Formin analogues
Tshuaj Ntshav Cov Tshuaj (Ntsiav Tshuaj) Ntsuam Xyuas: 37
Chaw tsim tshuaj paus: Cov Tshuaj Zoo Li Qub-Leksredstva (Russia)
Cov Ntawv Tso Tawm:
- Tab. 50 mg, 30 pcs., Nqe txij li 57 rubles
- Tab. 50 mg, 60 pcs., Nqe ntawm 99 rubles
Cov lus qhia rau kev siv
Formmetin yog qhov hloov pheej yig rau Glucofage, tsim los txo cov ntshav qabzib. Muaj nyob rau hauv cov ntsiav tshuaj muaj 0.5, 0.85 lossis 1 g ntawm metformin. Nws tuaj yeem ua rau lub cev ua rau lub plab tsis zoo, ua pob rau ntawm daim tawv nqaij, thiab yog tias muaj kev noj ntau dhau - lub qog ntshav thiab cov kab mob lactic acidosis tuaj yeem ua rau tuag taus.
Analogs ntawm cov tshuaj Formetin
Cov analogue yog kim dua los ntawm 53 rubles.
Chaw tsim tshuaj paus: Merck Sante SAA.S. (Fab Kis)
Cov Ntawv Tso Tawm:
- Ntsiav tshuaj 500 mg, 30 pcs., Nqe los ntawm 110 rubles
- Ntsiav tshuaj 1000 mg, 30 pcs., Nqe los ntawm 185 rubles
Cov lus qhia rau kev siv
Fab kis tshuaj kho tus mob ntshav qab zib hom 2. Muag hauv cov ntsiav tshuaj muaj txog 500 txog 1000 mg ntawm metformin ua cov tshuaj tiv thaiv kab mob ib leeg. Muaj contraindications, yog li ntawd, ua ntej noj Glucofage, nws yog qhov yuav tsum tau sab laj nrog tus kws tshaj lij.
Cov analogue kim dua los ntawm 52 rubles.
Chaw tsim tshuaj paus: Akrikhin (Russia)
Cov Ntawv Tso Tawm:
- Ntsiav tshuaj 500 mg, 60 pcs., Nqe los ntawm 109 rubles
- Ntsiav tshuaj 850 mg, 60 pcs., Nqe los ntawm 190 rubles
Cov lus qhia rau kev siv
Gliformin yog tshuaj siv hauv tsev rau kev kho mob ntshav qab zib hom 2. Muag rau hauv cov qauv ntawm cov ntsiav tshuaj nrog metformin ua tus tsuas ua hauj lwm (noj ntau npaum li 250 lossis 500 mg yog ua tau). Gliformin muaj cov npe loj tshaj plaws ntawm contraindications, yog li ua ntej pib kev kho mob, nco ntsoov nyeem cov lus qhia ntawm kev ua haujlwm rau kev siv.
Cov analogue ntau kim dua los ntawm 119 rubles.
Chaw tsim tshuaj paus: Vörwag Pharma GmbH & Co. KG (Lub Teb Chaws Yelemees)
Cov Ntawv Tso Tawm:
- Ntsiav tshuaj 1000 mg, 30 pcs., Nqe los ntawm 176 rubles
- Ntsiav tshuaj 850 mg, 60 pcs., Nqe los ntawm 190 rubles
Cov lus qhia rau kev siv
Lwm cov tshuaj rau ntshav qab zib hauv cov ntsiav tshuaj tso tawm. Muag hauv cov thawv muag khoom ntawm 30 ntsiav tshuaj uas muaj metformin hydrochloride ua cov khoom xyaw ua zaub mov. Contraindicated thaum cev xeeb tub thiab pub niam mis.
Cov analogue ntau kim dua los ntawm 121 rubles.
Chaw tsim tshuaj paus: Hemofarm A.D. (Serbia)
Cov Ntawv Tso Tawm:
- Tab. 500 mg, 60 pcs., Nqe txij li 178 rubles
- Ntsiav tshuaj 850 mg, 60 pcs., Nqe los ntawm 190 rubles
Cov lus qhia rau kev siv
Metformin yog ib qho tshuaj Serbian hypoglycemic rau kev siv sab hauv. Cov tshuaj muaj pes tsawg leeg ntawm cov ntsiav tshuaj muaj cov khoom xyaw nquag ntawm tib lub npe hauv tshuaj ntau npaum 500 lossis 850 mg. Nws yog tshuaj rau kev kho mob ntshav qab zib hom 2 (hauv cov neeg laus), tshwj xeeb yog cov muaj rog.
Cov analogue ntau kim dua los ntawm 214 rubles.
Chaw tsim tshuaj paus: Berlin-Chemie / Menarini Pharma GmbH (Lub Teb Chaws Yelemees)
Cov Ntawv Tso Tawm:
- Tab. 500 mg, 60 pcs., Nqe txij li 271 rubles
- Ntsiav tshuaj 850 mg, 60 pcs., Nqe los ntawm 190 rubles
Cov lus qhia rau kev siv
Siofor yog kev npaj cov tshuaj Germanic npaj rau kev kho mob hom 2 ntshav qab zib mellitus. Metformin hydrochloride hauv kev siv tshuaj ntau npaum li 500 txog 1000 mg yog siv los ua cov tshuaj ntxiv. Muag hauv cov thawv muaj 60 ntsiav tshuaj.
Analogs hauv kev muaj pes tsawg leeg thiab qhia txog kev siv
| Npe | Nqe hauv Lavxias | Nqe hauv Ukraine |
|---|---|---|
| Bagomet Metformin | -- | 30 UAH |
| Glucofage metformin | 12 RUB | 15 UAH |
| Globophage xr metformin | -- | 50 UAH |
| Reduxin Met Metformin, Sibutramine | 20 RUB | -- |
| Dianormet | -- | 19 UAH |
| Diaformin metformin | -- | 5 UAH |
| Metformin metformin | 13 RUB | 12 UAH |
| Tshuaj Metformin sandoz metformin | -- | 13 UAH |
| Siofor | 208 rub | 27 UAH |
| Formin metformin hydrochloride | -- | -- |
| Emnorm EP Metformin | -- | -- |
| Megifort Metformin | -- | 15 UAH |
| Tshuaj hlau Metformin | -- | 20 UAH |
| Tshuaj Metamin SR Metformin | -- | 20 UAH |
| Metfogamma metformin | 256 rub | 17 UAH |
| Tefor metformin | -- | -- |
| Glycometer | -- | -- |
| Glycomet SR | -- | -- |
| Metformin Canon metformin, ovidone K 90, pob kws hmoov txhuv, crospovidone, magnesium stearate, talc | 26 RUB | -- |
| Insuffor metformin hydrochloride | -- | 25 UAH |
| Metformin-teva metformin | 43 txhuam | 22 UAH |
| Diaformin SR metformin | -- | 18 UAH |
| Mepharmil Metformin | -- | 13 UAH |
| Metformin Yawg Liaj Ua Teb Metformin | -- | -- |
Cov npe saum toj no ntawm cov yeeb tshuaj analogues, uas qhia formethine hloov chaw, yog qhov tsim nyog tshaj plaws vim tias lawv muaj tib cov tshuaj sib luag thiab sib luag ua ke raws li kev taw qhia rau kev siv
Sib txawv muaj pes tsawg leeg, tuaj yeem ua ke nyob rau hauv kev taw qhia thiab cov qauv ntawm daim ntawv thov
| Npe | Nqe hauv Lavxias | Nqe hauv Ukraine |
|---|---|---|
| Avantomed rosiglitazone, metformin hydrochloride | -- | -- |
| Glibenclamide Glibenclamide | 30 RUB | 7 UAH |
| Maninyl Glibenclamide | 54 rub | 37 UAH |
| Glibenclamide-Health Glibenclamide | -- | 12 UAH |
| Glyurenorm glycidone | 94 rub | 43 UAH |
| Bisogamma Glyclazide | 91 rub | 182 UAH |
| Glidiab Glyclazide | 100 tshiav | 170 UAH |
| Lawj Xeeb MR | -- | 92 UAH |
| Kev kuaj mob mr Gliclazide | -- | 15 UAH |
| Glidia MV Gliclazide | -- | -- |
| Glykinorm Gliclazide | -- | -- |
| Gliclazide Gliclazide | 231 rub | 44 UAH |
| Glyclazide 30 MV-Indar Glyclazide | -- | -- |
| Glyclazide-Kev Noj Qab Haus Huv Gliclazide | -- | 36 UAH |
| Glioral Glyclazide | -- | -- |
| Kev kuaj mob Gliclazide | -- | 14 UAH |
| Diazide MV Gliclazide | -- | 46 UAH |
| Osliklid Gliclazide | -- | 68 UAH |
| Diadeon gliclazide | -- | -- |
| Glyclazide MV Gliclazide | 4 RUB | -- |
| Amaril | 27 RUB | 4 UAH |
| Glemaz glimepiride | -- | -- |
| Glian glimepiride | -- | 77 UAH |
| Glimepiride Glyride | -- | 149 UAH |
| Glimepiride diapiride | -- | 23 UAH |
| Thaj neeb | -- | 12 UAH |
| Glimax glimepiride | -- | 35 UAH |
| Glimepiride-Lugal glimepiride | -- | 69 UAH |
| Av nplaum glimepiride | -- | 66 UAH |
| Diabrex glimepiride | -- | 142 UAH |
| Meglimide glimepiride | -- | -- |
| Melpamide Glimepiride | -- | 84 UAH |
| Perinel glimepiride | -- | -- |
| Glempid | -- | -- |
| Raug Tsim | -- | -- |
| Glimepiride glimepiride | 27 RUB | 42 UAH |
| Glimepiride-teva glimepiride | -- | 57 UAH |
| Glimepiride Canon glimepiride | 50 RUB | -- |
| Glimepiride Pharmstandard glimepiride | -- | -- |
| Dimaril glimepiride | -- | 21 UAH |
| Glamepiride diamerid | 2 RUB | -- |
| Amaryl M Limepiride Micronized, Metformin Hydrochloride | 856 rub | 40 UAH |
| Glibomet glibenclamide, metformin | 257 rub | 101 UAH |
| Glucovans glibenclamide, metformin | 34 RUB | 8 UAH |
| Dianorm-m Glyclazide, Metformin | -- | 115 UAH |
| Dibizid-m glipizide, metformin | -- | 30 UAH |
| Douglimax glimepiride, metformin | -- | 44 UAH |
| Duotrol glibenclamide, metformin | -- | -- |
| Gluconorm | 45 rub | -- |
| Glibofor metformin hydrochloride, glibenclamide | -- | 16 UAH |
| Avandamet | -- | -- |
| Avandaglim | -- | -- |
| Janumet metformin, sitagliptin | 9 RUB | 1 UAH |
| Velmetia metformin, sitagliptin | 6026 rub | -- |
| Galvus Met vildagliptin, metformin | 259 RUB | 1195 UAH |
| Tripride glimepiride, metformin, pioglitazone | -- | 83 UAH |
| Comboglize XR metformin, saxagliptin | -- | 424 UAH |
| Comboglyz Prolong metformin, saxagliptin | 130 rub | -- |
| Gentadueto linagliptin, metformin | -- | -- |
| Vipdomet metformin, alogliptin | 55 RUB | 1750 UAH |
| Sinjardi empagliflozin, metformin hydrochloride | 240 rub | -- |
| Voglibose Oxide | -- | 21 UAH |
| Glutazone pioglitazone | -- | 66 UAH |
| Dropia Sanovel pioglitazone | -- | -- |
| Januvia sitagliptin | 1369 rub | 277 UAH |
| Galvus vildagliptin | 245 RUB | 895 UAH |
| Onglisa saxagliptin | 1472 RUB | 48 UAH |
| Nesina alogliptin | -- | -- |
| Vipidia alogliptin | 350 rub | 1250 UAH |
| Trazhenta linagliptin | 89 rub | 1434 UAH |
| Lixumia lixisenatide | -- | 2498 UAH |
| Guarem Guar cob | 9950 rub | 24 UAH |
| Insvada repaglinide | -- | -- |
| Novonorm Repaglinide | 30 RUB | 90 UAH |
| Cov Chaw Tshaj Tawm Repaglinide | -- | -- |
| Baeta Exenatide | 150 rub | 4600 UAH |
| Baeta Ntev Exenatide | 10248 rub | -- |
| Viktoza liraglutide | 8823 rub | 2900 UAH |
| Saxenda liraglutide | 1374 rub | 13773 UAH |
| Forksiga Dapagliflozin | -- | 18 UAH |
| Forsiga Dapagliflozin | 12 RUB | 3200 UAH |
| Invocana canagliflozin | 13 RUB | 3200 UAH |
| Jardins Empagliflozin | 222 RUB | 566 UAH |
| Trulicity Dulaglutide | 115 RUB | -- |
Yuav ua li cas thiaj nrhiav tau qhov pheej yig tshuaj ntawm cov tshuaj kim?
Txhawm rau kom pom qhov pheej yig cov khoom sib piv rau cov tshuaj, cov dav dav lossis cov lus sau, ua ntej txhua yam peb pom zoo kom them sai sai rau qhov muaj pes tsawg leeg, uas yog rau tib cov tshuaj nquag thiab qhia tau rau kev siv. Cov tshuaj sib xyaw zoo ib yam ntawm cov tshuaj yuav qhia tau tias cov tshuaj cuam tshuam nrog cov tshuaj, kws tshuaj sib npaug lossis chaw muag tshuaj. Txawm li cas los xij, tsis txhob hnov qab txog qhov ua tsis muaj zog ntawm cov tshuaj uas zoo sib xws, uas tuaj yeem cuam tshuam kev nyab xeeb thiab ua haujlwm. Tsis txhob hnov qab txog cov lus qhia ntawm cov kws kho mob, kev noj tshuaj rau nws tus kheej tuaj yeem tsim kev puas tsuaj rau koj kev noj qab haus huv, yog li nco ntsoov sab laj nrog koj tus kws kho mob ua ntej siv cov tshuaj.
Zoo thaj chaw ntawm lub ntsiav tshuaj npaj
Cov cim tseem ceeb rau kev siv cov tshuaj xws li hauv qab no:
- muaj cov tsos mob metabolic lossis cov tsos mob ntawm cov tshuaj insulin kuj,
- raws li txoj cai, nyob rau hauv muaj cov tshuaj tiv thaiv insulin, kev rog yog sai sai sai hauv cov neeg mob, vim qhov tshwm sim ntawm metformin thiab kev saib xyuas ntawm kev noj zaub mov tshwj xeeb, maj mam poob phaus tuaj yeem ua tiav,
- yog tias muaj kev ua txhaum cov piam thaj hauv kev siab ntev,
- kev txhim kho kab mob hu ua Cleopolycystic,
- insulin-tiv thaiv cov ntshav qab zib mellitus raws li kev kho mob lossis kho txoj hauv kev,
- mob ntshav qab zib insulin-nyob rau hauv daim ntawv ua ke nrog insulin los.
Yog tias peb sib piv cov tshuaj Formmetin nrog lwm cov tshuaj ua kom ntshav qab zib, cov ntsiab lus tseem ceeb ntawm metformin yuav tsum raug hais qhia:
- Nws cov nyhuv txo qis insulin tsis kam rau hauv tus neeg mob. Metformin hydrochloride muaj peev xwm ua kom lub hlwb thiab cov nqaij mob ntau ntxiv rau cov kua nplaum tsim tawm los ntawm cov txiav.
- Noj tshuaj yog nrog nws txoj kev nqus ntawm cov hnyuv hauv lub plab zom mov. Yog li, ua kom qeeb ntawm kev nqus ntawm cov piam thaj los ntawm txoj hnyuv yog tiav.
- Yuav pab tau inhibit daim siab gluconeogenesis, thiaj li hu ua tiav txheej txheem ntshav qabzib.
- Nws pab txo kev qab los noj mov, uas yog qhov tshwj xeeb tshaj yog rau cov neeg mob ntshav qab zib.
- Nws muaj cov txiaj ntsig zoo ntawm cov roj cholesterol, txo qhov tsis zoo thiab nce qhov zoo.
Tsis tas li ntawd, cov tshuaj pab ua kom nruab nrab cov txheej txheem ntawm peroxidation cov rog.
Cov lus qhia rau kev siv ntsiav tshuaj
Cov lus qhia qauv rau kev siv muaj qhov hais tias cov tshuaj muaj nyob rau hauv cov ntsiav tshuaj hauv daim ntawv ntawm cov tshuaj biconvex dawb.
Cov tshuaj muaj pes tsawg leeg suav nrog cov tshuaj nquag hu ua Metformin hydrochloride thiab ntu sib xyaw hauv cov tshuaj magnesium stearate, povidone thiab croscarmellose sodium.
Cov tshuaj hauv qab no hauv qab no yog nthuav tawm ntawm lub khw muag tshuaj - 0.5 g, 0.85 g thiab 1 g ntawm cov tshuaj nquag. Ua raws li qhov mob hnyav ntawm hyperglycemia, ib tus kws kho mob tshaj tawm txoj kev noj tshuaj kom tsim nyog. Tag nrho cov formin ntsiav tshuaj tuaj yeem yuav hauv cov thawv ntawm 30, 60 lossis 120 daim. Lawv siv tau tsuas yog tsim nyog los ntawm tus kws kho mob koom nrog (niaj hnub no ntau tus poj niam siv txhais tau tias hauv kev poob phaus).
Cov txheej txheem ntawm kev tswj hwm thiab kev noj tshuaj yog tsim rau txhua tus neeg mob ib tus zuj zus, raws li cov kev ntsuas:
- Qhov loj ntawm cov kab mob pathology thiab theem ntawm cov piam thaj nyob hauv cov ntshav ꓼ
- tus luj neeg mob thiab nyoog
- muaj nyob ntawm concomitant kab mob.
Ua ntej pib txoj kev kho mob, nws raug nquahu kom muaj kev kuaj mob tsim nyog thiab ntsuas kev soj ntsuam los txiav txim siab cov kev pheej hmoo thiab tshwm sim ntawm kev tsis zoo thaum siv tshuaj.
Cov tshuaj Formmetin, raws li txoj cai, raug ua raws li cov phiaj xwm hauv qab no:
- Qhov ncauj tom qab noj mov, haus dej kom ntau.
- Pib kev kho mob yuav tsum pib nrog kev noj tsawg kawg ntawm cov tshuaj nquag thiab yuav tsum tsib puas milligrams ib hnub.
- Thaum kawg lub sijhawm (feem ntau yog tom qab ob lub limtiam), tus kws kho mob mus koom, nyob ntawm cov txiaj ntsig ntawm kev tshuaj ntsuam thiab cov piam thaj hauv cov ntshav, txiav txim siab txog kev hloov pauv ntau npaum li cas ntawm cov tshuaj. Nws yuav tsum tau yug los hauv lub siab tias qhov nruab nrab cov tshuaj txhua hnub nws txawv ntawm 500 mus rau 1000 mg ntawm cov tshuaj nquag metformin hydrochloride.
- Kev siv ntau tshaj plaws ntawm kev siv tshuaj ntsiav ib hnub yuav tsum tsis pub tshaj 3000 mg ntawm cov tshuaj nquag, rau cov neeg laus cov duab no yog 1000 mg.
Koj tuaj yeem noj tshuaj formin ib zaug lossis ob peb zaug hauv ib hnub, nyob ntawm cov koob tshuaj uas tau tsim tseg.
Yog hais tias tus neeg mob xav tau ntau ntawm cov tshuaj, nws yog qhov zoo dua rau kev tso nws qhov kev nqus tsawg zaug hauv ib hnub.
Cov kev xav tsis zoo ntawm ib qho tshuaj
Cov tshuaj muaj peev xwm cuam tshuam rau lub cev, ua kom pom nws cov kev tsis zoo nyob rau hauv daim ntawv ntawm cov kev mob tshwm sim.
Txhawm rau kom txo qis kev pheej hmoo ntawm lawv tshwm sim, nws yog ib qhov tsim nyog yuav tsum ua raws txhua cov lus qhia ntawm tus kws kho mob tshwj xeeb.
Nws kuj tseem pom zoo tias koj yuav tsum paub koj tus kheej nrog cov ntaub ntawv ntawm lub ntim ntxig.
Qhov tseem ceeb tsis zoo tshwm sim uas yuav tshwm sim los ntawm kev noj cov tshuaj Formmetin, tsis hais noj ntau npaum li cas, suav nrog:
- kev tshwm sim ntawm ntau yam teeb meem nrog txoj hnyuv plab hnyuv. Cov no yog, ua ntej tshaj plaws, cov tsos mob xws li xeev siab thiab ntuav, raws plab, tsam plab thiab mob hauv plab
- tshuaj ua rau muaj kev pheej hmoo ntawm qhov tsis nco qab
- ib qho kev hloov pauv ntawm qhov kev hnov qab saj yog qhov ua tau, uas tau tshwm sim los ntawm qhov tshwm sim ntawm qhov tsis kaj siab tom qab ntawm cov hlau hauv qhov ncauj kab noj hniav ꓼ
- qhov kev txo qis hauv cov vitamin B, yuam kom koj noj tshuaj ntxiv nrog rau cov tshuaj ntxiv
- kev nthuav dav ntawm anemiaꓼ
- nrog ib qho tseem ceeb noj ntau dhau, nws yuav muaj kev pheej hmoo ntawm hypoglycemiaꓼ
- muaj teeb meem ntawm daim tawv nqaij, yog tias muaj kev ua kom tshwm sim ntawm kev tsis haum tshuaj rau kev siv tshuaj.
Qee tus neeg mob pom tias cov tshuaj formin yog tshuaj tua kab mob. Qhov tseeb, ib hom tshuaj tsis yog rau ib pawg tshuaj ntawd. Tib lub sijhawm, rau menyuam yaus, kev siv tshuaj kho mob kom tshem tawm hyperglycemia yog txwv tsis pub.
Cov kev mob tshwm sim tuaj yeem tshwm sim los ntawm kev siv tshuaj tsis raug cai lossis nrog rau kev siv tus kheej. Ua ke nrog Daim Ntawv Foos nrog rau lwm cov khoom siv kho mob (hauv daim ntawv ntawm cov ntsiav tshuaj, ncua kev kawm, kev txhaj tshuaj ntawm ntau cov chav kawm thiab pab pawg) yog ua tau tsuas yog kev tso cai ntawm tus kws kho mob tshwj xeeb.
Cov kev txwv tsis pub siv rau kev siv tshuaj yog dab tsi?
Cov tshuaj xyaw cov tshuaj tiv thaiv kab mob yog qhia hauv daim ntawv me me rau kev npaj ua ntsiav.
Cov neeg tsim khoom tshaj tawm rau tag nrho cov neeg siv khoom muaj peev xwm hauv kev nthuav dav txog cov mob uas tsis tsim nyog siv cov tshuaj.
Ib qho ntxiv, cov lus qhia tseem muaj cov ntaub ntawv uas formmetin tau sib haum nrog cov tshuaj thiab tshuaj twg.
Nws yog txwv tsis pub noj tshuaj yog tias cov xwm txheej hauv qab no raug txheeb xyuas:
- Acidosis nyob rau hauv cov mob huam los yog mob ntev.
- Cov ntxhais thaum lub sijhawm ua menyuam lossis pub mis niam.
- Cov neeg mob uas muaj hnub nyoog so, tshwj xeeb tshaj yog tom qab rau caum tsib xyoos.
- Intolerance rau cov tshuaj tiv thaiv, txij li thaum txoj kev loj hlob ntawm kev tsis haum tshuaj hnyav tau muaj.
- Yog tias tus neeg mob kuaj tau lub plawv tsis ua haujlwm.
- Nrog rau lub plawv nres dhau los ua ntshav qab zib.
- Yog tias muaj hypoxia tshwm sim.
- Thaum lub cev qhuav dej, uas tuaj yeem tshwm sim los ntawm ntau yam kab mob sib kis.
- Kev siv lub cev ntau dhau.
- Cov kab mob ntawm lub plab, nrog rau qhov muaj mob ntawm qhov mob.
- Daim siab ua haujlwm.
Ntxiv rau, kev sib txuam ntawm kev kho mob nrog cawv (haus dej cawv hauv ib qho kev nthuav qhia) tsis tuaj yeem lees txais.
Yog tias tus neeg mob lub raum ua haujlwm, txoj kev pheej hmoo ntawm kev mob lactic acidosis yuav nce ntxiv, txij li ntau qhov tseem ceeb ntawm cov kab mob lactic acid hauv lub cev pib nce ntau.
Kev tshuaj xyuas ntawm cov kws khomob tshwjxeeb thiab cov neeg mob thiab mob piv txwv
Cov lus piav qhia ntawm cov tshuaj formulations Formin thiab cov neeg siv khoom lag luam ntau txheeb xyuas nws qhov ua tau zoo.
Tsis tas li ntawd, feem ntau cov neeg mob qhia tias yooj yim thev taus ntawm cov tshuaj thiab qhov tsis muaj ntau yam tshwm sim.
Formmetin muaj tus nqi hauv cov chaw muag tshuaj ntawm ib puas rubles thiab nyob ntawm ntau yam.
Qhov tseeb uas cuam tshuam tus nqi ntawm cov tshuaj muaj raws li nram no:
- cov naj npawb ntawm cov ntsiav tshuaj ib pobꓼ
- tsuas tshuaj ntawm cov nquag tshuaj ꓼ
- nroog muag thiab chaw muag tshuaj.
Tus nqi ntawm formin yog ib qho kev txiav txim ntawm qhov ntau tsawg dua lwm cov tshuaj uas muaj cov tshuaj ua kom nquag plias metformin hydrochloride. Vim li ntawd, feem ntau cov kws kho mob tshwj xeeb pom zoo siv cov cuab yeej no los kho kev mob glycemia hauv ntshav qab zib. Cov kws kho mob cov lus hais txog cov txiaj ntsig zoo ntawm qib ntawm cov piam thaj hauv cov ntshav, kev nruab nrab ntawm kev txhim kho ntawm kev tiv thaiv cov tshuaj insulin, tso cai rau peb xaus lus tias Formmetin yog qhov tseeb ntawm kev xaiv nyiaj txiag uas coj tau cov txiaj ntsig zoo.
Formimetin analogues hauv khw pharmacological yog sawv cev hauv ntau. Cov no suav nrog cov tshuaj tsis raug thiab cov tshuaj sib kis, uas tej zaum yuav muaj sib txawv, tab sis muaj cov nyhuv zoo sib xws. Thaum tshawb nrhiav qhov hloov chaw, koj yuav tsum xub nrhiav tswv yim los ntawm koj tus kws kho mob uas tuaj yeem pom zoo rau qhov kev xaiv tsim nyog tshaj plaws.
Cov tshuaj hauv qab no yog suav nrog tus lej ntawm Formmetin analogs:
Tag nrho cov tshuaj saum toj no yog nyob rau hauv cov ntsiav tshuaj muaj piam thaj nrog lub txiaj ntsig hypoglycemic. Cov khoom siv tseem ceeb yog metformin hydrochloride. Xws li cov tshuaj yeeb yaj kiab tsis txawv ntawm Formine. Qhov sib txawv tej zaum yuav muaj nyob rau hauv tus naj npawb ntawm kev phiv los sis contraindications pom, nrog rau tus nqi ntawm cov tshuaj.
Qee zaum, formin raug tso cai ua kev kho mob sib xyaw nrog kev siv tshuaj xws li atorvastatin lossis glycine.
Cov tshuaj dab tsi rau ntshav qab zib yuav pab ua kom cov ntshav qab zib nyob li qub, tus kws tshaj lij yuav qhia hauv video hauv kab lus no.
Formmetin: cov lus qhia rau kev siv, tus nqi, analogues
Formmetin yog ib hom tshuaj uas nquag ua ntawm metformin hydrochloride. Muab koob tshuaj: 0.5 g, 0.85 g lossis 1 g. Cov lus piv txwv: Gliformin, Metadiene, Nova Met, NovoFormin, Siofor, Sofamet.
Ntu cov khoom siv: croscarmellose sodium, nruab nrab molecular hnyav povidone (polyvinylpyrrolidone), magnesium stearate rau kev lag luam kws tshuaj.
Daim ntawv tso tawm: puag ncig tiaj-cylindrical dawb ntsiav tshuaj nrog lub ntsej muag thiab qhov pheej hmoo (ntau npaum li 0.5 g) thiab oval biconvex dawb ntsiav tshuaj nrog kev pheej hmoo ntawm ib sab (ntau npaum li cas ntawm 0.85 g thiab 1.0 g).
Cov cim Pharmacological
Formethine txo qis kev nqus ntawm cov piam thaj hauv txoj hnyuv, inhibits cov txheej txheem ntawm gluconeogenesis nyob rau hauv daim siab, txhim kho peripheral qabzib tso zis, thiab nce rhiab ntawm cov ntaub so ntswg mus rau insulin npaj.
Hauv qhov no, formetin:
- Nws tsis cuam tshuam rau tsim cov tshuaj insulin los ntawm beta hlwb nyob hauv txoj kev txiav
- Tsis cuam tshuam qhov kev txhim kho ntawm lub xeev hypoglycemic.
- Txo cov lej lipoproteins uas tsis muaj ntau thiab triglycerides hauv cov ntshav.
- Txo cov rog dhau, tswj lub cev nyhav.
- Nws muaj cov nyhuv fibrinolytic vim yog kev tsuj tawm ntawm cov nqaij mos plasminogen activator.
Formaline, tom qab tswj hwm ntawm qhov ncauj, maj mam nqus tawm ntawm txoj hnyuv hauv plab. Tus nqi ntawm cov khoom lag luam bioavailable tom qab siv cov koob tshuaj yog kwv yees li 60%.
Qhov siab tshaj plaws ntawm cov tshuaj hauv cov ntshav tshwm sim 2.5 teev tom qab siv sab hauv.
Cov tshuaj ntshav yuav luag tsis khi rau cov ntshav plasma, ua kom lub siab, lub raum, leeg, cov qog thiab lub cev tawm ntawm lub raum ua ib daim ntawv tsis tau hais txog. Ib nrab-lub neej ntawm cov tshuaj yog 1.5 - 4.5 teev.
Ua tib zoo mloog! Yog hais tias tus neeg mob ua rau lub raum tsis zoo, kev ua kom muaj cov tshuaj hauv lub cev yog qhov ua tau.
Kev ntsuas rau siv
Cov tshuaj yog tawm rau hom 2 mob ntshav qab zib mellitus, thaum kev noj zaub mov noj tsis tau coj cov txiaj ntsig zoo (hauv cov neeg mob rog rog), txhua qhov no tau qhia los ntawm cov tshuaj cov lus qhia.
Qhov ntau thiab tsawg ntawm cov tshuaj yog kws kho mob sau tseg los ntawm tus kheej rau txhua tus neeg mob. Qhov sib txawv ntawm cov tshuaj yog vim muaj qhov concentration ntawm cov piam thaj hauv cov ntshav. Cov tshuaj xyaw ntshav yuav tsum noj thaum lub sijhawm lossis tom qab tus neeg mob tau noj zaub mov, tsis tas yuav zom thiab haus ntau qhov dej.
Nyob rau thawj theem ntawm kev kho mob, lub koob yuav tsum yog 0.85g. 1 zaug hauv ib hnub lossis 0.5g. 1-2 zaug ib hnub. Maj mam ntxiv qhov koob rau 3g. ib hnub.
Tseem Ceeb! Rau cov neeg laus laus, qhov niaj hnub yuav tsum tsis pub tshaj 1g. Vim tias muaj kev pheej hmoo siab ntawm cov kab mob lactic acidosis, nrog rau cov kab mob hnyav ntawm lub cev loj heev, cov koob tshuaj yuav tsum tau txo.
Cov lus qhia tshwj xeeb rau kev siv
Cov lus qhia: thaum kho, koj yuav tsum siv dag zog kom tswj lub raum kev ua haujlwm. Ib zaug txhua rau lub hlis thiab nrog qhov kev txhim kho ntawm myalgia, nws yog qhov tsim nyog los txiav txim qhov nyiaj ntawm lactate hauv lub ntshav.
Formmetin yuav raug siv ua ke nrog sulfonylurea derivatives. Hauv qhov no, ua tib zoo saib xyuas cov ntshav qab zib kom tsawg.
Formetin thaum lub sij hawm monotherapy tsis cuam tshuam rau lub peev xwm los ua haujlwm nrog cov txheej txheem nyuaj thiab tsav tsheb. Yog tias cov tshuaj no ua ke nrog lwm cov tshuaj hypoglycemic, txoj kev txhim kho hypoglycemia yog qhov yuav tsum tau, uas tsis muaj peev xwm tsav lub tsheb thiab ua haujlwm nrog cov txheej txheem nyuaj uas yuav tsum muaj kev kub siab ntawm kev mloog.
Kev phiv tshuaj
Los ntawm lub plab zom mov:
- nws yog xim hlau saj
- xeev siab, ntuav,
- flatulence, raws plab,
- tsis qab los noj mov
- mob plab.
Los ntawm hemopoietic plab hnyuv siab raum nyob rau qee kis megalobast anemia.
Hais txog kev siv metabolism:
- xav tau kev tsum tsis ua tiav ntawm kev kho mob, lactic acidosis muaj tsawg,
- nrog rau kev kho mob ntev, hypovitaminosis B12 tsim.
Cov tshuaj endocrine ntawm cov tshuaj txhaj tsis txaus tuaj yeem teb nrog hypoglycemia.
Kev ua xua rau: tawv nqaij ua pob.
Kev cuam tshuam nrog lwm yam tshuaj
Cov nyhuv ntshav hypoglycemic ntawm metformin tej zaum yuav ua kom zoo dua thaum siv ua ke nrog:
- tshuaj insulin
- sulfonylurea derivatives,
- oxytetracycline
- acarbose
- cov tshuaj uas tsis yog tshuaj steroidal los kho,
- cyclophosphamide
- angiotensin hloov mus rau enzyme inhibitors,
- monoamine oxidase inhibitors
- β-blockers
- derivatives ntawm clofibrate.
Kev txo qis hauv cov nyhuv ntawm hypoglycemic ntawm metformin yog pom nrog kev siv ua ke nrog:
- “Ntxees” thiab thiazide diuretics,
- tshuaj tiv thaiv qhov ncauj
- glucocorticosteroids,
- glucagon
- epinephrine
- phenothiazine derivatives,
- sympathomimetics
- nicotinic acid derivatives,
- cov thyroid hormones.
Cov Yuav Tsum Tau Ua
Koj tsis tuaj yeem nqa tshuaj formin nrog:
- mob raum tsis zoo,
- ketoacidosis uas mob ntshav qab zib, precoma, coma,
- ua pa thiab lub plawv tsis ua haujlwm,
- lub cev qhuav dej
- cov kev huam yuaj ntawm cerebrovascular,
- kev haus cawv qaug cawv thiab lwm yam mob uas ua rau muaj txiaj ntsig lactic acidosis,
- thaum cev xeeb tub thiab lactation,
- muaj lub cev tsis haum rau lub tshuaj,
- kev raug mob thiab raug phais mob hnyav,
- cov kab mob kis hnyav
- qaug cawv ua rau qaug cawv,
- lactic acidosis.
Cov lus qhia nrog hais tias kev siv Formetin yuav tsum tsis txhob muaj ua ntej los ntawm kev tshawb fawb radiological thiab radioisotope nrog kev qhia ntawm kev sib piv ntawm iodine uas muaj nyob hauv 2 hnub.
Cov tshuaj Formethine tsis pom zoo siv rau cov neeg laus dua 60 xyoo uas ua hauj lwm hnyav. Yog tias tsis tau ua raws li txoj cai no, cov neeg mob zoo li no yuav ua mob lactic acidosis.
Qhov kev qhia ntawv noj ntau tshaj hais li cas
Cov lus qhia rau cov tshuaj Formmetin ceeb toom tias nrog ib qho kev noj ntau dhau, muaj peev xwm tsim tau cov kab mob lactic acidosis nrog rau kev tuag taus. Qhov ua rau tus mob no yuav yog tsub zuj zuj ntawm cov tshuaj nyob rau hauv lub cev vim qhov ua rau lub raum khiav tsis zoo.
Cov tsos mob hauv qab no yog thawj cov tsos mob ntawm tus kab mob lactic acidosis:
- Xeev siab, ntuav.
- Raws plab, mob plab.
- Tsis muaj zog, lub cev tsis muaj zog.
- Kiv taub hau
- Mob leeg mob.
- Reflex bradyarrhythmia.
- Txo cov ntshav siab.
- Tsis nco qab nco qab thiab kev loj hlob ntawm coma
Yog hais tias tus neeg mob muaj cov cim tseem ceeb ntawm cov kab mob lactic acidosis, Formin yuav tsum tau muab tshem tawm tam sim ntawd los ntawm kev ntsuas kho mob, tus neeg mob yuav tsum maj nrawm mus rau lub tsev kho mob uas tus kws kho mob tuaj yeem txiav txim siab txog kev tsim kho ntawm lactate thiab ua rau kev kuaj mob tsis meej pem.
Ib txoj hauv kev zoo tshaj plaws ntawm kev tshem tawm cov tshuaj metformin thiab lactate los ntawm lub cev yog hemodialysis, nrog rau kev kho cov tsos mob twg.
Tsim qauv - chaw cia khoom, nqe
Txee lub neej ntawm cov tshuaj yog 24 lub hlis, tom qab ntawd Formetin tsis tuaj yeem siv. Cov tshuaj zwm rau cov ntawv sau B. Nws yuav tsum tau muab cia rau hauv qhov chaw tsaus rau cov me nyuam nkag tsis tau ntawm qhov kub thiab txias tsis siab tshaj 25 ° C.
Daim ntawv tso tawm - ntsiav tshuaj ntawm 850 mg. 60 daim.
Daim ntawv tso tawm - ntsiav tshuaj 1gr. 60 daim.
Qee cov qauv siv kuj kim dua.
Tshuaj qhov ncauj hypoglycemic
Tso tawm daim ntawv, muaj pes tsawg leeg thiab ntim khoom
Ntsiav tshuaj dawb, puag ncig, tiaj cylindrical, nrog bevel thiab nqis siab tshaj.
| 1 tab | |
| metformin hydrochloride | 0.5 g |
Cov tub ntxhais: povidone (nruab nrab molecular phaus polyvinylpyrrolidone, povidone K-30) - 0.017 g, croscarmellose sodium (primellose) - 0.008 g, magnesium stearate - 0.005 g.
10 Pcs. - blister packagings (6) - pob ntawv ntawm cardboard
Ntsiav tshuaj dawb, puag ncig, tiaj cylindrical, nrog bevel thiab nqis siab tshaj.
| 1 tab | |
| metformin hydrochloride | 0.5 g |
Cov tub ntxhais: povidone (nruab nrab molecular phaus polyvinylpyrrolidone, povidone K-30) - 0.017 g, croscarmellose sodium (primellose) - 0.008 g, magnesium stearate - 0.005 g.
10 Pcs. - blister packagings (6) - pob ntawv ntawm cardboard.
Ntsiav tshuaj dawb, oval, biconvex, nrog kev thais ntawm ib sab.
| 1 tab | |
| metformin hydrochloride | 0.85 g |
Cov tub ntxhais: povidone (nruab nrab molecular phaus polyvinylpyrrolidone, povidone K-30) - 0.029 g, croscarmellose sodium (primellose) - 0.0136 g, magnesium stearate - 0.0084 g.
10 Pcs. - blister packagings (6) - pob ntawv ntawm cardboard.
Ntsiav tshuaj dawb, oval, biconvex, nrog kev thais ntawm ib sab.
| 1 tab | |
| metformin hydrochloride | 0.85 g |
Cov tub ntxhais: povidone (nruab nrab molecular phaus polyvinylpyrrolidone, povidone K-30) - 0.029 g, croscarmellose sodium (primellose) - 0.0136 g, magnesium stearate - 0.0084 g.
10 Pcs. - blister packagings (6) - pob ntawv ntawm cardboard.
Ntsiav tshuaj dawb, oval, biconvex, nrog kev thais ntawm ib sab.
| 1 tab | |
| metformin hydrochloride | 1 g |
Cov tub ntxhais: povidone (nruab nrab molecular phaus polyvinylpyrrolidone, povidone K-30) - 0.034 g, croscarmellose sodium (primellose) - 0.016 g, magnesium stearate - 0.01 g.
10 Pcs. - blister packagings (6) - pob ntawv ntawm cardboard.
Ntsiav tshuaj dawb, oval, biconvex, nrog kev thais ntawm ib sab.
| 1 tab | |
| metformin hydrochloride | 1 g |
Cov tub ntxhais: povidone (nruab nrab molecular phaus polyvinylpyrrolidone, povidone K-30) - 0.034 g, croscarmellose sodium (primellose) - 0.016 g, magnesium stearate - 0.01 g.
10 Pcs. - blister packagings (6) - pob ntawv ntawm cardboard.
Pharmacological kev txiav txim
Qhov ncauj tshuaj hypoglycemic los ntawm cov pab pawg biguanide. Nws inhibits gluconeogenesis nyob rau hauv daim siab, txo qhov nqus ntawm cov piam thaj los ntawm txoj hnyuv, txhim kho kev siv ntawm cov kua nplaum ntev, thiab tseem ua rau kev nkag siab ntawm cov ntaub so ntswg mus rau insulin. Nws tsis cuam tshuam rau cov kua dej tso tawm los ntawm β-hlwb ntawm tus txiav, tsis ua rau kev mob hypoglycemic.
Lowers triglycerides thiab LDL.
Stabilizes lossis txo qhov hnyav lub cev.
Nws muaj cov nyhuv fibrinolytic vim yog kev tsuj tawm ntawm cov nqaij plasminogen activator inhibitor.
Cov Tshuaj Pharmacokinetics
Tom qab lub qhov ncauj tswj hwm, metformin yog nqus los ntawm cov hnyuv. Bioavailability tom qab noj cov qauv tshuaj yog 50-60%. Cmax tom qab kev tswj hwm ntawm qhov ncauj tau tiav tom qab 2.5 teev.
Nws xyaum tsis khi rau cov plasma protein. Nws accumulates nyob rau hauv salivary qog, nqaij, mob siab, thiab ob lub raum.
Nws tawm hauv cov zis tsis hloov pauv. T1 / 2 yog 1.5-4.5 teev.
Pharmacokinetics hauv cov chaw kuaj mob tshwj xeeb
Nrog kev ua haujlwm tsis zoo hauv lub raum, kom ceev cov tshuaj yog tau.
- Hom 2 mob ntshav qab zib mellitus nrog qhov tsis muaj txiaj ntsig ntawm kev kho kev noj haus (tshwj xeeb yog cov neeg mob rog rog).
Cov Yuav Tsum Muaj
- uas ketoacidosis, mob ntshav qab zib precoma, coma,
- Mob raum tsis zoo,
- cov xwm txheej uas tuaj yeem pab txhawb rau qhov mob lactic acidosis, suav nrog mob plawv thiab ua pa tsis ua haujlwm, mob theem myocardial infarction, mob cerebrovascular mob hnyav, lub cev qhuav dej, mob cawv mus ntev,
- Lub siab ua haujlwm tsis zoo,
- qaug cawv qaug cawv,
- muaj cov kab mob kis hnyav,
- lactic acidosis (suav nrog keeb kwm),
- Kev phais mob hnyav thiab raug mob (hauv cov teeb meem no, kev kho mob insulin yog qhia),
- siv tsis pub dhau 2 hnub ua ntej thiab 2 hnub tom qab ua kev tshawb fawb radioisotope lossis X-ray nrog kev qhia ntawm iodine-contrast contrast medium,
- kev ua raws nraim rau kev noj zaub mov kom tsis txhob muaj calories ntau tsawg (tsawg dua 1000 cal / hnub),
- lactation (pub niam mis),
- Hypersensitivity rau lub Cheebtsam ntawm cov tshuaj.
Nws tsis pom zoo kom siv cov tshuaj rau cov neeg mob hnub nyoog laus dua 60 xyoo uas ua haujlwm lub cev hnyav, vim tias qhov pheej hmoo ntawm mob lactic acidosis.
Teeb ntawm tus kheej, noj mus rau hauv tus account theem ntawm cov piam thaj hauv cov ntshav.
Qhov hno tshuaj thaum pib yog 500 mg 1-2 zaug / hnub lossis 850 mg 1 zaug / hnub. Tom qab, maj mam (1 zaug hauv ib lub lis piam), lub koob tshuaj tau nce mus rau 2-3 g / hnub. Qhov siab tshaj plaws niaj hnub noj yog 3 g.
Ntawm cov neeg laus laus koob tshuaj txhua hnub yuav tsum tsis pub ntau tshaj 1 g.
Vim tias muaj kev pheej hmoo ntxiv ntawm cov kab mob lactic acidosis, thaum muab tshuaj metformin rau cov neeg mob uas ua rau lub cev tsis txaus siab, qhov koob tshuaj yuav tsum raug txo kom tsawg.
Yuav tsum noj cov ntsiav tshuaj thaum noj mov lossis tom qab noj mov, tsis tas yuav zom thiab haus dej kom ntau.
Los ntawm lub plab zom mov: xeev siab, ntuav, "nws yog xim hlau" saj hauv lub qhov ncauj, tsis qab los noj mov, raws plab, pom pob, mob plab.
Los ntawm sab ntawm cov metabolism: tsis tshua muaj - lactic acidosis (yuav tsum muaj kev kho mob ncua ntev), nrog kev siv ntev - B12 hypovitaminosis (malabsorption).
Los ntawm cov kab ke hemopoietic: hauv qee kis - megaloblastic anemia.
Los ntawm cov kab ke endocrine: hypoglycemia (thaum siv hauv cov koob tshuaj tsis tsim nyog).
Kev tsis haum tshuaj: daim tawv nqaij ua pob.
Noj ntau dhau
Cov tsos mob tuag taus lactic acidosis yuav tsim. Qhov ua rau kev txhim kho ntawm cov kab mob lactic acid tuaj yeem tseem yog kev ruaj khov ntawm cov tshuaj vim tias lub zog ua haujlwm tsis zoo.
Cov tsos mob thaum ntxov ntawm lactic acidosis yog kev ua kom tsis muaj zog, xeev siab, ntuav, raws plab, txo qis lub cev kub, mob plab, mob leeg nqaij, txo ntshav siab, reflex bradyarrhythmia, yav tom ntej nws yuav ua rau muaj kev ua pa, kiv taub hau, tsis meej pem thiab tsis nco qab.
Kev Kho Mob: yog tias muaj cov cim ntawm cov kab mob lactic acidosis, kev kho mob nrog metformin yuav tsum nres tam sim ntawd, tus neeg mob mus pw hauv tsev kho mob sai sai thiab, tau txiav txim siab qhov concentration ntawm lactate, paub meej tias txoj kev kuaj mob. Hemodialysis siv tau zoo tshaj plaws rau kev tshem tawm lactate thiab metformin tawm hauv lub cev. Yog tias tsim nyog, nqa tawm cov kev kho mob.
Yeeb tshuaj sib cuam tshuam
Nrog rau kev siv tib lub sijhawm nrog sulfonylurea derivatives, acarbose, insulin, NSAIDs, MAO inhibitors, oxytetracycline, ACE inhibitors, clofibrate derivatives, cyclophosphamide thiab beta-blockers, nws yog qhov muaj peev xwm nce hypoglycemic effect ntawm metformin.
Nrog rau kev siv tib lub sijhawm nrog GCS, qhov ncauj tawm tsam, epinephrine (adrenaline), sympathomimetics, glucagon, cov thyroid hormones, thiazide thiab "voj" diuretics, phenothiazine derivatives thiab nicotinic acid, txo qis hauv cov nyhuv hypoglycemic ntawm metformin yog ua tau.
Cimetidine qeeb qeeb ntawm kev txiav tawm cov tshuaj metformin, vim tias qhov kev pheej hmoo ntawm lactic acidosis nce ntxiv.
Metformin tej zaum yuav ua rau cov tshuaj anticoagulants tsis muaj zog (coumarin derivatives).
Nrog rau kev tswj hwm ua ke nrog ethanol, txoj kev txhim kho ntawm cov kab mob lactic acidosis yog ua tau.
Nrog rau kev siv nifedipine tib lub sij hawm nce nqus ntawm metformin thiab Cmax, maj mam txo qis kev nthuav dav.
Cov tshuaj Cationic (amlodipine, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamteren, vancomycin) zais cia rau hauv cov menyuam ua lag luam sib tw rau tubular thauj tshuab thiab, nrog kev kho lub sijhawm ntev, tuaj yeem nce cov tshuaj Cmax los ntawm 60%.
Cov lus qhia tshwj xeeb
Thaum lub sijhawm siv cov tshuaj, cov ntsuas raum kev ua haujlwm yuav tsum raug saib xyuas. Tsawg kawg 2 zaug hauv ib xyoos, nrog rau qhov pom ntawm myalgia, lub lactate cov ntsiab lus hauv cov ntshav yuav tsum txiav txim siab.
Nws yog ib qho ua tau los siv Formetin txuam nrog sulfonylurea derivatives, thiab tshwj xeeb yog ua tib zoo saib xyuas ntshav qabzib ntau ntau yog tsim nyog.
Cuam tshuam rau kev muaj peev xwm tsav tsheb thiab tswj cov tshuab
Thaum siv los ua monotherapy, cov tshuaj tsis cuam tshuam rau lub peev xwm tsav tsheb thiab ua haujlwm nrog cov txheej txheem.
Nrog rau kev sib xyaw ntawm Formetin nrog lwm cov tshuaj hypoglycemic (sulfonylurea derivatives, insulin), kev mob ntshav qab zib tsis txaus siab tuaj yeem tsim nyob rau hauv uas muaj peev xwm tsav tsheb thiab lwm yam kev muaj feem phom sij uas xav tau kev nce siab thiab ceev ntawm psychomotor cov teeb meem kev mob ntau.
Tso cov ntaub ntawv thiab cov nyob ua ke
Muaj ib cov ntsiav tshuaj daim qauv ntawm cov tshuaj. Hauv pob ntawv cardboard tuaj yeem yog 30, 60 lossis 100 ntsiav tshuaj. Hauv daim ntawv ntawm kev ncua thiab lwm daim ntawv pharmacological, tus neeg sawv cev tsis tsim.
Cov tshuaj ua haujlwm nquag yog metformin hydrochloride ntau npaum li 500, 850 lossis 1000 mg. Cov ntsiab lus ntxiv ntawm cov tshuaj yog:
- croscarmellose sodium,
- magnesium stearate,
- polyvinylpyrrolidone.
Muaj ib cov ntsiav tshuaj daim qauv ntawm cov tshuaj. Hauv pob ntawv cardboard tuaj yeem yog 30, 60 lossis 100 ntsiav tshuaj. Hauv daim ntawv ntawm kev ncua thiab lwm daim ntawv pharmacological, tus neeg sawv cev tsis tsim.
Nws yog ib tus neeg sawv cev hypoglycemic tau tsim los ua tiav cov hom phiaj hauv qab no:
- txhim kho kev siv ntshav qabzib,
- Kev ua kom qeeb ntawm cov txheej txheem ntawm cov kua nplaum tsim muaj tshwm sim hauv lub siab,
- nce qhov rhiab siab ntawm cov nqaij ua rau muaj kev cuam tshuam ntawm cov tshuaj insulin (yog li, cov ntshav qab zib feem ntau tau mus txog),
- luj lub cev tsis sib xws
- txo cov theem ntawm qis lipoproteins thiab triglycerides,
- txo qhov kev nqus ntawm cov piam thaj nyob hauv txoj hnyuv.
Tsis tas li ntawd, cov tshuaj tsis cuam tshuam qhov zais cia cov tshuaj insulin hauv cov txiav thiab tsis ua rau cov tshuaj tiv thaiv hypoglycemic ntxiv.
Kev Noj Qab Haus Huv Nyob rau 120. Metformin. (03/20/2016)
Qab zib-txo cov ntsiav tshuaj Metformin
Yuav ua li cas siv FORMETINE
Cov tshuaj ntawm cov tshuaj yog xaiv ntawm tus kheej, noj mus rau hauv tus account ntsuas ntawm cov piam thaj hauv cov ntshav ntawm tus neeg mob. Pib nrog qhov ntau npaum li cas ntawm 500 mg 1-2 zaug hauv ib hnub lossis ib zaug siv 850 mg ntawm cov tshuaj.
Maj mam, cov koob tshuaj tau nce mus rau 2-3 g ib hnub. Qhov ntau npaum li cas ntawm cov tshuaj yuav tsum tsis pub ntau tshaj 3 g nyob rau ib hnub.
Cov tshuaj ntawm cov tshuaj yog xaiv ntawm tus kheej, noj mus rau hauv tus account ntsuas ntawm cov piam thaj hauv cov ntshav ntawm tus neeg mob.
Ua ntej lossis tom qab noj mov
Txais tos ntawm Formetin tuaj yeem nqa tau ob qho tib si tom qab noj mov, thiab thaum noj mov. Cov yeeb tshuaj tau tso cai haus nrog dej.
Nws raug nquahu kom siv tshuaj thaum yav tsaus ntuj, uas yuav zam kom tsis txhob muaj kev cuam tshuam dab tsi los ntawm kev mob plab. Thaum noj cov tshuaj 2 zaug hauv ib hnub, cov tshuaj yuav tsum noj thaum sawv ntxov thiab yav tsaus ntuj.
Lub plab zom mov
Nrog rau kev txhim kho kev mob tshwm sim cuam tshuam rau lub plab zom mov, tus neeg mob pib yws txog cov tsos mob hauv qab no:
- tsis qab los noj mov
- tsis xis nyob hauv plab
- xeev siab
- flatulence
- tsw phem hauv lub qhov ncauj
- zawv plab
- mob ncauj plab.
Ntuav thiab xeev ntuav yog ntawm cov kev phiv tshuaj los ntawm txoj hnyuv plab.
Hematopoietic plab hnyuv siab raum
Muaj qee zaus, cov tib neeg siv cov tshuaj tsim kho megaloblastic anemia. Hauv qhov no, kev ua txhaum yog pom los ntawm cov cim:
- kev xav ntawm txias
- chim quav
- kev zam rau nqaij,
- feem ntau tsis muaj zog
- paresthesias
- loog ntawm nqua
- txob taus.
Kev cuam tshuam nrog lwm yam tshuaj
Nws tsis pom zoo kom los sib xyaw ua ke siv cov formin thiab cov tshuaj hauv qab no.
- anticoagulants ntsig txog coumarin derivatives - cov tshuaj tsis muaj zog txaus,
- phenothiazine, diuretic tshuaj ntawm thiazide hom, glucagon, qhov ncauj txwv tsis pub muaj - qhov cuam tshuam ntawm cov tshuaj tiv thaiv nquag ntawm cov tshuaj txo qis,
- cimetidine - tshem tawm ntawm metformin los ntawm tus neeg mob lub cev,
- chlorpromazine - qhov kev pheej hmoo ntawm hyperglycemia nce,
- Danazole - cov nyhuv hyperglycemic yog kho kom zoo,
- ACE inhibitors thiab MAO, kev raug tsim ntawm clofibrate thiab NSAIDs - cov khoom ntawm Formetin nce.
Cawv tau zoo
Kev siv cov cawv uas muaj cawv haus ntau ntxiv ua rau muaj kev phom sij lactic acidosis.
Koj yuav tsum tsis txhob haus cawv kom tsis txhob muaj kev noj qab haus huv ntawm cov mob ua kua qaub.
Cov tshuaj tuaj yeem hloov nrog analogues.
Cov cuab yeej no yog:
- Glucophage - ib qho tshuaj los txo hyperglycemia.
- Siofor - ib qho yeeb tshuaj uas zwm rau pab pawg ntawm biguanides. Nws muaj cov txiaj ntsig zoo ntawm lipid metabolism thiab maj mam poob qis gluconeogenesis.
- Formin Long yog lub caij nyoog ntev ntawm cov tshuaj uas muaj 500, 750, 850 lossis 1000 mg ntawm cov tshuaj nquag.
- Gliformin yog ib hom tshuaj siv rau txo qis ntawm triglycerides thiab LDL. Cov tshuaj yuav tuaj yeem ua rau qeeb ntawm cov txheej txheem gluconeogenesis.
- Metformin - ib cov tshuaj nrog tib feem, tam sim no hauv qhov nyiaj ntawm 0.5 lossis 0.85 g.
- Bagomet yog ib qho tshuaj hypoglycemic npaj rau kev siv lub qhov ncauj.
Siofor thiab Glukofazh los ntawm ntshav qab zib thiab rau poob phaus
Mob ntshav qab zib, metformin, ntshav qab zib tsis pom kev | Dr. Tub Tua Neeg
Kev sim ua pov thawj ntawm cov kws kho mob thiab cov neeg mob txog Formetin
Arseny Vladimirov, endocrinologist, hnub nyoog 54 xyoos, Moscow
Kev siv FORMETINE yog kev cawm dim rau cov neeg mob uas kev rog dhau los vim yog mob ntshav qab zib. Cov cuab yeej ua rau qhov rhiab ntawm cov ntaub so ntswg mus rau insulin, tsis tas yuav ua kom muaj kev phom sij rau ntawm tus neeg mob. Lwm qhov kom zoo dua yog tus nqi pheej yig.
Valentina Korneva, tus kws kho keeb (endocrinologist), hnub nyoog 55 xyoos, Novosibirsk
Cov tshuaj yog qhov siv tau. Kuv muab tshuaj rau kuv cov neeg mob ntau zaus. Tsis muaj leej twg tsis txaus siab txog cov kev mob tshwm sim. Thiab tus mob yog normalizing.
Victoria, 45 xyoo, Volgograd
Nrog kev pab ntawm Formine, Kuv ua kom qhov hnyav tsis zoo, li vim muaj ntshav qab zib, nws tau pib nce mus rau hauv ntau. Cov tshuaj yog pheej yig, muaj nyob rau hauv Russia. Kuv noj cov tshuaj thaum yav tsaus ntuj. Txawm li cas los xij, koj yuav tsum ua raws li kev noj zaub mov, tsis suav lub tais thiab cov khoom uas muaj calories ntau.
Dmitry, 41 xyoo, Yekaterinburg
Kuv tau kho tshuaj formethine tau ntev, vim tias Kuv muaj ntshav qab zib tau ntau tshaj 15 xyoos. Cov tshuaj yeej pab, yam uas tsis muaj kev phiv. Kuv haus cov tshuaj 2 zaug ib hnub rau ib ntsiav tshuaj.
Maria, 56 xyoo, Saratov
Kuv tau raug tus mob ntshav qab zib tau thaj tsam li 5 lub xyoos. Txhua lub sijhawm no, Gliformin siv, uas yog ntawv sau los ntawm tus kws kho mob. Cov tshuaj tau pab, yog li kuv yuav siv nws txuas ntxiv, tab sis thaum mus ntsib tsev kho mob lawv tau hais tias tsis muaj ib yam tshuaj.
Cov tshuaj Formethine tau raug txiav txim siab ua qhov hloov. Kuv ntshai tias kev hloov pauv tshuaj tuaj yeem ua rau muaj qhov hloov pauv tsis zoo, tab sis nws ua tiav. Lub cev zam cov tshuaj no zoo, yog li kuv tseem siv ntxiv.
Tam sim no, ntau thiab ntau tus tib neeg tau muaj kev mob ntshav qab zib thiab rog dhau ntawm ntau hom nyuaj. Muaj ntau cov tshuaj los kho cov mob no. Ib qho ntawm lawv yog cov tshuaj "Formmetin". Txog nws cov xeeb ceem tshwj xeeb yuav raug sib tham hauv tsab xov xwm no.
Cov lus piav qhia ntawm cov sib xyaw thiab daim ntawv ntawm tso
Muaj ib ntsiav tshuaj:
nruab nrab molecular phaus povidone
Formetin muaj nyob hauv cov hlwv pob ntawm 100, 60 lossis 30 ntsiav tshuaj.
Cov xim ntawm cov ntsiav tshuaj yog dawb, thiab daim ntawv yog nyob ntawm qhov ntau npaum ntawm cov khoom tseem ceeb. Ntawm 500 mg, lawv muaj cov thooj voos kheej kheej sib npaug nrog cov nqis siab tshaj thiab cov chamfer. Tsis tas li, qhov ntau npaum ntawm 1000 mg thiab 850 mg yog "Formin". Cov ntsiav tshuaj hauv qhov no yog convex thiab oval. Lawv muaj kev pheej hmoo ib-sab.
Metformin ("Formethine") ua rau qeeb kawg gluconeogenesis uas tshwm sim hauv lub siab, thaum tseem muaj qis hauv nws cov khoom glycogen.
Cov cuab yeej no pab ua kom nyuaj ntxiv ntawm kev nqus ntawm cov piam thaj ntawm txoj hnyuv, txhim kho kev tshem tawm suab thaj los ntawm cov kab mob ncig.
Nyob rau tib lub sijhawm, cov ntaub so ntswg teb rau cov tshuaj insulin nce, tsis muaj kev cuam tshuam cov khoom lag luam ntawm nws cov endocrine los ntawm tus neeg mob hlwb los ntawm B hlwb, dhau ntawm cov tshuaj tiv thaiv hypoglycemic, txij li kev tsim cov tshuaj no tsis ua haujlwm.
Cov tshuaj "Formmetin", kev tshuaj xyuas uas hais txog nws cov txiaj ntsig, txo tus nqi "phem" roj thiab triglycerides hauv cov ntshav. cov lipoproteins ntau ntom tib lub sij hawm nce 20-30%.
Nrog rau qhov tsis muaj txiaj ntsig kev noj haus, cov tshuaj "Formmetin", cov lus qhia rau kev siv uas tau piav qhia hauv tsab xov xwm no, pab txo thiab / lossis tswj tus neeg mob lub cev qhov hnyav. Qhov no tshwm sim vim lub oxidation ntawm piam thaj nyob rau hauv ib txoj kev tsis muaj oxygen, nrog rau kev txo qis hauv qab.
Tsis tas li, txheej txheem ntawm plasminogen kev ua haujlwm ntawm cov nqaij mos tau npub los ntawm kev ua rau nws cov inhibitor, thiab muaj cov nyhuv hemostatic.
Lo lus uas peb
Cov tshuaj "Formin" yog siv los kho qee hom kabmob. Uas yog, nyob rau hauv muaj cov ntshav qab zib hom 2, nyob rau hauv cov teeb meem rog dhau los, thaum kev noj zaub mov tsis pab ua kom cov suab thaj theem tsis txaus, txawm tias ua ke nrog sulfonylurea. Kuj tseem muaj txiaj ntsig yog "Formin" rau kev poob phaus.
Yuav noj li cas?
Tus kws kho mob xaiv cov koob tshuaj ntawm cov tshuaj no raws li cov piam thaj hauv cov ntshav. Kev tswj hwm ntawm qhov ncauj yuav tsum tau nqa tawm tom qab noj mov, thaum haus kua ntau ntawm cov kua thiab tsis tas tua lub ntsiav tshuaj rau kev kho tshuab.
Raws li twb tau hais los saum no, kev noj tshuaj yog nyob ntawm cov piam thaj hauv cov ntshav. Nws pib nrog qhov tsawg kawg nkaus ntawm 0.5 g lossis 0.85 g ib hnub. Ob hnub tom qab pib kho nrog cov tshuaj no, cov ntsiab lus tsis tu ncua ntawm metformin hauv cov ntshav tau pom.
Yog tias tsim nyog, koj tuaj yeem maj mam nce qhov koob tshuaj kom muaj tus nqi siab. Nws yog sib npaug rau 3 grams.
Txij li thaum txoj kev loj hlob ntawm cov kab mob lactic acid feem ntau pom nyob rau hauv cov neeg laus, qhov siab tshaj plaws txhua hnub koob tshuaj yog 1 g rau lawv. Tsis tas li ntawd, ntau npaum li cas ntawm cov tshuaj raug txo rau hauv kev cuam tshuam ntawm metabolic cuam tshuam, kom tiv thaiv kev fab tshuaj, tshwm sim ua pob tawv nqaij, thiab lwm yam kev phiv uas yuav los tham hauv qab.
Sab sij huam
Qhov tshwm sim ntawm cov tsos mob tsis zoo no tshwm sim xws li "nws yog xim hlau" saj hauv lub qhov ncauj, ntuav, xeev siab, raws plab, roj, tsis qab los noj mov yuav tsum tau txiav kev siv tshuaj kho thiab hu rau tus kws kho mob tshwj xeeb.
Kev siv tshuaj ntev mus ntev ua rau muaj kev ua txhaum lossis ua tiav kev ua tiav ntawm kev nqus ntawm cov vitamin B12, uas ua rau kev sib txuam ntawm cov tom kawg hauv lub cev, ua rau hypovitaminosis. Hauv qee qhov tsis tshua muaj tshwm sim, qhov fab ntxeev tshwm sim - megaloblastic B12-tsis muaj zog txaus kom ntshav tsis txaus. Nrog rau cov koob tshuaj tsis yog, hypoglycemia yog ua tau. Ua xua rau daim tawv nqaij ua pob ua pob.
Yog li, cov tshuaj "Formin", kev tshuaj xyuas ntawm qhov uas pom zoo hauv kev siv, nws txawv, yuav tsum yog kws kho mob sau rau koj.
Cov txheej txheem tseem ceeb yog txiav txim siab los ntawm qhov peculiarity ntawm kev txuam nrog cov tshuaj "Formin" hauv lub cev thiab qhov tshwm sim ntawm qhov no.
Txhawm rau tiv thaiv kom tsis txhob tsub zuj zuj ntawm metformin thiab kev tiv thaiv ntawm cov kab mob lactic acidosis, nws yog qhov yuav tsum tau soj ntsuam cov ntsuas ntawm lub raum ua haujlwm thiab ntsuas kev tshuaj ntsuam xyuas seb puas muaj cov lactic acid hauv lub cev tsawg kawg 2 zaug hauv ib xyoos. Tsis tas li, nrog cov tsos ntawm qhov mob hauv cov leeg, yuav tsum kuaj xyuas zaum ob.
Cov nyhuv ntawm cov tshuaj no rau lub peev xwm tswj cov tshuab thiab tsav tsheb
Hauv qhov no, tseem muaj qee yam nuances. Cov txiaj ntsig ntawm "Formin" ntawm kev muaj peev xwm tswj cov txheej txheem thiab kev thauj mus los tsuas yog siv nws ua ke nrog cov tshuaj uas cuam tshuam rau cov txheej txheem ua haujlwm, xav tau cov lus teb sai thiab nce siab. Nov yog qhov tseem ceeb kom paub.
Siv rau kev pub niam mis thiab cev xeeb tub
Cov tshuaj "Formin", cov lus qhia rau kev siv uas tau piav qhia hauv cov ntawv sau no, muaj ib qeb kev nthuav tawm tus menyuam "B" raws li FDA. Thaum cev xeeb tub, cov tshuaj no tuaj yeem noj. Txawm li cas los xij, nws siv tau tsuas yog qee kis.
Uas yog, thaum xav pom tshwm sim los ntawm qhov kev kho mob no dhau qhov muaj kev pheej hmoo rau tus me nyuam hauv plab. Qee yam thiab kev kawm tshwj xeeb txog kev siv cov tshuaj xws li cov tshuaj "Formin" tsis tau ua thaum cev xeeb tub. Thaum lub sijhawm kho yuav tsum tsis pub niam mis rau menyuam noj.
Nyob rau hauv txhua rooj plaub, koj yuav tsum nrhiav tswv yim ntawm tus kws kho mob tsim nyog.
"Formin": analogues
Muaj ntau cov nyiaj ntau ntawm cov hom no. Cov qauv ntawm "Formin" yog npaj muaj nyob rau hauv lawv cov muaj pes tsawg leeg ua qhov tseem ceeb ntawm metformin hydrochloride.
Ib qho piv txwv yog cov tshuaj ntawm Lavxias cov tuam txhab: Vero-Metformin, Gliformin, Metformin, Metformin Richter, thiab txawv teb chaws - Glyukofag, Glyukofazh thiab Glyukofazh Ntev (Fabkis), Langerin "(Slovakia)," Metfogamma "nrog ntau qhov sib txawv ntawm cov tshuaj nquag 0.100, 0.500 thiab 0.850 g (Lub teb chaws Yelemees).
Tus nqi nruab nrab ntawm cov tshuaj "Formmetin" yog tsim raws li cov ntau npaum: ntawm 59 rubles. rau sawv hlwv 0.5 g, 133 rubles. rau 0.85 g thiab 232 rubles. rau 1 g.
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Mob ntshav qab zib Hom 2
Kev phom sij thiab lub txim ntawm ntshav qab zib Insulin-hom mob ntshav qab zib hom 1 yog ib tug mob ntev los ntawm cov insulin tsis txaus tsim los ntawm lub hlwb pancreatic. ... -
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