Captopril Sandoz yog ib qho angiotensin hloov mus rau enzyme inhibitor. Hauv lwm lo lus, cov tshuaj tiv thaiv hom thib ob ntawm angiotensin los ntawm hloov ua ntej. Yog li, qhov kev txo qis ntawm oligopeptide hormone ua rau kom cov ntshav khov tsis tseem ceeb. Nrog rau txoj cai ntau npaum, tus neeg mob normalizes tsis tsuas ntshav siab, tab sis kuj tag nrho peripheral vascular tsis kam. Cov nyhuv hypotensive ntawm cov tshuaj yog kiag li ywj siab ntawm kev ua si ntawm ntshav renin. Cov neeg mob ua rau lub siab poob qis dua nyob rau qhov tseem ceeb cov tshuaj hormones ntau. Nws muaj peev xwm txhim kho cov ntshav ncig los ntawm cov hlab ntshav ntawm myocardium. Raws li cov lus qhia rau kev siv, Captopril Sandoz txo cov platelet adhesion, muaj qhov cuam tshuam ntawm kev hloov kho ntawm lub plawv tsis ua hauj lwm, thiab tseem txo qis qis qhov nce hauv qhov ntim ntawm cov seem ventricle. Cov tshuaj yog nqus sai sai nrog lub plab zom mov. Cov ntsuas no yog tsawg kawg 75%. Cov neeg mob yuav tsum nco ntsoov tias kev noj haus ib txhij ntawm cov khoom noj thiab cov tshuaj txo cov nyhuv ntawm cov khoom tseem ceeb los ntawm yuav luag ib nrab. Qhov tseem ceeb ntawm cov tshuaj yog dhau los ntawm kev ua haujlwm zoo ntawm lub raum thiab tsuas yog ib feem me me ntawm nws tseem tsis hloov.

Captopril Sandoz tsuas yog kho los ntawm tus kws kho mob tshwj xeeb, tom qab dhau tag nrho cov kev ntsuas tsim nyog. Nws yog npaj rau cov neeg mob uas muaj qee yam kab mob hauv qab no: • mob ntshav siab, • kho cov ntshav siab, ua kom qhov mob me me ntawm lub raum rov qab los sis nws cov ceg, • kev cuam tshuam ntawm sab laug ventricle, uas cuam tshuam nrog yav dhau los myocardium, • mob raum vim raug tsim kuaj mob ntshav qab zib mellitus, • mob plawv tsis ua hauj lwm ntev. Nws yog ib qho tseem ceeb kom nco ntsoov tias cov tshuaj tau pom kev siv dav tsis yog siv tshuaj kho mob nkaus xwb, tab sis kuj yog ib feem ntawm txoj kev kho mob nyuaj. Cov neeg mob yuav tsum nkag siab tias yog tias koj tsis txuas rau qhov tseem ceeb rau koj kev noj qab haus huv, tom qab ntawd banal hypertension tuaj yeem ua rau muaj kev cuam tshuam loj heev. Retinal degeneration thiab nws cov ua haujlwm ua rau ib tus neeg ua tiav kev dig muag. Cerebral ncig yog qhov ua tsis tau mus tas li, lub siab ua haujlwm tsis zoo, uas ua kom muaj neeg tuag tsawg kawg yog tsib zaug. Kev nce siab hauv cov ntshav qab zib muaj kev cuam tshuam cov leeg hlwb, uas yuav nyuaj rau kev rov qab los. Lub raum puas tsuaj zuj zus txhua hnub nrog ntshav siab.

Cov lus sib xyaw thiab daim ntawv ntawm cov tshuaj

Cov khoom siv tseem ceeb ntawm Captopril Sandoz yog ib yam khoom ntawm tib lub npe. Cov tshuaj ntxiv hauv cov muaj pes tsawg leeg yog cov microcrystalline cellulose, cov hmoov txhuv nplej siab, lactose monohydrate, nrog rau cov kua qaub stearic. Ib qho khoom lag luam hauv German tsuas yog muaj nyob hauv daim ntawv ntsiav tshuaj ntawm lub tsev muag tshuaj. Ib qho twg muaj qhov ua puag ncig thiab du nto thiab, nyob ntawm qhov ntau npaum li cas, tuaj yeem nqa ib qho qauv zoo nkauj lossis plaub-nplooj. Cov ntsiav tshuaj yog pleev xim rau hauv cov xim daj dawb. Pom pom kev hnav tsoos tsho hauv qhov ntxoov ntxoo, tsis yog hauv txheej txheej sab saud, tabsis tseem nyob hauv seem. Ntawm ib sab, muaj kev pheej hmoo rau kev tawg yooj yim. Ib qho tshuaj tiv thaiv muaj nyob rau hauv qhov ntau npaum ntawm 6.25 mg, 12.5 mg, 25 mg, 50 mg thiab 100 mg. Xws li cov khoom siv ua rau nws yooj yim los kho cov tshuaj txhua hnub rau cov neeg mob. Txhua lub ntsiav tshuaj nyob hauv ib tus xovtooj ntawm contour uas ua los ntawm cov ntawv ci zaub mov. Txhua lub hlwv muaj kaum chav nyob. Kev ntim cov cardboard tuaj yeem suav ntawm ib txog kaum lub hlwb.

Cov Yuav Tsum Muaj

Ib qho yeeb tshuaj twg, tsis hais txog thaj chaw nws siv, tsis yog tsuas yog cov npe ntawm cov cim qhia, tab sis tseem kuaj mob uas txwv txoj kev kho mob. Cov lus qhia rau kev siv Captopril Sandoz tau hais tias cov tshuaj tsis raug tshuaj rau cov neeg mob uas muaj ntau tus kabmob: • tus kabmob tsis haum rau ib qho kev tivthaiv, nrog rau kev tiv thaiv tsis haum, • ntau yam kev ua xua, suav nrog kev mob hlwb, ua rau thaj chaw zoo nkauj ntawm daim tawv nqaij. , • cov ntsiab lus ntau ntxiv ntawm cov khoom lag luam nitrogenous nyob rau hauv cov ntshav, tawm hauv cov raum, • cov poov tshuaj ntau ntxiv hauv cov ntshav, • ib feem lossis ua tiav ntawm cov hlab ntsha hauv lub raum, qhov ncauj. Kuv muaj lub aorta, mitral valve los yog lub raum, • lub sijhawm rov qab los tom qab lub raum hloov pauv, • cov chaw kho mob uas tshwm sim los ntawm ntau dhau ntawm aldosterone ntau lawm, • muaj kev cuam tshuam rau cov ntshav tawm ntawm sab laug ventricle, • ntshav siab, • kev cuam tshuam ntawm myocardial infarction, uas ntau zaus nws yuav ua rau neeg tuag taus, • Kev siv cov tshuaj ib txhij nrog cov tshuaj raws aliskiren. Yog hais tias tus neeg mob tau muaj kev tsis txaus siab los ntawm cov npe saum toj no, tus kws kho mob sau ntawv muab tshuaj ib qho tsis pub poob.

Raws li cov kev tshawb fawb soj ntsuam thiab tshuaj xyuas ntau yam, Captopril Sandoz yuav tsum tau noj li ib teev ua ntej noj mov. Nws zoo dua tsis txhob zom cov ntsiav tshuaj thiab haus dej ntau. Qhov tsim nyog noj tshuaj rau qee kis tshwj xeeb yuav tsum tau tsim los ntawm cov kws kho mob los ntawm cov profile uas tsim nyog. Muaj ib qho kev kho mob zoo li qub tau qhia los ntawm cov neeg tsim khoom. Nws muaj kev nyab xeeb dua rau tus neeg mob los pib qhov pib nrog kev noj tshuaj 12,5 mg ib zaug. Kev txais tos yog kwv ob zaug ib hnub. Tom qab tus neeg mob noj thawj koob tshuaj, tus kws kho mob yuav tsum ua tib zoo saib xyuas tus mob hauv thawj teev. Yog tias tus neeg xav zoo zoo, nyob rau hauv cov ntaub ntawv no tsis muaj contraindications rau kev siv ntxiv. Txog kev kho mob kom zoo dua, tus kws kho mob thaum kho mob tuaj yeem kho qhov tshuaj txhua hnub nyob rau hauv ib qho kev coj thiab lwm yam. Rau cov neeg mob uas xav tau kev kho mob me me thiab txhawb nqa, nws yuav tsim nyog los noj 25 mg ib zaug. Qhov koob tshuaj txhua hnub hauv qhov no yuav tsum tsis pub tshaj 50 mg. Yog tias tsim nyog, tus kws kho mob nce txog li 150 mg, uas tau muab faib ua peb koob hauv ib hnub. Cov neeg mob uas muaj lub siab tsis ua haujlwm yuav tsum tau ua tib zoo saib xyuas thiab tsuas yog nyob hauv kev ntsia ntawm tus kws kho mob. Kev coj ua, nrog kev kuaj pom zoo sib xws, tus kws kho mob pom zoo kom pib kho nrog kev noj ntau npaum li 6.25 mg. Nrog rau qhov muaj zog zoo thiab qhov tsis muaj cov kev mob tshwm sim, cov koob tshuaj tuaj yeem hloov kho.

Sab sij huam

Ua ntej pib txoj kev kho nrog rau cov tshuaj, koj yuav tsum ua tib zoo paub koj tus kheej txog qhov tshwm sim tsis zoo uas tus neeg mob yuav ntsib. Yog lawm, Captopril Sandoz yog lub cim ntawm kev tsim kho tshiab thiab thev naus laus zis. Txawm li cas los xij, muaj qee qhov tshwm sim hauv qab no: • ib qho zuj zus ntawm neutrophils, leukocytes, platelets, eosinophils thiab qabzib cov ntsiab lus, • cov qog ntshav nce ntxiv, • cuam tshuam hauv kev ua haujlwm ntawm lub nruab zog, thaum koj tus kheej cov ntaub so ntswg pom tau tias yog txawv teb chaws thiab pib puas tsuaj los ntawm lub cev nws tus kheej, hauv cov ntshav, • ua txhaum tsis tsuas yog pw tsaug zog xwb, tab sis kuj tseem saj cov paj, nrog cov yastes yastaw, tsaug zog, kiv taub hau, poob siab, • hauv cov xwm txheej thoob plaws cov neeg mob yuav muaj kev tsis nco qab, tsaus muag, thiab mob nkees, • mob lub siab tawv, ua rau lub plawv dhia thiab ua pa ntev, nrog rau lub ntsej muag kub, lossis ua pa pawv, thiab hnoos qeev, • hnoos qhuav yam tsis hnoos zoo, mob ntsws, ua pa luv. , • tsis xis nyob hauv plab hauv daim ntawv ntawm xeev siab, thiab qhov hnyav, • ua txhaum cai ntawm lub tso quav ntau zaus, • qhov tshwm ntawm cov leeg me me rau ntawm cov leeg ntawm lub puab tsaig thiab tus nplaig. Yog tias tus neeg mob, tsis muaj kws paub txog ntawm tus kws kho mob, tau nce qhov koob tshuaj ntau dua txhua hnub, nws yog qhov yuav tsum tau nqa tawm cov kev mob plab uas yuav tsum tau ua kom sai li sai tau, muab tawm ib qho kev nqus thiab sau tshuaj txhawb kev kho mob.

Yeeb tshuaj sib cuam tshuam

Ua ntej koj yuav Captopril Sandoz, koj yuav tsum nkag siab tias cov tshuaj no tsis yog "phooj ywg" nrog txhua txoj hauv kev. Cov tshuaj no ua rau hauv chav kawm ntawm cov inhibitors tsis xav kom noj ib txhij nrog cov tshuaj uas cuam tshuam rau renin-angiotensin system hauv tib neeg lub cev. Nws yuav tsum nco ntsoov tias qhov kev nkag mus zoo li no tuaj yeem ua rau tus neeg mob txo qis ntshav siab thiab ua rau lub raum khiav tsis zoo. Kev pub nkag ib txhij yog kev tso cai, tab sis tsuas yog nyob rau hauv kev saib xyuas zoo los ntawm tus kws kho mob. Siv nrog aliskiren yog qhov pom zoo kom yuav zam tau los ntawm cov neeg mob kev mob raum, nrog rau hom ntshav qab zib hom 2. Kev sib xyaw nrog ntau yam poov tshuaj npaj yuav tsum zam. Xws li lub duet tuaj yeem ua rau qhov pom tshwm sim ntawm hyperkalemia. Yog tias qhov kev sib xyaw no tsis tuaj yeem zam, hauv qhov no tus neeg mob yuav tsum nyob hauv kev saib xyuas ntawm tus kws kho mob thoob plaws hauv chav kawm, ua ntu zus hla txhua qhov kev kuaj mob uas tsim nyog. Cov tshuaj Lithium-raws li tau khaws cia hauv lub cev, yog li ua kom cov tshuaj lom neeg cov tshuaj tseem ceeb hauv tib neeg cov ntshav.

Cov lus qhia tshwj xeeb

Captopril Sandoz yog ib qho yeeb tshuaj hnyav heev, uas yuav tsum tau txav mus kom ze nrog tib qho kev nco qab. Nws raug nquahu, ua ntej pib txoj haujlwm, los saib xyuas lub siab rau ob peb lub lis piam sib law liag kom nkag siab txog qhov txwv thiab qhov xwm txheej twg qee yam ntsuas pom. Daim duab zoo sib xws tseem ceeb heev hauv kev kho mob tom qab. Kev tivthaiv lub ntsiab tseem ceeb yuav ua rau cov ntaub ntawv tsis tseeb thaum tso zis mus rau acetone. Hauv qhov no, nws yog qhov tsim nyog ua ntej kom tsum tsis txhob noj thiab tsuas yog tom qab ob peb hnub rov qab ua qhov kev ntsuam xyuas. Rau tag nrho lub sijhawm ntawm kev kho mob kom zoo, tus neeg mob yuav tsum tso tseg txoj kev tsav tsheb, nrog rau ntau yam haujlwm uas yuav tsum muaj kev xav tshwj xeeb. Kev saib xyuas zoo kuj tsim nyog rau cov neeg mob uas tau txais kev tiv thaiv los ntawm cov kab mob sib kis ntawm cov ntaub so ntswg, nrog rau cov txheej txheem ntawm cov hlab ntshav ntawm cov hlab ntsha. Nrog rau txhua qhov tsos mob txaus ntshai, cov nyhuv ntawm cov tshuaj yuav tsum tau muab tso tseg sai li sai tau thiab cov zoo sib xws yuav tsum tau xaiv.

Tso cov ntaub ntawv thiab muaj pes tsawg leeg

Muaj nyob rau hauv cov ntsiav tshuaj, muaj cov cwj pwm hauv qab no:

cov duab yog kheej kheej los yog nyob hauv daim ntawv ntawm plaub-nplooj,
dawb xim
homogeneous nto
Qhov kev pheej hmoo yuav raug rau ntawm ib lossis ob sab.

Nws yog tsim nrog cov cov ntsiab lus sib txawv ntawm cov khoom siv tseem ceeb. Cov tso tawm, cov hnub so ntawm 6.25, 12.5, 100 mg, muaj cov duab puab puag ncig. Nyob rau hauv daim ntawv ntawm plaub nplooj plaub nplooj, daim ntawv uas muaj 50 thiab 25 mg ntawm lub tshuaj nquag tau tsim tawm.

Ntim hauv cov hlwv rau 10 ntau npaum. Lawv raug tso tawm rau hauv pob ntawv los ntawm cardboard. Cov kev qhia yog txuas.

Txhua qhov tso tawm muaj cov khoom xyaw uas nquag ua los ntawm captopril thiab cov khoom xyaw pabcuam. Cov tshuaj muaj pes tsawg leeg ntxiv:

pob kws nplej siab
lactose monohydrate,
microcrystalline cellulose,
stearic acid.

Tsis muaj cov tebchaw tsim kev puas tsuaj, muab cov nyhuv kho kom tsim nyog.

Captopril Sandoz

Captopril Sandoz: cov lus qhia rau kev siv thiab tshuaj xyuas

Lub npe Latin: Captopril Sandoz

ATX Code: C09AA01

Tus nquag siv: captopril (Captopril)

Cov tsim tawm: Salutas Pharma, GmbH (Salutas Pharma, GmbH) (Lub Teb Chaws Yelemees)

Qhia kho cov lus piav qhia thiab yees duab: 07/12/2019

Cov nqi hauv khw muag tshuaj: los ntawm 81 rubles.

Captopril Sandoz yog ib qho tshuaj tiv thaiv kab mob siab, tshuaj tua kabmob angiotensin hloov kho enzyme (ACE) inhibitor.

Pharmacological pawg

Arterial hypertension (mono- thiab ua ke nrog kev kho mob), congestive plawv tsis ua hauj lwm, cardiomyopathy, sab laug ventricular kawg nyob rau hauv ib qho kev mob nyob rau hauv cov neeg mob tom qab myocardial infarction, ntshav qab zib nephropathy nyob rau hauv cov neeg mob uas muaj hom 1 ntshav qab zib mellitus (nrog albuminuria ntau dua 30 mg / hnub).

Siv rau lub sijhawm qub

Rau cov neeg uas muaj hnub nyoog qeb tshaj txog 60-65 xyoo, cov chav kawm yuav tsum pib nrog kev noj ntau npaum li ntawm 6.25 mg ob zaug ib hnub. Tus nqi ntawm Captopril Sandoz yog 100 rubles. Koj tuaj yeem yuav cov tshuaj hauv peb lub khw muag tshuaj online nrog xa mus rau koj lub tsev lossis chaw ua haujlwm. Nws yog tso tawm raws li qhov kev nthuav qhia ntawm daim ntawv qhia.

Daim ntawv tso cai muab tshuaj LO-77-02-010329 ລົງ hnub Lub Rau Hli 18, 2019

Pharmacological kev txiav txim

Nws muaj cov cim suab hypotensive. Nws inhibits qhov sib txuas ntawm cov nquag angiotensin II vasoconstrictor los ntawm hemodynamically tsis muaj zog angiotensin I. Nws txo qis kev zais ntawm aldosterone.

Txhawb nqa kev tsub zuj zuj ntawm bradykinin, uas cuam tshuam cov synthesis ntawm vasodilating prostaglandins.

Nrog lub caij nyoog siv nws muaj cov nyhuv cardioprotective:

txo qhov uantej- thiab tomqab ntawd,
txhim kho cov ntshav txaus ntawm ischemic ib thaj chaw ntawm lub myocardium,
ua rau muaj kev pov hwm kev hauv plab,
ua kom qeeb siab rau qhov tsim ntawm hypertrophy, dilatation ntawm sab laug ventricle,
normalizes diastolic muaj nuj nqi.

Tsis ua rau mob reflex tachycardia. Txhawb lub cev hloov ntshav, txo cov platelet sib sau ua ke.

Tsim nyog cov koob tshuaj ntawm cov tshuaj rau lub plawv tsis ua rau tsis hloov ntshav siab. Pab txhawb rau kom muaj feeb ntau ntxiv, ua kom ib ce muaj zog.

Metabolically nruab nrab. Nws muaj cov poov tshuaj-sparing nyhuv. Cuam tshuam insulin rhiab heev.

Nws muaj cov nyhuv nephroprotective. Dilatation ntawm efferent raum ntsha pab txo qis intraglomerular siab. Nws inhibits intravascular proliferative tshua, normalizes tus qauv thiab kev khiav haujlwm ntawm epithelium.

Cov kev ua ntawm renin-angiotensin system qhia txoj kev txhim kho ntawm thawj qhov tshwm sim ntawm lub cev mus rau txoj kev noj tshuaj.

Tso tawm daim ntawv thiab muaj pes tsawg leeg

Cov tshuaj muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj: dawb, nrog lub ntsej muag zoo ib yam, puag ncig, ntau npaum li cas ntawm 6.25 mg - biconvex, ntau npaum ntawm 12.5 mg - convex ntawm ib sab tes, ntawm qhov tod tes, faib kev pheej hmoo, ntau npaum ntawm 25 thiab 50 mg - hauv daim ntawv ntawm plaub nplooj, nrog ib qho chamfer thiab tus ntoo khaub lig zoo li phom sij rau ob sab, ntau npaum ntawm 100 mg - ib sab yog convex, lwm qhov muaj qhov phom sij uas muaj tus ntoo khaub lig (10 hauv cov hlwv, hauv ib pob duab los ntawm 1, 2, 3, 4, 5 lossis 10 hlwv thiab cov lus qhia rau kev siv Captopril Sandoz).

1 ntsiav tshuaj muaj:

cov tshuaj nquag: captopril - 6.25, 12.5, 25, 50 lossis 100 mg,
Cov khoom siv pabcuam: lactose monohydrate, pob kws nplej, microcrystalline cellulose, stearic acid.

Chaw muag tshuaj

Cov tshuaj muaj cov kev lom neeg ncaj qha. Tsis cuam tshuam rau cov ntaub so ntswg-angiotensin. Cov nyhuv hemodynamic yog txuam nrog vasodilation, tsis nyob ntawm theem ntawm renin hauv cov ntshav.

Captopril Sandoz yog tus kws kho mob ua ib feem ntawm txoj kev kho mob ntshav siab.

Raug rho tawm sai sai. Qhov pib ntawm kev nqis tes yog sau tseg tom qab 30 feeb. Lub bioavailability ntawm cov tshuaj yog siab. Kev tswj hwm ntawm ncauj tau muab cov nyhuv siab tshaj plaws tom qab 1 teev. Lub sijhawm tiv thaiv yog ntawm 4 txog 12 teev.

Nws yog cov roj hauv lub siab, ua rau lub cev tsis muaj zog. Txaus siab los ntawm ob lub raum. Ib feem ntawm cov tshuaj txuas nrog yog hloov tawm ntawm lub cev. Nws tuaj yeem sau ntau zog thaum tsis ua haujlwm ntawm lub raum. Ib nrab-lub neej nyob rau hauv cov xwm txheej zoo li no nce mus rau ib thiab ib nrab hnub.

Cov Tshuaj Hauv Tshuaj

Captopril pab txo qis cov tshuaj angiotensin II los ntawm angiotensin I, uas txo cov kev tso tawm ntawm aldosterone. Qhov no ua rau txo qis ntshav siab thiab thauj ntawm lub plawv mob.

Raws li tshuaj ntawm cov yeeb tshuaj, cov ntshav ntws hauv lub plawv thiab lub raum txhaws ntxiv. Hauv cov neeg mob noj tshuaj ntau lub sijhawm ntev, myocardial ntshav txhim kho txhim kho.

Cov tshuaj txo cov kev pheej hmoo ntawm kev mob ntshav qab zib mob hlwb.

Dab tsi pab

Nws yog feem ntau kho raws li ib feem ntawm txoj kev kho mob ntawm cov kab mob hauv qab no:

ntshav siab
ntshav qab zib nephropathy,
mob plawv tsis ua hauj lwm,
mob vwm rau lub plawv vwm.

Raws li kev kho mob monotherapy tau zoo nyob rau ntawm thawj theem ntawm txoj hlab ntaws, kev taug ua yam tsis muaj teeb meem.

Contraindications

Contraindicated nyob rau hauv cev xeeb tub, pub niam mis. Siv tsis tau rau cov menyuam yaus hnub nyoog qis dua 18 xyoo.

Koj siv tsis tau cov tshuaj nrog:

keeb kwm ntawm tus kab mob angioedema uas yog ib qho keeb kwm twg,
ua kom sib xyaw tau rau cov tshuaj sib tov lossis lwm yam tshuaj ntawm pawg no,
ntshiab ntshav mob
thawj aldosteronism,
lactose intolerance, tsis muaj lactase hauv lub cev,
ob leeg lub raum leeg txoj hlab ntsha hlwb los yog leeg ntshav ntawm ib raum.

Tus neeg ua txhaum cai siv tsis tau tom qab hloov raum.

Captopril tsis siv rau cov menyuam yaus hnub nyoog qis dua 18 xyoo.

Nrog saib xyuas

Ceev faj yuav tsum tau siv rau cov kab mob hauv qab no:

hypertrophic obstructive cardiomyopathy,
mob ntshav qab zib
scleroderma, cov kab ke lupus erythematosus,
mitral valve stenosis, aortic orifice,
tshuaj hypovolemia
mob siab thiab lub raum tsis ua hauj lwm.

Thaum sau daim ntawv yuav tshuaj, nws yog ib qho tsim nyog yuav tsum tau coj mus rau hauv kev txiav txim siab siv cov ntsev uas tsis muaj zaub mov noj, cov khoom noj muaj txiaj ntsig zoo.

Kev muab tshuaj yog muab tib neeg. Nrog lub raum pathology, nws yog ib qhov tsim nyog los ua kom pom tseeb ntawm creatinine tshem tawm cov ntsuas. Hauv cov xwm txheej zoo li no, kev siv tshuaj tsawg kawg yog siv, ncua sijhawm ntev dua ntawm cov koob tshuaj.

Ntawm lub siab

Nws yog ib qho tsim nyog yuav tsum pib kho nrog qhov siv tshuaj tsawg kawg, tswj kev kam rau ua siab ntev ntawm thawj koob. Txib 12,5 mg ob zaug ib hnub. Kev noj tshuaj kom tsawg zuj zus yog pom zoo kom ua tiav qib theem. Cov neeg mob hauv cov pab pawg hnub nyoog laus tau sau tseg qhov tsawg kawg ntawm cov tshuaj.

Hauv kev mob plawv tsis ua haujlwm, ua ntej pib kev kho mob, tshuaj diuretics raug muab tso tseg lossis lawv cov koob tshuaj txo qis.

Nyob rau hauv tus nplaig lossis dej haus

Cov txheej txheem ntawm kev noj tshuaj yog txiav txim siab los ntawm qhov mob hnyav ntawm tus mob. Nrog kev npaj kho mob, cov tshuaj yuav tsum nqos tag nrho, ntxuav nrog dej kom txaus.

Thaum muaj teeb meem tshwm sim, kev tso cai rau kev kho mob raug tso cai.

Kev ua ntawm cov tshuaj tshwm sim sai sai, tom qab 30 feeb. Qhov txiaj ntsig zoo tshaj plaws nrog kev tswj hwm ntawm qhov ncauj yog pom thaum thawj teev.

Cov Tshuaj Pharmacokinetics

Kwv yees li 75% ntawm captopril yog nqus tau los ntawm txoj hnyuv hauv lub sijhawm luv luv. Tab sis thaum noj cov ntsiav tshuaj thiab zaub mov, qhov nqus tsawg dua li 30-40%. Qhov siab tshaj plaws ntawm cov tshuaj nquag hauv cov ntshav tau pom tom qab 0.5-1.5 teev tom qab noj cov tshuaj.

Cov tshuaj yaj yeeb nyob rau hauv lub siab. Ib nrab-lub neej yog tsawg dua 3 teev. Lub sijhawm no tau nce ntau ntxiv hauv cov neeg mob lub raum tsis ua haujlwm.

Dab tsi pab

Captopril yog siv rau kev mob ntshav txhaws. Ua ntej koj pib haus cov tshuaj, nws raug nquahu kom pom qhov ua rau muaj kev nce siab. Feem ntau tus mob no yog nrog los ntawm lwm yam kab mob, yog li koj yuav tsum tsis txhob noj tshuaj tus kheej. Cov tshuaj yuav tsum yog tus kws kho mob sau tseg. Kev siv cov tshuaj yog ua tau rau txhua theem ntawm kev kub siab.

Captopril ua ib feem ntawm txoj kev kho kom ncaj ncees yog kho rau lub plawv tsis ua kom muaj mob mus ntev. Cov tshuaj tau qhia rau sab laug ventricular kawg, uas tshwm sim los ntawm myocardial infarction. Hom 1 uas mob ntshav qab zib mob ntshav qab zib mob nephropathy kuj tau qhia kom noj cov tshuaj no.

Hematopoietic plab hnyuv siab raum

Kev siv lub sijhawm ntev ntawm cov tshuaj yog nrog los ntawm txoj kev loj hlob ntawm neutropenia, thrombocytopenia, thiab txo qis ntawm hemoglobin qib. Cov kev tsis zoo li no tshwm sim tsawg, dhau ntawm lawv tus kheej.

Kev siv ntev ntev ntawm cov tshuaj yog nrog los txo cov ntshav hauv hemoglobin. Cov kev tsis zoo li no tshwm sim tsawg, dhau ntawm lawv tus kheej.

Ntawm ib sab ntawm daim tawv nqaij

Kev noj cov tshuaj feem ntau nrog cov tawv nqaij khaus, qhov zoo li tawm pob. Lub sijhawm ntev ntawm kev siv cov tshuaj ua rau kev loj hlob ntawm lymphadenopathy. Tsawg dua yog pom dermatitis thiab urticaria.

Muaj kev pheej hmoo ntawm kev tsim Quincke edema. Cov tsos mob ntawm tus mob angioedema hauv cov leeg ntshav ua pa hem rau ob leeg txoj hlab pa. Cov tshuaj raug muab tso tseg, epinephrine muab tshuaj tam sim ntawd, thiab cov cua nkag tau ywj pheej.

Thaum noj captopril, koj yuav tsum zam qhov tsav tsheb.

Cov lus qhia tshwj xeeb

Ua txoj kev kho mob yuav tsum tau saib xyuas tsis tu ncua ntawm cov hemodynamic thiab lub raum kev ua haujlwm.

Nws yog ib qho tsim nyog yuav tsum coj mus rau hauv tus lej muaj peev xwm tsim muaj hypovolemia thaum siv ua ke nrog diuretics. Ib qho xwm txheej zoo li no cuam tshuam nrog kev mob taub hau vias, txawm tuag.

Txhawm rau zam txoj kev loj hlob ntawm cov teeb meem pab:

hloov kho koob
tshem tawm thawj zaug ntawm diuretics,
normalization ntawm hemodynamic tsis.

Cov hlab ntsha raum leeg yuav tsum them ib feem ntawm ib koob tshuaj, tshuaj xyuas lub xeev ntawm cov leeg tso zis.

Proteinuria thaum siv koob tshuaj ntau dua yog txo los yog ploj nws tus kheej.

Nws yog ib qho tsim nyog kom tsis txhob muaj kev sib txig sib luag ntawm cov tshuaj muaj cov poov tshuaj.

Ceev faj siv rau kev tiv thaiv cov nqaij mos pathology, siv tshuaj tiv thaiv kab mob. Nws yog ib qho tseem ceeb uas tswj cov ntsiab lus ntawm cov qe ntshav dawb thiab lwm cov qe ntshav.

Yuav tsum muaj kev soj ntsuam cov ntshav qabzib kom tsawg.

Kev txhim kho ntawm cholestatic jaundice, kev nce ntxiv ntawm lub titer ntawm hepatic transaminases yuav tsum tau tshem tawm cov tshuaj tam sim ntawd.

Kev kho nrog cov tshuaj tau nres ib hnub ua ntej pib kev npaj phais mob.

Thaum cev xeeb tub, captopril tuaj yeem siv tsis tau.

Cawv siv tau

Kev cuam tshuam nrog cov dej cawv ua kom muaj txiaj ntsig zoo rau cov tshuaj tiv thaiv, uas ua rau kev ua txhaum ntawm cov ntshav mus rau cov plab hnyuv siab raum thiab cov ntaub so ntswg. Zoo xws li cov xwm txheej hem txoj kev loj hlob ntawm cov mob vascular mob.

Kev siv dej cawv ua rau muaj txiaj ntsig ua kom sai ntawm kev tshem cov poov tshuaj tawm hauv lub cev, tshem tawm cov txiaj ntsig zoo ntawm cov tshuaj ntawm lub plawv mob.

Cawv txhawm rau txhim kho lub plab zom ntawm cov hlab ntsha, muaj lub cev tsis zoo. Tej zaum qhov kev txhim kho orthostatic vau.

Noj tshuaj ntau ntawm captopril sandoz

Kev noj tshuaj ntau dua ntawm cov tshuaj ua rau muaj kev mob hauv lub cev, ua rau muaj kev phom sij txog lub neej. Qhov kev txo qis hauv lub zog ua haujlwm ntawm lub plawv yog nrog los ntawm txoj haujlwm tsis txaus ntawm sab laug ventricle, poob rau hauv hemodynamics, thiab kev txhim kho ntawm lub xeev collaptoid. Cov tsos mob ntawm lub raum tsis ua haujlwm tshwm sim.

Cov xwm txheej no xav tau kev kho mob kub ceev. Nws yog ib qho tsim nyog yuav tsum tau yaug lub plab. Muab sorbents. Rov ntxiv cov roj ntshav, ua kev kho mob cov tsos mob.

Kev siv ntau yam nrog rau diuretics tuaj yeem ua rau kev loj hlob ntawm hypotension, txo qis ntshav poov tshuaj, thiab hypovolemia.

Cuam tshuam nrog lwm yam tshuaj

Kev siv ntau yam nrog rau diuretics tuaj yeem ua rau kev loj hlob ntawm hypotension, txo qis ntshav poov tshuaj, thiab hypovolemia.

Kev siv cov poov tshuaj npaj, cov zaub mov ntxiv yog cuam tshuam nrog kev txhim kho ntawm hyperkalemia thiab ua haujlwm cuam tshuam ntawm lub raum.

Kev mob siab rau ntshav yog tshwm sim los ntawm cov tshuaj uas siv rau cov tshuaj loog.

Nws yog tsis yooj yim sua kom sib txuas kev txais tos nrog Aliskiren thiab lwm yam ACE inhibitors.

Daim ntawv thov nrog Allopurinol ua rau pom kev ntawm neutropenia, nce qhov kev pheej hmoo ntawm kev tsis haum tshuaj loj.

Cov nyhuv hypotensive ntawm cov tshuaj yog txhim kho los ntawm beta-blockers, calcium antagonists, nitrates, tshuaj tsaug zog, tshuaj tiv thaiv kev npau taws.

Cov tshuaj tsub kom cov concentration ntawm digoxin hauv cov ntshav nce ntxiv.

Nws muaj kev pheej hmoo ntawm hypoglycemia thaum sib tham nrog cov kab mob hypoglycemic.

Kev ua kom qis qis dua ntawm kev tshem tawm cov roj ntsha lithium, nce ntxiv ntawm lawv cov ntshav tawm.

Thaum sib cuam tshuam nrog kub npaj, Cov nyhuv hypotensive yog kho dua.

Indomethacin, ibuprofen txo cov nyhuv ntawm cov tshuaj. Cov kev cuam tshuam zoo sib xws tau sau tseg nrog kev siv tshuaj estrogen, tshuaj tiv thaiv qhov ncauj, corticosteroids.

Siv nrog antacids thiab zaub mov txo lub bioavailability ntawm cov tshuaj los ntawm 40%.

Noj ntau dhau

Yog tias tus kws kho mob cov lus pom zoo tsis ua raws li, kev siv tshuaj ntau dhau ntawm Captopril yog ua tau, uas yog tus cwj pwm los ntawm cov tsos mob hauv qab no:

hais txo nyob rau hauv cov ntshav siab,
myocardial infarction,
cerebrovascular kev huam yuaj,
thromboembolism thiab nws qhov teebmeem.

Tus neeg mob xav tau kev kho mob.

Cov lus thiab cov xwm txheej ntawm kev cia

Cov tshuaj yeeb tshuaj no siv tau ob xyoos txij li hnub tso tawm. Daim hnub nyoog tuaj yeem nrhiav tau ntawm lub ntim tshuaj. Tab sis txhawm rau khaws cia cov tshuaj pharmacological ntawm cov tshuaj, nws yog ib qho tsim nyog yuav tsum tau muab cov khoom lag luam kom raug: chav tsev qhuav nrog cua kub tsis dhau +25 ° C.

Cov Cai Siv Tshuaj So

Nov yog daim ntawv yuav tshuaj.

Ib pob nrog 20 ntsiav tshuaj tus nqi txog 90 rubles.

Irina Zinovieva, hnub nyoog 57 xyoo, Novocherkassk: “Kuv tau mob ntshav siab ntev, yog li kuv tau sim siv tshuaj tiv thaiv kab mob ntau yam, kuv kuj paub nrog Katopril Sandoz. Cov tshuaj txo cov ntshav siab kom zoo, tab sis tsis zoo rau lub cev. Tom qab noj cov ntsiav tshuaj, kuv lub taub hau pib mob thiab zoo li kiv taub hau, thiab lub qhov ncauj qhuav. Nws yog qhov pheej yig, tab sis kuv tsis qhia kom txuag koj txoj kev noj qab haus huv. Kuv tsis pom zoo kom cov tshuaj rau leej twg. ”

Maria Kushnareva, 49 xyoo, Novosibirsk: “Ib zaug ntawm haujlwm, rau ib hlis muaj kev ua tiav. Tus siab tsis tu ncua ntxiv. Ib tug phooj ywg qhia hais tias kom noj Captopril. Kuv txoj kev noj qab haus huv zoo yuav luag sai sai tom qab noj tas. Tsis muaj kev phiv tshuaj, txawm hais tias ib tug phooj ywg ceeb toom tias tej zaum yuav tsaug zog lossis qee yam zoo li ntawd. Cov tshuaj yog pheej yig, thiab pab tau zoo dua li ntau cov tshuaj kim. Kuv pom zoo nws. "

Kev ntsuas rau siv

leeg ntshav siab
Renovascular tawg
mob plawv tsis ua hauj lwm - ua ib feem ntawm cov kev kho mob nyuaj,
Kev ua haujlwm ntawm sab laug ventricle nyob rau hauv qhov chaw kuaj mob ruaj khov tom qab myocardial infarction,
cov kab mob ntshav qab zib hauv cov neeg mob uas muaj hom 1 mob ntshav qab zib mellitus (nrog albuminuria ntau dua 30 mg / hnub).

Cev xeeb tub thiab lactation

Kev siv Captopril Sandoz yog contraindicated thaum yoj tes thiab lactation.

Thaum npaj kev cev xeeb tub, noj ACE inhibitors (suav nrog captopril) yuav tsum tsis ua ntxiv thiab hloov mus rau lwm txoj kev kho mob nrog kev tiv thaiv kev nyab xeeb nrog daim ntawv qhia txog kev nyab xeeb.

Yog tias muaj menyuam muaj tshwm sim nyob rau lub sijhawm kho, koj yuav tsum tsum tsis txhob noj Captopril Sandoz tam sim ntawd thiab xyuas kom tus neeg mob soj qab saib xyuas kev loj hlob ntawm tus menyuam hauv plab. Qhov no muaj feem nrog kev pheej hmoo ntau ntxiv ntawm kev txhim kho kev yug los ntawm plab me nyuam thaum siv cov tshuaj hauv thawj lub hlis thaum cev xeeb tub.

Cov poj niam ntawm lub hnub nyoog yug menyuam yuav tsum tau qhia txog qhov kev pheej hmoo siab ntawm kev kho nrog ACE inhibitors thaum cev xeeb tub cuam tshuam nrog tus kabmob thiab kev tuag ntawm tus menyuam thiab / lossis cov menyuam tshiab. Kev siv ntev ntev ntawm captopril hauv II thiab III trimesters muaj cov nyhuv ua rau lub plab hauv plab, ua rau oligohydramnios, lub raum tsis ua hauj lwm, thiab qeeb ossification ntawm cov pob txha pob txha taub hau. Hauv cov menyuam mos yug tshiab, nws tuaj yeem tshwm sim nws tus kheej rau tus mob neonatal lub raum tsis ua haujlwm, kev mob ntshav hauv lub plawv, hyperkalemia.

Hauv cov kua mis, muaj kwv yees li ntawm 1% ntawm koob tshuaj captopril tau pom.

Nrog lub raum tsis ua haujlwm

Kev siv Captopril Sandoz yog contraindicated nyob rau hauv kev mob raum loj, ob leeg lub raum mob hlab ntsha leeg los yog mob hlab ntsha ntawm ib lub raum nrog cov mob azotemia, hyperkalemia, azotemia, thiab ib qho mob tom qab hloov raum.

Ceev faj yuav tsum tau ua rau mob raum tsis ua haujlwm, ob tog txhav ntawm cov hlab ntsha raum, lossis stenosis ntawm ib lub raum leeg.

Captopril Sandoz kev txhaj tshuaj yog tsim los rau hauv tus account QC.

Kev tiv thaiv kev nyab xeeb

Txoj kev kho yog ua tiav los ntawm kev saib xyuas kev noj qab haus huv tas li. Ua ntej kho (1 lub lis piam), kev kho mob hypotensive dhau los yuav tsum tsis ua mus ntxiv. Hauv cov neeg mob uas muaj lub siab tsis ua haujlwm ntawm kev kub siab, qhov koob tshuaj yog maj mam nce txhua 24 teev kom txog thaum qhov siab tshaj plaws ua tiav nyob rau hauv kev tswj ntshav siab. Thaum kho, saib xyuas cov ntshav siab, saib xyuas cov ntshav muaj ntshav (ua ntej kev kho mob, hauv thawj 3-6 lub hlis ntawm kev kho thiab nyob rau ntu tom qab txog li 1 xyoos, tshwj xeeb tshaj yog rau cov neeg mob uas muaj kev pheej hmoo neutropenia), qib protein, ntshav poov tshuaj, urea nitrogen yog qhov tsim nyog , creatinine, lub raum ua haujlwm, lub cev nyhav, kev noj haus. Nrog rau kev txhim kho hyponatremia, lub cev qhuav dej, yuav tsum tau kho ntawm cov tshuaj ntau npaum li cas (koob tshuaj txo) yog qhov tsim nyog. Cov kab mob maculopapular lossis urticaric (tsawg dua ntais) tshwm sim thaum thawj 4 lub lis piam ntawm kev kho mob, ploj nrog qhov txo qis dua, ncua tshuaj, tsis siv tshuaj, thiab qhia cov tshuaj antihistamines. Kev noj tshuaj ntxiv neutropenia tsim muaj li 3 lub hlis tom qab pib kho (qhov tsawg tshaj plaws ntawm cov neeg leukocytes tau pom nyob hauv 10-30 hnub thiab mob siab ntev li 2 lub lis piam tom qab tsis siv tshuaj ntxiv). Kev hnoos (feem ntau pom tau hauv cov poj niam) tshwm sim ntau dua nyob rau thawj lub lim tiam (txij li 24 teev mus rau ntau lub hlis) ntawm kev kho, mob siab rau thaum kho, thiab nres ob peb hnub tom qab kawg ntawm kev kho. Kev ua txhaum ntawm saj thiab poob ceeb thawj yuav thim rov qab thiab rov qab los tom qab 2-3 lub hlis ntawm kev kho. Ceev faj yog yuav tsum tau ua thaum ua kev cuam tshuam kev phais mob (suav nrog kev kho hniav), tshwj xeeb tshaj yog thaum siv cov tshuaj loog dav dav uas muaj cov nyhuv hypotensive. Nrog kev txhim kho cholestatic jaundice thiab kev muaj mob ntawm lub siab tsis txaus ua lub siab tsis haum, kev kho mob yuav tsum tau tsum tsis ua ntxiv. Nws yog ib qho tsim nyog kom tsis txhob muaj cov hemodialysis los ntawm kev ua haujlwm siab ua los ntawm polyacrylonitrile metaallyl sulfate (piv txwv li AN69), hemofiltration lossis LDL-apheresis (anaphylaxis lossis anaphylactoid tshua yuav tshwm sim). Kev siv tshuaj kho kom lub qhov siab ua haujlwm zoo tuaj yeem ua rau muaj kev phiv tshuaj anaphylactic. Nws raug nquahu kom tsis suav txoj kev haus cawv thaum lub sijhawm kho. Siv nrog ceev faj thaum ua haujlwm rau cov tsav tsheb thiab cov neeg uas muaj kev cuam tshuam los ntawm kev saib xyuas ntau ntxiv.