Glidiab pauv hloov: cov nqi rau cov tshuaj analogues thiab cov khoom ntawm cov tshuaj
Ib qho tshuaj hypoglycemic qhov ncauj los ntawm cov pab pawg ntawm sulfonylurea derivatives, uas txawv ntawm cov tshuaj zoo sib xws los ntawm qhov muaj cov N-muaj heterocyclic nplhaib nrog kev ua kom cov kabmob endocyclic.
Gliclazide txo qis kom cov ntsiab lus zoo ntawm cov piam thaj hauv cov ntshav, txhawb lub zais ntshav ntawm insulin los ntawm β-hlwb ntawm islets ntawm Langerhans. Ib qho nce ntxiv ntawm cov qib ntawm cov tshuaj tua kab mob postprandial thiab C-peptide mob tsawv tom qab 2 xyoos dhau los ntawm kev kho. Ntxiv nrog rau cov nyhuv ntawm cov metabolism hauv cov metabolism, gliclazide muaj cov teebmeem hemovascular.
Ntxim rau insulin secretion
Hauv hom 2 mob ntshav qab zib mellitus, cov tshuaj rov qab ua rau lub sijhawm thaum kawg ntawm cov kua dej hauv cov kua dej hauv cov lus teb rau cov piam thaj thiab ua rau qib thib ob ntawm insulin zais cia. Ib qho tseem ceeb nce ntxiv ntawm insulin secretion tau pom nyob rau hauv teb rau kev tsa ua vim kev noj zaub mov thiab qabzib kev tswj hwm.
Glyclazide txo txoj kev pheej hmoo ntawm cov ntshav me me kom tsis muaj teeb meem, muaj feem xyuam rau cov txheej txheem uas tuaj yeem ua rau muaj kev txhim kho ntawm kev mob ntshav qab zib mellitus: ib feem ntawm kev ua kom tsis muaj platelet sib xyaw thiab kev ua rau lub ntsej muag thiab txo qis ntawm kev ua kom cov platelet ua haujlwm (beta-thromboglobulin, thromboxane B2), nrog rau kev rov qab ua haujlwm ntawm fibrinolytic vascular nce kev ua si ntawm cov nqaij mos plasminogen activator.
Kev tswj hwm glycemic ntau ntxiv raws li kev siv tshuaj Diabeton® MB (glycosylated hemoglobin (HbA1c) 65 xyoos) - 30 mg (1/2 ntsiav tshuaj) ib hnub.
Thaum muaj kev tswjhwm txaus, cov tshuaj hauv qhov tshuaj no tuaj yeem siv rau kev kho kho. Nrog kev tswj tsis tau glycemic txaus, koob tshuaj txhua hnub tuaj yeem raug nce mus rau 60 mg, 90 mg lossis 120 mg. Qhov koob tshuaj nce siab yog ua tau tsis tau ntxov dua tom qab 1 lub hlis ntawm kev siv tshuaj kho nyob rau ntawm lub koob tshuaj uas tau qhia dhau los. Qhov tshwj tsis yog cov neeg mob uas cov ntshav qabzib concentration tsis tau txo tom qab 2 lub lis piam ntawm kev kho. Nyob rau hauv cov xwm txheej zoo li no, cov koob tshuaj yuav raug nce 2 lub lis piam tom qab pib ua haujlwm.
Qhov siab tshaj plaws uas pom zoo hauv kev siv tshuaj txhua hnub yog 120 mg.
1 ntsiav tshuaj nrog qhov hloov kho tawm (MB) 60 mg yog sib npaug rau 2 ntsiav tshuaj nrog qhov hloov pauv 30 mg Lub xub ntiag ntawm qhov kev tshaj tawm ntawm 60 mg ntsiav tshuaj tso cai rau koj faib cov ntsiav tshuaj thiab noj ib koob tshuaj 30 mg (1/2 ntsiav tshuaj 60 mg), thiab yog tias tsim nyog 90 mg (1 ntsiav tshuaj 60 mg thiab 1/2 ntsiav tshuaj 60 mg).
Txoj kev hloov los ntawm kev noj tshuaj Diabeton ® ntsiav tshuaj 80 mg rau cov tshuaj Diabeton® MB ntsiav tshuaj nrog kev hloov pauv ntawm 60 mg:
1 lub tshuaj ntawm cov tshuaj Diabeton® 80 mg tuaj yeem hloov los ntawm 1/2 ntsiav tshuaj nrog qhov hloov pauv hloov Diabeton® MB 60 mg. Thaum hloov cov neeg mob los ntawm Diabeton® 80 mg rau Diabeton® MB, kev ceev faj glycemic pom zoo.
Txoj kev hloov pauv ntawm kev noj lwm cov tshuaj hypoglycemic mus rau lub tshuaj Diabetoniabet MB ntsiav tshuaj nrog kev hloov pauv ntawm 60 mg:
Cov tshuaj Diabeton ® MB ntsiav tshuaj nrog kev hloov pauv ntawm 60 mg tuaj yeem siv hloov lwm tus hypoglycemic tus neeg sawv cev rau kev tswj hwm qhov ncauj. Thaum hloov mus rau cov neeg mob tau txais lwm cov tshuaj hypoglycemic rau kev tswj hwm qhov ncauj rau Diabeton® MB, lawv cov koob tshuaj thiab ib nrab ntawm lub neej yuav tsum raug txiav txim siab. Raws li txoj cai, lub sijhawm hloov pauv tsis tas yuav tsum muaj. Qhov muab tshuaj thawj zaug yuav tsum yog 30 mg thiab tom qab ntawv ua raws li lub siab ntawm cov ntshav qabzib.
Thaum Diabeton® MB hloov nrog sulfonylurea derivatives nrog lub neej ib nrab ntev kom tsis txhob mob ntshav qab zib vim tshwm sim los ntawm cov nyhuv ntxiv ntawm ob tus kab mob hypoglycemic, koj tuaj yeem nres noj lawv rau ob peb hnub. Thawj koob tshuaj ntawm cov tshuaj Diabeton® MB tseem yog 30 mg (1/2 ntsiav tshuaj 60 mg) thiab, yog tias tsim nyog, tuaj yeem nce ntxiv tau yav tom ntej, raws li tau piav qhia saum toj no.
Ua ke nrog lwm cov tshuaj hypoglycemic
Diabeton® MB tuaj yeem siv nrog kev sib xyaw nrog biguanidines, alpha glucosidase inhibitors lossis insulin.
Nrog kev tswj tsis tau glycemic tsis txaus, kev kho tshuaj insulin ntxiv yuav tsum tau txiav txim siab nrog kev saib xyuas mob siab.
Cov pab pawg neeg tshwj xeeb
Kev txhaj tshuaj rau cov neeg mob uas laus dua 65 xyoos tsis tas yuav tsum tau ua.
Cov kev tshawb fawb soj ntsuam tau pom tias koob hloov kho rau cov neeg mob uas mob mentsis txog rau lub raum tsis ua hauj lwm lawm. Pom zoo kev saib xyuas kev mob nkeeg.
Hauv cov neeg mob uas muaj kev pheej hmoo txhim kho hypoglycemia (noj tsis txaus los yog tsis noj zaub mov noj tsis txaus, mob hnyav lossis nyiaj tsis txaus los ntawm cov kab mob endocrine - pituitary thiab adrenal tsis txaus, hypothyroidism, tshem tawm corticosteroids tom qab siv sijhawm ntev thiab / lossis tau txhaj ntau dua, cov kab mob hnyav ntawm cov hlab plawv - kev mob ntshav siab ntawm cov hlab ntshav liab, mob heev ntawm cov mob carotid rau cov hlab ntsha, cov leeg mob atherosclerosis), nws raug nquahu kom siv cov koob tshuaj tsawg kawg (30 mg) ntawm cov tshuaj Diabeton® MB.
Yuav kom ua tiav kev tswj hwm glycemic kom tiv thaiv kev mob ntshav qab zib, koj tuaj yeem maj mam nce cov koob tshuaj Diabeton® MB txog 120 mg rau ib hnub ntxiv rau kev noj haus thiab kev tawm dag zog kom ua tiav cov hom phiaj ntawm HbA1c. Nco ntsoov cov kev pheej hmoo ntawm kev txhim kho hypoglycemia. Tsis tas li ntawd, lwm cov tshuaj hypoglycemic, piv txwv li, metformin, alpha-glucosidase inhibitor, thiazolidinedione derivative lossis insulin, tuaj yeem raug ntxiv rau kev kho mob.
Cov ntaub ntawv hais txog kev ua haujlwm zoo thiab muaj kev nyab xeeb rau cov tshuaj hauv cov menyuam yaus thiab cov hluas hnub nyoog qis dua 18 xyoo tsis muaj.
Cov lus qhia rau kev siv
Glyclazide (sulfonylurea derivative thiab ib yam khoom uas tau los ntawm sulfamide) yog lub ntsiab lus tseem ceeb ntawm cov tshuaj. Nws ua lub ntsej muag hypoglycemic (hypoglycemic).
Hauv qab ntawm qhov sib txuam ntawm cov khoom siv no, tsim tawm ntawm cov tshuaj insulin nyob rau hauv lub txiav thiab ua haujlwm ntawm ib qho tshwj xeeb glycogen synthetase enzyme tau qhib.
Gliclazide maximally compresses lub sijhawm thaj tsam ntawm kev noj mov thiab pib ntawm kev ua haujlwm nquag ntawm lub qab zib los tsim cov tshuaj insulin, txo cov postprandial glycemia (qib qab zib tom qab noj).
Tsis tas li ntawd, cov tshuaj txwv tsis pub cov nplaum ntawm cov ntshav (platelet sib sau ua ke), txo qhov rhiab heev ntawm cov hlab ntshav mus rau cov tshuaj hormone-adrenaline thiab muaj kev pheej hmoo ntawm atherosclerotic plaques rau ntawm cov hlab ntsha.
Cov tshuaj uas ntxiv cov tshuaj muaj xws li: lactose (mis nyuj muaj suab thaj), thickener (ntsev ntawm magnesium thiab stearic acid), tshuaj talc, cellulose, hmoov txhuv nplej siab.
Cov tshuaj yog kom tiav los ntawm cov hnyuv, cov tshuaj lom hauv cov ntshav yog pom tom qab 6 teev. Txoj kev tshem tawm yog ua los ntawm cov hnyuv thiab raum.
Kev taw qhia thiab contraindications
Glidiab txoj kev kho yog kho rau tus mob hyperglycemia ntawm yam thib ob (tsis mob ntshav qab zib-insulin-mob ntshav qab zib mellitus) nrog rau kev kho kev noj haus.
Contraindications los siv yog:
Cov tshuaj rau cov ntshav qab zib Forsig thiab nws cov analogues.
- Tus mob DKA (mob ntshav qab zib ketoacidosis),
- hyperglycemia (ntshav qab zib) ntawm thawj hom,
- lub sij hawm ntawm kev coj tus kheej thiab pub mis rau menyuam,
- mob tsis zoo rau lub raum thiab lub siab ua haujlwm,
- txo hauv cov qe ntshav dawb,
- ntshav sodium siab thiab qabzib (hyperosmolar coma),
- kem plab thiab hnyuv tav,
- ib tug neeg intolerance.
Cov tshuaj tsis yog kws kho rau cov menyuam yaus, cov neeg mob haus cawv ntau thiab mob qog ntev.
Tsuas tshuaj thiab muab ntau npaum
Glidiab yog tsim nyob rau hauv cov ntsiav tshuaj daim ntawv ntawm 80 mg ntawm yam muaj sia nyob hauv ib ntsiav tshuaj. Cov pob muaj 60 daim. Tseem muaj cov ntsiav tshuaj ntev ntawm Glidiab MV.
Cov koob tshuaj yog xam los ntawm tus kws kho mob ib leeg zuj zus rau txhua tus neeg mob, noj mus rau hauv tus account qhov hloov pauv ntawm cov piam thaj hauv cov ntshav ua ntej noj, thiab tom qab nws. Feem ntau, txoj kev kho yog pib nrog qhov nruab nrab ib hnub ntawm 80-160 mg (320 qhov siab tshaj plaws).
Kev noj tshuaj yog qhia ob zaug ib hnub. Yog tias nws yog qhov yuav tsum tau nce koob tshuaj, lub sijhawm sib txawv ntawm kev hloov pauv ntawm kev siv tshuaj yeeb yog tsawg kawg yog ob lub lis piam.
Nta
Kev kho mob nrog cov tshuaj yuav tsum tau soj ntsuam txhua hnub ntawm cov piam thaj, nrog rau kev ua raws li cov zaub mov qis carb. Yog tias muaj kev ua txhaum ntawm kev noj zaub mov noj, ntxiv dag zog rau lub cev, ua kom lub siab ntxhov siab, nws yuav tsum qhia tus kws kho mob txog qhov no kom hloov cov tshuaj ntawm cov tshuaj.
Thaum ua ke nrog haus cawv muaj cawv, txhua tus tsos mob ntawm intoxication loj yog pom (ntuav, kiv taub hau, mob taub hau thiab mob plab).
Kev txo qis hauv qhov ua tau zoo ntawm kev kho ua rau muaj kev sib txuam ntawm cov tshuaj diuretics thiab tshuaj tiv thaiv.
Manifestation of phiv:
- tawm hws ntau dhau (hyperhidrosis),
- kev tswj tsis tau qhov leeg mob (mob plab),
- lub plawv dhia qeeb (bradycardia),
- nce qab los noj mov
- distracted mloog
- kev nkees nkees, qaug zog, tsis quav ntsej,
- txhob lam npau taws,
- kev zom thiab mob plab zom mov nyuaj (dyspepsia),
- mob plab (raws plab),
- cov ua xua ntawm caj ces.
Kev noj tshuaj ntau dhau tsis tso cai! Kev mob hypoglycemic coma tuaj yeem yog los ntawm tsis saib xyuas cov lus qhia kho mob.
Cov tshuaj yog tsim nyob rau hauv Russia los ntawm Akrikhin OJSC. Tus nqi yog hais txog 135 rubles.
Glidiab muaj cov yeeb yaj kiab zoo ib yam los ntawm gliclazide, lawv raug xa mus ua cov tshuaj muaj tseeb. Cov tshuaj kho mob yog tsim los ntawm ntau lub tuam txhab ua lag luam nyob hauv Russia thiab txawv teb chaws, tus nqi nruab nrab ntawm kev ntim tsis tshaj 250 rubles.
Glidiab cov lus ua nyob rau hauv Lavxias Federation: Glyclazide, Glucostabil.
Tshuaj Muaj Nqis: Diabeton (Fabkis), Gliclad (Slovenia), Gluktam (Fabkis), Diabinaxi Diatika (Is Nrias teb), Glioral (Yugoslavia), Diabresid (Ltalis), Oziklid (Ireland).
Tsis tas li ntawd, muaj cov tshuaj muaj ntsis zoo ib yam li Glidiab hauv kev txiav txim siab hypoglycemic, lub tshuaj nquag ntawm uas yog glimepiride. Nws ua lub luag haujlwm zoo li gliclazide, yog qhia rau siv nyob rau hauv ntev hyperglycemia ntawm hom thib ob.
Cov txheej txheem rau kev hloov pauv zoo li no tsis txawv ntawm Glidiab. Cov kev mob tshwm sim txuas nrog kev siv ntau dhau, txwv tsis pub daim ntawv teev tsis muaj qhov tsis txaus siab raug txo qis (bradycardia, tsaug zog nrawm, dyspepsia, tawv nqaij ua xua). Kev Kho Mob yog nqa tawm nrog rau kev noj haus.
Cov tshuaj tiv thaiv kab mob German:
- Amaril. Lub tuam txhab: Aventis Pharma Deutschland GmbH. Nqi - 1280 r,
- Maninil. Ntau Lawm: Berlin-Chemie AG / Menarini Pab Pawg. 130 rubles.
- Glibenclamide. Cov Tshuaj Lag Luam Akrikhin HFK, ALSI Pharma, Antiviral, Bivitech, Biosynthesis. Tus nqi yog kwv yees li 200 rubles.
- Glimepiride. Nws yog tsim los ntawm Vertex, Pharmstandard-Leksredstva tuam txhab. Tus nqi yog -190 rubles.
Tseem muaj Czech counterparts Amiks thiab. Ntau Lawm Zentiva, ntawm tus nqi ntawm 670 rubles, thiab Greek version Glyurenorm. Chaw tsim tshuaj paus: BoehringerIngelheimEllas, ntawm tus nqi ntawm 450 p.
Hauv kev phais mob, nws yog ib qho tsim nyog yuav tsum qhia rau tus kws kho mob txog kev kho nrog Glidiab lossis nws cov analogues, txij li lub sijhawm teem cov tshuaj insulin tsis raug cais tawm.
Glidiab Hloov Kev Ntsuam Xyuas
Ntshav qab zib Hom 2 tsis yog kab lus. Kuv tau noj cov tshuaj Glidiab tau ntau xyoo, uas pab tswj hwm kuv cov ntshav qab zib.Cov. Ntawm kev muag khoom, tau kawg, muaj cov cuab yeej niaj hnub no ntau dua, tab sis lawv muaj ntau zaus ntau kim. Kuv cov tshuaj muaj nqi pheej yig thiab siv tau zoo.
Vim yog txoj kev kho tsis raug ntawm ib qho ntawm cov kab mob, qab zib pib sawv hauv kuv. Raws li qhov tshwm sim, kev kuaj mob yog hom 2 ntshav qab zib. Tus kws kho mob tau sau tseg rau Glutenorm. Kuv ua siab ncaj txais nws, thiab paub tias qhov ua tau zoo. Tab sis cov tshuaj muaj cawv yuav luag tsis tu ncua, tab sis nws raug nqi ntau. Ntawm kev tawm tswv yim, hloov nws nrog Glidiab. Qhov tshwm sim zoo li qub, tab sis tus nqi yog peb zaug tsawg dua.
Yawg tau muaj ntshav qab zib tau ntev heev. Nws yog tus kws kho mob ntshav qab zib, uas kuv ib txwm yuav. Txog lub sijhawm kawg, tsis muaj Diabeton hauv cov tsev muag tshuaj. Tus kws muag tshuaj qhia kom hloov Glidiab. Kuv nyuam qhuav yuav lub ntim khoom. Raws li kev tshuaj xyuas, cov tshuaj txo cov ntshav qab zib kom tsawg, hauv txhua txoj kev nws tsim nyog rau kev kho.
Glidiab analogs
Ib qho nyiaj tau los yog kim dua los ntawm 8 rubles.
Gliclazide MV yog ntsiav tshuaj npaj rau kev kho mob ntawm hom 2 mob ntshav qab zib mellitus raws li cov kev cuam tshuam tib yam hauv kev muab tshuaj ntawm 30 mg. Nws yog tsim rau kev noj haus tsis zoo thiab kev tawm dag zog. Gliclazide MV yog sib xyaw rau cov neeg mob ntshav qab zib hom 1 (insulin-dependant).
Ib qho nyiaj tau ntxiv yog kim dua los ntawm 10 rubles.
Akrikhin (Russia) Glidiab yog ib qho kev hloov pauv zoo tshaj plaws rau gliclazide. Nws kuj tseem muaj nyob hauv daim ntawv foos ntsiav tshuaj, tab sis qhov ntau npaum ntawm DV ntau dua ntawm no, uas yuav tsum tau coj mus rau hauv tus account ua ntej pib kev kho mob. Nws yog qhia rau tus mob ntshav qab zib hom 2 nrog kev noj zaub mov tsis zoo thiab kev siv lub cev.
Cov analogue kim dua los ntawm 168 rubles.
Lavxias ntsiav tshuaj npaj rau kev kho mob ntshav qab zib. Cov tshuaj nquag: gliclazide hauv ib qhov tshuaj ntawm 60 mg rau ib ntsiav tshuaj. Nws yog qhia rau kev kho mob ntshav qab zib hom 2 thiab rau cov hom phiaj prophylactic.
Cov analogue yog kim dua los ntawm 72 rubles.
Chaw tsim tshuaj paus: Tus Kws Tshuaj (Russia)
Cov Ntawv Tso Tawm:
- Tab. 2 mg, 30 pcs., Nqe txij li 191 rubles
- Tab. 3 mg, 30 pcs., Nqe txij li 272 rubles
Cov lus qhia rau kev siv
Glimepiride yog tshuaj siv hauv tsev rau kev kho mob ntshav qab zib hom 2. Muaj nyob hauv daim ntawv ntawm cov ntsiav tshuaj uas muaj tib lub tshuaj nquag hauv qhov ntau npaum ntawm 2 txog 4 mg rau ib ntsiav tshuaj.
Ib qho nyiaj tau los yog kim dua los ntawm 9 rubles.
Chaw tsim tshuaj paus: Yog tau meej
Cov Ntawv Tso Tawm:
- Tab. nrog MV 30 mg, 30 pcs., Nqe los ntawm 128 rubles
- Tab. 3 mg, 30 pcs., Nqe txij li 272 rubles
Cov lus qhia rau kev siv
Diabetalong yog ib ntsiav tshuaj tshuaj rau kev kho mob hom 2 mob ntshav qab zib mellitus raws li gliclazide hauv ib qhov nyiaj ntawm 30 mg. Cov tshuaj yog tshuaj nrog lub txiaj ntsig tsis txaus ntawm kev siv lub cev thiab kev noj haus. Muaj cov contraindications thiab cov kev mob tshwm sim.
Cov analogue yog pheej yig dua los ntawm 73 rubles.
Chaw tsim tshuaj paus: Valenta (Russia)
Cov Ntawv Tso Tawm:
- 5 mg ntsiav tshuaj, 50 pcs., Nqe txij li 46 rubles
- Tab. 3 mg, 30 pcs., Nqe txij li 272 rubles
Cov lus qhia rau kev siv
Glibenclamide yog cov tshuaj pheej yig dua hauv Lavxias rau kev kho mob ntshav qab zib nrog tib yam tshuaj sib xyaw ua ke. Qhov ntau npaum li cas yog nyob ntawm lub hnub nyoog ntawm tus neeg mob thiab qhov hnyav ntawm kev kho mob ntshav qab zib.
Ib qho hluav taws xob tsis kim dua los ntawm 190 rubles.
Chaw tsim tshuaj paus: Sanofi-Aventis S.p.A. (Ltalis)
Cov Ntawv Tso Tawm:
- Tab. 1 mg, 30 pcs., Nqe los ntawm 309 rubles
- Tab. 2 mg, 30 pcs., Nqe txij li 539 rubles
Cov lus qhia rau kev siv
Amaryl yog kev kho mob rau tus mob ntshav qab zib hom 2 hauv daim ntawv ntawm cov ntsiav tshuaj npaj rau kev siv sab hauv. Raws li cov tshuaj nquag, glimepiride siv nyob rau hauv qhov ntau npaum 1 txog 4 mg. Muaj cov contraindications thiab cov kev mob tshwm sim.
Ib qho hluav taws xob tsis kim dua los ntawm 20 rubles.
Chaw tsim tshuaj paus: Berlin-Chemie / Menarini Pharma (Lub Teb Chaws Yelemees)
Cov Ntawv Tso Tawm:
- 5 mg ntsiav tshuaj, 120 pcs., Nqe los ntawm 139 rubles
- Tab. 2 mg, 30 pcs., Nqe txij li 539 rubles
Cov lus qhia rau kev siv
Cov tshuaj ntsiav tshuaj rau kev kho mob ntshav qab zib mellitus raws li glibenclamide (hauv micronized daim ntawv) hauv qhov tshuaj ntawm 1,75 mg. Nws yog qhia siv nyob rau hauv hom 2 mob ntshav qab zib mellitus (nrog qhov tsis muaj txiaj ntsig ntawm kev noj haus tsis zoo).
Cov kab xev analogue kim dua los ntawm 67 rubles.
Chaw tsim tshuaj paus: Canonpharma (Russia)
Cov Ntawv Tso Tawm:
- Tab. 2 mg, 30 pcs., Nqe txij li 186 rubles
- Tab. 4 mg, 30 pcs., Nqe los ntawm 252 rubles
Cov lus qhia rau kev siv
Glimepiride Canon yog ib qho txiaj ntsig zoo rau kev kho mob ntawm hom 2 mob ntshav qab zib mellitus raws li glimepiride hauv kev siv tshuaj zoo ib yam. Nws yog tshuaj rau qhov tsis muaj txiaj ntsig ntawm kev noj haus thiab kev ua lub cev.
Cov analogue yog kim dua los ntawm 91 rubles.
Chaw tsim tshuaj paus: Akrikhin (Russia)
Cov Ntawv Tso Tawm:
- Tab. 1 mg, 30 pcs., Nqe txij 210 rubles
- Tab. 2 mg, 30 pcs., Nqe los ntawm 319 rubles
Cov lus qhia rau kev siv
Canonpharma (Russia) Glimepiride Canon yog ib qho txiaj ntsig zoo tshaj plaws rau kev kho mob ntawm hom 2 mob ntshav qab zib mellitus raws li glimepiride hauv kev siv tshuaj zoo ib yam. Nws yog tshuaj rau qhov tsis muaj txiaj ntsig ntawm kev noj haus thiab kev ua lub cev.
Cov analogue kim dua los ntawm 183 rubles.
Chaw tsim tshuaj paus: Krka (Slovenia)
Cov Ntawv Tso Tawm:
- Ntsiav tshuaj 60 mg, 30 pcs., Nqe los ntawm 302 rubles
- Tab. 2 mg, 30 pcs., Nqe los ntawm 319 rubles
Cov lus qhia rau kev siv
Slovenian ntsiav tshuaj npaj rau kev kho mob ntshav qab zib hom 2. Raws li cov tshuaj nquag, gliclazide siv nyob rau hauv ntau npaum ntawm 30 lossis 60 mg rau ib ntsiav tshuaj. Muaj cov contraindications thiab cov kev mob tshwm sim.
Cov analogue kim dua los ntawm 277 rubles.
Chaw tsim tshuaj paus: Beringer Ingelheim International GmbH (Lub Teb Chaws Yelemees)
Cov Ntawv Tso Tawm:
- Tab. 30 mg, 60 pcs., Nqe txij 396 rubles
- Tab. 2 mg, 30 pcs., Nqe los ntawm 319 rubles
Cov lus qhia rau kev siv
Glurenorm yog ntsiav tshuaj npaj rau kev kho mob hom 2 mob ntshav qab zib mellitus raws li glycidone hauv kev noj tshuaj ntawm 30 mg. Contraindicated nyob rau hauv hom 1 mob ntshav qab zib mellitus, lactation, cev xeeb tub, daim siab thiab mob raum. Tag nrho cov npe ntawm contraindications tuaj yeem pom nyob rau hauv cov lus qhia.
Analogs hauv kev muaj pes tsawg leeg thiab qhia txog kev siv
| Npe | Nqe hauv Lavxias | Nqe hauv Ukraine |
|---|---|---|
| Bisogamma Glyclazide | 91 rub | 182 UAH |
| Lawj Xeeb MR | -- | 92 UAH |
| Kev kuaj mob mr Gliclazide | -- | 15 UAH |
| Glidia MV Gliclazide | -- | -- |
| Glykinorm Gliclazide | -- | -- |
| Gliclazide Gliclazide | 231 rub | 57 UAH |
| Glyclazide 30 MV-Indar Glyclazide | -- | -- |
| Glyclazide-Kev Noj Qab Haus Huv Gliclazide | -- | 36 UAH |
| Glioral Glyclazide | -- | -- |
| Kev kuaj mob Gliclazide | -- | 14 UAH |
| Diazide MV Gliclazide | -- | 46 UAH |
| Osliklid Gliclazide | -- | 68 UAH |
| Diadeon gliclazide | -- | -- |
| Glyclazide MV Gliclazide | 4 RUB | -- |
Cov npe saum toj no ntawm cov yeeb tshuaj analogues, uas qhia Glidiab hloov, yog qhov tsim nyog tshaj plaws vim tias lawv muaj tib cov tshuaj sib luag thiab sib luag ua ke raws li kev taw qhia rau kev siv
Analogs los ntawm qhov taw qhia thiab cov qauv ntawm kev siv
| Npe | Nqe hauv Lavxias | Nqe hauv Ukraine |
|---|---|---|
| Glibenclamide Glibenclamide | 30 RUB | 7 UAH |
| Maninyl Glibenclamide | 54 rub | 37 UAH |
| Glibenclamide-Health Glibenclamide | -- | 12 UAH |
| Glyurenorm glycidone | 94 rub | 43 UAH |
| Amaril | 27 RUB | 4 UAH |
| Glemaz glimepiride | -- | -- |
| Glian glimepiride | -- | 77 UAH |
| Glimepiride Glyride | -- | 149 UAH |
| Glimepiride diapiride | -- | 23 UAH |
| Thaj neeb | -- | 12 UAH |
| Glimax glimepiride | -- | 35 UAH |
| Glimepiride-Lugal glimepiride | -- | 69 UAH |
| Av nplaum glimepiride | -- | 66 UAH |
| Diabrex glimepiride | -- | 142 UAH |
| Meglimide glimepiride | -- | -- |
| Melpamide Glimepiride | -- | 84 UAH |
| Perinel glimepiride | -- | -- |
| Glempid | -- | -- |
| Raug Tsim | -- | -- |
| Glimepiride glimepiride | 27 RUB | 42 UAH |
| Glimepiride-teva glimepiride | -- | 57 UAH |
| Glimepiride Canon glimepiride | 50 RUB | -- |
| Glimepiride Pharmstandard glimepiride | -- | -- |
| Dimaril glimepiride | -- | 21 UAH |
| Glamepiride diamerid | 2 RUB | -- |
Sib txawv muaj pes tsawg leeg, tuaj yeem ua ke nyob rau hauv kev taw qhia thiab cov qauv ntawm daim ntawv thov
| Npe | Nqe hauv Lavxias | Nqe hauv Ukraine |
|---|---|---|
| Avantomed rosiglitazone, metformin hydrochloride | -- | -- |
| Bagomet Metformin | -- | 30 UAH |
| Glucofage metformin | 12 RUB | 15 UAH |
| Globophage xr metformin | -- | 50 UAH |
| Reduxin Met Metformin, Sibutramine | 20 RUB | -- |
| Dianormet | -- | 19 UAH |
| Diaformin metformin | -- | 5 UAH |
| Metformin metformin | 13 RUB | 12 UAH |
| Tshuaj Metformin sandoz metformin | -- | 13 UAH |
| Siofor | 208 rub | 27 UAH |
| Formin metformin hydrochloride | -- | -- |
| Emnorm EP Metformin | -- | -- |
| Megifort Metformin | -- | 15 UAH |
| Tshuaj hlau Metformin | -- | 20 UAH |
| Tshuaj Metamin SR Metformin | -- | 20 UAH |
| Metfogamma metformin | 256 rub | 17 UAH |
| Tefor metformin | -- | -- |
| Glycometer | -- | -- |
| Glycomet SR | -- | -- |
| Tshuaj nyob | 37 RUB | -- |
| Metformin Canon metformin, ovidone K 90, pob kws hmoov txhuv, crospovidone, magnesium stearate, talc | 26 RUB | -- |
| Insuffor metformin hydrochloride | -- | 25 UAH |
| Metformin-teva metformin | 43 txhuam | 22 UAH |
| Diaformin SR metformin | -- | 18 UAH |
| Mepharmil Metformin | -- | 13 UAH |
| Metformin Yawg Liaj Ua Teb Metformin | -- | -- |
| Amaryl M Limepiride Micronized, Metformin Hydrochloride | 856 rub | 40 UAH |
| Glibomet glibenclamide, metformin | 257 rub | 101 UAH |
| Glucovans glibenclamide, metformin | 34 RUB | 8 UAH |
| Dianorm-m Glyclazide, Metformin | -- | 115 UAH |
| Dibizid-m glipizide, metformin | -- | 30 UAH |
| Douglimax glimepiride, metformin | -- | 44 UAH |
| Duotrol glibenclamide, metformin | -- | -- |
| Gluconorm | 45 rub | -- |
| Glibofor metformin hydrochloride, glibenclamide | -- | 16 UAH |
| Avandamet | -- | -- |
| Avandaglim | -- | -- |
| Janumet metformin, sitagliptin | 9 RUB | 1 UAH |
| Velmetia metformin, sitagliptin | 6026 rub | -- |
| Galvus Met vildagliptin, metformin | 259 RUB | 1195 UAH |
| Tripride glimepiride, metformin, pioglitazone | -- | 83 UAH |
| Comboglize XR metformin, saxagliptin | -- | 424 UAH |
| Comboglyz Prolong metformin, saxagliptin | 130 rub | -- |
| Gentadueto linagliptin, metformin | -- | -- |
| Vipdomet metformin, alogliptin | 55 RUB | 1750 UAH |
| Sinjardi empagliflozin, metformin hydrochloride | 240 rub | -- |
| Voglibose Oxide | -- | 21 UAH |
| Glutazone pioglitazone | -- | 66 UAH |
| Dropia Sanovel pioglitazone | -- | -- |
| Januvia sitagliptin | 1369 rub | 277 UAH |
| Galvus vildagliptin | 245 RUB | 895 UAH |
| Onglisa saxagliptin | 1472 RUB | 48 UAH |
| Nesina alogliptin | -- | -- |
| Vipidia alogliptin | 350 rub | 1250 UAH |
| Trazhenta linagliptin | 89 rub | 1434 UAH |
| Lixumia lixisenatide | -- | 2498 UAH |
| Guarem Guar cob | 9950 rub | 24 UAH |
| Insvada repaglinide | -- | -- |
| Novonorm Repaglinide | 30 RUB | 90 UAH |
| Cov Chaw Tshaj Tawm Repaglinide | -- | -- |
| Baeta Exenatide | 150 rub | 4600 UAH |
| Baeta Ntev Exenatide | 10248 rub | -- |
| Viktoza liraglutide | 8823 rub | 2900 UAH |
| Saxenda liraglutide | 1374 rub | 13773 UAH |
| Forksiga Dapagliflozin | -- | 18 UAH |
| Forsiga Dapagliflozin | 12 RUB | 3200 UAH |
| Invocana canagliflozin | 13 RUB | 3200 UAH |
| Jardins Empagliflozin | 222 RUB | 566 UAH |
| Trulicity Dulaglutide | 115 RUB | -- |
Yuav ua li cas thiaj nrhiav tau qhov pheej yig tshuaj ntawm cov tshuaj kim?
Txhawm rau kom pom qhov pheej yig cov khoom sib piv rau cov tshuaj, cov dav dav lossis cov lus sau, ua ntej txhua yam, peb pom zoo kom them sai sai rau qhov muaj pes tsawg leeg, uas yog rau tib cov tshuaj nquag thiab qhia tau rau kev siv. Cov tshuaj sib xyaw zoo ib yam ntawm cov tshuaj yuav qhia tau tias cov tshuaj cuam tshuam nrog cov tshuaj, kws tshuaj sib npaug lossis chaw muag tshuaj. Txawm li cas los xij, tsis txhob hnov qab txog qhov ua tsis muaj zog ntawm cov tshuaj uas zoo sib xws, uas tuaj yeem cuam tshuam kev nyab xeeb thiab ua haujlwm. Tsis txhob hnov qab txog cov lus qhia los ntawm cov kws kho mob, kev noj tshuaj rau nws tus kheej tuaj yeem tsim kev puas tsuaj rau koj kev noj qab haus huv, yog li nco ntsoov sab laj rau koj tus kws kho mob ua ntej siv cov tshuaj.
Sab sij huam
Muab cov kev paub dhau los ntawm gliclazide thiab lwm yam sulfonylurea derivatives, cov kev mob tshwm sim hauv qab no yuav tsum raug txiav txim siab.
Zoo li lwm yam tshuaj sulfonylurea, Diabeton® MB tuaj yeem ua rau ntshav qab zib qis thaum muaj zaub mov tsis xwm yeem thiab tshwj xeeb yog tias cov pluas noj hla dhau. Cov tsos mob tshwm sim ntawm tus mob ntshav qab zib: mob taub hau, tshaib plab, xeev siab, ntuav, ntau zog, pw tsaug zog, chim siab, ntxhov siab, tsis tshua mloog siab, ncua tshuaj tiv thaiv, kev nyuaj siab, tsis meej pem, tsis pom kev thiab hais lus, tsis meej pem, tshee, paresis, tsis hnov qab , kiv taub hau, tsis muaj zog, hnov dab tsi, khuam plhaw, ua kom zoo nkauj, ua pa tsis ua hauj lwm, poob tsaug zog, tsis nco qab nrog txoj kev txhim kho mob tsis nco qab, mus txog hnub tuag.
Cov tshuaj tiv thaiv Andrenergic tseem tuaj yeem sau tseg: nce hws, "tawv nqaij" tawv nqaij, ntxhov siab, tachycardia, ntshav tawm ntawm lub cev, mob caj pas, mob plab, lub plawv dhia tsis xis nyob thiab angina pectoris.
Raws li txoj cai, cov tsos mob hypoglycemia tau nres los ntawm kev noj cov khoom noj carbohydrates (qab zib). Noj cov khoom qab zib yog qhov ua tsis tau txiaj ntsig. Tawm tsam keeb kwm ntawm lwm cov sulfonylurea derivatives, rov qab kho cov ntshav qog ntshav tau sau tseg tom qab nws tau txais txiaj ntsig zoo.
Thaum mob ntshav qab zib tsawg los yog lub caij ntev, kev kho mob xwm txheej ceev tau qhia, tejzaum nws yuav tsum tau pw hauv tsev kho mob, txawm hais tias muaj qhov cuam tshuam los ntawm kev noj cov zaubmov nyiaj.
Lwm yam phiv
Los ntawm lub plab zom mov: mob plab, xeev siab, ntuav, raws plab, cem quav. Kev noj cov tshuaj thaum noj tshais zam cov tsos mob no lossis txo qis.
Cov kev mob tshwm sim nram qab no tsis tshua pom:
Ntawm ib feem ntawm daim tawv nqaij thiab cov nqaij mos subcutaneous: pob khaus, khaus, urticaria, erythema, maculopapular pob, ua pob ua pob.
Los ntawm cov kab mob hemopoietic: hematological ntshawv siab (anemia, leukopenia, thrombocytopenia, granulocytopenia) muaj tsawg. Raws li txoj cai, cov xwm txheej no thim rov qab yog tias kev kho tsis ua hauj lwm.
Nyob rau ib feem ntawm daim siab thiab kab mob hauv plab: nce kev ua si ntawm hepatic enzymes (AST, ALT, alkaline phosphatase), muaj qee kis - mob siab. Yog tias muaj tus mob daj ntseg cholestatic tshwm sim, kev kho yuav tsum tsis ua mus ntxiv.
Cov kev mob tshwm sim nram qab no feem ntau yuav thim rov qab yog tias kev kho tsis ua hauj lwm.
Los ntawm sab ntawm cov khoom hauv nruab nrog ntawm lub zeem muag: thaj tsam ua kom pom kev txawv txav tuaj yeem tshwm sim vim muaj kev hloov pauv hauv cov ntshav hauv cov ntshav, tshwj xeeb thaum pib kho.
Cov kev mob tshwm sim los ntawm sulfonylurea derivatives tau tshaj tawm tias mob erythrocytopenia, agranulocytosis, hemolytic anemia, pancytopenia thiab ua xua vasculitis. Tsis tas li, thaum noj lwm yam sulfonylurea derivatives, kev nce ntxiv hauv cov kev ua ntawm daim siab ua kom ntshav siab, ua haujlwm tsis zoo hauv lub siab (piv txwv li, nrog kev loj hlob ntawm cholestasis thiab jaundice) thiab mob siab raug sau tseg. Cov kev tshwm sim no tau ploj zuj zus tom qab tsis cuam tshuam txog sulfonylurea kev npaj, tab sis qee qhov xwm txheej ua rau lub siab ua rau lub siab ua haujlwm.
Sab kev tshwm sim muaj nyob rau hauv kev soj ntsuam kuaj mob
Hauv qhov kev kawm ADVANCE, muaj qhov sib txawv me me hauv qhov nquag ntawm ntau qhov xwm txheej tsis zoo ntawm ob pawg ntawm cov neeg mob. Tsis muaj cov ntaub ntawv kev nyab xeeb tshiab tau txais. Tsawg tsawg tus neeg mob tau muaj ntshav qab zib ntau ntau, tab sis qhov xwm txheej ntawm tag nrho cov neeg mob ntshav qab zib tsawg tsawg. Qhov tshwm sim ntawm cov ntshav qog nqaij hlav hauv ntshav siab glycemic tswj pab pawg tau siab dua nyob hauv pawg glycemic tswj pawg. Feem ntau qhov tshwm sim ntawm hypoglycemia nyob rau hauv kev tswj hwm glycemic tau tsom kwm tawm tsam keeb kwm ntawm cov tshuaj insulin kho.
Qhov tshuaj tiv thaiv kom paub zoo txog kev siv tshuaj DIABETON® MV
- ntshav qab zib hom 1
- ketoacidosis, mob ntshav qab zib precoma, mob ntshav qab zib coma,
- mob raum lossis mob siab tsis txaus (hauv qhov no, nws raug pom zoo kom siv cov tshuaj insulin),
- siv cov miconazole kom nruj,
- cev xeeb tub
- lactation (noj niam mis),
- hnub nyoog txog 18 xyoo
- hypersensitivity rau gliclazide lossis ib qho ntawm excipients ntawm yeeb tshuaj, lwm yam sulfonylureas, sulfonamides.
Vim tias qhov tseeb ntawm kev npaj muaj lactose, Diabeton® MB tsis pom zoo rau cov neeg mob uas tsis muaj ntshav qab zib, galactosemia, qabzib / galactose malabsorption syndrome.
Nws tsis pom zoo kom siv cov tshuaj no ua ke nrog phenylbutazone lossis danazole.
Nrog kev ceev faj, cov tshuaj yuav tsum tau siv nrog cov zaub mov tsis xwm yeem thiab / lossis tsis txaus, kev noj qabzib-6-phosphate dehydrogenase tsis txaus, cov kab mob hnyav ntawm cov hlab plawv, hypothyroidism, adrenal lossis pituitary tsis txaus, lub raum thiab / lossis lub siab tsis ua haujlwm, kev kho mob ntev nrog glucocorticosteroids, cawv, hauv cov neeg laus muaj hnub nyoog.
Kev siv tshuaj yeeb yaj kiab DIABETON® MV thaum lub sijhawm cev xeeb tub thiab lactation
Tsis muaj kev paub nrog gliclazide thaum cev xeeb tub. Cov ntaub ntawv hais txog kev siv lwm cov sulfonylurea derivatives thaum cev xeeb tub yog qhov tsawg.
Hauv kev kawm txog cov tsiaj hauv chaw sim, teratogenic cov teebmeem ntawm gliclazide tsis tau txheeb xyuas.
Txhawm rau kom txo cov kev pheej hmoo ntawm lub cev tsis xwm yeem, kev tswj hwm qib siab (kev kho kom haum) ntawm ntshav qab zib mellitus yog qhov tsim nyog.
Qhov ncauj hypoglycemic qhov ncauj thaum cev xeeb tub tsis siv. Cov tshuaj Insulin yog cov tshuaj xaiv rau kev kho mob ntshav qab zib hauv cov poj niam cev xeeb tub. Nws raug nquahu kom hloov qhov kev noj tshuaj ntawm qhov ncauj hypoglycemic nrog insulin txoj kev kho ob leeg nyob rau hauv rooj plaub ntawm kev npaj cev xeeb tub, thiab yog tias cev xeeb tub tau tshwm sim thaum noj cov tshuaj.
Ua rau hauv kev txiav txim siab tsis muaj cov ntaub ntawv hais txog kev noj cov gliclazide hauv cov kua mis thiab kev pheej hmoo ntawm kev noj qab haus huv neonatal hypoglycemia, kev pub mis niam yog contraindicated thaum kho cov tshuaj.
Cov lus qhia tshwj xeeb
Thaum sau ntawv rau tus kab mob ntshav qab zib MB, nws yuav tsum tau yug los rau hauv lub siab tias lub qog ntshav qab zib yuav tshwm sim los ntawm kev noj sulfonylurea derivatives, thiab qee kis mob hnyav thiab ntev, yuav tsum tau pw hauv tsev kho mob thiab kev tswj hwm ntawm dextrose (qabzib) ntau hnub.
Cov tshuaj tuaj yeem tsuas yog kho rau cov neeg mob uas lawv noj mov tsis tu ncua thiab suav nrog pluas tshais. Nws yog ib qho tseem ceeb heev uas yuav tsum tswj kom muaj cov roj nplej zom kom ntau txaus nrog cov zaub mov, raws li txoj kev pheej hmoo ntawm kev txhim kho hypoglycemia nce nrog cov teeb meem tsis xwm yeem lossis noj zaub mov tsis zoo, nrog rau kev noj zaub mov tsis muaj carbohydrate-cov zaub mov tsis zoo. Kev mob ntshav qab zib feem ntau pib txhim kho nrog cov zaub mov tsis muaj calorie, tom qab ua haujlwm ntev lossis ua kom ib ce muaj zog, tom qab haus cawv, lossis thaum noj ntau yam tshuaj hypoglycemic nyob rau tib lub sijhawm.
Feem ntau, cov tsos mob ntawm hypoglycemia ploj tom qab noj mov uas muaj nplua nuj hauv carbohydrates (xws li qab zib). Nws yuav tsum tau yug hauv siab tias kev noj cov khoom qab zib tsis pab tshem tawm cov tsos mob hypoglycemic. Cov kev paub ntawm kev siv lwm cov sulfonylurea derivatives qhia tau hais tias hypoglycemia tuaj yeem rov tshwm sim dua txawm tias pib kho tus mob no. Nyob rau hauv cov ntaub ntawv ntawm hypoglycemic cov lus qhia tau yog tshaj tawm lossis ua rau mob ntev, txawm tias muaj kev txhim kho ib ntus tom qab noj zaub mov nplua nuj nyob hauv carbohydrates, kev kho mob xwm txheej ceev yog tsim nyog, mus txog tsev kho mob.
Txhawm rau kom zam dhau kev txhim kho hypoglycemia, kev ceev faj xaiv cov tshuaj thiab kev noj tshuaj yog qhov tsim nyog, nrog rau kev muab tus neeg mob nrog cov ntaub ntawv tiav ntawm cov kev kho mob uas tau thov.
Ib qho kev pheej hmoo ntawm hypoglycemia ntau tuaj yeem tshwm sim hauv cov xwm txheej hauv qab no:
- kev tsis kam lossis tsis muaj peev xwm ntawm tus neeg mob (tshwj xeeb yog cov neeg laus) kom ua raws li kws kho mob tau sau tseg thiab saib xyuas nws tus mob,
- Kev noj zaub mov tsis txaus thiab tsis xwm yeem, hla zaub mov noj, yoo mov thiab hloov pauv kev noj zaub mov,
- tsis txaus ntawm kev qoj ib ce thiab tus nqi ntawm carbohydrates coj,
- lub raum tsis ua hauj lwm
- mob siab hnyav ua haujlwm
- overdose ntawm cov tshuaj Diabeton® MB,
- qee cov kab mob endocrine (mob ua cov thyroid, pituitary thiab adrenal tsis txaus),
- siv cov yeeb tshuaj ib txhij
Hepatic / Renal Tsis Ua Phem
Hauv cov neeg mob uas muaj mob hepatic thiab / lossis lub raum tsis ua haujlwm, qhov hloov pauv ntawm chaw muag tshuaj thiab / lossis chaw muag tshuaj muaj zog ntawm gliclazide yog ua tau. Kev mob ntshav nce siab uas tsim kho hauv cov neeg mob no tuaj yeem siv sijhawm ntev heev, nyob rau hauv cov xwm txheej zoo li no, yuav tsum tau kho kom sai.
Tus Neeg Mob Cov Ntaub Ntawv
Nws yog qhov yuav tsum tau ceeb toom rau tus neeg mob thiab nws tsev neeg txog qhov kev pheej hmoo ntawm kev mob ntshav qab zib, nws cov tsos mob thiab cov xwm txheej zoo rau nws txoj kev txhim kho. Yuav tsum qhia rau tus neeg mob txog cov kev pheej hmoo thiab cov txiaj ntsig zoo ntawm txoj kev kho mob uas tau thov. Tus neeg mob xav tau qhia meej txog qhov tseem ceeb ntawm kev noj haus, qhov xav tau ua kom lub cev muaj zog thiab soj ntsuam cov ntshav qabzib kom tsis tu ncua.
Kev tswj tsis tau glycemic
Kev tswj cov ntshav hauv cov neeg mob uas tau txais kev kho mob hypoglycemic yuav ua kom tsis muaj zog ntawm cov mob hauv qab no: ua npaws, mob, mob kis, lossis phais mob loj. Hauv cov xwm txheej no, nws yuav tsim nyog mus txiav kev kho mob nrog Diabeton® MB thiab muab tshuaj kho insulin.
Hauv ntau tus neeg mob, cov txiaj ntsig ntawm qhov ncauj hypoglycemic tus neeg sawv cev, suav nrog gliclazide, nyhav poob qis tom qab lub sijhawm ntev kho. Cov nyhuv no tuaj yeem yog vim ob qho kev hloov zuj zus ntawm tus kabmob thiab txo qis hauv kev kho rau cov tshuaj. Qhov tshwm sim no yog paub tias yog kev tiv thaiv tshuaj thib ob, uas yuav tsum tau qhov txawv ntawm thawj qhov, uas cov tshuaj tsis muab qhov kev cia siab tshwm sim thaum thawj zaug teem tseg. Ua ntej kuaj xyuas tus neeg mob nrog cov tshuaj tiv thaiv kab mob thib ob, nws yog qhov yuav tsum tau soj ntsuam qhov tsis txaus ntawm kev xaiv koob tshuaj thiab kev ua raws li tus neeg mob lub cev noj haus.
Soj ntsuam kuaj
Yuav kom ntsuas cov tshuaj glycemic tswj hwm, kev txiav txim siab tsis tu ncua ntawm cov ntshav ceev thiab ntshav qib glycosylated hemoglobin yog qhov pom zoo. Ib qho ntxiv, nws raug nquahu kom ua qhov kev soj ntsuam tus kheej hauv cov ntshav cov ntshav qabzib ntau.
Sulfonylurea derivatives tuaj yeem ua rau hemolytic anemia nyob rau hauv cov neeg mob uas muaj piam thaj-6-phosphate dehydrogenase tsis txaus. Txij li thaum gliclazide yog sulfonylurea derivative, kev saib xyuas yuav tsum tau ua thaum muab tshuaj rau nws rau cov neeg mob uas muaj glucose-6-phosphate dehydrogenase tsis txaus. Lub peev xwm ntawm kev muab tshuaj hypoglycemic ntawm lwm pab pawg yuav tsum raug txheeb xyuas.
Noj ntau dhau
Yog tias muaj kev noj tshuaj ntau dhau ntawm sulfonylurea derivatives, hypoglycemia yuav loj hlob tuaj.
Kev kho mob: yog tias cov tsos mob ntawm kev mob ntshav qab zib tsawg tshwm sim, koj yuav tsum tau nce cov zaub mov carbohydrates nrog zaub mov, txo qhov ntau ntawm cov tshuaj thiab / lossis hloov cov zaub mov noj. Kev ua tib zoo tshuaj xyuas tus neeg mob yuav tsum tau ua mus ntxiv kom txog thaum tus kws kho mob paub tseeb tias tus neeg mob tsis muaj kev phom sij.
Tej zaum qhov kev txhim kho ntawm cov kev mob hypoglycemic hnyav, nrog kev tsis nco qab, ntog lossis lwm yam mob puas siab ntsws. Yog tias cov tsos mob no tshwm sim, yuav tsum tau txais kev kho mob ceev ceev thiab tau mus pw hauv tsev kho mob sai.
Yog tias qhov mob ntshav qab zib ua rau tsis nco qab lossis kuaj tau, tus neeg mob txhaj tshuaj rau 50 ml ntawm 20-30% dextrose (kua nplaum) tov. Tom qab ntawd iv kua txig 10% kev daws teeb meem ntawm dextrose (kua nplaum) kom tswj tau cov concentration ntawm cov piam thaj hauv cov ntshav saum toj 1 g / L. Kev tshuaj xyuas zoo yuav tsum tau ua tsawg kawg nyob rau 48 teev tom ntej. Nyob rau yav tom ntej, nyob ntawm seb tus neeg mob lub cev, lus nug txog qhov yuav tsum tau soj ntsuam ntxiv ntawm tus neeg mob cov haujlwm tseem ceeb yuav tsum txiav txim siab.
Kev lim ntshav tsis muaj txiaj ntsig vim yog qhov tseeb khi ntawm gliclazide ntxiv rau cov ntshav protein.
Yeeb tshuaj sib cuam tshuam
Cov tshuaj uas txhim kho cov teebmeem ntawm Diabeton MB (ua rau muaj kev phom sij ntawm hypoglycemia)
Kev sib xyaw ua ke uas muaj contraindicated
Kev siv tib lub sijhawm nrog miconazole (rau kev siv thev naus laus zis thiab thaum siv cov gel ntawm qhov ncauj ntawm qhov ncauj) ua rau muaj qhov nce ntawm hypoglycemic ntawm glycazide (hypoglycemia yuav dhau mus txog thaum tsis nco qab).
Tsis pom zoo kev sib txuas ua ke
Phenylbutazone (rau kev siv mauj) txhim kho cov nyhuv hypoglycemic ntawm sulfonylurea derivatives, raws li tshem tawm lawv ntawm kev sib txuas lus nrog cov protein plasma thiab / lossis qeeb lawv qhov kev tshem tawm ntawm lub cev. Nws zoo dua yog siv lwm cov tshuaj tiv thaiv kev tiv thaiv. Yog tias phenylbutazone tsim nyog, tus neeg mob yuav tsum ceeb toom txog qhov xav tau kev tswj hwm glycemic. Yog tias tsim nyog, cov koob tshuaj ntawm cov tshuaj Diabeton® MB yuav tsum tau kho thaum noj phenylbutazone thiab tom qab nws.
Nrog rau kev siv ua ke nrog cov tshuaj Diabeton® MB, ethanol txhim kho hypoglycemia, inhibiting cov tshuaj tiv thaiv rov qab, thiab tuaj yeem pab txhawb kev txhim kho hypoglycemic coma. Nws yog ib qho tsim nyog yuav tsum tsis kam noj tshuaj, uas suav nrog ethanol, thiab los ntawm kev haus cawv.
Cov kev ceev faj tshwj xeeb
Gliclazide ua ke nrog qee yam tshuaj noj (piv txwv, lwm yam kab mob hypoglycemic - insulin, acarbose, biguanides, beta-blockers, fluconazole, ACE inhibitors - captopril, enalapril, histamine H2 receptor blockers, MAO inhibitors, sulfanilam) cov nyhuv thiab kev pheej hmoo ntawm cov ntshav qog.
Cov tshuaj uas ua rau cov nyhuv ntawm Diabeton MV (ua kom cov ntshav qab zib ntxiv)
Tsis pom zoo kev sib txuas ua ke
Danazole muaj kev pab cuam ntshav qab zib. Yog tias noj cov tshuaj no yog qhov tsim nyog, tus neeg mob tau pom zoo kom ceev glycemic tswj. Yog tias nws yuav tsum tau noj tshuaj ua ke, nws raug nquahu tias cov koob tshuaj hypoglycemic yuav tsum tau xaiv ob qho tib si thaum noj cov tshuaj danazol thiab tom qab nws tshem tawm.
Cov kev ceev faj tshwj xeeb
Kev sib xyaw ua ke ntawm Diabeton MB nrog chlorpromazine hauv kev txhaj tshuaj ntau dua (ntau dua 100 mg / hnub) tuaj yeem ua rau nce ntshav plasma glucose ntau dua vim qhov txo qis hauv insulin secretion. Ua tib zoo glycemic tswj hwm yog pom zoo. Yog tias nws yuav tsum tau noj tshuaj ua ke, nws raug nquahu tias cov koob tshuaj hypoglycemic yuav tsum xaiv ob qho tib si thaum tswj hwm kev tawm tsam thiab tom qab tshem tawm.
Nrog rau kev siv GCS ib txhij (rau kev siv tshuab hauv nroog thiab hauv zos / mob siab, txiav ntshav, ntxig qhov quav /) nce lub siab ntawm cov piam thaj hauv cov ntshav nrog kev txhim kho ntawm ketoacidosis (txo qis hauv kam rau ua rau carbohydrates). Saib xyuas glycemic tswj hwm yog pom zoo, tshwj xeeb tshaj yog thaum pib kho. Yog tias koj yuav tsum tau noj tshuaj ua ke, koj yuav tsum tau kho lub koob tshuaj hypoglycemic tus neeg sawv cev ob qho tib si thaum tswj hwm GCS thiab tom qab lawv tshem tawm.
Nrog rau kev siv ua ke ntawm beta2-adrenergic agonists (ritodrin, salbutamol, terbutaline) nce qhov kev mloog zoo ntawm cov piam thaj hauv cov ntshav. Kev saib xyuas tshwj xeeb yuav tsum tau them rau qhov tseem ceeb ntawm kev tswj hwm tus kheej-glycemic. Yog tias tsim nyog, nws raug nquahu kom hloov tus neeg mob mus rau kev kho mob insulin.
Kev sib txuas ua ke yuav tsum tau coj mus rau hauv tus account
Cov peev txheej ntawm sulfonylureas tuaj yeem txhim kho cov nyhuv ntawm anticoagulants thaum noj ua ke. Cov tshuaj tiv thaiv Anticoagulant yuav tsum tau kho kom haum.
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Cov tshuaj noj ntawm cov ntsiav tshuaj Diagnlinid
Repaglinide - cov lus qhia rau kev siv, tshuaj ntxiv, tshuaj xyuas thiab tso tawm cov qauv (0.5 mg, 1 mg thiab 2 mg ntsiav tshuaj) ntawm cov tshuaj rau kev kho mob ntawm tsis muaj tshuaj tua ntshav qab zib-tsis muaj ntshav qab zib mellitus hauv cov laus, menyuam yaus thiab thaum cev xeeb tub. ... -
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