Galvus analogues
Galvus (ntsiav tshuaj) Ntsuas: 208
Galvus yog ntsiav tshuaj npaj rau kev kho mob ntawm hom 2 mob ntshav qab zib mellitus raws li vildagliptin hauv ib koob tshuaj ntawm 50 mg. Nws tuaj yeem raug txiav txim siab ob qho tib si li monotherapy thiab ua ib feem ntawm kev sib xyaw ua ke thaum tsis muaj txiaj ntsig ntawm kev noj zaub mov zoo thiab tawm dag zog.
Cov tshuaj ntawm cov tshuaj Galvus
Cov analogue yog kim dua los ntawm 981 rubles.
Onglisa yog ib hom tshuaj siv tshuaj Asmeskas rau kev kho mob hom 2 mob ntshav qab zib mellitus raws li saxagliptin hauv tshuaj ntau npaum li 2.5 lossis 5 mg. Nws yog tshuaj ntxiv rau kev tawm dag zog lub cev thiab kev noj haus kom txhim kho glycemic tswj.
Cov analogue kim dua los ntawm 857 rubles.
Chaw tsim tshuaj paus: Beringer Ingelheim (Austria)
Cov Ntawv Tso Tawm:
- 5 mg ntsiav tshuaj, 30 pcs., Nqe los ntawm 1648 rubles
Cov lus qhia rau kev siv
Trazhenta - ib qho tshuaj Austrian npaj rau kev kho mob ntawm hom 2 mob ntshav qab zib mellitus, tuaj yeem raug tshuaj ob qho tib si li mono- thiab ua ib feem ntawm kev sib xyaw ua ke. Cov tshuaj tiv thaiv tsuas yog nyob rau hauv cov muaj pes tsawg leeg yog linagliptin hauv ib qhov tshuaj ntawm 5 mg. Trazenta tsis raug tshuaj rau ntshav qab zib hom 1, thaum cev xeeb tub, lactation, zoo ib yam li muaj rau menyuam yaus hnub nyoog qis dua 18 xyoo.
Cov analogue yog kim dua los ntawm 1418 rubles.
Chaw tsim tshuaj paus: Merck ntse thiab Dome (TEB CHAWS USA)
Cov Ntawv Tso Tawm:
- Ntsiav tshuaj 100 mg, 28 pcs., Nqe los ntawm 2209 rubles
Cov lus qhia rau kev siv
Januvia yog tshuaj yeeb tshuaj Asmeskas mob ntshav qab zib. Lub cev nquag ua haujlwm: sitagliptin (hauv daim ntawv ntawm phosphate monohydrate) 100 mg. Nws tuaj yeem siv los ua ntxiv rau kev tawm dag zog lub cev thiab kev noj haus kom tswj tau ntshav qab zib.
Cov analogue ntau kim dua los ntawm 182 rubles.
Chaw tsim tshuaj paus: Yog tau meej
Cov Ntawv Tso Tawm:
- Tab. 12,5 mg, 28 pcs., Nqe los ntawm 973 rubles
- Tab. 25 mg, 28 pcs., Nqe los ntawm 1282 rubles
Cov lus qhia rau kev siv
Vipidia yog tus neeg sawv cev hypoglycemic hauv ntsiav tshuaj nrog alogliptin. Muab kev txo qis hauv glycosylated hemoglobin thiab piam thaj. Nws yog qhia nyob rau hauv cov ntaub ntawv ntawm hom 2 mob ntshav qab zib mellitus nyob rau hauv daim ntawv ntawm monotherapy, zoo li nyob rau hauv kev sib txuas ua ke nrog kev kho mob nrog lwm tus neeg mob ntshav qab zib. Cov tshuaj noj zoo yog 25 mg / hnub, noj tsis hais zaub mov dab tsi. Contraindicated nyob rau hauv cov kab mob ntshav qab zib ketoacidosis, yam 1 mob ntshav qab zib mellitus, mob plawv heev rau lub plawv tsis ua hauj lwm, lub raum thiab lub siab ua haujlwm. Cov mob tshwm sim tuaj yeem suav cov mob taub hau, mob rau hauv epigastrium, tawm pob, ua mob rau kis ntawm ENT plab hnyuv siab raum. Cov menyuam yaus hnub nyoog qis dua 18 xyoo thiab poj niam cev xeeb tub tsis tau raug samfwm vim tias tsis muaj cov ntaub ntawv ntawm daim ntawv thov.
Analogs los ntawm qhov taw qhia thiab cov qauv ntawm kev siv
| Npe | Nqe hauv Lavxias | Nqe hauv Ukraine |
|---|---|---|
| Januvia sitagliptin | 1369 rub | 277 UAH |
| Onglisa saxagliptin | 1472 RUB | 48 UAH |
| Nesina alogliptin | -- | -- |
| Vipidia alogliptin | 350 rub | 1250 UAH |
| Trazhenta linagliptin | 89 rub | 1434 UAH |
Sib txawv muaj pes tsawg leeg, tuaj yeem ua ke nyob rau hauv kev taw qhia thiab cov qauv ntawm daim ntawv thov
| Npe | Nqe hauv Lavxias | Nqe hauv Ukraine |
|---|---|---|
| Avantomed rosiglitazone, metformin hydrochloride | -- | -- |
| Bagomet Metformin | -- | 30 UAH |
| Glucofage metformin | 12 RUB | 15 UAH |
| Globophage xr metformin | -- | 50 UAH |
| Reduxin Met Metformin, Sibutramine | 20 RUB | -- |
| Dianormet | -- | 19 UAH |
| Diaformin metformin | -- | 5 UAH |
| Metformin metformin | 13 RUB | 12 UAH |
| Tshuaj Metformin sandoz metformin | -- | 13 UAH |
| Siofor | 208 rub | 27 UAH |
| Formin metformin hydrochloride | -- | -- |
| Emnorm EP Metformin | -- | -- |
| Megifort Metformin | -- | 15 UAH |
| Tshuaj hlau Metformin | -- | 20 UAH |
| Tshuaj Metamin SR Metformin | -- | 20 UAH |
| Metfogamma metformin | 256 rub | 17 UAH |
| Tefor metformin | -- | -- |
| Glycometer | -- | -- |
| Glycomet SR | -- | -- |
| Tshuaj nyob | 37 RUB | -- |
| Metformin Canon metformin, ovidone K 90, pob kws hmoov txhuv, crospovidone, magnesium stearate, talc | 26 RUB | -- |
| Insuffor metformin hydrochloride | -- | 25 UAH |
| Metformin-teva metformin | 43 txhuam | 22 UAH |
| Diaformin SR metformin | -- | 18 UAH |
| Mepharmil Metformin | -- | 13 UAH |
| Metformin Yawg Liaj Ua Teb Metformin | -- | -- |
| Glibenclamide Glibenclamide | 30 RUB | 7 UAH |
| Maninyl Glibenclamide | 54 rub | 37 UAH |
| Glibenclamide-Health Glibenclamide | -- | 12 UAH |
| Glyurenorm glycidone | 94 rub | 43 UAH |
| Bisogamma Glyclazide | 91 rub | 182 UAH |
| Glidiab Glyclazide | 100 tshiav | 170 UAH |
| Lawj Xeeb MR | -- | 92 UAH |
| Kev kuaj mob mr Gliclazide | -- | 15 UAH |
| Glidia MV Gliclazide | -- | -- |
| Glykinorm Gliclazide | -- | -- |
| Gliclazide Gliclazide | 231 rub | 44 UAH |
| Glyclazide 30 MV-Indar Glyclazide | -- | -- |
| Glyclazide-Kev Noj Qab Haus Huv Gliclazide | -- | 36 UAH |
| Glioral Glyclazide | -- | -- |
| Kev kuaj mob Gliclazide | -- | 14 UAH |
| Diazide MV Gliclazide | -- | 46 UAH |
| Osliklid Gliclazide | -- | 68 UAH |
| Diadeon gliclazide | -- | -- |
| Glyclazide MV Gliclazide | 4 RUB | -- |
| Amaril | 27 RUB | 4 UAH |
| Glemaz glimepiride | -- | -- |
| Glian glimepiride | -- | 77 UAH |
| Glimepiride Glyride | -- | 149 UAH |
| Glimepiride diapiride | -- | 23 UAH |
| Thaj neeb | -- | 12 UAH |
| Glimax glimepiride | -- | 35 UAH |
| Glimepiride-Lugal glimepiride | -- | 69 UAH |
| Av nplaum glimepiride | -- | 66 UAH |
| Diabrex glimepiride | -- | 142 UAH |
| Meglimide glimepiride | -- | -- |
| Melpamide Glimepiride | -- | 84 UAH |
| Perinel glimepiride | -- | -- |
| Glempid | -- | -- |
| Raug Tsim | -- | -- |
| Glimepiride glimepiride | 27 RUB | 42 UAH |
| Glimepiride-teva glimepiride | -- | 57 UAH |
| Glimepiride Canon glimepiride | 50 RUB | -- |
| Glimepiride Pharmstandard glimepiride | -- | -- |
| Dimaril glimepiride | -- | 21 UAH |
| Glamepiride diamerid | 2 RUB | -- |
| Amaryl M Limepiride Micronized, Metformin Hydrochloride | 856 rub | 40 UAH |
| Glibomet glibenclamide, metformin | 257 rub | 101 UAH |
| Glucovans glibenclamide, metformin | 34 RUB | 8 UAH |
| Dianorm-m Glyclazide, Metformin | -- | 115 UAH |
| Dibizid-m glipizide, metformin | -- | 30 UAH |
| Douglimax glimepiride, metformin | -- | 44 UAH |
| Duotrol glibenclamide, metformin | -- | -- |
| Gluconorm | 45 rub | -- |
| Glibofor metformin hydrochloride, glibenclamide | -- | 16 UAH |
| Avandamet | -- | -- |
| Avandaglim | -- | -- |
| Janumet metformin, sitagliptin | 9 RUB | 1 UAH |
| Velmetia metformin, sitagliptin | 6026 rub | -- |
| Galvus Met vildagliptin, metformin | 259 RUB | 1195 UAH |
| Tripride glimepiride, metformin, pioglitazone | -- | 83 UAH |
| Comboglize XR metformin, saxagliptin | -- | 424 UAH |
| Comboglyz Prolong metformin, saxagliptin | 130 rub | -- |
| Gentadueto linagliptin, metformin | -- | -- |
| Vipdomet metformin, alogliptin | 55 RUB | 1750 UAH |
| Sinjardi empagliflozin, metformin hydrochloride | 240 rub | -- |
| Voglibose Oxide | -- | 21 UAH |
| Glutazone pioglitazone | -- | 66 UAH |
| Dropia Sanovel pioglitazone | -- | -- |
| Lixumia lixisenatide | -- | 2498 UAH |
| Guarem Guar cob | 9950 rub | 24 UAH |
| Insvada repaglinide | -- | -- |
| Novonorm Repaglinide | 30 RUB | 90 UAH |
| Cov Chaw Tshaj Tawm Repaglinide | -- | -- |
| Baeta Exenatide | 150 rub | 4600 UAH |
| Baeta Ntev Exenatide | 10248 rub | -- |
| Viktoza liraglutide | 8823 rub | 2900 UAH |
| Saxenda liraglutide | 1374 rub | 13773 UAH |
| Forksiga Dapagliflozin | -- | 18 UAH |
| Forsiga Dapagliflozin | 12 RUB | 3200 UAH |
| Invocana canagliflozin | 13 RUB | 3200 UAH |
| Jardins Empagliflozin | 222 RUB | 566 UAH |
| Trulicity Dulaglutide | 115 RUB | -- |
Yuav ua li cas thiaj nrhiav tau qhov pheej yig tshuaj ntawm cov tshuaj kim?
Txhawm rau kom pom qhov pheej yig cov khoom sib piv rau cov tshuaj, cov dav dav lossis cov lus sau, ua ntej txhua yam peb pom zoo kom them sai sai rau qhov muaj pes tsawg leeg, uas yog rau tib cov tshuaj nquag thiab qhia tau rau kev siv. Cov tshuaj sib xyaw zoo ib yam ntawm cov tshuaj yuav qhia tau tias cov tshuaj cuam tshuam nrog cov tshuaj, kws tshuaj sib npaug lossis chaw muag tshuaj. Txawm li cas los xij, tsis txhob hnov qab txog qhov ua tsis muaj zog ntawm cov tshuaj uas zoo sib xws, uas tuaj yeem cuam tshuam kev nyab xeeb thiab ua haujlwm. Tsis txhob hnov qab txog cov lus qhia ntawm cov kws kho mob, kev noj tshuaj rau nws tus kheej tuaj yeem tsim kev puas tsuaj rau koj kev noj qab haus huv, yog li nco ntsoov sab laj nrog koj tus kws kho mob ua ntej siv cov tshuaj.
Galvus kev qhia
Muaj pes tsawg leeg
1 tab. muaj cov vildagliptin 50 mg,
tus neeg muaj txiaj ntsig: MCC, anhydrous lactose, sodium carboxymethyl hmoov txhuv nplej siab, magnesium stearate,
Ntim
hauv ib pob ntawm 14, 28, 56, 84, 112 thiab 168 pcs.
Pharmacological kev txiav txim
GALVUS - vildagliptin - ib tus sawv cev ntawm chav kawm ntawm stimulators ntawm insular apparatus ntawm lub txiav, xaiv yam inhibits enzyme dipeptidyl peptidase-4 (DPP-4). Kev txwv sai thiab ua tiav ntawm DPP-4 kev ua haujlwm (> 90%) ua rau muaj kev nce ntxiv ntawm ob qho tib si hauv paus thiab zaub mov zais cia ntawm hom 1 glucagon-zoo li peptide (GLP-1) thiab glucose-tiv thaiv insulinotropic polypeptide (HIP) los ntawm cov hnyuv mus rau hauv cov kab ke rau txhua hnub.
Ua kom ntau ntxiv ntawm GLP-1 thiab HIP, vildagliptin ua rau muaj kev cuam tshuam ntau ntxiv ntawm kev txiav txim siab ntawm pancreatic? Cov cell rau cov piam thaj, uas ua rau muaj kev txhim kho hauv cov kua dej-insulin secretion. Thaum ua ntawv thov vildagliptin ntawm koob tshuaj 50-100 mg / hauv cov neeg mob uas muaj hom 2 mob ntshav qab zib mellitus, kev txhim kho hauv kev ua haujlwm ntawm pancreatic? Qib kev txhim kho ntawm?-Ua haujlwm ntawm lub zog yog nyob ntawm qib ntawm lawv qhov kev puas tsuaj thaum pib, yog li ntawm cov neeg tsis mob ntshav qab zib mellitus (nrog cov ntshav qabzib hauv qab), vildagliptin tsis txhawb cov tshuaj insulin secretion thiab tsis txo cov piam thaj.
Los ntawm kev nce qib ntawm cov endogenous GLP-1, vildagliptin tsub kom muaj kev cuam tshuam ntawm to-hlwb rau cov piam thaj, uas ua rau muaj kev txhim kho hauv cov kua nplaum-cov kev cai ntawm glucagon secretion. Kev txo qis hauv cov theem ntawm glucagon ntau dhau ntawm lub sijhawm noj mov, nyeg, ua rau muaj kev poob qis hauv insulin tsis kam.
Kev nce ntxiv ntawm cov insulin / glucagon piv rau cov keeb kwm ntawm hyperglycemia, vim tias qhov nce ntawm GLP-1 thiab HIP, ua rau cov ntshav qabzib ntau zuj zus los ntawm lub siab ob qho tib si nyob rau lub sijhawm prandial thiab tom qab noj mov, uas ua rau txo qis ntshav qabzib ntau ntau.
Tsis tas li ntawd, tawm tsam cov keeb kwm yav dhau los ntawm kev siv vildagliptin, qhov kev txo qis ntawm cov lipids hauv cov ntshav plasma raug sau tseg, txawm li cas los xij, cov nyhuv no tsis cuam tshuam nrog nws cov nyhuv ntawm GLP-1 lossis HIP thiab kev txhim kho ntawm kev ua haujlwm ntawm pancreatic?
Nws paub txog tias kev nce hauv GLP-1 tuaj yeem qeeb plab zom mov, tab sis cov nyhuv no tsis pom nrog kev siv vildagliptin.
Thaum siv vildagliptin nyob rau hauv 5795 cov neeg mob uas muaj ntshav qab zib hom 2 mellitus li 12 rau 52 lub limtiam li monotherapy lossis kev sib xyaw nrog metformin, sulfonylurea derivatives, thiazolidinedione, lossis insulin, qhov tseem ceeb ntev ntev txo qis nyob rau hauv cov concentration ntawm glycated hemoglobin (HbA1c) thiab kev ntshav sai yog qhov tseem ceeb.
Galvus, cim rau kev siv
Yam 2 Ntshav Qab Zib Hom:
- raws li monotherapy nyob rau hauv ua ke nrog kev noj haus txoj kev kho thiab qoj ib ce,
- ua ib feem ntawm ob qho kev sib xyaw ua ke nrog kev kho mob nrog metformin, sulfonylurea derivatives, thiazolidinedione lossis insulin thaum tsis muaj kev noj haus zoo rau kev noj zaub mov zoo, kev tawm dag zog thiab monotherapy nrog cov tshuaj no.
Cov Yuav Tsum Muaj
Kev tsis haum xeeb rau vildagliptin thiab lwm yam hauv Galvus,
cov menyuam yaus hnub nyoog qis dua 18 xyoo (qhov ua tau zoo thiab kev nyab xeeb tsis pom zoo).
Nrog saib xyuas:
kev ua txhaum loj ntawm daim siab, suav nrog cov neeg mob uas muaj kev ua haujlwm ntawm daim siab enzymes ntau dua (ALT lossis AST> 2,5 zaug siab dua qhov kev txwv siab tshaj ntawm ib txwm - 2.5 × VGN),
Mob raum los sis mob raum (nrog rau qhov kawg ntawm CRF ntawm hemodialysis) - kev paub txog kev siv yog tsawg, cov tshuaj tsis pom zoo rau pawg neeg no,
tsis tshua muaj cov kab mob tsis huv - galactose intolerance, lactase deficiency lossis malabsorption ntawm qabzib-galactose.
Tsuas tshuaj thiab tswj hwm
Galvus noj ntawm qhov ncauj, tsis hais txog ntawm kev ua zaub mov.
Cov tshuaj ntau npaum li cas ntawm cov tshuaj yuav tsum tau xaiv ib tus zuj zus nyob ntawm qhov siv tau thiab ua siab ntev.
Qhov pom zoo koob tshuaj ntawm cov tshuaj thaum monotherapy lossis ua ib feem ntawm ob qho kev sib xyaw ua ke nrog kev kho mob nrog metformin, thiazolidinedione lossis insulin yog 50 lossis 100 mg ib hnub ib zaug. Hauv cov neeg mob uas muaj mob ntshav qab zib hom 2 ntau dua uas tau txais kev kho mob insulin, Galvus pom zoo ntawm koob tshuaj 100 mg / hnub.
Ib koob tshuaj 50 mg / hnub yuav tsum yog 1 koob noj thaum sawv ntxov, ib koob tshuaj 100 mg / hnub - 50 mg 2 zaug hauv ib hnub thaum sawv ntxov thiab yav tsaus ntuj.
Cev xeeb tub thiab lactation
Hauv kev sim tshuaj, thaum kho nyob rau hauv cov koob tshuaj 200 zaug ntau dua li kev pom zoo, cov tshuaj tsis ua rau muaj qhov tsis taus thiab kev txhim kho thaum ntxov ntawm lub cev thiab tsis ua qhov cuam tshuam teratogenic rau tus me nyuam hauv plab. Tsis muaj cov ntaub ntawv txaus ntawm kev siv tshuaj Galvus hauv cov poj niam cev xeeb tub, thiab yog li ntawd cov tshuaj yuav tsum tsis txhob siv thaum cev xeeb tub. Thaum muaj teeb meem ntawm cov piam thaj hauv kev xeeb tub hauv cov poj niam cev xeeb tub, muaj qhov pheej hmoo ntawm kev muaj mob txha nqaj qaum, nrog rau cov zaus ntawm cov leeg tsis muaj hlwb thiab lub neej.
Txij li nws tsis paub meej tias vildagliptin nrog rau niam mis tso tawm rau hauv tib neeg, Galvus yuav tsum tsis txhob siv thaum lactation.
Sab sij huam
Thaum siv Galvus raws li kev kho mob monotherapy lossis hauv kev sib xyaw nrog lwm cov tshuaj, feem ntau cov kev phiv tshuaj yog mob me ntsis, ib ntus, thiab tsis tas yuav tsum tsis kho tawm. Tsis muaj qhov sib txheeb ze tau pom ntawm qhov tshwm sim tsis zoo (AE) thiab hnub nyoog, poj niam txiv neej, haiv neeg, sijhawm siv, lossis noj tshuaj ntxiv. Qhov tshwm sim ntawm angioneurotic edema thaum kho nrog Galvus yog ≥1 / 10,000. Tawm tsam keeb kwm ntawm kev kho mob nrog Galvus, kev ua haujlwm ntawm daim siab (suav nrog rau daim siab mob siab) thiab cov chav kawm asymptomatic tsis tshua pom. Feem ntau, cov kev ua txhaum thiab kev hloov pauv ntawm daim siab ua haujlwm los ntawm cov cai los daws teeb meem ntawm nws tus kheej yam tsis muaj teeb meem tom qab tsis txiav kev kho mob. Thaum siv cov tshuaj Galvus hauv koob tshuaj 50 mg 1 lossis 2 zaug hauv ib hnub, qhov ntau zaus ntawm kev nce siab hauv kev ua haujlwm ntawm daim siab daim siab (ALT lossis AST ≥3 × VGN) yog 0.2 lossis 0.3%, ntsig txog (piv nrog 0.2% hauv pawg tswj) Cov. Kev nce ntxiv ntawm kev ua haujlwm ntawm daim siab enzymes hauv feem ntau yog asymptomatic, tsis tau nce zuj zus, thiab tsis yog nrog cov kev hloov pauv ntawm cholestatic lossis nqaij tawv.
Cov lus qhia tshwj xeeb
Muaj qee zaus, thaum ua ntawv thov vildagliptin, qhov kev nce ntawm aminotransferases raug sau tseg (feem ntau tsis muaj kev kuaj mob pom). Ua ntej sau tshuaj thiab thaum thawj xyoo ntawm kev kho mob (1 zaug hauv 3 lub hlis), nws raug nquahu kom txiav txim siab cov kab mob biochemical ntawm lub siab ua haujlwm. Nrog rau qhov kev nce ntawm aminotransferases, qhov tshwm sim yuav tsum paub tseeb los ntawm kev tshawb nrhiav dua, thiab tom qab ntawd ua ntu zus txiav txim siab cov biochemical tsis ua haujlwm ntawm daim siab ua haujlwm kom txog thaum lawv ua haujlwm. Yog tias kev ua haujlwm ntau dhau ntawm AST lossis ALT yog 3 zaug siab dua qhov kev txwv sab sauv ntawm kev suav yog paub tseeb los ntawm kev tshawb nrhiav zaum ob, pom zoo kom thim cov tshuaj. Nrog rau kev txhim kho jaundice lossis lwm cov cim ntawm lub siab ua haujlwm tsis zoo, cov tshuaj yuav tsum tau nres tam sim ntawd thiab tsis rov pib dua tom qab ua haujlwm ntawm daim siab ua haujlwm. Yog tias xav tau cov tshuaj insulin, vildagliptin tsuas yog siv ua ke nrog cov tshuaj insulin. Cov tshuaj yuav tsum tsis txhob siv rau hom 1 mob ntshav qab zib mellitus lossis rau kev kho mob ntshav qab zib ketoacidosis. Nyob rau lub sijhawm kho mob (nrog kev loj hlob ntawm kiv taub hau), nws yog ib qho tsim nyog yuav tsum tsis txhob tsav tsheb thiab koom nrog cov kev phom sij uas yuav tsum tau muaj kev xav ntau ntxiv thiab ceev ntawm cov kev tiv thaiv psychomotor.
Yeeb tshuaj sib cuam tshuam
Galvus muaj qhov pheej hmoo tsawg rau kev sib txuam tshuaj. Txij li Galvus tsis yog cov keeb ntawm cytochrome P450 enzymes, tsis yog nws inhibit lossis ntxias cov enzymes no, kev sib cuam tshuam ntawm Galvus nrog tshuaj uas yog cov substrates, inhibitors, lossis inducers ntawm P450 yog qhov tsis zoo. Nrog rau kev siv vildagliptin tib lub sij hawm tseem tsis cuam tshuam rau qhov tshuaj ntawm cov tshuaj uas hloov cov enzymes: CYP1A2, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP2E1 thiab CYP3A4 / 5.
Noj ntau dhau
Cov tsos mob thaum siv cov tshuaj ntawm koob tshuaj 400 mg /, cov leeg mob tuaj yeem pom, tsis tshua muaj mob ntsws thiab cov kab mob hloov mus los ntev, ua npaws, edema thiab ib qho kev hloov pauv hauv lipase concentration (2 zaug siab dua VGN). Nrog rau qhov nce ntawm koob Galvus txog rau 600 mg /, kev txhim kho ntawm edema ntawm qhov kawg nrog paresthesias thiab kev nce ntxiv hauv qhov kev coj siab ntawm CPK, ALT, C-reactive protein thiab myoglobin yog tau.Tag nrho cov tsos mob ntawm kev haus ib ce thiab hloov cov kev hloov hauv chaw kuaj ploj tom qab tsis siv tshuaj.
Kev Kho Mob: tshem tawm cov tshuaj ntawm lub cev los ntawm kev lim ntshav yog qhov tsis zoo. Txawm li cas los xij, lub ntsiab hydrolytic metabolite ntawm vildagliptin (LAY151) tuaj yeem tshem tawm hauv lub cev los ntawm hemodialysis.
Cia rau cov neeg mob
Hauv qhov chaw tsaus li ntawm qhov kub thiab txias tsis siab tshaj 25 ° C.
Cov dej siab Galvus hloov hauv cov ntsiav tshuaj
Vipidia (ntsiav tshuaj) Ntsuas: 88 Sab saum toj
Cov analogue ntau kim dua los ntawm 182 rubles.
Vipidia yog tus neeg sawv cev hypoglycemic hauv ntsiav tshuaj nrog alogliptin. Muab kev txo qis hauv glycosylated hemoglobin thiab piam thaj. Nws yog qhia nyob rau hauv cov ntaub ntawv ntawm hom 2 mob ntshav qab zib mellitus nyob rau hauv daim ntawv ntawm monotherapy, zoo li nyob rau hauv kev sib txuas ua ke nrog kev kho mob nrog lwm tus neeg mob ntshav qab zib. Cov tshuaj noj zoo yog 25 mg / hnub, noj tsis hais zaub mov dab tsi. Contraindicated nyob rau hauv cov kab mob ntshav qab zib ketoacidosis, yam 1 mob ntshav qab zib mellitus, mob plawv heev rau lub plawv tsis ua hauj lwm, lub raum thiab lub siab ua haujlwm. Cov mob tshwm sim tuaj yeem suav cov mob taub hau, mob rau hauv epigastrium, tawm pob, ua mob rau kis ntawm ENT plab hnyuv siab raum. Cov menyuam yaus hnub nyoog qis dua 18 xyoo thiab poj niam cev xeeb tub tsis tau raug samfwm vim tias tsis muaj cov ntaub ntawv ntawm daim ntawv thov.
Cov analogue kim dua los ntawm 857 rubles.
Trazhenta - tshuaj noj kom ntshav qab zib tsawg. Nws yog raws li hauv linagliptin molecule. Txo cov ntau lawm cov piam thaj hauv lub siab, normalizes qib ntawm cov piam thaj hauv cov ntshav. Ntshav qab zib Hom 2 yog qhov qhia txog kev siv tshuaj kho mob thiab kho kev sib xyaw ua ke. Kev xaiv koob yog tus kheej. Siv tsis tau rau hom ntshav qab zib hom 1, kev hnov mob ib leeg, ketoacidosis uas mob ntshav qab zib. Ntawm qhov tsis xav tau tshwm sim tej zaum yuav yog hnoos, pancreatitis, ntswg ntswg. Siv tsis tau rau cov menyuam hnub nyoog qis dua 18 xyoo thiab rau cov poj niam cev xeeb tub.
Cov analogue yog kim dua los ntawm 981 rubles.
Onglisa - siv tshuaj kho mob ntshav qab zib. Cov tshuaj ua kom nquag plias ntawm cov ntsiav tshuaj yog saxagliptin. Txo glucagon, ntshav qab zib ua ntej thiab tom qab noj mov. Nws yog tshuaj rau tus mob ntshav qab zib hom 2 ntxiv rau kev noj zaub mov noj hauv cov qauv ntawm kev kho mob hlwb thiab sib xyaw ua ke. Koob txheej txheem yog nyob ntawm kev ntsuas. Hom 1 mob ntshav qab zib mellitus, kev tswj hwm nrog insulin, ketoacidosis yog contraindications. Kev o, mob taub hau, txhaws ntswg, mob caj pas yog ua tau nrog kev kho mob Onglisa. Tsis muaj kev paub dhau los hauv kev ntsuas mob thiab poj niam cev xeeb tub, yog li ntawd, nws tsis yog siv hauv pawg no.
Cov analogue yog kim dua los ntawm 1418 rubles.
Januvia yog lwm qhov tshuaj hypoglycemic uas muaj cov sitagliptin. Nws raug nqi ntau dua Galvus nrog tib tus naj npawb ntawm cov ntsiav tshuaj hauv pob. Txhawb kev tsim cov khoom ntawm glucagon, txo glycemia. Nws tsuas yog siv rau ntshav qab zib hom 2. Cov koob tshuaj tau hloov kho nyob ntawm cov ntshav piam thaj. Tsis siv rau hom 1 mob ntshav qab zib, mob siab dhau. Mob taub hau, raws plab, xeev siab, mob tej pob txha, mob caj pas sab saud tau pom thaum kho. Zoo li cov tshuaj saum toj no, nws tsis raug xaj rau cov menyuam yaus hnub nyoog qis dua 18 xyoo thiab poj niam cev xeeb tub.
Galvus Met
Metformin yog ib cov tshuaj siv thoob plaws rau cov ntshav qab zib hom 2, yog tau sau tseg rau yuav luag txhua tus neeg mob. Rau lub sijhawm ntev ntawm kev siv, tsis tsuas yog cov txiaj ntsig ntawm cov tshuaj no tau paub tseeb, tab sis kuj pom ntau cov txiaj ntsig zoo ntawm lub plawv, cov hlab ntsha, ntshav lipid spectrum. Raws li cov lus pom zoo los ntawm cov koom tes ntawm cov kws kho ntshav qab zib, lwm yam tshuaj tau sau tseg tsuas yog thaum metformin tsis txaus los them rau cov ntshav qab zib.
Galvus Met ntsiav tshuaj ua ke, lawv muaj metformin thiab vildagliptin. Kev siv cov tshuaj tuaj yeem txo cov ntsiav tshuaj, uas txhais tau hais tias nws txo qhov kev pheej hmoo ntawm ploj ib qho ntawm lawv. Qhov tsis zoo ntawm cov tshuaj yog tus nqi ntau dua ntawm kev kho mob piv rau ib koob nyias muaj nyias ntawm Galvus thiab metformin.
| Dosages Galvus Met, mg | Tus nqi nruab nrab rau 30 tabs, rubles. | Tus nqi ntawm 30 ntsiav tshuaj ntawm Galvus thiab Glucofage ntawm tib lub tshuaj, rubles. | Nqi nce,% |
| 50+500 | 1550 | 875 | 44 |
| 50+850 | 890 | 43 | |
| 50+1000 | 950 | 39 |
Kev sib piv thiab hloov chaw
Txij li Galvus yog ib yam tshuaj tshiab, kev tiv thaiv patent tseem siv rau nws. Lwm cov tuam ntxhab tsis tuaj yeem tsim cov ntsiav tshuaj nrog tib cov tshuaj qub qub, pheej yig hauv tsev analogues tsis muaj nyob.
DPP-4 cov tshuaj tiv thaiv thiab ua kom zoo zuj zus tuaj yeem ua rau Galvus hloov chaw:
- sitagliptin (Januvius, Xelevia, Yasitara),
- saxagliptin (Onglisa),
- exenatide (Baeta),
- liraglutide (Viktoza, Saksenda).
Txhua tus ntawm cov counterparts yog qhov kim, tshwj xeeb tshaj yog Baeta, Viktoza thiab Saksenda. Tsuas yog cov tshuaj Lavxias ntawm cov saum toj no yog Yasitar los ntawm Pharmasintez-Tyumen. Cov tshuaj tau pib rau thaum xaus ntawm 2017, nws tseem tsis tau muaj nyob hauv cov chaw muag tshuaj.
Yog hais tias tus neeg mob ua raws li kev noj haus, siv Galvus Met ntawm qhov ntau kawg, thiab qab zib yog tseem siab dua li ib txwm, tom qab ntawd tus txiav yog ze ze rau kev qaug. Hauv qhov xwm txheej no, koj tuaj yeem sim ua kom spur synthes ntawm insulin nrog sulfonylurea derivatives, tab sis feem ntau yuav, lawv tseem yuav muaj txiaj ntsig tsis txaus. Yog tias koj cov insulin tsis ua haujlwm lawm, tus mob ntshav qab zib xav tau kev hloov tshuaj insulin. Tsis txhob laug sij hawm rau nws thaum pib. Teeb meem ntawm ntshav qab zib pib muaj txawm tias cov qabzib tsawg dua.
Galvus lossis Metformin
Hauv Galvus Mete, cov tshuaj nquag yog sib npaug. Lawv ob leeg cuam tshuam rau cov suab thaj, tab sis nqa tawm lawv cov kev txiav txim los ntawm ntau cov sib txawv. Metformin - feem ntau yog vim muaj qhov txo qis hauv cov tshuaj insulin, vildagliptin - nce ntxiv ntawm cov tshuaj insulin. Lawm, cov nyhuv ntau ntawm cov teeb meem muaj txiaj ntsig zoo dua. Raws li cov txiaj ntsig ntsuas, ntxiv ntawm Galvus rau metformin txo glycated hemoglobin los ntawm 0.6% hauv 3 lub hlis.
Nws ua rau tsis muaj txiaj ntsig los txiav txim siab tias Galvus lossis metformin zoo dua. Metformin noj thaum pib ntawm tus kabmob nrog rau kev noj zaub mov zoo thiab kev ua kis las, ntawm cov tshuaj, thawj Glucofage lossis cov neeg ua haujlwm zoo ntawm Siofor zoo dua. Thaum nws tsis txaus, Galvus ntxiv rau qhov kev kho mob lossis tshuaj ntshiab metformin Galvus Metom yog hloov.
Pheej yig lwm txoj rau Galvus
Ntsiav tshuaj yog qhov pheej yig dua li Galvus, tab sis tib qho kev nyab xeeb thiab siv tau zoo tsis muaj nyob. Koj tuaj yeem ua kom qeeb qeeb kev loj hlob ntawm cov ntshav qab zib nrog kev cob qhia tsis tu ncua, kev noj zaub mov tsis muaj qab hau, thiab pheej yig metformin. Qhov zoo dua them nyiaj rau ntshav qab zib, lwm cov tshuaj ntev dua yuav tsis xav tau.
Zoo-paub sulfonyl urea npaj, zoo li Galvus, txhim kho cov tshuaj insulin. Cov no suav nrog qhov muaj zog, tab sis tsis muaj kev nyab xeeb Maninil, qhov ntau dua Amaryl thiab Diabeton MV. Lawv tsis tuaj yeem suav tias yog analogues ntawm Galvus, txij li qhov mechanism ntawm kev ua ntawm cov tshuaj yog txawv heev. Cov khoom siv ntawm sulfonylureas ua rau lub ntsej muag tsis txaus, ua rau ntau dua ntawm cov txiav, ua kom sai ntawm kev rhuav tshem cov beta hlwb, yog li thaum koj coj lawv, koj yuav tsum npaj rau qhov tseeb tias ob peb xyoos koj yuav xav tau kev kho tshuaj insulin. Galvus tiv thaiv kev tuag ntawm cov beta hlwb, ncua sijhawm ua haujlwm ntawm cov txiav.
Nkag Tawm Cov Cai
Koob tshuaj pom zoo Vildagliptin:
Tus kws kho mob ntawm Kev Tshawb Fawb Kev Kho Mob, Lub Taub Hau ntawm lub koom haum ntawm Diabetology - Tatyana Yakovleva
Kuv tau kawm mob ntshav qab zib tau ntau xyoo. Nws yog txaus ntshai thaum muaj coob tus neeg tuag, thiab haj yam ua rau neeg xiam vim ntshav qab zib.
Kuv maj nrawm nroos los qhia txoj xov zoo - Endocrinological qhov chaw tshawb fawb ntawm Lavxias Academy ntawm Medical Science tau tswj los tsim cov tshuaj uas kho cov ntshav qab zib kom tiav. Thaum lub sijhawm, cov hauj lwm zoo ntawm cov tshuaj no tau nce mus txog 98%.
Lwm qhov xov xwm zoo: Lub Tsev Haujlwm Saib Xyuas Kev Noj Qab Haus Huv tau txais kev nyab xeeb qhov kev saws me nyuam ntawm cov haujlwm tshwj xeeb uas them rau cov nqi tshuaj ntau. Hauv Lavxias, cov neeg mob ntshav qab zib tuaj yeem tau txais nws ua ntej Lub Ob Hlis 17 - Rau tsuas yog 147 rubles!
>> KAWM NTXIV TXOG TXUJ CI
- 50 mg thaum pib ntawm kev tswj hwm, thaum siv ua ke nrog sulfonylurea kev npaj, lawv nqa ib ntsiav tshuaj thaum sawv ntxov,
- 100 mg rau mob ntshav qab zib mellitus ntau, suav nrog kev kho mob insulin. Cov tshuaj tau muab faib ua 2 koob.
Rau cov tshuaj metformin, qhov tshuaj noj kom zoo tshaj yog 2000 mg, qhov ntau tshaj yog 3000 mg.
Galvus tuaj yeem qaug cawv ntawm ib qho khoob lossis hauv plab tag nrho, Galvus Met - tsuas yog nrog zaub mov noj.
Txo cov kev pheej hmoo ntawm phiv
Raws li cov neeg mob ntshav qab zib, Galvus Met tau zam me ntsis zoo dua li cov ntshiab metformin, tab sis nws kuj feem ntau ua rau muaj teeb meem plab zom mov: raws plab, ntuav, thiab tsis xis nyob hauv plab. Tsis kam kho nrog cov tsos mob zoo li no tsis tsim nyog. Txo kom txo qhov hnyav ntawm cov kev mob tshwm sim, koj yuav tsum muab lub sijhawm rau lub cev kom yoog nrog cov tshuaj. Kev kho mob pib nrog qhov kev noj cov tsawg kawg, maj mam nce nws kom zoo.
Ib qho piv txwv algorithm rau kev nce ntxiv koob tshuaj:
- Peb yuav cov ntawv ntim ntawm Galvus Met ntawm qhov ntau tshaj me me (50 + 500), thawj lub lis piam peb noj 1 lub tshuaj.
- Yog tias tsis muaj teeb meem plab zom mov, peb hloov mus rau qhov tshuaj noj ob zaug thaum sawv ntxov thiab yav tsaus ntuj. Koj tsis tuaj yeem haus Galvus Met 50 + 1000 mg, txawm tias muaj ntau npaum li cas.
- Thaum pob ntawv tiav, yuav 50 + 850 mg, haus 2 ntsiav tshuaj.
- Yog tias cov piam thaj tseem nyob siab tshaj hauv tus cai, tom qab qhov kawg ntim, peb hloov mus rau Galvus Met 50 + 1000 mg. Koj tsis tuaj yeem nce ntxiv qhov ntau lawm.
- Yog tias them nyiaj rau ntshav qab zib tsis txaus, peb ntxiv sulfonylurea lossis tshuaj insulin.
Kev rog cov neeg mob ntshav qab zib tau hais kom noj ntau tshaj plaws ntawm metformin. Hauv qhov no, thaum yav tsaus ntuj, lawv ntxiv rau haus dej Glucofage lossis Siofor 1000 lossis 850 mg.
Yog tias kev yoo mov qab zib kom nce siab, thiab tom qab noj mov ntau zaus hauv kev txwv ib txwm muaj, kev kho tuaj yeem hloov kho: haus Galvus ob zaug, thiab Glucofage Ntev - ib zaug thaum yav tsaus ntuj ntawm kev noj tshuaj ntawm 2000 mg. Ntev Glucofage yuav ua haujlwm nquag txhua hmo, yog li ua kom cov glycemia zoo thaum sawv ntxov. Txoj kev pheej hmoo ntawm hypoglycemia yog xyaum tsis tuaj.
Cawv tau zoo
Hauv cov lus qhia rau Galvus, cawv tsis tau hais txog, uas txhais tau tias dej cawv tsis cuam tshuam rau lub txiaj ntsig ntawm cov ntsiav tshuaj thiab tsis nce qib kev phiv. Tab sis thaum siv Galvus Meta, kev quav cawv thiab haus dej cawv yog contraindicated, txij li lawv zoo heev ua rau muaj feem ntawm lactic acidosis. Ib qho ntxiv, haus cawv tsis tu ncua, txawm tias me me xwb, ua rau mob ntshav qab zib hnyav ntxiv. Tsis tshua muaj kev haus cawv tau txiav txim siab ua rau muaj kev nyab xeeb yog tias qhov sib xyaw ntawm intoxication tsis mob sib khuav. Qhov nruab nrab, nws yog 60 g cawv rau cov poj niam thiab 90 g rau txiv neej.
Qhov cuam tshuam ntawm qhov hnyav
Galvus Met tsis muaj qhov cuam tshuam rau qhov hnyav, tab sis ob qho tib si cov khoom xyaw hauv nws cov muaj pes tsawg leeg txhim kho cov rog rog thiab txo qhov qab los noj mov. Raws li kev txheeb xyuas, ua tsaug rau metformin, cov neeg mob ntshav qab zib tuaj yeem poob ob peb phaus. Cov txiaj ntsig tau zoo tshaj plaws yog nyob rau hauv cov ntshav qab zib muaj qhov ntau dhau ntawm lub cev nyhav thiab tshaj tawm insulin tsis kam.
Metformin yog dab tsi?
Lub hauv paus ntawm cov ntshav qab zib mellitus ntawm hom thib ob yog qhov ua txhaum ntawm qhov rhiab ntawm receptors hauv plab hnyuv siab raum thiab cov ntaub so ntswg mus rau insulin, lossis insulin tsis kam.
Coated ntsiav tshuaj nrog biconvex nto, ntsuab, cov ntsiav tshuaj nrog qhov ntau npaum li 500 mg thiab 1000 mg - nrog kev pheej hmoo, qhov ntau ntawm 850 mg - tsis muaj kev pheej hmoo.
Peb nco ntsoov ua ntej tias txhua cov tshuaj tawm rau cov ntshav qab zib muaj ntau tus naj npawb ntawm cov nyhav thiab cov kev mob tshwm sim.
Tsis tas li, cov tshuaj uas peb piav qhia no tsis nyab xeeb, tab sis peb yuav tham txog qhov no me ntsis tom qab.
Nws yog hais txog cov tshuaj hypoglycemic (chav kawm loj loj), i.e. cov uas muaj peev xwm ua kom tsuj, txo qis cov piam thaj.
Cov nyhuv no tau pom yuav luag tam sim ntawd tom qab noj npaj muaj metformin hydrochloride. Qhov no tshwm sim vim tias nws txhim kho qhov rhiab heev ntawm cov hlwb rau insulin thiab kev noj haus, qabzib cov qog nce ntxiv. Yog lawm, nyob rau hauv tus naj npawb ntawm cov neeg mob, nrog rau qhov no, muaj kev siv cov piam thaj ntau ntxiv (rau ib tug neeg, kwv yees li 50%).
Qee lub sij hawm cov neeg mob yws yws tias cov tshuaj uas kws kho mob tsis pab, uas yog, tsis tiv nrog nws lub luag haujlwm tseem ceeb - kev ua haujlwm sai sai. Qhov no tuaj yeem tshwm sim rau ntau yam. Hauv qab no kuv sau cov laj thawj vim li cas metformin yuav tsis tuaj yeem pab.
- Metformin tsis yog qhov tsim nyog rau ua pov thawj
- Tsis txaus noj
- Tshuaj Hla
- Tsis ua kom yoo noj zaub mov noj thaum noj tshuaj metformin
- Ib leeg loog
Qee lub sij hawm nws yog qhov txaus los kho qhov ua yuam kev ntawm kev noj thiab cov suab thaj txo cov txiaj ntsig yuav tsis ua rau koj nyob tos.
Ntawm no kuv xav xaus kuv tshooj. Sau npe yuav ua rau blog tshiab kom tau txais cov ntaub ntawv tuaj yeem ntseeg tau thiab muaj txiaj ntsig ntsig txog ntshav qab zib thiab lwm yam. Nyem rau ntawm cov khawm nyees khawm. tes hauj lwm yog tias koj nyiam tsab xov xwm thiab pom koj sai sai!
Nrog kev sov siab thiab kev saib xyuas, tus kws kho mob endocrinologist Lebedeva Dilyara Ilgizovna
"Metformin" thiab nws cov tshuaj analogues - cov tshuaj hypoglycemic nyob rau hauv kev kho mob ntshav qab zib - feem ntau yog yam thib ob, tab sis qee qhov, cov tshuaj raug coj thiab thawj hom. Txij li nws cov lus qhia hauv xyoo 1957, Metformin tau tseem nyob rau hauv cov tshuaj kho mob ntshav qab zib, tshwj xeeb tshaj yog muaj teeb meem xws li kev rog dhau.
Cov tshuaj Insulin pab txhawb kev tso nyiaj ntawm cov rog, thiab Metformin, txo cov tshuaj insulin hauv lub cev, pab ua kom tshem tau. Nws yog vim qhov kev txiav txim no uas ntau tus neeg siv Metformin ua cov ntsiav tshuaj noj.
Cov kev tiv thaiv ntawm Metformin
Dab tsi qab nws cov teebmeem kev kho mob?
- Cov tshuaj txhim kho cov tshuaj insulin rhiab heev,
- Cov tshuaj tiv thaiv glycemic,
- Fibrinolysis zoo tuaj
- Microcirculation hauv peripheral cov ntaub so ntswg yog qhib kom ua huaj,
- Endothelial kawg ua haujlwm poob qis
- Tawm tsam cov keeb kwm yav dhau los ntawm metformin, hyperglycemia txo qis,
- Kev tsim cov khoom kawg glycation yog txo qis,
- Qhov ceev ntawm cov ntshav txhaws txo qis
- Oxidative kev nyuaj siab yog neutralized,
- Muaj nuj nqi zoo ntawm atherogenesis thiab dyslipidemia.
Cov tshuaj txo qis kev pheej hmoo ntawm cov hlab ntshav tshwm sim hauv cov neeg mob ntshav qab zib nrog hom thib ob, thiab cov txiaj ntsig ntawm kev paub txog metabolic cia koj txuag txiaj ntsig ntev.
Kev kho mob nrog Metformin thiab nws cov txiaj ntsig muab qhov txo qhov tseem ceeb hauv glycemia.
Piv nrog tshuaj sib piv thiab lwm cov tshuaj ntxiv, Metformin muaj qhov tsis ua hauj lwm rau qhov hnyav thiab tseem pab txo nws.
Cov tshuaj tiv thaiv kab mob Metformin muaj cov khoom qab zib-txo qis, uas txhais tau hais tias nws yuav tsis txhawb qhov kev tsim cov tshuaj insulin endogenous thiab ua kom dhau ntawm lub txiav, uas twb ua haujlwm ntawm qhov txwv ntawm nws lub peev xwm.
Cov txheej txheem sib tsoo thiab cov phom sij uas yuav muaj
Nrog rau cov txiaj ntsig saum toj no ntawm metformin, qhov yuav ua rau muaj kev phom sij loj rau peb lub cev los ntawm kev noj cov tshuaj no tsis suav nrog.
Qhov txaus ntshai qhov tseem ceeb ntawm cov tshuaj yog nyob rau hauv kev soj ntsuam qhov yooj yim txoj kev coj cwj pwm ntawm cov neeg mob ntshav qab zib, thaum lawv raug yuam kom tswj cov qib glycemia los ntawm kev txwv cov zaub mov muaj txiaj ntsig thiab ua kom lub cev muaj zog.
Yog tsis muaj carbohydrates, txoj kev ua haujlwm ntawm txhua qhov nruab nrog sab hauv ntawm tus neeg, tshwj xeeb tshaj yog lub hlwb, uas siv rau kev noj tsuas yog lub zog tshwj xeeb - qabzib, tsis yooj yim sua. Yog tias cov piam thaj hauv cov ntshav tsawg dua, ces nws cov ntshav yuav poob rau hauv cov qib uas yuav tseem ceeb, uas yuav ua rau koj xeev tsis xeev tau.
Tab sis hauv peb lub cev muaj cov thaub qab rov qab rau kev tswj hwm qhov ua tsis tau, uas tuaj yeem them nyiaj rau ntau dhau ntawm qhov tsis muaj qee yam. Ib qho ntawm cov tshuaj no rau qhov muaj kev pheej hmoo ntawm hypoglycemia yog hepatic gluconeogenesis, thaum glucagon pib rov qab tsim cov piam thaj los ntawm daim siab uas tau khaws cia yav tas los, tab sis thaum cov tshuaj no noj cov txheej txheem no qeeb!
Cov kab mob hu ua lactic acidosis (lossis lactic acidosis, lactic acid coma) txhim kho sai dua nrog cov teeb meem uas twb muaj lawm nrog lub raum (nrog cov ntshav qabzib ua kom tsis muaj kabmob, uas tsim kho mus rau kev mob raum tsis ua haujlwm), txij li metformin hydrochloride ntau zuj zus tuaj hauv cov qog ua haujlwm, cov leeg, nplooj siab, thiab lub raum. thiab raug cais tawm tshwj xeeb los ntawm ob lub raum.
Yog tias lawv txoj haujlwm cuam tshuam, 90% ntawm cov tshuaj no tseem tsis tau hloov pauv ntawm tib neeg lub cev. Tab sis nrog tag nrho cov no, qhov teeb meem sib npaug hauv cov ntshav qab zib - ketoacidosis, raws li txoj cai, tsis loj hlob.
Yog li, nws yog qhov txaus ntshai rau noj cov tshuaj metformin uas muaj mob thaum lub raum tsis ua haujlwm los yog muaj teeb meem rau lub raum, tab sis ntau tus kws kho mob endocrinologist tseem muab tshuaj, hais tias txo qis glycemia thiab kev tawm tsam cov tshuaj insulin kuj yog qhov tseem ceeb, vim tias muaj ntshav qab zib ntau ntau, ntau yam kev nyuaj tshwm sim, uas ua rau muaj kev tuag ntau ntawm cov ntshav qab zib.
Hauv kev xyaum thoob ntiaj teb, cov tshuaj metformin uas muaj cov tshuaj noj yog muab tshuaj sai tom qab kuaj pom tau thiab nws muaj peev xwm tiag tiag los ua kom ntev mus rau lub neej ntawm cov ntshav qab zib. Hauv teb chaws Russia, raws li txoj cai, feem ntau yog kev kho mob twb dhau los ntawm theem pib ntawm tus kab mob, thaum metformin dhau los ua lwm qhov laj thawj ntxiv rau qhov kev mob tsis zoo ntawm cov neeg mob ntxiv nrog rau kev mob ntshav qab zib ntau ntxiv nyob rau lub sijhawm thaum nws mob pes tsawg (hauv kev noj tshuaj me me) tuaj yeem txhim kho kev noj qab haus huv thiab ncua tiv tsis taus.
Nrog rau cov mob ntshav qab zib me me, qhov tsis kam ntawm insulin-cov ntaub so ntswg muaj cai, yog li ntawd, kev kho tseem ceeb yog txo qis tshuaj insulin. Dab tsi peb tus phab ntsa tau yooj yim tiv nrog txawm tias siv tshuaj me me, uas tsis muaj peev xwm ua rau tib neeg lub cev hnyav heev.
Tab sis, hmoov tsis zoo, cov peev txheej ntawm insulin secretion hauv cov ntshav qab zib hom 2 tau ploj mus lawm (i.e., insulin tsis tsim tawm ntawm nws tus kheej hauv qhov ntim tsim nyog), tom qab ntawd cov kws kho mob tau yuam cov tshuaj insulin secretion rau kev kho - cov no yog sulfanilamides.
Tom qab, yog tias lawv ua pov thawj tias qhov tsis muaj txiaj ntsig, tom qab ntawd cov tshuaj insulin feem ntau suav nrog kev kho mob, feem ntau yog ua ke nrog cov tshuaj uas ua rau muaj kev cuam tshuam cov insulin-cuam tshuam cov ntaub so ntswg rau insulin (qhov no yog peb lub cim tseem ceeb nrog koj).
Lwm cov kev phiv suav nrog:
- teeb meem mob hnyuv (xeev siab, ntuav, tsam plab, roj, raws plab)
- kev tsis nco qab
- ua txhaum ntawm saj (piv txwv li, cov xim hlau hauv cov zaub mov tau noj)
- Vitamin B12 tsis muaj peev xwm (yog li ntawd, pom zoo ntxiv kom pom zoo
cov vitamins rau ntshav qab zib
Npaum licas
Cov tshuaj muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj. Cov ntsiav tshuaj tau ntim rau hauv blister pob ntawv ua los ntawm polyvinyl chloride thiab aluminium ntawv ci. Txhua pob ntawv muaj 10 ntsiav tshuaj.
Rau pob contour tau muab tso rau hauv lub thawv ntawv thawv, uas tseem muaj cov lus qhia rau kev siv. Ib daim npav card ntawm cov tshuaj muaj 60 ntsiav tshuaj.
Khaws cov tshuaj rau hauv qhov chaw tiv thaiv los ntawm lub hnub ncaj qha ntawm qhov kub tsis tshaj 25 degrees Celsius. Cov tshuaj yuav tsum muab khaws cia kom deb ntawm cov menyuam yaus.
Lub txee lub neej ntawm cov khoom kho mob yog peb xyoos. Cov tshuaj yog muag hauv cov khw muag tshuaj los ntawm cov tshuaj noj.
Feem ntau ntawm kev tshuaj xyuas pom los ntawm cov neeg mob siv cov tshuaj no yog qhov zoo. Cov tsos ntawm kev tshuaj xyuas tsis zoo yog feem ntau cuam tshuam nrog kev ua txhaum cov lus qhia rau kev siv tshuaj lossis thaum muaj kev ua txhaum ntawm cov lus pom zoo tau txais los ntawm tus kws kho mob tuaj koom. Ntau zaus muaj cov kev txheeb xyuas ntawm cov neeg mob, uas qhia tau tias kev siv cov tshuaj txo nws lub cev hnyav.
Cov chaw tsim tshuaj loj nyob rau hauv Lavxias teb sab yog Ozone LLC.
Tus nqi ntawm cov tshuaj nyob rau hauv thaj chaw ntawm Lavxias teb sab yog nyob ntawm lub network ntawm cov khw muag tshuaj thiab thaj chaw uas cov tshuaj muag. Tus nqi nruab nrab ntawm cov tshuaj hauv Lavxias Lavxias muaj txog 105 txog 125 rubles rau ib pob.
Feem ntau cov tso tawm ntawm Metformin 500 hauv Lavxias teb chaws yog cov hauv qab no:
- ,
- Glycon
- Glyminfor,
- Glyformin
- Glucophage,
- Glucophage Ntev,
- Methadiene
- Metospanin
- Metfogamma 500,
- Metformin
- Metformin Richter,
- Metformin Teva,
- Metformin hydrochloride,
- Nova Met
- NovoFormin,
- Siofor 500,
- Sofamet
- Txog rau cov,
- Rau menyuam yaus.
Cov kab mob sib xyaw ua ke ntawm Metformin zoo sib xws hauv kev teeb tsa thiab hauv cov khoom siv nquag.
Cov ntau ntawm cov kab mob tam sim no ntawm Metformin pub rau, yog tias tsim nyog, tus kws kho mob koom nrog tau yooj yim xaiv cov tshuaj tsim nyog thiab hloov Metformin nrog lwm cov cuab yeej kho mob. Txog yuav ua li cas Metformin ua haujlwm nyob rau hauv cov ntshav qab zib, tus kws tshaj lij yuav qhia hauv cov yeeb yaj kiab hauv tsab xov xwm no.
Tus nqi ntawm cov tshuaj no yog los ntawm 100 txog 250 rubles, nyob ntawm cov ntsiab lus ntawm cov tshuaj nquag.
Kev ua lag luam pharmacological muaj ntau cov ntsiav tshuaj nrog cov piav qhia nquag nquag khoom xyaw.
Txawm hais tias sib txawv ntawm cov koom haum pabcuam, cov ntsiav tshuaj tsis kim. Piv txwv li, tus nqi hauv Lavxias zoo li 90 txog 260 rubles.
Tus nqi ntawm Metformin los ntawm lwm cov tuam txhab muag tshuaj txawv teb chaws tsis txawv ntau.
Tus nqi ntawm Metformin los ntawm ntau lub tuam txhab txawv teb chaws yog:
- Slovakia - ntawm 130 txog 210 rubles.
- Hungary - los ntawm 165 txog 260 rubles.
- Poland - ntawm 75 txog 320 rubles.
Kev npaj muaj metformin hydrochloride feem ntau muaj rau cov theem nrab. Koj tuaj yeem txuag nyiaj los ntawm kev yuav tshuaj ntsiav ntshav qab zib online. Rau Metformin, tus nqi nyob ntawm qhov ntau npaum:
- 500 mg (60 ntsiav tshuaj) - los ntawm 90 txog 250 rubles,
- 850 mg (60 ntsiav tshuaj) - los ntawm 142 txog 248 rubles,
- 1000 mg (60 ntsiav tshuaj) - los ntawm 188 txog 305 rubles.
Raws li koj tuaj yeem pom, tus nqi ntawm tus neeg sawv cev hypoglycemic Metformin tsis yog qhov siab heev, uas yog qhov loj ntxiv.
Tus neeg mob tshuaj xyuas txog cov tshuaj feem ntau zoo. Metformin txo cov ntshav qab zib kom huv si thiab tsis ua rau lub qog ntshav qab zib. Cov kws kho mob kuj pom zoo siv cov tshuaj tiv thaiv kab mob siab. Kev siv Metformin tas li rau kev tiv thaiv kab mob plawv tau them tas mus.
Qee cov neeg uas tsis muaj ntshav qab zib noj tshuaj pab txo qhov hnyav. Cov kws txawj tsis pom zoo tsis pom zoo kom siv cov tshuaj no rau qhov poob phaus rau cov neeg noj qab haus huv.
Tus nqi nruab nrab ntawm METFORMIN hauv cov khw muag tshuaj (Moscow) yog 110 rubles.
Tus nqi nruab nrab ntawm Metformin ntsiav tshuaj hauv khw muag khoom hauv Moscow txawv ntawm 117-123 rubles.
Glucophage (Metformin) rau qhov poob phaus. Thaum nws tsis tuaj yeem siv txhua qhov
Cov kws tshwj xeeb pom zoo siv cov cuab yeej no rau kev kho mob ntawm ntau yam kab mob.
Bobkov E.V., kws kho mob feem ntau, hnub nyoog 45 xyoos, Ufa: "Cov tshuaj zoo tsim siv los kho hom ntshav qab zib hom 2."
Danilov S.P., kws kho mob dav dav, 34 xyoo, Kazan: “Ntau xyoo dhau los, nws tau qhia tias nws qhov kev ua tau zoo hauv kev sib ntaus tawm tsam tshaj qhov hnyav. Pab rau lub sijhawm luv luv kom ua tiav cov txiaj ntsig. "
Dmitry, 43 xyoo, Vladivostok: “Kuv tau mob ntshav qab zib hom 2. Kuv tau noj cov tshuaj no nrog rau cov tshuaj insulin rau li ib xyoos. Txo cov ntshav qab zib. "
Vladimir, hnub nyoog 39 xyoo, Ekaterinburg: “Tau ntev kuv tau noj Glibenclamide, tab sis tom qab ntawv Metformin tau raug tshuaj. Nws nqa tau yooj yim, thiab cov piam thaj hauv ntshav rov qab los, cov mob zoo los lawm. ”
Svetlana, hnub nyoog 37 xyoo, Rostov-on-Don: “Kuv tau yuav cov tshuaj no ntawm cov kws qhia zaub mov noj haus. Kuv tsis xav tias qhov zoo tshwm sim. "
Valeria, 33 xyoo, Orenburg: “Txij li thaum me nyuam yaus, nws nquag mus rog. Tus kws kho mob mus kawm qhia Metformin. Tom qab ib hlis, Kuv tsis noj nws, vim hais tias quaj los ntawm kiv taub hau thiab xeev siab. "
Metformin muab cov suab thaj txo qis rau hauv txhua tus neeg mob. Ib qho kev cuam tshuam tsis zoo ntawm cov tshuaj yog nquag muaj kev phiv los ntawm cov hnyuv.
Txhawm rau tshem tawm lawv, Kuv xav kom hloov mus rau cov ntsiav tshuaj tso tawm qeeb zog, haus lawv ua ntej yuav mus pw. Tshuaj yej lossis dej nrog txiv qaub pab tau zoo los ntawm kev mob thaum sawv ntxov thiab saj hauv lub qhov ncauj.
Kuv feem ntau hais kom 2 lub lis piam, lub sijhawm ntawd cov tsos mob feem ntau ploj. Kuv tau ntsib kev tsis txaus ntseeg ntau zaus, txhua kis nws tau raws plab ntev.
Kuv tau coj cov neeg mob ntshav qab zib tau ntau xyoo thiab kuv ib txwm siv tshuaj Metformin hauv kev tso tawm thawj hom kab mob 2. Cov txiaj ntsig tau zoo tshaj plaws yog nyob ntawm cov neeg mob cov hluas uas muaj qhov hnyav heev.
Kuv nco qab ib kis, tus poj niam tuaj hauv qab 150 kg nrog hais tawm tsam rog rog. Nws tau yws txog qhov tsis muaj peev xwm ua kom poob ceeb thawj, txawm hais tias cov lus qhia ntawm calories txhua hnub, raws li nws, txawm tias ib txwm tsis tau mus txog 800 kcal.
Kev ntsuam xyuas pom tias tsis hnov lus qab zib. Kuv tau sau tawm tsuas yog siv cov vitamins ntau thiab Metformin, pom zoo tias tus neeg mob yuav ua rau muaj calorie ntau ntxiv mus txog 1,500 thiab pib mus saib pas dej peb zaug tauj ib lis piam.
Feem ntau, “txheej txheem tau pib” nyob rau hauv ib hlis. Tam sim no nws twb yog 90 kg, nws tsis yog yuav nres tom qab ntawd, kev kuaj mob ntshav qab zib tau raug tshem tawm.
Kuv tsis xav txog qhov zoo ntawd tsuas yog siv ib cov tshuaj, tab sis Metformin tau muab thawj lub zog txhawb nqa.
Thaum muab tshuaj Metformin, Kuv ib txwm hais tias nws zoo dua yog noj cov tshuaj qub. Qhov tshwm sim ntawm kev siv Indian thiab Suav generics yog ib txwm zuj zus. Cov tshuaj nyob sab Europe thiab hauv tsev yog qhov kev xaiv zoo yog tias koj tsis tuaj yeem txais Kab Mob Glucophage.
- Yuav siv cov metformin los tiv thaiv ntshav qab zib?
- Qhov tshuaj mob ntshav qab zib hom 2
- Yuav noj cov tshuaj metformin nyob rau hom ntshav qab zib hom 2 li cas
- Forew nrog ntshav qab zib mellitus
Cov yam ntxwv dav dav ntawm cov tshuaj
Ua tsaug rau vildagliptin, qhov cuam tshuam tsis zoo ntawm dipeptidyl peptidase-4 raug txo, thiab kev tsim tawm ntawm GLP-1 thiab HIP, ntawm qhov tsis sib xws, yog kho kom zoo dua. Thaum cov theem ntawm cov tshuaj no hauv cov ntshav nce siab, vildagliptin txhim kho qhov ua rau muaj kev puas tsuaj ntawm cov qe ntshav mus rau cov kua nplaum tsim, yog li ua kom cov khoom qab zib-txo cov tshuaj hormones. Nws yuav tsum raug sau tseg tias qhov muaj nuj nqis ntawm kev ua kom zoo ntawm kev ua haujlwm ntawm cov hlwb hlwb yog nyob ntawm qib ntawm lawv qhov kev rhuav tshem. Yog li, hauv cov neeg muaj ntshav qab zib li qub, vildagliptin tsis cuam tshuam rau cov kua dej insulin thiab, yog lawm, cov piam thaj ntau ntau.
Cov nquag tivthaiv tsub kom qhov feem pua ntawm GLP-1 thiab sai li sai tau nce qhov rhiab ntawm alpha hlwb ntawm islet apparatus rau qabzib. Raws li qhov tshwm sim, glucagon ntau lawm zuj zus. Kev poob qis hauv nws qib nce nyob rau thaum lub sijhawm noj mov ua rau muaj qhov nce siab ntawm cov hlwb sib luag mus rau cov ntshav qab zib.
Thaum lub sijhawm nce ntxiv ntawm cov piam thaj, cov qib glucagon thiab insulin nce ntxiv, uas ncaj qha rau cov khoom tawg ntau ntawm GLP-1 thiab HIP, cov txheej txheem ntawm cov piam thaj hauv cov qog ua rau ob qho tag nrho thaum noj mov thiab tom qab nws, uas ua rau muaj qhov txo qis hauv cov ntau ntau ntxiv ntawm cov piam thaj hauv cov ntshav. Nws yuav tsum raug sau tseg tias qhov kev tiv thaiv tsis txaus ntseeg cov ntsiab lus ntawm GLP-1 tuaj yeem ua rau cov txheej txheem ntawm lub plab zom mov, txawm hais tias nyob rau hauv kev siv txoj kev kho tsis tau ua rau muaj kev txhim kho ntawm qhov tshwm sim.
Kev siv ntau ntawm ob feem - metformin thiab vildagliptin, txawm tias zoo dua tswj cov qib ntawm glycemia hauv ntshav qab zib rau 24 teev.
Cov lus qhia rau kev siv ntsiav tshuaj
Kev noj tsis cuam tshuam rau kev siv yeeb tshuaj Galvus lossis Galvus Met.
Ua ntej siv cov tshuaj, nws yog qhov yuav tsum tau nrhiav kev pab ntawm tus kws tshaj lij uas yuav txiav txim qhov tsuas tshuaj ib tus zuj zus.
Cov ntawv sau rau cov tshuaj Galvus 50 mg qhia txog kev noj tshuaj uas tuaj yeem hloov kho los ntawm tus kws kho mob:
- Nrog rau kev kho mob monotherapy lossis hauv kev sib xyaw nrog kev kho tshuaj insulin, thiazolidinedione, metformin - 50-100 mg.
- Cov neeg muaj mob ntshav qab zib ntau dua yuav noj 100 mg ib hnub twg.
- Txais tos ntawm vildagliptin, derivatives ntawm sulfonylurea thiab metformin - 100 mg rau ib hnub.
- Kev siv ntau ntawm sulfonylurea thiab Galvus derivatives qhia ib koob tshuaj ntawm 50 mg rau ib hnub.
- Yog tias tus mob ntshav qab zib tau mob pes tsawg thiab siab lub raum ua haujlwm, cov tshuaj txhua hnub yog 50 mg.
Cov ntawv ntxig tau muaj cov ntaub ntawv hais tias qhov ntau npaum ntawm 50 mg yuav tsum noj ib lub sijhawm thaum sawv ntxov, thiab 100 mg muab faib ua ob zaug - thaum sawv ntxov thiab yav tsaus ntuj.
Dosages ntawm cov tshuaj Galvus Met kuj tau txiav txim siab los ntawm tus kws kho mob, coj mus rau hauv tus account theem ntawm qab zib thiab kev zam ntawm cov feem ntawm cov tshuaj rau tus neeg mob. Phau ntawv qhia kev siv nyiaj hauv qab no:
- nrog qhov tsis muaj txiaj ntsig ntawm kev siv vildagliptin, nws raug nquahu kom noj 50/500 mg ob zaug ib hnub,
- yog tias kev siv cov metformin yog qhov tsis muaj txiaj ntsig, noj 50/500 mg, 50/850 mg lossis 50/1000 mg ob zaug ib hnub, nyob ntawm seb cov metformin yav dhau los siv,
- nrog rau kev sib txuam tsis zoo ntawm vildagliptin thiab metformin, 50/500 mg, 50/850 mg lossis 50/1000 mg ob zaug ib hnub yog siv, nyob ntawm cov khoom siv uas siv,
- thaum lub sijhawm pib kho mob nrog tshuaj vim tsis muaj txiaj ntsig ntawm kev noj haus thiab kev tawm dag zog lub cev, noj 50/500 mg ib hnub ib zaug,
- ua ke nrog kev siv tshuaj insulin thiab sulfonylurea derivatives, ntau npaum ntawm vildagliptin yog 50 mg ob zaug ib hnub, thiab metformin zoo ib yam li nrog kev kho mob tshuaj.
Kev siv cov tshuaj yog txwv nruj rau cov neeg mob ntshav qab zib kev txom nyem los ntawm lub raum tsis ua haujlwm thiab lwm txoj kev ua haujlwm ntawm cov khoom no. Ntxiv rau, kev saib xyuas tshwj xeeb yog tsim rau cov neeg mob ntawm cov hnub nyoog laus dua (ntau dua 65 xyoos), vim lawv feem ntau muaj lub raum ua haujlwm tsawg dua.
Tus kws kho mob tuaj yeem nce qhov ntau ntxiv ntawm cov tshuaj, txawm li cas los xij, nws yog txwv tsis pub koom nrog kev kho mob ntawm koj tus kheej, qhov no tuaj yeem ua rau tsis muaj qhov xav tau thiab tsis cuam tshuam qhov tshwm sim.
Tus nqi, tshuaj xyuas thiab cov lus txhais
Cov neeg tsim cov tshuaj no yog lub tuam txhab Swiss pharmacological Novartis, uas tsim cov tshuaj nrog vildagliptin lossis nrog kev sib xyaw ntawm vildagliptin nrog metformin.
Cov tshuaj muaj peev xwm xaj online lossis mus rau qhov chaw muag tshuaj nyob ze. Tus nqi ntawm cov tshuaj nyob ntawm nws daim ntawv tso tawm. Tus nqi ntau yog raws li nram no:
- Galvus 50 mg (28 ntsiav tshuaj) - 765 rubles.
- Galvus Met 50/500 mg (30 ntsiav tshuaj) - 1298 rubles.
- Galvus Met 50/850 mg (30 ntsiav tshuaj) - 1380 rubles.
- Galvus Met 50/1000 mg (30 ntsiav tshuaj) - 1398 rubles.
Raws li koj tuaj yeem pom, cov tshuaj tsis pheej yig. Tsis yog txhua tus yuav muaj peev xwm them taus kev kho mob tas li nrog cov tshuaj no, yog li yuav tsum xaiv cov tshuaj zoo sib xws, uas yuav tham tom qab.
Raws li rau lub tswv yim ntawm cov tshuaj Galvus, lawv feem ntau zoo. Kev tshuaj xyuas ntawm feem ntau ntawm cov neeg mob noj cov tshuaj qhia tau tias tom qab 1-2 lub hlis ntawm noj Galvus, cov cim qhia qabzib rov qab tsis tau. Ntxiv rau, cov ntshav qab zib tau zoo li thaum lub sijhawm siv cov tshuaj koj tuaj yeem noj cov zaub mov txwv ua ntej. Galvus Met, ua tsaug rau nws cov metformin, pab ua kom poob phaus 3-4 hauv cov neeg mob rog rog. Txawm li cas los xij, cov tshuaj muaj ib qho loj tsis txaus - nws yog nws tus nqi siab.
Yog hais tias tus neeg mob raug txwv tsis pub siv Galvus vim yog qhov tsis sib xws los yog kev mob tshwm sim, tus kws kho mob tau sau ntawv rau lwm cov tshuaj. Cov no tuaj yeem txhais tau, uas yog, cov khoom lag luam uas muaj tib lub tshuaj nquag, qhov sib txawv tsuas yog hauv cov txuas ntxiv. Galvus Met yog tib qho lus rau Galvus; cov no yog ob qho kev npaj muaj vildagliptin.
Txawm li cas los xij, cov tshuaj no muaj ntau yam zoo sib xws uas muaj ntsis zoo sib xws hauv kev kho mob, uas yuav piav qhia tom qab.
-
Yuav ua li cas haus kvass rau cov ntshav qab zib thiab dab tsi txwv muaj?
Kuv puas tuaj yeem haus kvass nrog cov ntshav qab zib hom 2? Txhua tus tau hnov txog cov txiaj ntsig ntawm cov khoom noj khoom haus zoo, tab sis ob peb tus paub txog lub ntsiab lus. "Peb yog dab tsi peb noj" yog cov lus uas ua kom sib luag ntawm cov zaub mov thiab peb. ... -
-
-
