub nyoog tso cai, menyuam yaus yuav tsum kawm kev cai ntawm lub neej muaj ntshav qab zib.

Rau cov neeg mob laus, yuav tsum tau saib xyuas ntau dua ntawm lub raum kev ua haujlwm, thiab kev noj tshuaj me dua yog siv ntau dua.
Thaum cev xeeb tub, cov tshuaj tau pom zoo rau kev siv.
Humulin tuaj yeem siv rau kev pub niam mis, yog tias lactation tswj tau.

Sab sij huam

Humulin tuaj yeem ua rau lipodystrophy (ntawm qhov chaw txhaj tshuaj), muaj peev xwm tiv thaiv cov tshuaj insulin, kev tsis haum tshuaj, cov poov tshuaj tsawg dua, thiab qhov muag pom tsis pom kev. Cov kev mob tshwm sim (kev fab tshuaj tiv thaiv kab mob) tuaj yeem tsis yog los ntawm insulin nws tus kheej, tab sis los ntawm tus tshaj tawm ntawm cov tshuaj, yog li ntawd, hloov pauv nrog lwm cov tshuaj ntawm insulin raug tso cai.

Kev cuam tshuam nrog lwm yam tshuaj

Lub sijhawm teem ntawm humulin yuav tsum cais xim nrog rau kev siv ua ke nrog cov tshuaj hauv qab no:

Txhim kho cov nyhuv hypoglycemic:

Cov ntsev,
Sulfonamides,
Beta blockers,
Ethanol-muaj npaj
Tshuaj Amp Ntsiav Tshuaj
Cov tshuaj anabolic,
Fibrates
Pentoxifylline
Tetracyclines
Phentolamine,
Cyclophosphamide.

Txo cov nyhuv hypoglycemic:

Qhov ncauj txwv tsis pub muaj
Glucocorticosteroids,
Thiazide diuretics,
Diazoxide
Cov tshuaj tiv thaiv kab mob Tricyclic,
Cov thyroid hormones,
Isoniazid,
Barbiturates
Nicotinic acid
Doxazosin
Glucagon
Kev loj hlob lawm,
Cov neeg sawv cev Symptomimetic.

Tshaj tawm cov tshuaj no yog ua tau, tab sis kev txhaj tshuaj ntawm cov tshuaj humulin yog yuav tsum tau. Feem ntau nws yuav tsum tau siv cov tshuaj humulins thiab tshuaj tua kab mob ua ke nrog cov kabmob sib xyaw ua ke.

Kev noj tshuaj ntau dhau ntawm humulins yog nrog ntshav qab zib nrog, nws yog qhov tshwj xeeb tshaj yog tias noj mov, ua txhaum kev txhaj tshuaj, thiab kev siv lub cev tsis coj mus rau hauv tus lej. Kev quav raws li kev tshawb fawb tsis tau pom.

Tsev muag tshuaj daws teeb meem tshuaj raws li nyob rau hauv daim ntawv qhia.

Lantus thiab Levemir - ncua kev ua yeeb yam insulin

Txog kev kho mob pob qij txha, peb cov neeg nyeem tau siv DiabeNot siv tau zoo. Pom qhov nrov ntawm cov khoom no, peb tau txiav txim siab muab nws rau koj kom txaus siab.

Lantus thiab Levemir yog hom niaj hnub ntawm kev ua yeeb yam ntev ntev, lawv tau txhaj txhua 12-24 teev rau cov ntshav qab zib hom 1 thiab hom 2. Cov insulin nruab nrab hu ua protafan lossis NPH tseem tseem siv. Kev txhaj tshuaj ntawm cov insulin no kav ntev txog 8 teev. Tom qab nyeem tsab xov xwm, koj yuav kawm paub tias txhua hom insulin sib txawv li cas, ib qho twg zoo dua, vim li cas koj yuav tsum txhaj nws.

Qhov kev txiav txim ntawm Lantus, Levemir thiab Protaphane. Cov yam ntxwv ntawm txhua ntawm cov hom tshuaj insulin.
Cov txheej txheem kho rau T1DM thiab T2DM nrog cov tshuaj insulin ntev thiab ceev.
Kev suav ntawm qhov koob tshuaj ntawm Lantus thiab Levemir thaum hmo ntuj: cov lus qhia ib qib zuj zus.
Yuav ua li cas txhaj cov tshuaj insulin thiaj li ua rau cov piam thaj thaum sawv ntxov ntawm lub plab tsis muaj dab tsi li qub.
Hloov los ntawm protafan mus rau niaj hnub txuas ntxiv insulin.
Qhov twg cov insulin zoo dua - Lantus lossis Levemir.
Yuav ua li cas xaiv cov koob tshuaj thaum sawv ntxov ntawm cov tshuaj insulin txuas ntxiv.
Kev noj zaub mov kom txo tau cov tshuaj insulin los ntawm 2-7 zaug thiab tshem tawm cov ntshav qab zib kom zoo.

Peb tseem muab txoj hauv kev thiab txoj hauv kev zoo rau kev ua haujlwm kom paub tseeb tias koj cov piam thaj hauv ntshav tsis muaj dab tsi li qub thaum sawv ntxov.

Cov neeg mob ntshav qab zib yuav tsum tau txhaj tshuaj ntxiv insulin thaum hmo ntuj thiab / lossis thaum sawv ntxov, tsis hais tus neeg mob tau txhaj tshuaj insulin sai ua ntej noj mov. Qee tus neeg mob ntshav qab zib tsuas xav tau kev kho mob nrog tshuaj insulin txuas ntxiv. Lwm tus tsis xav tau cov tshuaj insulin txuas ntxiv, tab sis lawv txhaj cov insulin luv luv lossis luv-luv rau kom tua tau cov ntshav kom ntshav zoo tom qab noj mov. Tseem muaj dua lwm tus neeg xav tau ob qho los tswj kev noj qab zib ib txwm, lossis teeb meem ntshav qab zib yuav tshwm sim.

Txhawm rau xaiv cov tshuaj insulin, kev noj tshuaj thiab cov sij hawm txhaj tshuaj rau tus neeg mob ntshav qab zib tus kheej hu ua "teeb tsa tshuaj insulin kho". Cov txheej txheem no raug suav ua raws li kev soj ntsuam tag nrho cov ntshav qab zib kom tswj tau li ntawm 1-3 lub lis piam. Ua ntej tshaj plaws, koj yuav tsum tshawb nrhiav seb cov ntshav qab zib hauv tus neeg mob yuav coj txawv li cas ntawm cov sij hawm ntawm hnub tawm tsam cov tom qab ntawm cov zaub mov tsis muaj piam thaj ntau. Tom qab ntawd, nws thiaj pom tseeb tias kev kho tshuaj insulin nws xav tau dab tsi. Nyeem cov lus “Dab tsi yuav insulin los txhaj, lub sijhawm thiab sijhawm twg. Tus qauv rau ntshav qab zib hom 1 thiab ntshav qab zib hom 2. "

Kev siv tshuaj insulin ntxiv tsis tas yuav tsum tau ua, tab sis yuav tsum tau txhaj tshuaj insulin sai ua ntej noj mov. Los yog hloov ua lwm yam - koj xav tau txuas ntxiv insulin rau yav hmo ntuj, thiab yav tav su tom qab noj qab zib yog qhov qub. Lossis tus neeg mob ntshav qab zib yuav pom qee qhov lwm tus neeg. Xaus: yog tias tus kws kho mob endocrinologist tau sau ntawv kho tib yam rau txhua tus neeg mob ntawm kev txhaj tshuaj ntawm cov tshuaj insulin thiab tsis saib cov txiaj ntsig ntawm lawv cov ntshav qab zib ntsuas, ces nws yog qhov zoo dua rau lwm tus kws kho mob tham.

Vim li cas thiaj yuav tsum muaj insulin ntev

Xav ntev ntev cov insulin Lantus, Levemir lossis Protafan xav tau txhawm rau tswj cov piam thaj sai. Ib qho me me ntawm cov insulin kis rau hauv tib neeg cov ntshav txhua lub sijhawm. Qhov no yog hu ua keeb kwm yav dhau los (theem pib) ntawm insulin. Qhov ua tiav ntawm cov voos insulin txuas ntxiv, 24 teev nyob rau ib hnub. Tsis tas li ntawd, nyob rau hauv kev teb rau ib pluas noj, nws tseem ntxiv pov ntau ntawm cov feem ntau ntawm cov tshuaj insulin rau hauv cov ntshav. Qhov no hu ua bolus koob tshuaj lossis bolus.

Boluses nce insulin concentration rau lub sijhawm luv luv. Qhov no ua rau nws muaj peev xwm tua cov piam thaj kom sai sai uas tau tshwm sim vim yog cov khoom noj los ntawm cov khoom noj. Hauv cov neeg mob uas muaj ntshav qab zib hom 1, tus txiav ua tsis tiav cov tshuaj insulin basal lossis bolus. Cov tshuaj insulin ntev ntev muab cov tshuaj insulin tom qab, qhov qis ntawm cov tshuaj insulin.Nws yog ib qho tseem ceeb uas lub cev tsis "zom" nws cov protein thiab tsis tshwm sim ketoacidosis uas muaj ntshav qab zib.

Lwm lub hom phiaj ntawm kev kho mob ntshav qab zib nrog cov insulin ntev mus yog tiv thaiv kev tuag ntawm qee cov kab mob pancreatic beta hlwb. Kev hno ntawm Lantus, Levemir lossis Protafan txo qis kev thauj ntawm lub txiav. Vim tias qhov no, tsawg dua cov qe hlwb tuag, ntau dua ntawm lawv tseem muaj sia nyob. Txhaj tshuaj ntxiv ntawm cov insulin thaum hmo ntuj thiab / lossis thaum sawv ntxov yuav muaj feem ntau uas cov ntshav qab zib hom 2 yuav tsis nkag mus rau tus mob ntshav qab zib hom 1 loj dua. Txawm hais tias rau cov neeg mob uas muaj ntshav qab zib hom 1, yog tias ib feem ntawm cov qe ntshav tuaj yeem khaws cia kom ciaj sia, chav kawm ntawm tus kab mob txhim kho. Qab zib tsis hla, ua stably nyob ze rau ib txwm.

Cov insulin ntev ntev tau siv rau lub hom phiaj sib txawv dua li kev siv lub tshuab insulin ua ntej noj mov. Nws tsis yog npaj ua rau ziab kom cov ntshav qab zib kom muaj ntshav spikes tom qab noj mov. Thiab, nws yuav tsum tsis txhob siv kom sai qab zib cov piam thaj yog tias nws cia li nce hauv koj siab. Vim tias ntev insulin kuj qeeb dhau rau qhov ntawd. Txhawm rau nqus cov zaub mov uas koj noj, siv cov insulin luv luv lossis ultra-luv. Tib yam mus rau sai sai nqa cov piam thaj kom siab.

Yog tias koj sim ua dab tsi txuas ntxiv ntawm cov insulin yog rau ncua sij hawm nrog insulin, qhov tshwm sim ntawm kev kho mob ntshav qab zib yuav ua rau neeg txom nyem heev. Tus neeg mob yuav muaj kev nce ntxiv hauv cov ntshav qab zib, uas ua rau mob nkees ntev thiab mob ntshav siab. Hauv ob peb xyoos, cov teeb meem loj yuav tshwm sim uas yuav ua rau tus neeg xiam oob khab.

Dab tsi yog qhov sib txawv ntawm Lantus molecule thiab insulin tib neeg

Insulin Lantus (Glargin) yog tsim tawm los ntawm kev siv cov khoom siv tshuaj tua hluav taws xob. Nws tau los ntawm kev rov ua kom tiav ntawm Escherichia coli Escherichia coli kab mob DNA (K12 hom). Hauv cov tshuaj insulin molecule, Glargin hloov asparagine nrog glycine ntawm txoj haujlwm 21 ntawm txoj saw A, thiab ob lub lwg ntawm arginine ntawm txoj haujlwm 30 ntawm cov saw B tau ntxiv. Qhov sib ntxiv ntawm ob lub arginine lwg me me rau C-terminus ntawm B-saw hloov pauv isoelectric kis los ntawm pH 5.4 rau 6.7.

Lantus insulin molecule - ua kom yooj yim dua nrog me ntsis acidic pH. Nyob rau tib lub sijhawm, nws yog qhov tsawg dua li ntawm tib neeg cov tshuaj insulin, soluble ntawm physiological pH ntawm subcutaneous ntaub so ntswg. Hloov A21 asparagine nrog glycine yog isoelectrically nruab nrab. Nws yog tsim los muab cov txiaj ntsig kev tshwm sim ntawm tib neeg insulin nrog kev ruaj khov. Insulin Glargin yog tsim nyob rau ntawm pH acidic ntawm 4.0, thiab yog li ntawd nws yog txwv tsis pub sib xyaw nrog insulin tsim ntawm qhov nruab nrab pH, thiab tseem mus rau nws cov dej qab ntsev lossis dej haus.

Insulin Lantus (Glargin) muaj lub caij nyoog ntev vim qhov tseeb tias nws muaj tus nqi tshwj xeeb qis pH. Ib qho pauv pH ua rau qhov tseeb tias hom insulin yaj tsawg dua ntawm cov physiological pH ntawm cov nqaij mos subcutaneous. Lantus (Glargin) yog cov tshuaj ntshiab, ntshiab. Tom qab subcutaneous tswj hwm cov kua dej, nws tsim cov microrecipients nyob rau hauv nruab nrab lub cev muaj sia pH ntawm qhov chaw subcutaneous. Insulin Lantus yuav tsum tsis txhob tov nrog dej qab ntsev lossis dej rau kev txhaj tshuaj, vim tias vim qhov no, nws tus pH yuav mus rau qhov qub, thiab lub tshuab ntawm kev ua haujlwm ntev ntawm insulin yuav cuam tshuam. Qhov zoo ntawm Levemir yog tias nws zoo li yuav tsum tau diluted li sai tau, txawm hais tias qhov no tsis tau tso cai pom zoo, nyeem ntxiv rau hauv qab no.

Nta ntawm lub caij nyoog ntev insulin Levemir (Detemir)

Insulin Levemir (Detemir) yog lwm qhov ntawm cov insulin ntev, uas yog kev sib tw rau Lantus, uas tau tsim los ntawm Novo Nordisk. Piv rau tib neeg cov kua dej, cov amino acid nyob hauv Levemir molecule raug tshem tawm ntawm txoj haujlwm 30 ntawm txoj saw B. Hloov chaw, qhov seem ntawm cov roj fatty acid, myristic acid, uas muaj 14 cov pa roj carbon atoms, txuas rau cov amino acid lysine ntawm txoj haujlwm 29 ntawm B txoj saw. Vim qhov no, 98-99% ntawm cov tshuaj insulin Levemir hauv cov ntshav tom qab txhaj khi rau albumin.

Levemir yog maj mam nqus los ntawm thaj chaw txhaj tshuaj thiab muaj lub sijhawm ntev. Nws qhov ua kom qeeb yog ua tiav vim qhov tseeb tias cov tshuaj insulin nkag mus rau hauv cov hlab ntshav qeeb dua, thiab kuj vim tias cov lwg me me ntawm insulin analogue nkag mus rau cov phiaj hlwb qeeb qeeb. Txij li hom insulin no tsis muaj qhov tshaj tawm ntawm lub luag haujlwm, qhov kev pheej hmoo ntawm ntshav qog ntshav qis yog txo los ntawm 69%, thiab hmo ntuj hypoglycemia - los ntawm 46%. Qhov no tau qhia los ntawm kev tshawb pom 2 xyoo hauv cov neeg mob ntshav qab zib hom 1.

Qhov twg ntev insulin yog qhov zoo dua - Lantus lossis Levemir?

Lantus thiab Levemir yog qhov ua yeeb yam ntev ntev rau cov tshuaj insulin, qhov tseeb tshaj plaws hauv kev kho mob ntshav qab zib nrog cov tshuaj insulin. Lawv muaj txiaj ntsig zoo nyob rau hauv tias lawv muaj cov haujlwm ruaj khov yam tsis muaj qhov siab tshaj - cov ntshav plasma concentration daim duab ntawm cov hom insulin muaj hom "dav hlau nthwv dej". Nws luam tawm qhov ib txwm muaj sia hauv kev sib xyaw ntawm basal (keeb kwm yav dhau) insulin.

Lantus thiab Detemir yog hom ruaj khov thiab kwv yees li ntawm hom tshuaj insulin. Lawv coj yuav luag tus kheej hauv cov neeg mob sib txawv, nrog rau hnub sib txawv ntawm tib tus neeg mob. Tam sim no ib tus kws kho ntshav qab zib tsis tas yuav sib tov txhua yam ua ntej muab nws tus kheej txhaj tshuaj tiv thaiv kab mob ntev npaum li cas, thiab ua ntej tias muaj ntau dua fuss nrog “nruab nrab” insulin protafan.

Ntawm Lub Pob Lantus nws tau sau tseg tias txhua qhov insulin yuav tsum siv nyob rau hauv 4 lub lis piam lossis 30 hnub tom qab cov ntawv tau luam tawm. Levemir muaj lub txee kev ua haujlwm ntawm 1.5 lub sijhawm ntev dua, mus txog 6 lub limtiam, thiab tsis raug cai mus txog 8 lub limtiam. Yog tias koj ua raws li cov zaub mov tsis muaj carbohydrate rau cov ntshav qab zib hom 1 lossis hom 2, koj yuav xav tau koob tshuaj insulin tsawg kawg txhua hnub. Yog li no, Levemir yuav yooj yim dua.

Kuj tseem muaj cov lus qhia (tsis yog qhov tseeb!) Tias Lantus ua rau muaj kev pheej hmoo ntawm mob qog nqaij hlav ntau dua li lwm hom insulin. Qhov laj thawj muaj peev xwm yog tias Lantus muaj qhov kev sib txuam siab rau kev loj hlob hormone receptors uas nyob rau saum npoo ntawm cov qog nqaij hlav cancer. Cov ntaub ntawv hais txog Lantus kev koom tes hauv kev mob qog noj ntshav tsis tau muaj pov thawj, cov kev tshawb fawb tshawb pom yog qhov sib txawv. Tab sis nyob rau hauv txhua rooj plaub, Levemir yog qhov pheej yig dua thiab hauv kev coj ua tsis muaj qhov phem dua. Qhov txiaj ntsig tseem ceeb yog tias Lantus yuav tsum tsis txhob xeb txhua, thiab Levemir - yog tias ua tau, txawm tias tsis raws cai. Tsis tas li, tom qab pib siv, Levemir khaws cia ntev dua li Lantus.

Coob tus neeg mob ntshav qab zib thiab endocrinologist ntseeg tias yog tias txhaj ntau dua, yog li txhaj ib koob Lantus ib hnub yog qhov txaus. Nyob rau hauv txhua kis, levemir yuav tsum tau txhaj ob zaug ib hnub, thiab yog li ntawd, nrog cov koob tshuaj loj loj, nws yooj yim dua yog qhov raug kho nrog Lantus. Tab sis yog tias koj tab tom siv hom kev kho mob ntshav qab zib hom 1 los yog hom kho mob ntshav qab zib hom 2, cov kev txuas rau uas tau muab hauv qab no, tom qab ntawd koj yuav tsis xav tau qhov kev ncua tshuaj ntau ntxiv ntawm cov tshuaj insulin txhua lub sijhawm. Peb xyaum tsis siv cov koob tshuaj loj no uas lawv txuas ntxiv ua haujlwm ib hnub nkaus, tsuas yog cov neeg mob ntshav qab zib hom 2 uas muaj rog rog ntau dhau. Vim tias tsuas yog tus txheej txheem ntawm cov khoom thauj me me tso cai rau koj kom ua tiav kev tswj hwm ntshav qab zib hauv hom 1 thiab ntshav qab zib hom 2.

Peb tswj cov ntshav qab zib ntawm 4.6 ± 0.6 mmol / L, zoo li cov neeg noj qab haus huv, 24 teev nyob rau ib hnub, nrog kev hloov pauv me ntsis ua ntej thiab tom qab noj mov. Txhawm rau kom ua tiav lub hom phiaj no, koj yuav tsum tau txhaj tshuaj ntxiv nyob rau hauv cov koob tshuaj me ob zaug ib hnub. Yog hais tias mob ntshav qab zib tau kho nrog kev txhaj tshuaj me me ntawm kev tiv thaiv kab mob ntev, tom qab lub sijhawm ntawm Lantus thiab Levemir yuav luag zoo li qub. Nyob rau tib lub sijhawm, qhov zoo ntawm Levemir, uas peb tau piav qhia saum toj no, yuav tshwm sim lawv tus kheej.

Yuav kho li cas rau hom ntshav qab zib 2: txheej txheem ib qib zuj zus
Cov tshuaj ntshav qab zib hom 2: cov ncauj lus kom ntxaws
Siofor thiab Glucofage ntsiav tshuaj
Li cas los kawm kom txaus siab rau kev kawm siv lub cev

Hom 1 kho mob ntshav qab zib rau cov neeg laus thiab menyuam
Honeymoon lub sijhawm thiab yuav ua li cas txuas ntxiv nws
Cov txheej txheem ntawm kev siv tshuaj insulin tsis muaj mob
Mob ntshav qab zib Hom 1 rau menyuam yaus raug kho yam tsis raug siv tshuaj noj kom yog. Xam phaj nrog tsev neeg.
Yuav ua li cas qeeb ntawm kev ua haujlwm ntawm lub raum

Vim li cas nws yog qhov tsis tsim nyog siv NPH-insulin (protafan)

Txog rau lub sijhawm xyoo 1990, cov hom tshuaj insulin luv luv tau huv raws li dej, thiab txhua tus so tau huab, opaque. Cov tshuaj insulin yuav dhau los vim muaj qhov sib ntxiv ntawm cov khoom siv uas ua rau cov lus tshwj xeeb uas maj mam yaj hauv qab daim tawv nqaij ntawm ib tug neeg. Txog rau hnub no, tsuas yog ib hom tshuaj insulin tau nyob twj ywm raws caij nyoog - nruab nrab ncua sijhawm ntawm kev nqis tes, uas hu ua NPH-insulin, tseem hu ua protafan. NPH sawv cev rau "Hagedorn's Neutral Protamine," uas yog protein ntawm cov tsiaj keeb kwm.

Hmoov tsis zoo, NPH-insulin tuaj yeem txhawb lub zog tiv thaiv kab mob los tsim cov tshuaj tiv thaiv rau cov tshuaj insulin. Cov tshuaj tua kab mob no tsis ua kom puas, tab sis khi ib ntus ntawm cov insulin thiab ua rau nws tsis voos. Tom qab ntawd qhov kev khi no cov kab mob dheev dhau los ua neeg nquag thaum nws tsis xav tau ntxiv lawm. Cov nyhuv no yog heev zog. Rau cov ntshav qab zib zoo tib yam, qhov sib txawv ntawm cov piam thaj ntawm ± 2-3 mmol / L yog qhov kev txhawj xeeb me ntsis, thiab lawv tsis pom nws. Peb sim tswj kev ua kom zoo rau cov ntshav qab zib, xws li 4.6 ± 0.6 mmol / l ua ntej thiab tom qab noj mov. Txhawm rau ua qhov no, peb ua txoj haujlwm kho mob ntshav qab zib hom 1 lossis hom kho ntshav qab zib hom 2. Hauv peb qhov xwm txheej, qhov tsis txaus ntseeg ntawm kev sib txuas nruab nrab insulin yuav pom tau thiab lwj daim duab.

Muaj lwm qhov teeb meem nrog tus neeg nruab nrab tiv thaiv Hagedorn. Angiography yog kev soj ntsuam ntawm cov hlab ntshav uas pub lub siab kom pom tias lawv muaj kev cuam tshuam li cas los ntawm atherosclerosis. Nov yog ib qho kev siv tshuaj los khomob. Ua ntej ua nws, tus neeg mob tau raug txhaj tshuaj ntawm heparin. Qhov no yog ib qho anticoagulant uas tiv thaiv platelets los txhaws ua ke thiab thaiv cov hlab ntsha nrog cov ntshav cov ntshav. Tom qab cov txheej txheem tiav, ua ib qho kev txhaj tshuaj ntxiv - NPH raug tswj hwm "thim tawm" heparin. Hauv feem pua me me ntawm cov tib neeg uas tau raug kho nrog protafan insulin, kev tsis haum tshuaj muaj tshwm sim nyob rau tam sim no, uas tuaj yeem ua rau tuag taus.

Qhov xaus yog tias yog tias nws tuaj yeem siv qee lwm yam hloov ntawm NPH-insulin, ces nws yog qhov zoo dua los ua qhov no. Raws li txoj cai, cov mob ntshav qab zib tau hloov pauv los ntawm NPH-insulin mus rau kev ua yeeb yam txuas ntxiv insulin analogues Levemir lossis Lantus. Ntxiv mus, lawv tseem qhia pom tias muaj txiaj ntsig zoo tshaj plaws ntawm kev tswj ntshav qab zib.

Qhov tsuas yog qhov kev siv ntawm NPH-insulin tseem tsim nyog niaj hnub no nyob hauv Asmeskas (!) Cov menyuam me uas muaj ntshav qab zib hom 1. Lawv xav tau cov tshuaj insulin tsawg kawg ntawm kev kho mob. Cov koob tshuaj no yog ib qho me me uas yuav tsum muaj cov tshuaj insulin. Hauv tebchaws United States, qhov no yog ua tiav siv cov peev txheej insulin dilution dlaws muab los ntawm cov tuam ntxhab dawb. Txawm li cas los xij, rau insulin analogues ntawm lub sijhawm ua haujlwm ntev, xws li kev daws teeb meem tsis muaj. Yog li no, Dr. Bernstein raug yuam kom sau ntawv txhaj tshuaj ntawm NPH-insulin, uas tuaj yeem raug 3-4 zaug ib hnub, rau nws cov neeg mob hluas.

Hauv cov teb chaws hais lus Lavxias, hom kev daws teeb meem rau insulin dilution tsis muaj nyob rau nruab hnub nrog hluav taws, rau ib qho nyiaj, txhua qhov ntau ntxiv pub dawb. Yog li, tib neeg txhaws insulin los ntawm kev yuav khoom saline lossis dej rau kev txhaj tshuaj hauv cov khw muag tshuaj. Thiab nws zoo li tias txoj kev no ntau dua lossis tsawg dua ua haujlwm, txiav txim los ntawm kev txheeb xyuas cov ntsiab lus ntshav qab zib. Nyob rau hauv txoj kev no, Levemir (tab sis tsis yog Lantus!) Txuas ntxiv insulin yog diluted. Yog tias koj siv NPH-insulin rau tus menyuam, tom qab ntawd koj yuav tsum txhaws nws nrog cov kua ntsev tib yam li Levemir. Nws yuav tsum tau yug los hauv lub siab tias Levemir ua tau zoo dua thiab nws tsis tsim nyog los laim nws. Nyeem ntxiv hauv kab lus “Yuav ua li cas txhawm rau tshuaj insulin kom raug txhaj tshuaj qis”

Yuav ua li cas ua kom qab zib rau yav sawv ntxov ntawm lub plab khoob yuav li qub

Piv txwv tias koj tab tom noj ntau tshaj plaws cov tshuaj kom zoo rau hom 2 ntshav qab zib thaum hmo ntuj.Dua li ntawm qhov no, koj cov ntshav qab zib thaum sawv ntxov nyob ntawm lub plab khoob yog qhov siab dua li ib txwm, thiab nws feem ntau nce ib hmos. Qhov no txhais tau tias koj yuav tsum tau txhaj tshuaj txuas ntxiv thaum hmo ntuj. Txawm li cas los xij, ua ntej sau ntawv txhaj tshuaj li no, koj yuav tsum paub tseeb tias cov ntshav qab zib tau noj hmo 5 teev ua ntej mus pw. Yog tias cov piam thaj hauv ntshav nce siab thaum hmo ntuj vim qhov tseeb hais tias tus neeg mob ntshav qab zib muaj noj hmo lig, tom qab ntawd txuas insulin thaum tsaus ntuj yuav tsis pab. Nco ntsoov tias txoj kev noj qab haus huv zoo rau kev noj hmo kom ntxov. Ua ib qho kev ceeb toom ntawm koj lub xov tooj ntawm tes thaum 5.30 teev tsaus ntuj tias nws yog sijhawm los noj hmo, thiab muaj noj hmo thaum 6 teev tsaus ntuj-6.30 p.m. Tom qab noj hmo tag rau hnub tom qab, koj yuav zoo siab noj zaub mov protein rau pluas tshais.

Cov hom tshuaj insulin txuas ntxiv yog Lantus thiab Levemir. Saum toj no hauv tsab xov xwm no peb tau tham hauv kev nthuav dav seb lawv sib txawv li cas thiab ib qho twg zoo siv. Cia peb pom tias kev txhaj tshuaj txuas ntxiv li cas thaum hmo ntuj ua haujlwm. Koj yuav tsum paub tias daim siab yog ua haujlwm tshwj xeeb hauv kev ua kom muaj cov tshuaj insulin thaum sawv ntxov, ua ntej yuav sawv. Qhov no hu ua thaum sawv ntxov kaj ntug. Nws yog nws leej twg ua rau muaj ntshav qab zib cov ntshav thaum sawv ntxov ntawm lub plab khoob. Tsis muaj leej twg paub txog nws cov laj thawj. Txawm li cas los xij, nws tuaj yeem tswj tau zoo yog tias koj xav ua kom tau qab zib li qub thaum sawv ntxov ntawm lub plab khoob. Nyeem ntxiv hauv kev nthuav dav "Phenomenon ntawm Tag kis Sawv ntxov thiab Yuav Tswj Nws Li Cas."

Vim tias qhov tshwm sim thaum sawv ntxov ntxov, qhov txhaj tshuaj insulin ntev dua thaum hmo ntuj pom zoo kom tsis pub dhau 8,5 teev ua ntej koj sawv thaum sawv ntxov. Cov txiaj ntsig ntawm kev txhaj tshuaj ntawm cov tshuaj insulin ntev ntev thaum hmo ntuj tau qaug zog heev 9 teev tom qab txhaj tshuaj. Yog tias koj ua raws li cov zaub mov tsis muaj carbohydrate rau cov ntshav qab zib, tom qab ntawd txhua yam tshuaj insulin, suav nrog insulin txuas ntxiv thaum hmo ntuj, yuav tsum muaj tsawg. Hauv cov xwm txheej zoo li no, feem ntau muaj txiaj ntsig ntawm kev txhaj tshuaj yav tsaus ntuj ntawm Levemir lossis Lantus nres ua ntej tsaus ntuj. Txawm hais tias cov tuam ntxhab hais tias qhov kev txiav txim ntawm cov hom insulin no kav ntev dua.

Yog tias koj qhov txhaj tshuaj thaum tsaus ntuj ntawm cov tshuaj insulin mus txuas ntxiv ua haujlwm txhua hmo thiab txawm tias sawv ntxov, tom qab ntawd koj tau txhaj ntau dua, thiab thaum ib tag hmo cov suab thaj yuav poob qis dua qhov qub. Ntawm qhov zoo tshaj plaws, yuav muaj kev npau suav phem, thiab ntawm qhov phem tshaj, muaj ntshav qab zib ntau. Koj yuav tsum teeb tsa lub tswb ntsig kom sawv tom qab 4 teev, thaum ib tag hmo, thiab ntsuas koj cov ntshav qab zib nrog ib glucometer. Yog tias nws qis dua 3.5 mmol / L, tom qab ntawd faib cov koob tshuaj ncua sij hawm yav tsaus ntuj rau hauv ob ntu. Caw ib qho ntawm cov seem tsis sai, tab sis tom qab 4 teev.

Peb taw qhia ib zaug ntxiv: yog tias cov koob tshuaj ntev ntawm cov insulin ntau dua nyob rau hmo ntuj, tom qab ntawd yoo cov piam thaj yuav tsis poob rau tag kis sawv ntxov, tab sis nce ntxiv.

Txhawm rau faib cov koob tshuaj yav tsaus ntuj ntawm cov tshuaj insulin txuas ua ob ntu, ib qho ntawm cov neeg tau hno hauv nruab nrab ntawm qhov tsaus ntuj, yog qhov tseeb heev. Nrog rau cov kev cai no, tag nrho cov koob tshuaj thaum yav tsaus ntuj ntawm cov tshuaj insulin tuaj yeem txo los ntawm 10-15%. Nws kuj tseem yog txoj hauv kev zoo tshaj plaws los tswj thaum sawv ntxov thaum sawv ntxov thiab muaj ntshav qab zib ib txwm nyob rau yav sawv ntxov ntawm lub plab khoob. Kev txhaj tshuaj rau hmo ntuj yuav ua rau muaj qhov tsawg kawg ntawm kev tsis xis nyob thaum koj tau siv nrog lawv. Nyeem yuav ua li cas tau txhaj tshuaj insulin. Thaum ib tag hmo, koj tuaj yeem hno cov koob tshuaj txuas ntxiv hauv qhov tsis hnov qab yog tias koj npaj txhua yam rau nws thaum yav tsaus ntuj thiab tom qab ntawd tam sim ntawd tsaug zog dua.

Kev kho mob ntshav qab zib nrog insulin: pib ntawm no. Hom insulin thiab txoj cai rau nws cov khoom cia.
Yuav siv hom tshuaj insulin dab tsi rau kev txhaj tshuaj, sijhawm lub sijhawm twg thiab siv sijhawm twg. Cov txheej txheem rau hom ntshav qab zib hom 1 thiab ntshav qab zib hom 2.
Cov tshuaj insulin cov koob txhaj tshuaj, koob txhaj tshuaj thiab koob rau lawv. Cov koob txhaj tshuaj twg zoo siv.
Ultrashort insulin Humalog, NovoRapid thiab Apidra. Tib neeg luv insulin
Muab xam los ntawm cov koob tshuaj insulin ua ntej noj mov. Yuav ua li cas kom qis qab zib rau li qub yog tias nws dhia
Yuav ua li cas txhawm rau cov tshuaj insulin kom raug txhaj tshuaj qis
Kev kho mob rau cov menyuam yaus uas muaj hom 1 ntshav qab zib diluted insulin Humalog (Kev paub txog Polish)
Insulin twj tso kua mis: pros thiab cons. Tso kua mis kho

Yuav ua li cas los laij cov pib txhaj tshuaj ncua sij hawm thaum tsaus ntuj

Peb lub hom phiaj kawg yog kom xaiv cov koob tshuaj xws li Lantus, Levemir, lossis Protafan kom cov khoom qab zib sai sai yog nyob rau ntawm 4.6 ± 0.6 mmol / L. Nws yog qhov tshwj xeeb tshaj yog nyuaj rau normalize qab zib thaum sawv ntxov ntawm lub plab khoob, tab sis cov teeb meem no tseem daws tau yog tias koj sim. Yuav daws nws li tau piav qhia saum toj no.

Txhua tus neeg mob uas muaj ntshav qab zib hom 1 xav tau cov tshuaj insulin txuas ntxiv thaum hmo ntuj thiab yav sawv ntxov, nrog rau kev txhaj tshuaj sai sai ua ntej noj mov. Nws hloov tawm 5-6 zaug ib hnub twg. Hauv cov neeg mob uas muaj ntshav qab zib hom 2, cov xwm txheej yooj yim dua. Tej zaum lawv yuav tsum tau txhaj tshuaj tsawg dua. Tshwj xeeb tshaj yog yog hais tias tus neeg mob ua raws kev noj haus nrog cov zaub mov uas tsis muaj carbohydrate thiab tsis tub nkeeg kom ua si nrog kev lom zem. Cov neeg muaj ntshav qab zib hom 1 tseem qhia kom hloov mus rau qhov kev noj haus cov zaub mov kom qis. Yog tsis muaj qhov no, koj yuav tsis tuaj yeem tswj hwm cov piam thaj kom zoo, txawm hais tias koj ua tib zoo suav cov tshuaj insulin ntau npaum li cas.

Ua ntej tshaj plaws, peb ntsuas ntsuas qab zib nrog glucometer 10-12 zaug hauv ib hnub rau 3-7 hnub kom nkag siab tias nws coj li cas. Qhov no yuav qhia peb txog lub sijhawm koj xav tau txhaj insulin. Yog tias txoj haujlwm ntawm cov roj ntsha beta ntawm cov txiav ua tiav nrog qee cov khaws cia, ces tej zaum nws yuav muaj peev xwm mus txhaj nws tsuas yog thaum hmo ntuj lossis qee lub sijhawm noj mov. Yog tias tus neeg mob uas muaj ntshav qab zib hom 2 xav tau kev txhaj tshuaj ntawm cov tshuaj insulin ntev, ces ua ntej ntawm tag nrho cov Lantus, Levemir lossis Protafan yuav tsum tau txhaj tshuaj thaum hmo ntuj. Puas yog hais tias xav kom txhaj tshuaj insulin ntev zog thaum sawv ntxov? Nws yog nyob ntawm qhov ntsuas ntawm 'meter'. Tshawb nrhiav kom koj cov piam thaj qab zib li cas ib hnub.

Ua ntej, peb suav qhov pib pib ntawm kev insulin txuas ntxiv, thiab tom qab ntawd hnub tom ntej peb hloov kho nws kom txog thaum qhov txiaj ntsig tau txais

Hauv 7 hnub, peb ntsuas ntshav qab zib nrog ib qho glucometer thaum hmo ntuj, thiab tom qab ntawd tag kis sawv ntxov ntawm lub plab khoob.
Cov txiaj ntsig tau raug sau cia hauv lub rooj.
Peb suav rau txhua hnub: qab zib thaum sawv ntxov nyob ntawm lub plab tsis hnov qab rho tawm suab thaj nag hmo.
Peb muab pov tseg hnub uas cov kws kho ntshav qab zib tau noj hmo ua ntej 4-5 teev ua ntej yuav mus pw.
Peb pom qhov tsawg kawg nkaus tus nqi ntawm qhov nce no rau lub sijhawm soj.
Phau ntawv qhia yuav pom tias 1 UNIT ntawm insulin txo cov ntshav qab zib li cas. Qhov no hu ua qhov zoo tshaj yuav tso cov tshuaj insulin.
Faib cov khoom qab zib kom tsawg kawg nkaus hauv ib hmo los ntawm kwv yees qhov sib npaug ntawm kev nkag siab zoo rau insulin. Qhov no muab qhov pib rau peb.
Nyas rau yav tsaus ntuj qhov kev suav tshuaj ntawm cov sij hawm txuas ntxiv. Peb teeb tsa lub tswb kom tsa thaum ib tag hmo thiab tshawb xyuas qab zib.
Yog tias muaj piam thaj thaum tsaus ntuj qis dua 3.5-3.8 mmol / L, qhov koob tshuaj yav tsaus ntuj yuav tsum tau qis. Cov qauv pab - hloov chaw ntawm nws mus rau kev txhaj tshuaj ntxiv ntawm 1-3 teev sawv ntxov.
Hauv ob peb hnub tom qab no, peb nce los yog txo qhov hno, sim ntau cov kev xav, kom txog rau thaum sawv ntxov cov ntshav qab zib nyob rau hauv ib txwm li ntawm 4.6 ± 0.6 mmol / L, ib txwm tsis muaj hmo ntuj hypoglycemia.

Cov ntaub ntawv piv txwv rau xam qhov pib siv ntawm Lantus, Levemir lossis Protafan thaum tsaus ntuj

Txog kev kho mob pob qij txha, peb cov neeg nyeem tau siv DiabeNot siv tau zoo. Pom qhov nrov ntawm cov khoom no, peb tau txiav txim siab muab nws rau koj kom txaus siab.

Hnub Tuesday Hnub Wednesday Plaub Hnub Friday Hnub Saturday Hnub Sunday Hnub Monday

Peb pom tias cov ntaub ntawv rau hnub Thursday yuav tsum tau muab pov tseg, vim hais tias tus neeg mob tau noj hmo tas li. Hnub so, hnub qab zib nce qib tsawg kawg yog tsaus ntuj hnub Friday. Nws ntau txog 4.0 mmol / L. Peb coj txoj kev loj hlob yam tsawg kawg nkaus, thiab tsis yog qhov siab tshaj plaws lossis txawm qhov nruab nrab. Lub hom phiaj yog kom tau txais cov tshuaj insulin pib qis dua es tsis txhob siab. Qhov no ntxiv kev pov hwm tus neeg mob tawm tsam nocturnal hypoglycemia. Cov kauj ruam tom ntej yog kom pom cov kwv yees qhov sib npaug ntawm kev nkag siab zoo rau insulin los ntawm cov nqi ntawm lub rooj.

Piv txwv nyob rau hauv tus neeg mob uas muaj ntshav qab zib hom 1, tus txiav ua kom tiav tsis tsim nws cov tshuaj insulin. Hauv qhov no, 1 ntu ntawm cov tshuaj insulin txuas ntxiv yuav txo cov ntshav qab zib kom tsawg li 2.2 mmol / L hauv ib tus neeg hnyav 64 kg. Qhov ntau koj hnyav, qhov ua kom qaug zog ntawm cov tshuaj insulin.Piv txwv li, rau tus neeg hnyav 80 kg, 2.2 mmol / L * 64 kg / 80 kg = 1.76 mmol / L yuav tau txais. Peb daws cov teeb meem los ntawm kev suav qhov feem ntawm qhov kawm hauv tsev kawm theem pib laij zauv.

Rau cov neeg mob uas muaj ntshav qab zib hom 1 loj tshaj plaws, peb coj tus nqi no ncaj qha. Tab sis rau cov neeg mob uas muaj ntshav qab zib hom 2 lossis hom ntshav qab zib hom 1 hauv daim ntawv me, nws yuav dhau siab. Piv txwv koj tus txiav ua qab zib tseem ua kua dej insulin. Txhawm rau tshem tawm qhov kev pheej hmoo ntawm hypoglycemia, peb yuav xub xav txog "nrog cov npoo" uas 1 ntu ntawm cov insulin txo qis cov ntshav qab zib kom ntau li 4.4 mmol / l thiab hnyav 64 kg. Koj yuav tsum txiav txim siab tus nqi no rau koj qhov hnyav. Ua ib qho kev faib ua feem, xws li ua piv txwv saum toj no. Rau tus menyuam uas hnyav 48 kg, 4.4 mmol / L * 64 kg / 48 kg = 5.9 mmol / L yuav tau txais. Rau cov neeg mob zoo rau cov mob ntshav qab zib hom 2 nrog lub cev hnyav 80 kg, 4.4 mmol / L * 64 kg / 80 kg = 3.52 mmol / L.

Peb tau pom tias rau peb tus neeg mob, qhov tsawg kawg ntawm kev nce siab hauv cov ntshav qab zib ib hmo yog 4.0 mmol / L. Nws lub cev hnyav yog 80 kg. Rau nws, raws li kev ntsuas "ceev faj" ntawm 1 U ntawm cov tshuaj insulin ntev, nws yuav txo cov ntshav qab zib kom tsawg li 3.52 mmol / L. Hauv qhov no, rau nws, kev pib muab cov tshuaj insulin thaum tsaus ntuj yuav yog 4.0 / 3.52 = 1.13 units. Sau kom ze rau 1/4 PIECES ze thiab tau 1.25 PIECES. Txhawm rau txhawm rau txhawm rau qhov kev txhaj tshuaj qis no, koj yuav tsum kawm paub txhawm rau insulin. Lantus yuav tsum tsis txhob qhaj. Yog li ntawd, nws yuav tsum tau txaij 1 koog lossis tam sim ntawd 1.5 yam. Yog tias koj siv Levemir hloov Lantus, tom qab ntawd ntuag nws kom raug txhaj 1.25 PIECES.

Yog li, lawv tau txhaj cov koob tshuaj thaum pib txuas ntxiv thaum hmo ntuj. Hauv cov hnub tom qab no, peb kho nws - nce lossis txo kom txog thaum muaj suab thaj thaum sawv ntxov nyob rau ntawm lub plab khoob yog qhov ruaj khov ntawm 4.6 ± 0.6 mmol / l. Yuav kom ua tiav qhov no, koj yuav tsum cais cov koob tshuaj Lantus, Levemir lossis Protafan rau yav hmo ntuj thiab prick ib feem tom qab ntawm ib tag hmo. Nyeem cov ntsiab lus saum toj no hauv kem “Yuav ua li cas ua kom qab zib sai thaum sawv ntxov”.

Txhua txhua hom 1 lossis hom 2 cov neeg mob ntshav qab zib uas nyob rau hauv kev noj haus cov zaub mov uas muaj carbohydrate tsawg yuav tsum kawm paub yuav txo cov tshuaj insulin kom txhaj tshuaj tsawg. Thiab yog tias koj tseem tsis tau hloov mus rau kev noj zaub mov kom tsis rog nrog cov zaub mov qab zib, yog li koj ua dabtsi ntawm no?

Kev kho ntawm cov koob tshuaj ntawm lub caij nyoog insulin thaum hmo ntuj

Yog li, peb xam tawm yuav laij kwv yees cov pib kwv yees ncua ntawm insulin thaum hmo ntuj. Yog tias koj tau kawm kev laij zauv hauv tsev kawm, tom qab ntawd koj tuaj yeem kho nws. Tab sis qhov ntawd tsuas yog qhov pib xwb. Vim tias qhov pib noj tshuaj zoo li yuav yog qhov tsawg dua lossis nce siab dua. Txhawm rau kho cov koob tshuaj ntawm cov insulin ntev ntev thaum hmo ntuj, koj sau koj cov piam thaj hauv ntshav thaum mus pw rau ob peb hnub, thiab tom qab ntawv thaum sawv ntxov ntawm lub plab khoob. Yog tias qhov siab tshaj plaws nce hauv qab zib hauv ib hmo tsis siab dua li 0.6 mmol / l - tom qab ntawd cov koob tshuaj yog qhov tseeb. Hauv qhov no, koj yuav tsum coj mus rau hauv tus account tsuas yog cov hnub uas koj tau noj hmo tsis pub dhau 5 teev ua ntej mus pw. Noj thaum ntxov yog ib qho tseem ceeb rau cov neeg mob ntshav qab zib uas tau raug kho mob los ntawm insulin.

Yog tias qhov nce siab tshaj hauv cov piam thaj hauv ib hmo dhau ntawm 0.6 mmol / L - nws txhais tau hais tias qhov koob tshuaj thaum yav tsaus ntuj txuas ntxiv insulin yuav tsum tau sim nce. Yuav ua li cas yuav ua rau nws? Nws yog ib qho tsim nyog yuav tau nce nws los ntawm 0.25 PIECES txhua 3 hnub, thiab tom qab ntawd txhua txhua hnub los saib xyuas seb qhov no yuav cuam tshuam li cas hmo ntuj nce ntxiv nyob rau hauv cov ntshav qab zib. Txuas ntxiv maj mam nce cov koob tshuaj kom txog rau thaum cov piam thaj thaum sawv ntxov tsis tshaj 0.6 mmol / L siab dua koj cov qab zib yav tsaus ntuj. Rov nyeem dua yuav ua li cas tswj thaum sawv ntxov thaum kaj ntug.

Li cas los xaiv qhov zoo tshaj koob ntawm cov tshuaj insulin thaum hmo ntuj:

Koj yuav tsum tau kawm paub noj mov kom ntxov, 4-5 teev ua ntej yuav mus pw.
Yog tias koj tau noj hmo lig, tom qab ntawd ib hnub twg yuav tsis haum rau kev kho qhov tshuaj ntxiv ntawm cov tshuaj insulin thaum hmo ntuj.
Ib zaug ib lim tiam nyob rau hnub sib txawv, xyuas koj cov qab zib ib nrab hnub. Nws yuav tsum muaj tsawg kawg yog 3.5-3.8 mmol / L.
Ua kom ntau ntxiv thaum yav tsaus ntuj cov koob tshuaj txuas ntxiv yog tias 2-3 hnub nyob rau hauv kab hauv qab zib thaum sawv ntxov ntawm lub plab khoob yog ntau dua 0.6 mmol / L siab dua nws tau ua nag hmo ua ntej yuav mus pw.
Dhau ntawm taw qhia - xav txog tsuas yog cov hnub thaum koj tau noj hmo thaum ntxov!
Rau cov neeg mob uas muaj ntshav qab zib hom 1 thiab ntshav qab zib hom 2 uas ua raws li cov zaub mov uas muaj protein ntau. Qhov kev txhaj tshuaj ntawm cov insulin ntev li thaum hmo ntuj tau pom zoo kom nce los ntawm tsis ntau tshaj 0.25 units txhua 3 hnub. Lub hom phiaj yog txhaib koj tus kheej kom ntau li ntau tau los ntawm nocturnal hypoglycemia.
Tseem Ceeb! Yog tias koj tau tshaj tawm cov tshuaj insulin yav tsaus ntuj - 2-3 hnub ntxiv, nco ntsoov xyuas koj cov piam thaj hauv ib tag hmo.
Yuav ua li cas yog tias cov piam thaj thaum hmo ntuj txia ntshis ua qis dua li qub los yog npau suav phem thab koj? Yog li, koj yuav tsum txo qis cov koob tshuaj insulin, uas txhaj ua ntej yuav mus pw.
Yog tias koj xav tau qis dua li kev noj tshuaj yav tsaus ntuj ntawm cov tshuaj insulin, nws raug nquahu kom hloov qee qhov ntawm nws mus rau kev txhaj tshuaj ntxiv thaum 1-3 teev sawv ntxov.

Kev tiv thaiv ntawm nocturnal hypoglycemia

Nyeem cov ntawv sau tseem ceeb, Kev Hypoglycemia hauv Ntshav Qab Zib. Kev tiv thaiv thiab pab cuam ntawm hypoglycemia. "

Nightly hypoglycemia nrog tus npau suav phem yog qhov tsis zoo txaus ntshai thiab txawm tias txaus ntshai yog tias koj nyob ib leeg. Cia peb paub yuav tiv thaiv nws li cas thaum koj nyuam qhuav pib kho koj cov ntshav qab zib nrog kev txhaj tshuaj ntxiv thaum tsaus ntuj. Teeb lub tswb kom nws tsa koj li 6 teev tom qab txhaj tshuaj. Thaum koj sawv, ntsuas koj cov ntshav qab zib nrog ib glucometer. Yog tias nws qis dua 3.5 mmol / l, noj me ntsis carbohydrates kom tsis muaj ntshav qab zib. Tswj koj cov piam thaj hmo ntuj thaum ntxov ntawm kev kho mob ntshav qab zib insulin, zoo li txhua zaus koj sim nce cov koob tshuaj insulin ntau hmo. Txawm hais tias ib kis zoo li no txhais tau tias yuav tsum tau txhaj koob tshuaj.

Yuav luag txhua tus neeg mob ntshav qab zib qis yuav tsum tau txhaj tshuaj ntxiv ib hnub twg tsawg dua 8 ib pawg. Ib qho kev zam rau txoj cai no yog cov neeg mob uas muaj hom 1 lossis 2 mob ntshav qab zib, rog rog, mob ntshav qab zib, thiab rau cov neeg tam sim no muaj kab mob kis. Yog tias koj txhaj cov tshuaj insulin txuas ntxiv thaum hmo ntuj ntawm 7 koob lossis ntau dua, ces nws cov khoom hloov pauv, piv nrog cov koob tshuaj me. Nws siv sijhawm ntev dua. Hypoglycemia tej zaum yuav tshwm sim ua ntej noj hmo tom qab. Txhawm rau zam cov teeb meem no, nyeem "Yuav ua li cas txhaj tshuaj insulin ntau" thiab ua raws li cov lus pom zoo.

Yog tias koj xav tau koob tshuaj Lantus, Levemir lossis Protafan yav tsaus ntuj ntau, uas yog, nws tshaj 8 ntu, tom qab ntawd peb xav kom faib nws tom qab, thaum ib tag hmo. Nyob rau yav tsaus ntuj, cov neeg mob ntshav qab zib npaj txhua yam khoom tsim nyog, tsim lub moos ceeb toom nyob rau hauv nruab nrab ntawm qhov tsaus ntuj, thiab thaum lawv hu nyob rau hauv lub xeev ib nrab tsis nco qab, lawv txhaj lawv tus kheej thiab tam sim ntawd tsaug zog dua. Vim tias qhov no, cov txiaj ntsig kho mob ntshav qab zib tau zoo dua. Nws tsim nyog kom tsis yooj yim los tiv thaiv kev mob ntshav qab zib thiab kom cov ntshav qab zib ib txwm nyob tag kis. Ntxiv mus, qhov tsis yooj yim yuav muaj tsawg heev thaum koj kawm kho cov txheej txheem ntawm cov tshuaj insulin tsis muaj tshuaj.

Koj puas xav tau txhaj cov tshuaj insulin txuas ntxiv thaum sawv ntxov?

Yog li, peb tau xam seb yuav ua li cas txhav txhawm rau Latnus, Levemir lossis Protafan rau hmo ntuj. Ua ntej peb txiav txim siab seb puas yuav ua txhua yam no. Yog tias nws hloov tawm tias koj xav tau, ces peb suav thiab muaj feem rau cov tshuaj pib. Thiab tom qab ntawd peb kho nws kom txog thaum qab zib thaum sawv ntxov ntawm lub plab khoob ib txwm yog 4.6 ± 0.6 mmol / l. Thaum ib tag hmo, nws yuav tsum tsis poob qis dua 3.5-3.8 mmol / L. Qhov tseem ceeb uas koj tau kawm ntawm peb lub vev xaib yog kom txhaj tshuaj insulin ntxiv nyob hauv ib tag hmo kom tswj thaum sawv ntxov. Ib feem ntawm qhov koob tshuaj yav tsaus ntuj yog pauv mus rau nws.

Tam sim no cia peb txiav txim siab thaum sawv ntxov ntawm cov insulin txuas ntxiv. Tab sis ntawm no tuaj qhov nyuaj. Txhawm rau daws teeb meem nrog kev txhaj tshuaj ntawm cov tshuaj insulin txuas ntxiv thaum sawv ntxov, koj yuav tsum tau tshaib plab thaum nruab hnub los ntawm hmo ua hmo. Peb txhaj Lantus Levemir lossis Protafan los ua kom cov piam thaj sai sai. Thaum hmo ntuj koj tsaug zog thiab tshaib plab ib txwm muaj. Thiab yav tav su los saib xyuas cov piam thaj hauv ib plab khoob, koj yuav tsum ceev faj kom tsis txhob noj mov. Hmoov tsis zoo, qhov no tsuas yog qhov tseeb los xam cov koob tshuaj thaum sawv ntxov ntawm cov tshuaj insulin txuas ntxiv. Cov txheej txheem hauv qab no yog piav qhia txhua yam.

Piv txwv koj muaj dhia hauv qab zib thaum nruab hnub lossis nws pheej nce siab ntxiv.Cov lus nug ntawm qhov tseem ceeb: koj cov piam thaj puas nce los ntawm kev noj mov lossis ntawm lub plab khoob? Rov qab hais tias cov tshuaj insulin txuas ntxiv yog xav kom tswj cov suab thaj kom sai, thiab ceev ceev - kom tsis txhob muaj cov piam thaj hauv ntshav ntxiv tom qab noj mov. Peb kuj tseem siv cov tshuaj tua kab hluav taws (ultrashort insulin) kom nrawm qab zib kom ib txwm yog nws tseem dhia.

Ua kom cov ntshav qab zib tom qab noj insulin luv luv los yog txhaj insulin txuas ntxiv thaum sawv ntxov kom cov piam thaj ib txwm ntawm ib plab plab txhua hnub yog qhov txawv. Yog li, nws yog qhov tseem ceeb heev kom paub txog seb koj cov piam thaj coj li cas thaum nruab hnub, thiab tsuas yog tom qab ntawd tau sau tshuaj kho insulin rau lub hnub. Cov kws tshaj lij cov kws kho mob thiab cov ntshav qab zib tau sim siv cov tshuaj insulin luv nyob rau nruab hnub uas xav tau ntev ntev, thiab rov ua dua. Cov txiaj ntsig yog deplorable.

Nws yog qhov tsim nyog los ntawm kev sim ua kom paub seb koj cov piam thaj hauv ntshav yuav ua licas thaum nruab hnub. Nws puas sawv los ntawm kev noj mov lossis ntawm lub plab khoob ib yam nkaus? Hmoov tsis zoo, koj yuav tsum tshaib plab kom tau txais cov ntaub ntawv no. Tab sis ib qho kev sim yog qhov tsim nyog tiag. Yog tias koj tsis xav tau cov tshuaj insulin ntev ntev thaum hmo ntuj los them rau yav sawv ntxov thaum sawv ntxov, ces nws tsis zoo li tias koj cov piam thaj hauv ntshav yuav nce thaum nruab hnub ntawm lub plab khoob. Tab sis tseem koj yuav tsum txheeb xyuas thiab paub tseeb. Ntxiv mus, koj yuav tsum ua qhov kev sim yog tias koj tau txhaj tshuaj ntxiv thaum tsaus ntuj.

Yuav ua li cas xaiv cov koob tshuaj ntawm Lantus, Levemir lossis Protafan thaum sawv ntxov:

Hnub ntawm kev sim, tsis txhob noj tshais lossis su, tab sis npaj noj hmo 13 teev tom qab koj sawv. Nov yog lub caij uas koj tseem cia sijhawm tsaus ntuj xwb.
Yog tias koj noj Siofor lossis Glucofage Ntev, tom qab ntawd noj koj li ib txwm noj thaum sawv ntxov.
Haus dej kom txaus nyob thoob plaws hnub; koj tuaj yeem siv tshuaj yej ntsuab yam tsis muaj qab zib. Tsis txhob mob siab rau qhuav. Kas fes, cocoa, dub thiab ntsuab dej xas - nws zoo dua tsis haus.
Yog tias koj noj tshuaj kho ntshav qab zib uas tuaj yeem ua rau ntshav qab zib tau qis, ces hnub no tsis txhob noj lawv thiab feem ntau tso lawv tseg. Nyeem seb hom tshuaj ntshav qab zib twg tsis zoo thiab yam twg zoo.
Ntsuas koj cov ntshav qab zib nrog ib glucometer sai li sai tau koj sawv, ces tom qab 1 teev, tom qab 5 teev, tom qab 9 teev, tom qab 12 teev thiab 13 teev ua ntej noj hmo. Nyob rau hauv tag nrho, koj yuav siv 5 ntsuas thaum nruab hnub.
Yog tias thaum 13 teev ntawm hnub yoo mov thaum nruab hnub cov piam thaj tau nce ntau dua 0.6 mmol / l thiab tsis poob, tom qab ntawd koj xav tau txhaj tshuaj insulin ntxiv thaum sawv ntxov nyob rau ntawm lub plab khoob. Peb suav cov koob tshuaj ntawm Lantus, Levemir lossis Protafan rau cov kev txhaj tshuaj no zoo ib yam li cov tshuaj txuas ntxiv thaum hmo ntuj.

Hmoov tsis zoo, txhawm rau kho lub sijhawm thaum sawv ntxov ntawm cov insulin ntev ntev, ib qho yuav tsum yoo kom nrawm nrawm rau ib hnub tsis tiav thiab saib seb ntshav qab zib cov ntshav coj li cas rau hnub no. Ciaj sia nyob kev tshaib plab hnub ob zaug hauv ib lub lis piam tsis kaj siab heev. Yog li, tos kom txog rau lub asthiv tom ntej ua qhov kev sim tib yam kom kho koj qhov koob tshuaj thaum sawv ntxov ntev. Peb taw qhia tias txhua qhov txheej txheem muaj teeb meem no tsuas yog tsim nyog rau cov neeg mob uas ua raws li cov zaub mov tsis muaj roj ntau ntau thiab sim ua kom muaj suab thaj zoo li qub 4.6 ± 0.6 mmol / L. Yog tias qhov sib txawv ntawm ± 2-4 mmol / l tsis thab koj, ces koj tsis tuaj yeem thab.

Muaj ntshav qab zib hom 2, pom tau tias koj xav tau tshuaj insulin sai ua ntej noj mov, tab sis koj tsis tas yuav siv tshuaj insulin ntxiv thaum sawv ntxov. Txawm li cas los xij, qhov no tsis tuaj yeem kwv yees tsis tau kev sim, yog li tsis txhob tub nkeeg kom coj nws tawm.

Piv txwv tias koj pib kho cov ntshav qab zib hom 2 nrog kev ncua tshuaj insulin thaum hmo ntuj, thiab tej zaum tseem tuaj thaum sawv ntxov. Tom qab ib ntus, koj yuav pom qhov tseeb ntawm cov tshuaj insulin txhawm rau kom cov ntshav qab zib sai li 24 teev nyob rau ib hnub. Raws li qhov tshwm sim ntawm qhov no, tus txiav ua ke tuaj yeem cuam tshuam li ntawd txawm tias tsis muaj qhov xav tau ntawm cov tshuaj insulin nws yuav nquag ua kom muaj suab thaj ntau ntxiv tom qab noj mov. Qhov no feem ntau tshwm sim nrog cov mob sib khuav ntawm hom 2 mob ntshav qab zib. Tab sis yog tias tom qab noj koj cov ntshav qab zib kom ntau dua 0.6 mmol / L siab dua li ib txwm muaj rau cov neeg noj qab haus huv, tom qab ntawd koj tseem xav tau txhaj tshuaj luv luv insulin ua ntej noj mov. Rau cov ntsiab lus ntxaws ntxiv, saib "Kev xam ntawm cov koob tshuaj sai ntawm cov insulin ua ntej noj mov."

Kev nthuav tshuaj insulin Lantus thiab Levemir: cov lus teb rau cov lus nug

Glycated hemoglobin txo qis mus rau 6.5% - zoo, tab sis tseem muaj haujlwm yuav ua :). Lantus tuaj yeem hlais tau ob hnub ib hnub. Ntxiv mus, peb xav kom txhua tus ua qhov no los txhim kho kev tswj ntshav qab zib. Muaj qee qhov laj thawj los xaiv Levemir hloov ntawm Lantus, tab sis lawv tsis muaj txiaj ntsig. Yog tias Lantus raug muab pub dawb, tab sis Levemir - tsis yog, tom qab ntawd hno cov tshuaj insulin ob zaug ib hnub uas lub xeev muab rau koj.

Raws li rau qhov tsis sib xws ntawm Lantus thiab NovoRapid thiab lwm yam kev hloov pauv ntawm cov kua dej los ntawm cov tuam ntxhab sib txawv. Cov no yog cov lus xaiv ruam, tsis lees paub los ntawm ib yam dab tsi. Txaus siab rau lub neej thaum koj tau txais cov tshuaj insulin zoo rau dawb. Yog tias koj yuav tsum hloov mus rau hauv tsev, tom qab ntawd koj tseem yuav nco txog lub sijhawm no nrog nostalgia. Hais txog "nws tau ua kev nyuaj rau kuv los pab them cov ntshav qab zib." Hloov mus rau kev noj haus cov zaub mov kom tsis txhob rog thiab ua raws li tag nrho lwm cov dej num teev hauv peb hom phiaj xwm ntshav qab zib hom 1. Kuv pom zoo kom txhaj Lantus tsawg kawg ob zaug hauv ib hnub, yav sawv ntxov thiab yav tsaus ntuj, thiab tsis yog ib zaug, raws li txhua tus nyiam ua.

Kuv yuav nyob hauv koj qhov chaw, Rov qab, mob siab rau Lantus, thiab ob zaug ib hnub, thiab tsis yog thaum tsaus ntuj. Hauv qhov no, koj tuaj yeem sim ua kom tsis muaj kev siv tshuaj los ntawm Apidra. Hloov mus rau qhov kev noj haus cov zaub mov kom tsis txhob rog thiab ua raws txhua yam haujlwm tau hais tseg hauv hom 2 kho mob ntshav qab zib. Ua kev saib xyuas ntshav qab zib tag nrho 1-2 zaug hauv ib lub lis piam. Yog tias koj ua tib zoo ua raws li kev noj zaub mov noj, noj tshuaj rau ntshav qab zib hom 2, thiab tseem ntau tshaj yog ua kev tawm dag zog lub cev nrog kev lom zem, tom qab ntawd muaj 95% qhov koj yuav ua tau yam tsis muaj kev txhaj tshuaj insulin txhua. Yog tias tsis muaj suab thaj koj cov piam thaj tseem yuav nyob siab dua li ib txwm, tom qab ntawd txhaj Lantus ua ntej. Kev hno ntshav ntawm cov insulin sai ua ntej noj mov nrog hom ntshav qab zib hom 2 tsuas yog xav tau nyob rau hauv cov mob nyhav tshaj plaws, yog tias tus neeg mob dhau mus dhau los ua raws li cov zaub mov muaj protein tsawg thiab feem ntau ua raws li kev tswj hwm.

Nyeem kab lus “Cov Kev Txhaj Tshuaj insulin”. Xyaum ua me ntsis - thiab kawm paub yuav ua li cas cov kev txhaj tshuaj no tsis mob kiag li. Qhov no yuav coj tau txiaj ntsig zoo rau koj tsev neeg tag nrho.

Yog, nws yog. Ntxiv mus, koj yuav tsum txawm yuav Lantus lossis Levemir rau koj cov nyiaj, tsis txhob siv cov "nruab nrab" protafan dawb. Vim li cas - tham nyob rau hauv kom meej saum toj no.

Neuropathy, mob ntshav qab zib ko taw thiab lwm cov teeb meem yog nyob ntawm seb koj tswj hwm li cas kom koj cov ntshav qab zib nyob ze li qub. Cov tshuaj insulin koj siv dab tsi tsis tseem ceeb yog tias nws pab txhawm rau them ntshav qab zib kom zoo. Yog tias koj hloov los ntawm protafan mus rau Levemir lossis Lantus ua lub zog insulin ntxiv, tom qab ntawd tswj kev mob ntshav qab zib tau yooj yim dua. Tus mob ntshav qab zib tau tshem ntawm kev mob thiab lwm cov tsos mob ntawm mob neuropathy - qhov no yog vim lawv tau txhim kho cov ntshav qab zib kom tsawg. Thiab cov hom insulin tshwj xeeb tsis muaj dab tsi ua rau nws. Yog tias koj muaj kev txhawj xeeb txog neuropathy, tom qab ntawd nyeem kab lus ntawm alpha lipoic acid.

Los ntawm kev sim nrog kev txhaj tshuaj ntawm cov tshuaj insulin txuas ntxiv, koj tuaj yeem txhim kho koj cov piam thaj thaum sawv ntxov ntawm ib qho khoob khoob. Yog tias koj noj zaub mov "sib npaug", tshaj nrog cov carbohydrates, ces koj yuav tsum siv cov tshuaj Levemir ntau ntau. Hauv qhov no, sim ua ntej txhaj tshuaj thaum yav tsaus ntuj ntawm 22.00-00.00. Tom qab ntawd lub ncov ntawm nws qhov kev nqis tes yuav yog 5.00-8.00 thaum sawv ntxov, thaum qhov tshwm sim ntawm thaum sawv ntxov sawv ntxov yog pom ntau li ntau tau. Yog tias koj hloov mus rau kev noj haus cov zaub mov uas tsis muaj carbohydrate thiab koj cov koob tshuaj ntawm Levemir tsawg, nws pom zoo kom hloov mus rau 3 lossis txawm tias 4 hno ib hnub los ntawm 2-lub sijhawm tswj hwm. Thaum xub thawj, qhov no yog qhov teeb meem, tab sis koj sai sai siv rau nws, thiab sawv ntxov qab zib pib ua rau koj zoo siab heev.

Koj cov kws kho mob paub meej tias tsis muaj dab tsi ua. Yog tias nyob rau 4 lub xyoo koj tsis tau tsim kev fab tshuaj rau insulin, ces nws tsis zoo li nws yuav tshwm sim sai. Kuv kos duab rau cov hauv qab no. Kev noj zaub mov zoo rau cov ntshav qab zib kom tsis tsuas txhim kho cov ntshav qab zib, tab sis kuj tseem txo qhov muaj feem ua xua.Vim tias yuav luag txhua cov khoom lag luam uas tuaj yeem ua rau ua xua, peb cais tawm ntawm cov khoom noj, tsuas yog rau cov qe qaib.

Tsis yog, tsis muaj tseeb. Muaj lus xaiv tias Lantus ua rau mob qog noj ntshav, tab sis lawv tseem tsis tau lees paub. Xav tias xav hloov ntawm protafan mus rau Levemir lossis Lantus - txuas ntxiv cov tshuaj insulin. Muaj qee qhov laj thawj vim li cas nws yog qhov zoo dua los xaiv Levemir dua li Lantus. Tab sis yog tias Lantus tau muab tshuaj pub dawb, tab sis Levemir - tsis yog, tom qab ntawd maj mam txhaj cov tshuaj insulin dawb. Lus khaws xav Peb pom zoo kom txhaj Lantus ob rau peb zaug ib hnub, thiab tsis yog ib zaug.

Koj tsis qhia koj lub hnub nyoog, qhov siab, qhov hnyav, hom mob ntshav qab zib thiab sijhawm nyob hauv qhov tsis muaj qab hau. Nws tsis muaj qhov pom tseeb rau koj lo lus nug. Koj tuaj yeem faib 15 units ib nrab. Los yog txo tag nrho cov koob tshuaj los ntawm 1-2 units thiab twb tau faib nws ib nrab. Lossis koj tuaj yeem pleev ntau thaum yav tsaus ntuj dua li thaum sawv ntxov los txhawm rau thaum sawv ntxov. Tag nrho cov no yog tus neeg. Ua kom tswj tus kheej los ntawm cov ntshav qab zib thiab tau ua pov thawj los ntawm nws cov txiaj ntsig. Nyob rau hauv txhua rooj plaub, hloov ntawm ib qho Lantus txhaj ib hnub rau ob yog qhov raug.

Nws tsis muaj lus teb meej rau koj cov lus nug. Ua kom tswj tus kheej los ntawm cov ntshav qab zib thiab tau ua pov thawj los ntawm nws cov txiaj ntsig. Nov yog tib txoj kev los xaiv qhov kev ncua ntev thiab ceev tshaj tawm cov tshuaj insulin. Kuv xav kom koj xam phaj nrog cov niam txiv ntawm cov menyuam muaj hnub nyoog 6 xyoo uas muaj mob ntshav qab zib hom 1. Lawv tswj kom dhia tawm cov tshuaj insulin kom zoo tom qab lawv hloov mus rau qhov kev noj haus kom yog.

Siv tshuaj insulin ntau, uas Levemir nyob tsis yog, tsis yog xav kom txo qis ntshav qab zib kom sai. Lub hom phiaj ntawm nws txoj kev siv yog sib txawv. Qab zib hauv koj qhov xwm txheej nce hauv qab ntawm cov khoom noj uas koj nyuam qhuav noj. Qhov no txhais tau hais tias qhov koob tshuaj sai ntawm cov kua dej ua ntej noj mov tsis raug xaiv tsis raug. Thiab, feem ntau yuav yog, lub ntsiab yog noj zaub mov tsis zoo. Nyeem peb Qhov Hom Ntshav Qab Zib Hom 1 lossis Hom Ntshav Qab Zib Hom 2. Tom qab ntawv, ua tib zoo kawm tag nrho cov lus hauv Insulin.

Txuas insulin ntxiv hauv hom 1 thiab hom 2 ntshav qab zib: kev tshawb pom

Hauv tsab xov xwm, koj tau kawm paub meej txog Lantus thiab Levemir, kev ua yeeb yam ntev ntev, thiab nruab nrab NPH-insulin protafan yog dab tsi. Peb tau xam tawm yog vim li cas nws yog qhov tseeb rau siv cov kev txhaj tshuaj ntawm cov insulin txuas ntxiv thaum hmo ntuj thiab thaum sawv ntxov, thiab rau lub hom phiaj dab tsi nws tsis yog lawm. Qhov tseem ceeb tshaj plaws uas yuav tsum tau kawm: kev ua lub cev txuas ntxiv insulin txhawb cov ntshav qab zib sai sai. Nws tsis yog rau tua cov dhia hauv qab zib tom qab noj mov.

Tsis txhob sim siv cov tshuaj insulin txuas ntxiv qhov twg luv los sis luv luv qhov xav tau. Nyeem kab lus “Ultrashort Insulin Humalog, NovoRapid thiab Apidra. Tib Neeg Muaj Insulin luv luv thiab ”Kev txhaj tshuaj ntawm cov insulin ceev ua ntej noj mov. Yuav ua li cas kom qis qab zib kom zoo yog tias nws dhia. " Kev kho koj cov ntshav qab zib kom txaus nrog insulin yog tias koj xav kom zam nws cov teeb meem.

Peb tau saib yuav ua li cas los laij cov tshuaj uas tsim nyog ntawm cov tshuaj insulin ntxiv thaum tsaus ntuj thiab thaum sawv ntxov. Peb qhov kev pom zoo yog qhov txawv ntawm qhov tau sau hauv phau ntawv nrov thiab dab tsi yog qhia hauv "tsev kawm mob ntshav qab zib". Nrog kev pab los ntawm kev ua tib zoo saib xyuas tus menyuam cov ntshav qab zib, nco ntsoov tias peb cov hauv kev muaj txiaj ntsig zoo, txawm hais tias lub sijhawm ua haujlwm zoo. Txhawm rau xam thiab kho qhov ntau npaum li cas ntawm cov tshuaj insulin thaum sawv ntxov, koj yuav tsum hla kev noj tshais thiab noj su. Qhov no tsis txaus siab heev, tab sis alas, ib txoj kev zoo dua tsis muaj nyob. Xam thiab kho qhov ntau npaum li cas ntawm kev txuas ntxiv cov insulin thaum hmo ntuj yog yooj yim dua, vim tias thaum hmo ntuj, thaum koj pw, koj tsis noj nyob rau hauv txhua kis.

Xav ntev ntxiv insulin Lantus, Levemir thiab protafan xav tau kom cov piam thaj ib txwm nyob ib plab khoob rau ib hnub.
Ultrashort thiab insulin luv luv - tso cov suab thaj uas tau tshwm sim tom qab noj mov.
Tsis txhob sim siv cov tshuaj insulin ntau dua li qhov hloov cov tshuaj insulin sai ua ntej noj mov!
Cov tshuaj insulin twg zoo dua - Lantus lossis Levemir? Teb: Levemir muaj qhov zoo me me.Tab sis yog tias koj tau txais Lantus dawb, tom qab ntawd calmly prick nws.
Ntawm hom 2 mob ntshav qab zib, thawj zaug txhaj txuas ntxiv insulin thaum hmo ntuj thiab / lossis thaum sawv ntxov, thiab tom qab ntawd mam li yaug insulin ua ntej noj mov, yog tias tsim nyog.
Nws yog qhov pom zoo kom hloov los ntawm protafan mus rau Lantus lossis Levemir, txawm tias koj yuav tsum yuav cov tshuaj insulin ntxiv rau koj cov nyiaj.
Tom qab hloov mus rau kev noj haus cov zaub mov kom tsawg rau cov ntshav qab zib hom 1 lossis 2, cov koob tshuaj ntawm txhua hom tshuaj insulin raug txo los ntawm 2-7 zaug.
Kab lus qhia cov lus qhia ib qib zuj zus hais txog yuav ua li cas los xam qhov ntau npaum li cas ntawm cov tshuaj insulin thaum hmo ntuj thiab thaum sawv ntxov. Tshawb nrhiav lawv!
Nws raug nquahu kom txhaj ntxiv Lantus, Levemir lossis Protafan ntawm 1-3 a.m. txhawm rau tswj tau qhov xwm txheej zoo thaum sawv ntxov.
Cov neeg mob ntshav qab zib, uas tau noj hmo 4-5 teev ua ntej yuav mus pw thiab ntxiv cov koob tshuaj insulin ntxiv thaum 1-3 teev sawv ntxov, muaj cov piam thaj ib txwm nyob rau yav sawv ntxov ntawm lub plab khoob.

Kuv vam tias tsab xov xwm no tau pab tau koj. Yog tias ua tau, nws raug nquahu kom hloov nruab nrab NPH-insulin (protafan) nrog Lantus lossis Levemir txhawm rau txhim kho cov txiaj ntsig ntawm kev kho mob ntshav qab zib. Hauv cov lus pom, koj tuaj yeem nug cov lus nug txog kev kho ntshav qab zib nrog cov tshuaj insulin txuas ntxiv. Tus xaib xaib sai teb.

Tshuaj insulin Humulin: tshuaj xyuas, cov lus qhia, tus nqi tshuaj npaum li cas

Hauv 1 ml. Cov tshuaj Humulin Humulin muaj 100 IU ntawm tib neeg cov tshuaj insulin. Cov khoom xyaw nquag yog 30% solulin insulin thiab 70% insulin isofan.

Raws li cov koom haum pab siv:

distilled metacresol,
phenol
sodium hydrogen phosphate heptahydrate,
hydrochloric acid,
glycerol
zinc oxide
tshuaj sulfate,
sodium hydroxide
dej.

Kev taw qhia rau siv thiab phiv

Mob ntshav qab zib mellitus, nyob rau hauv uas kev kho tshuaj insulin yog kev pom zoo.
Mob ntshav qab zib Gestational (ntshav qab zib ntawm cov poj niam cev xeeb tub).

Tsim cov tshuaj hypoglycemia.
Kev ua haujlwm tsis zoo.

Feem ntau thaum lub sij hawm kho nrog insulin npaj, suav nrog Humulin M3, tau pom kev txhim kho hypoglycemia. Yog tias nws muaj daim ntawv foos hnyav heev, nws tuaj yeem ua rau mob ntshav tsis qab los (tsis nco qab thiab tsis nco qab) thiab txawm ua rau tus neeg mob tas sim neej.

Hauv qee tus neeg mob, kev tawm tsam tuaj yeem tshwm sim, ua kom tawv nqaij ua pob khaus, o thiab liab rau ntawm thaj chaw txhaj tshuaj. Feem ntau, cov tsos mob no ploj ntawm lawv tus kheej hauv ob peb hnub lossis ntau lub lis piam tom qab pib kho.

Qee zaum qhov no tsis muaj kev sib txuas nrog kev siv cov tshuaj nws tus kheej, tab sis yog los ntawm tus ntawm lwm yam los yog kev txhaj tshuaj tsis yog.

Muaj ua xua tshwm sim ntawm ib tug systemic. Nws tshwm sim ntau tsawg dua, tab sis muaj qhov hnyav dua. Nrog rau kev fab tshuaj, cov hauv qab no tshwm sim:

ua pa nyuaj
dav khaus
lub plawv dhia
ua ntshav siab
txog siav
tawm hws ntau dhau.

Feem ntau, cov ua xua tuaj yeem cuam tshuam tus neeg mob lub neej thiab xav tau kev kho mob xwm txheej ceev. Qee zaum cov insulin los hloov lossis desensitization yuav tsum.

Thaum siv tsiaj cov tshuaj insulin, kev tawm tsam, txo lub cev tsis zoo rau cov tshuaj, los yog lipodystrophy yuav loj hlob tuaj. Thaum sau ntawv ntawm insulin Humulin M3, qhov tshwm sim ntawm qhov tshwm sim no yuav luag tsis tau.

Cov lus qhia rau kev siv

Cov tshuaj insulin Hum3 M3 tsis raug tso cai muab tshuaj rau qhov leeg ntshav.

Thaum sau daim ntawv tshuaj insulin, koob tshuaj thiab hom kev tswj hwm tsuas yog xaiv los ntawm kws kho mob. Qhov no tau ua ib tus zuj zus rau txhua tus neeg mob, nyob ntawm qib glycemia hauv nws lub cev. Humulin M3 yog npaj rau kev coj ua subcutaneous, tab sis nws kuj tseem tuaj yeem ua intramuscularly, insulin tso cai qhov no. Nyob rau hauv txhua rooj plaub, tus mob ntshav qab zib yuav tsum paub yuav ua li cas txhaj tshuaj insulin.

Subcutaneously, cov tshuaj raug txhaj rau hauv plab, ncej puab, xub pwg lossis pob tw. Nyob rau tib qho chaw txhaj tshuaj tuaj yeem tsis pub tshaj ib hlis ib zaug.Thaum ua cov txheej txheem, nws yog ib qho tsim nyog siv cov khoom siv txhaj tshuaj kom raug, txhawm rau tiv thaiv rab koob kom tsis txhob nkag rau hauv cov hlab ntshav, tsis txhob zaws rau qhov chaw txhaj tshuaj tom qab txhaj.

Humulin M3 yog ib qho npaj tau tov nrog Humulin NPH thiab Humulin tsis tu ncua. Qhov no ua rau nws tuaj yeem tsis npaj qhov kev daws teeb meem ua ntej coj mus rau tus neeg mob nws tus kheej.

Txhawm rau npaj cov tshuaj insulin rau kev txhaj tshuaj, lub vial lossis daim cartridge ntawm Humulin M3 NPH yuav tsum tau dov 10 zaug hauv koj txhais tes thiab, tig mus 180 degrees, maj mam co ntawm ib sab. Qhov no yuav tsum tau ua kom txog rau thaum qhov kev ncua ntawv zoo li mis los yog kua huab, yam kua.

Nquag co insulin NPH tsis pom zoo, vim tias qhov no tuaj yeem ua rau pom kev ua npuas ncauj thiab cuam tshuam nrog kev siv pes tsawg. Tsis txhob siv cov tshuaj nrog sediment lossis plaub ya ri tuaj tom qab tov.

Kev tswj hwm insulin

Txhawm rau txhawm rau txhaj tshuaj, koj yuav tsum xub ua qee yam txheej txheem ua ntej. Ua ntej koj yuav tsum txiav txim siab qhov chaw txhaj tshuaj, ntxuav koj txhais tes kom zoo thiab so cov chaw no nrog daim ntaub ntub dej hauv cawv.

Tom qab ntawd koj yuav tsum tshem lub hau tiv thaiv los ntawm koob txhaj tshuaj, kho qhov tawv nqaij (ncab lossis ntxig nws), ntxig rau rab koob thiab ua ib qho kev txhaj tshuaj. Tom qab ntawd lub koob yuav tsum tau muab tshem tawm thiab tom qab ob peb feeb, tsis tas yuav muab txhuam, nias qhov chaw txhaj tshuaj nrog lub tshuab ntswg. Tom qab ntawv, nrog kev pabcuam ntawm lub hau tiv thaiv sab nraud, koj yuav tsum tau hle lub koob, tshem nws tawm thiab muab lub hau rov qab rau ntawm xaum xaum xaum.

Koj tsis tuaj yeem siv tib rab koob xaum qhuav ob zaug. Lub vial lossis daim cartridge tau siv mus txog thaum nws siv tag, ces muab pov tseg. Cov xaum kua roj tsuas yog siv rau tus neeg nkaus xwb.

Noj ntau dhau

Humulin M3 NPH, zoo ib yam li lwm yam tshuaj hauv pawg tshuaj no, tsis muaj lub ntsiab lus tseeb ntawm kev noj tshuaj ntau dhau, txij li theem ntawm cov piam thaj hauv cov ntshav cov ntshav yog nyob ntawm kev sib cuam tshuam ntawm cov ntshav nruab nrab, ntshav hauv insulin thiab lwm yam txheej txheem hauv lub cev. Txawm li cas los xij, kev tshaj tawm cov insulin tuaj yeem muaj kev cuam tshuam loj heev.

Kev mob ntshav qab zib yog nce los ntawm qhov tsis sib haum xeeb ntawm cov tshuaj insulin hauv cov ntshav thiab cov nqi zog thiab zaub mov noj.

Cov tsos mob hauv qab no yog cov yam ntxwv ntawm tshwm sim hypoglycemia:

nkees
tachycardia
ntuav
tawm hws ntau dhau,
pallor ntawm daim tawv nqaij
tshee
mob taub hau
tsis meej pem.

Muaj qee kis, piv txwv, nrog cov keeb kwm mob ntshav qab zib mellitus ntev los yog nws txoj kev saib xyuas ze, cov cim ntawm qhov pib ntawm lub qog ntshav yuav hloov. Kev tiv thaiv ntshav qab zib me me tuaj yeem tiv thaiv los ntawm kev noj ntshav qab zib lossis qab zib. Qee zaum koj yuav tau yoog qhov tshuaj insulin, rov qab xyuas cov zaub mov noj lossis hloov ua kom lub cev ua si.

Ntsig ntshav qab zib tsawg yog feem ntau kho los ntawm subcutaneous lossis intramuscular cov thawj coj ntawm glucagon, tom qab los ntawm kev noj zaub mov carbohydrates. Thaum muaj mob hnyav, muaj cov mob puas hlwb, ua kom yauv lossis tsis nco qab, ntxiv rau kev txhaj tshuaj rau glucagon, cov ntshav qabzib yuav tsum tau txhaj tshuaj kom tiav.

Yav tom ntej, txhawm rau tiv thaiv kom txhob rov mob qog ntshav, tus neeg mob yuav tsum noj cov zaub mov uas muaj carbohydrate. Muaj mob ntshav qog ntshav siab yuav tsum tau mus pw hauv tsev kho mob ceev.

Kev Sib Tham Yeeb Tshuaj NPH

Kev ua haujlwm ntawm Humulin M3 yog txhim kho los ntawm kev noj tshuaj hypoglycemic qhov ncauj, ethanol, salicylic acid derivatives, monoamine oxidase inhibitors, sulfonamides, ACE inhibitors, angiotensin II receptor blockers, tsis xaiv-beta-blockers.

Cov tshuaj Glucocorticoid, cov tshuaj hormones kev loj hlob, qhov ncauj tawm tsam, danazole, cov thyroid hormones, thiazide diuretics, beta2-sympathomimetics ua rau txo qis hauv cov nyhuv hypulinlycemic ntawm insulin.

Ua kom muaj zog lossis, hloov pauv, tsis muaj zog ntawm kev vam khom ntawm insulin muaj peev xwm ntawm lancreotide thiab lwm yam analogues ntawm somatostatin.

Cov tsos mob ntawm cov qog ntshav qab zib yog lubricated thaum noj clonidine, reserpine thiab beta-blockers.

Cov nqe lus ntawm kev muag, khaws cia

Humulin M3 NPH muaj muag hauv khw muag tshuaj tsuas yog sau ntawv hauv lub hwj tshuaj.

Cov tshuaj yuav tsum khaws cia ntawm qhov kub txog 2 txog 8 degrees, tsis tuaj yeem ua kom zoo thiab tsis zoo rau tshav ntuj thiab tshav kub.

Ib qho qhib insulin NPH vial tuaj yeem khaws cia ntawm qhov kub ntawm 15 txog 25 degrees rau 28 hnub.

Raws li qhov ntsuas kub uas xav tau, qhov npaj NPH raug khaws cia rau 3 xyoos.

Cov lus qhia tshwj xeeb

Tsis tso cai rau kev kho mob lossis kev teem sijhawm noj tshuaj tsis yog (tshwj xeeb tshaj yog rau cov neeg mob insulin) tuaj yeem ua rau mob ntshav qab zib ketoacidosis lossis hyperglycemia, uas ua rau muaj kev hem thawj rau tus neeg mob lub neej.

Hauv qee tus neeg, thaum siv cov tshuaj insulin, cov tsos mob ntawm tus mob hypoglycemia yuav txawv ntawm cov tsos mob ntawm tus tsiaj insulin, lossis yuav muaj qhov tshwm sim me me.

Tus neeg mob yuav tsum paub tias yog tias cov ntshav qabzib nyob hauv lub cev yog qhov ib txwm muaj (piv txwv li, nrog kev siv tshuaj insulin ntau ntxiv), tom qab ntawd cov tsos mob qhia tias yuav tsum ua rau lub qog ntshav qab zib yuav ploj.

Cov kev tshwm sim no tuaj yeem ua rau qaug zog lossis txawv dua yog tias ib tus neeg noj beta-blockers lossis muaj mob ntshav qab zib ntev ntev, nrog rau muaj cov ntshav qab zib mob neuropathy.

Yog tias hyperglycemia, zoo li hypoglycemia tsis raug kho kom raws sijhawm, qhov no tuaj yeem ua rau tsis nco qab, tsis nco qab, thiab txawm tias tus neeg mob tuag.

Txoj kev hloov ntawm tus neeg mob mus rau lwm txoj kev npaj tshuaj insulin NPH los yog lawv cov hom yuav tsum tau ua tsuas yog nyob ntawm kev saib xyuas ntawm kws kho mob. Hloov cov tshuaj insulin rau cov tshuaj uas muaj cov kev ua txawv, cov txheej txheem tsim tawm (DNA recombinant, tsiaj), hom (npua, analog) yuav xav tau kev kub ntxhov lossis, ntawm qhov tsis sib xws, kev kho kom haum ntawm cov koob tshuaj uas tau hais tseg.

Nrog rau cov kab mob ntawm lub raum lossis mob siab, ua haujlwm tsis txaus ntawm lub plab, ua haujlwm tsis txaus ntawm cov qog adrenal thiab cov thyroid caj pas, tus neeg mob xav tau cov tshuaj insulin yuav poob qis, thiab muaj kev ntxhov siab muaj zog thiab qee yam mob, ntawm qhov tsis sib xws, nce ntxiv.

Tus neeg mob yuav tsum nco ntsoov txog qhov zoo li ntawm kev txhim kho hypoglycemia thiab ntsuam xyuas tau zoo ntawm lub cev ntawm nws lub cev thaum tsav tsheb lossis xav tau haujlwm txaus ntshai.

Monodar (K15, K30, K50),
Novomix 30 Flexspen,
Ryzodeg Flextach,
Humalog sib tov (25, 50).
Gensulin M (10, 20, 30, 40, 50),
Gensulin N,
Tshuaj yaug NPH,
Yawg Farmasulin H 30/70,
Humodar B,
Vosulin 30/70,
Vosulin N,
Mikstard 30 NM
Protafan NM,
Neeg lim hiam.

Cev xeeb tub thiab lactation

Yog tias tus poj niam cev xeeb tub muaj mob ntshav qab zib, yog li nws yog qhov tseem ceeb rau nws los tswj cov mob glycemia. Lub sijhawm no, cov tshuaj insulin feem ntau hloov pauv ntawm ntau lub sijhawm. Hauv thawj peb lub hlis, nws poob, thiab hauv zaum ob thiab thib peb nce, yog li tsim nyog kho qhov koob tshuaj yuav tsim nyog.

Tsis tas li, kev hloov pauv ntawm kev noj tshuaj, kev noj haus thiab kev tawm dag zog lub cev thaum lub sijhawm lactation.

Yog tias qhov kev npaj tshuaj insulin no tsim nyog rau tus neeg mob ntshav qab zib mellitus, tom qab ntawd tshuaj xyuas txog Humulin M3, raws li txoj cai, yog qhov zoo. Raws li cov neeg mob, cov tshuaj no zoo heev thiab ua tau siv tsis muaj kev phiv.

Nws yog ib qho tseem ceeb heev uas yuav tsum nco ntsoov tias nws yog txwv tsis pub sau ntawv rau cov tshuaj insulin rau koj tus kheej, nrog rau hloov mus rau lwm tus.

Ib lub raj mis ntawm Humulin M3 nrog ib qhov ntim ntawm 10 ml nqi ntawm 500 txog 600 rubles, ib pob khoom ntawm tsib 3 ml cartridges nyob rau hauv thaj tsam ntawm 1000-1200 rubles.

Luv luv insulin

Qhov muaj pes tsawg leeg ntawm cov tshuaj no suav nrog kev daws teeb meem tshuaj hormonal, uas tsis muaj cov tshuaj ntxiv uas ua kom ntev nws cov nyhuv hauv lub cev. Ib pawg ntawm cov yeeb yam luv luv ua haujlwm sai dua li lwm tus, tab sis tag nrho lub sijhawm ntawm lawv cov haujlwm yog luv.

Cov tshuaj Intramuscular muaj nyob rau hauv cov iav vials kaw, ntim nrog nres nres nrog txhuas ua.

Cov nyhuv ntawm cov insulin luv luv ntawm lub cev yog los ntawm:

kev tsuj lossis kev txhawb nqa qee yam ntawm cov enzymes,
kev ua kom tiav ntawm kev ua ke ntawm glycogen thiab hexokinase,
kev tiv thaiv ntawm lipase ua kom muaj roj ntau.

Qhov qib ntawm kev zais pa thiab biosynthesis yog nyob ntawm cov piam thaj hauv cov ntshav. Nrog rau qhov nce ntxiv hauv nws cov qib, cov txheej txheem ntawm cov tshuaj insulin ntau hauv cov txiav ua ke nce thiab, hloov pauv, nrog qhov kev poob qis hauv kev zais, kev zais cia qeeb.

Luv luv Insulin Txwv

Raws li lub sij hawm cov yam ntxwv ntawm kev tsim yeeb yam luv luv yog:

Cov tshuaj insulins luv luv (soluble, regulating) - ua tom qab kev tswj hwm tom qab ib nrab ib teev, yog li lawv pom zoo kom siv 40-50 feeb ua ntej noj mov. Qhov kev cia siab tshaj plaws ntawm cov tshuaj nquag hauv cov ntshav ntws tau mus txog tom qab 2 teev, thiab tom qab 6 teev tsuas yog ib qhov cim ntawm cov tshuaj nyob hauv lub cev. Cov insulins luv luv suav nrog tib neeg lub soluble txhob kaw, cov tib neeg soluble semisynthetic thiab monocomponent soluble nqaij npuas.
Ultrashort (sib raug rau tib neeg, analog) insulins - pib cuam tshuam rau lub cev tom qab kev coj noj coj ua tom qab 15 feeb. Kev ua tiav cov pob tw tseem tau tiav tom qab ob peb teev. Kev tshem tawm tiav ntawm lub cev tshwm sim tom qab 4 teev. Vim tias qhov tseeb tias ultrashort insulin muaj cov nyhuv ntawm lub cev ntau dua, cov kev npaj hauv nws muaj peev xwm siv tau 5-10 feeb ua ntej noj mov lossis tam sim ntawd tom qab noj mov. Hom tshuaj no tuaj yeem suav nrog tshuaj insine thiab ib nrab hluavtaws sib piv ntawm tib neeg cov tshuaj insulin.

Rov qab mus rau txheem

Luv luv insulin rau ntshav qab zib

Ntshav qab zib insulin pab tiv thaiv kev txhim kho ntawm cov kev mob nyhav, ua rau lub neej ntev dua ntawm cov ntshav qab zib thiab txhim kho nws qhov zoo. Tsis tas li, kev txhaj tshuaj ntawm cov tshuaj no txo cov load ntawm tus txiav, uas pab txhawb rau qee feem kho tshiab ntawm cov hlwb.

Cov txiaj ntsig zoo ib yam tuaj yeem ua tiav nrog hom 2 mob ntshav qab zib nrog kev ua haujlwm tseeb ntawm kev kho mob thiab ua raws li kev tswj hwm pom zoo los ntawm kws kho mob. Beta cell rov qab los kuj tseem muaj tus mob ntshav qab zib hom 1 tsuas yog kev kuaj mob raws sij hawm thiab ntsuas kev kho yam tsis ncua.

Tus mob ntshav qab zib yuav tsum muaj dab tsi? Tshawb xyuas peb cov ntawv qhia zaub mov noj txhua lub lim tiam tam sim no!

Feem ntau, cov tshuaj yog muab tshuaj intramuscularly lossis subcutaneously nrog tus qauv tsim tshwj xeeb rau cov tshuaj insulin. Tsuas yog nyob rau ntawm qhov muaj mob ntshav qab zib ua kom tsis nco qab, tso siab rau kev tswj hwm ntawm cov tshuaj yog kev tso cai. Cov koob tshuaj yog xaiv tau ntawm tus kheej, noj mus rau hauv tus account qhov mob hnyav, qib ntawm cov piam thaj hauv lub cev thiab qhov mob ntawm tus neeg mob.

Rov qab mus rau txheem

Cov Kev Phom Sij Hawm thiab Tshuaj Tiv Thaiv

Qhov tshwm sim tsis zoo tom qab kev tswj hwm ntawm tus neeg sawv cev hormonal tshwm sim thaum cov lus pom zoo muab tshuaj tsis ua raws. Qhov no nrog los ntawm qhov nce ntxiv ntawm insulin hauv cov ntshav khiav.

Feem ntau cov kev mob tshwm sim muaj xws li:

feem ntau tsis muaj zog
nce tawm hws,
lub plawv dhia
nce salivation,
kiv taub hau.

Thaum muaj mob hnyav yuav ua rau lub cev muaj mob ntau ntxiv rau hauv cov hlab ntshav (yog tias tsis muaj lub sijhawm tswj hwm cov zaub mov carbohydrates), kev huam yuaj tuaj yeem tshwm sim, nrog rau kev tsis nco qab thiab ua rau lub cev tsis nco qab lawm.

Rov qab mus rau txheem

Kev npaj tshuaj insulin luv thiab ultrafast

Txhua yam tshuaj uas muaj luv luv tib neeg insulins lossis lawv cov analogues muaj cov yam ntxwv zoo sib xws. Yog li no, yog tias tsim nyog, lawv tuaj yeem hloov, soj ntsuam cov tshuaj kho mob tib yam, nrog kev sib tham ua ntej ntawm kws kho mob yuav tsum ua. Yog li, kev xaiv me me ntawm kev ua haujlwm luv thiab ua haujlwm sai insulin npe

Cov txheej txheem ntawm kev ua ntawm insulin Humulin NPH

Cov nyhuv pharmacological yog qhov txo qis hauv cov ntshav qab zib vim muaj kev cuam tshuam ntau ntxiv nws mus rau hauv cov hlwb thiab cov nqaij siv Humulin NPH. Hauv cov kab mob ntshav qab zib mellitus, kev tsim tawm ntawm pancreatic insulin hormone yog txo, uas yuav tsum muaj kev hloov kho hormone. Cov tshuaj tsub kom ntxiv cov ntshav qabzib siv los ntawm cov hlwb uas xav tau zaub mov noj. Cov tshuaj Insulin cuam tshuam nrog cov receptors tshwj xeeb rau ntawm lub ntsej muag ntawm tes, uas ua rau muaj ntau cov txheej txheem biochemical, uas suav nrog, tshwj xeeb, kev tsim ntawm hexokinase, pyruvate kinase, glycogen synthetase. Kev thauj mus los ntawm cov piam thaj mus rau cov ntaub so ntswg los ntawm cov ntshav nce, qhov twg nws yuav tsawg dua.

Cov chaw muag tshuaj

Tus txheej txheem kho pib ib teev tom qab txhaj tshuaj.
Cov suab thaj txo cov nyhuv ntev li 18 teev.
Qhov txiaj ntsig zoo tshaj plaws yog tom qab 2 teev thiab txog 8 teev los ntawm lub sijhawm tswj hwm.

Xws li cov kev hloov hauv lub caij nyoog ntawm cov kev ua yeeb tshuaj yog nyob ntawm qhov chaw tswj hwm ntawm kev ncua thiab lub cev muaj zog ntawm tus neeg mob. Cov khoom no yuav tsum tau coj mus rau hauv qhov kev txiav txim thaum muab cov tshuaj ntau npaum li cas thiab kev tswj hwm ntau zaus. Muab lub caij nyoog ntev ntawm cov nyhuv, Humulin NPH raug kho ua ke nrog insulin luv thiab ultrashort.

Kev faib khoom thiab tawm ntawm lub cev:

Insulin Humulin NPH tsis nkag rau hauv hematoplacental teeb meem thiab tsis nthuav tawm los ntawm cov qog mammary nrog kua mis.
Inactivated nyob rau hauv daim siab thiab ob lub raum dhau los ntawm enzyme insulinase.
Kev tshem tawm cov tshuaj tsuas yog dhau ntawm ob lub raum.

Cov kev tsis haum lub ntsej muag suav nrog:

Kev mob ntshav qog ntshav yog qhov phom sij txaus ntshai nrog kev noj tshuaj tsis txaus. Qhia los ntawm kev tsis nco qab, uas tuaj yeem tsis meej pem nrog hyperglycemic coma,
kev ua xua rau ntawm qhov chaw txhaj tshuaj (liab liab, khaus, o),
zawm caj pas
txog siav
hypotension
urticaria
tachycardia
lipodystrophy - lub zos atrophy ntawm subcutaneous rog.

Cov kev cai dav dav ntawm kev siv

Cov tshuaj yuav tsum tau txhaj nyob hauv qab ntawm daim tawv nqaij ntawm lub xub pwg, lub duav, pob tw los yog sab hauv plab phab ntsa, thiab qee zaum txhaj tshuaj intramuscular tseem muaj peev xwm.
Tom qab txhaj tshuaj, koj yuav tsum tsis txhob nias thiab zaws thaj tsam ntxeem tau zoo.
Nws yog txwv tsis pub siv cov tshuaj hla dej.
Cov koob tshuaj yog xaiv ib tus zuj zus los ntawm tus kws kho keeb (endocrinologist) thiab raws li kev soj ntsuam ntshav qab zib.

Algorithm rau cov tshuaj insulin Humulin NPH

Humulin hauv vials ua ntej siv yuav tsum tau muab sib xyaw los ntawm dov lub vial ntawm xib teg kom txog thaum cov xim ntawm mis tuaj. Tsis txhob co, ua npuas dej, lossis siv cov tshuaj insulin nrog cov pob zeb uas ci rau ntawm lub khob ntsa.
Humulin NPH hauv daim cartridges tsis tsuas yog txav nruab nrab ntawm xib teg, rov ua dua 10 zaug txav, tab sis kuj sib xyaw, maj mam tig lub taub hau. Nco ntsoov tias insulin npaj txhij rau kev tswj hwm los ntawm kev ntsuam xyuas kom xwm yeem thiab xim. Yuav tsum muaj cov ntsiab lus tsis sib xws hauv cov xim mis. Tsis tas li tsis txhob tshee lossis ua npuas dej siv tshuaj. Tsis txhob siv cov tshuaj nrog cereal lossis sediment. Lwm cov tshuaj insulins tsis tuaj yeem raug txhaj rau hauv daim cartridge thiab tsis tuaj yeem muab tshuaj ntxiv.
Cov xaum xaum muaj 3 ml ntawm insulin-isophan ntawm koob tshuaj 100 IU / ml. Rau 1 txhaj tshuaj, nkag mus tsis tshaj 60 IU. Cov cuab yeej tso cai noj kom haum nrog qhov tseeb txog li 1 IU. Nco ntsoov tias rab koob tau nruj nreem txuas rau hauv lub cuab yeej.

- Ntxuav tes siv xab npum ntxuav, thiab tom qab ntawd kho lawv nrog tshuaj tua kab mob.

- Txiav txim siab rau ntawm thaj chaw txhaj tshuaj thiab kho cov tawv nqaij nrog cov tshuaj antiseptic.

- Lwm qhov chaw txhaj tshuaj kom qhov chaw qub siv tsis ntau tshaj li ib zaug ib hlis.

Nta ntawm daim ntawv thov cov koob txhaj tshuaj ntaus

Tshem lub hau los ntawm rub nws tawm dua li tig nws.
Kuaj cov tshuaj insulin, txee lub neej, qauv thiab xim.
Npaj ib rab koob txhaj koob raws li tau piav los saum no.
Ntsia tus pas kom txog rau thaum nws nruj.
Tshem ob lub hau tawm ntawm rab koob. Sab nraud - tsis txhob muab pov tseg.
Kuaj cov tshuaj insulin.
Quav ntawm daim tawv nqaij thiab txhaj rab koob hauv qab daim tawv nqaij ntawm kaum ntawm 45 degrees.
Qhia cov tshuaj insulin los ntawm kev tuav lub pob nrog lub ntiv tes kom txog thaum nws nres, suav qeeb qeeb rau 5.
Tom qab tshem tawm rab koob, tso lub pob cawv ntawm qhov chaw txhaj tshuaj tsis tas txhuam los yog tawv nqaij. Feem ntau, poob qis ntawm cov tshuaj insulin tuaj yeem nyob ntawm lub taub hau ntawm rab koob, tab sis tsis xau los ntawm nws, uas txhais tau tias yog koob tshuaj tsis tiav.
Kaw lub koob nrog lub hau sab nraud thiab pov tseg ntawm nws.

Muaj peev xwm cuam tshuam nrog lwm cov tshuaj

Cov tshuaj uas txhim kho cov nyhuv ntawm Humulin:

qab zib-txo cov ntsiav tshuaj,
tshuaj tiv thaiv kev nyuaj siab - monoamine oxidase inhibitors,
hypotonic tshuaj los ntawm cov pab pawg ntawm ACE inhibitors thiab beta blockers,
carbonic anhydrase inhibitors,
imidazoles
tetracycline tshuaj tua kab mob,
lithium npaj
B vitamins,
theophylline
haus cawv muaj tshuaj.

Cov tshuaj uas inhibit qhov kev txiav txim ntawm insulin Humulin NPH:

tshuaj noj tiv thaiv tsis pub muaj menyuam
glucocorticosteroids,
cov thyroid hormones
tshuaj kho mob
tricyclic cov tshuaj tiv thaiv kab mob,
cov neeg sawv cev uas qhib txoj kev kho mob hlwb,
calcium channel blockers,
tshuaj yeeb qaug cawv.

Cov cim ntawm Humulin

Lub npe Kev Lag Luam	Chaw tsim tshuaj paus
Insuman Bazal	Sanofi-Aventis Deutschland GmbH, (Lub Teb Chaws Yelemees)
Protafan	Novo Nordisk A / S, (Tebchaws Denmark)
Berlinsulin N Basal U-40 thiab Berlisulin N Basal Cwj mem	Berlin-Chemie AG, (Lub Tebchaws Yelemees)
Actrafan HM	Novo Nordisk A / O, (Denmark)
Br-Insulmidi ChSP	Bryntsalov-A, (Russia)
Neej Neeg B	Indar Insulin CJSC, (Tebchaws Ukraine)
Isofan Insulin Ntiaj Teb Khob	AI CN Galenika, (Yugoslavia)
Homofan	Pliva, (Croatia)
Biogulin NPH	Bioroba SA, (Brazil)

Tshuaj xyuas cov tshuaj insulin-isophan tshuaj tiv thaiv kab mob:

Kuv xav ua qhov kev txhim kho - nws yog txwv tsis pub tswj cov tshuaj insulin ntev ntev!

Dab tsi yog Humulin?

Niaj hnub no, lub sij hawm Humulin tuaj yeem pom nyob rau hauv cov npe ntawm ntau cov tshuaj tsim los txo cov ntshav qab zib - Humulin NPH, MoH, Ntu thiab Ultralent.

Qhov sib txawv hauv cov txheej txheem rau kev tsim cov tshuaj no muab txhua cov piam thaj ua kom tsawg nrog nws tus yam ntxwv. Qhov zoo tshaj yuav coj mus rau hauv kev suav tshuaj thaum kho kev kho mob rau cov neeg muaj ntshav qab zib. Ntxiv rau cov tshuaj insulin (lub ntsiab tseem ceeb, ntsuas hauv IU), cov tshuaj muaj cov neeg tsis paub qab hau, xws li kua tsis huv, protamines, carbolic acid, metacresol, zinc oxide, sodium hydroxide, thiab lwm yam.

Cov tshuaj tua kab mob pancreatic tau ntim rau hauv daim cartridges, vials, thiab koob txhaj tshuaj. Cov lus qhia txuas nrog qhia txog cov yam ntxwv ntawm kev siv tshuaj ntawm tib neeg. Ua ntej siv, cartridges thiab vials yuav tsum tsis txhob tshee muaj zog; txhua yam uas tsim nyog rau kev rov ua kom tiav ntawm cov kua yog yob lawv ntawm lub xib teg ntawm txhais tes. Qhov yooj yim tshaj plaws rau kev siv los ntawm cov kws kho ntshav qab zib yog cov xaum xaum qhuav.

Kev siv cov tshuaj uas tau hais txog kev tso cai rau kev ua tiav kev kho mob rau cov neeg mob ntshav qab zib, vim lawv pab txhawb qhov hloov ntawm qhov tsis muaj txhij txhua thiab cov txheeb ze tsis txaus ntawm cov tshuaj endogenous ntawm cov txiav. Sau ntawv rau Heulin (noj ntau npaum, tshuaj noj) yuav tsum yog kws tshuaj endocrinologist. Yav tom ntej, yog tias tsim nyog, tus kws kho mob tuaj koom tuaj yeem kho qhov tseeb ntawm kev kho mob.

Ntawm ntshav qab zib ntawm thawj hom, insulin yog kho rau tus neeg rau lub neej. Nrog cov kev mob tshwm sim ntawm tus mob ntshav qab zib hom 2, uas nrog cov mob hnyav nrog kab mob sib kis, kev kho yog tsim los ntawm cov chav kawm ntawm cov sib txawv. Nws yog ib qho tseem ceeb kom nco ntsoov tias nrog ib tus kab mob uas yuav tsum muaj kev qhia txog khoom neeg tsim tshuaj lom neeg rau hauv lub cev, koj tsis tuaj yeem tsis lees txais cov kev kho mob insulin, txwv tsis pub lub txim hnyav tsis tuaj yeem zam tau.

Tus nqi ntawm cov tshuaj ntawm pab pawg no pharmacological nyob ntawm lub sijhawm ntawm kev ua thiab hom ntim. Tus nqi kwv yees nyob rau hauv lub fwj pib los ntawm 500 rubles., Tus nqi nyob rau hauv daim cartridges - los ntawm 1000 rubles., Hauv koob txhaj tshuaj yog tsawg kawg 1500 rubles.

Txhawm rau txiav txim qhov ntau npaum li cas thiab lub sijhawm noj tshuaj, koj yuav tsum hu rau tus kws endocrinologist

Nws tag nrho yog nyob ntawm ntau yam

Cov hom nyiaj thiab cov nyhuv ntawm lub cev tau piav qhia hauv qab no.

Cov tshuaj yog tsim los siv qhov siv DNA thev naus laus zis technology thiab muaj lub sij hawm ua nruab nrab. Lub hom phiaj tseem ceeb ntawm cov tshuaj yog tswj cov metabolism hauv qabzib. Pab inhibit cov txheej txheem ntawm cov protein piam thiab muaj cov nyhuv anabolic rau lub cev nqaij. Humulin NPH nce kev ua haujlwm ntawm cov enzymes uas txhawb kev tsim cov glycogen hauv cov leeg nqaij. Nws nce qhov ntim ntawm fatty acids, cuam tshuam rau qib ntawm glycerol, txhim kho cov protein ntau thiab txhawb kev noj cov aminocarboxylic acids los ntawm cov leeg hlwb.

Ib qho piv txwv uas txo cov ntshav qab zib yog:

Actrafan NM.
Diafan ChSP.
Insulidd N.
Protafan NM.
Neej Neeg B.

Tom qab txhaj tshuaj, cov tshuaj pib ua tom qab 1 teev, cov nyhuv tag nrho tiav nyob rau hauv 2-8 teev, cov tshuaj yeeb yam tseem ua haujlwm ntev li 18-20 teev. Lub sijhawm sijhawm rau kev txiav txim siab ntawm cov tshuaj hormones yog nyob ntawm cov koob tshuaj siv, thaj chaw txhaj tshuaj, thiab tib neeg yam haujlwm.

Humulin NPH yog qhia rau kev siv hauv:

Mob ntshav qab zib nrog cov tshuaj insulin pom zoo.
Thawj kuaj pom mob ntshav qab zib.
Cov poj niam cev xeeb tub uas muaj ntshav qab zib tsis muaj tshuaj insulin.

Cov kev qhia tau hais tias cov tshuaj tsis raug sau rau cov neeg muaj ntshav siab qis tam sim no, uas yog tus yam ntxwv ntshav tsawg dua 3,5 mmol / l, nyob rau hauv cov ntshav nruab nrab - 3.3 mmol / l, rau cov neeg mob uas lub cev tsis muaj lub cev tiv thaiv tsis haum rau ib qho tshuaj ntawm cov tshuaj.
Cov kev mob tshwm sim uas yuav tshwm sim tom qab siv cov tshuaj feem ntau manifested:

Kev ntshav siab.
Lub ntsej muag rog.
Kev tsis haum rau cov kab mob thiab hauv zos.

Raws li rau kev haus ntau dhau ntawm cov tshuaj, tsis muaj cov cim qhia tshwj xeeb ntawm kev haus ntau dhau. Cov tsos mob tseem ceeb tau suav hais tias yog qhov pib ntawm lub qog ntshav qab zib. Tus mob yog nrog mob taub hau, tachycardia, hws hws tawm hws thiab ntsej muag tawv nqaij. Txhawm rau zam qhov teeb meem kev noj qab haus huv zoo li no, tus kws kho mob xaiv cov tshuaj rau txhua tus neeg mob ib tus zuj zus, suav nrog qib glycemia.

Nrog kev noj ntau dhau ntawm cov tshuaj, hypoglycemia yuav tshwm sim.

Humulin-m3

Humulin M3, zoo li kev kho dhau los, yog ib qho ua ke tau ntev. Nws pom tau hais hauv daim ntawv ntawm ob-ncua kev ncua, iav daim iav muaj insulin humulin tsis tu ncua (30%) thiab humulin-nph (70%). Lub hom phiaj tseem ceeb ntawm Humulin Mz yog los tswj cov metabolism hauv qabzib.

Cov tshuaj pab tsim cov leeg, sai sai muab cov kua nplaum thiab aminocarboxylic acids rau hauv cov leeg ntawm cov leeg thiab lwm cov nqaij mos dua li lub hlwb. Humulin M3 pab nyob rau hauv daim siab hloov ua piam thaj rau glycogen, inhibits gluconeogenesis thiab hloov cov piam thaj ntau dhau mus ua subcutaneous thiab visceral rog.

Cov tshuaj ntawm cov tshuaj yog:

Protafan NM.
Yawg Hlob.
Actrapid Flekspen.
Xaus Optiset.

Tom qab txhaj tshuaj, Humulin M3 pib ua yeeb yam tom qab 30-60 feeb, qhov ua tiav siab tshaj plaws tau tiav hauv 2-12 teev, lub sijhawm ntawm kev ua haujlwm ntawm insulin yog 24 teev. Qhov xwm txheej cuam tshuam txog qib kev ua haujlwm ntawm Humulin m3 yog txuam nrog thaj chaw xaiv ntawm kev txhaj tshuaj thiab tshuaj, nrog kev ua haujlwm ntawm tus neeg thiab nws noj mov.

Cov neeg muaj ntshav qab zib uas xav tau kev kho insulin.
Cov poj niam cev xeeb tub uas muaj ntshav qab zib gestational.

Cov tshuaj nruab nrab cov tshuaj insulin yog qhov cuam tshuam hauv kev kuaj pom kev mob ntshav qab zib thiab kev tiv thaiv tsis haum rau cov khoom xyaw ntawm cov tshuaj muaj pes tsawg leeg. Kev kho tshuaj Insulin yuav tsum tau ua nyob rau hauv kev saib xyuas ntawm kws kho mob, uas yuav tshem tawm txoj kev txhim kho thiab cov kev mob ntawm kev mob ntshav qab zib, uas tuaj yeem dhau los, qhov zoo tshaj plaws, ua rau muaj kev nyuaj siab thiab ploj ntawm qhov tsis nco qab, hauv qhov phem tshaj - qhov pib ntawm kev tuag.

Thaum lub sij hawm kho tshuaj insulin, cov neeg mob yuav muaj kev tsis haum tshuaj hauv zos, uas feem ntau pom tshwm los ntawm khaus, tshem tawm, lossis o ntawm daim tawv nqaij ntawm qhov chaw txhaj tshuaj.Cov tawv nqaij raug mob li qub nyob hauv 1-2 hnub, nyob rau hauv cov teeb meem nyuaj ob peb lub lis piam yuav tsum ua. Qee zaum cov tsos mob no yog qhov qhia pom ntawm kev txhaj tshuaj tsis yog.

Kev tsis haum rau lub cev muaj tshwm sim me ntsis, tab sis nws cov yam ntxwv pom hnyav dua li yav dhau los, xws li khaus khaus, ua tsis taus pa, ntshav siab, tawm hws ntau thiab lub plawv dhia ceev. Hauv qee kis, kev fab tshuaj tuaj yeem ua rau muaj kev phom sij rau ib tus neeg lub neej, qhov xwm txheej raug kho los ntawm kev kho mob xwm txheej ceev, kev siv txoj kev tshem tawm thiab hloov tshuaj.

Cov tshuaj yog sau rau cov neeg xav tau kev pab insulin.

Humulin regula - ua yeeb yam luv luv

Humulin P yog cov DNA sib koom ua ke nrog sib xyaw nrog lub sijhawm luv luv. Lub hom phiaj tseem ceeb yog tswj hwm kev ua kom cov metabolism. Txhua txoj haujlwm tau muab rau cov tshuaj yog zoo li lub hauv paus ntsiab lus ntawm kev cuam tshuam rau lwm cov humulins. Kev daws yog qhia rau kev siv los ntawm cov neeg muaj kev mob ntshav qab zib mellitus ntawm hom thawj thiab thib ob, nrog lub cev tiv thaiv cov tshuaj tiv thaiv kab mob hauv lub qhov ncauj thiab kho kev sib txuas ua ke.
Humulin regula tshuaj yog:

Nrog cov ketoacidosis uas mob ntshav qab zib.
Ketoacidotic thiab hyperosmolar coma.
Yog tias mob ntshav qab zib tau tshwm sim thaum lub sijhawm nqa tus menyuam (raug rau cov zaub mov tsis qab).
Nrog kev sib quas ntus txoj kev kho mob ntshav qab zib nrog tus mob.
Thaum hloov mus rau cov tshuaj insulin txuas ntxiv.
Ua ntej kev phais mob, nrog cov teeb meem metabolic.

Humulin P yog contraindicated nyob rau hauv cov ntaub ntawv ntawm hypersensitivity rau ib tug neeg sib txuas ntawm cov tshuaj thiab tshuaj hypoglycemia. Tus kws kho mob ib leeg sau ib daim ntawv rau tus neeg mob ib koob tshuaj thiab koob txhaj tshuaj coj mus rau hauv tus lej ntawm cov piam thaj hauv cov ntshav ua ntej noj thiab tom qab 1-2 teev tom qab. Tsis tas li ntawd, nyob rau hauv chav kawm ntawm ib koob tshuaj, cov theem ntawm cov piam thaj hauv cov zis thiab cov chav kawm tshwj xeeb ntawm tus kabmob raug coj los siv.

Cov tshuaj yeeb yaj kiab uas tsis zoo, tsis zoo li yav dhau los, tuaj yeem muab tshuaj intramuscularly, subcutaneously thiab intravenously. Txoj kev siv ntau tshaj plaws ntawm kev tswj hwm yog subcutaneous. Hauv kev mob ntshav qab zib thiab cov ntshav qab zib tsis hnov qab, IV thiab IM txhaj tshuaj yog qhov xav tau. Nrog rau cov tshuaj monotherapy, cov tshuaj tau muab 3-6 zaug ib hnub. Txhawm rau tshem tawm qhov tshwm sim ntawm lipodystrophy, qhov chaw ntawm kev txhaj tshuaj hloov pauv txhua zaus.

Humulin P, yog tias tsim nyog, ua ke nrog cov tshuaj hormone ntawm qhov tshwm sim ntev. Cov tshuaj analogues nrov ntawm cov tshuaj:

Actrapid NM.
Biosulin R.
Insuman Ceev Heev GT.
Rosinsulin R.

Cov tshuaj tau sau tseg thaum hloov mus rau insulin txuas ntxiv

Tus nqi ntawm cov kev hloov pauv no pib ntawm 185 rubles, Rosinsulin yog suav tias yog cov tshuaj kim tshaj plaws, nws cov nqi hnub no dhau 900 rubles. Hloov cov insulin nrog ib qho tshuaj tiv thaiv kab mob yuav tsum muaj nrog kev koom tes ntawm tus kws kho mob uas tuaj koom. Qhov pheej yig tshaj plaws ntawm Humulin R yog Actrapid, nrov tshaj plaws yog NovoRapid Flekspen.

Kev ua yeeb yam ntev ntev Humulinultralente

Insulin Humulin ultralente yog lwm cov tshuaj qhia rau siv rau cov neeg mob uas muaj ntshav qab zib insulin-tiv thaiv kev mob ntshav qab zib. Cov khoom yog raws cov DNA recombinant thiab yog cov khoom siv tau ua haujlwm ntev. Qhov kev ncua yog qhib kom ua haujlwm tom qab peb teev tom qab txhaj, qhov txiaj ntsig siab tshaj plaws tau tiav hauv 18 teev. Cov lus qhia rau kev siv qhia tias lub sijhawm siab tshaj plaws ntawm Humulinultralente yog 24-28 teev.

Tus kws kho mob teeb tsa qhov muab tshuaj rau txhua tus neeg mob ib tus zuj zus, suav nrog tus neeg mob tus mob. Cov tshuaj yog muab tshuaj tsis muaj hwj chim, txhaj tshuaj yog sib sib zog nqus rau hauv daim tawv nqaij 1-2 zaug hauv ib hnub. Thaum Humulin Ultralente muab tso ua ke nrog lwm cov tshuaj lom neeg, qhov kev txhaj tshuaj tam sim ntawd. Kev xav tau cov tshuaj insulin ntau ntxiv yog tias ib tus neeg mob, ntsib kev ntxhov siab, noj tshuaj tiv thaiv qhov ncauj, glucocorticoids lossis thyroid cov tshuaj hormones.Thiab, ntawm qhov tsis sib xws, nws txo qis nrog cov kab mob ntawm daim siab thiab lub raum, thaum noj MAO inhibitors thiab beta-blockers.
Cov tshuaj ntawm cov tshuaj: Humodar K25, Gensulin M30, Insuman Comb thiab Farmasulin.

Xav txog contraindications thiab phiv.

Zoo li txhua yam ntawm humulins, insulin ultralente yog qhov pom tseeb yog qhov ua rau nws lub cev tsis muaj zog thiab ua rau muaj kev cuam tshuam rau cov khoom sib txawv ntawm cov khoom. Raws li cov kws tshaj lij, ib qho kev cuam tshuam tsis tshua muaj tshwm sim nws tus kheej yog kev tawm tsam. Ib qho tshwm sim tau tom qab kev txhaj tshuaj yog ua kom pom los ntawm lipodystrophy, nyob rau hauv uas tus nqi ntawm adipose nqaij hauv cov nqaij mos subcutaneous poob, thiab insulin tsis kam.

Tsawg tsawg zaus, cov yeeb tshuaj ua rau muaj kev fab tshuaj.

Ib qho nrov ntawm cov tshuaj lom ntawm humulin - Protaphane

Insulin Protafan NM yog qhia rau cov ntshav qab zib mellitus ntawm hom thawj thiab thib ob, rau kev tiv thaiv ntawm sulfonylurea derivatives, rau cov kab mob ua rau mob ntshav qab zib, hauv kev phais mob thiab tom qab hloov kho, rau cov poj niam cev xeeb tub.

Protafan tau muab tshuaj rau txhua tus neeg mob ntawm tus kheej, suav nrog qhov xav tau ntawm nws lub cev. Raws li cov lus qhia, qhov xav tau rau qhov koob tshuaj qog ntawm qhov tshuaj hormones yog 0.3 - 1 IU / kg / hnub.

Qhov kev xav tau nce ntxiv hauv cov neeg mob uas muaj insulin tsis kam (tsis hnov qab cov teeb meem ntawm cov cell mus rau insulin), feem ntau qhov no tshwm sim nrog cov neeg mob thaum tiav nkauj tiav nraug thiab cov neeg muaj rog. Kev kho cov koob tshuaj tuaj yeem nqa los ntawm tus kws kho mob yog tias tus neeg mob txhim kho cov kab mob concomitant, tshwj xeeb yog hais tias tus kab mob kis tau. Qhov ntau npaum li cas yog kho rau cov kab mob ntawm lub siab, ob lub raum thiab kab mob ntawm cov thyroid caj pas. Protafan NM yog siv los ua kev txhaj tshuaj hauv cov tshuaj tua kab mob thiab hauv kev sib xyaw ua ke nrog cov insulins luv luv lossis ceev.

Hom thiab cov qauv ntawm kev tso tawm ntawm Humulin

Insulin Humulin yog ib yam tshuaj uas ua kom cov insulin ua tiav rau hauv tib neeg lub cev hauv cov qauv, qhov chaw ntawm cov amino acids thiab lub cev hnyav. Nws yog recombinant, uas yog, ua raws li txoj kev ntawm kev tshuaj ntsuam genetic engineering. Kev suav cov tshuaj ntawm cov tshuaj no tuaj yeem rov qab tau cov roj metabolism hauv cov neeg muaj ntshav qab zib thiab zam kom tsis txhob muaj teeb meem.

Hom Humulin:

Humulin Tsis tu ncua - Qhov no yog kev daws teeb meem ntawm cov tshuaj insulin, hais txog kev siv yeeb yaj kiab luv luv. Nws lub hom phiaj yog pab cov suab thaj los ntawm cov ntshav kom nkag mus rau hauv cov cell, qhov chaw nws siv los ntawm lub cev rau lub zog. Nws feem ntau yog siv ua ke nrog insulin hauv nruab nrab lossis ntev ntev. Nws tuaj yeem siv tau ib leeg yog tias tus neeg mob ntshav qab zib muaj lub tshuab ntxig ntxig rau dej.
Humulin NPH - raug tshem tawm ua los ntawm tib neeg cov kua dej thiab cov tshuaj sulfate. Ua tsaug rau qhov kev txhawb ntxiv no, cov nyhuv ntawm cov piam thaj muaj txiaj ntsig pib qeeb dua li cov insulin luv luv, thiab siv sijhawm ntev dua. Ob qho kev tswj hwm ib hnub txaus txaus rau kev noj haus glycemia thaum noj mov. Ntau zaus, Humulin NPH raug kho nrog rau insulin luv luv, tab sis nrog ntshav qab zib hom 2 nws tuaj yeem siv tau ntawm nws tus kheej.
Humulin M3 Qhov no yog ob-theem npaj muaj 30% insulin Tsis tu ncua thiab 70% - NPH. Tsawg feem ntau pom ntawm muag Humulin M2, nws muaj qhov sib piv ntawm 20:80. Vim tias qhov tseeb tias qhov kev faib ua feem ntawm cov tshuaj hormones yog tsim los ntawm cov chaw tsim khoom thiab tsis coj mus rau tus neeg mob cov kev xav tau ntawm tus neeg mob, ntshav qab zib nrog nws cov kev pab tsis tuaj yeem tswj tau zoo li thaum siv luv thiab nruab nrab insulin cais. Humulin M3 tuaj yeem siv los ntawm cov neeg mob ntshav qab zib, uas pom zoo rau kev coj noj coj ua ntawm kev kho mob insulin.

Cov lus qhia kom ntev:

Neeg lim hiam	Cov sijhawm ua haujlwm
Neeg lim hiam	thaum pib	siab tshaj plaws	qhov kawg
Ntxawg	0,5	1-3	5-7
NPH	1	2-8	18-20
M3 thiab M2	0,5	1-8,5	14-15

Tag nrho cov tshuaj humulin tam sim no tsim los ntawm Humulin muaj qhov ua kom siab ntawm U100, yog li nws tsim nyog rau niaj hnub insulin koob txhaj tshuaj thiab koob txhaj tshuaj.

Cov Ntawv Tso Tawm:

10 ml iav vials
cartridges rau syringe cwjmem, muaj 3 ml, hauv ib pob ntawm 5 daim.

Humulin insulin yog muab tshuaj subcutaneously, hauv qhov xwm txheej hnyav - intramuscularly. Kev tswj hwm kev noj qab haus huv tsuas yog tso cai rau Humulin Tsis tu ncua, nws yog siv los tshem tawm qhov mob siab phem thiab yuav tsum tau nqa tawm tsuas yog nyob hauv kev saib xyuas neeg mob.

Kev taw qhia thiab contraindications

Raws li cov lus qhia, Humulin tuaj yeem kho rau txhua tus neeg mob uas muaj cov tshuaj insulin tsis txaus. Feem ntau pom nyob hauv cov neeg muaj tus mob hom 1 lossis ntau dua 2 xyoos mob ntshav qab zib. Kev siv tshuaj insulin ib ntus yog ua tau thaum coj menyuam, txij li cov tshuaj txo qis qab zib raug txwv nyob rau lub sijhawm no.

Humulin M3 tsuas yog kho rau cov neeg mob neeg laus xwb, rau leej twg siv cov tshuaj insulin tswj hwm kev nyuaj yog qhov nyuaj. Vim tias qhov kev pheej hmoo ntawm kev mob ntshav qab zib ntau dua mus txog 18 xyoo, Humulin M3 tsis pom zoo.

Cov tshuaj phiv:

Kev mob ntshav siab vim lub cev muaj zog ntau dhau ntawm insulin, tsis muaj feem rau kev qoj ib ce, tsis muaj zaub mov carbohydrates hauv zaub mov.
Cov tsos mob ntawm kev ua xua, xws li ua pob xoo, khaus, khaus thiab liab ib ncig ntawm qhov chaw txhaj tshuaj. Lawv tuaj yeem tshwm sim los ntawm tib neeg cov tshuaj insulin thiab ntu sib txuam ntawm cov tshuaj. Yog tias kev ua xua nyob rau hauv ib lub lis piam, Humulin yuav tau hloov nrog cov tshuaj insulin nrog cov sib txawv.
Cov leeg mob los yog mob plab, ua kom lub plawv muaj zog tuaj yeem tshwm sim thaum tus neeg mob tsis txaus cov poov tshuaj. Cov tsos mob ploj tom qab tshem tawm qhov tsis txaus ntawm cov macronutrient no.
Hloov pauv qhov tuab ntawm daim tawv nqaij thiab cov nqaij mos subcutaneous ntawm qhov chaw txhaj tshuaj ntau dhau.

Tsum cov kev siv tshuaj insulin tsis tu ncua yog qhov txaus ntshai, yog li, txawm tias qhov tsis xis nyob, kev kho tshuaj insulin yuav tsum txuas ntxiv mus kom txog thaum tham nrog koj tus kws kho mob.

Feem ntau cov neeg mob uas tau qhia Humulin tsis ntsib kev mob tshwm sim dua li kev mob ntshav qab zib tsawg.

Humulin - cov lus qhia rau kev siv

Kev suav qhov ntsuas, kev npaj rau kev txhaj tshuaj thiab kev tswj hwm ntawm Humulin yog qhov zoo ib yam li lwm cov tshuaj insulin ntawm cov sijhawm ua haujlwm zoo sib xws. Qhov txawv tsuas yog nyob rau lub sijhawm ua ntej noj movCov. Nyob rau hauv Humulin Li Ntev nws yog 30 feeb. Nws yog qhov tsim nyog los npaj rau kev tswj hwm tus kheej ntawm cov tshuaj hormones ua ntej, ua tib zoo nyeem cov lus qhia rau kev siv.

Kev npaj

Cov tshuaj insulin yuav tsum tau muab tshem tawm hauv lub tub txias ua ntej kom ntsuas kub ntawm qhov kev daws teeb meem ntes tau nrog chavCov. Lub taub hau los yog lub raj mis uas sib xyaw ntawm cov tshuaj hormones nrog cov tshuaj tiv thaiv (Humulin NPH, Humulin M3 thiab M2) yuav tsum tau muab nruab nrab ntawm cov xib teg ob peb zaug thiab tig mus thiab nqis kom lub txim nyob hauv qab yog yaj tag thiab qhov kev ncua ntawv tau txais cov xim tsis sib thooj yam tsis muaj kev cuam tshuam. Muab nws sib zog ua kom tsis txhob muaj qhov tsau ntau ntawm qhov kev ncua ntawv nrog cua. Humulin Qhov tsis tu ncua tsis xav tau kev npaj zoo li no, nws yog ib txwm pob tshab.

Qhov ntev ntawm rab koob yog xaiv nyob rau hauv xws li txoj hauv kev kom paub meej subcutaneous txhaj tshuaj thiab tsis nkag mus rau hauv cov leeg. Cov koob txhaj tshuaj haum rau insulin Humulin - Humapen, BD-Cwj mem thiab lawv cov duab sib piv.

Cov tshuaj insulin raug txhaj rau hauv cov chaw uas muaj cov roj ntsha ua haujlwm: lub plab, tus ncej, pob tw thiab sab caj npab. Kev nqus nrawm tshaj plaws thiab teeb tsa rau hauv cov ntshav yog pom nrog kev txhaj tshuaj mus rau hauv lub plab, yog li Humulin Tsis tu ncua yog pricked muaj. Txhawm rau kom ua yeeb yam ntawm cov tshuaj kom ua raws li cov lus qhia, nws tsis tuaj yeem tso dag kom nce ntshav ncig ntawm qhov chaw txhaj tshuaj: txhuam, muab khuam, thiab ntxig rau hauv dej kub.

Thaum qhia txog Humulin, nws yog ib qho tseem ceeb kom tsis txhob maj: maj mam sau cov quav ntawm daim tawv nqaij tsis txhawm rau cov leeg nqaij, maj mam txhaj cov tshuaj, thiab tom qab ntawd tuav rab koob ntawm daim tawv nqaij rau ob peb feeb kom cov tshuaj no tsis pib xau. Txhawm rau txo txoj kev pheej hmoo ntawm lipodystrophy thiab o, cov koob tau hloov tom qab siv txhua zaus.

Lus ceebtoom

Thawj koob tshuaj Humulin yuav tsum tau xaiv nrog cov kws kho mob koom nrog. Kev noj tshuaj ntau dhau tuaj yeem ua rau kom cov ntshav qab zib poob qis thiab ua kom lub cev tsis tsaug zog.Qhov tsis txaus noj ntawm lub cev yog fraught nrog tus mob ntshav qab zib ketoacidosis, ntau yam angiopathies thiab neuropathy.

Ntau hom tshuaj insulin txawv nyob rau hauv cov hauj lwm zoo, yog li koj yuav tsum hloov ntawm Humulin mus rau lwm cov tshuaj tsuas yog muaj kev phiv los sis tsis them nyiaj txaus rau ntshav qab zib. Hloov chaw yuav tsum tau hloov dua siab tshiab koob tshuaj thiab ntxiv, ntau dua glycemic tswj.

Qhov xav tau rau insulin tuaj yeem nce ntxiv thaum lub cev hloov hauv hormonal hauv lub cev, thaum noj qee yam tshuaj, kis kab mob, kev ntxhov siab. Tsawg cov tshuaj hormones yog qhov tsim nyog rau cov neeg mob uas muaj kab mob siab thiab, tshwj xeeb, lub raum tsis ua haujlwm.

Cov kev cai humulin cia txoj cai

Txhua hom insulin xav tau qhov tshwj xeeb cia khoom. Cov yam ntxwv ntawm cov tshuaj hormones hloov pauv ntau thaum khov, kis los ntawm hluav taws xob ultraviolet thiab kub siab dua 35 ° C. Khoom seem yog muab tso rau hauv tub yees, hauv qhov rooj lossis ntawm txee ua kom deb ntawm lub qab phab ntsa. Txee lub neej raws li cov lus qhia rau kev siv: 3 xyoos rau Humulin NPH thiab M3, 2 xyoos rau Kev Nquag Hloov. Lub raj mis qhib yuav tuaj yeem nyob rau ntawm 15-25 ° C rau 28 hnub.

Cov nyhuv ntawm cov tshuaj ntawm humulin

Cov tshuaj noj tuaj yeem hloov qhov kev hloov pauv ntawm insulin thiab nce qhov kev pheej hmoo ntawm kev phiv. Yog li, thaum sau daim ntawv noj tshuaj rau lub cev, tus kws kho mob yuav tsum sau tag nrho cov tshuaj noj, suav nrog tshuaj ntsuab, vitamins, zaub mov noj, tshuaj pab txhawb nqa thiab kev noj tshuaj tiv thaiv.

Cov tau txais txiaj ntsig:

Ua rau lub cev	Sau cov tshuaj
Kev nce qab zib, nce ntxiv ntawm cov koob tshuaj insulin yog qhov yuav tsum tau ua.	Qhov ncauj tawm tsam, glucocorticoids, hluavtaws androgens, cov thyroid hormones, xaiv select2-adrenergic agonists, suav nrog cov tshuaj feem ntau terbutaline thiab salbutamol. Kev kho rau kab mob ntsws, nicotinic acid, lithium npaj. Thiazide diuretics siv los kho ntshav siab.
Qab zib txo. Txhawm rau kom tsis txhob mob hypoglycemia, cov koob tshuaj ntawm Humulin yuav tsum raug txo kom tsawg.	Tetracyclines, salicylates, sulfonamides, anabolics, beta-blockers, hypoglycemic cov neeg sawv cev rau kev kho mob ntshav qab zib hom 2. ACE inhibitors (xws li enalapril) thiab AT1 receptor blockers (losartan) feem ntau siv los kho ntshav siab.
Kev tsis tuaj yeem xav txog ntawm cov ntshav qab zib.	Cawv, pentacarinate, clonidine.
Txo cov tsos mob ntawm hypoglycemia, uas yog vim li cas nws nyuaj rau tshem tawm nws hauv sijhawm.	Beta blockers, piv txwv li, metoprolol, propranolol, qee qhov muag tee rau kev kho kab mob glaucoma.

Cov yam ntxwv ntawm kev siv thaum cev xeeb tub

Yuav kom zam kev xeeb tub ntawm tus me nyuam hauv plab thaum cev xeeb tub, nws tseem ceeb heev uas yuav tsum tau muaj tas li ntawm glycemia. Hypoglycemic tshuaj tsis zoo rau lub sijhawm no, txij li lawv cuam tshuam cov khoom noj rau tus menyuam. Qhov tsuas pub kho rau lub sijhawm no yog qhov ntev thiab luv insulin, suav nrog Humulin NPH thiab Ntu. Kev qhia ntawm Humulin M3 tsis tsim nyog, vim nws tsis muaj peev xwm them taus rau ntshav qab zib mellitus zoo.

Thaum cev xeeb tub, qhov xav tau kev hloov pauv ntau ntau zaug: nws txo qis hauv thawj peb hlis, nce ntau hauv 2 thiab 3, thiab poob qis heev tom qab yug menyuam. Yog li, txhua tus kws kho mob ua tus cev xeeb tub thiab yug menyuam yuav tsum ceeb toom txog qhov muaj ntshav qab zib hauv cov poj niam.

Siv tshuaj Insulin Humulin tuaj yeem siv tsis pub txwv thaum pub niam mis, vim nws tsis nkag rau hauv mis thiab tsis cuam tshuam rau cov ntshav qab zib ntawm tus menyuam.

Dab tsi tuaj yeem hloov Humulin insulin yog tias muaj kev cuam tshuam tshwm sim:

Tshuaj	Nqi rau 1 ml, tshiav.		Kev Tshaj Tawm	Nqi rau 1 ml, tshiav.
	lub raj mis	cwj mem cartridge		lub raj mis	daim cartridge
Humulin NPH	17	23	Biosulin N	53	73
			Insuman Bazal GT	66	—
			Tshuaj yaug NPH	44	103
			Protafan NM	41	60
Humulin Tsis tu ncua	17	24	Actrapid NM	39	53
			Rinsulin P	44	89
			Insuman Ceev Heev GT	63	—
			Biosulin P	49	71
Humulin M3	17	23	Mikstard 30 nm	Tam sim no tsis muaj
			Gensulin M30

Cov lus no tsuas yog ua tiav cov analogues - kev tsim kho ua kom muaj cov tib neeg cov insulins nrog rau kev ua haujlwm ntev.

Nco ntsoov kawm! Koj puas xav tias kev tswj hwm kev noj qab haus huv ntawm cov tshuaj thiab cov kua dej yog ib txoj kev los tswj cov piam thaj kom tswj? Tsis muaj tseeb! Koj tuaj yeem soj ntsuam qhov no koj tus kheej los ntawm kev pib siv nws. nyeem ntxiv >>

Thaum twg nws yog tshuaj?

Cov tshuaj "Humulin M3" yog tshuaj rau cov neeg mob ntshav qab zib xav tau kev kho tshuaj insulin, nrog rau cov ntshav qab zib hauv lub sijhawm, uas tshwm sim hauv cov pojniam thaum xeeb tub. Cov tshuaj pab hloov cov piam thaj rau glycogen thiab hloov suab thaj rau hauv cov rog, yog li txo txoj kev pheej hmoo ntawm gluconeogenesis. Ua ntej siv cov tshuaj lag luam, koj yuav tsum sab laj nrog tus kws kho mob uas yuav suav qhov tshuaj noj thiab ua lub sijhawm teem sijhawm.

Rov qab rau cov lus txheej txheem

Nws puas muaj peev xwm cev xeeb tub thiab lactating poj niam?

Cov kev qhia ntawm cov tshuaj tso cai rau kev siv ncua kev kawm ntawv txhawm rau kho cov piam thaj rau cov ntshav qab zib hauv nruab plab thaum lub sijhawm yoj tes. Sau ntawv kho mob thiab muab tshuaj yuav tsum yog kws kho mob. Cov tshuaj yuav pab txo cov kev pheej hmoo ntawm kev tsim pathologies ntawm cov plab hnyuv siab raum hauv lub cev thiab yuav pab niam yooj yim hloov lub sijhawm cev xeeb tub. Tsis muaj kev txwv thaum noj thaum lactation. Rau kev yooj yim ntawm kev siv tshuaj insulin, ib tug xaum xaum nrog cov kua roj av uas muaj cov tshuaj tov rau kev tswj hwm tau pom zoo rau cov niam yug.

Rov qab rau cov lus txheej txheem

Cov kev thaiv tsis zoo thiab cov tshwm sim

Cov yeeb tshuaj txwv tsis pub rau siv los ntawm cov neeg uas muaj lub siab tuab ntawm lub qog ntshav qab zib. 100 IU ntawm cov tib neeg cov tshuaj insulin rau 1 ml ntawm cov khoom lag luam tshuaj, uas, nrog txoj cai thiab qhov ntau thiab tsawg, tsis ua rau muaj kev phiv tshuaj, tsuas yog muaj qee tus neeg muaj qhov tsis haum rau cov tshuaj ntawm cov tshuaj. Yog tias lub cev tsis lees txais cov tshuaj, cov kev mob tshwm sim tsis zoo no tshwm sim:

Kev phiv tshuaj yuav yog cov tsos mob ntawm daim tawv nqaij.

nce hws
daim tawv nqaij mob, khaus, liab ntawm daim tawv nqaij,
txog siav
siab txo
tachycardia.

Lub sijhawm tiv thaiv ntawm cov kev mob tshwm sim tuaj yeem sib txawv. Txhawm rau kom tshem tawm qhov tsis xis nyob los ntawm cov tshuaj tiv thaiv ntshav qab zib tsawg, nws raug nquahu kom noj me me ntawm qab zib. Thaum cov tshuaj ua ke nrog cov tshuaj insulin ntev ntev, qhov tsis zoo ntawm kev haus ib ce ntaug maj mam tshwm sim thiab tuaj yeem tshwm sim tom qab 2-3 teev. Txhawm rau taug qab cov piam thaj thiab tsis txhob tshaj nws nrog suab thaj, koj yuav tsum siv cov nplaum los saib xyuas kev noj qab haus huv ntawm cov ntshav qab zib.

Rov qab rau cov lus txheej txheem

So haujlwm thiab chaw cia khoom

Cov tshuaj yuav yog tshwj xeeb los ntawm kws kho mob. Ampoule cartridges lossis vials tau pom zoo kom khaws cia hauv qhov chaw txias tsaus. lub tub yees yog qhov tsim nyog yog tias qhov ntsuas kub hauv nws khaws cia hauv 2-8 degrees. Kev daws yuav tsum tsis txhob txhuam. Lub crystallized ncua kev kawm tsis haum rau siv. Cov pob nyiaj qhib qhib tau tso cai siv rau 28 hnub, txuag tsis tau nkag mus rau lub teeb ntawm qhov kub ntawm 15 txog 26 degrees. Cov lus qhia pom zoo kom khaws cov khoom kom tsis txhob ncav cuag menyuam yaus thiab tsiaj.

Rov qab rau cov lus txheej txheem

Analogues ntawm cov tshuaj

Thaum muaj kev tawm tsam lossis kev tsis haum tshuaj, cov tshuaj tau raug pom zoo kom hloov nrog ib qho analog. Kev noj tshuaj ncua sijhawm los ntawm kev tsim cov tshuaj insulin rau tib neeg yog tsim nyog. Hloov cov tshuaj nrog nqaij npuas ntxiv ntawm cov tshuaj hormones yog tsis pom zoo. Ntawm cov tshuaj zoo sib xws, Insuman Bazal, Mikstard 30 NM, Rinsulin NPH thiab lwm yam tshuaj muaj ntshav qab zib muaj cov tshuaj insulin-isophan (INN) siv. Kev noj tshuaj thiab kev sib txuam yuav tsum yog tus kws kho mob tau sau thiab kuaj xyuas. Kev noj tshuaj rau tus kheej tsis tuaj yeem lees txais.

Thaum twg tsis tuaj yeem siv?

Muaj ob peb qhov kev tiv thaiv tsis zoo rau kev siv ntawm Humulin. Cov no suav nrog: hypoglycemia, uas tau tsau ua ntej noj tshuaj, thiab cov tib neeg rhiab rau cov khoom siv. Lub ntsiab tsis zoo yog hypoglycemia, uas tuaj yeem ua rau tsaus muag thiab txawm ua rau tuag, tab sis cov kev mob tshwm sim no tsis tshua muaj tshwm sim.

Cov kev txhaum fab hnyav dua:

txog siav
txog siav
hypotension
nce hws
khaus tawv
cov mem tes ceev.

Qee zaum cov kev qhia ua xeb hauv zos tuaj yeem tshwm sim, xws li hyperemia, edema. Nyob rau hauv cov ntaub ntawv ntawm overdose, lub cev kev coj ua hauv qab no tshwm sim:

ntshav qab zib,
siab tawm hws
mob taub hau
kiv tob hau thiab mob taub hau
blanching ntawm daim tawv nqaij,
tsis muaj zog
xeev siab
tachycardia
tshee.

Yuav tsum tau soj ntsuam ntshav qab zib kom tsawg, ib yam li qee kis muaj cov tsos mob yuav hloov. Txhawm rau tshem tawm cov mob pathology me me, koj tuaj yeem coj me me ntawm qabzib. Tom ntej no, koj yuav tsum tau hloov kho kev noj haus thiab kev noj haus kom zoo, nrog rau kev ua si lub cev. Nrog tus neeg kawm ntawv ntawm cov ntshav qab zib nruab nrab, glucagon yog muab tshuaj txhaj rau qhov txhab thiab qhov ncauj ntawm cov carbohydrates ua. Daim ntawv foos hnyav tau pom tus mob tsis hnov qab, nrhav tsis tau, cuam tshuam ntawm cov leeg hlwb.

Yuav siv li cas?

Cov tshuaj Humulin yuav tsum tau xaiv tus kheej nruj me ntsis. Cov tshuaj tsis tuaj yeem muab tshuaj hla dej. Qhov feem ntau txoj kev ntawm txoj kev lis ntshav yog nyob rau hauv daim tawv nqaij, qee zaum intramuscularly. Rau kev tswj hwm subcutaneous, thaj chaw ntawm lub duav, pob tw, xub pwg, thiab lub plab yog qhov tsim nyog. Hauv ib hlis, hauv ib qho chaw koj tsis tuaj yeem ua ntau dua 1 qhov kev txhaj tshuaj. Txij li qee cov txuj ci tsim nyog rau kev txhaj tshuaj subcutaneous ntawm cov tshuaj, nws yog qhov zoo dua los tso qhov txheej txheem no rau cov neeg kho mob thaum xub thawj. Thaum muab tshuaj rau, nws yog ib qho tseem ceeb kom tsis txhob nkag mus rau txoj leeg thiab tsis txhob txhuam qhov chaw txhaj tshuaj.

Ua ntej siv, daim cartridges thiab lub raj mis yuav tsum tau muab dov 10 zaug hauv xib teg ntawm koj txhais tes thiab muab ua kom tawg kom qhov kev tshem tawm no yog matte lossis xim ze rau mis. Nws yog tsis yooj yim sua kom co cov ntsiab lus ntawm lub vials meej, txij li cov ua npuas dej tawm los yuav ua rau nws nyuaj rau kev txiav txim siab qhov ntau npaum. Thaum npaj cov tshuaj insulin rau kev txhaj tshuaj, koj yuav tsum ua tib zoo ntsuas cov ncauj lus ntawm ampoule. Yog tias lumps, ib qho dej nag dawb, cov qauv ntawm phab ntsa zoo li frosty yog pom nyob hauv nws, cov tshuaj no tsis tuaj yeem siv.

Rau kev txhaj tshuaj, nws yog ib qho tsim nyog yuav tsum noj cov koob txhaj tshuaj ntawm lub ntim uas sib haum rau cov tshuaj yuav tsum tau. Tom qab cov txheej txheem, nws raug nquahu kom rhuav tshem rab koob thiab kaw qhov kov siv lub hau. Qhov no yog qhov tsim nyog txhawm rau kom tswj tau qhov tsis haum tshuaj, kom tiv thaiv tsis tau cov khoom ntawm cov khoom txawv teb chaws thiab huab cua mus rau hauv lub vial. Tsis txhob siv rab koob los yog koob txhaj tshuaj dua zaum ob. Khaws cov tshuaj no rau hauv qhov chaw txias tsaus. Tom qab pib siv, lub raj mis yuav khaws cia tsis pub ntev tshaj ib hlis.

Nrog rau kev qhia ntawm Humulin NPH, qee cov yam ntxwv ntawm nws txoj kev siv yuav tsum raug xam tias:

Txog kev kho mob pob qij txha, peb cov neeg nyeem tau siv DiabeNot siv tau zoo. Pom qhov nrov ntawm cov khoom no, peb tau txiav txim siab muab nws rau koj kom txaus siab.

dependence on insulin hauv tus neeg mob txo qis yog lub raum, adrenal, pituitary, lub qog, mob siab, kev ua haujlwm
hauv kev ntxhov siab, tus neeg mob xav tau cov tshuaj insulin ntxiv,
kev hloov tshuaj yog tsim nyog thaum hloov kev noj zaub mov noj lossis ua si qoj ib ce,
kev fab tshuaj uas tshwm sim hauv tus neeg mob tsis tuaj yeem cuam tshuam nrog kev siv tshuaj insulin,
qee zaum kev qhia ntawm cov tshuaj yuav xav tau kev kho mob ceev ceev.

Vim tias muaj kev pheej hmoo ntawm kev txhim kho hypoglycemia tom qab txhaj tshuaj, ib qho yuav tsum tsis kam tsav tsheb thiab tsav lub tshuab ua haujlwm.

Kev ua haujlwm ntawm cov tshuaj tsawg dua yog tias koj noj qhov ncauj tawm tsam, cov thyroid cov tshuaj hormones, tshuaj tua kab mob, tshuaj tua kab mob, glucocorticoids nyob rau hauv mus tib seem. Cov nyhuv ntawm cov tshuaj yog kho kom zoo dua yog tias koj haus ib txhij nrog nws:

ethanol
cov tshuaj hypoglycemic,
salicylates,
beta adenoblockers,
sulfonamides,
MAO inhibitors.

Clonidine thiab reserpine tuaj yeem ua rau cov tsos mob ntawm tus mob ntshav qab zib tsawg.

Kev ntsuas thiab tus nqi

Tus nqi nruab nrab ntawm ib pob ntawm Humulin NPH sib txawv ntawm 1000 rubles. Thaum tsis muaj cov tshuaj hauv cov khw muag tshuaj, koj tuaj yeem siv ib qho ntawm nws cov analogues. Nov yog:

Insulin-Ferein xwm ceev. Nyob rau hauv nws cov muaj pes tsawg leeg muaj ib nrab hluavtaws tib neeg cov insulin.Cov tshuaj muaj nyob rau hauv daim ntawv ntawm kev daws rau kev txhaj tshuaj subcutaneous.
Monotard NM. Cov tshuaj yog rau cov pab pawg ntawm cov tshuaj insulin nrog lub sijhawm ua haujlwm ntev, muaj nyob rau hauv daim ntawv ntawm kev ncua ntawm 10 ml hauv lub raj mis.
Humodar B. Muaj tib neeg cov tshuaj insulin, kuj tseem muaj nyob hauv 100 IU hauv 1 ml.
Pensulin SS yog lwm txoj hauv kev tiv thaiv ntawm lub sijhawm nruab nrab.

Ntawm qhov hloov pauv rau Humulin NPH muaj:

Humulin M3. Qhov no yog ob-ncua kev ncua uas muaj soluble tib neeg cov kua dej thiab ib qho kev ncua ntawm isofan insulin hauv ib qho ntawm 30:70, feem. Cov tshuaj yog ntsuas raws li cov tshuaj ntawm nruab nrab lub sijhawm, nws pib ua yeeb yam li ib nrab teev tom qab kev coj ua, tag nrho cov sijhawm ntawm cov nyhuv yog txog li 15 teev. Cov tshuaj yog muab tshuaj intramuscularly lossis subcutaneously. Txwv tsis pub, qhov ntsuas thiab contraindications kiag li zoo tshaj plaws nrog Humulin NPH, noj ob yam tshuaj no tuaj yeem ua ke nrog kev txhaj tshuaj.
Humulin Tsis tu ncua. Zoo li Humulin NPH, nws muaj cov tshuaj insulin DNA-based insulin. Txawm li cas los xij, cov tshuaj no hais txog kev siv tshuaj insulin sai sai, yog li ntawd, nws tuaj yeem ua ke nrog Humulin NPH.
Vozulim N. Muaj cov tib neeg insulin-isophan thiab hais txog cov tshuaj ntawm cov tshuaj nruab nrab. Nws yog siv nrog kev ceev faj rau cov neeg mob uas muaj mob hlwb hauv lub hlwb. Tus so ntawm cov lus pom zoo rau kev siv coincide nrog cov tshuaj qub.
Gensulin M. Muaj cov ua ke ntawm nruab nrab thiab luv luv insulins. Cov tshuaj yog muab tshuaj subcutaneously thiab pib ua hauv ib nrab ib teev.

Cov chaw muag tshuaj niaj hnub npaj los muab ntau txoj kev xaiv hauv insulin npaj rau cov ntshav qab zib. Txawm li cas los xij, vim muaj qhov sib txawv hauv cov muaj pes tsawg leeg thiab sijhawm ntawm kev nqis tes, tsuas yog tus kws tshaj lij tsim nyog yuav tsum xaiv cov analogue ntawm cov tshuaj muab tshuaj, txiav txim qhov ntau npaum li cas.

Kev Ntsuam Xyuas Rau Neeg Mob

Ntau tus neeg mob teb tau zoo rau ntau yam tshuaj insulin. Hauv tshwj xeeb, Humulin NPH tsis ua rau muaj kev tsis zoo, txawm hais tias cov lus qhia rau kev siv ceeb toom txog lawv. Cov tshuaj insulin los ntawm cov tshuaj yog zoo nqus yog tias cov tshuaj kom raug yog suav thiab kev txhaj tshuaj yog ua kom raug. Qhov tsuas yog pab txhawb rau qhov tsis zoo tshwm sim tuaj yeem yog qhov tsis tau teem caij tsis noj tshuaj los ntawm tus kws kho mob lossis kev txhaj tshuaj tsis raug los ntawm tus kws kho mob lossis tus neeg mob nws tus kheej. Txhawm rau zam qhov no, koj yuav tsum ua tib zoo ua txoj kev coj los tswj cov tshuaj. Tib txoj kev kom tsis txhob noj tshuaj ntau dhau thiab muaj phiv.

Humulin NPH yog kev npaj insulin los ntawm cov pab pawg ntawm cov tshuaj ntawm lub caij nyoog nruab nrab. Tsuas yog tus kws kho mob uas kho cov neeg mob ntshav qab zib yuav tsum tau muab tshuaj kho. Qhov kev ntsuas no yuav pab kom tsis txhob noj ntau dhau, qhov xaiv tsis raug ntawm cov tshuaj analogue thiab kev suav ntawm qhov ntim uas xav tau los ntawm tus neeg mob. Tus kws kho mob tseem tuaj yeem coj mus rau hauv cov xwm txheej tshwj xeeb rau kev siv thiab contraindications hauv tus neeg mob, uas yuav zam kev tsis zoo rau cov tshuaj.