Cov tshuaj ntawm cov tshuaj rosuvastatin canon

Cov qauv ntawm cov tshuaj rosuvastatin canon tau nthuav tawm, cov tshuaj uas sib hloov tau ntawm lawv cov kev cuam tshuam rau lub cev, muaj ib lossis ntau cov tshuaj sib xyaw. Thaum xaiv cov lus txhais, xav txog tsis yog lawv cov nqi nkaus xwb, tab sis kuj yog lub teb chaws ntawm kev tsim khoom thiab lub koob npe ntawm cov neeg tsim khoom.

Qhia txog ntawm cov tshuaj
Sau cov analogues thiab cov nqi
Xyuas
Cov lus qhia raug rau siv

Qhia txog ntawm cov tshuaj

Rosuvastatin Canon - Kev siv tshuaj tiv thaiv hypolipidemic, xaiv cov sib tw tsim kev tiv thaiv kev tiv thaiv ntawm HMG-CoA reductase, uas hloov 3-hydroxy-3-methylglutaryl coenzyme A rau mevalonate, lub hauv ntej ntawm cov roj (cholesterol).

Lub hom phiaj tseem ceeb ntawm kev ua yog lub siab, qhov twg cov roj synthesis thiab LDL catabolism yog nqa tawm. Nws inhibits qhov kev ua haujlwm ntawm HMG-CoA reductase (90% ntawm rosuvastatin circulates hauv cov ntshav). Nws nce tus naj npawb ntawm LDL receptors nyob rau saum npoo ntawm hepatocytes, nce kev nce siab thiab catabolism ntawm LDL, uas ua rau cov inhibition ntawm cov synthesis ntawm VLDL, txo tag nrho cov LDL thiab VLDL. Txo cov ntsiab lus ntawm cov roj cholesterol LDL, cov roj cholesterol tsis yog HDL, VLDL cov roj (cholesterol), cov roj cholesterol tag nrho, triglycerides, triglycerides VLDL, apolipoprotein B (ApoV), qhov sib piv ntawm LDL cov roj cholesterol / LDL cov cholesterol, cov roj cholesterol, -HDL, ApoV / ApoA-1, nce qhov nce ntawm HDL cov roj cholesterol, ApoA-1 ntau dua.

Cov txiaj ntsig ua kom zoo dua qub hauv 1 lub lis piam tom qab pib kho, tom qab 2 lub lis piam nce mus txog 90% ntawm qhov ua tau zoo tshaj plaws, cov txiaj ntsig ua kom siab tshaj plaws feem ntau ua tiav 4 lub lis piam ntawm kev kho thiab raug tswj nrog kev siv tshuaj tsis tu ncua.

Ua tau zoo rau cov neeg mob cov neeg mob hypercholesterolemia, nrog lossis tsis muaj hypertriglyceridemia (tsis hais haiv neeg twg, poj niam lossis txiv neej), suav nrog hauv cov neeg mob ntshav qab zib mellitus thiab tsev neeg hypercholesterolemia.

Ib qho kev tiv thaiv ntxiv tau pom hauv kev sib xyaw nrog fenofibrate (hauv kev sib raug zoo los txo qis ntawm triglycerides) thiab nicotinic acid hauv lipid txo cov koob tshuaj (hauv kev piv rau qhov txo qis ntawm cov roj HDL cholesterol).

Kev ntsuas rau siv

- Thawj Fredriksen's hypercholesterolemia (hom IIa, suav nrog tsev neeg heterozygous hypercholesterolemia) lossis sib xyaw hypercholesterolemia (hom IIb) raws li kev pabcuam rau kev noj zaub mov, thaum kev noj zaub mov noj thiab lwm yam kev kho mob tsis muaj tshuaj (kev tawm dag zog, poob phaus) tsis txaus.

- Tsev neeg homozygous hypercholesterolemia yog ib qho kev txhawb ntxiv rau kev noj haus thiab lwm txoj kev kho lipid (piv txwv li, LDL apheresis), lossis nyob rau kis uas qhov kev kho mob no pab tsis tau txaus.

- Hypertriglyceridemia (yam IV raws Fredricksen) ua rau kev noj zaub mov ntxiv.

- Txhawm rau ua kom qeeb ntawm kev hloov pauv ntawm atherosclerosis ua ib qho kev txhawb ntxiv rau kev noj zaub mov hauv cov neeg mob uas pom tias muaj kev kho mob los txo qis qhov kev nqus ntawm tag nrho cov roj (cholesterol) thiab LDL-C.

- Thawj qhov kev tiv thaiv ntawm cov kev mob plawv tseem ceeb (mob hlab ntsha tawg, myocardial infarction, mob hlab ntsha tawg) hauv cov neeg laus uas tsis muaj kev kho mob ntawm txoj hlab ntshav txhaws, tab sis nrog kev pheej hmoo ntawm nws txoj kev loj hlob (dhau 50 xyoo rau cov txiv neej thiab ntau dua 60 xyoo rau cov poj niam, nce ntawm C-reactive) muaj protein ntau (ntau dua 2 mg / l) nyob rau ntawm qhov tsawg kawg ntawm ib qho kev pheej hmoo ntxiv, xws li mob ntshav siab, ntshav HDL roj tsawg, haus luam yeeb, tsev neeg muaj keeb kwm thaum pib mob ntshav siab.

Cov Yuav Tsum Muaj

Rau cov ntsiav tshuaj ntawm 10 mg thiab 20 mg:

- nce rhiab heev rosuvastatin lossis ib yam ntawm cov tshuaj,

- kab mob siab nyob hauv theem nquag, suav nrog kev pheej ua ntxiv ntawm cov ntshav ntawm transaminases thiab ib qho kev nce siab hauv kev ua haujlwm ntawm transaminases hauv cov ntshav cov ntshav (ntau dua 3 zaug piv nrog kev txwv sab sauv ntawm ib txwm),

Kev tsis zoo hauv lub raum (creatinine tshem tawm (CC) tsawg dua 30 ml / min),

poj niam: cev xeeb tub, lactation, tsis muaj txoj hau kev tsim nyog ntawm kev tswj kom tsis txhob muaj menyuam,

-patients predisposed rau kev txhim kho ntawm myotoxic muaj teeb meem,

-Cov me nyuam hnub nyoog qis dua 18 xyoo.

Txog 40 mg ntsiav tshuaj:

- nce rhiab heev rosuvastatin lossis ib yam ntawm cov tshuaj,

poj niam: cev xeeb tub, lactation, tsis muaj txoj hau kev tsim nyog ntawm kev tswj kom tsis txhob muaj menyuam,

cov neeg mob uas muaj kev pheej hmoo rau kev txhim kho myopathy / rhabdomyolysis, uas yog:

raum tsis ua haujlwm ntawm mob hnyav (CC tsawg dua 60 ml / min),

- tus kheej lossis tsev neeg keeb kwm mob leeg,

- myotoxicity hauv cov neeg mob tau txais keeb kwm ntawm lwm qhov HMG-CoA reductase inhibitors lossis fibrates,

- haus cawv ntau dhau,

-tshooj yam uas tuaj yeem ua rau kom muaj ntshav nce ntxiv ntawm rosuvastatin,

- ib txhij txais tos ntawm fibrates,

-cov neeg mob Esxias,

-Cov me nyuam hnub nyoog qis dua 18 xyoo.

Rau cov ntsiav tshuaj ntawm 10 mg thiab 20 mg:

Muaj kev pheej hmoo ntawm myopathy / rhabdomyolysis - lub raum tsis ua haujlwm, hypothyroidism, tus kheej lossis tsev neeg keeb kwm ntawm cov mob muaj keeb tiv cov leeg mob thiab keeb kwm yav dhau los ntawm cov leeg mob nrog lwm cov HMG-CoA reductase inhibitors lossis fibrates, cawv kev tiv thaiv, muaj hnub nyoog 65 xyoo, muaj mob uas tau sau tseg lub plasma concentration ntawm rosuvastatin, haiv neeg (haiv neeg Asian - Japanese thiab Suav), tib lub sij hawm siv nrog fibrates, keeb kwm ntawm daim siab mob, sepsis, leeg. kev mob ntshav siab, kev phais mob ntev, mob, hnyav kawg ntawm metabolic, endocrine lossis roj ntsha cuam tshuam, lossis kev tswj tsis tau chua leeg.

Txog 40 mg ntsiav tshuaj:

Mob raum tsis zoo (CC ntau dua 60 ml / min), hnub nyoog tshaj 65 xyoos, keeb kwm muaj kab mob siab, mob hlwb, kho ntshav siab, phais mob ntau, raug mob, hnyav kawg ntawm lub cev, endocrine lossis electrolyte cuam tshuam lossis chua leeg ntshav.

Cov neeg mob siab tsis ua haujlwm: tsis muaj ntaub ntawv lossis kev paub txog kev siv tshuaj nyob hauv cov neeg mob uas muaj tus qhab nia siab dua 9 ntawm Kev Siv Me Nyuam-Pugh ntsuas.

Siv thaum cev xeeb tub thiab thaum pub mis niam: Rosuvastatin yog contraindicated rau hauv kev xeeb tub thiab lactation. Txij li cov roj (cholesterol) thiab cov tshuaj sib tov los ntawm cov roj (cholesterol) yog qhov tseem ceeb rau kev loj hlob ntawm tus me nyuam hauv plab, qhov kev pheej hmoo ntawm kev txwv tsis pub HMG-CoA reductase ntau dua li cov txiaj ntsig ntawm kev siv tshuaj thaum cev xeeb tub.

Yog tias kuaj pom lub cev thaum muaj kev kho mob, cov tshuaj yuav tsum nres tam sim ntawd.

Cov poj niam ntawm kev muaj me nyuam hnub nyoog yuav tsum siv txoj kev ua kom muaj txiaj ntsig kom tsim nyog.

Yuav siv li cas: noj ntau thiab hom tshuaj kho

Sab hauv, lub ntsiav tshuaj yuav tsum tsis txhob zom lossis zuaj, nqos tag nrho, ntxuav nrog lub qhov dej txaus, tuaj yeem nqa tau txhua lub sijhawm ntawm hnub, tsis hais txog ntawm cov khoom noj. Yog tias nws yuav tsum tau noj cov tshuaj hauv koob tshuaj 5 mg, ib ntsiav tshuaj nrog koob tshuaj 10 mg yuav tsum tau faib.

Ua ntej pib kev kho mob nrog Rosuvastatin Canon, tus neeg mob yuav tsum pib ua raws cov qauv hypocholesterolemic noj haus thiab txuas ntxiv ua raws nws thaum kho. Cov koob tshuaj ntawm cov tshuaj yuav tsum tau xaiv ib tus zuj zus nyob ntawm lub hom phiaj ntawm txoj kev kho thiab kho cov lus teb rau kev kho mob, suav txog cov lus pom zoo tam sim no ntawm cov qib lipid.

Qhov pom zoo kom pib noj rau cov neeg mob pib noj cov tshuaj, lossis rau cov neeg mob hloov mus los ntawm kev noj lwm cov tshuaj HMG-CoA reductase inhibitors, yuav tsum yog 5 mg (1/2 ntsiav tshuaj ntawm 10 mg) lossis 10 mg ntawm cov tshuaj ib hnub ib zaug.

Nrog rau kev coj ua ib txhij ntawm Rosuvastatin Canon nrog gemfibrozil, fibrates, nicotinic acid nyob rau hauv ib koob tshuaj ntau dua 1 g / hnub, qhov pom zoo thawj zaug ntawm cov tshuaj yog 5 mg (1/2 ntsiav tshuaj ntawm 10 mg).

Thaum xaiv cov tshuaj xub thawj, ib qho yuav tsum tau taw qhia los ntawm cov roj (cholesterol) ntawm ib tus neeg thiab coj mus rau hauv qhov kev pheej hmoo ntawm cov teeb meem hlab plawv mob, thiab nws tseem yuav tsum tau ntsuas qhov muaj feem tshwm sim ntawm kev mob tshwm sim. Yog tias tsim nyog, cov koob tshuaj tuaj yeem nce ntxiv mus rau qhov ntau dua tom qab 4 lub lis piam.

Vim tias txoj kev txhim kho muaj cov kev mob tshwm sim thaum noj ib koob tshuaj 40 mg, piv nrog qhov qis dua ntawm cov tshuaj, nce qhov koob tshuaj rau 40 mg, tom qab ib qho kev noj tshuaj ntxiv yog siab dua qhov kev pom zoo pib siv rau 4 lub lis piam ntawm kev kho, tuaj yeem ua rau cov neeg mob hnyav cov degree ntawm hypercholesterolemia thiab muaj kev pheej hmoo siab ntawm cov hlab plawv mob (tshwj xeeb tshaj yog nyob rau cov neeg mob nrog tsev neeg hypercholesterolemia) uas tsis ua tiav cov txiaj ntsig ntawm kev kho mob thaum noj ib koob tshuaj 20 mg, thiab uas yuav raug soj ntsuam los ntawm cha. Pom zoo tshwj xeeb kev saib xyuas ntawm cov neeg mob tau txais cov tshuaj hauv ib koob tshuaj 40 mg yog pom zoo.

Kev siv cov koob tshuaj 40 mg tsis pom zoo rau hauv cov neeg mob uas tsis tau mus ntsib kws kho mob dhau los. Tom qab 2-4 lub lis piam ntawm kev kho mob thiab / lossis nrog kev nce ntxiv ntawm cov tshuaj, yuav tsum saib xyuas cov lipid metabolism yog qhov tsim nyog (yog tias tsim nyog, yuav tau kho qhov kev hloov tshuaj).

Cov neeg laus laus: tsis tas yuav txhaj tshuaj.

Hauv cov neeg mob uas mob mentsis lossis mob raum tsis ua haujlwm, koob tshuaj yuav tsis tas kho. Kev siv tag nrho cov tshuaj ntawm cov tshuaj yog contraindicated hauv cov neeg mob uas mob raum tsis zoo (CC tsawg dua 30 ml / min). Kev siv cov tshuaj nyob rau hauv ib koob ntawm 40 mg yog contraindicated nyob rau hauv cov neeg mob uas muaj mob me hauv lub raum tsis ua haujlwm (CC tsawg dua 60 ml / min). Rau cov neeg mob uas ua tsis zoo raum lub raum kev ua haujlwm, kev pom zoo thawj zaug ntawm 5 mg (1/2 ntsiav tshuaj ntawm 10 mg) raug pom zoo.

Cov neeg mob mob siab tsis ua haujlwm: rosuvastatin yog contraindicated hauv cov neeg mob uas muaj lub siab ua mob rau daim siab. Tsis muaj kev paub dhau los ntawm kev siv cov tshuaj hauv cov neeg mob uas lub siab tsis ua haujlwm siab tshaj 9 ntawm Child-Pugh nplai.

Thaum kawm cov tshuaj pharmacokinetic ntawm rosuvastatin hauv cov neeg mob uas yog pawg neeg sib txawv, qhov nce ntawm cov txheej txheem kev cia siab ntawm rosuvastatin ntawm cov neeg Nyij Pooj thiab Suav tau sau tseg. Qhov tseeb no yuav tsum raug coj los txiav txim siab thaum siv Rosuvastatin Canon hauv pawg neeg mob no. Thaum siv cov koob tshuaj ntawm 10 mg thiab 20 mg, qhov pom zoo pib siv rau cov neeg mob ntawm cov haiv neeg Asian yog 5 mg (1/2 ntsiav tshuaj ntawm 10 mg). Kev siv cov tshuaj hauv ib koob ntawm 40 mg yog contraindicated hauv cov neeg mob ntawm cov haiv neeg Asian.

Cov mob myopathy

Kev siv cov tshuaj ntawm ib koob ntawm 40 mg yog contraindicated nyob rau hauv cov neeg mob nrog cov ntsiab lus taw qhia kev mob siab rau kev txhim kho ntawm myopathy. Thaum thov kev noj tshuaj ntawm 10 mg thiab 20 mg, qhov pom zoo pib siv rau pawg neeg mob no yog 5 mg (1/2 ntsiav tshuaj ntawm 10 mg).

Thaum siv nrog gemfibrozil, koob tshuaj ntawm cov tshuaj yuav tsum tsis pub tshaj 10 mg / hnub.

Pharmacological kev txiav txim

Rosuvastatin Canon - cov tshuaj lipid-txo qis, xaiv sib tw inhibitor ntawm HMG-CoA reductase. Ua tau zoo rau cov neeg mob cov neeg mob hypercholesterolemia, nrog lossis tsis muaj hypertriglyceridemia (tsis hais haiv neeg, poj niam lossis txiv neej), suav nrog cov neeg mob ntshav qab zib mellitus thiab tsev neeg hypercholesterolemia.

Ib qho txiaj ntsig zoo ntxiv tau pom nrog kev sib xyaw nrog fenofibrate (hauv kev sib txuas nrog qhov kev txo qis ntawm cov concentration ntawm TG) thiab nicotinic acid nyob rau hauv lipid txo cov koob tshuaj (hauv kev sib piv rau qhov kev txo qis hauv cov concentration ntawm HDL-C).

Pheej yig analogues thiab hloov chaw rau cov tshuaj rosuvastatin: daim ntawv teev nqi

Rosuvastatin yog cov tshuaj siv nrov hauv kev kho mob ntawm cov kab mob ntawm cov hlab plawv.Lub cuab yeej normalizes cholesterol nyob rau hauv lub cev thiab txo qhov kev pheej hmoo ntawm kab mob plawv. Kev taw qhia rau kev noj tshuaj muaj xws li txhua yam mob hypercholesterolemia, sib xyaw dyslipidemia, atherosclerosis, myocardial infarction, paj hlwb, mob hlab ntsha tawg.

Cov tshuaj nquag siv ntawm cov tshuaj no ntawm tib lub npe nrog nws lub npe yog rosuvastatin. Qhov no yog tus neeg saib xyuas hypolipidemic los ntawm pab pawg ntawm satins. Daim ntawv tso tawm - ntsiav tshuaj. Cov tshuaj tsis tau sau tseg rau cov menyuam yaus hnub nyoog qis dua 18 xyoo, thaum cev xeeb tub, thaum lactation. Rosuvastatin yog tsim nyob rau hauv Russia, zoo li hauv qee lub tebchaws CIS thiab txawv teb chaws.

Tus nqi nruab nrab ntawm cov tshuaj yog 500-700 rubles, nyob ntawm seb qhov ntau npaum thiab pes tsawg ntawm cov ntsiav tshuaj hauv pob. Tus nqi siab ntawm cov tshuaj yuav tsum tau nrhiav qhov hloov pauv rau cov tshuaj pheej yig. Kaw cov kev hloov pauv thiab cov ntsiab lus tsis yog ib txwm pheej yig dua, tab sis qee qhov tsis muaj qhov zoo sib xws lossis muaj ntau dua hauv thaj chaw tshwj xeeb.

Yog tias tus kws kho mob tau sau ntawv tshaj tawm rosuvastatin, cov tshuaj analogues yuav pheej yig dua li cov tshuaj no yuav tsum pom ntawm cov tshuaj los ntawm cov chaw tsim khoom hauv lub tebchaws.

Lub npe ntawm cov tshuaj	Tus nqi nruab nrab hauv rubles	Ntseg
Akorta	550–880	Cov tshuaj yog tawm rau thawj hypercholesterolemia raws li Fredricksen, hyperglyceridemia, kom qeeb kev txhim kho ntawm atherosclerosis, tiv thaiv kev txhim kho ntawm cov kab mob plawv.
Mertenil	450–1750	Cov tshuaj yog tawm rau cov kab mob dyslipidemic, nrog hypercholesterolemia. Kev noj tshuaj yuav tsum tau ua ke nrog cov qauv kev noj haus zoo. Cov ntsiav tshuaj tau noj ntawm qhov ncauj, tsis hais txog ntawm cov khoom noj, ntxuav nrog dej.
Rosuvastatin Canon	400–710	Kev lipid-txo qis ua kom zoo ntawm cov tshuaj yog kom txo qis roj tag nrho. Qhov zoo tshaj plaws pheej yig analogue ntawm Lavxias teb sab.

Ukrainian hloov pauv

Xav txog pheej yig analogues ntawm cov tshuaj Ukrainian ntau lawm. Cov npe muaj cov kwv yees tus nqi thiab cov lus qhia luv luv ntawm kev siv tshuaj.

Cov AtorvacorCov. Ntsiav tshuaj nrog atorvastatin ua cov khoom xyaw dhia. Nws ua txoj haujlwm ntawm kev txhawm rau txo qib roj thiab lipoprotein hauv cov ntshav ntshav, ua nws cov haujlwm hauv cov neeg mob siab. Nws yog qhov ua tau kom muab tshuaj rau cov menyuam yaus tom qab 10 lub caij ntuj sov nrog tsev neeg heterozygous hypercholesterolemia yog ib qho ntxiv rau cov zaub mov tseem ceeb. Tus nqi nruab nrab yog 140-220 rubles.
VasostatCov. Kev siv tshuaj lipid-txo qis, cov tshuaj nquag yog simvastatin, uas zoo cuam tshuam rau lipid metabolism hauv lub cev. Siv cov tshuaj ntawm qhov ncauj. Teem sij hawm yog contraindicated nyob rau hauv cov ntaub ntawv ntawm daim siab tsis ua hauj lwm. Tus nqi nruab nrab yog 110-180 rubles.
LovastatinCov. Cov cuab yeej tshem tawm hyperlipoproteinemia, pab kom normalize roj synthesis hauv tus neeg mob lub siab. Cov tshuaj kuj txo apolipoprotein B thiab triglycerides. Cov nyhuv ruaj khov ntawm txoj kev kho nrog cov tshuaj tshwm sim 14 hnub tom qab pib noj cov ntsiav tshuaj. Lub ntsiab tivthaiv yog lovastatin. Nws tsis raug xaj thaum cev xeeb tub thiab lactation. Tus nqi nruab nrab yog 155-70 rubles rau pob ntawm 30 ntsiav tshuaj.

Belarusian generics

Cov lus hauv qab no muaj cov nqi pheej yig Belarusian generics ntawm rosuvastatin, uas yuav pab daws qhov teeb meem ntawm dab tsi los hloov cov tshuaj nrog.

Lub npe ntawm cov tshuaj	Tus nqi nruab nrab hauv rubles	Ntseg
Rosutatin	210–550	Cov tshuaj yog hauv cov ntsiav tshuaj nrog rosuvastatin yog cov tshuaj ntxiv. Nws muaj kev ntsuas rau kev siv zoo ib yam li tus neeg kuaj xyuas. Cov tshuaj muaj ib tug xov tooj ntawm contraindications.
Atorvastatin	120–600	Qhov pheej yig tshaj plaws hloov rau rosuvastatin. Cov cuab yeej yog koom nrog pab pawg ntawm pharmacological ntawm lipid-txo cov tshuaj thiab tau sau tseg rau hauv kev kho mob ntawm cov xwm txheej cuam tshuam nrog cov roj (cholesterol) ntau ntxiv. Cov tshuaj tsis tau teev tseg thaum cev xeeb tub, lactation, nrog rau cov menyuam yaus hnub nyoog qis dua 18 xyoo.
Lipromak LF	135–550	Cov tshuaj nquag hauv cov tshuaj yog atorvastatin. Txo cov ntshav lipoprotein ntau ntau. Cov tshuaj noj tau nthuav dav kev ua si hauv tus neeg mob lub siab, vim nws nyob ntawm no tias qhov tshuaj lom cov roj (cholesterol) tshwm sim tau tshwm sim.Siv nyob rau hauv cov menyuam yaus yog qhov ua tau nyob rau hauv qhov ntau npaum ntawm tsis ntau tshaj 20 mg.

Lwm cov lus piv txwv txawv teb chaws

Cov ntsiab lus ntshuam ntshuam niaj hnub yog ntawm tus nqi siab thiab tsis muaj tsawg dua tus nqi:

Neeg CoobCov. Txawv teb chaws analogue ntawm rosuvastatin, muaj nyob hauv ntsiav tshuaj. Ib qho tshuaj muaj roj lipid nrov. Cov tshuaj no yog tsim nyob hauv UK, Puerto Rico. Tus nqi nruab nrab yog 515-5900 rubles.
MertenilCov. Cov tshuaj muaj pes tsawg leeg suav nrog rosuvastatin yog cov tshuaj ua kom nquag. Txo lub xeev ntawm kev muaj zog ntawm cov cholesterol nyob rau hauv lub cev. Lub teb chaws ntawm hauv paus chiv keeb - Hungary. Tus nqi nruab nrab yog 510-1700 rubles.
RosistarkCov. Cov tshuaj noj los ntawm pawg pharmacological ntawm satins. Nws yog siv los kho hypercholesterolemia hauv cov neeg laus cov neeg laus dua 18 xyoo. Muaj nyob rau hauv Croatia. Tus nqi nruab nrab yog 250-790 rubles.

Txhua hom rosuvastatin, nrog rau nws cov analogues thiab cov kev hloov pauv uas muaj feem cuam tshuam, tau sawv cev rau hauv cov chaw muag tshuaj hauv cov nroog Lavxias.

Yuav tsum xyuam ximuas, tau txiav txim siab nyob rau hauv kev pom zoo ntawm ib hom tshuaj tshwj xeeb, nws yuav tsum tau noj tsis tu ncua, tsis tso cai hloov lwm yam tshuaj. Tias yog vim li cas qhov kev teem caij kawg yuav tsum tau ua los ntawm tus kws kho mob uas tsim nyog uas muaj peev xwm soj ntsuam kev pheej hmoo thiab cov kev mob tshwm sim.

Rosuvastatin Canon ntsiav tshuaj: cov lus qhia thiab cov qauv ntawm 10 thiab 20 mg

Rosuvastatin Canon yog yeeb tshuaj nrog lipid-txo cov khoom. Cov tshuaj yog zwm rau pab pawg neeg ntawm statins.

Cov tshuaj yog xaiv cov kev sib tw tshwj xeeb ntawm HMG-CoA reductase, uas yog lub luag haujlwm rau kev hloov pauv ntawm 3-hydroxy-3-methylglutaryl coenzyme A rau mevalonate, uas yog lub zog ua ntej ntawm cov roj (cholesterol).

Lub hom phiaj tseem ceeb ntawm kev siv yeeb tshuaj yog daim siab, ib qho khoom hauv nruab nrog cev uas ua cov txheej txheem ntawm cov roj (synthesis) thiab cov catabolism uas tsis muaj cov lipoproteins tsawg.

Cov tshuaj inhibits cov haujlwm ntawm HMG-CoA reductase. Thaum siv cov tshuaj, kwv yees li 90% ntawm rosuvastatin yob hauv cov ntshav ntshav.

Kev siv tshuaj yaj yeeb pab ua rau muaj ntau qhov LDL receptors nyob rau saum npoo ntawm hepatocytes, uas ua rau kev ntes ntau dua thiab catabolism ntawm lipoproteins tsawg ntom. Xws li cov nyhuv ntawm lub cev ua rau txo qis ntawm LDL hauv cov ntshav.

Kev kho kom zoo ntawm kev siv tshuaj yog pom muaj ib lim piam tom qab pib kho. Tom qab 2 lub lim piam, cov nyhuv kho tau mus txog nws qhov siab tshaj plaws. Tom qab lub sijhawm no, qhov zoo tshaj plaws nyob rau hauv qib hauv cov roj (cholesterol) hauv lub cev raug soj ntsuam thiab nrog kev siv cov tshuaj txuas ntxiv tas mus li nws tau tswj cov qib tiav nyob rau lub sijhawm ntev.

Kev siv cov tshuaj tuaj yeem pab txhawb nqa kom yuag vim qhov kev tshem tawm cov lipids ntau heev ntawm nws.

Tso daim ntawv thiab tshuaj lom neeg

Cov chaw tsim khoom tsim cov tshuaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj. Qhov saum npoo ntawm cov ntsiav tshuaj yog coated nrog cov xim pleev xim txheej xim.

Cov duab yog puag ncig, biconvex. Ntawm lub convex nto, kev pheej hmoo yog mob. Ntawm ntu Hla, npaj muaj xim yuav luag dawb.

Lub ntsiab ua haujlwm tseem ceeb hauv cov tshuaj yog rauvastatin calcium. Qhov sib xyaw ua ke no muaj nyob hauv huab hwm coj sib npaug nrog 10.4 mg, uas nyob rau hauv cov nqe lus ntawm rosuvastatin ntshiab yog 10 mg.

Ntxiv nrog rau lub ntsiab nquag compound, cov tshuaj sib txuas hauv qab no yog tam sim no hauv cov ntsiav tshuaj tsim:

calcium hydrogen phosphate dihydrate,
pregelatinized pob kws hmoov txhuv nplej siab,
magnesium stearate,
povidone
microcrystalline cellulose.

Qhov muaj pes tsawg leeg ntawm cov zaj duab xis txheej ntawm cov ntsiav tshuaj suav nrog cov khoom hauv qab no:

Selecoat AQ-01032 liab.
Hydroxypropyl methylcellulose.
Macrogol-400.
Macrogol-6000.
Titanium dioxide
Cov kua roj vanish raws cov xim Ponso 4R.

Cov chaw tsim khoom lag luam, cov ntsiav tshuaj tsim, chaw tso rau ntawm contour cellular ntim ntawm PVC. On to top ntawm lub pob yog them nrog txhuas ntawv ci.Cov pob khoom no tau muab ntim rau hauv cov thawv ntawv thawv, qhov twg cov lus qhia rau kev siv tshuaj raug tso rau.

Cov tshuaj muaj nyob rau hauv cov ntsiav tshuaj nrog ntau qhov sib txawv ntawm cov tshuaj nquag. Hauv cov khw muag tshuaj, nyob ntawm qhov xav tau, koj tuaj yeem yuav cov tshuaj uas muaj tshuaj rauvastatin 10, 20 thiab 40 mg hauv ib ntsiav tshuaj.

Tus nqi ntawm cov tshuaj yog nyob ntawm thaj av ntawm kev muag khoom hauv Lavxias teb sab, kev saib xyuas cov khoom tseem ceeb hauv cov tshuaj muaj pes tsawg leeg thiab pes tsawg ntsiav tshuaj hauv ib pob.

Tus nqi ntawm ib pob, nyob ntawm qhov ntsuas tshwj xeeb, tuaj yeem muaj li ntawm 350 txog 850 rubles.

Tus neeg mob tuaj yeem yuav cov tshuaj tsuas yog muaj daim ntawv tshuaj ntawm tus kws kho mob uas tuaj koom.

Cov tshuaj yuav tsum khaws cia ntawm qhov kub thiab txias tsis tshaj 25 degrees Celsius hauv qhov chaw tsis zoo rau me nyuam yaus thiab tsiaj. Qhov chaw khaws cia yuav tsum muaj kev tiv thaiv los ntawm tshav ntuj ncaj qha. Lub txee lub neej ntawm cov tshuaj yog ob xyoos.

Tom qab lub sijhawm no, kev siv tshuaj yog txwv, nws yuav tsum tau muab pov tseg.

Kev taw qhia thiab contraindications rau siv

Ua ntej siv cov tshuaj Rosuvastatin Canon, koj yuav tsum ua tib zoo kawm cov lus qhia rau kev siv, tshuaj xyuas txog kev siv tshuaj ntawm cov kws kho mob thiab cov neeg mob, thiab paub koj tus kheej kom paub tus nqi ntawm cov tshuaj nrog ntau npaum li cas ntawm cov tshuaj nquag nquag.

Kev taw qhia txog kev siv tshuaj pom zoo kom noj tshuaj tsuas yog tom qab sab laj nrog koj tus kws kho mob.

Tus kws kho mob txiav txim siab qhov zoo tshaj plaws, noj mus rau hauv tus account tag nrho cov ntaub ntawv hais txog kev noj qab haus huv thiab tus cwj pwm ntawm tus neeg mob lub cev.

Cov cim tseem ceeb rau kev siv cov tshuaj raws li cov lus qhia rau kev siv yog cov xwm txheej hauv qab no:

muaj cov thawj hypercholesterolemia raws li Fredrickson (hom IIa, suav nrog rau kev mob heterozygous hypercholesterolemia) lossis sib xyaw hypercholesterolemia (hom IIb) raws li kev pabcuam rau kev noj zaub mov, nyob rau hauv cov xwm txheej ntawm kev siv tshuaj tsis-pharmacological (kev tawm dag zog lub cev, poob phaus) tsis txaus,
muaj cov tsev neeg homozygous hypercholesterolemia, ntxiv rau kev noj zaub mov noj thiab lwm txoj kev kho lipid-piv txwv (piv txwv li, LDL-apheresis), lossis nyob rau hauv rooj plaub uas siv cov kev kho mob ntawd tsis muaj txiaj ntsig txaus,
muaj cov hypertriglyceridemia (hom IV raws li Fredrickson) yog ib qho ntxiv rau kev noj haus uas siv.

Txoj hauv kev siv lub zog muaj ntau yam sib txawv nyob ntawm kev saib xyuas hauv cov ntsiav tshuaj ntawm lub zog tseem ceeb.

Yog li rau cov ntsiav tshuaj uas muaj 10 thiab 20 mg ntawm rosuvastatin, tus neeg mob muaj cov kab mob hauv qab no:

Cov kab mob siab nyob rau theem nquag kev vam meej, suav nrog kev ua haujlwm transaminase nce.
Kev ua tsis zoo rau lub raum kev ua haujlwm.
Qhov kuaj pom myopathy hauv tus neeg mob.
Kev siv ntawm kev kho cyclosporin.
Lub sijhawm ua haujlwm tiav thiab lub sijhawm lactation.
Kev cog lus rau kev hloov zuj zus ntawm myotoxic teeb meem.
Hnub nyoog qis dua 18 xyoo.
Hypersensitivity rau lub Cheebtsam ntawm cov tshuaj.

Thaum siv cov ntsiav tshuaj nrog kev saib xyuas ntawm rosuvastatin 40 mg, contraindications rau kev siv yog:

lub raum thiab lub siab ua haujlwm,
nqa tus me nyuam thiab pub niam mis,
siv cov khoom xa hluav taws xob nrog cyclosporine,
muaj qhov mob ntawm daim siab mob nyob rau hauv cov theem mob ntawm kev loj hlob,
muaj nyob rau hauv lub cev ntawm kev hais tawm rau hauv Cheebtsam ntawm cov tshuaj.

Kev noj tshuaj ntau dhau ntawm ib tus neeg mob tshwm sim thaum siv tshuaj ntau ntau txhua hnub.

Yog tias pom muaj ib qho kev noj ntau dhau, kev kho mob txoj kev kho yog raug tso tseg thiab lub siab ua haujlwm, nrog rau CPK kev ua si, yuav saib xyuas.

Tsis muaj ib qho tshuaj tua kab mob tshwj xeeb siv thaum muaj kev noj ntau dhau tshwm sim. Tus txheej txheem hemodialysis ua tsis tau zoo.

Cov lus qhia rau kev siv tshuaj

Cov tshuaj yog muab ntawm qhov ncauj, thaum lub sijhawm thaum nruab hnub, tsis hais noj zaub mov noj.

Cov ntsiav tshuaj yuav tsum nqos tag nrho yam tsis muaj kev zuaj, thaum noj cov khoom yuav tsum nrog kev haus dej ntau.

Thaum lub sijhawm teem ntawm cov tshuaj nyob rau hauv ib txoj kev siv ntawm 5 mg, ib ntsiav tshuaj nrog qhov loj ntawm qhov kev ua haujlwm ntawm 10 mg yuav muab faib ua ib nrab.

Ua ntej ua kev kho mob nrog Rosuvastatin, Canon yuav tsum kom tus neeg mob tswj hwm kev noj qab haus huv hypocholesterol nyob rau qee lub sijhawm. Ua raws li kev noj haus zoo li no kuj yuav tsum tom qab pib noj tshuaj.

Cov koob tshuaj ntawm cov ntsiav tshuaj rau cov roj (cholesterol) yog xaiv los ntawm tus kws kho mob koom nrog saib xyuas qhov txiaj ntsig ntawm kev tshuaj ntsuam thiab kev tshawb fawb ntawm tus neeg mob lub cev tom qab thov cov zaub mov noj thiab nws tus yam ntxwv.

Tsis tas li ntawd, ntau npaum li cas ntawm cov tshuaj uas siv yuav raug cuam tshuam los ntawm lub hom phiaj kho thiab qhov xwm ntawm lub cev teb rau kev siv Canon hauv kev kho Rosuvastatin.

Ua raws li cov lus qhia rau kev siv, kev pom zoo pom zoo thawj zaug ntawm cov tshuaj yog 5 lossis 10 mg ib hnub ib zaug.

Nrog rau kev siv rosuvastatin sib xyaw nrog fibrates lossis nicotinic acid hauv kev siv tshuaj ntau dua tsis pub tshaj 1 gram ib hnub, thawj koob tshuaj yog 5 mg ib hnub ib zaug.

Thaum xaiv cov koob tshuaj, tus kws kho mob yuav tsum tau ua raws li cov txiaj ntsig los ntawm kev ntsuas tus nqi hauv cov roj (cholesterol) hauv tus neeg mob lub cev thiab coj mus rau hauv qhov kev pheej hmoo ntawm kev muaj peev xwm ntawm kev mob plawv. Ntxiv rau, tus kws kho mob tshwj xeeb yuav tsum coj mus rau hauv qhov kev pheej hmoo ntawm kev mob tshwm sim los ntawm kev siv tshuaj hauv cov chav kho mob.

Yog tias tsim nyog, qhov ntau ntawm cov tshuaj uas siv tau raug hloov kho txhua 4 asthiv.

Kev siv tshuaj ntawm 40 mg yog tsuas yog ua rau cov neeg mob uas muaj kev loj hlob los ntawm kev loj hlob ntawm hypercholesterolemia thiab nyob rau ntawm qhov kev pheej hmoo siab ntawm cov teeb meem hauv kev ua haujlwm ntawm cov hlab plawv ntawm lub cev, nrog rau kev tshawb pom ntawm cov ntshav siab hauv tus neeg mob. Kev siv ntau tshaj qhov tau tso cai siv thaum kho mob, tus neeg mob yuav tsum nyob hauv qab kev saib xyuas tas mus li ntawm cov kws kho mob koom.

Kev siv cov tshuaj nyob rau hauv cov tshuaj ntau tshaj yog contraindicated nyob rau hauv cov neeg mob uas tshaj tawm lub raum tsis ua hauj lwm thiab mob raum.

Rau pawg no ntawm cov neeg mob, qhov pom zoo koob tshuaj yog 5 mg rau ib hnub nyob rau hauv ib koob.

Kev phiv tshuaj thiab analogues ntawm Rosuvastatin Canon

Hauv kev siv tshuaj, cov kev mob tshwm sim tuaj yeem tsim kho hauv tus neeg mob lub cev.

Qhov ntau zaus ntawm cov kev mob tshwm sim nyob ntawm kev siv ntau npaum li cas thiab cov tib neeg muaj sia ntawm yam ntxwv ntawm tus neeg mob.

Los ntawm sab nruab nrab ntawm lub hauv nruab nrab lub paj hlwb, mob taub hau, kiv taub hau thiab, muaj qee zaus, tsis nco qab yuav tshwm sim.

Los ntawm qhov mob tshwm sim ntawm txoj hnyuv txhaws tshwm sim los ntawm cov tsos mob ua kom tawv ncauj, xeev siab, mob plab, muaj qee zaus, muaj kev txhim kho ntawm pancreatitis thiab jaundice.

Lub tshuab ua pa tuaj yeem teb rau cov tshuaj nrog cov kev pom zoo li hnoos thiab txog siav.

Los ntawm cov leeg musculoskeletal, cov tsos ntawm myalgia yog ua tau. Myopathies thiab, Muaj qee zaus, mob arthralgia.

Ntawm ib feem ntawm cov mob txeeb zig, cov tshuaj tiv thaiv ib sab tuaj yeem tshwm sim nyob rau hauv daim ntawv ntawm proteinuria, peripheral edema thiab, muaj qee zaus, hematuria.

Raws li kev noj tshuaj, tus neeg mob yuav muaj cov tsos mob ntawm tus mob ntshav qab zib hom 2.

Yog tias muaj kev cuam tshuam rau lub cev los ntawm kev noj tshuaj pom, nws tuaj yeem hloov los ntawm kev pom zoo ntawm tus kws kho mob koom nrog cov analogues uas twb muaj lawm.

Txog rau tam sim no, cov chaw tsim tshuaj lag luam muaj ntau dua 10 yam tshuaj uas sib piv ntawm Rosuvastatin Canon.

Cov cuab yeej no yog:

Akorta,
Mertenil.
Hlua.
Rosistark.
Rosuvastatin Sotex.
Rosuvastatin SZ.
Rosulip.
Rosucard.
Kwv Txhiaj Ntsuag.
Xeb.
Tevastor

Tag nrho cov tshuaj no muaj qhov zoo sib xws rau ntawm lub cev, tab sis muaj qhov sib txawv ntawm cov nqi, uas tso cai rau tus neeg mob xaiv cov kev kho mob uas zoo tshaj plaws, ob qho tib si hauv tus nqi thiab cov txiaj ntsig kho hauv lub cev.

Cov tshuaj Rosuvastatin tau piav qhia hauv cov yeeb yaj kiab hauv tsab xov xwm no.

Qhia koj qab zib lossis xaiv tus tub los ntxhais rau cov lus pom zoo Nrhiav. Nrhiav tsis pom. Tshawb pom. Nrhiav tsis pom. Pom. Nrhiav tsis pom.

Rosuvastatin: analogues thiab cov nqi

Feem ntau, rosuvastatin yog cov tshuaj ntawm cov kev xaiv thaum nws yog qhov yuav tsum tau muab cov tshuaj lipid-txo qis. Txawm li cas los xij, tej zaum yuav muaj qee qhov laj thawj thaum tus neeg mob muaj teeb meem los yuav yam tshuaj no:

Tsis muaj tshuaj nyob hauv cov tsev muag tshuaj hauv zos.
Txaus tus nqi siab ntawm cov tshuaj, uas yuav cuam tshuam rau tus neeg mob cov nyiaj txiag, txij li kom ua tiav cov txiaj ntsig kho qhov xav tau, daim ntawv thov kev kawm yog qhov tsim nyog.

Feem ntau cov tshuaj muaj analogues. Thiab "Rosuvastatin", raws li cov tshuaj ntawm qhov xav tau siab, hauv qhov no, tsis muaj qhov zam.

Cov tshuaj Analog yog cov tshuaj uas zoo ib yam rau hauv cov tshuaj qub, tab sis uas yog tsim los ntawm cov tuam txhab kws kho mob uas tsis yog cov tsim tawm qub.

Hauv lwm lo lus, Rozuvastatin analogues ntawm lub khw muag tshuaj yog tag nrho cov tshuaj uas nws cov khoom xyaw yog rosuvastatin, tab sis lawv yog tsim los ntawm lub tuam txhab uas tsis yog tuam txhab Japanese Shionogi.

Nws yog tsim nyog sau cia tias cov neeg tshaj lij ntawm cov tuam txhab sib txawv ntawm Rosuvastatin tuaj yeem sib txawv, uas tsis cuam tshuam nrog kev kho mob, tab sis yuav tsum raug coj mus rau hauv tus neeg mob tsis zoo rau qee yam.

Hauv qab no yog cov npe ntawm cov analogues tseem ceeb ntawm Rosuvastatin, uas, yog tias tsim nyog, tuaj yeem hloov cov tshuaj qub. Thiab kuj yog qhov sib piv cov lus ntawm cov nqi ntawm rosuvastatin ntawm ntau cov tuam ntxhab yuav raug nthuav tawm. Tab sis ua ntej, koj yuav tsum muab cov lus qhia luv luv txog cov khoom qub, kom cov neeg siv khoom tau sib piv cov yam ntxwv txawv tshwj xeeb tshaj yog cov khoom qub thiab cov qub.

Cov muaj pes tsawg leeg ntawm "Rosuvastatin"

Rosuvastatin yog ib cov tshuaj los ntawm cov pab pawg ntau kawg ntawm cov tshuaj lipid-txo cov tshuaj, uas yog pawg ntawm ib qho kev cais kom tsawg ntawm reductase inhibitors (nquag tiv thaiv cov roj cholesterol). Tus nquag ua khoom noj yog rosuvastatin nyob rau hauv daim ntawv ntawm calcium calcium (i.e.: Calcium rosuvastatin). Ua tiav cov npe ntawm kev xa tawm ntawm cov thawj cov ntsiav tshuaj:

Lactose monohydrate yog suab thaj mis uas txawv ntawm lactose zoo tib yam los ntawm qhov pom tias muaj cov dej ntxiv nyob rau hauv cov tshuaj lom neeg. Qhov muaj cov khoom tiv thaiv no ua rau rosuvastatin nkag tsis tau rau cov neeg mob nrog tus neeg tsis haum lactose, lossis nrog lactase tsis txaus.
MCC yog microcrystalline cellulose, uas yog lub zog nqus uas tsis yog nqus los ntawm tib neeg lub cev. Nws nqus cov co toxins thiab lwm yam tshuaj phem thiab tom qab ntawd tshem tawm lawv ntawm lub cev hauv daim ntawv hloov pauv, uas yog, nws pab txo qis slagging ntawm lub cev. Mob siv rau kev lom thiab tsis txaus ntawm cov hnyuv thiab lub plab. Tus naj npawb ntawm cov khoom noj khoom haus tau pom zoo kom siv los ua txoj hauv kev txo kev qab los noj mov, txij li MSC muab txoj kev xav ntawm tag nrho ntawm lub plab.
Orthophosphate (calcium phosphate) - yog cov ntsev ua nyuaj uas muaj cov orthophosphoric acid thiab calcium hlau. Nws muaj cov hmoov ua cov haujlwm thiab txhawb nqa kom zoo dua rosuvastatin.
Magnesium stearate - yog cov ntsev ua nyuaj uas muaj stearic acid thiab magnesium. Nws yog tib neeg lub siab nyiam ua ke rau cov khoom lag luam pharmacological, uas nws tau tas li tsis hloov pauv ntawm lub cev.
Crospovidone (kev sau ntawv yuav tshwm sim: povidone, uas yog lwm lub npe hloov) yog qhov dav-spectrum enterosorbent. Nws muaj peev xwm los nqus cov teeb meem hauv lub cev (suav nrog cov uas tsim los ntawm kev ua ntawm rosuvastatin ntawm tib neeg lub cev).
Glyceryl triacetate (triacetin) yog zaub mov ntxiv rau daim ntawv lo E1518, raug tso cai nyob hauv ntau lub teb chaws hauv ntiaj teb (tshwj xeeb, hauv Lavxias Federation thiab cov teb chaws ntawm Tebchaws Europe) thiab, raws li kev tshawb fawb ntau, tau pom tias muaj kev nyab xeeb rau tib neeg lub cev. Hauv kev tsim cov khoom lag luam tshuaj muaj cov khoom siv dhau los ua cov tshuaj noo, tshuab ua kom sov thiab cov kuab tshuaj.
Hypromellose (Hydroxypropyl methylcellulose) - muaj cov khoom tiv thaiv cov tawv nqaij noo.
Cov hlau oxide - yog ib yam khoom uas muaj keeb kwm inorganic, uas muaj hlau thiab oxygen. Raws li ib feem ntawm "Rosuvastatin" nws yog siv los ua zas xim.
Titanium dioxide (cov khoom hauv qab no kuj tseem tuaj yeem pom: titanium oxide IV, titanium dawb) - xim zaub mov nrog cim npav E
Lim dej.

Vim li cas koj xav paub txog cov analogues ntawm "Rosuvastatin"

Lub peev xwm los yuav cov tshuaj nyob ntawm tus nqi zoo tshaj plaws. Feem ntau, cov analogues muaj cov nqi qis dua. Qhov no tsis hais txog qhov zoo ntawm cov khoom, tab sis tej zaum yuav yog vim txo qis ntawm kev tshaj tawm, kev thauj mus los thiab lwm yam nqi. Tsis tas li, cov xwm txheej ntawm kev sib koom tes ntawm kev kho mob tshwj xeeb lossis chaw kho mob nrog cov tuam txhab muag tshuaj lossis cov khw muag tshuaj tsis txawv txav, thaum ib daim tseem kim lossis cov ntawv qub qub tuaj yeem sau rau tus neeg mob.
Lub caij nyoog ntawm qhov hloov rosuvastatin thaum tsis muaj tus thawj cov tshuaj hauv lub tsev muag tshuaj. Feem ntau, txawm tias tus kws muag tshuaj tsis tuaj yeem qhia tshuaj analogues ntawm cov tshuaj, lossis sim muag cov tshuaj uas kim tshaj plaws.

Daim ntawv teev cov analogues ntawm "Rosuvastatin"

Lub npe ntawm cov tshuaj Siv Cov Khoom Taw Qhia Cov yam ntxwv sib txawv ntawm kev siv, thiab lwm yam

Neeg Coob	ASTRAZENECA UK LTD (Tebchaws Asmeskas).	lactose monohydrate, mcc, magnesium stearate, calcium hydrogen phosphate, iron oxide, hypromellose, titanium dioxide, crospovidone	yog tsis tuaj
Akorta	PJSC Pharmstandard-Tomskkhimfarm (Lavxias teb sab)	tib yam li tus "Crestor"	yog tsis tuaj
Mertenil	Gedeon Richter (Hungary)	tib yam li tus "Crestor"	cov ntsiav tshuaj nrog tshaj tawm cov ntawv tshaj tawm muaj 0.2 mg ntau dua ntawm rosuvastatin rau txhua 5 mg, uas yog: ntsiav tshuaj ntawm 5 mg - qhov tseeb cov ntsiab lus ntawm rosuvastatin yog 5.2 mg, hauv cov ntsiav tshuaj ntawm 10 mg - 10.4 mg thiab lwm yam.
Hlua	Cov Pawg Actavis (Iceland)	tib yam li tus "Crestor"
Rosistark	Belupo (Croatia)	quinoline daj yog siv los hloov cov hlau oxide, lwm yam khoom zoo ib yam
Rosuvastatin calcium	MSN Lub Chaw Ntsuas Muaj Zog (Is Nrias teb), Assia Chemical Industries Ltd (Israel) thiab lwm yam	yog tsis tuaj	cov tshuaj tsis raug muag los ntawm cov khw muag tshuaj saw muag, qhov yuav tsawg kawg yog feem ntau los ntawm 5 kg.
Rosuvastatin Canon	Cov Chaw Haujlwm Tsis Siv Nyiaj Canonfarm Ntau Lawm	es tsis txhob siv cov hlau oxide, cov kua roj vanish siv thiab liab selecoate ntxiv, lwm cov khoom xyaw zoo ib yam li cov qauv txheem	ntau qhov kev tshuaj xyuas zoo
Rosuvastatin-SZ	Lub tuam txhab Pharmacological "North Star"	hlau oxide tseem hloov los ntawm cov kua roj vanish ntawm peb ntau yam	yog tsis tuaj
Rosucard	Zentiva (Czech koom pheej)	croscarmellose hloov hypromellose los ntawm cov thawj muaj pes tsawg leeg, lwm cov khoom siv tsis zoo ib yam
Rosulip	EGIS Pharmaceuticals PLC (Hungary)	zoo tib yam rau cov thawj muaj pes tsawg leeg
Kwv Txhiaj Ntsuag	KRKA (Slovenia)	copolymer ntawm butyl methacrylate thiab methyl methacrylate tau ntxiv rau lub plhaub
Tevastor	"TEVA Pharmaceutical Industries, Ltd" (Ixayees)	Cov pes tsawg leeg suav nrog cov kua roj vanish thiab cov xim ziab tshav ntuj daj, cov khoom sib txuas ntxiv zoo ib yam rau thawj cov qauv (suav nrog hlau oxide)

Tag nrho cov tshuaj saum toj no yog qhov ncaj qha ntawm rosuvastatin, uas yog, tshuaj nrog cov tshuaj muaj zog zoo ib yam. Qhov tseeb, qhov no yog txhua yam - tib cov yeeb tshuaj nrog cov lag luam txawv npe thiab muag ntawm tus nqi muag khoom txawv thiab muag khoom (tus nqi nruab nrab yuav muab rau hauv lub rooj hauv ntu txuas ntxiv ntawm kev tshaj tawm). Tseem muaj cov piv txwv tsis ncaj, uas yog, cov tshuaj los ntawm ib pawg pharmacological (hauv qhov no, reductase inhibitors) uas muaj cov nyhuv zoo sib xws, tab sis muaj cov tshuaj sib txawv. Cov tshuaj no yog cov tshuaj pov thawj tsis sib xws thiab tuaj yeem yog tus kws tshaj lij tshwj xeeb los ntawm cov kws tshaj lij nyob rau ntawm lub hauv paus ntawm cov ntaub ntawv kuaj.

Sib piv cov lus ntawm cov nqi ntawm analogues ntawm "Rosuvastatin"

Akorta	Nqe: 530 rubles
Mertenil	Nqe: 500 rubles
Hlua	Nqe: 485 rubles
Rosistark	Nqe: 450 rubles
Rosuvastatin Canon	Nqe: 420 rubles
Rosuvastatin-SZ	Nqe: 450 rubles
Rosucard	Nqe: 590 rubles
Rosulip	Nqe: 515 rubles
Kwv Txhiaj Ntsuag	Nqe: 540 rubles
Tevastor	Nqe: 480 rubles

Rau cov laj thawj ntawm txoj kev tshawb no, ua rau txoj kev nyiam ntawm cov neeg tau txais kev pab ntawm cov tshuaj hauv cov lus nug, cov npe saum toj no muaj cov tshuaj analogues hauv cov tshuaj hauv qab thiab cov ntau: 10 mg ntawm rosuvastatin rau ib ntsiav tshuaj, 30 ntsiav tshuaj hauv ib pob. Daim ntawv ntawm qhov kev siv no yog qhov nrov tshaj plaws ntawm cov neeg siv khoom, vim tias nws raug nquahu kom pib tswj hwm cov tshuaj hauv ib hlis ib hlis txhawm rau txiav txim siab qhov kev hloov kho ntawm tib neeg lub cev mus rau rosuvastatin.

Tus nqi ntawm "Rosuvastatin" thiab lub peev xwm ntawm hloov nws nrog analogues

Hauv cov khw muag tshuaj saw "Rosuvastatin" hauv qhov tshuaj ntawm 10 mg thiab tus naj npawb ntawm cov ntsiav tshuaj, 30 daim yog muag nyob rau hauv tus nqi ntau ntawm 380 txog 490 rubles, nyob ntawm txoj cai nqe ntawm tus neeg muag khoom thiab xa tawm ntawm cov tshuaj lag luam, nrog rau thaj tsam ntawd.

Yog li, feem ntau, qhov qub Rosuvastatin khoom yog qhov pheej yig dua li nws cov analogues, thiab nws raug nquahu kom yuav cov analogues nkaus xwb yog tias tsis muaj cov tshuaj tiv thaiv thawj hauv cov tshuaj no.

Raws li cov kev txheeb xyuas tshaj tawm nyob rau hauv qhov chaw pej xeem hauv Is Taws Nem thiab hauv xov xwm luam ntawv, nws tseem tuaj yeem xaus lus tias cov neeg siv khoom nyiam nyiam cov tshuaj qub.

Pom qhov yuam kev hauv cov ntawv nyeem? Xaiv nws thiab nias Ctrl + Sauthiab peb yuav kho nws!

Cov ntsiav tshuaj 5 mg, 10 mg, 20 mg thiab 40 mg Rosuvastatin: cov lus qhia, tshuaj xyuas thiab cov nqi

Hauv tsab xov xwm kho mob no, koj tuaj yeem paub txog cov tshuaj Rosuvastatin. Cov lus qhia rau kev siv yuav piav qhia txog ntawm cov ntsiav tshuaj siab yuav noj dab tsi, cov tshuaj pab nrog dab tsi, dab tsi qhia tau muaj rau siv, contraindications thiab phiv. Tus lej piav txog tus qauv ntawm cov tshuaj thiab nws muaj pes tsawg leeg.

Hauv tsab xov xwm, cov kws kho mob thiab cov neeg siv khoom tuaj yeem tawm tsuas yog kev txheeb xyuas tiag tiag txog Rosuvastatin, los ntawm qhov koj tuaj yeem tshawb pom seb cov tshuaj puas pab rau kev kho mob hypercholesterolemia thiab txo cov roj ntshav hauv cov neeg laus thiab menyuam yaus, uas nws tseem tau sau tseg. Cov lus qhia tau teev tseg cov qauv ntawm cov tshuaj Rosuvastatin, tus nqi ntawm cov tshuaj hauv cov khw muag tshuaj, nrog rau nws siv thaum cev xeeb tub.

Cov lipid-txo tshuaj yog rosuvastatin. Cov lus qhia rau kev siv qhia tau tias cov ntsiav tshuaj 5 mg, 10 mg, 20 mg thiab 40 mg roj ntshav qis, lawv tau raug kho rau kev kho mob hypercholesterolemia, zoo li rau kev tiv thaiv ntawm atherosclerosis.

Tso tawm daim ntawv thiab muaj pes tsawg leeg

Cov tshuaj Rosuvastatin yog tsim nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj, zaj duab xis-ntsiav tshuaj rau kev tswj hwm qhov ncauj (qhov ncauj).

Lawv muaj lub teeb xim liab lossis xim paj yeeb, puag ncig duab thiab thaj chaw biconvex.

Lub ntsiab tseem ceeb ntawm cov tshuaj yog rosuvastatin, nws cov ntsiab lus hauv 1 ntsiav tshuaj yog 5, 10, 20 lossis 40 mg.Tsis tas li, nws muaj pes tsawg leeg suav nrog cov neeg tshaj lij

Rosuvastatin ntsiav tshuaj tau ntim rau hauv blister pob ntawm 10 daim. Daim npav pob ntawv muaj 3 lossis 6 blister pob thiab cov lus qhia rau kev siv tshuaj.

Sab sij huam

Tawm tsam keeb kwm yav dhau los ntawm kev noj cov ntsiav tshuaj Rosuvastatin, kev txhim kho kev tsis zoo ntawm lub cev los ntawm ntau yam plab hnyuv siab raum thiab lub nruab nrog:

Ua xua - ua pob rau ntawm daim tawv nqaij, nws khaus khaus, khaus, zoo li kub hnyiab tawm.
Lub plab zom mov - ib qho nyiam ua rau cem quav, xeev siab, mob hauv plab, thiaj li tsis tshua mob txhaws tawm (tus mob hu ua "pancreatitis").
Tso zis hauv lub cev - tsis tshua pom cov protein (proteinuria) thiab ntshav (hematuria) hauv cov zis.
Endocrine system - kev txhim kho ntawm hom 2 mob ntshav qab zib.
Musculoskeletal system - mob leeg (myalgia), mob (myositis) thiab rhuav tshem (rhabdomyolysis), tshwj xeeb tshaj yog nyob rau hauv cov neeg muaj mob ua ntej rau myopathy.
Mob leeg - mob taub hau, tsis tu ncua, kiv taub hau, mob nkees heev (asthenia).

Kev txhim kho cov kev mob tshwm sim yog qhov siv tshuaj tiv thaiv kab mob tshwm sim. Lawv qhov kev hloov pauv nce ntau nrog kev siv tshuaj ntawm ib koob ntawm 40 mg ib hnub twg. Cov tsos mob ntawm kev tsis zoo yog lub hauv paus rau kev kho ntau npaum li cas lossis kev tshem yeeb tshuaj.

Cov menyuam yaus, thaum cev xeeb tub thiab lactation

Rosuvastatin yog contraindicated thaum cev xeeb tub thiab thaum pub niam mis. Cov poj niam ntawm kev muaj me nyuam hnub nyoog yuav tsum siv txoj kev ua kom muaj txiaj ntsig kom tsim nyog. Txij li cov roj (cholesterol) thiab nws cov khoom siv roj ntsha (biosynthesis) yog qhov tseem ceeb rau kev loj hlob ntawm tus menyuam, qhov kev pheej hmoo muaj peev xwm los tiv thaiv HMG-CoA reductase ntau dua li cov txiaj ntsig ntawm kev siv tshuaj hauv cov pojniam cev xeeb tub.

Yog tias cev xeeb tub thaum kho, cov tshuaj yuav tsum nres tam sim ntawd. Tsis muaj ntaub ntawv hais txog kev faib cov rosuvastatin nrog rau niam cov kua mis, yog li ntawd, thaum lub sijhawm pub niam mis, cov tshuaj yuav tsum tau tsum tsis ua ntxiv.

Cov lus qhia tshwj xeeb

Thaum siv cov koob tshuaj ntau dua ntawm rosuvastatin (feem ntau 40 mg), tubular proteinuria tuaj yeem pom, uas feem ntau yog hloov rau hauv xwm. Qhov kev ua txhaum no tsis yog qhia txog kev ua rau lub raum hnyav zuj zus.

Cov neeg mob noj ntau tshaj plaws ntawm cov tshuaj raug pom zoo kom saib xyuas lub raum ua haujlwm. Txhawm rau kom tsis txhob cuam tshuam ntawm cov txiaj ntsig, nws tsis pom zoo los txiav txim siab kev ua si ntawm creatine phosphokinase tom qab nce kev ua haujlwm hauv lub cev lossis muaj lwm qhov laj thawj uas ua rau muaj ntau ntxiv.

Yog tias thaum pib kho, qhov pib ua haujlwm ntawm creatine phosphokinase tau zoo tshaj (ntau tshaj 5 zaug), tom qab 5-7 hnub, ntsuas thib ob yuav tsum tau ua. Thaum paub tseeb tias qhov ntsuas, kev kho mob tsis pib. Qhov pib mob sai sai ntawm cov leeg mob / tsis muaj zog lossis mob plab, tshwj xeeb tshaj yog ua ke nrog kub taub hau thiab malaise, yuav tsum tau saib xyuas mob.

Hauv cov xwm txheej zoo li no, nws yog ib qho tsim nyog los txiav txim siab kev ua haujlwm ntawm creatine phosphokinase. Yog tias cov tsos mob ploj, thiab qhov ntsuas rov qab zoo li qub, koj tuaj yeem xav txog kev teem sijhawm rov qab los ntawm Rosuvastatin hauv kev noj tshuaj tsawg dua hauv kev saib xyuas tus neeg mob lub sijhawm. Thaum tsis muaj cov tsos mob, kev niaj hnub saib xyuas ntawm creatine phosphokinase kev ua ub no yog impractical.

Muaj pov thawj pom tias muaj tsawg kawg ntawm cov tshuaj tiv thaiv kab mob-tiv thaiv necrotizing myopathy tshwm sim nrog cov kev kuaj mob (cov leeg tsis muaj zog ntawm cov leeg tsis muaj zog thiab ua kom cov ntshav muaj zog ntau ntxiv) thaum kho lossis thaum Rosuvastatin tsis ua haujlwm ntxiv lawm. Tsis tas li ntawd, kev tshawb nrhiav serological, kev soj ntsuam cov leeg thiab cov leeg mob, nrog rau kev siv tshuaj tiv thaiv kab mob yuav tsum tau ua.

Thaum noj Rosuvastatin thiab concomitant kev kho, qhov cim ntawm kev cuam tshuam rau cov leeg pob txha tsis raug cai.

Txawm li cas los xij, muaj ntawv tshaj tawm txog kev nce ntxiv ntawm qhov tshwm sim ntawm myopathy thiab myositis nyob rau hauv cov neeg mob noj lwm qhov HMG-CoA reductase inhibitors muab tso ua ke nrog fibric acid derivatives, suav nrog

nrog gemfibrozil, cyclosporine, nicotinic acid nyob rau hauv lipid txo cov koob tshuaj (ntau tshaj 1000 mg ib hnub), azole antifungal tus neeg sawv cev, HIV protease inhibitors thiab tshuaj tua kab mob macrolide.

Yog hais tias nyob rau hauv cov neeg mob cov ntshav qabzib concentration qhia yog 5.6-6.9 mmol / L, qhov muaj peev xwm ntawm hom 2 mob ntshav qab zib mellitus nce. Kev txo qis / thim ntawm kev kho yog qhia nyob rau hauv cov xwm txheej uas qhov kev ua si ntawm hepatic transaminases hauv cov ntshav cov ntshav siab tshaj qhov txwv qis ntawm ib txwm los ntawm 3 zaug lossis ntau dua.

Yog tias muaj kev ua xyem xyav ntawm kev txhim kho cov kab mob ntsws interstitial ntsws (ua kom pom tias ua pa luv, ua pa hnoos tsis muaj zog, tsis muaj zog, poob phaus, ua npaws thiab paub zoo), Rosuvastatin tau muab tso tseg.

Vim tias qhov tshwm sim ntawm kev txhim kho tsis muaj zog thiab kiv taub hau, cov neeg mob yuav tsum tau ceev faj thaum lub sijhawm kho mob thaum tsav tsheb.

Yeeb tshuaj sib cuam tshuam

Cov tshuaj tiv thaiv kab mob tuaj yeem tsuas yog tom qab qee lub sijhawm (txog 2 teev) tom qab noj cov tshuaj no, vim tias lawv siv coj mus rau qhov txo qis ntawm cov tshuaj Rosuvastatin.

Erythromycin kuj yuav tsum tsis txhob noj nrog rau kev noj tshuaj, vim tias cov nyhuv ntawm kev noj tshuaj raug txo.

40 mg rosuvastatin nyob rau hauv txuas nrog fibrates yog contraindicated. Gemfibrozil tsub kom muaj kev pheej hmoo ntawm myopathy thaum siv ua ke nrog qee yam HMG-CoA reductase inhibitors (kev sib xyaw tsis pom zoo). Thaum ua ke nrog cov tshuaj fibrates lossis lipid-txo cov koob tshuaj nicotinic acid, qhov kev pheej hmoo yuav tsum ua tib zoo txiav txim siab.

Analogues ntawm cov tshuaj rosuvastatin

Tus qauv txiav txim siab pom cov qauv analogues:

Tevastor
Akorta.
Rosuvastatin calcium.
Hlua.
Rosistark.
Rosuvastatin SZ.
Neeg Coob.
Rosucard.
Rosulip.
Kwv Txhiaj Ntsuag.
Mertenil.
Suvardio.
Rosuvastatin Canon.
Xeb.

Cov pab pawg ntawm statins suav nrog analogues:

Leskol.
Pravastatin.
Tulip.
Rovacor.
Kwv Txhiaj Ntsuag.
Simvastol.
Cardiostatin.
Cov Ator.
Torvazin.
Rosucard.
Lovasterol.
Leskol forte.
Lipostat.
Atherostat.
Zokor forte.
Lovacor.
Simvalimite.
Akorta.
Lipobay.
Xeb.
Keebkwm.
Simvor.
Rosulip.
Apextatin.
Atorvox.
Hlua.
Torvacard.
Liprimar.
Lovastatin.
Neeg Coob.
Actalipid.
Ib Sim Neej.
Simlo.
Tevastor
Liptonorm.
Zorstat.
Simvacol.
Vasilip.
Aries
Simvastatin.
Mertenil.
Vazator.
Zokor.
Atorvastatin.
Tus tub sab.
Atoris.
Atocord.
Lipona.
Dab Dab Ntxaug.
Novostat.
Torvalip.
Holetar.
Mevacor.
Cov Atomax

Cov lus so thiab nqe

Tus nqi nruab nrab ntawm rosuvastatin (10 mg ntsiav tshuaj No. 30) hauv Moscow yog 325 rubles. Tso tawm los ntawm kev kho mob.

Lub txee lub neej ntawm cov ntsiav tshuaj yog 2 xyoos txij li hnub tsim khoom lag luam. Cov tshuaj yuav tsum muab cia rau hauv nws lub ntim thawj, hauv qhov chaw tsaus, qhuav qhov chaw ntawm qhov cua ntawm qhov siab tsis siab tshaj +25 C. Khaws tsis pub ncav cuag cov menyuam yaus.

Cov lus qhia ntxaws ntxaws txog cov tshuaj uas nrov tshaj plaws thiab tsis pheej yig rau cov tshuaj "Rosuvastatin"

Rosuvastatin yog ib qho zoo tshaj plaws thiab siv dav siv tshuaj lipid-txo qis. Yog tias, rau qee qhov laj thawj, piv txwv li, qhov tsis muaj chaw muag tshuaj hauv zos lossis cov nqi siab, tus neeg mob tsis tuaj yeem yuav cov tshuaj qub, tom qab ntawd nws tuaj yeem hloov los ntawm cov tshuaj ntxiv pheej yig, ntawm uas muaj ntau Rosuvastatin.

Cov ntaub ntawv dav dav txog cov tshuaj thiab cov lus qhia rau kev siv

Rosuvastatin (Rosuvastatin) - Qhov no yog qhov lipid-txo cov tshuaj ntawm cov IV dhau los (tshiab) los ntawm ib pawg pharmacological ntawm cov statins, cov khoom xyaw tshuaj uas yog tshuaj lom neeg ntawm tib lub npe rosuvastatin nyob rau hauv daim ntawv ntawm calcium ntsev (calcium rosuvastatin).

Cov tshuaj no yog npaj rau kev kho los ntawm cov roj (hypercholesterolemia) tsis tu ncua, uas tsis yog qhov zoo txaus rau kev kho mob nrog cov tsis siv tshuaj.Nws kuj tseem raug txiav txim siab ua ib feem ntawm txoj kev kho mob nyuaj rau lwm cov ntawv ntawm cov roj ntsha tsis txaus (dyslipidemia), rau kev tiv thaiv kev mob plawv thiab tshem tawm cov kev hloov kho atherosclerotic ntawm cov phab ntsa ntawm cov hlab ntsha.

Qhov kev txiav txim ntawm statins yog ua raws li kev txwv tsis pub muaj enzyme, uas yog lub luag haujlwm rau kev tsim cov cholesterol los ntawm lub siab (qhov chaw txog li 80% ntawm cov tshuaj).

Mechanism ntawm kev ua Rosuvastatin muaj nyob rau hauv thaiv cov enzyme - HMG-CoA reductase, uas yog "lub cev xeeb menyuam" ntawm cov tshuaj tua kabmob ua kom muaj kabmob (Chol, cholesterol) hauv lub siab. Vim tias qhov no, tus naj npawb ntawm cov neeg tau txais kev tiv thaiv kom tsawg rau cov lipoproteins uas tsis muaj ntau ntxiv, uas ua rau cov txheej txheem ua rau lawv cov hniav lwj thiab nthuav tawm ntawm lub cev.

Yog li ntawd, tawm tsam cov keeb kwm yav dhau los ntawm kev siv tshuaj, muaj qhov txo qis ntawm cov "roj" phem (LDL, LDL), thiab cov qib "cov roj" zoo (HDL, HDL) hauv cov ntshav kuj tau them rov qab.

Cov tshuaj muaj nyob rau hauv daim ntawv ntawm cov yeeb yaj kiab-cov ntsiav tshuaj, uas yuav tsum tau noj tshwj rau sab hauv (qhov ncauj), nrog tsawg kawg 100-150 ml dej, txhua lub sijhawm ntawm hnub, tsis hais noj zaub mov.

Lub qub qauv ntawm Rosuvastatin suav nrog mis qab zib (lactose) monohydrate, lub xub ntiag uas ua rau cov tshuaj tsis raug rau cov neeg mob uas tsis nkag mus rau cov feem no thiab cov neeg muaj lactase tsis txaus.

Kev kho kiag Rosuvastatin raug xaiv los ntawm tus kws kho mob nruj me ntsis ntawm tus kheej, raws qhov mob hnyav hauv txhua kis. Kev txais tos yuav pib nrog qhov tsawg kawg nkaus (5-10 mg ib hnub ib zaug) thiab nce raws li qhov tsim nyog (muab rau tsis muaj kev phiv).

Kev hais tawm lipid-txo cov nyhuv tuaj yeem pom tom qab 7-9 hnub tom qab pib kho, thiab tom qab 2-4 lub lis piam nws nce mus txog 90-100% ntawm qhov txiaj ntsig siab tshaj plaws, uas tau tswj xyuas thoob plaws tag nrho cov kev kawm ua ntu zus ntawm Rosuvastatin.

Cov tuam txhab tsim khoom twg zoo dua?

Tus thawj cov tshuaj Rosuvastatin tau tsim los ntawm Japanese tuam txhab Shionogi & Co. (Shionogi & Co), txawm li cas los xij, nws cov analogues yog tsim nyob rau hauv cov npe thoob ntiaj teb tsis muaj npe (INN) los ntawm lwm lub tuam txhab tshuaj:

Lavxias - Cov Kws Muag Tshuaj (Phstandard), Ozone (Ozon), Canonfarma (Kanonfarma), FI Obolenskoye (OBL Pharm),
tuaj txawv tebchaws - Astra Zeneca (Astra Zeneca), Gideon Richter (Gedeon Richter), Actavis (Actavis), Belupo (Belupo).

Tag nrho cov tuam txhab no tsim cov generics, i.e., luam yeeb tshuaj, cov tshuaj tiv thaiv tseem ceeb ntawm uas yog tib lub rosuvastatin, tab sis lawv txawv ntawm kev pib txhim kho los ntawm cov txheej txheem thev naus laus zis ntawm kev tsim khoom, kev lag luam lub npe thiab qhov sib piv ntawm cov neeg zam.

Txij li cov piv txwv ncaj ncaj yuav luag sib luag nrog cov thawj, txij li qhov pom ntawm nws cov hauj lwm zoo, nws tsis tseem ceeb dab tsi uas lub tuam txhab muab kev nyiam rau thaum yuav khoom, tab sis muab hais tias Rosuvastatin noj rau lub sijhawm ntev, nws ua rau muaj kev txiav txim siab saib xyuas cov tshuaj muaj nqi pheej yig dua.

Cov analogues nto moo tshaj plaws thiab hloov chaw rau rosuvastatin

Ua ntej txiav txim siab qee yam tshwj xeeb thiab hloov pauv rau Rosuvastatin, nws tsim nyog sau cia tias, txawm tias tau teem caij mus ntsib tus kws kho mob, tus neeg mob muaj cai xaiv qhov tsis tas li, tsom mus rau nws tus kheej nyiam, lub hnab nyiaj thiab tus neeg tsis txaus siab rau cov khoom xyaw ntxiv hauv cov lus muaj. Qhov loj tshaj plaws yog kev ua raws li cov koob tshuaj muaj qhia thiab kev coj ua tshuaj.

Roxera muaj cov tshuaj muaj zog tshwj xeeb tshaj plaws uas tso cai rau rosuvastatin tso tawm tshwj xeeb rau hauv txoj hnyuv me, qhov twg cov ntsiav tshuaj tau nqus dej tsis hloov, thiab tsis raug cuam tshuam los cuam tshuam ntawm lub plab ua kua.

Cov yam ntxwv ntawm muaj pes tsawg leeg: butyl methacrylate thiab methyl methacrylate copolymer ntxiv rau lub plhaub.

Tuam txhab tsim khoom lag luam: KRKA, Slovenia.

Tus nqi tshuaj: los ntawm 383 RUB / 30 pcs 5 mg txog 1617 rubles / 90 pcs. 20 mg txhua.

Rosucard (Rozucard) yog tus cwj pwm los ntawm kev siv lub cev zoo (ntau dua 20%), tab sis cov tshuaj rosuvastatin tau sai sai tawm ntawm lub cev, thiab yog li ntawd cov tshuaj muaj cov cim zoo tshaj plaws rau kev kho mob.

Cov yam ntxwv ntawm muaj pes tsawg leeg: es tsis txhob hypromellose los ntawm thawj qhov qauv, croscarmellose yog siv los ua hmoov ci.

Tuam txhab tsim khoom lag luam: Zentiva, Czech koom pheej.

Tus nqi tshuaj: los ntawm 613 rub. / 30 pcs. 10 mg rau 2708 rubles / 90 pcs. 40 mg txhua.

Cov kws kho mob pom zoo

Txo cov roj (cholesterol) kom tsawg thiab tiv thaiv atherosclerosis yam tsis muaj kev phiv, cov kws txawj pom zoo choledol. Tshuaj niaj hnub:

raws amaranth siv hauv kev kho mob plawv,
tsub kom cov cholesterol ntau "zoo", txo cov khoom "siab" los ntawm lub siab,
txo txoj kev pheej hmoo ntawm lub plawv nres thiab mob hlab ntsha tawg,
pib ua yeeb yam tom qab 10 feeb, qhov tshwm sim tseem ceeb yog pom tshwm tom qab 3-4 lub lis piam.

Kev ua tau zoo yog paub tseeb los ntawm kev kho mob thiab kev tshawb fawb ntawm Lub Tshawb Fawb Lub Chaw Kho Mob.

Mertenil (Mertenil) muaj qhov siab ntawm kev ua kom huv ntawm cov khoom ua kom nquag plias. Qhov no ua kom zoo tiv thaiv cov tshuaj muaj tsawg dua kev phiv, uas yog qhov tshwj xeeb tshaj yog thaum noj rosuvastatin hauv cov neeg laus.

Cov yam ntxwv ntawm muaj pes tsawg leeg: sib haum nrog qhov qub, tshwj tsis yog rau cov tshuaj uas siv los pleev xim lub plhaub.

Tuam txhab tsim khoom lag luam: Gedeon Richter, Hungary.

Cov nqi hauv cov chaw muag tshuaj: los ntawm 478 rub. / 30 pcs. 5 mg txog 1439 rubles / 30 pcs. 40 mg txhua.

Rosulip (Rosulip) yog cov tshuaj pheej yig dua ntawm Rosuvastatin, uas muaj lub siab ua kom zoo dua thiab maj mam ua kom zoo, uas tso cai rau koj los ua kom maj mam tsim cov tshuaj kho qhov xav tau ntawm cov tshuaj nquag hauv lub cev.

Cov yam ntxwv ntawm muaj pes tsawg leeg: muaj cov rosuvastatin tsis yog nyob rau hauv daim ntawv ntawm calcium, tab sis nyob rau hauv daim ntawv ntawm zinc ntsev (rosuvastatin zinc).

Tuam txhab tsim khoom lag luam: EGIS (EGIS Pharmaceuticals PLC), Hungary.

Tus nqi tshuaj: los ntawm 469 RUB / 28 pcs 5 mg txog 1087 rubles / 28 pcs. 20 mg txhua.

Crestor (Crestor) - tsuas yog thawj cov tshuaj raws rosuvastatin. Cov tshuaj yeeb yaj kiab no tau tsim los ntawm cov txheej txheem ua haujlwm zoo ntawm cov tshuaj yeeb dej caw thiab, yog tias koj tso siab rau cov neeg mob cov lus pom zoo, kev nkag siab zoo dua, tab sis ntawm tus nqi nws tseem kim tshaj li lwm cov generics.

Cov yam ntxwv ntawm muaj pes tsawg leeg: Tag nrho cov khoom xyaw yog zoo tib yam rau hauv daim ntawv qhia thawj.

Tuam txhab tsim khoom lag luam: Astra Zeneca, United Kingdom.

Cov nqi hauv cov chaw muag tshuaj: los ntawm 1756 rub. / 28 pcs. 5 mg txhua rau 5036 rub./28 pcs. 40 mg txhua.

Tevastor yog ib qho zoo tshaj plaws analogues ntawm Rosuvastatin, vim nws sai sai hauv lub cev, ua rau lub suab tawm suab kho, thiab tib lub sijhawm raug nqi ntau pheej yig dua li cov tshuaj qub.

Cov yam ntxwv ntawm muaj pes tsawg leeg: yuav luag cov lenten zoo ib yam li daim tseem (tshwj tsis yog zas xim).

Tuam txhab tsim khoom lag luam: TEVA (TEVA Pharmaceutical Industries Ltd), Ixayees.

Tus nqi tshuaj: los ntawm 341 rub. / 30 pcs. 5 mg txog 1522 rubles / 90 pcs. 20 mg txhua.

Rosuvastatin-SZ

Rosuvastatin-SZ (Rosuvastatin-SZ) - niaj hnub no nws yog qhov hloov pheej yig tshaj rau Rosuvastatin los ntawm cov chaw tsim khoom hauv Lavxias. Txawm hais tias tus nqi tsawg heev, nws tsis qis dua nyob rau hauv zoo rau lwm yam generics thiab tseem muaj cov khoom zoo ib yam rau thawj.

Cov yam ntxwv ntawm muaj pes tsawg leeg: hlau oxide siv los ua zas yog hloov los ntawm cov kua roj vanish ntawm peb ntau hom.

Tuam txhab tsim khoom lag luam: FC Severnaya Zvezda ZAO, Russia

Tus nqi tshuaj: los ntawm 178 rub. / 30pcs. 5 mg txog 684 rubles / 30 pcs. 40 mg txhua.

Ntxiv nrog rau statins, muaj lwm yam txhais tau tias. Cov nyeem nyeem ntawv pom zoo tshuaj ntuj, uas, ua ke nrog kev noj haus thiab kev ua si, txo qis cov roj (cholesterol) tom qab 3-4 lub lim tiam. Cov tswv yim ntawm cov kws kho mob >>

Rosart (Rosart) muaj txhua qhov zoo ntawm cov tshuaj qub thiab tsis tshua muaj cov txiaj ntsig tsis zoo rau lub cev, vim tias ob qho tib si cov tshuaj nquag thiab cov khoom siv pabcuam tau muab ntxuav kom huv. Peb tuaj yeem hais tias qhov no yog qhov hloov tau ntau tshaj plaws rau rosuvastatin.

Cov yam ntxwv ntawm muaj pes tsawg leeg: tag nrho cov khoom xyaw yog tib yam li hauv kev npaj thawj zaug.

Tuam txhab tsim khoom lag luam: Actavis Pawg, Iceland

Cov nqi hauv cov chaw muag tshuaj: los ntawm 426 RUB / 30 pcs 5 mg rau 2347 rub./90 pcs. 40 mg txhua.
Cov khoom uas txo cov roj cholesterol thiab ntxuav cov hlab ntshav.

Txhua hom tshuaj zoo tshaj plaws rau cov roj (cholesterol) zoo hauv daim ntawv ntawm cov ntsiav tshuaj.

Yuav siv cov tshuaj Rosuvastatin Canon li cas?

Rosuvastatin Canon, tsim los ntawm Canonfarm Ntau Lawm CJSC, yog ib txoj hauv kev txo qis triglycerides thiab roj (cholesterol).

Yuav noj li cas

Ua ntej siv, cov ntsiav tshuaj yog contraindicated rau zom, nws yog noj tag nrho, ntxuav cia nrog dej tseem huv. Qhov ntau npaum yog xaiv los ntawm tus kws kho mob mus kawm, coj mus rau hauv tus account qhov ua tau zoo ntawm lwm txoj hauv kev kho mob, teb rau kev kho, lipid concentration, qhov kev pheej hmoo ntawm kev txhim kho pathologies ntawm cov hlab plawv system.

Qhov pom zoo kom pib noj yog 10 mg ib hnub ib zaug. Kev nce ntxiv ntawm cov tshuaj yog tias tau pom zoo tom qab 4 lub lis piam ntawm kev noj tshuaj. Tom qab nce qhov koob tshuaj, ib qho kev kuaj mob yog qhov tsim nyog los ntsuas qib ntawm lipids.

Phiv fab ntawm rosuvastatin canon

Noj tshuaj yuav ua rau kiv taub hau, xeev siab, quav tawv lossis zawv plab, mob asthenic. Muaj qee zaus, tus neeg mob tsim kho nco qab, ua kom muaj kab mob siab, ua tsis taus pa, mob taub hau.

Cov tshuaj tiv thaiv ntawm qhov system musculoskeletal rau cov tshuaj nquag yuav yog kev txhim kho ntawm myopathy, arthralgia, myalgia, rhabdomyolysis nrog mob raum tsis ua haujlwm. Lwm cov kev mob tshwm sim ntawm cov tshuaj muaj xws li:

Mob ntshav qab zib Hom 2.
Kev Proteinuria
Kev Nyuaj Siab
Pw tsis tsaug zog, pw tsis tsaug zog.
Txo tsawg libido.

Nrog rau kev txhim kho ntawm qhov lus teb tsis zoo los ntawm kev tiv thaiv kab mob, ua pob ntawm daim tawv nqaij, urticaria, thiab Quincke edema yuav tshwm sim.

Cov nyhuv ntawm cov tshuaj provokes kev hloov pauv hauv qhov ntsuas, nrog rau cov kev ua ntawm hepatic transaminases, nce ntxiv nyob rau hauv cov piam thaj, cov thyroid hormones thiab bilirubin.

Siv thaum cev xeeb tub thiab lactation

Cov txiaj ntsig xav tau los ntawm kev noj tshuaj ntau dua qhov kev ua tsis zoo rau tus me nyuam hauv plab, yog li cov tshuaj no tsis ua haujlwm thaum xeeb tub. Tsis muaj cov ntaub ntawv hais txog kev nyab xeeb ntawm cov tshuaj thaum lactation, uas yuav tsum tsis kam kho lossis hloov tus menyuam mus rau kev pub mis noj thaum kho.

Kev Ntsuam Xyuas Rau Neeg Mob

Roman, hnub nyoog 43 xyoo, Moscow

Cov tshuaj tau tawm los txo qis kev pheej hmoo ntawm lub plawv nres. Rau lub hlis, qhov ntsuas cov roj (cholesterol) tau hloov pauv kom zoo dua. Kuv haus cov ntsiav tshuaj raws li tag nrho cov lus qhia ntawm tus kws kho plawv.

Cov lus qhia rau kev siv sau cov npe ntev ntawm cov kev mob tshwm sim, muaj ntau qhov tsis zoo tshuaj xyuas hauv Is Taws Nem, yog li thaum xub thawj Kuv ntshai haus cov tshuaj no.

Tab sis tsis muaj qhov tsis xav tau tshwm sim, thiab qhov tshwm sim tau siab.

Olena Alekovna, 51 xyoo, Kiev

Kev kho mob tau pib nrog Dibikor, tom qab mob ntxiv, thaum qhov nce ntawm triglycerides tseem ceeb, Kuv yuav tsum pib haus cov tshuaj no. Qhov tshwm sim xav tau, tab sis nws qhov ua tiav tau kim. Tshaj tawm cov kev mob tshwm sim. Tom qab raug yuam, Dibicor tau raug tsa.

Cov tshuaj zoo heev, tab sis nws muaj qhov tsis zoo ntawm lub plab zom mov, ua rau pom qhov tshwm sim ntawm npau suav phem, mob taub hau. Kuv yuav tsum tau kho thiab thev dhau qhov tsis zoo tshwm sim, thiab tsuas yog tom qab ntawd nrhiav txoj hauv kev kom tshem tau lawv.

Dosage daim ntawv thiab muaj pes tsawg leeg ntawm statin

Hauv cov khw muag tshuaj network, Rosuvastatin muag hauv daim ntawv ntawm cov ntsiav tshuaj convex puag ncig hauv lub plhaub zaj duab xis paj yeeb, npaj rau qhov ncauj tswj hwm (sab hauv).

Lub hauv paus tseem ceeb ntawm cov tshuaj yog rosuvastatin, qhov kev tso tawm ntawm rosuvastatin hauv cov ntsiav tshuaj nyob ntawm daim ntawv tso tawm: 5.10 lossis 20 mg hauv 1 daim.Statin ntxiv nrog cov khoom siv pabcuam: hypromellose, hmoov txhuv nplej siab, titanium dioxide, crospovidone, microcrystalline cellulose, silicon dioxide, zas carmine, triacetin, silicon dioxide, magnesium stearate.

Cov tshuaj tau ntim rau hauv ib lub thoob blister nrog 10 lub hlwb. Hauv qhov chaw thawv duab ntawv tuaj yeem muaj 3 lossis 6 ntawm cov paib, ntxiv los ntawm cov lus qhia rau kev siv tshuaj.

Cov yam ntxwv ntawm Pharmacological

Cov nquag ua haujlwm ntawm cov tshuaj muaj lipid-txo cov nyhuv. Rosuvastatin inhibits qhov enzyme HMG-CoA reductase, lub luag hauj lwm rau kev tsim cov mevalonate - cov ua ntej ntawm cov cholesterol. Cov cuab yeej muaj qhov cuam tshuam ncaj qha rau hepatocytes (mob hlwb), lub luag haujlwm rau kev tsim cov roj (lawv cov roj) rau lawv.
Los ntawm nce tus naj npawb tsawg kawg lipoprotein receptors nyob rau saum npoo ntawm hepatocides, nws ua kom tshem tawm cov roj cholesterol ntau dhau los ntawm cov roj ntsha, pab txo VLDL ntau lawm, vim nws yog lipoproteins nrog qhov tsawg kawg nkaus uas ua rau feem ntau mob siab rau ntawm cov hlab ntshav.

Ib qho tseem ceeb sib txawv ntawm Rosuvastatin thiab lwm yam statins yog tias nws tsis tsuas yog sib ntaus nrog "tsis zoo" cov roj (cholesterol), tab sis kuj tseem nres qeeb qeeb mob, uas, raws li ntau tus kws tshawb fawb, yog qhov tseem ceeb ntawm atherosclerosis.

Cov tshuaj ua rau cov tshuaj tiv thaiv ntawm cov tshuaj tiv thaiv nitrogen, uas ua rau kom muaj kev so ntawm cov hlab ntshav, thiab tsim kom muaj lub npe hu ua pleiotropic (ntxiv) cov nyhuv.

Tom qab siv statin, cov khoom xyaw nquag tuaj sai sai, txawm hais tias tsis ua kiag li nkag mus rau hauv qhov system, yog tusyees faib dua cov nqaij ntawm lub cev. Nws yog nqus tau qeeb tshaj qhov nws tau ua ke thiab lub sijhawm tshem tawm tau ntev tshaj.

Qhov siab tshaj plaws ntshav plasma ntawm cov khoom xyaw nquag yog pom 5 teev tom qab noj. Txawm hais tias qhov tseeb tias cov tshuaj tau sau tseg hauv kev noj tshuaj tsawg dua li cov qauv sib piv, cov chaw muag tshuaj tso cai rosuvastatin muaj kev cuam tshuam tsawg dua nrog lwm cov tshuaj piv rau statins ntawm lwm tiam. Hmoov tsis zoo, qhov no tsis cawm nws ntawm kev phiv.

Tsis zoo li feem ntau cov tshuaj statins, cov tshuaj yuav luag tsis txaus nyob rau hauv daim siab: 5% ua rau lub raum, thiab feem ntau yog (90%) nws tawm txoj hnyuv hauv nws daim ntawv qub.

Cov Kev Txwv thiab contraindications

Txog cov ntsiav tshuaj rosuvastatin, cov lus qhia rau kev siv pom zoo rau cov npe uas muaj ntau yam kev tiv thaiv thiab kev txwv:

Intolerance rau cov khoom xyaw ntawm cov mis,
Lub sijhawm ntawm cev xeeb tub thiab lactation, tsis muaj kev tswj kom tsis muaj txaus thaum muaj hnub nyoog xeeb tub, uas tsis pub cais tawm qhov kev xav tsis pom thaum lub sijhawm kho nrog Rosuvatin,
Cov menyuam yaus lub hnub nyoog (txog 18 xyoo), tshwj tsis yog cov neeg hluas nrog kev tiv thaiv kab mob hypercholesterolemia,
Mob siab ua haujlwm tsis zoo vim kev ua txhaum ntawm nws lub luag haujlwm thaum muaj kev puas tsuaj rau hepatocytes nrog lub siab ntshav cov ntsiab lus ntawm hepatic transaminases (enzymes),
Siv lub sijhawm ntawm cyclosporine,
Myopathy (ib qho mob ntawm cov leeg nqaij mob leeg uas mob pob txha) lossis ib tug nyiam txhim nws.

Kev siv cov tshuaj nyob rau hauv qhov siab tshaj (40 g) ntau npaum li cas muaj ntxiv contraindications:

Kev haus cawv mus ntev
Cov xwm txheej ua rau muaj qhov nce ntxiv ntawm ntshav plasma concentration ntawm rosuvastatin,
Xav tias yog myopathy,
Lub raum tsis ua hauj lwm
Myotoxicity hauv kev kho mob ntawm lwm yam tshuaj uas txwv cov enzyme HMG-CoA reductase,
Kev kho zoo nrog fibrates.

Qhov ntau kawg rau cov tshuaj tsis yog kws kho rau cov neeg ntawm haiv neeg Mongoloid. Cov xwm txheej no yuav tsum tau ua lub hauv paus rau kev saib xyuas ceev faj ntawm statin hauv kev siv tshuaj ntau. Ua ntej sau ntawv ntawm Rosuvastatin, tus kws kho mob yuav tsum paub tseeb tias nws yuav tsum tau siv, yog li nws yog qhov tseem ceeb uas yuav tau qhia nws txog txhua yam tshuaj, kev noj zaub mov, tshuaj ntsuab uas tam sim no tau noj.

Rosuvastatin: cov lus qhia rau kev siv

Cov ntsiav tshuaj yuav tsum tau haus dej nrog txhua lub sijhawm. Noj mov tsis muaj kev cuam tshuam nws cov kev ua ub no, tab sis txij li cov roj (cholesterol) nyob rau thaum hmo ntuj, cov tshuaj feem ntau tau noj rau yav tsaus ntuj, siv ib zaug.

Yog tias cov tshuaj statins siv rau thawj zaug, tsis pub ntau tshaj 5-10 mg / hnub yog kws kho. hauv ib mus. Ntawm qis efficiency kev kho mob koob tshuaj yog ob npaug rau 20 mg / hnub. Qhov siab tshaj plaws qhov niaj hnub niaj zaus (40 g) yog kho tsuas yog rau mob hnyav hypercholesterolemia, txij li kev muaj peev xwm ntawm kev phiv ntau dua.

Nrog concomitant lub raum lossis hepatic ua haujlwm tsis txaus, ib qho kev nyiam ntawm myopathy, cov neeg sawv cev ntawm hom Mongoloid, qhov kev pom zoo thawj zaug tsis pub tshaj 5 g. Lub sijhawm siv ntawm kev sim mus los ntawm tus kws kho mob tau txiav txim siab, tab sis kev kho kom haum yog qhov ua tau tsis pub dhau ib hlis tom qab.

Thawj qhov cuam tshuam pom tau tshwm sim tom qab ib lim piam, tom qab ob qho tshuaj nws twb cuam tshuam 90%. Nyob rau hauv tag nrho cov zog, Rosuvastatin nthuav qhia nws tus kheej hauv lub lim tiam thib peb ntawm kev ua kom tsawg. Yav tom ntej, cov txiaj ntsig tiav tau txais kev cawm.

Cov tshuaj tsis tau noj hauv kev kawm, statins yog tshuaj rau lub neej, nrog kev hloov kho ntau ntau yog tias tsim nyog. Yog tsis muaj zaub mov noj thiab ua kom lub cev muaj zog, kev kho tshuaj tsis muaj txiaj ntsig. Yuav ua li cas txo cov roj (cholesterol) nyob hauv cov hauv kev pheej yig, saib cov yeeb yaj kiab

Sab sij huam

Tawm tsam keeb kwm yav dhau los ntawm kev kho mob statin, kev txhim kho ntawm qhov tsis tuaj yeem tsis pom kev cuam tshuam los ntawm ntau lub plab hnyuv siab raum yog ua tau:

Lub plab zom mov - nquag dyspeptic cuam tshuam, hloov lub suab ntawm txoj hnyuv tsiv, qee zaum tus kab mob nqus dej ua kom yoog,
CNS - kev ua kom tsis muaj zog, mob taub hau, ua kom sib haum,
Endocrine system - hom 2 mob ntshav qab zib mellitus (DM),
Cov kabmob plab hnyuv siab raum - proteinuria thiab hematuria,
Musculoskeletal system - myasitis, myalgia, rhabdomyolysis (cov leeg puas tsuaj nrog kev tsim cov sib txuas rau lub raum txaus ntshai), tshwj xeeb tshaj yog txaus ntshai nrog nyiam nyiam myopathy,
Ua xua - ua xua, tawm pob, thiab khaus ntawm daim tawv.

Qhov ntxim nyiam ntawm qhov tsis pom txog qhov yuav tshwm sim yog koob tshuaj. Thaum kho nrog rosuvastatin nrog qhov siab tshaj plaws (40 mg / hnub), lawv cov ntau zaus nce. Cov tsos mob ntawm kev tawm tsam yog lub hauv paus rau kev hloov kho koob tshuaj lossis hloov chaw muag tshuaj.

Cov lus pom zoo tshwj xeeb

Thaum xaiv rosuvastatin, tus kws kho mob coj mus rau hauv tus account cov lus qhia tshwj xeeb:

Kev kho mus sij hawm ntev nrog statin, tshwj xeeb tshaj yog thaum txhaj tshuaj ntau, qhia txog kev soj ntsuam ntshav ntawm cov ntshav ntawm CPK enzyme (creatine phosphokinase) kom tiv thaiv cov kab mob ntawm cov leeg, tshwj xeeb tshaj yog muaj caj ces ntawm myopathy.
Cov tib neeg siv cov tshuaj uas ua rau cov leeg ntshav qab zib HMG-CoA reductase yuav tsum siv kev soj ntsuam kom zoo thiab kev tshuaj xyuas tus neeg mob cov mob.
Ua ntej noj cov tshuaj statins, tus neeg mob yuav tsum qhia txog cov kev tsis zoo uas yuav tshwm sim ntawm cov leeg, yog li tej leeg mob yuav tsum yog ib qho laj thawj rau mus ntsib kws kho mob.
Tawm tsam keeb kwm yav dhau los ntawm kev siv Rozuvatsatin, qee tus neeg mob myasthenia (leeg tsis muaj zog), ua rau muaj kev cuam tshuam ntawm kev ua kom muaj zog ntawm cov kabmob ntawm autoantibodies, tau sau tseg.
Nrog kev hloov kho koob tshuaj, raws li txhua 2-4 lub lis piam, cov ntsiab lus plasma cov roj thiab lipids yog saib xyuas.
Ua ntej pib qhov pib thiab ntxiv dua, tom qab ob peb lub lis piam, ib qho kev kuaj xyuas ntawm qhov ntsuas tau zoo ntawm lub siab yog qhov tsim nyog.
Rosuvastatin muaj lub peev xwm los cuam tshuam nrog lwm cov tshuaj, thaum noj lawv, koj yuav tsum ceeb toom tus kws kho mob ua ntej teeb tsa kev kho mob.
Txij li cov kev npaj muaj lactose, rau qhov ua txhaum cai ntawm kev nqus ntawm cov carbohydrates hauv cov hnyuv (lactase deficiency, glucose-galactose malabsorption), cov yeeb yam no yuav tsum raug coj los siv.
Statin cuam tshuam tsis zoo rau kev nqus ntawm cov piam thaj, ib qho kev nce ntxiv hauv nws lub plasma concentration ua rau pom qhov tshwm sim ntawm cov ntshav qab zib hom 2, kev saib xyuas lub cev ntawm nws cov ntsuas yog qhov yuav tsum tau ua.
Tsis muaj ntaub ntawv hais txog cov nyhuv ntawm rosuvastatin ntawm kev mloog zoo, lub hlwb kev ua haujlwm, thiab tus cwj pwm ntawm cov tshuaj tiv thaiv.

Hauv cov khw muag tshuaj, cov tshuaj tso tawm nyob rau hauv qhov muaj mob ntawm kws kho mob, kev kho tus kheej nrog statins yog qhov tsis tuaj yeem lees paub.

Cov txiaj ntsig ntawm kev sib txuam nrog lwm cov tshuaj

Thaum noj tib txhij nrog lwm yam tshuaj, nws muaj peev xwm hloov pauv lub zog ntawm statin lossis cov tshuaj no, yog li tus kws kho mob yuav tsum paub thiab coj mus rau hauv txhua tus nuances.

Sib cuag nrog nicotinic acid derivatives ua tau kom muaj kev cuam tshuam ntawm lub raum thiab rhabdomyolysis.
Kev sib cuam tshuam nrog cov diuretics ua rau muaj kev pheej hmoo ntawm kev txo qis ntawm cov tshuaj steroid.
Txo kev siv statin nrog lwm cov tshuaj lipid-txo qis kev pheej hmoo ntawm phiv ntau yam.
Sib koom nrog plauv nres glycosides yuav ua rau kom muaj cov ntsiab lus digoxin.
Immunosuppressants ua ke nrog rosuvastatin tuaj yeem cuam tshuam kev loj hlob ntawm lub raum pathologies thiab rhabdomyolysis.
Tiv tauj nrog cov tshuaj anticoagulants tsub kom ntshav khov ntau dua.
Cov tshuaj antifungal hauv kev sib cuam tshuam ua rau muaj kev pheej hmoo ntawm lub raum khiav lag luam thiab rhabdomyolysis.
Kev haus dej haus cawv ua ke yuav muaj feem ntau ua mob rau daim siab.

Pab nrog overdose

Nrog rau kev siv tib lub sij hawm ntau tshaj ntawm cov ntsiav tshuaj ntau dhau ntawm cov tshuaj txhua hnub, cov cim ntawm kev siv ntau dhau tsis tshwm sim, vim tias pharmacokinetics ntawm cov tshuaj ua kom nquag plias ntawm cov tshuaj tseem nyob rau theem pib.

Kev haus ntau dhau lawm tuaj yeem ua rau muaj kev cuam tshuam ntawm kev phiv uas ua rau lub plab txoj hnyuv plab txhawm rau, kev siv txoj hnyuv, thiab kev kho tus mob.

Qhov tshuaj tiv thaiv tshwj xeeb rau rosuvastatin tsis tau tsim tawm.

Cov tshuaj zoo sib xws

Rosuvastatin tau paub hauv lub khw muag tshuaj txij li xyoo 2003. Raws li kev kho mob nyhuv thiab muaj pes tsawg leeg rau

Rosuvastatin analogues hnub no yog:

Rosuvastin SZ,
Mertenil
Tevastor
Kwv Txhiaj Ntsuag
Rosuvastatin Canon,
Rosicore
Rosulip,
Neeg Coob
Rosistark,
Rosart,
Akorta,
Rosucard,
Torvacard.

Raws li tus nqi kho mob, pawg no tuaj yeem muab faib ua 3 pawg: cov peev nyiaj ntau tshaj: Rosuvastatin Canon, Rosuvastatin SZ, Akorta (250-650 rubles), tus nqi nruab nrab: Rosart, Mertenil, Tevastor, Roxer, Rosucard, Rosulip (400-900 rubles) , nyob zoo: Crestor (1100-2200 rub.). Rau rosuvatin analogues, tus nqi tsom xam tau nqa tawm rau lub thawv nrog 10 mg ntsiav tshuaj.

Cov neeg siv kev ntsuas

Txog Rosuastatin, cov kev txheeb xyuas yog tag nrho ntawm kev ntshai txog qhov kev txhim kho uas yuav muaj kev phiv, tab sis lawv tuaj yeem nyuaj hu ua hom phiaj. Cov kev tsis txaus siab feem ntau (ua xua, qaug zog, mob leeg) yog los ntawm thawj Rosuvastatin, tab sis los ntawm cov pheej yig dua ua nyob rau hauv Is Nrias teb thiab cov teb chaws ntawm lub qub Soviet. Cov kws kho mob muab Krestor lossis cov txiaj ntsig zoo ua tau zoo tsim hauv Tebchaws Europe Sab Hnub Tuaj.

Cov txiaj ntsig ntawm thoob ntiaj teb kev kawm ntau ntawm ROSU-PAZ ntawm Rosuvastatin tuaj yeem pom ntawm cov yeeb yaj kiab

Rosuvastatin yog cov tshuaj kho kom tswj hwm atherosclerosis. Nrog rau kev ua kom cov lipid sib npaug, qhov zoo li ntawm lub plawv nres, mob stroke qis, tsis tas yuav tsum ua stenting thiab mob hlab plawv phais, thiab txhim kho cov ntshav ncig mus rau cov ceg los ntawm kev phais mob.

Kev sib tw tseem ceeb niaj hnub no yog nyob nruab nrab ntawm cov tshiab tshaj plaws ntawm statins. Rosuvastatin muaj cov roj ntsha zoo dua hauv cov roj (cholesterol), tab sis coj mus rau hauv nws cov kev mob tshwm sim, qee zaum xav pom zoo kom sau ntawv rau lwm cov neeg sawv cev.

Noj txawm tias cov tshuaj noj muaj zog no tsuas tuaj yeem ua tiav qhov kev hloov mus rau cov xwm txheej tshiab ntawm lub neej, nws yuav tsis hloov qhov kev xav tau ntawm kev noj haus thiab cov leeg lub cev.

Cov kws kho mob tshuaj xyuas

Elena Alekseevna, kws kho plawv, Moscow

Cov tshuaj yog cov siv dav dav ntawm cov tshuaj British, tab sis nws muaj txiaj ntsig zoo. Yog tias koj ua raws li kev noj zaub mov noj thiab xaiv cov tshuaj noj kom tsim nyog, cov kev mob tshwm sim tsis tshua muaj tshwm sim thiab mob sib khuav xwb.Tib lub sijhawm, tus nqi ntawm cov tshuaj tseem pheej yig rau feem ntau cov neeg mob.

Tatyana V., phlebologist, Samara

Feem ntau, varicose leeg tsis yog tsuas yog tshwm sim ntawm malfunctions ntawm cov hlab plawv system. Txhawm rau kom ua tau zoo ntawm kev kho, nws yuav tsim nyog los txo qis ntawm cov roj (cholesterol), uas ua kom muaj kev siv cov statins, tab sis nws yuav tsum yaum tus neeg mob kom ua raws txhua qhov kev qhia txog kev noj haus, lub sijhawm noj tshuaj thiab noj ntau npaum li cas.

Cov kab ke hauv chav kawm kho mob ntawm cov ntsiav tshuaj yog qhov tsim nyog muaj mob hnyav thiab tsuas yog tom qab sab laj nrog kws kho plawv ua ntej, kev teem caij noj haus kom tsim nyog. Cov tshuaj muab tau zoo thiab ua kom tiav.

9 muaj txiaj ntsig zoo thiab tsis muaj txiaj ntsig zoo ntawm Rosuvastatin

Ntsiav tshuaj Cheebtsam
Analogues ntawm cov tshuaj

Rosuvastatin thiab nws cov tshuaj noj tau txhawm rau muab cov roj (cholesterol) hauv cov ntshav siab tshaj qhov qub. Cov tshuaj yog zwm rau cov chav kawm ntawm statins ntawm lub xeem (4 tiam). Piv nrog rau lwm cov tshuaj nyob rau hauv pab pawg no, rosuvastatin yog ib txoj kev ua tau zoo dua thiab muaj kev nyab xeeb.

Nws tau tsim synthetically thiab qhia txog cov khoom hauv hydrophilic, qhov txiaj ntsig ntawm qhov nws tsis muaj suab nrov hais txog lub siab.

Cov tshuaj ua tau zoo tsim kev tiv thaiv cov tshuaj lipoproteins uas tsis muaj ntau, uas ua cov tshuaj tseem ceeb uas cov roj (cholesterol) yog tsim los.

Ntxiv rau, kev noj cov tshuaj no tsis ua rau mob nqaij pob txha thiab lwm yam kab mob pathologies los ntawm sab ntawm cov leeg nqaij. Qhov tsim nyog cov nyhuv yog manifested twb ib lub lim tiam tom qab pib ntawm kev siv, thiab los ntawm 4 lub lis piam nws ua lub siab tshaj plaws thiab nrog kev kho mob tsis tu ncua kav ntev heev. Cov kev zoo no ua rau rosuvastatin ua ib lub siab xav tau cov tshuaj rau cov neeg mob uas xav tau qis roj.

Ntsiav tshuaj Cheebtsam

Cov tshuaj phiv tshuaj ntawm cov tshuaj yog calcium ntsev ntawm rosuvastatin. Ntxiv rau, cov muaj pes tsawg leeg suav nrog ntau qhov ntawm cov khoom siv ntxiv, uas lawv tau ua lub luag haujlwm:

Microcrystalline cellulose yog adsorbent zoo, uas yog excreted tsis hloov pauv ntawm tib neeg lub cev. Hauv tshuaj muaj pes tsawg leeg, nws ua haujlwm uas muab tub lim thiab cov tshuaj uas ua hauj lwm rau txhua qhov sib xyaw.
Lactose Monohydrate. Siv los txhim kho qhov saj ntawm cov tshuaj. Txawm li cas los xij, cov tshuaj no ua rau nws tsis tuaj yeem noj cov ntsiav tshuaj rau cov tib neeg kev txom nyem los ntawm kev tsis txaus siab lossis lactase tsis txaus.
Tshuaj Calcium Phosphate Qhov no yog cov khoom sib txuam, uas suav nrog cov xim hlau thiab calcium phosphoric acid. Cov tshuaj tiv thaiv hauv cov ntsiav tshuaj pab kom cov kab mob sib xyaw ua ke.
Magnesium stearate. Facilitates txheej txheem ntsiav tshuaj thiab ua haujlwm uas muab tub lim muaj kev nyab xeeb rau lub cev.
Hydroxypropyl methylcellulose yog cov tshuaj pleev ib ce tshwj xeeb uas yog qhov tseem ceeb rau kev tsim cov txheej txheem ntawm daim ntawv ntau npaum.
Povidone ua ib yam dab tsi uas ua kom cov tshuaj lom tsis zoo rau lub cev, nrog rau cov uas tau tsim los ntawm kev ua ntawm rosuvastatin.
Triacetin yog kev pom zoo ntxiv khoom noj (E1518). Raws li ib feem ntawm cov ntsiav tshuaj, nws ua raws li cov yas yas thiab cov tshuaj noo noo, uas yog qhov tseem ceeb rau cov txheej txheem.
Dyes - hlau oxide thiab titanium dioxide muaj kev nyab xeeb ntxiv txhawm rau txhim kho cov tsos ntawm cov tshuaj.

Rosuvatatin ntsiav tshuaj siv rau cov roj (cholesterol) siab dua tus txheej txheem yog tsim los ntawm ntau lub tuam txhab kws kho mob nyob hauv ntau lub npe. Tag nrho ntawm lawv yog cov ncaj qha analogues, uas yog, lawv muaj tib yam khoom muaj nqis.

Tus thawj cov tshuaj Krestor yog tsim los ntawm lub tuam txhab Askiv thiab muaj lub koob npe nrov ua cov tshuaj zoo tshaj plaws. Txhua lwm yam tshuaj nyob qhov twg cov tshuaj ua kom nquag plias yog rosuvastatin yog cov tshuaj ntxuav tawm.

Lawv txawv ntawm cov thawj hauv cov nqi thiab yuav muaj qhov sib txawv me ntsis ntawm cov koomhaum pabcuam, uas tsis cuam tshuam rau lawv cov haujlwm. Qhov point no yuav tsum tau coj mus rau hauv tus account nrog nce rhiab heev rau qee yam tshuaj.