Thioctic acid: kev tshuaj xyuas thiab contraindications, lus qhia rau kev siv

Thioctic acid: cov lus qhia rau kev siv thiab tshuaj xyuas

Lub npe Latin: Thioctic acid

ATX Code: A16AX01

Cov khoom xyaw nquag: Thioctic acid (Thioctic acid)

Cov tsim tawm: OZON, LLC (Russia)

Hloov kho cov lus piav qhia thiab yees duab: 10.24.2018

Cov nqi hauv khw muag tshuaj: los ntawm 337 rubles.

Thioctic acid yog tshuaj noj tshuaj metabolic.

Tso tawm daim ntawv thiab muaj pes tsawg leeg

Dosage daim ntawv ntawm thioctic acid:

• zaj duab xis-cov ntsiav tshuaj: puag ncig, biconvex, los ntawm daj mus rau daj-ntsuab, 600 mg ntsiav tshuaj muaj qhov pheej hmoo ntawm ib sab (10, 20 lossis 30 pieces hauv cov hlwv, hauv daim duab los qhia lub thawv 1, 2, 3, 4 , 5 lossis 10 blister ntim, 10, 20, 30, 40, 50 lossis 100 daim ib qho hauv cov kaus poom ntawm cov khoom siv polymer, hauv thawv ntawv thawv 1 tuaj yeem),
• mloog zoo rau qhov kev npaj ntawm kev daws rau kev lis ntshav: dej ntshiab daj-greenish kua nrog ib qho ntxhiab tsw (10 ml ib ampoule, 5 ampoules hauv qhov tawm hlwv lossis lub tais, hauv lub thawv ntawv cardboard 1 lossis 2 blister hlwb, lossis lub tais).

Composition 1 ntsiav tshuaj:

• cov tshuaj nquag: thioctic acid - 300 lossis 600 mg,
• Cov khoom siv pabcuam: microcrystalline cellulose, lactose monohydrate, croscarmellose sodium, povidone-K25, colloidal silicon dioxide, magnesium stearate,
• plhaub: hypromellose, hyprolose, macrogol-4000, titanium dioxide, zas xim quinoline daj.

Cov lus sib xyaw ntawm 1 ml ntawm mloog zoo rau kev npaj ntawm ib qho kev daws rau infusion:

• cov tshuaj nquag: thioctic acid - 30 mg,
• ntu ntu: ethylene diamine, propylene glycol, dej rau txhaj.

Cov Tshuaj Hauv Tshuaj

Thioctic lossis o-lipoic acid muaj peev xwm khi dawb radicals. Nws tsim nyob rau hauv lub cev tshwm sim thaum lub oxidative decarboxylation ntawm α-keto acids. Thioctic acid yog koom nrog oxidative decarboxylation ntawm pyruvic acid, nrog rau α-keto acids, ua coenzyme ntawm multienzyme mitochondrial complexes. Hauv nws cov nyhuv biochemical, nws yog ze rau ntawm cov vitamins B.

Cov tshuaj ua rau cov kev ua kom zoo rau cov leeg hlwb, txo cov concentration ntawm cov piam thaj hauv cov ntshav, nce glycogen ntau hauv lub siab, txo cov tshuaj insulin tsis kam, pab txhim kho daim siab ua haujlwm, thiab tseem koom nrog kev tswj hwm ntawm carbohydrate thiab lipid metabolism.

Cov Tshuaj Pharmacokinetics

Thaum muab tshuaj, thioctic acid yog nqus sai thiab ua tiav. Hauv 40-60 feeb, nws qhov siab tshaj plaws hauv lub cev tau ua tiav. Bioavailability yog 30%.

Tom qab iv kev tswj hwm ntawm cov tshuaj nyob rau hauv ib koob ntawm 600 mg rau 30 feeb, nws qhov siab tshaj plaws nyob rau hauv ntshav (20 μg / ml) tau tiav.

Cov metabolism ntawm cov tshuaj tshwm sim hauv daim siab, los ntawm oxidation ntawm sab saw thiab txuas. Cov tshuaj muaj cov nyhuv ntawm thawj kis los ntawm lub siab.

Nws yog tawm los ntawm ob lub raum (80-90%), ib nrab-lub neej yog 20-50 feeb. Qhov ntim ntawm kev faib tawm yog kwv yees li 450 m / kg. Tag nrho cov ntshav tshem tawm yog 10-15 ml / min.

Cov Yuav Tsum Tau Ua

• lactose intolerance, lactase deficiency, qabzib-galactose malabsorption (rau cov ntsiav tshuaj),
• cev xeeb tub thiab lactation,
• hnub nyoog txog 18 xyoo
• nce rhiab siab rau cov tshuaj ntawm cov tshuaj.

Ceev faj yuav tsum tau nqa tawm hauv / hauv kev qhia ntawm thioctic acid rau cov neeg laus dua 75 xyoo.

Cov lus qhia rau kev siv Thioctic acid: txoj kev thiab ntau npaum li cas

Cov tshuaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj yog npaum li cas nyob rau hauv nws tus kheej, tsis muaj zuaj los yog zom, 30 feeb ua ntej noj tshais, muaj dej ntau.

Qhov pom zoo koob tshuaj Thioctic acid yog 600 mg ib hnub ib zaug.

Txais tos ntawm cov ntsiav tshuaj daim ntawv ntawm cov tshuaj pib tom qab ib chav ntawm cov tswj hwm kav ntev 2-4 lub lis piam. Qhov siab tshaj plaws ntawm kev noj tshuaj yog 12 lub lis piam. Kev kho ntev dua yog ua tau raws li kws kho mob hais.

Mloog zoo rau kev daws rau infusion

Kev daws yog muab tshuaj rau dej maj mam maj mam.

Kev pom zoo koob tshuaj ntawm Thioctic acid yog 600 mg (2 ampoules) ib hnub.

Txoj kev hais daws: dilute cov ntsiab lus ntawm 2 ampoules hauv 250 ml ntawm 0.9% sodium chloride tov. Nws yog ib qho tsim nyog yuav tsum npaj daws qhov teeb meem tam sim ntawd ua ntej Txoj kev lis ntshav. Kev npaj npaj yuav tsum muaj kev tiv thaiv los ntawm lub teeb, hauv qhov xwm txheej nws tuaj yeem khaws cia li 6 teev.

Txoj kev daws teeb meem yog muab tshuaj rau dej ntws qeeb me me (tsawg kawg 30 feeb). Cov chav kawm ntawm kev thov ntawm cov tshuaj no yog 2-4 lub lis piam, tom qab ntawd koj yuav tsum mus rau ntawm cov ntsiav tshuaj ntawm Thioctic acid.

Sab sij huam

• GIT (mob plab zom mov): xeev siab, ntuav, raws plab, kub siab, mob plab,
• kev tiv thaiv kab mob: kev tawm tsam tsis haum (ua pob, khaus, urticaria), muaj kev tsis haum rau lub cev, nce mus rau anaphylactic ceeb,
• cov leeg hlwb: hloov pauv hauv saj,
• cov metabolism thiab khoom noj khoom haus: hypoglycemia (nws cov tsos mob: tawm hws, dias taub hau, mob taub hau, pom kev txawv).

Noj ntau dhau

Cov tsos mob ntawm kev tshaj tawm ntawm thioctic acid: xeev siab, ntuav, mob taub hau. Thaum noj ntawm 10 txog 40 g ntawm cov tshuaj, cov tsos mob nram qab no ntawm kev qaug cawv yog muaj peev xwm: kev txiav txim siab feem ntau qaug dab peg, tsis nco qab, tsis nco qab cov kua qaub, lub hauv paus tsis sib luag uas ua rau cov kab mob lactic acidosis, los ntshav ntau dhau los, mus txog rau qhov tuag, mob pob txha pob leeg mob necrosis, DIC, hemolysis , ntau yam hauv nruab nrog cev tsis ua haujlwm, tswj hlwb pob txha.

Tsis muaj ib qho tshuaj tua kab mob tshwj xeeb. Cov kev kho mob pom zoo. Yog tias muaj neeg muaj mob txaus noj, yuav tsum tau mus pw hauv tsev kho mob ceev. Kev Kho Mob: pais plab lav lav, kev nkag ntawm cov pa roj carbon activated, kev siv tshuaj tua kab mob, kho lub cev ua haujlwm tseem ceeb.

Cov lus qhia tshwj xeeb

Thaum kho nrog Thioctic acid, koj yuav tsum tsis txhob haus cawv.

Cov neeg mob ntshav qab zib yuav tsum muaj kev soj ntsuam tas li ntawm cov ntshav qabzib hauv cov ntshav, tshwj xeeb tshaj yog thaum pib ntawm txoj kev siv tshuaj. Txhawm rau kom tsis txhob mob hypoglycemia, yuav tsum tau txhaj tshuaj kho cov tshuaj insulin los yog qhov ncauj rau cov ntshav lub cev qhov muag ntshav. Thaum cov tsos mob ntawm tus mob hypoglycemia tshwm sim, thioctic acid yuav tsum tau txiav tawm tam sim ntawd.

Nws kuj tseem pom zoo kom tsum tsis txhob siv cov tshuaj ntawm cov tshuaj tiv thaiv kev mob siab, xws li khaus thiab malaise.

Yeeb tshuaj sib cuam tshuam

Lub sijhawm nruab nrab ntawm tsawg kawg 2 teev yuav tsum pom thaum noj thioctic acid nrog kev npaj muaj hlau, nrog rau cov khoom noj siv mis.

Clinically qhov tshuaj sib cuam tshuam ntawm thioctic acid nrog cov tshuaj / yeeb tshuaj hauv qab no:

• cisplatin: nws cov nyhuv txo,
• glucocorticosteroids: lawv cov nyhuv tshuaj tiv thaiv yog ua kom zoo dua,
• ethanol thiab nws cov metabolites: txo cov nyhuv ntawm thioctic acid,
• insulin thiab qhov ncauj hypoglycemic tus neeg sawv cev: lawv cov nyhuv ua tau zoo dua.

Qhov kub siab rau kev npaj daws teeb meem rau Txoj kev lis ntshav yog tsis sib haum nrog kev daws teeb meem ntawm dextrose (qabzib), fructose, Ringer, nrog rau cov kev daws teeb meem uas cuam tshuam nrog disulfide lossis SH-pawg.

Kev Xyuas Thioctic Acid

Kev tshuaj xyuas ntawm thioctic acid hauv lub network feem ntau zoo. Cov kws kho mob heev txaus siab rau nws cov khoom siv tshuaj uas yog cov tshuaj tiv thaiv neuroprotector thiab tshuaj tua kab mob antioxidant, thiab pom zoo kom siv cov neeg mob ntshav qab zib mellitus thiab polyneuropathies zoo. Ntau tus neeg mob, tshwj xeeb tshaj yog cov poj niam, siv tshuaj yaj yeeb rau qhov poob phaus, tab sis kev xav tau muab faib rau cov ntxim ntawm thioctic acid los txo qhov hnyav tshaj. Tus nqi siab ntawm cov tshuaj kuj tau sau tseg.

Dab tsi yog siv tshuaj yeeb?

Thioctacid lossis lipoic acid yog coenzyme ntawm oxidative decarboxylation ntawm pyruvic acid thiab ntau yam kua qaub alpha-keto. Cov khoom no koom nrog qhov feem ntau ntawm cov metabolism hauv feem ntau muaj tshwm sim hauv lub cev, nrog rau hauv cov metabolism hauv roj.

Cov tshuaj tau nthuav tawm nyob rau hauv daim ntawv ntawm hmoov ntawm lub teeb daj tint, muaj qhov iab tom qab. Nws yuav tsum raug sau tseg tias cov tshuaj tsis yaj hauv dej, tab sis tsuas yog hauv ethanol. Rau kev npaj tshuaj, ib daim ntawv soluble ntawm tej hmoov yog siv - trometamol ntsev.

Cov chaw muag tshuaj niaj hnub tsim cov thioctic acid npaj rau hauv daim ntawv ntawm cov ntsiav tshuaj thiab cov kev daws teeb meem (intramuscularly thiab intravenously).

Cov nom cov lus qhia rau kev siv tshuaj cais cov cim hauv qab no lub ntsiab kom noj thioctic acid:

• nrog rau kev txhim kho mob ntshav qab zib mellitus ntawm hom thib ob, thiab tseem muaj cov mob ntshav qab zib ua mob ntshav qab zib.
• cov neeg muaj suab polyneuropathy muaj cawv,
• hauv kev kho txoj kev kho mob rau txoj kev kho mob siab daim siab, cov no suav nrog kev ua haujlwm ntawm lub siab, kev ua kom lub cev rog ntawm cov kabmob, kab mob siab, nrog rau ntau yam tshuaj lom,
• kho hyperlipidemia.

Vim li cas lwm tus yog thioctic acid npaj siv? Txij li thaum cov tshuaj yog cov tshuaj tiv thaiv kab mob thiab muaj nyob hauv pawg pab pawg vitamin npaj, nws nquag siv los ua cov txheej txheem hauv lub cev zom zaub mov thiab ua kom yuag poob. Ntxiv rau, cov cuab yeej zoo li no tau nquag siv los ntawm cov kis las kom tshem tawm cov dawb radicals thiab txo qis ntawm oxidation tom qab kev qoj ib ce hauv chaw tawm dag zog.

Thioctic acid, uas rov txheeb xyuas tau, tuaj yeem ua kom nrawm dua thiab txhim kho cov leeg ua haujlwm ntawm lub cev, muaj cov txiaj ntsig zoo ntawm kev ua kom lub glycogen preservation.

Yog vim li ntawd, nws tau siv los siv roj ua rog.

Pharmacological kev txiav txim

Cov haujlwm tseem ceeb ntawm tib neeg lub cev yog qhov kev xav tsis thoob ntawm ntau cov txheej txheem uas pib los ntawm lub sijhawm ntawm kev xeeb menyuam thiab tsis nres rau kev sib cais thib ob hauv lub neej. Qee lub sij hawm lawv zoo li tsis tsim nyog. Piv txwv li, cov roj ntsha muaj sia - cov protein - yuav tsum muaj cov protein tsis muaj cov sib txuas, thiaj li hu ua cofactors, ua haujlwm kom raug. Nws yog rau cov ntsiab lus no uas lipoic acid, lossis, raws li nws tseem hu ua, thioctic acid, belongs. Nws yog ib qho tseem ceeb ntawm ntau lub enzymatic ntau txoj haujlwm ua haujlwm hauv tib neeg lub cev. Yog li, thaum cov piam thaj piam tag, cov khoom kawg yuav yog pyruvic acid ntsev - pyruvates. Nws yog lipoic acid uas koom rau hauv qhov kev ua kom muaj cov metabolism no. Hauv nws cov txiaj ntsig ntawm tib neeg lub cev, nws zoo ib yam li cov vitamins B - nws kuj koom nrog lipid thiab carbohydrate metabolism, nce glycogen cov ntsiab lus hauv daim siab ua ke thiab pab txo cov piam thaj hauv ntshav.

Vim nws lub peev xwm txhawm rau txhim kho cov roj metabolism hauv lub siab thiab lub siab ua haujlwm, lipoic acid txo cov kab mob pathogenic ntawm co toxins ntawm ob qho tib si endogenous thiab exogenous keeb kwm. Los ntawm txoj kev, cov tshuaj no yog cov tshuaj antioxidant, uas yog los ntawm nws lub peev xwm los khi dawb radicals.

Raws li kev tshawb fawb ntau yam, thioctic acid muaj cov kab mob siab hepatoprotective, hypolipidemic, hypocholesterolemic thiab hypoglycemic effects.

Cov tsim tawm ntawm cov tshuaj zoo li vitamin no tau siv hauv kev kho mob los muab tshuaj, nrog rau cov khoom siv ntawd, qee qib ntawm kev ua haujlwm biological. Thiab suav nrog ntawm lipoic acid nyob rau hauv kev daws teeb meem txo kev txhim kho lub peev xwm ntawm kev phiv tshuaj.

Cov ntaub ntawv muab tshuaj yog dab tsi?

Rau cov tshuaj "Lipoic acid", cov ntau npaum ntawm cov tshuaj yuav siv mus rau hauv tus kws kho qhov xav tau, nrog rau txoj kev xa mus rau lub cev. Yog li, cov tshuaj tuaj yeem raug yuav hauv cov chaw muag tshuaj hauv ob daim ntawv tshuaj - hauv daim ntawv ntawm cov ntsiav tshuaj thiab hauv daim ntawv ntawm kev daws nyob rau hauv kev txhaj tshuaj ampoules. Ua raws li cov tuam txhab kws tsim tshuaj no ua cov tshuaj, ntsiav tshuaj lossis tshuaj ntsiav tuaj yeem yuav nrog cov ntsiab lus ntawm 12.5 txog 600 mg ntawm cov tshuaj yeeb dej caw hauv 1 chav tsev. Cov ntsiav tshuaj muaj nyob rau hauv ib txheej tshwj xeeb, uas feem ntau muaj xim daj. Cov tshuaj hauv daim foos no tau ntim rau hauv cov hlwv thiab cov thawv ntawv cardboard uas muaj 10, 50 lossis 100 ntsiav tshuaj. Tab sis hauv ampoules, cov tshuaj muaj tsuas yog hauv daim ntawv ntawm 3% kev daws teeb meem. Thioctic acid kuj tseem yog cov tshuaj tiv thaiv ntau ntawm ntau yam tshuaj multicomponent thiab noj tshuaj pab rau lub cev.

Nyob rau kis twg kev siv yeeb tshuaj qhia?

Ib qho ntawm cov vitamin zoo li cov tshuaj tseem ceeb rau tib neeg lub cev yog lipoic acid. Cov lus qhia rau kev siv siv rau hauv nws txoj kev ua haujlwm thauj khoom raws li kev tso dej siab, tseem ceeb rau ntau yam txheej txheem. Yog li, lipoic acid, kev tsim txom thiab cov txiaj ntsig uas qee zaum ua rau kev tsis sib haum xeeb hauv kev sib tham hauv kev noj qab haus huv, muaj qee yam qhia tias siv rau kev kho kab mob lossis mob zoo li:

• mob plawv atherosclerosis,
• Kab mob siab kis (nrog daj)
• Kab mob siab hom mob nyob rau theem nquag,
• dyslipidemia - kev ua txhaum ntawm cov rog metabolism, uas suav nrog qhov hloov ntawm qhov feem ntawm lipids thiab ntshav lipoproteins,
• hepatic dystrophy (rog),
• intoxication nrog cov tshuaj, hlau hnyav, carbon, carbon, tetrachloride, nceb (suav nrog cov roj nplua nyeem),
• mob siab tsis ua hauj lwm
• mob caj dab ntev rau ntawm tus cawv tom qab,
• mob ntshav qab zib polyneuritis,
• cawv polyneuropathy,
• mob caj dab ntev
• hepatic cirrhosis.

Qhov chaw tseem ceeb ntawm kev ua haujlwm ntawm Lipoic Acid tshuaj yog kev kho rau kev quav dej caw, qaug tshuaj thiab qaug cawv, hauv kev kho kab mob siab, cov hlab ntsha hlwb, thiab ntshav qab zib mellitus. Tsis tas li, cov tshuaj no feem ntau siv rau hauv kev kho mob qog nqaij hlav nrog lub hom phiaj ntawm kev yooj yim ntawm chav kawm ntawm tus kabmob.

Puas muaj kev tiv thaiv tsis haum rau kev siv?

Thaum muab tshuaj kho, cov neeg mob feem ntau nug kws kho mob - lipoic acid rau dab tsi? Lo lus teb rau lo lus nug no tuaj yeem yog qhov ntev heev, vim tias thioctic acid yog cov neeg koom tes hauv cov txheej txheem ntawm tes tsom mus rau cov metabolism hauv ntau yam - lipids, roj cholesterol, glycogen. Nws koom tes hauv cov txheej txheem tiv thaiv tawm tsam dawb radicals thiab oxidation ntawm cov nqaij mos. Rau cov tshuaj "Lipoic acid", cov lus qhia rau kev siv qhia tsis tsuas yog cov teeb meem uas nws pab daws, tab sis kuj contraindications rau kev siv. Thiab lawv muaj raws li hauv qab no:

• kev tiv thaiv tsis haum
• keeb kwm kev fab tshuaj rau cov tshuaj,
• cev xeeb tub
• lub sijhawm uas pub niam mis rau menyuam noj.

Cov tshuaj no tsis tau sau nyob rau hauv kev kho mob ntawm cov menyuam yaus hnub nyoog qis dua 16 xyoo vim tias tsis muaj kev tshawb nrhiav hauv kev mob ntshav hauv lub cev no.

Puas muaj cov kev mob tshwm sim?

Ib qho ntawm cov roj ntsha biologically tseem ceeb ntawm qib cellular yog lipoic acid. Vim li cas nws xav tau hauv cov hlwb? Txhawm rau ua rau ntau cov tshuaj thiab hluav taws xob ua ntawm cov txheej txheem hauv kev zom zaub mov, ntxiv rau txo qis cov teebmeem ntawm oxidation. Tab sis txawm hais tias muaj txiaj ntsig zoo ntawm cov tshuaj no, noj tshuaj nrog thioctic acid yog tsis muaj kev xav, tsis yog rau lub hom phiaj ntawm tus kws tshaj lij, nws tsis tuaj yeem ua. Ntxiv rau, cov tshuaj no tuaj yeem ua rau cov kev mob tshwm sim hauv qab no:

• kev fab tshuaj tsis haum
• epigastric mob
• ntshav qab zib,
• zawv plab
• daim ntawv pov thawj (ob lub zeem muag),
• ua pa nyuaj
• kev tawm tsam ntawm daim tawv nqaij (ua pob thiab khaus, tso zis),
• los ntshav (vim muaj kev cuam tshuam cov teeb meem ntawm thrombocytosis),
• mob taub hau
• petechiae (pom taw los ntshav),
• nce siab intracranial,
• ntuav
• cramps
• xeev siab

Yuav noj tshuaj nrog thioctic acid li cas?

Txog rau cov tshuaj "Lipoic acid", cov lus qhia rau kev siv piav qhia txog lub hauv paus ntawm kev kho, nyob ntawm seb pib ntau npaum li cas ntawm ib pawg ntawm cov tshuaj. Cov ntsiav tshuaj tsis yog txhaws los yog zom, coj lawv sab hauv ib nrab ib teev ua ntej noj mov.Cov tshuaj tau xaj tau txog 3-4 zaug hauv ib hnub, qhov tseeb pes tsawg ntawm cov koob tshuaj thiab qhov tshwj xeeb ntau npaum li cas ntawm cov tshuaj tau txiav txim siab los ntawm tus kws kho mob tuaj koom ua raws li qhov xav tau ntawm kev kho. Qhov siab tshaj plaws niaj hnub tsuas pub noj tshuaj ntawm cov tshuaj yog 600 mg ntawm cov nquag tivthaiv.

Txog kev kho mob ntawm daim siab, lipoic acid npaj yuav tsum tau noj 4 zaug hauv ib hnub hauv qhov nyiaj ntawm 50 mg ntawm cov tshuaj nquag nyob rau ib zaug. Lub chav kawm ntawm kev kho mob yuav tsum yog 1 hlis. Nws tuaj yeem rov ua dua tom qab lub sijhawm qhia los ntawm tus kws kho mob koom nrog.

Tso dej siab tswj hwm ntawm cov tshuaj yog kws kho nyob rau hauv thawj lub lim tiam ntawm kev kho mob ntawm cov kab mob hauv cov mob hnyav thiab mob hnyav. Tom qab lub sijhawm no, tus neeg mob tuaj yeem hloov mus rau ib ntsiav tshuaj ntawm lipoic acid kho. Qhov tshuaj yuav tsum zoo ib yam rau txhua daim ntawv tshuaj - cov tshuaj txhaj muaj ntawm 300 mus rau 600 mg ntawm cov tshuaj nquag ib hnub.

Kev yuav ib cov tshuaj thiab yuav khaws nws li cas?

Raws li qhia hauv cov lus qhia rau kev siv tshuaj, lipoic acid nyob hauv lub tsev muag tshuaj yog muag los ntawm cov tshuaj. Nws siv tsis tau sab laj nrog cov kws kho mob tsis pom zoo, vim tias cov tshuaj muaj cov txheej txheem roj ntsha siab, nws siv nyob rau hauv txoj kev kho mob siab yuav tsum ua tib zoo xav txog lwm yam tshuaj uas tus neeg mob tau noj.

Cov tshuaj yuav hauv cov ntawv sau thiab ua ib qho kev daws teeb meem rau kev txhaj tshuaj yog muab cia rau hauv chav sov yam tsis muaj kev nkag mus thaum tshav ntuj.

Zoo dua los yog tsis zoo ua ke?

Qhov kev nquag nquag rau kev coj tus kheej yog rau cov tshuaj sib txawv, suav nrog cov tshuaj "Lipoic acid", nqe thiab tshuaj xyuas. Xav tias tsuas yog cov txiaj ntsig zoo tuaj yeem tau txais los ntawm ntuj zoo li cov tshuaj yeeb dej caw, ntau tus neeg mob tsis nco qab tias tseem muaj kev sib raug zoo ntawm pharmacological, uas yuav tsum tau coj mus rau hauv tus account. Piv txwv li, kev sib xyaw ua ke ntawm glucocorticosteroids thiab tshuaj nrog thioctic acid yog fraught nrog kev ua haujlwm ntawm adrenal cov tshuaj hormones, uas yuav ua rau muaj kev cuam tshuam ntau yam tsis zoo.

Txij li thaum lipoic acid nquag khi rau ntau yam tshuaj hauv lub cev, nws yuav tsum tsis txhob ua ke nrog kev siv cov tshuaj uas muaj cov khoom siv xws li magnesium, calcium, potassium, thiab hlau. Kev kho nrog cov tshuaj no yuav tsum tau muab faib sib txawv hauv lub sijhawm - so tsawg kawg 2-4 teev yuav yog qhov kev xaiv zoo tshaj plaws rau kev siv tshuaj kho mob.

Kev kho nrog cawv haus tinctures kuj tseem ua tau zoo cais tawm ntawm lipoic acid, txij li thaum ethanol tsis muaj zog nws cov haujlwm.

Puas yog nws poob ceeb thawj los ntawm kev noj thioctic acid?

Coob tus neeg ntseeg hais tias ib qho ntawm cov txiaj ntsig zoo thiab kev nyab xeeb txhais tau tias yuav tsum tau kho qhov hnyav thiab daim ntawv yog lipoic acid rau kev poob phaus. Yuav noj cov tshuaj no li cas kom tshem tau cov rog hauv lub cev? Qhov no tsis yog qhov teeb meem nyuaj, muab hais tias yam tsis muaj kev ua kom lub cev ua kom lub zog thiab hloov kho kev noj haus, tsis muaj tshuaj muaj peev xwm ua tiav txhua qhov kev poob phaus. Yog tias koj rov qab xav dua koj tus cwj pwm rau kev kawm lub cev thiab kev noj zaub mov kom zoo, ces kev pab lipoic acid hauv kev poob phaus yuav pom zoo heev. Koj tuaj yeem noj cov tshuaj hauv ntau txoj kev:

• Ib nrab teev ua ntej noj tshais lossis ib nrab teev tom qab nws,
• Ib nrab teev ua ntej noj hmo,
• tom qab ua si dhia ua si.

Tus cwj pwm no rau kev poob phaus koom nrog kev siv lipoic acid npaj nyob rau hauv ib qho nyiaj ntawm 25-50 mg rau ib hnub. Nws yuav pab cov metabolism hauv cov rog thiab cov suab thaj, nrog rau kev tshem tawm cov roj hauv lub cev uas tsis tsim nyog.

Kev zoo nkauj thiab thioctic acid

Ntau tus poj niam siv cov tshuaj "Lipoic acid" rau lub ntsej muag, uas yuav pab ua kom tawv nqaij kom huv, tshiab dua. Siv cov tshuaj thioctic acid tuaj yeem txhim kho qhov ua tau zoo ntawm lub khob tshuaj pleev ib ce los yog cov khoom noj kom qab zib. Piv txwv li, ob peb tee ntawm kev txhaj tshuaj uas tau ntxiv rau hauv qab zib lossis cov tshuaj pleev uas tus poj niam siv txhua hnub yuav ua rau nws muaj txiaj ntsig zoo dua los ntawm kev tawm tsam cov radicals, kev ua qias tuaj, thiab ua kom tawv nqaij ploj.

Nrog ntshav qab zib

Ib qho ntawm cov tshuaj tseem ceeb hauv thaj teb ntawm cov metabolism thiab metabolism hauv cov piam thaj, thiab, yog li ntawd, insulin, yog lipoic acid. Ntawm hom 1 thiab ntshav qab zib hom 2, cov tshuaj no pab kom tsis txhob muaj kev phom sij cuam tshuam nrog kev ua kom muaj zog, uas txhais tau tias rhuav tshem cov ntaub so ntswg. Cov kev tshawb fawb pom tau tias cov txheej txheem oxidative yog ua kom muaj txiaj ntsig zoo rau cov ntshav qab zib, thiab nws tsis muaj teeb meem dab tsi vim li cas xws li kev hloov pauv pathological. Lipoic acid ua raws li cov tshuaj antioxidant, uas tuaj yeem txo qis cov kev cuam tshuam ntawm kev puas ntsav ntawm cov ntshav qab zib ntawm cov nqaij. Kev tshawb nrhiav hauv thaj chaw no tau txuas ntxiv, thiab yog li cov tshuaj muaj thioctic acid rau ntshav qab zib yuav tsum tau noj tsuas yog kev pom zoo los ntawm cov kws kho mob koom nrog kev soj ntsuam cov ntshav thiab tus neeg mob lub luag haujlwm.

Lawv hais li cas txog cov tshuaj?

Ib feem ntawm ntau cov tshuaj nrog cov kev ua haujlwm lom neeg tseem ceeb yog lipoic acid. Cov kev mob thiab cov txiaj ntsig ntawm cov tshuaj no yog qhov ua rau muaj kev sib cav tsis tu ncua ntawm cov kws tshaj lij, ntawm cov neeg mob. Ntau tus neeg xav txog cov tshuaj no yog yav tom ntej ntawm cov tshuaj, uas nws pab nyob rau hauv kev kho mob ntawm ntau yam kab mob yuav ua pov thawj los ntawm kev xyaum. Tab sis ntau tus neeg xav hais tias cov tshuaj no tsuas muaj npe hu ua cov nyhuv tshuaj thiab tsis muaj lub luag haujlwm nrawm. Tab sis tseem, feem ntau ntawm kev tshuaj xyuas ntawm cov tshuaj "Lipoic acid" muaj qhov kev xav zoo thiab pom zoo. Cov neeg mob uas tau noj cov tshuaj no nrog ib chav kawm qhia tias tom qab kho lawv zoo dua, lub siab xav tshwm los ua lub neej zoo dua. Ntau tus nco ntsoov ib qho kev txhim kho hauv cov tsos - lub complexion ua huv, pob txuv ploj. Tsis tas li, cov neeg mob nco txog kev txhim kho tseem ceeb hauv kev suav cov ntshav - txo qis hauv cov piam thaj thiab cov cholesterol tom qab noj hom tshuaj no. Ntau tus hais tias lipoic acid feem ntau siv rau qhov poob phaus. Yuav ua li cas thiaj li nqa cov cuab yeej no kom poob phaus ntxiv yog qhov teeb meem tseem ceeb rau ntau tus neeg. Tab sis txhua tus neeg uas noj cov tshuaj kom poob phaus tau hais tias yuav tsis muaj tshwm sim yam tsis muaj kev hloov pauv kev noj haus thiab kev ua neej.

Cov tshuaj zoo sib xws

Cov roj ntsha tseem ceeb hauv tib neeg lub cev pab tiv thaiv ntau yam kab mob, nrog rau cov xwm txheej kab mob uas cuam tshuam rau kev noj qab haus huv. Piv txwv, lipoic acid. Cov kev mob tshwm sim thiab cov txiaj ntsig ntawm cov tshuaj, txawm hais tias lawv ua rau kev sib cav, tab sis tseem nyob hauv kev kho mob ntawm ntau yam kab mob, cov khoom no ua lub luag haujlwm tseem ceeb. Cov tshuaj nrog tib lub npe muaj ntau yam analogues, uas suav nrog lipoic acid. Piv txwv, Oktolipen, Espa-Lipon, Tiolepta, Berlition 300. Nws kuj tseem tuaj yeem pom nyob rau hauv cov kev hais daws multicomponent - "Niam ntawv - Ntshav Qab Zib", "Complivit Radiance."

Txhua tus neeg mob uas xav txhim kho lawv tus mob nrog rau kev noj tshuaj lossis tshuaj lom neeg lub cev, nrog rau kev npaj tshuaj lipoic acid, yuav tsum xub tham nrog tus kws tshaj lij txog kev muaj peev xwm ntawm kev kho mob, nrog rau kev tiv thaiv tsis raug mob.

Kev tshuaj xyuas ntawm cov kws khomob txog thioctic acid

Cov tshuaj yog qhov txaus siab nyob rau hauv cov nqe lus ntawm nws cov tshaj tawm antioxidant zog. Kuv siv cov phev hauv cov neeg mob nrog txiv neej ntxiv lawm tshob los tiv thaiv oxidative kev nyuaj siab, uas theorists tam sim no tau them ntau rau. Qhov taw qhia rau thioctic acid yog ib yam - mob ntshav qab zib polyneuropathy, tab sis cov lus qhia tau hais meej meej tias "qhov no tsis yog lub laj thawj rau kev txo qis qhov tseem ceeb ntawm thioctic acid hauv kev soj ntsuam."

Nrog kev siv ntev, nws tuaj yeem hloov pauv kev hnov ​​qab, txo qhov qab los noj mov, thrombocytopenia yog ua tau.

Kev loj hlob ntawm cov tshuaj antioxidant yog qhov tseem ceeb hauv tsev kho mob tau txais txiaj ntsig rau kev kho mob ntawm ntau yam kab mob ntawm tus kheej ntawm urogenital kheej.

Ib qho neuroprotector thoob ntiaj teb nrog cov khoom siv tiv thaiv kab mob antioxidant, siv tsis tu ncua los ntawm cov neeg mob ntshav qab zib mellitus, nrog rau cov neeg mob polyneuropathies, tau mob siab.

Tus nqi yuav tsum qis dua me ntsis.

Feem ntau, cov tshuaj zoo nrog cov khoom tiv thaiv kab mob antioxidant. Kuv pom zoo kom siv rau hauv kev soj ntsuam xyaum.

Kuv siv nyob rau hauv txoj hauv kev kho mob ntawm cov neeg mob uas mob ko taw mob ko taw, neuro-ischemic daim ntawv. Nrog rau kev siv tas li muab cov txiaj ntsig zoo.

Qee tus neeg mob tsis paub txog kev xav tau kev kho mob nrog cov tshuaj no.

Cov neeg mob ntshav qab zib yuav tsum tau txais yam tsawg kawg ntawm kev kho mob nrog cov tshuaj no ib xyoos ob zaug.

Zoo heev tiv thaiv thiab cuam tshuam nrawm thaum siv ntxuaj.

Cov tshuaj tsis ruaj khov, sai sai ua rau qaug zog ntawm lub teeb, yog li thaum ua haujlwm tawm ntawm cov leeg, nws yog qhov tsim nyog los qhwv lub raj mis daws hauv ntawv ci.

Lipoic acid (npaj ntawm thiogamma, thioctacid, berlition, octolipene) yog siv los tiv thaiv thiab kho cov mob ntshav qab zib mellitus, tshwj xeeb, kev mob ntshav qab zib polyneuropathy. Nrog rau lwm cov polyneuropathies (haus dej cawv, lom) tseem ua kom muaj cov nyhuv zoo.

Kev Ntsuam Xyuas Neeg Mob rau Thioctic Acid

Cov tshuaj no tau raug sau rau kuv kom txo tau lub cev qhov hnyav, lawv tau sau ntawv rau kuv ib koob tshuaj 300 mg 3 zaug ib hnub, rau peb lub hlis thaum kuv siv cov tshuaj no ua rau kuv daim tawv nqaij tsis zoo tag nrho, kuv hnub tseem ceeb ua rau nws yooj yim dua, kuv cov plaub hau tsum tsis poob, tab sis kuv lub cev hnyav tsis txav, thiab qhov no yog txawm hais tias ua tau raws li CBJU. Cov lus cog tseg kev hnyav ntawm cov metabolism, alas, tsis tshwm sim. Tsis tas li, thaum kev siv cov tshuaj no, cov zis muaj qhov tsis hnov ​​tsw kiag li, tsis hais ammonia, lossis nws tsis paub meej. Cov tshuaj poob siab.

Cov tshuaj antioxidant zoo heev. Pheej yig thiab zoo. Koj tuaj yeem siv sijhawm ntev heev tsis muaj qhov tshwm sim tsis zoo.

Kuv tau tshuaj thioctic acid thiab kuv tau noj 1 lub tshuaj 1 zaug ib hnub hauv 2 lub hlis. Kuv tau txais lub zog tom qab ntawm cov tshuaj no thiab kuv cov kev xav zoo li ploj mus.

Thioctic acid los yog lwm lub npe yog lipoic acid. Kuv tau coj 2 chav kawm ntawm kev kho mob nrog cov tshuaj no - thawj chav kawm ntawm 2 lub hlis nyob rau lub caij nplooj ntoo hlav, tom qab ntawd tom qab 2 lub hlis ib zaug ntxiv ob lub hlis ob chav. Tom qab thawj chav kawm, lub siab ntev ntawm lub cev pom tau zoo tuaj (piv txwv li, ua ntej qhov kev kawm kuv yuav ua tau li 10 zaum yws tsis muaj qhov ua tsis taus pa, tom qab 1 chav kawm nws twb tau 20-25). Qhov qab los noj mov kuj nce siab me ntsis thiab qhov tshwm sim, qhov hnyav tawm los ntawm 120 txog 110 kg hauv 3 lub hlis. Lub ntsej muag tau dhau los ua liab dawb, ashen ntxoov ntxoo ploj. Kuv haus 2 ntsiav tshuaj 4 zaug ib hnub nyob rau ib qho kev teem sijhawm li qub (txij thaum 8 teev sawv ntxov txhua 4 teev).

Cov lus qhia luv luv

Thioctic acid yog ib tus neeg pabcuam zom zaub mov uas ua rau tswj cov metabolism ntawm cov carbohydrates thiab cov rog. Cov lus qhia rau kev siv cov tshuaj no muab ib qho kev taw qhia - mob ntshav qab zib polyneuropathy. Txawm li cas los xij, qhov no tsis yog qhov ua rau tsis txaus ntseeg hais tias qhov tseem ceeb ntawm thioctic acid hauv kev xyaum siv. Qhov endogenous antioxidant muaj lub peev xwm zoo los khi qhov teeb meem dawb radicals. Thioctic acid siv sijhawm ua haujlwm ntawm cov metabolism hauv cellular, ua haujlwm ntawm coenzyme nyob rau hauv cov xov ntawm kev hloov pauv ntawm cov khoom siv tshuaj tiv thaiv kev tiv thaiv kab mob uas tiv thaiv lub cell los ntawm cov dawb radicals. Thioctic acid potentiates qhov kev ua ntawm insulin, uas cuam tshuam nrog kev ua kom cov txheej txheem ntawm kev siv cov kua nplaum nyob ntev.

Cov kab mob tshwm sim los ntawm endocrine-metabolic ntshawv siab tau nyob thaj tsam ntawm kev saib xyuas tshwj xeeb ntawm cov kws kho mob rau ntau tshaj ib puas xyoo. Thaum kawg ntawm 80s ntawm lub xyoo pua xeem, lub tswv yim ntawm "insulin resistance syndrome" tau qhia thawj zaug rau hauv cov tshuaj, uas ua ke, qhov tseeb, kev tawm tsam insulin, kev tsis txaus siab rau cov ntshav qabzib, nce ntawm cov "cholesterol" phem, txo qis cov roj "zoo", thiab rog dhau thiab hlab ntsha tawg. Cov tshuaj insulin kuj muaj qhov zoo sib xws "metabolic syndrome". Qhov tsis sib thooj, cov kws kho mob tau tsim kho cov pib ntawm kev siv tshuaj metabolic txoj kev tswj hwm los yog rov tsim lub cell, nws lub zog ntawm lub zog, uas yog ib qho mob rau kev ua haujlwm ntawm lub cev tag nrho. Kev kho cov roj ntsha muaj kev cuam tshuam nrog cov tshuaj hormone, tswj lub cev sib luag li ntawm chole- thiab ergocalciferol (pawg D vitamins), nrog rau kev kho nrog cov roj ntsha tseem ceeb, suav nrog alpha lipoic lossis thioctic. Hauv qhov no, nws yog qhov tsis ncaj ncees lawm los xav txog kev kho antioxidant nrog thioctic acid tsuas yog hauv cov ntsiab lus ntawm kev kho mob ntshav qab zib neuropathy.

Raws li koj tuaj yeem pom, cov tshuaj no kuj tseem yog qhov tseem ceeb ntawm kev hloov kho kev zom zaub mov. Thaum pib, thioctic acid tau hu ua "Vitamin N", hais txog nws qhov tseem ceeb rau cov leeg paj hlwb. Txawm li cas los xij, hauv nws cov qauv tshuaj, cov kab ke no tsis yog vitamin. Yog tias koj tsis delve rau hauv biochemical "hav zoov" nrog cov lus hais ntawm dehydrogenase complex thiab Krebs lub voj voog, nws yuav tsum raug sau tseg cov khoom siv antioxidant ntawm thioctic acid, nrog rau nws cov kev koom tes hauv kev rov ua dua ntawm lwm cov antioxidant, piv txwv li, vitamin E, coenzyme Q10 thiab glutathione. Ntxiv mus: thioctic acid yog qhov ua tau zoo ntawm txhua yam tshuaj tua kab mob antioxidant, thiab nws yog kev tu siab kom nco ntsoov txog qhov tsis muaj kev xav tsis zoo ntawm nws cov nqi kho thiab tsis muaj kev sib cais tsis txaus ntseeg ntawm kev taw qhia rau kev siv, uas muaj tsawg, raws li twb tau hais, ua rau mob ntshav qab zib neuropathy. Neuropathy yog qhov kev mob tsis zoo uas ua rau lub cev tsis txaus siab, ua rau muaj kev tsis sib haum xeeb ntawm cov hauv nruab nrab, cov leeg thiab cov khoom ntawm lub cev thiab qhov tsis txaus siab thiab cov desynchronization ntawm ntau yam plab hnyuv siab raum thiab tshuab. Txhua txoj hlab ntaws cuam tshuam, suav nrog thiab cov txais. Lub pathogenesis ntawm neuropathy yog ib txwm cuam tshuam nrog ob txoj kev: cuam tshuam lub zog metabolism thiab oxidative kev nyuaj siab. Muab cov "tropism" ntawm cov keeb kwm yav dhau los ua rau cov ntaub so ntswg mob, tus kws kho mob lub luag haujlwm tsis suav nrog paub meej txog cov tsos mob ntawm tus mob neuropathy, tab sis kuj tseem kho nrog thioctic acid. Txij li kev kho mob (theej, txawm tias tiv thaiv) ntawm neuropathy siv tau zoo txawm tias ua ntej pib ntawm cov tsos mob ntawm tus kab mob, nws yog ib qho tsim nyog yuav tsum pib noj thioctic acid sai li sai tau.

Thioctic acid muaj nyob rau hauv cov ntsiav tshuaj. Ib koob tshuaj ib zaug yog 600 mg. Muab cov synergy ntawm thioctic acid rau insulin, nrog kev siv tib lub sijhawm ntawm ob cov tshuaj no, qhov nce ntawm hypoglycemic ntxim ntawm insulin thiab ntsiav tshuaj hypoglycemic cov neeg sawv cev yuav raug sau tseg.