Daim ntawv txiav txim - tsiav tshuaj: gelatinous khoom nrog lub cev pob tshab ntawm ob hom: loj No. 2 - nrog lub hau xim av, qhov loj me No. 0 - tsaus txiv kab ntxwv, sab hauv cov tshuaj ntsiav - enteric-coated pellets ntawm kheej kheej, kheej kheej lossis tsis zoo nkauj los ntawm xim av mus rau lub teeb xim av xim nrog qhov tshwj xeeb tsis hnov tsw (10 pcs. hauv blisters, hauv duab los qhia ntawm 2 lossis 5 ntim).

Cov tshuaj nquag ntawm Mikrasim yog pancreatin, hauv 1 tshuaj ntsiav:

Loj Me Zauv 2 - 10,000 IU (125 mg), uas yog sib npaug rau nominal lipolytic kev ua haujlwm ntawm 168 mg lossis kev ua haujlwm: amylase 7500 IU, lipase 10 000 IU, protease 520 IU,
Qhov loj me No. 0 - 25,000 units (312 mg), uas yog sib npaug rau nominal lipolytic kev ua haujlwm ntawm 420 mg lossis kev ua haujlwm: amylases 19,000 units, lipases 25,000 units, tiv thaiv 1,300 units.

Ntu cov khoom siv: enteric-soluble pellet plhaub - lub tshuab copolymer ntawm ethyl acrylate thiab methacrylic acid (1: 1) (nyob rau hauv 30% dispersion, ntxiv nrog muaj sodium lauryl sulfate thiab polysorbate 80), triethyl citrate, simethicone emulsion 30% (qhuav 32.6%) hauv qhov muaj pes tsawg leeg uas: methyl cellulose, ncua colloidal silicon, sorbic acid, precipitated silicon colloidal, talc, dej.

Cov sib xyaw ua ke ntawm cov tshuaj ntsiav lub cev: gelatin, dej.

Cov sib xyaw ua ke ntawm cov hmoov npog: gelatin, crimson zas (Ponceau 4R), xim xaim xim xiav, quinoline zas xim daj, titanium dioxide, dej.

Kev ntsuas rau siv

Pancreatic enzyme deficiency: pancreatic fibrosis (cystic fibrosis), mob qog nqaij hlav hlav, mob txha caj hlav, txhaws ntev, lub sijhawm tom qab phais mob ntawm tus txiav - raws li kev hloov kho,
Kev kho mob ntsig txog yog ib feem ntawm txoj kev kho mob nyuaj rau kev txhim kho ntawm lub plab zom mov uas tau tshwm sim los ntawm cov keeb kwm yav dhau los: ib qho mob tom qab rov ua haujlwm ntawm lub plab, lub plab, ib feem ntawm cov hnyuv, pathologies ntawm cov hnyuv me thiab loj, thiab duodenum, ua rau muaj kev cuam tshuam tsis zoo ntawm cov ntsiab lus hauv plab hnyuv, mob thiab kab mob nrog rau cov txheej txheem cuam tshuam. tshem tawm cov kua tsib, nrog rau tus mob cholecystitis, mob siab, lub pob zeb nyob hauv lub zais plab, cov kab mob mus ntev ua haujlwm ntawm cov hlab plab, nias ntawm lub bile boiling huam hlwv thiab hlav growths,
Kev txhim kho txoj kev zom zaub mov hauv cov neeg laus thiab cov menyuam yaus muaj lub luag haujlwm ntawm lub plab zom mov (GIT): nrog cov kev tsis zoo ntawm cov khoom noj (suav nrog kev noj zaub mov, noj ntxhib thiab rog, tsis noj zaub mov tsis haum), nrog rau lub neej ua kom tsis haum, ua tsis taus pa, lub neej ua haujlwm ntev,
Siv hauv kev npaj ua nyuaj rau kev kuaj mob ultrasound thiab xoo hluav taws xob ntawm lub plab plab hnyuv siab raum.

Cov Yuav Tsum Muaj

Mob ncauj mob taub hau
Mob caj dab ntev hauv tus mob huam,
Hypersensitivity rau cov tshuaj.

Lub sij hawm teem tseg ntawm Mikrazim thaum cev xeeb tub thiab kev pub niam mis yog qhia tau yog tias xav tias yuav kho tau zoo tshaj rau leej niam tshaj qhov ua tau pheej hmoo ua rau muaj menyuam hauv plab thiab menyuam yaus.

Tsuas tshuaj thiab tswj hwm

Cov tshuaj ntsiav tau noj ntawm qhov ncauj, muab ntxuav nrog qhov me me ntawm cov kua dej lossis kua txiv (nrog rau qhov tshwj xeeb ntawm cov kua alkaline). Thaum sau daim ntawv noj ib zaug ntawm 2 lossis ntau dua tshuaj ntsiav, nws raug nquahu kom noj ½ ntawm tag nrho cov tshuaj ua ntej noj mov, ib nrab ntxiv - ncaj qha thaum noj mov. Ib koob tshuaj 1 lub tshuaj ntsiav yog noj nrog zaub mov.

Rau cov menyuam yaus lossis cov neeg laus laus, txhawm rau txhawm rau nqos, koj tuaj yeem noj tshuaj tsis muaj lub plhaub tshuaj, yaj nws cov ntsiab lus rau hauv cov kua lossis kua zaub (pH hauv qab 5.0), uas tsis tas yuav zom (yogurt, txiv applesauce). Ntxo, zom pellets lossis sib xyaw nrog zaub mov (pH saum 5.5) rhuav tshem lawv daim nyias nyias, uas tiv thaiv kom tsis txhob mob kua zaub. Nws yog qhov tsim nyog los npaj cov hmoov sib tov nrog pellets nrog kua los yog khoom noj ua ntej tswj hwm ncaj qha.

Ib tug neeg xaiv cov koob tshuaj Mikrasim raug pom zoo kom coj mus rau hauv tus lej ntawm kev noj haus, qhov mob hnyav ntawm cov tsos mob ntawm tus kabmob thiab hnub nyoog ntawm tus neeg mob.

Siv cov tshuaj tuaj yeem kav ntev ntau hnub nrog kev mob plab zom mov mus rau ntau lub hlis thiab xyoo nrog kev hloov kho ntev.

Qhov siab tshaj plaws uas tau tso cai tau siv txhua hnub rau cov menyuam yaus: txog li ib thiab ib nrab xyoo - 50,000 units, thaum muaj hnub nyoog ib thiab ib nrab xyoo thiab laus dua - 100,000 units.

Pom zoo ntau npaum rau kev hloov kho ntau yam ntawm exocrine pancreatic tsis txaus:

Steatorrhea, nrog rau cov rog cov rog hauv cov quav ntau dua 15 g hauv ib hnub: 25,000 units ntawm lipase nrog txhua pluas noj rau cov neeg mob raws plab, poob phaus thiab tsis muaj txiaj ntsig los ntawm kev noj zaub mov zoo. Nrog kev tiv thaiv zoo ntawm cov tshuaj kom ua tiav cov txiaj ntsig kev soj ntsuam, qhov nce ntxiv ntawm ib koob rau 30,000-35,000 units ntawm lipase yog qhia. Thaum tsis muaj kev txhim kho hauv cov txiaj ntsig kho, nws yog ib qho tsim nyog kom paub meej txog kev kuaj mob lossis txo cov roj tsawg thiab xav txog lub sijhawm teem rau kev tswj hwm ntawm cov khoom siv tiv thaiv proton twj tso kua mis. Hauv kev tsis muaj mob raws plab thiab qhov hnyav ntawm lub keeb kwm yav dhau los ntawm me me steatorrhea, Mikrasim yog kho nyob rau hauv ib zaug ntawm 10,000-25,000 units ntawm lipase,
Cystic fibrosis: thawj zaug tshuaj rau cov menyuam yaus hnub nyoog qis dua 4 xyoos - raws li 1000 tauj ib lipase rau 1 kg ntawm tus menyuam qhov hnyav thiab 500 units lipase rau 1 kg - thaum muaj hnub nyoog 4 xyoos lossis ntau dua. Cov koob tshuaj yuav tsum tau muab coj los xav txog kev noj haus cov zaub mov zoo thiab mob hnyav ntawm steatorrhea. Kev teem sij hawm ntawm kev saib xyuas txij nkawm ntau dua 10,000 units ntawm lipase rau 1 kg ntawm lub cev qhov hnyav hauv ib hnub tsis raug pom zoo.

Cov lus qhia tshwj xeeb

Kev siv lub sij hawm ntev ntawm Mikrasim hauv kev txhaj tshuaj siab yuav tsum nrog cov kev saib xyuas mob niaj zaus.

Kev tsis muaj txiaj ntsig ntawm txoj kev kho tuaj yeem tiv thaiv keeb kwm yav dhau los ntawm kev tsis muaj zog ntawm cov enzymes los ntawm acidification ntawm cov ntsiab lus ntawm duodenum, concomitant kab mob ntawm txoj hnyuv me me (suav nrog dysbiosis thiab qhov mob tsis txaus), tsis ua raws li cov kev cai pom zoo, thiab kev tswj hwm ntawm cov enzymes uas tau ploj lawm.

Qhov tshwm sim ntawm pancreatin ntawm kev ceev ntawm tus neeg mob lub hlwb kev xav, nrog rau lub peev xwm tsav tsheb thiab cov txheej txheem, tseem tsis tau tsim.

Dosage daim ntawv

Cov tshuaj txig 10,000 units thiab 25,000 units

10000 DAIM PHI

25000 units

Ib qho tshuaj ntsiav muaj

cov tshuaj heev - pancreatin nyob rau hauv daim ntawv ntawm enteric pellets,

muaj cov hmoov ua rau pancreatin, uas tau ua rau cov haujlwm:

* - nyob rau hauv cov nqe lus ntawm nominal lipolytic kev ua.

pellet plhaub: methacrylic acid thiab ethyl acrylate copolymer 1: 1 (nyob rau hauv daim ntawv ntawm 30% dispersion, ntxiv rau muaj polysorbate-80, sodium lauryl sulfate) - 25.3 mg / 63.2 mg, triethyl citrate - 5.1 mg / 12.6 mg, simethicone emulsion 30% (qhuav hnyav, suav nrog suav nrog: dimethicone, precipitated silicon colloidal, ncua colloidal silicon, methyl cellulose, sorbic acid, dej) - 0.1 mg / 0.3 mg, talc - 12.6 mg / 31.6 mg,

rau qhov ntau npaum ntawm 10,000 units: cov hlau oxide daj E172 - 0.2240%, hlau oxide dub E172 - 0.3503%, hlau oxide liab E172 - 0.8077%, titanium dioxide E171 - 0.6699%, gelatin - txog li 100%,

rau qhov muab ntau npaum 25,000 units: ntxim nyiam liab E129 - 0.1400%, daj hlau oxide E172 - 0.3000%, titanium dioxide E171 - 0.5000%, gelatin - txog li 100%.

Cov tawv tawv gelatin tsiav tshuaj naj npawb 2 nrog rau cov ntaub ntawv pob tshab thiab lub hau ntawm cov xim av (rau ntau npaum li ntawm 10,000 units) lossis qhov loj me No. 0, nrog rau cov ntaub ntawv pob tshab thiab lub hau xim tsaus xim txiv kab ntxwv (rau qhov ntau npaum li 25,000 units).

Cov ntsiab lus ntawm cov tshuaj ntsiav yog pellets ntawm lub cylindrical lossis spherical lossis duab tsis xws luag los ntawm lub teeb xim av mus rau xim av xim, nrog tus yam ntxwv tsw.

Cov chaw muag tshuaj

Cov Tshuaj Pharmacokinetics

Pancreatin yog cov tshuaj cais tawm ntawm cov txiav ntawm tus tsiaj.

MICRASIM® muaj cov tshuaj tua kab mob pancreatin. Cov tshuaj muaj feem ntau siab molecular phaus enzyme proteins, ib qho me me ntawm cov zaub mov. Hauv cov kev tshawb fawb tsiaj, ib qho tsis muaj qhov nqus ntawm tag nrho (tsis cais) cov enzymes tau pom tias, thiab vim li ntawd, kev tshawb fawb pharmacokinetic classical tsis tau ua. Txij li thaum kho kev ua si ntawm kev npaj muaj pancreatic enzymes pom tau hais hauv lub lumen ntawm txoj hnyuv, qhov kev nqus tsis tau rau qhov tshwm sim ntawm lawv cov teebmeem. Ntxiv mus, nyob rau hauv lawv cov qauv tshuaj, enzymes yog cov protein thiab, yog li ntawd, thaum dhau los ntawm kev zom zaub mov, lawv raug tiv thaiv proteolytic cleavage kom txog thaum lawv tau nkag mus rau hauv daim ntawv ntawm peptides thiab amino acids.

Cov Tshuaj Hauv Tshuaj

Digestive enzyme khwv, lav rau qhov tsis muaj peev xwm ntawm pancreatic enzymes, muaj lipolytic, proteolytic, amylolytic effect.

Tom qab siv cov tshuaj, cov tshuaj ntsiav gelatin yaj ua rau lub plab hauv qab qhov kev ua ntawm lub plab zom mov, thiab cov kab mob pancreatin uas tawm tsam cov kua qaub yog yooj yim sib xyaw nrog cov ntsiab lus ntawm lub plab thiab, ua ke nrog cov zaub mov zom, nkag mus rau txoj hnyuv. Ntawm no, pellets poob lawv cov kua qaub-tiv taus daim nyias nyias, decompose thiab tso cov enzymes rau hauv plab hnyuv lumen, uas ua rau lub plab zom mov ntawm cov khoom noj ua ke.

Lipase txhawb kev rhuav tshem ntawm cov rog rau glycerol los ntawm hydrolyzing ether bonds ntawm txoj haujlwm 1 thiab 3 ntawm triglycerides ntawm cov roj ntsha.

Alpha-amylase hydrolyzes kua nplaum alpha-1,4-glycoside polymers. Nws tawg feem ntau ntawm cov tshuaj polysaccharides (hmoov txhuv nplej siab, glycogen thiab qee yam lwm yam carbohydrates) thiab kev xyaum tsis koom nrog cov hydrolysis ntawm tsob nroj fiber. Hmoov txhuv nplej siab thiab pectins lwj rau hauv cov suab thaj yooj yim - sucrose thiab maltose.

Cov Proteolytic enzymes - trypsin, chymotrypsin thiab elastase - zom cov protein rau cov amino acids. Ntxiv rau qhov no, trypsin, rhuav tshem cov cholecystokinin tso tawm yam, los ntawm cov ntsiab lus tawm tswv yim txwv tsis pub cov khoom noj uas ua rau lub cev tswj tsis taus pa, uas ua rau txo lub nra ntawm cov khoom no thiab yog li muab cov txiaj ntsig analgesic hauv kev mob ceev. Trypsin, sib cuam tshuam nrog RAP-2 receptors ntawm enterocytes, yog qhov tseem ceeb tshaj plaws tswj kev ua kom muaj zog ntawm txoj hnyuv me.

Cov tshuaj kho txhim kho lub xeev kev ua haujlwm ntawm txoj hnyuv plab, txoj kev zom plab zom mov.

Tsis zoo li cov ntsiav tshuaj pancreatin, microgranular daim ntawv ntawm pancreatin ua kom ntseeg tau sai ntawm cov tshuaj mus rau hauv duodenum los ntawm lub plab, qhov siab tshaj plaws enzymatic kev ua si ntawm cov tshuaj nyob rau hauv cov hnyuv me yog sau 30-45 feeb tom qab kev tswj hwm ntawm qhov ncauj.

Hauv seem qis ntawm txoj hnyuv me, cov kev ua ntawm pancreatin enzymes txo qis zuj zus, thaum lawv txav mus rau txoj hnyuv, lawv tsis ua haujlwm thiab muaj qee qhov kev ua haujlwm, cov seem ntawm cov tshuaj tau tawm ntawm txoj hnyuv nrog rau cov khoom zom.

Tsuas tshuaj thiab tswj hwm

Cov tshuaj ntawm cov tshuaj raug xaiv xaiv tus kheej. Cov koob tshuaj ntawm cov tshuaj (hais txog lipase) nyob ntawm lub hnub nyoog thiab degree ntawm enzyme deficiency. Kuj tseem coj mus rau hauv tus account txheeb ze cov ntsiab lus ntawm cov enzymes uas hydrolyze cov protein thiab carbohydrates, nyob ntawm cov khoom xyaw ntawm kev noj haus thiab cov kab mob ntsig txog.

Cov neeg laus noj cov tshuaj thaum noj mov. Capsules yog nqos tag nrho, tsis muaj tawg lossis zom, nrog dej ntau. Tsis txhob siv dej alkaline ntxhia dej ntxhua khaub ncaws. Yog tias ib qho koob tshuaj ntau dua ib qho tshuaj ntsiav, koj yuav tsum siv li ib nrab lossis ib feem peb ntawm cov tshuaj pom zoo ua ntej noj mov, qhov seem nrog cov zaub mov noj.

Txhawm rau siv tshuaj, cov neeg laus uas muaj teeb meem nqos thiab cov menyuam yuav tsum qhib lub tshuaj ntsiav thiab ntxiv pellets rau cov khoom noj uas tsis tas yuav zom (khoom noj khoom qab zib, txiv applesauce, yogurt, thiab lwm yam). Npaj npaj yuav tsum noj tam sim ntawd. Kev sib tsoo lossis zom ntxau ua rau muaj kev ua txhaum ntawm lawv cov kua qaub-tiv thaiv daim nyias nyias, tso tawm pancreatic enzymes sai sai ploj kev ua thiab, ntxiv rau, tuaj yeem ua rau daim tawv nqaij xoos ntawm lub qhov ncauj thiab txoj hlab pas.

Cystic fibrosis. Thawj qhov tshuaj xyuas tau rau cov menyuam yaus hnub nyoog qis dua 4 xyoos yog 1000 PIECES ntawm lipase ib kilogram ntawm lub cev qhov hnyav ntawm txhua qhov kev pub noj, rau cov menyuam muaj hnub nyoog tshaj 4 xyoos - 500 PIECES ntawm lipase ib phaus ntawm ib pluas noj. Cov koob tshuaj yuav tsum tau xaiv ib tus zuj zus, nyob ntawm qhov mob hnyav, qhov mob hnyav ntawm steatorrhea thiab kev noj zaub mov zoo. Kev saib xyuas cov tshuaj rau cov neeg mob feem ntau yuav tsum tsis pub ntau tshaj 10,000 units ntawm lipase ib phaus ntawm lub cev hnyav ib hnub.

Qhov koob tshuaj txhua hnub tuaj yeem faib ua ntau zaug ntawm ncua sijhawm 1-2 teev.

Txij li nws nyuaj rau faib cov ntsiab lus ntawm cov tshuaj ntsiav rau hauv ntau qhov tshuaj, nws raug nquahu tias kev kho mob nrog MIKRAZIM® 10000 UNIT tau pib rau hauv cov menyuam yaus uas muaj lub cev qhov hnyav tsawg kawg 10 kg, thiab kev kho mob nrog MIKRAZIM® 25000 UNIT raug pom zoo kom pib hauv cov menyuam yaus uas muaj lub cev qhov hnyav tsawg kawg yog 25 kg.

Lwm yam ntawm exocrine pancreatic tsis txaus. Hauv kev hloov pauv hauv cov neeg mob uas muaj mob txhaws qog, kev noj tshuaj ntawm enzymes raug xaiv ib tus zuj zus raws li qhov tsis txaus ntawm exocrine, zoo ib yam li tus neeg mob noj zaub mov zoo.

Nrog cov ntsiab lus tseem ceeb (ntau dua 15 grams tauj ib hnub) cov rog nyob hauv cov quav, ntxiv rau muaj mob raws plab thiab yuag poob, thaum kev noj zaub mov tsis muaj txiaj ntsig tseem ceeb, 25,000 units ntawm lipase tau sau tseg (cov ntsiab lus ntawm ib qho tshuaj ntsiav ntawm MICRASIM® 25,000 units) nrog txhua pluas noj. Yog tias tsim nyog, thiab nrog kev tiv thaiv zoo ntawm cov tshuaj, ib koob tshuaj ntxiv tau nce mus txog 30,000 - 35,000 (peb tsiav tshuaj ntawm MICRAZIM® 10000 UNIT lossis ib qho tshuaj ntsiav ntawm MICRAZIM® 10000 UNIT thiab MICRAZIM® 25000 UNIT, feem).

Ib qho kev nce ntxiv ntawm koob tshuaj, feem ntau, tsis txhim kho cov txiaj ntsig ntawm kev kho mob thiab yuav tsum tau rov qab tshuaj ntsuam xyuas, qhov kev cuam tshuam ntawm cov rog hauv cov zaub mov noj.

Mikrazim ntsiav tshuaj: yuav ua li cas coj cov neeg laus nrog mob pancreatitis?

Micrazim (lub npe thoob ntiaj teb tsis yog lub npe yog broad-spectrum digestive enzyme) yog cov tshuaj sib txuas ua ke uas suav nrog ntau yam ntawm cov enzymes uas tawm tsam tawm tsam tag nrho cov as-ham. Siv rau normalize plab zom mov thiab txhim kho cov kev ua ntawm kev zom zaub mov.

Vim tias qhov tseeb hais tias lub ntsiab ntawm cov enzymes digestive tshwm sim hauv cov hlwb ntawm tus txiav, lawv cov synthesis thiab excretion yuav cuam tshuam vim cov txheej txheem pathological.

Hauv cov xwm txheej zoo li no, lo lus nug yog hais txog kev teem caij kho qee yam kev kho mob. Nws yog rau cov hom phiaj ntawd tias kev kho enzyme yog tus kws kho.
Qhov tshuaj yeeb tshuaj no muaj nyob rau hauv daim ntawv ntawm microspheres ntim hauv nkaws tsiav tshuaj. Cov tshuaj ntsiav, nyeg, raws li tus txheej txheem thoob ntiaj teb rau kev khaws thiab faib tshuaj, tau ntim rau hauv cov hlwv tshwj xeeb hauv hlau. Nws yog cov ntim no uas muab kev tiv thaiv ua tiav ntawm cov tsiav tshuaj los ntawm qhov kev puas tsuaj ntawm ib puag ncig. Cov hlwv tau tso rau hauv ib lub thawv ntawv cardboard. Ib lub thawv twg muaj qee qhov hlwv. Ib qho ntxiv, txhua pob muaj cov lus qhia.

Cov tshuaj nquag siv ntawm cov tshuaj yog classic pancreatin. Nws yog nthuav tawm nyob rau hauv daim ntawv ntawm hmoov, ib qho kev tawm ntawm npua pancreatic enzymes. Cov khoom yog sawv cev los ntawm cov enzymes hauv qab no:

lipase, ib qho enzyme tshwj xeeb ua lub luag haujlwm tawg rau lipid Cheebtsam,
amylase, ib qho enzyme uas txhawb nqa lub zom plab kom nquag plias ntawm polysaccharides,
trypsin, lub luag haujlwm rau qhov tawg ntawm cov protein.

Hauv kev lag luam tshuaj hauv tsev, cov tshuaj tau hais tawm hauv ob daim ntawv:

Dosage ntawm 10 txhiab units ntawm kev txiav txim. Nrog cov ntsiab lus ntawm 125 milligrams ntawm cov tshuaj nquag.
Micrasim nrog nrog ntau npaum ntawm 25000 muaj 312 milligrams ntawm pancreatin hmoov.

Cov tshuaj yog tsim los ntawm cov kws lag luam tshuaj muaj txiaj ntsig - “ABBA-RUS”. Lub npe ntawm cov tshuaj muaj feem xyuam nrog daim ntawv tso tawm ntawm microsphere, thiab cov tshuaj nquag yog enzyme.

Hauv kev tsim cov khoom siv ntau enzymes siv cov khoom siv raw ntawm cov tsiaj keeb kwm - ib qho enzyme extract ntawm lub txiav ntawm cov tsiaj txhu ua liaj ua teb, uas yog npua.