Isofan Insulin > Cov tshuaj insulin

Hom 2 mob ntshav qab zib mellitus, theem ntawm kev tawm tsam ntawm qhov ncauj hypoglycemic, ib feem tawm tsam cov tshuaj tiv thaiv ntshav qab zib hauv qhov ncauj (kev kho ua ke), cov kab mob sib kis, kev phais mob (mono- lossis kev sib txuas ua ke), mob ntshav qab zib mellitus thaum cev xeeb tub (nrog kev kho mob tsis muaj txiaj ntsig).

Yuav siv li cas: noj ntau thiab hom tshuaj kho

P / C, 1-2 zaug hauv ib hnub, 30-45 feeb ua ntej noj tshais (hloov chaw txhaj tshuaj txhua zaus). Hauv qee kis tshwj xeeb, tus kws kho mob tuaj yeem sau ntawv rau / m txhaj tshuaj. Hauv / hauv kev qhia ntawm cov tshuaj insulin ntawm lub caij nyoog nruab nrab yog txwv! Cov koob tshuaj raug xaiv ib tus zuj zus thiab nyob ntawm cov ntsiab lus ntawm cov piam thaj hauv cov ntshav thiab zis, cov yam ntxwv ntawm chav kawm ntawm tus kabmob. Feem ntau, koob tshuaj yog 8-24 IU 1 zaug nyob rau ib hnub. Hauv cov neeg laus thiab menyuam yaus uas muaj lub siab tsis txaus siab rau insulin, qhov koob tshuaj tsawg dua 8 IU / hnub yuav txaus, rau cov neeg mob uas tsis tshua hnov mob ntau dua - ntau dua 24 IU / hnub. Ntawm qhov tshuaj txhua hnub ntau dua 0.6 IU / kg, - nyob rau hauv daim ntawv ntawm 2 koob nyob hauv qhov chaw sib txawv. Cov neeg mob tau txais 100 IU lossis ntau dua toj ib hnub, thaum hloov cov tshuaj insulin, nws raug nquahu kom mus pw hauv tsev kho mob. Hloov pauv los ntawm ib qho tshuaj rau lwm tus yuav tsum tau ua nyob rau hauv kev tswj hwm ntawm cov ntshav qabzib.

Pharmacological kev txiav txim

Nruab nrab-insulin. Txo cov concentration ntawm cov piam thaj hauv cov ntshav, ua rau nws nqus tau los ntawm cov ntaub so ntswg, txhim kho lipogenesis thiab glycogenogenesis, ua kom muaj protein ntau, txo tus nqi ntawm cov piam thaj los ntawm daim siab.

Nws cuam tshuam nrog ib qho kev tshwj xeeb ntawm sab nraud daim nyias nyias ntawm cov hlwb thiab ua ib qho insulin receptor complex. Los ntawm kev ua kom coj los ua ke ntawm CAMP (hauv cov roj ntsha thiab lub siab hlwb) lossis nkag ncaj qha rau hauv lub cell (leeg), insulin receptor complex stimulates intracellular processes, suav nrog synthesis ntawm cov lej ntawm cov enzymes tseem ceeb (hexokinase, pyruvate kinase, glycogen synthetase, thiab lwm yam). Cov thawj coj hauv cov ntshav nyob rau hauv lub cev vim qhov nce ntawm nws txoj kev thauj mus los ntau dua, kev nqus thiab kev pov tseg ntau ntawm cov nqaij mos, ua kom cov lipogenesis, glycogenogenesis, synthesis protein, txo tus nqi ntawm cov piam thaj los ntawm lub siab (txo qis ntawm cov khoom ntawm glycogen), thiab lwm yam.

Tom qab sc txhaj tshuaj, cov nyhuv tshwm sim hauv 1-1.5 teev. Qhov ua tau zoo tshaj plaws yog nyob rau hauv qhov sib xyaw nruab nrab ntawm 4-12 teev, lub sijhawm ua haujlwm yog 11-24 teev, nyob ntawm qhov muaj pes tsawg leeg ntawm insulin thiab koob tshuaj, qhia txog qhov cuam tshuam rau sab hauv thiab sab hauv ntawm kev coj tus kheej.

Sab sij huam

Kev tsis haum tshuaj (urticaria, angioedema - ua npaws, ua tsis taus pa, ua pa tsis txaus),

hypoglycemia (pallor ntawm daim tawv nqaij, nce tawm hws, tawm hws, palpitations, tshee tshee, tshaib plab, ntxhov siab, ntxhov siab, mob plab hauv lub qhov ncauj, mob taub hau, tsaug zog, pw tsaug zog, ntshai, poob siab, chim siab, coj tus cwj pwm txawv, tsis muaj zog, hais lus thiab hais lus tsis meej thiab qhov pom kev), hypoglycemic coma,

hyperglycemia thiab ntshav qab zib acidosis (ntawm kev txhaj tshuaj qis, hla kev txhaj tshuaj, kev noj zaub mov tsis zoo, nrog kub cev thiab mob kis): tsaug zog, nqhis dej, tsis qab los noj mov, ntsej muag tawm ntsej muag),

hnov tsis nco qab (txog rau kev txhim kho ntawm precomatose thiab coma),

pom kev tsis pom kev tsis zoo (feem ntau thaum pib kho mob),

txhaj tshuaj tiv thaiv kab mob hla nrog tib neeg cov tshuaj insulin, nce ntxiv ntawm lub titer ntawm cov tshuaj tiv thaiv cov tshuaj insulin, tom qab ntawd nce glycemia,

hyperemia, khaus thiab lipodystrophy (mob atrophy lossis hypertrophy ntawm subcutaneous rog) ntawm qhov chaw txhaj tshuaj.

Thaum pib ntawm kev kho mob - edema thiab hnov mob tsis zoo (yog ib ntus thiab ploj mus nrog kev kho mob txuas ntxiv). Cov tsos mob: hws, palpitations, tshee tshee, tshaib plab, ntxhov siab, teeb tsa hauv lub qhov ncauj, pallor, mob taub hau, tsaug zog, pw tsaug zog, ntshai, siab ntsws xav, chim siab, txawv txav, tsis muaj zog, hais lus thiab tsis pom kev, hypoglycemic coma, nriaj.

Kev Kho Mob: yog tias tus neeg mob nco qab, nws tau txiav txim siab dextrose qhov ncauj, s / c, i / m lossis iv txhaj tshuaj glucagon lossis iv hypertonic dextrose tov. Nrog rau kev txhim kho lub ntsej muag tsis nco qab, 20-40 ml (txog 100 ml) ntawm 40% dextrose tov yog txhaj iv rau hauv qhov dej kom txog thaum tus neeg mob tawm ntawm lub cev tsis nco qab.

Cov lus qhia tshwj xeeb

Ua ntej yuav siv tshuaj insulin los ntawm vial, nws yog qhov tsim nyog los xyuas qhov ntsuas ntawm kev daws. Thaum lub cev txawv teb chaws tshwm sim, tuav los yog nag lossis daus ntawm cov tshuaj rau ntawm lub khob ntawm lub raj mis, tsis tuaj yeem siv tshuaj daws teeb meem.

Qhov kub ntawm cov tshuaj insulin yuav tsum nyob ntawm chav sov.

Qhov koob tshuaj insulin yuav tsum tau kho nyob rau hauv cov kis mob kis, thaum tsis ua haujlwm ntawm cov thyroid caj pas, Addison's disease, hypopituitarism, mob raum tsis ua haujlwm thiab ntshav qab zib mellitus hauv cov neeg muaj hnub nyoog 65 xyoos.

Cov laj thawj ntawm kev ua ntshav siab tuaj yeem yog: kev noj tshuaj insulin ntau dhau, hloov tshuaj, hla zaub mov, ntuav, raws plab, kev ntxhov siab ntawm lub cev, cov kab mob uas txo qis qhov xav tau ntawm insulin (kab mob siab ntawm lub raum thiab mob siab, nrog rau kev ua haujlwm ntawm adrenal cortex, pituitary lossis thyroid caj pas), hloov chaw kev txhaj tshuaj (piv txwv, daim tawv nqaij ntawm lub plab, xub pwg, ncej puab), ntxiv rau kev sib cuam tshuam nrog lwm yam tshuaj. Nws muaj peev xwm ua kom txo qis ntawm cov piam thaj hauv cov ntshav thaum hloov mus rau tus neeg mob los ntawm tsiaj insulin mus rau tib neeg cov insulin. Qhov hloov ntawm tus neeg mob mus rau tib neeg cov kua dej yuav tsum tau ua kev tu mob ib txwm muaj thiab tsuas yog ua los ntawm kev saib xyuas ntawm kws kho mob.

Kev ntsuam xyuas kev txhim kho hypoglycemia tuaj yeem cuam tshuam cov peev xwm ntawm cov neeg mob koom tes hauv kev khiav tsheb, nrog rau kev saib xyuas cov tshuab thiab tshuab.

Cov neeg mob ntshav qab zib tuaj yeem txwv cov ntshav qab zib tsawg uas lawv xav los ntawm kev noj cov piam thaj lossis zaub mov ntau hauv carbohydrates (Nws raug nquahu kom koj ib txwm muaj tsawg kawg 20 g suab thaj nrog koj). Hais txog qhov hloov ntshav qog ntshav qab zib, nws yog qhov yuav tsum tau qhia rau tus kws kho mob uas tuaj koom nrog txiav txim siab txog qhov xav tau ntawm kev kho kho. Thaum cev xeeb tub, nws yog ib qho tsim nyog yuav tsum coj mus rau hauv tus lej txo qis (kuv plaub hlis) lossis nce ntxiv (II-III trimesters) ntawm cov tshuaj insulin. Thaum lub sijhawm thiab yug tom qab yug, insulin yuav tsum poob ntau. Thaum lub sijhawm lactation, kev soj ntsuam txhua hnub yog xav tau rau ntau lub hlis (txog thaum qhov xav tau cov tshuaj insulin yuav ruaj khov).

Kev sib txuam

Cov tshuaj tsis sib haum nrog kev daws teeb meem ntawm lwm cov tshuaj.

Cov nyhuv hypoglycemic yog txhim kho los ntawm sulfonamides (suav nrog qhov ncauj tshuaj hypoglycemic, sulfonamides), MAO inhibitors (suav nrog furazolidone, procarbazine, selegiline), carbonic anhydrase inhibitors, ACE inhibitors, NSAIDs (suav nrog salicylates), anabolic (suav nrog stanozolol, oxandrolone, methandrostenolone), androgens, bromocriptine, tetracyclines, clofibrate, ketoconazole, mebendazole, theophylline, cyclophosphamide, phenfluramine, Li + kev npaj, pyridoxine, quinidine, quinine, chloroquinine.

Glucagon, somatropin, corticosteroids, tshuaj tiv thaiv qhov ncauj, estrogens, thiazide thiab voj diuretics, BMKK, cov thyroid hormones, heparin, sulfinpyrazone, sympathomimetics, danazole, tricyclic antidepressants, clonidinin, calcitonin, antonidinotin, antagonists, ankylrogen, antagonists, cov tshuaj tiv thaiv kab mob, antonium epinephrine, H1-histamine receptor blockers.

Beta-blockers, reserpine, octreotide, pentamidine tuaj yeem txhim kho ob qho tib si thiab ua kom cov nyhuv tsis muaj zog hypoglycemic ntawm insulin.

Kev qhia rau kev siv thiab cov npe lag luam ntawm cov tshuaj

Kev siv cov tshuaj yog qhia rau cov tshuaj insulin-tiv thaiv mob ntshav qab zib. Ntxiv mus, txoj kev kho yuav tsum kav tag lub neej.

Cov tshuaj insulin li Isofan yog tib neeg cov tshuaj tiv thaiv ua tsis taus pa hauv cov tshuaj xws li:

ntshav qab zib hom 2 (insulin-dependant),
kev phais mob
tsis kam tiv thaiv cov kab mob ntshav qab zib ua qhov ncauj ntawm txoj kev kho mob,
mob ntshav qab zib hauv plab (tsis muaj kev ua tau zoo ntawm kev noj zaub mov),
intercurrent pathology.

Cov tuam txhab kws tsim khoom lag luam tsim cov tib neeg cov tshuab hluav taws xob ua kom insulin nyob rau hauv ntau lub npe. Cov neeg nyiam tshaj plaws yog Vozulim-N, Biosulin-N, Protafan-NM, Insuran-NPH, Gensulin-N.

Lwm hom isofan insulin kuj tseem siv nrog cov npe lag luam nram qab no:

Ntsuas Yuam Kev
Humulin (NPH),
Pensulin,
Isofan insulin NM (Protafan),
Actrafan
Saib tsis muaj N,
Biogulin N,
Protafan-NM Penifill.

Nws yog tsim nyog sau cia tias kev siv ib qho lus siv rau Insulin Isofan yuav tsum pom zoo nrog kws kho mob.

Tsuas tshuaj thiab tswj hwm

Cov lus qhia rau kev siv nrog insulin Isofan hais tias nws feem ntau ua rau subcutaneously txog 2 zaug hauv ib hnub ua ntej noj tshais (30-45 feeb). Hauv qhov no, koj yuav tsum hloov thaj chaw txhaj tshuaj txhua hnub thiab khaws cov koob txhaj tshuaj uas siv los ntawm chav kub, thiab ib qho tshiab hauv lub tub yees.

Qee zaum cov tshuaj tau muab tshuaj intramuscularly. Thiab txoj hauv kev siv qhov tseeb nruab nrab ntawm kev siv tshuaj insulin yog qhov siv tsis tau siv.

Qhov ntau npaum li cas tau muab xam ib qho zuj zus rau txhua tus neeg mob, raws li theem ntawm cov suab thaj hauv kev tso zis lom thiab qhov tshwj xeeb ntawm tus kab mob. Raws li txoj cai, qhov nruab nrab txhua hnub ntau npaum li cas los ntawm 8-24 IU.

Yog tias cov neeg mob tau mob siab tsis txaus rau cov tshuaj insulin, ces qhov niaj hnub noj tshuaj ntau yog 8 IU. Nrog kev ua tsis tau zoo ntawm cov tshuaj hormones, qhov tshuaj ntau ntau ntxiv - los ntawm 24 IU ib hnub.

Thaum lub ntim txhua hnub ntawm cov tshuaj ntau dua 0.6 IU rau 1 kg ntawm huab hwm coj, tom qab ntawd 2 hno yog tsim nyob rau hauv qhov sib txawv ntawm lub cev. Cov neeg mob uas noj tshuaj ib hnub ib zaug ntawm 100 IU lossis ntau dua yuav tsum tau mus pw hauv tsev kho mob yog tias hloov cov kua dej.

Ntxiv mus, thaum hloov los ntawm ib hom khoom lag luam mus rau lwm tus, nws yog qhov yuav tsum tau soj ntsuam cov piam thaj hauv qab.

Kev phiv tshuaj thiab kev haus ntau dhau

Kev siv cov tshuaj insulin rau tib neeg tuaj yeem ua rau ua xua tuaj. Feem ntau, nws yog angioedema (hypotension, ua pa luv, kub cev) thiab urticaria.

Tsis tas li, ntau tshaj qhov ntau npaum li cas tuaj yeem ua rau lub qog ntshav qab zib, los ntawm cov tsos mob hauv qab no:

insomnia
daim tawv nqaij blanching,
kev nyuaj siab
hyperhidrosis
ntshai
zoo siab lub xeev
palpitations
mob taub hau
tsis meej pem,
vestibular kev ntshawv siab
kev tshaib kev nqhis
tshee hnyo thiab os.

Cov kev mob tshwm sim suav nrog cov ntshav qab zib acidosis thiab hyperglycemia, uas tau tshwm sim los ntawm lub ntsej muag yaug, kev tsaug zog, tsis qab los noj mov thiab nqhis dej. Feem ntau, cov xwm txheej zoo li no tiv thaiv keeb kwm ntawm kev kis tus kab mob thiab kub taub hau, thaum txhaj tshuaj tsis dhau, qhov tsuas tshuaj tsis yog, thiab yog tias kev noj haus tsis ua raws.

Qee lub sij hawm ua txhaum ntawm nco qab tshwm sim. Nyob rau hauv qhov teeb meem nyuaj, ib qho tab tom zoo thiab xeev tsis xeev tau nce qib.

Thaum pib ntawm kev kho, kev hloov pauv tsis ua haujlwm nyob rau hauv kev ua haujlwm pom tau. Ib qho kev nce ntxiv ntawm lub titer ntawm anti-insulin lub cev tseem tseem sau tseg nrog kev nruam ntej ntawm glycemia thiab cov tshuaj tiv thaiv kab mob ntawm cov xwm txheej hla nrog tib neeg insulin.

Feem ntau qhov chaw txhaj tshuaj swells thiab khaus. Hauv qhov no, subcutaneous fatty cov ntaub so ntswg hypertrophies lossis atrophies. Thiab nyob rau theem pib ntawm txoj kev kho, kev ua yuam kev tsis txaus ntseeg ib ntus thiab mob edema yuav tshwm sim.

Yog tias muaj kev noj tshuaj ntau dhau ntawm cov tshuaj hormones, cov ntshav qab zib cov ntshav yuav poob qis. Qhov no ua rau cov ntshav qog ua kom qis, thiab qee zaum tus neeg mob poob rau hauv lub xeev tsis xeev.

Yog tias cov koob tshuaj tau nce siab dua me ntsis, koj yuav tsum noj cov zaub mov uas muaj cov carb ntau (chocolate, qhob cij dawb, ib yob, khaub noom) lossis haus dej qab zib. Thaum tsaus muag, qhov dextrose tov (40%) lossis glucagon (s / c, v / m) tau muab rau tus neeg mob hauv / hauv.

Thaum tus neeg mob rov qab nco qab, nws yog qhov tsim nyog los pub nws cov zaub mov nplua nuj hauv kev ua si carbohydrates.

Qhov no yuav tiv thaiv hypoglycemic rov mob dua thiab glycemic coma.

Nws yuav ua haujlwm li cas

Isofan insulin cov tib neeg kev tsim kho tshuab muaj feem xyuam rau lub cev, ua kom muaj qhov tshwm sim hypoglycemic. Cov tshuaj no nkag los rau hauv kev sib cuag nrog cytoplasmic receptors ntawm lub cell membrane. Qhov no tsim cov insulin receptor complex. Nws lub luag haujlwm yog ua kom cov metabolism hauv kev ua haujlwm uas tshwm sim hauv cov hlwb lawv tus kheej, nrog rau kev pabcuam hauv kev sib txuas ntawm lub ntsiab ntawm txhua tus enzymes uas twb muaj lawm.

Txo cov piam thaj hauv cov ntshav yuav tshwm sim los ntawm kev nce ntxiv hauv kev thauj mus los hauv lub cell, nrog rau kev txo cov piam thaj ntau lawm, los ntawm kev pab hauv cov txheej txheem ntawm kev nqus. Lwm qhov zoo dua ntawm tib neeg cov kua dej yog cov synthesis protein, ua kom cov lithogenesis, glycogenogenesis.

Lub sijhawm ntev npaum li cas ntawm cov tshuaj no ua rau ncaj qha sib piv rau tus nqi ntawm nqus ntawm cov tshuaj mus rau hauv cov ntshav, thiab cov txheej txheem nqus tau yog nyob ntawm tus qauv ntawm kev coj thiab qhov tshuaj ntawm cov tshuaj. Yog li, cov nyhuv ntawm cov tshuaj no nws txawv rau cov neeg mob sib txawv.

Kev lig kev cai, tom qab txhaj tshuaj, cov nyhuv ntawm cov tshuaj pib tom qab 1.5 teev. Lub ncov ntawm qhov ua tau tshwm sim nyob rau ntawm taw tes 4 teev tom qab tswj hwm kev siv tshuaj. Lub sijhawm ua haujlwm yog 24 teev.

Qhov nqus ntawm Isofan nyob ntawm cov hauv qab no:

Qhov chaw txhaj tshuaj (pob tw, plab, ncej puab),
Kev siv tshuaj nquag
Koob tshuaj.

Cov tshuaj no yog tawm los ntawm lub raum.

Yuav siv li cas: kev taw qhia rau kev siv

Raws li cov lus qhia rau kev siv Isofan, nws yuav tsum muab tshuaj subcutaneously ob zaug ib hnub: thaum sawv ntxov thiab yav tsaus ntuj ua ntej noj mov (30-40 feeb ua ntej noj mov). Qhov chaw txhaj tshuaj yuav tsum tau hloov txhua txhua hnub, cov koob txhaj tshuaj yuav tsum khaws cia li qub, qhov kub thiab txias, thiab qhov tshiab yuav tsum nyob hauv ntim, hauv tub yees. Tsis tshua muaj, qhov tshuaj no tau txhaj rau hauv cov leeg, tab sis yuav luag tsis tuaj yeem, vim tias nws yog insulin nruab nrab.

Cov koob tshuaj ntawm cov tshuaj no tau muab xam rau txhua tus neeg los ntawm kev mob ntshav qab zib, hauv kev sab laj nrog tus kws kho mob uas koom nrog. Ua raws li cov piam thaj hauv ntshav thiab qhov tshwj xeeb ntawm ntshav qab zib. Qhov nruab nrab txhua hnub koob tshuaj, ib txwm coj sib txawv ntawm 8-24 IU.

Thaum muaj qhov mob hypersensitivity rau insulin, nws yog ib qho tsim nyog yuav tsum tsis txhob ntau dua 8 IU ib hnub, yog tias qhov tshuaj hormones tsis pom zoo, qhov tshuaj yuav nce ntxiv rau 24 lossis ntau dua IU thaum nruab hnub. Yog tias qhov tshuaj txhua hnub ntawm cov tshuaj yuav tsum dhau 0. 6 IU toj ib phaus ntawm lub cev qhov hnyav ntawm tus neeg mob, ces 2 qhov kev txhaj tshuaj ib zaug nyob rau ntau qhov chaw.

Urticaria,

Kev noj tshuaj ntau dhau ntawm cov tshuaj no yog fraught nrog cov ntshav qab zib tsawg thiab tsis nco qab. Tshaj cov koob tshuaj tuaj yeem tiv thaiv yog tias koj noj cov khoom noj uas muaj carbohydrates (chocolate, khaub noom, khaub noom, ncuav qab zib).

Yog tias tsis nco qab, ib qho kev daws teeb meem ntawm Dextrose lossis Glucagon yuav tsum tau txhaj tshuaj rau tus neeg mob kom ncaj. Thaum lub siab nco qab rov qab, tus neeg mob yuav tsum tau muab zaub mov kom ntau hauv carbohydrates. Qhov no yuav ua rau nws ua tau kom zam ob qho mob glycemic coma thiab hypoglycemic relapse.

Insulin-isophan: cov lus qhia rau kev siv ncua kev ncua

Lub npe Latin: tshuaj insulinum isophanum
ATX Code: A10a
Yam tshuaj muaj sia: tshuaj insulin-tib neeg kev tsim kho tshuab isophane

Chaw tsim tshuaj paus: Novo Nordisk, Denmark

Mob ntawm lub tsev muag tshuaj: Los ntawm tshuaj
Cia rau cov neeg mob: t li ntawm 2-8 qib
Hnub tas sij hawm: 2 xyoos

Tib neeg kev tsim kho tshuab ua kua tshuaj isulin yog siv los kho cov mob uas cuam tshuam nrog kev tsim tsis txaus ntawm lub cev lub cev lawm los ntawm cov tshuaj insulin. Tsis muaj ib lub yeeb tshuaj nrog cov npe no ntawm kev muag, vim qhov no yog ib hom tshuaj uas dhia, tab sis muaj analogues. Qhov piv txwv tiag tiag ntawm cov khoom muaj nyob rau ntawm kev muag yog rinsulin.

Isofan insulin: Kuv tuaj yeem siv nrog lwm cov tshuaj

Tsub kom muaj cov nyhuv hypoglycemic (ib txwm muaj ntshav qab zib) Isofan tus kab mob nrog:

Sulfonamides,
Chloroquinine
ACE inhibitors / MAO / carbonic anhydrase,
Ethanol
Mebendazole,
Txhais tau tias yog ib feem ntawm pawg neeg anabolic steroids,
Fenfluramine
Cov tshuaj Tetracycline
Clofibrate
Cov tshuaj ntawm theophylline pab pawg.

Cov nyhuv hypoglycemic (nqa cov suab thaj hauv cov ntshav mus rau li qub) tau txo qis vim yog cov kab mob ntawm Isofan nrog cov tshuaj zoo li no:

Somatropin
Epinephrine
Cov Txheej Txheem
Epinephrine
Phenytoin
Calcium antagonists.

Cov piam thaj hauv cov ntshav tsawg dua vim qhov mob tshwm sim ntawm insulin Isofan nrog thiazide thiab lub voj diuretics, nrog BMCC, ntxiv rau cov thyroid hormones, sympathomimetics, Klondin, Danazole, sulfinpyrazone. Morphine, yeeb tshuaj xas, dej cawv thiab nicotine kuj txo cov ntshav qab zib. Cov neeg mob ntshav qab zib yuav tsum tsis txhob haus luam yeeb lossis haus luam yeeb.

Ntxiv nrog rau kev tswj hwm ntawm cov tshuaj tsis haum nrog Isofan, lwm yam xws li tuaj yeem ua rau cov ntshav qog ntshav qab zib ib yam nkaus:

Hloov mus rau lwm cov tshuaj uas tswj cov qib qab zib kom zoo,
Mob ntshav qab zib ntuav
Mob ntshav qab zib-ua rau mob raws plab
Lub cev nce thauj khoom
Cov kab mob uas txo qis qhov xav tau ntawm cov tshuaj insulin (pituitary, hypothyroidism, lub siab ua haujlwm, lub raum tsis ua haujlwm),
Thaum tus neeg mob tsis noj mov raws sijhawm,
Hloov chaw txhaj tshuaj.

Cov koob tshuaj tsis yog lossis lub sijhawm ntev dhau los ntawm kev txhaj tshuaj tuaj yeem ua rau hyperglycemia (tshwj xeeb tshaj yog cov ntsiab lus ntawm tus kabmob ntshav qab zib hom 1). Yog tias qhov kev kho kom tsis haum rau lub sijhawm, tus neeg mob yuav poob mus rau hauv lub cev tsis nco qab ketoacidotic.

Tus neeg mob uas siv cov tshuaj no yog hnub nyoog laus dua rau caum xyoo, thiab tseem muaj ntau dua yog li leej twg muaj kev ua haujlwm tsis zoo ntawm cov thyroid caj pas, lub raum, lossis mob siab, nws yog qhov yuav tsum tau sab laj nrog tus kws kho mob uas tau kawm txog kev noj tshuaj ntawm insulin Isofan. Yuav tsum muaj kev ntsuas ib yam nkaus yog tias tus neeg mob cuam tshuam los ntawm hypopituitarism lossis Addison tus kab mob.

Yuav ua li cas stab: cov lus qhia tshwj xeeb

Ua ntej koj noj cov tshuaj mus rau hauv cov phwj hauv qab, xyuas seb qhov kev daws teeb meem yog pos huab. Nws yuav tsum ua kom pob tshab. Yog tias plaub ya ri, lub cev txawv teb chaws tau tshwm sim, txoj kev daws teeb meem tau ua huab, ib qho nag lossis daus tau tsim, cov tshuaj tsis tuaj yeem siv.

Qhov kub ntawm cov tshuaj tso cai yuav tsum yog chav kub. Yog tias koj tam sim no muaj mob khaub thuas lossis ntau dua nrog lwm yam kev kis mob, koj yuav tsum sab laj nrog koj tus kws kho mob txog kev noj tshuaj. Thaum hloov cov tshuaj, qhov no yuav tsum tau ua nyob rau hauv kev saib xyuas ntawm tus kws kho mob, nws yog ib qho tsim nyog mus rau hauv tsev kho mob.

Cev xeeb tub, lactation thiab insulin Isofan

Cov poj niam cev xeeb tub uas muaj ntshav qab zib tuaj yeem noj Isofan insulin, nws yuav tsis tuaj yeem ncav cuag tus me nyuam hauv lub plab. Koj tuaj yeem siv nws thiab cov niam tu, yuam kom nyob nrog tus kab mob no. Nws yog ib qho tseem ceeb kom paub tias thaum cev xeeb tub hauv thawj peb lub hlis, xav tau cov tshuaj insulin tsawg dua, thiab nyob rau lub hlis thib ob thiab thib peb nce ntxiv.

Kev ntsuas rau siv

Qhov tseem ceeb tshaj plaws yog kev kho mob ntshav qab zib hom 1, tab sis qee qhov nws tuaj yeem tsim kho nyob rau hauv lub cev muaj kev tiv thaiv kev ywj pheej ntawm tus kab mob. Txhua lub npe lag luam rau isophane yog qhov tsim nyog rau kev kho mob ntawm tus neeg uas tsis noj tshuaj hypoglycemic vim tias ua tiav lossis ib nrab tsis kam. Tsawg tsawg dua, kev siv tshuaj kho mob siv rau hauv cov poj niam cev xeeb tub muaj hom mob ntshav qab zib zaum ob.

Kev Sau thiab tso cov foos

1 ml ntawm kev daws muaj 100 chav nyob ntawm cov tshuaj nquag nquag. Ntu cov khoom siv - protamine sulfate, dej tsis huv rau kev txhaj tshuaj, crystalline phenol, sodium dihydrate phosphate, glycerol, metacresol.

Raug tshem tawm rau kev txhaj tshuaj, pob tshab. Ib lub raj mis muaj 3 ml ntawm cov tshuaj. Hauv ib pob muaj 5 daim cartridges lossis nws muag hauv ib lam fwj tam sim ntawd 10 ml ntawm cov tshuaj.

Kho thaj chaw

Isofan insulin yog nruab nrab ncua sijhawm ntawm kev nqis tes ntawm ib tus neeg sawv cev hypoglycemic, uas tau ua siv cov thev naus laus zis DNA thev naus laus zis.

Tom qab kev tswj hwm subcutaneous, cov tshuaj hormones endogenous khi rau cov insulin receptor complex, uas ua rau cov synthesis ntawm ntau cov enzyme tebchaw - hexokinase, pyruvate kinase thiab lwm tus.

Ua tsaug rau cov tshuaj qhia los ntawm sab nraud, qhov chaw nyob ntawm qog ntau ntxiv, vim tias nws tau siv lub zog ntau heev los ntawm cov ntaub so ntswg, thiab tus nqi ntawm cov suab thaj ua ke los ntawm daim siab yog txo qis. Nrog rau kev siv ntau zaus, cov tshuaj tawm ua rau cov txheej txheem ntawm lipogenesis, glycogenogenesis thiab proteinogenesis.

Lub sijhawm ntawm qhov kev txiav txim thiab tus nqi ntawm qhov pib ntawm cov nyhuv hauv cov neeg sib txawv nyob ntawm ntau yam, tshwj xeeb ntawm kev ceev ntawm cov metabolism hauv cov txheej txheem. Nws txhais li cas - txoj kev no yog ib leeg.

Qhov nruab nrab, vim tias qhov no yog qhov tshuaj hormones ntawm qhov nruab nrab ntawm qhov kev txiav txim siab, qhov pib ntawm cov nyhuv tshwm sim tsis dhau ib teev thiab ib nrab los ntawm lub sijhawm ntawm subcutaneous tswj hwm.

Lub sijhawm ntawm cov nyhuv yog 24 teev, kev pom siab siab tshwm sim nyob rau hauv 4-12 teev.

Cov tshuaj no yog nqus tsis ncaj, ua tawm ntawm lub raum, qhov hnyav ntawm cov nyhuv yog ncaj qha rau ntawm qhov chaw txhaj tshuaj (plab, caj npab lossis ncej puab). Cov tshuaj tsis hla cov teeb meem placental thiab mus rau niam mis, yog li ntawd nws raug tso cai rau cov niam cev xeeb tub thiab cov menyuam nyuam qhuav yug los tshiab.

Txoj kev ntawm daim ntawv thov

Tus nqi nruab nrab ntawm cov tshuaj hauv Lavxias yog 1075 rubles rau ib pob.

Txhawm rau txhaj tshuaj subcutaneously, ib hnub ib zaug, nyob rau ntau qhov chaw. Qhov ntau zaus ntawm kev txhaj tshuaj hauv ib qho chaw yuav tsum tsis pub ntau tshaj 1 zaug hauv ib hlis, yog li qhov chaw tswj hwm ntawm cov tshuaj hloov txhua lub sijhawm.

Ua ntej siv ncaj qha, ampoules tau dov rau hauv lub xib teg.

Cov lus qhia kev txhaj tshuaj yooj yim - kev kho kom tsis muaj mob, cov koob tau ntxig subcutaneously ntawm kaum ntawm 45 degrees rau hauv lub clamped quav, tom qab ntawd qhov chaw huv huv tshuaj tua kab. Cov koob tshuaj yog xaiv los ntawm tus kws kho mob ib leeg zuj zus.

Thaum cev xeeb tub thiab pub niam mis

Cov tshuaj tau pom zoo rau siv thaum lub sijhawm no.

Cov Kev Tsis Txaus Ntseeg thiab Kev Ceev Faj

Cov no suav nrog: tsis nkag rau qee yam khoom muaj nqis thiab muaj suab thaj tsawg tsawg nyob rau ib lub sijhawm tshwj xeeb.

Hla kev sib txuam yeeb tshuaj

Txo cov nyhuv ntawm cov tshuaj: cov kab ke glucocorticoids, qhov ncauj tsis huv, estradiol thiab progesterone, anabolic steroids, diuretics, antidepressants, cov thyroid hormones.

Ua kom muaj txiaj ntsig: cawv, salicylates, sulfonamides thiab beta-blockers, MAO inhibitors.

Phiv thiab haus tshaj

Hypoglycemia los yog lipodystrophy yog ua tau yog tias txoj cai txhaj tshuaj thiab qhov tshuaj muab rau noj tsis ua raws. Tsawg dua yog qhov cuam tshuam rau lub cev rau hauv txoj kev tsis haum, ua pa luv, txo ntshav siab, hyperhidrosis thiab tachycardia.

Yog tias muaj kev noj ntau dhau, cov tsos mob ntawm cov ntshav qab zib tsawg tshwm sim: muaj kev xav txog kev tshaib plab, tsis muaj zog, tsis nco qab, kiv taub hau, tawm hws, xav noj cov khoom qab zib, nyob rau hauv mob hnyav - tsis nco qab lawm. Cov tsos mob me yog tso tseg los ntawm kev ua kom tau sai ntawm cov roj sai, nruab nrab - nrog los ntawm dextrose lossis qabzib. Cov xwm txheej hnyav yuav tsum hu rau cov kws kho mob hauv tsev sai.

Rinsulin PNH

Geropharm-bio LLC, Russia

Tus nqi nruab nrab nyob rau hauv Russia - 1000 rubles rau ib pob.

Rinosulin yog cov tshuaj tiv thaiv tag nrho thiab muaj cov tshuaj insulin isophan nruab nrab-ntev. Daim ntawv foos no zoo vim tias nws tsis tas yuav tsum tau tswj tuav kab lis kev cai ntau.

Pros:

Txij nkawm
Lavxias teb sab ntau lawm.

Cons:

Tsis yog qhov pheej yig
Phiv ntau yam ua tau.

Humulin NPH

Eli Lilly East, Switzerland

Tus nqi nruab nrab nyob rau hauv Russia - 17 rubles.

Humulin NPH yog kev sib piv ntawm qhov nruab nrab ntawm tus nqi nruab nrab.

Pros:

Tus nqi qis
Yooj yim siv.

Cons:

Muaj cov kev mob tshwm sim
Tsis haum rau txhua tus.

Tag nrho cov ntaub ntawv hais txog Biosulin N ntawm Pharmacy.ru

Koj txuag tau 104.00 rub.

rau 1 tsev - 183,00 rub.

Koj txuag tau 49.00 rub.

rau 1 tsev - 438,00 rub.

Koj txuag 99,00 rub.

rau 1 tsev - 256,00 rub.

Pharmstandard-Ufa Vitamin Cog, JSC Lavxias Kev Ntshav Qab Zib Txhais

Tus neeg sawv cev hypoglycemic, nruab nrab insulin.

Tso Tawm Cov Ntawv

5 ml - fwj ntawm cov iav tsis muaj kob (1) - ntim. 5 ml - ntim ntawm cov iav tsis muaj kob (2) - contour cell ntim (1) - ntim. 5 ml - flasks ntawm cov iav tsis muaj kob (3) - blister ntim cov txim rau kev ncua rau kev tswj hwm ntawm 100 IU / ml - 3 ml ntawm kev npaj rau hauv lub voos xwm txheej ntawm cov xim tsis nruab nrab lub khob, ntim nrog lub hau ntim, rau siv nrog Biomatic Pen cwj mem-ncua kev tswj hwm rau ntawm 100 ME / ml - 3 ml ntawm cov tshuaj nyob rau hauv pob ntawv ntawm tsis muaj xim nruab nrab iav, kaw nrog lub hau ntim. Lub cartridge yog ntsia rau hauv BiomatikPen 2 rab koob xaum rau kev siv ib zaug. Ntawm 5 koob txhaj Biomatikpen 2 ib leeg-siv nrog cartridges hauv ib pob.

Kev piav qhia ntawm daim ntawv tshuaj

Kev tshem tawm dawb. Thaum sawv ntsug, qhov ncua kev kawm ntawv tawm tsam, sib sau ua ib qho nag lossis daus. Cov supernatant yog qhov tseeb, tsis muaj xim lossis yuav luag tsis muaj xim. Cov nag lossis daus tau yooj yim resuspended nrog maj mam co. Kev rau txim rau s / c tswj hwm ntawm cov xim dawb, thaum sawv ntsug, qhov kev ncua tawm hauv tsev, sib sau ua ib qho dawb nag lossis daus. Cov supernatant yog qhov tseeb, tsis muaj xim lossis yuav luag tsis muaj xim. Cov nag lossis daus tau yooj yim resuspended nrog maj mam co.

Cov Tshuaj Pharmacokinetics

Kev Cuam Tshuam Kev ua kom tiav ntawm kev nqus thiab pib ntawm cov nyhuv ntawm cov tshuaj insulin nyob ntawm qhov chaw txhaj tshuaj (plab, ncej, pob tw), ntau npaum li cas (ntim ntawm cov tshuaj insulin), thiab cov tshuaj insulin nyob rau hauv kev npaj.

Kev faib Khoom faib Tawm hauv cov ntaub so ntswg tsis xwm yeem. Nws tsis hla tus cwj pwm ntawm lub cev thiab tsis nthuav tawm hauv cov mis niam. Metabolism Raug puas los ntawm insulinase feem ntau yog nyob hauv daim siab thiab ob lub raum.

Kev zam ua kom zoo nyob hauv zis - 30-80%.

Cov mob tshwj xeeb

Koj tuaj yeem siv tsis tau cov tshuaj Biosulin® N yog tias, tom qab tshee, qhov kev ncua tsis dhau vim yog dawb thiab tauv huab. Tawm tsam keeb kwm yav dhau los ntawm kev kho mob insulin, kev tshuaj xyuas cov ntshav qabzib ntau yog tsim nyog.

Ntxiv rau kev noj tshuaj insulin ntau dhau, ua rau cov ntshav qog ua rau ntshav qab zib tuaj yeem suav nrog kev hloov tshuaj, hla zaub mov, ntuav, raws plab, ua kom lub cev muaj zog ntau ntxiv, cov kab mob uas txo qis qhov xav tau ntawm insulin (kev mob siab rau lub siab thiab lub raum kev ua haujlwm, kev ua haujlwm ntawm adrenal cortex, pituitary lossis thyroid caj pas), hloov chaw txhaj tshuaj, thiab kuj cuam tshuam nrog lwm cov tshuaj.

Kev siv tshuaj tsis zoo los yog cuam tshuam hauv cov tshuaj insulin, tshwj xeeb tshaj yog nyob rau cov neeg mob uas muaj ntshav qab zib hom 1, tuaj yeem ua rau muaj mob hyperglycemia. Feem ntau, thawj cov tsos mob ntawm hyperglycemia pib maj mam dhau ob peb teev lossis hnub.

Cov no suav nrog kev nqhis dej, ntxiv tso zis, xeev ntuav, ntuav, kiv taub hau, liab thiab ntawm daim tawv nqaij, qhov ncauj qhuav, tsis qab los, tsis hnov tsw ntawm Acetone hauv cov pa ua pa. Yog tias tsis kho, hyperglycemia hauv ntshav qab zib hom 1 tuaj yeem ua rau muaj kev tiv thaiv cov mob ntshav qab zib ketoacidosis.

Cov koob tshuaj insulin yuav tsum raug kho rau kev ua haujlwm ntawm cov thyroid tsis zoo, Addison's disease, hypopituitarism, ua rau lub siab thiab / lossis lub raum tsis ua haujlwm, thiab ntshav qab zib mellitus hauv cov neeg laus dua 65 xyoo. Kev kho tshuaj ntawm cov tshuaj insulin kuj tseem xav tau yog tias tus neeg mob nce ntxiv ntawm kev ua haujlwm lub cev lossis hloov cov zaub mov li qub.

Cov kab mob tsis haum (tshwj xeeb yog kis tau tus mob) thiab cov mob uas kub taub hau nrog ua kom muaj cov insulin ntau ntxiv. Kev hloov pauv ntawm ib hom tshuaj insulin mus rau lwm qhov yuav tsum tau ua nyob ntawm kev tswjhwm ntawm cov ntshav nyob rau qib. Cov tshuaj txo qis cawv rau cov neeg haus cawv.

Vim tias muaj qhov ua rau nag lossis daus hauv qee qhov ntsuas, kev siv yeeb tshuaj hauv cov tshuaj insulin tsis pom zoo.

Qhov cuam tshuam rau kev muaj peev xwm tsav tsheb thiab tswj cov txheej txheem Thaum pib tswj hwm cov kua dej, hloov nws hom, lossis nrog lub cev lossis lub hlwb kev cuam tshuam loj ntawm lub cev, nws muaj peev xwm txo lub peev xwm tsav lub tsheb lossis tswj ntau cov txheej txheem, nrog rau koom nrog rau lwm yam kev phom sij uas yuav tsum tau nce mloog thiab ceev ntawm cov kev puas hlwb psychomotor Cov txheej txheem txhaj tshuaj thaum siv cov tshuaj insulin hauv daim cartridge nrog Carton Biosulin N yog tsim los rau kev siv nrog BiomatikPen koob txhaj tshuaj. Tus neeg mob yuav tsum tau txais kev ceeb toom txog qhov yuav tsum tau ua tib zoo ua raws li cov lus qhia hauv cov lus qhia rau kev siv tshuaj xau rau kev siv tshuaj insulin. Ua ntej siv, nco ntsoov tias tsis muaj kev puas tsuaj (piv txwv li, kab nrib pleb) rau ntawm daim cartridge nrog Biosulin® N. Tsis txhob siv lub taub hau ntawv yog tias pom muaj kev puas tsuaj. Tsis txhob siv Biosulin® N yog tias, thaum sib xyaw cov ntsiab lus ntawm lub taub ntim raws li cov lus qhia rau kev siv, lub insulin tsis ua kom dawb paug thiab dawb. Tsis txhob siv Biosulin N yog tias nws muaj plaub ya ri tom qab tov. Tsis txhob siv Biosulin N yog tias cov npliag dawb lo rau hauv qab lossis phab ntsa ntawm daim cartridge, tsim kom muaj "cov qauv khov". Tom qab daim cartridge tso rau hauv tus cwj mem syringe, ib txoj hlua xim yuav tsum pom ntawm lub qhov rai ntawm tus sau daim cartridge. Ua ntej muab daim cartridge tso rau hauv daim ntawv xwj, tig lub pob txha taub thiab nce siab kom lub khob pob txav ntawm qhov kawg mus rau qhov kawg ntawm daim cartridge. Qhov txheej txheem no yuav tsum tau ua dua tsawg kawg 10 zaug kom txog thaum txhua lub kua tau dawb thiab zoo li huab. Tom qab qhov no, ib qho kev txhaj tshuaj yog qhov tsim nyog. Yog tias tus cartridge twb nyob hauv lub tes tsho hauv tes, koj yuav tsum tig nws nrog lub taub ntim hauv sab hauv thiab nce tsawg kawg 10 zaug. Qhov txheej txheem no yuav tsum rov qab ua ntej txhua txoj kev txhaj tshuaj. Tom qab txhaj, koob yuav tsum nyob twj ywm hauv qab daim tawv nqaij tsawg kawg 6 vib nas this. Khaws lub pob nyem kom txog thaum lub koob raug tshem tawm hauv qab ntawm daim tawv nqaij, yog li ua kom ntseeg tau qhov kev tswj hwm kev noj tshuaj kom raug thiab cov ntshav lossis lymph nkag mus rau hauv rab koob lossis insulin cartridge yog txwv. Daim cartridge nrog cov tshuaj Biosulin N yog tsim rau cov tib neeg siv nkaus xwb thiab yuav tsum tsis txhob ua kom tiav. Cov txheej txheem kev txhaj tshuaj • Siv ob tug ntiv tes, khaws ib daim ntawm daim tawv nqaij, ntxig rab koob rau hauv lub hauv paus ntawm qhov quav ntawm kaum ntawm 45 °, thiab ntxig ntxig rau hauv qhov tawv nqaij. • Tom qab txhaj tshuaj, cov koob yuav tsum nyob twj ywm hauv qab daim tawv nqaij tsawg kawg yog 6 feeb kom ntseeg tau tias qhov tshuaj insulin nkag mus. • Yog tias cov ntshav pom ntawm qhov chaw txhaj tshuaj tom qab tshem tawm rab koob, maj mam nyem qhov chaw txhaj tshuaj nrog qhov qhwv qhov dej ntawm qhov dej uas muaj tshuaj tua kab mob (xws li dej cawv). • Nws yog ib qho tsim nyog yuav hloov chaw txhaj tshuaj.

insulin-isophan (tib neeg kev tsim kho tshuab) 100 IU Cov Khoom Taw Qhia: zinc oxide, sodium hydrogen phosphate, protamine sulfate, metacresol, crystalline phenol, glycerol, d / i dej.

Kev phiv tshuaj Biosulin N

Los ntawm ib sab ntawm cov metabolism: hypoglycemic tej yam kev mob (pallor ntawm daim tawv nqaij, nce tawm hws, palpitations, tshee tshee, tshaib plab, ntxhov siab, mob plab hnyuv hauv qhov ncauj, mob taub hau). Kev mob ntshav qog ntshav qis tuaj yeem ua rau txhim kho kev mob hypoglycemic coma. Kev ua xua: tsis tshua muaj - tawm pob ntawm daim tawv nqaij, Quincke's edema, qee qhov - anaphylactic ceeb. Cov tshuaj tiv thaiv hauv zos: hyperemia, o thiab khaus ntawm qhov chaw txhaj tshuaj, nrog rau siv sijhawm ntev - lipodystrophy ntawm thaj chaw txhaj tshuaj. Lwm yam: kab mob edema, qhov hloov pauv sai sai (feem ntau thaum pib kho).

Yeeb tshuaj sib cuam tshuam

Muaj ntau tus yeeb tshuaj uas cuam tshuam rau kev xav tau cov tshuaj insulin.

Cov nyhuv hypoglycemic ntawm insulin yog txhim kho los ntawm qhov ncauj hypoglycemic, MAO inhibitors, tsis xaiv-beta-blockers, ACE inhibitors, sulfanilamides, anabolic steroids, carbonic anhydrase inhibitors, bromocriptine, octreotide, tetracyclines, kefiloflindofilfindolfinfindolina, phenylinfininin, tshuaj ntsuab npaj muaj ethanol. Lub qhov ncauj hypoglycemic nyhuv ntawm insulin yog txo los ntawm qhov ncauj txwv, corticosteroids, cov thyroid hormones, thiazide diuretics, heparin, tricyclic antidepressants, sympathomimetics, danazole, clonidine, calcium channel blockers, diazoxide, morphine, phenytoin, nicotine.Hauv qab ntawm reserpine thiab salicylates, ob qho tib si ua kom tsis muaj zog thiab nce ntxiv hauv kev ua ntawm cov tshuaj muaj peev xwm ua tau

Cov nqi rau Biosulin N nyob hauv lwm lub nroog

Biosulin N hauv Moscow, Biosulin N hauv St. Petersburg, Biosulin N hauv Novosibirsk, Biosulin N hauv Yekaterinburg, Biosulin N hauv Nizhny Novgorod, Biosulin N hauv Kazan, Biosulin N hauv Chelyabinsk, Biosulin N hauv Omsk, Biosulin N hauv Samara, Biosulin N hauv Samara, Biosulin N hauv Rostov-on-Don, Biosulin N hauv Ufa, Biosulin N hauv Krasnoyarsk, Biosulin N hauv Perm, Biosulin N hauv Volgograd, Biosulin N hauv Voronezh, Biosulin N hauv Krasnodar, Biosulin N hauv Saratov, Biosulin N hauv Tyumen Kev xa khoom hauv Moscow

Thaum xaj nyob Apteka.RU, koj tuaj yeem xaiv xa mus rau lub tsev muag tshuaj yooj yim rau koj nyob ze koj lub tsev lossis txoj kev ua haujlwm.

Txhua qhov chaw xa khoom hauv Moscow - 696 chaw muag tshuaj

Hnub txheeb xyuas: Lub Plaub Hlis 2, 2016

Nyeem tag nrho kev tshuaj xyuas Rov xyuas los ntawm: Bondareva Margarita

Hnub txheeb xyuas: Lub Yim Hli 1, 2016

Hnub txheeb xyuas: Lub Yim Hli 19, 2016

Hnub txheeb xyuas: Cuaj hlis 15, 2016

Hnub txheeb xyuas: Lub Ob Hlis 18, 2017

Tib neeg kev sib xyaw ua ke cov tshuaj insulin Isofan: kev siv thiab tus nqi ntawm cov tshuaj

Isofan yog ib qho ua kom zoo siab rau kev tsim kho lub cev, uas yog siv los kho cov neeg mob ntshav qab zib.

Tib neeg cov tshuaj insulin, tau los ntawm kev tsim kho caj ces engineering siv siv cov thev naus laus zis DNA thev naus laus zis, suav tias yog tshuaj ncua sijhawm ntev.

Hauv cov khw muag tshuaj, nws tau muag hauv tsab ntawv ntawm kev ncua siv rau kev txhaj tshuaj uas txhaj rau hauv qab daim tawv nqaij. Tus nqi nyob ntawm qhov tsuas tshuaj, cov chaw tsim khoom thiab txawv ntawm 500 txog 1000 rubles.

Kws Tshuaj

Isofan - insulin, muaj cov nyhuv hypoglycemic. Nws yog nyob rau hauv kev sib cuag nrog cov xaus tshwj xeeb ntawm sab nraud cytoplasmic cell daim nyias nyias, vim li ntawm kev tau tsim cov tshuaj insulin. Nws pab txhawb kev ua haujlwm sai.

Vim tias qhov tseeb tias kev txav ntawm cov piam thaj hauv cov cell yuav nce, nws cov nyiaj hauv cov ntshav tsawg dua. Ib qho zoo sib xws yog ua tiav los ntawm kev txo tus nqi ntawm cov kua nplaum tsim los ntawm lub siab thiab nce nws nqus los ntawm cov ntaub so ntswg.

Cov tshuaj yeeb tshuaj ua rau lub sijhawm ntev vim yog kev nrawm ntawm kev nqus, uas cuam tshuam los ntawm ntau yam: insulin tau txhaj li cas (nws tuaj yeem raug txhaj rau hauv plab, ncej lossis pob tw), txoj kev tswj hwm, kev siv ntau npaum li cas.

Tom qab qhia txog soluble tib neeg cov roj ntsha tsim cov tshuaj insulin hauv qab daim tawv nqaij nrog kev txhaj tshuaj, nws ua kom tshwm sim tom qab ib thiab ib nrab teev. Cov tshuaj siv tau zoo tshaj los ntawm 4 rau 12 teev, yog ua haujlwm thaum nruab hnub.

Cov xwm txheej hauv qab no tuaj yeem raug ntaus nqi los ntawm cov yam ntxwv tseem ceeb ntawm Isofan: nws tsis mloog zoo hauv niam cov kua mis. Kev faib tawm hauv cov ntaub so ntswg yog tsis sib xws. Tsis txhob hla tawm lub tsho me nyuam. Txij li 30 txog 80% raug tso tawm los ntawm lub raum.

Cov lus qhia rau kev siv

Cov lus qhia rau kev siv qhia tseem ceeb ntawm hom kabmob uas siv tshuaj tua kab mob ntshav yog siv - insulin-tiv thaiv ntshav qab zib mellitus. Kev kho mob nyob rau hauv cov teeb meem no yog nqa tawm thoob plaws lub neej. Hauv qhov no, nws yog ib qho tseem ceeb kom ua raws li kev txhaj tshuaj qauv. Ntxiv rau, Isofan yog siv rau hom 1 thiab ntshav qab zib hom 2.

Tus kws kho mob tuaj yeem sau ntawv rau cov tshuaj yog tias tsis muaj qhov cuam tshuam los ntawm cov tshuaj uas muaj suab thaj txo qis. Tom qab ntawd cov tshuaj insulin yog tshuaj kho ua ke.

Qhov kev nce ntxiv ntawm cov ntshav qab zib kuj tseem tuaj yeem ua rau muaj kev mob tshwm sim, piv txwv, tom qab phais mob. Hauv qhov no, cov tshuaj insulin kuj tseem raug sau cia ua ib qho kev kho mob nyuaj. Nws yog tshuaj rau cov poj niam cev xeeb tub uas muaj ntshav qab zib.

Isofan tsuas yog siv rau hom 1 thiab ntshav qab zib hom 2!

Cov tshuaj yog contraindicated rau hauv cov neeg mob nws nquag muaj kev fab tshuaj thiab muaj ntshav qab zib tsawg.

Cov nyhuv txiav ua tiav

Cov kev phiv loj los ntawm kev noj Isofan yog:

Cov kev tsis zoo tshwm sim ntawm cov metabolism carbohydrate. Qhov no qhia hauv daim pallor ntawm daim tawv nqaij, tawm hws ntau dhau, lub plawv dhia ceev ceev, lub ntsej muag ntawm kev tshee, ib tus neeg xav noj tas li, muaj kev ntxhov siab ntxhov siab, nquag mob taub hau.
Kev ua xua qhia los ntawm daim tawv nqaij ua pob, Quincke's edema. Tsawg tsawg zaus, cov tshuaj ua rau anaphylactic kev poob siab.
Kev o tuaj yeem tshwm sim.
Tom qab txhaj tshuaj, khaus lossis o, ua pob tuaj. Yog tias kev kho mob ntev ntev, lipodystrophy yog tsim.

Hauv qhov no, thaum pib ntawm kev kho mob, kev kho tshuaj insulin tuaj yeem nqa tawm tsuas yog tom qab kev teem caij ntawm tus kws kho mob thiab nyob hauv kev saib xyuas nws.

Kev noj tshuaj ntau dhau

Nyob rau hauv cov ntaub ntawv ntawm kev qhia txog kev nce ntawm cov tshuaj, tus neeg mob yuav muaj cov cim qhia ntawm hypoglycemia. Hauv qhov no, koj yuav tsum noj ib qho piam thaj lossis cov zaub mov muaj txiaj ntsig nrog cov khoom noj (carbohydrates). Nws tuaj yeem yog cov ncuav qab zib, kua txiv hmab txiv ntoo, khoom qab zib.

Qhia ntau dhau heev ntawm Isofan tuaj yeem ua rau tsis nco qab. Nws raug nquahu kom koj txhaj tshuaj rau ntawm cov tshuaj 40% dextrose. Glucagon tuaj yeem muab tshuaj intramuscularly, leeg pob zeb lossis subcutaneously.

Kev tiv thaiv kev nyab xeeb

Thaum siv Isofan, nws yuav tsum tau yug los rau hauv lub siab tias yog tias koj txhaj tshuaj rau hauv tib qho chaw, lipodystrophy tuaj yeem tsim. Txhawm rau tiv thaiv, nws raug nquahu kom hloov thaj chaw txhaj tshuaj. Thaum ua kev kho cov tshuaj insulin, koj yuav tsum ua tib zoo saib xyuas koj cov piam thaj hauv ntshav.

Lub cuab yeej yuav tsum txhaj tshuaj nruj me ntsis raws li cov txheej txheem tau hais los ntawm kws kho mob. Txwv tsis pub, hypoglycemia yuav pib. Nws tuaj yeem tshwm sim vim kev siv cov khoom noj tsis txaus. Hauv qhov xwm txheej no, ib tus neeg muaj kev xav zoo li nqhis dej, qhov ncauj qhuav, tso zis heev, noj qab haus huv tsis txaus, qhia los ntawm xeev ntuav, ua rau ntuav, tsis qab los noj mov, ua pa tsw phem ntawm lub qhov ncauj los ntawm lub qhov ncauj.

Cov tshuaj siv yeeb yaj kiab yuav tsum tsis pub muaj lub cev txawv teb chaws, pob tshab, tsis muaj kev ziab hauv qab. Nws lub xub ntiag qhia tias muaj tshuaj lom lom ntawm insulin, yog li siv cov tshuaj yuav yog qhov txaus ntshai rau tus neeg mob.

Isophan yuav tsum nyob ntawm chav tsev txias thaum muab tshuaj. Nrog kev sib kis kab mob uas tau txais vim yog cov thyroid kawg, hypopituitarism, ntau npaum li cas ntawm cov tshuaj tau noj yuav tsum tau kho.

Isofan raug tshuaj los ntawm kws kho mob thaum tsis muaj kev cuam tshuam los ntawm kev kho mob nrog kev siv tshuaj qab zib.

Hla kev sib tshuam

Cov lus qhia rau kev siv yeeb tshuaj piav qhia txhua yam ntawm tus yam ntxwv ntawm cov tshuaj thiab nuances ntawm nws txoj kev siv.

Isofan human genetic engineering haj yam muaj zog yog tias siv cov tshuaj hauv qab no tib lub sijhawm:

Kev siv tshuaj hypoglycemic qhov ncauj.
MAO thiab ACE inhibitors, carbonic anhydrase.
Sulfonamides.
Anabolics.
Tetracyclines.
Cov tshuaj muaj tshuaj ethanol.

Cov txiaj ntsig ntawm Isofan txo qis thaum siv: qhov ncauj tawm tsam, tshuaj glucocorticoid, cov thyroid hormones, tshuaj tua kab mob, morphine. Yog tias nws tsis tuaj yeem thim cov tshuaj uas cuam tshuam rau kev ua haujlwm ntawm insulin, nws yog qhov yuav tsum ceeb toom rau tus kws kho mob uas tuaj koom txog qhov no.

Cov tshuaj zoo sib xws

Cov neeg mob ntshav qab zib txaus siab xav txog cov lus nug uas txhais tau li cas tuaj yeem hloov kho insulin. Nws raug nquahu kom siv cov analogues li ntawm Isofan rau kev kho mob: Humulin (NPH), Protafan-NM, Protafan-NM Penfill, Insumal, Actrafan.

Ua ntej hloov Isofan mus rau ib qho piv txwv, nws yog ib qhov tsim nyog yuav tsum sab laj nrog koj tus kws kho mob. Kev kho tshuaj Insulin yog ib qho kev kho mob hnyav. Nws yuav tsum muaj kev qhuab qhia ntawm ib feem ntawm tus neeg mob thiab kev soj ntsuam los ntawm tus kws kho mob.

Mob ntshav qab zib mellitus yog ib qho mob hnyav, uas, hmoov tsis, tsis tuaj yeem raug tshem tawm tag nrho. Raws li koj paub, tawm tsam cov nyom ntawm qhov mob, muaj qhov ua txhaum ntawm hormonal tso zis nyob rau hauv cov ntaub so ntswg ntawm lub txiav. Thiab feem ntau ntau, cov neeg mob tau sau tshuaj Isofan hluavtaws cov tshuaj insulin. Qhov tshuaj no tswj cov qib hauv qab zib hauv cov ntshav, ua kom lub luag haujlwm ntawm lub cev tag nrho.

Yog lawm, cov neeg mob xav paub txog cov ntaub ntawv ntxiv txog cov tshuaj. Qhov hluav taws xob ib nrab insulin Isofan cuam tshuam li cas rau lub cev? Cov lus qhia, contraindications, muaj teeb meem tshwm sim thaum txoj kev kho mob yog cov ntsiab lus tseem ceeb uas yuav tau xav hauv nqe lus.

Daim ntawv tso tawm

Nws tsis pub leejtwg paub tias cov ntshav qab zib yog ib qho uas txaus ntshai thiab txaus ntshai uas xav tau kev siv ntau yam tshuaj, suav nrog insulin.

"Isofan" yog lub npe lag luam ntawm cov tshuaj, uas yog npaj tau ua los ntawm cov tshuaj hormones semisynthetic. Ib cov tshuaj yog tsim hauv qhov kev daws teeb meem rau kev tswj hwm subcutaneous.

Cov tshuaj raug muag nyob rau hauv lub khob fwj ntawm 10 ml nrog tsuas tshuaj ntawm 40 IU / ml. Txhawm rau npaj qhov kev daws, dej ntxuav rau kev txhaj tshuaj yog siv.

Yog tias lwm cov tshuaj nrog tib yam muaj pes tsawg leeg thiab cov khoom ua haujlwm zoo li insulin Isofan. Cov lus ua nws yog "Insuman", "Protafan" thiab "Himulin". Nws yog ib qho tsim nyog hais tam sim ntawd hais tias cov tshuaj no tsuas yog xa tawm los ntawm cov tshuaj los yog lawv tawm los ntawm tus kws kho mob endocrinologist.

Cov tshuaj muaj cov khoom twg?

Isofan insulin yog ib yam tshuaj semi-hluavtaws uas muaj cov yam ntxwv zoo xws li cov khoom tsim los ntawm tib neeg cov txiav ua ke. Cov tshuaj txo cov ntshav qabzib hauv cov ntshav los ntawm kev txhim kho cov txheej txheem ntawm lipogenesis thiab gluconeogenesis.

Khoom cua ua hluav taws xob cuam tshuam nrog insulin-receptors ntawm lub cell week, ua kom cov txheej txheem kev zom zaub mov hauv cov cell. Tom qab noj cov tshuaj, muaj kev ua kom muaj zog ntawm qee cov enzymes, suav nrog glycogen synthetases, pyruvate kinases thiab hexokinases.

Cov nyhuv tuaj yeem pom ua tiav 1-1.5 teev tom qab kev qhia txog kev daws. Nyob ntawm qhov koob tshuaj thiab cov yam ntxwv ntawm tus neeg mob lub cev, kev ua haujlwm siab tshaj plaws ntawm cov hluavtaws insulin yog pom 4-12 teev tom qab kev tswj hwm. Cov nyhuv kav ntev li ntawm 11 txog 24 teev.

Lub cim tseem ceeb rau kev siv

Cov tshuaj "Insulin-Isofan" yog siv rau cov ntshav qab zib mellitus ntawm yam thib ob (daim ntawv insulin-nyob nrog). Nws kuj tseem siv rau kev kho mob insulin ib ntus. Qee zaum cov kev kho no kuj yuav tsum muaj ntshav qab zib hom 1. Piv txwv li, kev qhia txog kev daws teeb meem yog pom zoo rau cov neeg mob nyob rau hauv cov neeg mob thaum cov kua qab zib tsis ua rau cov nyhuv xav tau.

Kev qhia ntawm cov kua dej ntawm tib neeg yog qhov yuav tsum tau ua tom qab qee cov txheej txheem kev phais. Cov tshuaj no tseem siv rau kev mob ntshav qab zib hauv lub cev (cov mob ntshav qab zib ua rau tus poj niam lub cev xeeb tub). Kev qhia ntawm cov tshuaj insulin rau cov niam xeeb tub yog pom zoo yog tias kev noj zaub mov noj tsis muaj qhov ua rau xav tau.

Semi-hluavtaws insulin "Isofan": cov lus qhia rau kev siv

Muaj ntshav qab zib hom 2, cov neeg mob xav tau kev kho lub neej. Koob tshuaj, txhua hnub nyiaj, sijhawm tswj hwm - tag nrho cov no tau txiav txim siab los ntawm tus kws kho mob endocrinologist. Nws yog ib qho tseem ceeb kom nruj me ntsis ua raws txhua cov lus qhia ntawm tus kws tshaj lij. Muaj qee cov kev cai dav dav rau kev siv Insulin-Isofan.

Txoj kev daws teeb meem yog npaj tshwj xeeb rau kev tswj hwm subcutaneous. Muaj qee zaus, tus kws kho mob tuaj yeem pom zoo kom tswj cov tshuaj intramuscularly. Tso dej siab yog txwv.
Cov tshuaj tsis tuaj yeem siv nyob ntawm tib qho chaw.
Ua ntej koj yuav tsum co lub raj mis ob peb zaug, thiab tom qab ntawd kos lub qhov yuav tsum tau ntawm cov tshuaj tov rau hauv cov koob txhaj tshuaj (qhov koob tshuaj yog xaiv ib tus zuj zus).
Qhov kev txhaj tshuaj yuav tsum tau nqa tawm tam sim ntawd tom qab sau cov koob txhaj tshuaj.

Vials nrog kev daws tau muab tso rau hauv tub yees ntawm qhov txias ntawm 2-8 degrees Celsius. Ua ntej tswj cov tshuaj, koj yuav tsum ntsuas qhov theem ntawm cov piam thaj hauv cov ntshav. Txawm li cas los xij koj yuav tsum siv cov tshuaj yog tias koj pom tias muaj kev daws teeb meem huab, qhov tsim muaj ib qho nag lossis daus ntawm phab ntsa ntawm lub raj mis.

Puas muaj kev sib kis?

Cov tshuaj muaj qee qhov tsis sib haum - cov ntaub ntawv no muaj cov lus qhia rau kev siv. "Cov tshuaj Insulin-Isofan" tsis yog cov kws kho mob rau cov neeg mob hypoglycemia.

Cov tshuaj tiv thaiv tsis txaus suav nrog tshuaj insulinoma, nrog rau qhov ua kom siab txias rau hauv cov feem ntawm cov tshuaj.

Nws tsim nyog sau cia tias qee zaum txawm tias qhov hloov pauv ntawm qhov chaw txhaj tshuaj tuaj yeem ua rau muaj kev fab tshuaj thiab cov tshwm sim ntawm lwm cov kev mob tshwm sim.

Muaj kev phiv ntau

Cov tshuaj no yog tsim nyog rau cov neeg mob uas muaj cov tshuaj insulin-tiv thaiv ntshav qab zib. Txawm li cas los xij, kev kho mob cuam tshuam nrog qee qhov teeb meem. Kev yuam cai dab tsi tuaj yeem ua rau siv Isofan-Insulin? Cov kev qhia muaj cov ncauj lus hauv qab no:

Cov npe ntawm cov teeb meem tshwm sim feem ntau tuaj yeem suav nrog kev ua xua, uas nrog cov tsos mob ntawm pob khaus thiab urticaria, muaj ntshav nce siab ntau ntxiv, nce hauv lub cev kub thiab qhov pom ntawm edema.
Ib qhov xwm txheej txaus ntshai ntawm kev siv tshuaj insulin yog hypoglycemia, ib qho mob uas cuam tshuam los ntawm kev txo cov ntshav qab zib. Cov tsos mob muaj xws li pallor ntawm daim tawv nqaij, lub plawv dhia ceev ceev, ntxhov siab, pw tsaug zog tsis tu ncua, zoo li nqhis ntawm kev tshaib plab. Cov kev ua txhaum cai no feem ntau cuam tshuam nrog kev siv tshuaj tsis raug lossis tsis ua raws li kws kho mob cov lus qhia. Hauv cov xwm txheej hnyav tshaj plaws, ib qho kev mob hypoglycemic hnov qab.
Pib kev kho mob hauv qee cov neeg mob yog cuam tshuam nrog kev tsis pom kev. Nws tsis tsim nyog txhawj txog ntau qhov no, vim tias feem ntau cov kev mob tshwm sim no ploj mus ntawm lawv tus kheej.
Cov npe ntawm cov teeb meem tshwm sim suav nrog kev tiv thaiv tshuaj tiv thaiv kab mob, uas kuj dhau mus raws li lub cev yoog raws cov qauv tshuaj insulin no.
Thaum pib ntawm kev noj tshuaj, ua rau tawv nqaij muaj peev xwm ua tau, suav nrog liab thiab khaus. Lawv hla dhau lawv tus kheej li thiab.
Kev qhia ntawm kev siv tshuaj ntau dhau ntawm cov tshuaj yog fraught nrog kev puas siab puas ntsws. Nce npau taws, npau taws, hloov hauv tus cwj pwm, kev loj hlob ntawm kev nyuaj siab tau sau tseg.

Nws yog tsim nyog kom nkag siab tias Isofan insulin yuav tsum tau tswj hwm raws li lub sijhawm teem tseg los ntawm kws kho mob. Hla kev txhaj tshuaj yog nrog nws los ntawm kev loj hlob ntawm cov ntshav qab zib acidosis.

Hauv cov tshuaj niaj hnub, hluavtaws tib neeg insulins (raug luv luv thiab nruab nrab lub sij hawm), cov tshuaj tiv thaiv kab mob ntawm tib neeg, thiab kev sib xyaw yog siv los tswj cov piam thaj. Yog lawm, kev lag luam tshuaj muaj ntau cov tshuaj uas pab tshem tawm cov tsos mob ntshav qab zib ib ntus.

Rau daim ntawv teev cov kab mob analogues tuaj yeem suav cov tshuaj xws li "Actrafan", "Biogulin", "Diafan". Qee qhov xwm txheej, cov neeg mob raug pom zoo kom npaj rau "Protafan", "Humodar", "Pensulin". Cov insulin Bazal thiab Fereyn kuj pom zoo.

Nws yuav tsum nkag siab tias cov tshuaj hormones yog cov tshuaj hnyav, thiab koj tsis tuaj yeem siv lawv tus kheej rau hauv qee kis. Tsuas yog tus kws kho mob tuaj yeem xaiv qhov analog thiab txiav txim siab koob.

Piv txwv li, qhov tsawg kawg los ntawm ib qho kev ntxiv hauv kev daws teeb meem hauv qee cov neeg mob tuaj yeem ua rau muaj kev tsis haum tshuaj loj heev txog qhov tsis nco qab.

Lwm cov ntaub ntawv sib cuam tshuam txog yeeb tshuaj

Ua ntej pib txoj kev kho, koj yuav tsum qhia koj tus kws kho mob txog cov tshuaj uas koj siv. Kev txiav txim ntawm cov hluavtaws insulin yog ua kom zoo dua thaum noj nrog sulfonamides, hadrogens thiab anabolic steroids, MAO inhibitors, tsis siv tshuaj tiv thaiv tsis haum tshuaj.

Cov nyhuv hauv lub ntsej muag yog ntau tshaj tawm los tiv thaiv keeb kwm yav dhau los ntawm kev siv cov tshuaj Isofan nrog ketoconazole, cyclophosphamide, quinine, chloroquinine, quinidine, thiab cov tshuaj muaj lithium.

Los ntawm txoj kev, nws tsis pom zoo kom haus dej cawv thaum kho, txij li thaum ethanol txhim kho cov nyhuv ntawm cov tshuaj insulin.

Estrogens, tshuaj noj hauv qhov ncauj, glucagon, heparin, cov thyroid hormones tsis muaj zog cov nyhuv tshuaj. Tib yam tuaj yeem hais txog nicotine, tshuaj maj, morphine, qee qhov diuretics (tshwj xeeb, thiazide thiab lub voj), tricyclic antidepressants.

Nyob rau hauv txhua rooj plaub, nws yuav tsum nkag siab tias yog tias tsis muaj kev paub ntawm tus kws kho mob, koj tsis tuaj yeem hloov lub koob tshuaj lossis lub sijhawm ntawm insulin. Qhov tshwm sim ntawm kev txhawj xeeb tsis zoo thiab tsis zoo ntxiv yuav tsum tau qhia tam sim rau tus kws kho mob endocrinologist.

Isofan insulin: cov lus qhia rau kev siv thiab tus nqi ntawm cov tshuaj

Kev kho tshuaj Insulin muaj lub cim hloov, vim hais tias lub luag haujlwm tseem ceeb ntawm kev kho yog txhawm rau them nyiaj rau qhov ua tsis zoo ntawm cov khoom noj metabolism hauv carbohydrate los ntawm kev qhia cov tshuaj tshwj xeeb hauv qab tawv nqaij. Xws li cov tshuaj muaj feem cuam tshuam rau lub cev ib yam nkaus li lub cev insulin tsim tawm los ntawm lub txiav. Hauv qhov no, kev kho yog tag nrho lossis ib nrab.

Ntawm cov tshuaj siv rau ntshav qab zib, ib qho zoo tshaj plaws yog insulin Isofan. Cov tshuaj muaj cov tib neeg lub cev ua cov tshuaj insulin ntawm lub sijhawm ntev.

Cov cuab yeej muaj nyob hauv ntau hom. Nws raug tswj nyob rau hauv peb txoj kev - subcutaneously, intramuscularly thiab leeg. Qhov no tso cai rau tus neeg mob xaiv qhov kev xaiv zoo tshaj plaws rau kev tswj hwm theem ntawm glycemia.