Cov lus qhia rau kev siv tshuaj Bayeta > Kev khomob thiab kev tiv thaiv

Kev daws rau kev tswj hwm subcutaneous - 1 ml:

cov tshuaj nquag: exenatide - 250 mcg,
kev tshem tawm: sodium acetate trihydrate, glacial acetic acid, mannitol, metacresol, dej d / i.

Hauv daim ntawv xaum npaws nrog daim cartridges ntawm 1.2 lossis 2.4 ml, hauv ib pob ntawv los ntawm daim ntawv 1 lub npias.

Kev daws rau sc tswj hwm yog tsis muaj xim, pob tshab.

Xuas. Tom qab sc tswj fwm exenatide hauv ib koob ntawm 10 μg rau cov neeg mob uas muaj ntshav qab zib hom 2 mellitus, exenatide nrawm nrawm thiab tom qab 2.1 teev txog Cmax, uas yog 211 pg / ml. AUCo-inf yog 1036 pg × h / ml. Thaum tso tawm rau exenatide, AUC nce rau hauv kev faib ua feem rau cov koob tshuaj nce ntxiv ntawm 5 txog 10 μg, thaum tsis muaj qhov sib luag ntau ntawm Cmax. Tib cov txiaj ntsig tau pom nrog kev coj ua subcutaneous ntawm exenatide hauv plab, ncej puab lossis caj npab.

Kev xa Khoom. Qhov pom meej ntim ntawm kev faib tawm (Vd) ntawm exenatide tom qab sc tswj hwm yog 28.3 litres.

Kev ntsuas phoo thiab nthuav tawm. Exenatide yog feem ntau raug ntog los ntawm glomerular pom ua raws los ntawm kev kho mob proteolytic kev ua haujlwm. Exenatide tshem tawm yog 9.1 l / h. Qhov kawg T1 / 2 yog 2.4 teev. Cov tshuaj uas txawv ntawm exenatide yog koob tshuaj ywj siab. Ntsuas qhov ntau ntawm exenatide raug txiav txim kwv yees li 10 teev tom qab noj tshuaj.

Pharmacokinetics hauv cov chaw kuaj mob tshwj xeeb. Hauv cov neeg mob uas muaj mob me me los yog mob raum (Cl creatinine 30-80 ml / min), kev tshem tawm ntawm exenatide tsis txawv qhov kev pom ntawm cov neeg mob uas muaj lub raum tsis ua haujlwm, yog li ntawd, kev kho tshuaj tsis tas yuav tsum tau ua. Txawm li cas los xij, hauv cov neeg mob uas mob raum ua rau lub raum tsis ua haujlwm, kev txiav txim siab nruab nrab yog txo mus rau 0.9 l / h (piv rau 9.1 l / teev hauv cov ntsiab lus noj qab haus huv).

Txij li thaum exenatide feem ntau yog ua rau lub raum, nws ntseeg tau tias kev ua haujlwm hauv daim siab ua haujlwm tsis hloov pauv qhov tshwj xeeb ntawm exenatide hauv cov ntshav.

Lub hnub nyoog tsis cuam tshuam rau pharmacokinetic cov yam ntxwv ntawm exenatide. Yog li, cov neeg laus laus tsis tas yuav tsum ua qhov hloov kho koob tshuaj.

Cov pharmacokinetics ntawm exenatide hauv cov menyuam yaus tsis tau kawm.

Tsis muaj qhov sib txawv ntau qhov sib txawv ntawm tus txiv neej thiab poj niam hauv pharmacokinetics ntawm exenatide.

Cov chaw muag tshuaj ntawm exenatide hauv cov neeg sawv cev ntawm ntau haiv neeg sib txawv tsis hloov. Tsis tas yuav muab hloov kho los ntawm haiv neeg keeb kwm.

Tsis muaj qhov tshwm sim pom tseeb ntawm kev ntsuas lub cev (BMI) thiab exenatide pharmacokinetics. Koob tshuaj hloov kho raws li BMI yog tsis xav tau.

Exenatide (Exendin-4) yog qhov ua kom zoo ntxiv thiab yog 39-amino acid amidopeptide. Cov ntau zuj zus, xws li cov glucagon-zoo li peptide-1 (GLP-1), txhim kho cov kua dej tsis txaus rau cov kua dej, txhim kho beta ntawm tes ua haujlwm, txwv tsis pub muaj ntshav qabzib ntau thiab ua rau lub plab zom mov tom qab lawv nkag mus rau hauv cov ntshav tawm ntawm txoj hnyuv. Exenatide yog lub zog loj zuj zus uas ua rau cov ntshav qabzib-insulin muaj peev xwm ua rau muaj cov ntshav qabzib ntau yam thiab muaj lwm yam teebmeem ntshav qabzib ntau ntxiv rau cov neeg mob ntshav qab zib hom 2.

Cov amino acid sib lawv liag ntawm exenatide ib nrab sib raug rau ntu ntawm tib neeg GLP-1, los ntawm qhov uas nws khi thiab ua rau GLP-1 cov neeg txais kev pabcuam hauv tib neeg, uas ua rau muaj kev sib txuas ntxiv rau cov piam thaj thiab kev tso ntshav ntawm insulin los ntawm pancreatic beta hlwb nrog kev koom tes ntawm cyclic adenosine monophosphate (AMP) thiab / lossis lwm txoj kev taw qhia kev rau sab kev kawm. Exenatide txhawb kev tso tawm ntawm insulin los ntawm beta hlwb nyob ib puag ncig ntawm kev nce siab nyob hauv siab.

Exenatide sib txawv hauv cov qauv tshuaj thiab cov tshuaj pharmacological los ntawm insulin, sulfonylurea derivatives, D-phenylalanine derivatives thiab meglitinides, biguanides, thiazolidinediones thiab alpha-glucosidase inhibitors.

Exenatide txhim kho glycemic tswj nyob rau hauv cov neeg mob uas muaj ntshav qab zib hom 2 vim yog cov tshuab hauv qab no.

Hauv hyperglycemic tej yam kev mob, exenatide ua rau cov piam thaj tsis muaj peev xwm tso cov kua dej ntawm cov kua dej los ntawm pancreatic beta hlwb. Qhov insulin secretion tso tseg thaum cov concentration ntawm cov piam thaj hauv cov ntshav txo qis thiab nws nce mus rau qhov qub, yog li txo cov kev pheej hmoo ntawm cov ntshav qog ntshav qab zib.

Cov tshuaj insulin tso tawm thaum thawj 10 feeb, hu ua "thawj theem ntawm cov tshuaj insulin", tshwj xeeb tshaj yog qhaj ntawv ntawm cov neeg mob ntshav qab zib hom 2. Tsis tas li ntawd, qhov poob ntawm thawj theem ntawm cov tshuaj insulin yog ib qho kev ua tsis tiav ntawm beta cell ua haujlwm hauv ntshav qab zib hom 2. rov qab los yog ua kom zoo ntxiv rau theem ob thiab theem ob ntawm kev muaj tshuaj insulin hauv cov neeg mob uas muaj ntshav qab zib hom 2.

Hauv cov neeg mob uas muaj hom 2 mob ntshav qab zib mellitus tawm tsam keeb kwm ntawm hyperglycemia, kev coj noj coj ua ntawm exenatide txwv kev tso cia ntau dhau ntawm glucagon. Txawm li cas los xij, exenatide tsis cuam tshuam rau lub cev glucagon teb li cas rau kev mob ntshav qab zib.

Nws tau pom tias kev coj noj coj ua ntawm exenatide ua rau kev poob qis thiab ua kom tsawg dua ntawm txoj kev noj zaub mov, inhibits lub cev muaj zog ntawm lub plab, uas ua rau lub qeeb ntawm nws qhov khoob.

Hauv cov neeg mob uas muaj hom 2 mob ntshav qab zib mellitus, kev kho mob exenatide nrog kev sib xyaw nrog metformin thiab / lossis sulfonylurea kev npaj ua rau txo qis ntshav qabzib, ntshav qabzib tom qab, thiab glycosylated hemoglobin index (HbA1c), thiaj li txhim kho glycemic tswj hauv cov neeg mob no.

Cov Tshuaj Hauv Tshuaj

Exenatide txhim kho glycemic tswj nyob rau hauv cov neeg mob uas muaj ntshav qab zib hom 2 vim yog cov tshuab hauv qab no.

Cov Tshuaj Pharmacokinetics

Xuas. Tom qab s / c tswj hwm ntawm exenatide ntawm ib koob ntawm 10 μg rau cov neeg mob uas muaj ntshav qab zib hom 2 mellitus, exenatide yog nqus sai thiab tom qab 2.1 teev nce mus txog C_max uas yog 211 pg / ml. Auc_o-inf yog 1036 pg × h / ml. Thaum tso tawm rau exenatide, AUC nce rau hauv kev faib ua feem rau cov koob tshuaj nce ntxiv ntawm 5 txog 10 μg, thaum uas tsis muaj qhov sib npaug ntawm C_maxCov. Tib cov txiaj ntsig tau pom nrog kev coj ua subcutaneous ntawm exenatide hauv plab, ncej puab lossis caj npab.

Kev xa Khoom. Cov pom tseeb ntawm kev faib tawm (V_d ) exenatide tom qab kev tswj hwm sc yog 28.3 litres.

Kev ntsuas phoo thiab nthuav tawm. Exenatide yog feem ntau raug ntog los ntawm glomerular pom ua raws los ntawm kev kho mob proteolytic kev ua haujlwm. Exenatide tshem tawm yog 9.1 l / h. Kawg T_1/2 yog 2,4 teev. Cov tshuaj sib txawv ntawm cov exenatide no yog qhov tshuaj noj kheej. Ntsuas qhov ntau ntawm exenatide raug txiav txim kwv yees li 10 teev tom qab noj tshuaj.

Pharmacokinetics hauv cov chaw kuaj mob tshwj xeeb. Hauv cov neeg mob uas muaj mob me me los yog mob raum (Cl creatinine 30-80 ml / min), kev tshem tawm ntawm exenatide tsis txawv qhov kev pom ntawm cov neeg mob uas muaj lub raum tsis ua haujlwm, yog li ntawd, kev kho tshuaj tsis tas yuav tsum tau ua. Txawm li cas los xij, hauv cov neeg mob uas mob raum ua rau lub raum tsis ua haujlwm, kev txiav txim siab nruab nrab yog txo mus rau 0.9 l / h (piv rau 9.1 l / teev hauv cov ntsiab lus noj qab haus huv).

Txij li thaum exenatide feem ntau yog ua rau lub raum, nws ntseeg tau tias kev ua haujlwm hauv daim siab ua haujlwm tsis hloov pauv qhov tshwj xeeb ntawm exenatide hauv cov ntshav.

Lub hnub nyoog tsis cuam tshuam rau pharmacokinetic cov yam ntxwv ntawm exenatide. Yog li, cov neeg laus laus tsis tas yuav tsum ua qhov hloov kho koob tshuaj.

Cov pharmacokinetics ntawm exenatide hauv cov menyuam yaus tsis tau kawm.

Tsis muaj qhov sib txawv ntau qhov sib txawv ntawm tus txiv neej thiab poj niam hauv pharmacokinetics ntawm exenatide.

Cov chaw muag tshuaj ntawm exenatide hauv cov neeg sawv cev ntawm ntau haiv neeg sib txawv tsis hloov. Tsis tas yuav muab hloov kho los ntawm haiv neeg keeb kwm.

Tsis muaj qhov tshwm sim pom tseeb ntawm kev ntsuas lub cev (BMI) thiab exenatide pharmacokinetics. Koob tshuaj hloov kho raws li BMI yog tsis xav tau.

Cov Yuav Tsum Muaj

muaj lub cev tsis haum rau lub tshuaj,

yam 1 mob ntshav qab zib mellitus lossis qhov muaj ntshav qab zib ketoacidosis,

mob raum tsis ua haujlwm (Cl creatinine - lub plab zom mov nrog cov hlab ntsws ua kom haum,

lactation (noj niam mis),

cov menyuam yaus hnub nyoog qis dua 18 xyoo (kev nyab xeeb thiab kev ua tau zoo ntawm cov tshuaj hauv cov menyuam yaus tseem tsis tau tsim).

Sab sij huam

Cov kev tsis zoo uas tshwm sim ntau tshaj li ntawm qhov teeb meem raug mob cais tawm tau teev raws li cov ntawv pov thawj hauv qab: feem ntau - ≥10%, feem ntau - ≥1%, tab sis lub hauv nruab nrab ntawm cov hlab ntsha: feem ntau - kiv taub hau, mob taub hau, tsis tshua-tsaug zog.

Los ntawm cov kab ke endocrine: heev feem ntau - hypoglycemia (ua ke nrog sulfonylurea derivatives), feem ntau - zoo nkaus li tshee tshee, tsis muaj zog, hyperhidrosis.

Kev tsis haum tshuaj: tsis tshua muaj - muaj pob liab vog, khaus, angioedema, tsis tshua muaj - kev tiv thaiv anaphylactic.

Lwm yam: feem ntau - kev tawm tsam ntawm daim tawv nqaij ntawm qhov chaw txhaj tshuaj, tsis tshua muaj - lub cev qhuav dej (cuam tshuam nrog xeev siab, ntuav thiab / lossis zawv plab). Ntau qhov xwm txheej ntawm cov ntshav coagulation sijhawm (INR) tau tshaj tawm nrog kev siv tib lub sij hawm ntawm warfarin thiab exenatide, uas qee zaum nrog los ntshav.

Vim yog qhov tseeb tias qhov zaus ntawm hypoglycemia nce nrog kev sib koom tes tswj hwm ntawm Baeta ® kev npaj nrog sulfonylurea derivatives, nws yog qhov yuav tsum tau muab rau txo qis ntawm cov tshuaj sulfonylurea derivatives nrog kev pheej hmoo ntawm hypoglycemia. Feem ntau qhov tshwm sim ntawm cov ntshav qog nqaij hlav hauv qhov sib luag tau mob me me los yog mob nyhav thiab raug tso tseg los ntawm kev noj zaub mov hauv qhov ncauj.

Feem ntau, cov kev mob tshwm sim tau mob sib khuav me me los sis mob hnyav thiab tsis ua rau txo kev kho mob. Feem ntau, tau sau npe ntawm xeev siab txog qhov mob sib khuav xwb los yog siv yoog tau siv tshuaj ntau thiab tsawg zuj zus, tsis muaj cuam tshuam nrog kev ua si txhua hnub.

Kev sib txuam

Bayeta ® yuav tsum siv nrog ceev faj hauv cov neeg mob noj tshuaj ntawm qhov ncauj uas yuav tsum nqus sai los ntawm kev mob plab, vim tias Baeta ® yuav ncua kev mob plab zom mov. Cov neeg mob yuav tsum raug qhia kom noj cov tshuaj hauv qhov ncauj, cov nyhuv ntawm nws nyob ntawm lawv lub luag haujlwm tseem ceeb (piv txwv li tshuaj tua kab mob), tsawg kawg 1 teev ua ntej kev tswj hwm ntawm exenatide. Yog tias cov tshuaj no yuav tsum tau noj nrog zaub mov, tom qab ntawd lawv yuav tsum noj thaum cov zaub mov noj thaum cov tshuaj exenatide tsis tau txais.

Nrog kev tswj hwm tib lub sij hawm ntawm digoxin (ntawm koob tshuaj 0.25 mg 1 zaug / hnub) nrog Bayeta ®, C txo_max digoxin los ntawm 17%, thiab T_max nce li ntawm 2.5 teev. Txawm li cas los xij, tag nrho cov txiaj ntsig pharmacokinetic ntawm qhov tsis sib txig tsis hloov.

Tawm tsam keeb kwm ntawm cov lus qhia ntawm cov tshuaj Bayeta ® AUC thiab C_max lovastatin poob los ntawm kwv yees li 40 thiab 28%, thiab T_max nce ntxiv li ntawm 4 teev .Txoj kev tswj hwm ntawm Bayeta ® nrog HMG-CoA reductase inhibitors tsis nrog kev hloov pauv hauv cov ntshav lipid (HDL cholesterol, LDL cholesterol, tag nrho cov roj cholesterol thiab triglycerides).

Hauv cov neeg mob uas mob ntshav me los sis mob ntshav qis los ntawm lisinopril (5-20 mg / hnub), Bayeta ® tsis hloov AUC thiab C_max lisinopril ntawm kev sib npaug. T_max lisinopril ntawm qhov sib npaug nce los ntawm 2 teev Tsis tau muaj qhov hloov pauv ntawm qhov ntsuas ntawm nruab nrab txhua hnub SBP thiab DBP.

Nws tau sau tseg tias nrog kev qhia ntawm warfarin 30 feeb tom qab kev npaj Bayeta. T_max tau nce li thaj tsam li 2 teev_max thiab AUC tsis tau pom.

Kev siv Bayeta ® nrog cov tshuaj insulin, D-phenylalanine derivatives, meglitinides lossis alpha-glucosidase inhibitors tsis tau kawm.

Tsuas tshuaj thiab tswj hwm

S / c rau tus ncej puab, plab, lossis caj npab.

Thawj koob tshuaj yog 5 mcg, uas tau txhaj tshuaj 2 zaug / hnub thaum txhua lub sijhawm 60-feeb ua ntej noj thaum sawv ntxov thiab yav tsaus ntuj noj mov. Tsis txhob noj cov tshuaj tom qab noj mov. Yog tias kev txhaj tshuaj tsis tiav, kev kho mob mus txuas ntxiv yam tsis hloov pauv koob tshuaj.

1 lub hlis tom qab pib txoj kev kho mob, cov koob tshuaj yuav raug nce ntxiv rau 10 mcg 2 zaug / hnub.

Thaum ua ke nrog metformin, thiazolidinedione, lossis nrog kev sib xyaw ntawm cov tshuaj no, cov koob tshuaj thawj zaug ntawm metformin thiab / lossis thiazolidinedione tsis tuaj yeem hloov pauv. Thaum muaj kev sib xyaw ntawm Bayeta ® nrog sulfonylurea derivatives, yuav tsum tau txo koob tshuaj sulfonylurea derivative kom txo qis kev pheej hmoo ntawm hypoglycemia.

Cov lus qhia tshwj xeeb

Nws tsis pom zoo hauv / hauv lossis hauv / m tswj hwm ntawm cov tshuaj.

Bayeta ® yuav tsum tsis txhob siv yog tias pom muaj nyob hauv qhov kev daws teeb meem lossis yog hais tias daws tau pos huab lossis muaj xim.

Tshuaj tua kab mob rau exenatide tuaj yeem tshwm sim thaum kev kho mob nrog Bayeta ®. Txawm li cas los xij, qhov no tsis cuam tshuam qhov nquag thiab hom ntawm cov kev mob tshwm sim.

Cov neeg mob yuav tsum paub tias kev kho mob nrog Bayeta ® tuaj yeem ua rau tsis qab los noj mov thiab / lossis lub cev qhov hnyav thiab tias vim muaj cov teebmeem no tsis tas yuav hloov pauv kev noj tshuaj.

Cov neeg mob ua ntej pib kho nrog Bayeta ® yuav tsum paub lawv tus kheej nrog Phau Ntawv Qhia kom siv cov koob txhaj tshuaj khi nrog cov tshuaj.

Cov txiaj ntsig ntawm kev sim tshuaj

Hauv kev tshawb fawb preclinical hauv cov nas thiab nas, tsis muaj cov teebmeem carcinogenic ntawm exenatide pom. Thaum cov nas tau muab koob tshuaj 128 zaug rau hauv tib neeg, ntau qhov nce hauv C-cell cov thyroid adenomas tau sau tseg tsis muaj cov cim tsis zoo, uas cuam tshuam nrog kev nce hauv lub neej ntawm kev sim cov tsiaj uas tau txais exenatide.

Kev faib tawm hauv lub cev-Kho-tshuaj lom neeg muaj tshuaj (ATX)

Anatomical-tshuaj-kev faib tawm tshuaj lom neeg (anatomical-kho-tshuaj lom neeg, ATX) - Thoob ntiaj teb kev faib tawm cov tshuaj yeeb tshuaj. Lub hom phiaj tseem ceeb ntawm ATX yog txhawm rau muab kev txheeb cais ntawm kev noj tshuaj.

Raws li ATX, Tshuaj Bayeta yog nyob rau ntu "Lwm cov tshuaj rau kev kho mob ntshav qab zib mellitus".

Nosological kev faib tawm (ICD-10)

Thoob ntiaj teb kev faib cov kab mob ntawm Kaum Kho (ICD-10) yog cov qauv ntsuas kev ntsuas hauv kev saib xyuas kev noj qab haus huv, tshuaj, kev kis mob, nrog rau kev txheeb xyuas cov xwm txheej kev noj qab haus huv ntawm cov pej xeem. Raws li ICD-10, Bayeta (Exenatide), cov tshuaj yuav siv tau rau cov kabmob no:

E11 Tsis mob ntshav qab zib tsis yog insulin-hom mob ntshav qab zib (hom 2 mob ntshav qab zib mellitus).

Nquag muaj Baeta

Sab nrauv - nce zuj zus, qhov khoom sib txuas ua ke tau tshwm sim los ntawm kev sib koom tes ntawm Amylin Pharmaceuticals thiab Eli Lilly thiab Co. Exenatide yog muab rho tawm los ntawm cov qaub ncaug ntawm Gila dab nab qa dev (Hila nab-qa), uas nyob hauv Arizona, Asmeskas. Nyob rau hauv ib lub sijhawm, cov kws kho tsiaj txhu tau saib xyuas zoo - Khila lizards tuaj yeem siv sijhawm ntev (txog li plaub hlis) ua yam tsis muaj zaub mov. Tom qab ntawd, cov kws tshawb fawb tau kawm txog qhov tshwm sim no pom tau tias txiav ntawm txiav ntawm cov tsiaj reptiles thaum lub sijhawm "yoo mov" thiab tsis ua haujlwm. Exendin-4 (Exenatide), nyob rau ntawm lub hauv paus uas cov kev npaj Bayeta tau tsim, pab cov lizards zom cov zaub mov.

Daim Ntawv Suav Ntxiv Cov Khoom Siv: C184 H282 N50 O60S.

Lwm cov ntsiab lus nthuav dav txog cov tshuaj tuaj yeem pom nyob hauv ntu qhov chaw ntawm lub portal.

Daim ntawv tso tawm thiab ntau npaum Baeta

Baeta yog muaj nyob rau hauv daim ntawv ntawm rab koob txhaj tshuaj hauv ob qhov tshuaj:

ib qho kev daws teeb meem rau kev tswj hwm ntawm subcutaneous ntawm 250 μg / ml, lub taub ntim ntawm 1.2 ml hauv rab koob tshuaj (5 μg),
ib qho kev daws teeb meem rau kev tswj hwm ntawm subcutaneous ntawm 250 μg / ml, daim cartridge ntawm 2.4 ml hauv rab koob tshuaj (10 μg).

Kev siv tshuaj rau feem ntau hauv Bayeta cov khw muag tshuaj yog 1.2 ml (5 mcg).

Baeta ntim suav nrog:

Nyem thiab qhia cov lus nrog koj cov phooj ywg:

rab koob xaum nrog kev daws teeb meem rau kev coj ntawm subcutaneous,
cov lus qhia rau kev siv kho mob,
cwj mem kua muag phau ntawv
ib pob ntawm cardboard.

Kev taw qhia Bayeta

Bayeta yog qhia rau kev siv hauv cov xwm txheej hauv qab no:

Hom 2 mob ntshav qab zib mellitus raws li kev kho mob monotherapy ntxiv rau kev tawm dag zog lub cev thiab kev noj haus kom ua tiav glycemic tswj,
Hom 2 mob ntshav qab zib mellitus raws li kev kho mob rau cov tshuaj sulfonylurea derivative, metformin, thiazolidinedione, kev sib xyaw ntawm metformin thiab sulfonylurea derivative, los yog metformin thiab thiazolidinedione tsis muaj kev tswj zoo glycemic.

Phiv Rov Los Ntawm Baeta

Los ntawm kev siv Baeta yuav Cov kev mob tshwm sim hauv qab no:

Los ntawm lub plab zom mov:

xeev siab
ntuav
zawv plab
tsis qab los
gastroesophageal reflux,
dyspepsia
tsam plab
mob plab
cem quav
nplawm
flatulence
ua txhaum ntawm saj.

Los ntawm lub hauv nruab nrab hauv lub paj hlwb:

kiv taub hau
mob taub hau
tsaug zog

Los ntawm cov kab ke endocrine:

zoo nkaus li kev tshee hnyo
ntshav qab zib,
hyperhidrosis
tsis muaj zog.

angioedema,
ua pob
khaus
anaphylactic cov tshuaj tiv thaiv.

Lwm cov kev phiv:

khaus, liab, tawm pob ntawm thaj chaw txhaj tshuaj,
lub cev qhuav dej.

Noj ntau dua Byetoy

Yog tias dhau ntawm kev noj tshuaj ntau dhau ntawm Bayeta (koob tshuaj 10 zaug qhov ntau tshaj qhov pom zoo tshaj plaws), cov tsos mob hauv qab no raug pom:

ntuav
xeev siab
kev txhim kho ntshav sai ntawm hypoglycemia.

Kev kho mob nrog ib qho kev noj qab haus huv ntawm Bayeta suav nrog kev kho mob, nrog rau kev tswj hwm ntawm cov ntshav qabzib nrog cov ntshav qabzib heev.

Cov lus qhia rau kev siv byeta

Nyeem cov lus qhia no rau kev siv byet tsis ua rau tus neeg mob siab rau txoj kev kawm ntawm "Cov lus qhia rau kev siv tshuaj kho mob "nyob hauv lub thawv ntawv thawv nrog ib tus cwj mem syringe Baeta. Cov lus qhia no siv rau kev siv cov tshuaj tov rau kev tswj hwm ntawm 250 μg / ml, hauv daim cartridge ntawm 1, 2 ml hauv ib rab koob (5 μg).

Kom tau txais txiaj ntsig zoo tshaj plaws los ntawm kev siv Bayeta, cov koob txhaj tshuaj yuav tsum siv kom raug. Ua tsis tiav cov lus qhia siv rau Bayeta koob txhaj tshuaj tuaj yeem ua rau qhov kev qhia ntawm koob tshuaj tsis haum, tawg ntawm daim phwj syringe, thiab kis tau tus mob. Cov lus qhia rau kev siv tsis hloov kev sab laj nrog koj tus kws kho mob hais txog kev mob lossis kev kho mob. Yog tias muaj qhov nyuaj ntawm kev siv Bayeta koob txhaj tshuaj, koj yuav tsum sab laj nrog koj tus kws kho mob. Lub taub hau koob txhaj tshuaj muaj cov tshuaj txaus rau siv hauv 30 hnub. Lub tshuab nqus raj ua yeeb yam ua qhov kev ywj pheej ntawm cov khoom.

Nws tsis tuaj yeem lees hloov cov tshuaj los ntawm phwj daj mus rau hauv cov tes phwj.

Yog tias ib qho twg ntawm xaum xaum tawg lossis tawg, tsis txhob siv cov xaum xias.

Nws tsis raug nquahu kom siv cov kua xaum xaum rau cov neeg muaj qhov muag tsis pom kev lossis muaj lub zeem muag tsis muaj txiaj ntsig yam tsis muaj kev pab ntawm cov neeg pom. Hauv qhov xwm txheej no, kev pab ntawm ib tus neeg kawm tiav los siv kev xaum xim yuav tsum tau ua.

Cov kws kho mob lossis cov neeg kho mob yuav tsum ua raws li cov cai tsim los tuav koob.

Thaum siv Bayeta koob txhaj tshuaj, koj yuav tsum ua raws li cov lus qhia txog kev txhaj tshuaj kom huv si uas koj tus kws kho mob pom zoo.

Raws li cov lus qhia, Tshuaj Bayeta yog siv los ua ib qho kev txhaj tshuaj rau hauv cov rog subcutaneous hauv plab, ncej lossis caj npab.

Thaum lub sijhawm pib siv, cov tshuaj tau sau tseg rau kev siv ntawm 5 mcg ob zaug hauv ib hnub (thaum sawv ntxov thiab yav tsaus ntuj teev) rau ib teev lossis hauv ib teev ua ntej noj mov. Thaum muaj kev ua txhaum ntawm kev tswj hwm ntawm Bayeta, kev noj ntau ntau tsis hloov. 30 hnub tom qab pib noj cov tshuaj txhaj ntxiv nce mus rau 10 mcg (ob zaug hauv ib hnub).

Cov tshuaj yuav tsum tsis txhob siv tshuaj tom qab noj mov. Nws tsis pom zoo kom tswj hwm tshuaj rau hauv txoj hnyuv los yog intramuscularly. Yog hais tias qhov txawv txawv txawv pom tau hauv qhov kev daws teeb meem, lossis yog tias kev daws nws tus kheej yog huab lossis muaj xim, qhov kev npaj Bayeta yuav tsum tsis txhob siv.

Hauv cov lus qhia rau kev siv, koj yuav tsum tawm ib daim ntawv khaws tseg ntawm qhov tseeb thiab hnub tim thawj siv tus cwj mem xwj.

Kev siv cov tshuaj Bayeta koob txhaj tshuaj yog nqa tawm tsis pub dhau 30 hnub tom qab siv thawj zaug, muab cov txheej txheem rau kev npaj cov kua xaum xim tshiab nqa tawm. 30 hnub tom qab siv thawj zaug, Baeta syringe cwj mem yuav tsum tau muab pov tseg, txawm tias nws tsis khoob kiag li.

Tus cwj mem Baeta koob txhaj tshuaj yuav tsum tsis txhob siv tom qab hnub tas sij hawm qhia ntawm qhov chaw tsim khoom ntim.

Yog tias tsim nyog, so daim ntaub qhwv lub qhov muag tawm ntawm sab nraud nrog daim ntaub dawb huv.

Thaum siv daim duab syringe cwj mem, cov tshuaj dawb yuav tshwm sim rau ntawm qhov taub ntawm lub taub hau, uas yuav tsum tau
tshem tawm nrog ib daim ntaub lossis paj rwb swab moistened nrog cawv.

Nrog kev sib xyaw ntawm Bayet nrog metformin, thiazolidinedione, lossis nrog kev sib xyaw ntawm cov tshuaj no, cov koob tshuaj thawj zaug ntawm metformin thiab / lossis thiazolidinedione tsis tuaj yeem hloov pauv.

Kev sib xyaw ntawm Baeta nrog sulfonylurea derivatives tuaj yeem xav kom txo qis ntawm cov tshuaj sulfonylurea derivative txhawm rau txo qis kev pheej hmoo ntawm kev mob ntshav qab zib.

Ua ntej pib kho mob nrog Baeta, tus neeg mob yuav tsum nyeem cov lus qhia txuas nrog "Lus qhia rau kev siv kua xaum xim".

Baeta yuav tsum ceeb toom rau cov neeg mob noj tshuaj uas yuav tsum tau nqus sai ntawm txoj hnyuv - Baeta ua rau lub plab zom mov qeeb. Cov neeg mob yuav tsum raug qhia kom noj cov tshuaj noj ntawm qhov ncauj, cov nyhuv ntawm uas nyob ntawm lawv lub luag haujlwm kev tswj hwm (tshuaj tua kab mob), tsawg kawg ib teev ua ntej kev tswj hwm ntawm Bayet. Yog tias cov tshuaj no ua ke nrog cov zaub mov, lawv yuav tsum tau noj thaum cov zaub mov noj thaum Baeta tsis siv.

Thaum sau tshuaj rau Baeta ua ke nrog digoxin (ntawm koob tshuaj 0.25 mg ib hnub ib zaug), Cmax ntawm digoxin txo qis li 17%, Tmax nce ntxiv los ntawm ob thiab ib nrab teev. Hauv qhov no, qhov kev txiav txim siab tag nrho ntawm pharmacokinetic ntawm equilibrium tsis hloov. Tawm tsam keeb kwm yav dhau los ntawm kev nthuav qhia ntawm Tshuaj Bayet, Cmax ntawm lovastatin thiab AUC poob los ntawm 28 thiab 40%, feem. Tmax tau nce li ntawm plaub teev. Kev tswj hwm ntawm HMG-CoA reductase inhibitor nrog Bayeta tsis yog nrog cov kev hloov hauv cov ntshav lipid muaj feem xyuam (triglycerides, cov roj ntshav qis-lipoproteins, cov roj cholesterol-lipoproteins ntau, thiab tag nrho cov cholesterol).

Hauv cov neeg mob uas muaj mob ntshav me los sis mob ntshav qis, ruaj los ntawm lisinopril (5-20 mg ib hnub), Bayeta tsis hloov pauv Cmax ntawm lisinopril thiab AUC ntawm kev sib npaug. Tmax ntawm lisinopril ntawm equilibrium nce ntxiv los ntawm 2 teev. Kev hloov pauv txhua hnub txhais tau hais tias ntshav hloov diastolic systolic ntshav siab tsis tau pom.

Nrog kev qhia ntawm warfarin peb caug feeb tom qab noj Bayeta, Tmax nce ntxiv li 2 teev. Tsis pom muaj kev hloov loj hauv thaj chaw kho mob hauv Cmax thiab AUC. Kev siv Baeta txuam nrog insulin, meglitinides, derivatives ntawm D-phenylalanine, lossis alpha-glucosidase inhibitors tsis tau kawm.

Tau txais txiaj ntsig zoo los ntawm kev siv tshuaj Bayeta tsis thim cov kev xav tau kev tshuaj xyuas cov neeg mob txoj kev noj qab haus huv los ntawm cov kws tshaj lij, cov kws kho mob ntawm cov chaw kho mob, tsev kho mob, chaw kho mob, chaw kuaj mob, thiab lwm lub tsev kawm tshwj xeeb. Kev kuaj mob raws sij hawm, kev siv tshuaj tiv thaiv yuav txhim kho cov nyhuv ntawm cov tshuaj.

Cwj mem kos

Ua ntej pib siv Bayeta syringe cwj mem, ntxuav koj txhais tes. Nws yog qhov yuav tsum tau xyuas cov ntawv lo rau ntawm cov xaum xaum kom ua kom lub taub hau syringe no 5 micrograms. Tshem lub hau xiav ntawm phwj qhwv.

Koj yuav tsum tshawb xyuas cov tshuaj Bayeta hauv daim cartridge. Kev daws yuav tsum yog pob tshab, xim, tsis muaj cov hais tawm txawv teb chaws. Thaum tsis ua raws cai, tsis txhob siv lub ntsej muag xaum xaum.

Txuas ib rab koob rau ntawm xaum xaum qhuav

Nws yog ib qho tsim nyog yuav tsum tau muab daim ntawv lo rau ntawm lub hau ntim ntawm rab koob, muab rab koob nrog lub hau ntim ncaj qha rau ntawm qhov axis mus rau tus mem hluav taws xob, tom qab ntawd ntswj lub koob kom txog thaum nws kho tau ruaj. Kuaj nruj.

Nws yog ib qho tsim nyog yuav tau tshem tawm cov hau sab nraud ntawm rab koob. Lub hau yuav tsum tsis txhob muab pov tseg - nws yuav tsum tau muab tso rau ntawm qhov ntse ntawm rab koob ua ntej pov tseg. Tsis txhob muab rab koob uas tsis muaj lub hau sab nraud tso rau.

Tshem lub hau puab sab hauv thiab pov tseg ntawm nws. Hauv qee kis, qhov poob me me ntawm kev daws ntawm qhov kev npaj ntawm Baeta tshwm ntawm qhov kawg ntawm rab koob, qhov no yog qhov qub.

Dosing Baeta

Nco ntsoov tias lub cim "xub raug" tshwm sim hauv lub qhov rai ntim tshuaj. Yog tias tsis yog, tig lub koob teeb tsa lub nplhaib raws moos mus txog rau thaum nws nres, kom txog rau ntawm "xub" sab xis "cim tshwm hauv lub qhov rai koob tshuaj

Nws yog qhov yuav tsum tau rub tawm lub koob tshuaj qhov nplhaib ntawm lub koob txhaj tshuaj kom txog thaum nws nres, kom txog rau thaum lub cim xub cim tso rau hauv lub qhov rai koob tshuaj. Kev tawm ntawm lub hau yuav tsum yog ua los ntawm kev txav qeeb, tsis muaj dag zog.

Tig Baeta qhov chaw teeb tsa cov ntiv nplhaib hauv ib sab moos kom txog rau thaum "5" cim tshwm. Koj yuav tsum paub tseeb tias tus lej "5" nrog rau kab hauv qab nws nyob hauv nruab nrab ntawm lub qhov rai noj tshuaj.

Cov xaum xaum npaj

Nws yog ib qho tsim nyog yuav tsum tau tso lub xias xoos hluav taws xob hauv txoj kev uas rab koob taw thiab taw ntawm koj. Kev npaj ntawm Bayeta koob txhaj tshuaj yuav tsum tau nqa tawm hauv lub teeb txaus.

Koj yuav tsum siv tus ntiv tes xoo kom khov kho nias lub pob kom tswj hwm qhov tshuaj ntawm Bayeta kom nres, tom qab ntawd, thaum txuas ntxiv tuav lub khawm rau kev tswj hwm qhov tshuaj, maj mam suav mus rau tsib.

Kev npaj ntawm rab koob txhaj tshuaj yog txiav txim siab ua tiav yog tias lub cim "daim duab peb sab" pom nyob rau hauv nruab nrab ntawm qhov tshuaj qhov rai, ib qho trickle lossis ob peb tee ntawm cov tshuaj Bayeta tshwm ntawm qhov taub ntawm rab koob.

Ua tiav Kev Sau Se Xaj Hliav

Tig lub koob tshuaj mus rau lub moos mus txog rau thaum nws nres kom txog rau “tus xub raug” cim tso rau hauv lub qhov rai koob tshuaj.

Kev npaj ntawm koob txhaj tshuaj tshiab tiav. Tsis txhob rov ua cov kauj ruam los npaj ib cov cwj mem xaj tshiab rau kev siv txhua hnub. Yog tias qhov no tiav, Bayeta npaj yuav xaus ua ntej tas sij hawm 30 hnub ntawm kev siv.

Dosing Baeta

Tuav txoj kab ke Bayet syringe cwj mem kom nruj, ntxig rab koob rau hauv daim tawv nqaij. Thaum tswj hwm qhov koob tshuaj, siv cov txheej txheem txhaj tshuaj kom huv los ntawm cov kws kho mob koom nrog.

Siv koj tus ntiv tes xoo, khov kho nias lub koob tshuaj khawm kom nres, tom qab ntawd, thaum txuas ntxiv tuav lub koob tshuaj khawm, maj mam suav rau 5 kom tag nrho cov tshuaj nkag mus.

Qhov kev txhaj tshuaj yog suav tias yog ua tiav thaum lub cim "daim duab peb sab" tshwm sim hauv nruab nrab ntawm qhov tshuaj txhaj qhov rai. Ib rab koob txhaj tshuaj yog npaj tau rau qhov qhia ntawm koob tshuaj tshiab.

Yog tias tom qab txhaj ob peb ncos ntawm Bayeta tshuaj txau tawm ntawm rab koob, qhov no txhais tau hais tias lub koob txhaj tshuaj tsis tau nias tag nrho.

Tshem Tawm thiab Cuam Tshiav Tshuaj Koob Xaj

Ua zoo txiav lub koob tom qab txhua hno nrog tus kab mob Baeta koob txhaj. Tom qab txiav cov koob, ua tib zoo muab lub hau ntim sab nraud tso rau hauv rab koob.

Tom qab unscrewing lub koob, muab lub hau xiav ntawm Bayeta koob txhaj tshuaj ua ntej khaws cia. Kev khaws cia ntawm cov xwj xaum xaum hluav taws xob yam tsis muaj lub hau ntim yog qhov tsis tuaj yeem.

Qhov siv rab koob yuav tsum muab pov rau hauv qhov chaw tiv thaiv tiv thaiv kev tiv thaiv. Nws yog qhov yuav tsum tau ua raws li lwm cov lus pom zoo ntawm tus kws kho mob uas koom nrog.

Cov lus nug txog kev siv Bayeta Syringe Cwj mem

Kuv puas yuav tsum tau npaj tsim Bayeta syringe cwj mem tshiab rau kev siv ua ntej txhua koob?

Tsis yog. Kev npaj ntawm Bayeta koob txhaj tshuaj tshiab rau kev siv yog nqa tawm ib zaug - ua ntej nws siv. Lub hom phiaj ntawm kev npaj yog los xyuas kom meej tias Bayeta koob txhaj tshuaj yog npaj rau siv nyob rau hauv 30 hnub tom ntej. Thaum rov npaj dua lub ntsej muag tshiab, ua ntej txhua zaus ntawm Bayeta ib txwm tsis txaus rau 30 hnub. Ib qho me me ntawm Bayeta npaj noj hauv kev npaj ib rab koob xaum tshiab rau kev siv yuav tsis cuam tshuam qhov cuam tshuam 30-hnub muab kev npaj ntawm Bayeta.

Vim li cas thiaj muaj pa npuas hauv Byet cartridge?

Qhov muaj cua npuas me me hauv daim cartridge yog ib qho mob uas tsis muaj kev cuam tshuam rau koob tshuaj. Yog tus xaum xaum xaum cia nrog rab koob txuas rau nws, cov pa npuas yuav tsim tau rau hauv lub taub ntim. Tsis txhob muab xaum xaum hluav taws xob nrog rab koob txuas rau nws.

Kuv yuav ua li cas yog tias qhov kev daws ntawm Bayeta tsis tshwm sim rau qhov kawg ntawm rab koob tom qab plaub sim npaj ib rab koob tshiab tshiab rau kev siv?

Hauv qhov xwm txheej no, txiav tawm lub koob txhaj los ntawm ua tib zoo muab tso rau sab nraud ntawm rab koob, tshem tawm rab koob thiab pov tseg ntawm nws. Muab ib rab koob tshiab tso thiab rov ua cov kauj ruam los npaj ib tus cwj mem tshiab rau kev siv. Thaum ob peb ncos lossis ib qho trickle ntawm cov tshuaj daws tshwm sim thaum kawg ntawm rab koob, kev npaj ntawm koob txhaj tshuaj ua tiav.

Vim li cas cov tshuaj Bayeta ntws tawm ntawm rab koob tom qab txhaj tas?

Nws yog suav tias yog ib qho dab tsi yog tias, tom qab ua tiav ntawm kev txhaj tshuaj, qhov poob qis ntawm cov tshuaj tov dhau ntawm qhov kawg ntawm rab koob.

Yog tias ntau tshaj ib tee pom ntawm qhov kawg ntawm rab koob:

Koob tsis tau txais yam txhij. Tsis txhob noj ib qho tshuaj ua ntej sab laj nrog koj tus kws kho mob,
Txhawm rau kom tsis txhob rov tshwm sim ntawm qhov xwm txheej, rau qhov kev coj ua kom raug ntawm qhov koob tshuaj ntxiv, nias thiab tuav lub pob koob tshuaj nyob rau hauv txoj haujlwm recessed thiab maj mam suav mus rau tsib.

Kuv yuav paub tau li cas thaum Baetoy kev txhaj tshuaj tiav lawm?

Kev txhaj tshuaj yog qhov ua tiav yog tias:

Lub koob txhaj tshuaj tau raug nias thiab tuav ruaj khov rau hauv qhov chaw ua haujlwm kom txog thaum nws nres,
Thaum tuav lub pob nyem nyob hauv txoj haujlwm recessed, tus neeg mob maj mam suav mus rau tsib, rab koob thaum lub sijhawm ntawd yog tawv nqaij,
Tus cim "duab peb ceg" yog nyob hauv qhov chaw nruab nrab ntawm lub qhov rais tshuaj lub sijhawm ua haujlwm.

Kuv yuav tsum txhaj Bayeta nyob qhov twg?

Byeta txhaj rau hauv plab, ncej puab lossis xub pwg siv cov txheej txheem txhaj tshuaj uas koj tus kws kho mob pom zoo.

Kuv yuav ua li cas yog tias kuv tsis tuaj yeem rub, tig, lossis nias rau lub npov teeb liab ntawm Bayet syringe mem?

Khij lub cim hauv lub qhov rai koob tshuaj. Ua raws li cov lus qhia nyob ntawm ib sab cim.

Yog tias “xub raug” cim qhia pom hauv lub qhov rai txhaj tshuaj:

Rub lub khob tshuaj rau lub sijhawm kom txog rau thaum tus xub tso cai.

Yog tias lub cim nce xub raug pom nyob hauv koob tshuaj qhov rai thiab lub koob tshuaj lub teeb tsis tig:

Tej zaum tsis muaj tshuaj txaus nyob hauv Bayet koob txhaj tshuaj sau lub pob kom puv koob. Ib qho me me ntawm Bayeta yeej ib txwm tso rau hauv lub taub hau. Yog tias qhov tshuaj me me tso rau hauv lub taub hau lossis nws zoo li khoob, hauv qhov xwm txheej no nws yog qhov tsim nyog kom tau txais cov cwj mem tshiab Bayet syringe.

Yog hais tias lub cim “nce xub” thiab lub cim “5” raug tso rau hauv lub qhov rai tshuaj, thiab lub cim tshuaj ntaus tsis raug nias:

Lub koob teeb tsa qhov ntsuas tsis tau puv. Txuas ntxiv mus tig lub koob tshuaj lub nplhaib raws moos mus txog rau thaum "5" cim tshwm rau hauv plawv ntawm lub qhov rai tshuaj.

Yog tias lub cim “5” thiab ib feem ntawm lub cim “peb ceg” muaj ib nrab tshwm nyob rau ntawm lub qhov rais tshuaj, thiab lub cim muab tshuaj tsis tau nias:

Lub koob tuaj yeem txhaws, khoov, lossis txuas tsis raug,

Rhais qhov hno tshiab. Nco ntsoov tias rab koob tau nyob ncaj qha rau ntawm lub axis thiab raug ntsia hlau rau txhua txoj kev,
Nias lub koob tshuaj khawm kom khov kho kom txog thaum nws nres. Bayeta yuav tsum tshwm sim ntawm qhov kawg ntawm rab koob.

Yog tias lub cim qhia hauv daim duab peb sab tau tshwm sim hauv lub qhov rai koob tshuaj thiab lub nplhaib lub teeb tsa tsis tig:

Lub pob Byeta koob tshuaj tsis tau nias lub siab thiab tsis tas txhaj tshuaj. Koj yuav tsum sab laj nrog koj tus kws kho mob yuav ua dab tsi yog tias qhia txog kev siv tshuaj tsis tiav.

Cov lus qhia hauv qab no yuav tsum tau ua hauv qhov txhawm rau rov nkag tau Bayet koob txhaj tshuaj rau kev txhaj tshuaj ntxiv:

Nias lub koob tshuaj khawm kom khov kho kom txog thaum nws nres. Txuas ntxiv los tuav lub khawm koob tshuaj rau hauv txoj haujlwm recessed, maj mam suav mus rau tsib. Tom qab ntawv tig lub koob teeb tsa lub nplhaib raws moos mus txog rau "tus xub tso cai" cim tso rau hauv lub qhov rai koob tshuaj.
Yog tias koj tseem tsis tuaj yeem muab lub nplhaib teem lub tshuaj, tom qab lub koob yuav raug daig. Hloov lub koob thiab rov ua haujlwm tau piav qhia saum toj no.

Txhawm rau kom tswj hwm qhov koob tshuaj tom ntej ntawm Baeta, nias thiab tuav lub pob koob tshuaj nyob rau hauv txoj haujlwm recessed thiab maj mam suav rau tsib ua ntej tshem rab koob.

Cov lus nug txog Koob rau Syringe Cwj mem Baeta

Dab tsi ntawm qhov siv tau rab koob Kuv tuaj yeem siv nrog tus cwj mem Baeta koob txhaj?

Koob tsis muaj nyob hauv Bayet syringe mem. Txhawm rau yuav ib rab koob nyob hauv cov khw muag tshuaj, koj xav tau ntawv yuav tshuaj. Thaum siv Bayet syringe cwj mem, cov koob uas siv tau npaj rau koob txhaj tshuaj 12, 7 hli, 8 mm lossis 5 hli ntev (diam 0, 25-0, 33 mm) yuav tsum tau siv. Qhov ntev thiab taub qhov tsim nyog siv yuav tsum tau soj ntsuam nrog koj tus kws kho mob.

Kuv puas yuav tsum tau siv lub koob tshiab rau txhua txoj kev txhaj tshuaj Bayeta?

Ib rab koob tshiab yuav tsum tau siv rau txhua txoj kev txhaj tshuaj. Kev siv ntau zaus ntawm lub koob tsis tso cai. Tom qab txhaj tshuaj, rab koob yuav tsum tau txiav tawm, qhov no pab tiv thaiv cov dej xau ntawm kev daws ntawm Bayet syringe cwj mem, tsim cov pa npuas, txo qhov ua tau txhaws ntawm rab koob, thiab txo qhov kev pheej hmoo kis mob.

Tsis txhob nias lub qog koob tshuaj yog tias ib rab koob tsis txuas rau ntawm xaum xaum xaum.

Kuv yuav pov tawm cov koob li cas tom qab thov Byet?

Cov koob uas siv yuav tsum tau muab pov rau hauv lub thawv uas tiv thaiv qhov to, lossis ua raws li koj tus kws kho mob qhia. Tsis txhob pov cov xaum xaum xaim nrog cov koob txuas rau. Tsis txhob hloov xaum xaum los yog Baeta koob rau lwm tus.

Baeta Cia

Kev cia khoom ntawm Bayeta syringe cwj mem tsis siv yog nqa los ntawm cov ntawv ntim khoom qub hauv lub tub yees ntawm qhov kub ntawm 2-8 ° C, hauv qhov chaw tsaus. Thaum khaws cia rau hauv Bayeta koob txhaj tshuaj, nws yuav tsum tsis txhob txhuam. Yog hais tias qhov kev npaj tau khov thaum lub sijhawm khaws cia, nws txoj kev siv txuas ntxiv yog tso cai.

Thaum siv, Bayeta syringe cwj mem yuav tsum khaws cia qhov kub tsis tshaj 25 ° C rau tsis pub dhau 30 hnub.

Tsis txhob khaws lub Byeta cwj mem syringe nrog rab koob txuas. Yog tias rab koob raug tso rau tom qab lawm, qhov kev daws teebmeem ntawm cov tshuaj Bayeta tuaj yeem nqus tawm ntawm lub ntsej muag hauv lub tes, cov pa npuas tuaj yeem ua rau sab hauv lub taub hau.

Tso Cia ntawm Byet yog cov me nyuam siv tsis tau.

Txee lub neej ntawm Baeta yog 24 lub hlis txij li hnub tso tshuaj tawm.

Baeta thiab Victoza

Kev npaj Bayeta thiab Viktoza yog cov ua kom zoo zuj zus ntxiv, yog tsim nyob rau hauv cov kua roj ntsha rau kev coj ua, thiab yog siv rau kev kho mob hom 2 mob ntshav qab zib mellitus. Kev siv cov kev cai rau cov tshuaj no pab txo glycated hemoglobin los ntawm 1-1, 8% thiab poob ceeb thawj los ntawm plaub mus rau tsib kilo rau 10-12 lub hlis ntawm kev siv. Txawm hais tias muaj ntau qhov kev txwv dav dav, thiab cov txheej txheem ntawm kev txiav txim ntawm Viktoza thiab Byet, kev teem sijhawm ntawm ib cov tshuaj tshwj xeeb tseem nyob hauv kev paub ntawm tus kws kho mob.

Nqe Baeta (Exenatide)

Tus nqi ntawm Exenatide Baeta Syringe Pens tsis suav cov nqi thauj khoom yog tias cov tshuaj yuav los ntawm khw muag tshuaj online. Tus nqi yuav txawv txav raws qhov chaw yuav khoom thiab ntau npaum li cas.

Lavxias (Moscow, St. Petersburg) los ntawm 3470 txog 6950 Lavxias teb sab rubles,
Ukraine (Kiev, Kharkov) los ntawm 1145 rau 2294 Ukrainian hryvnias,
Kazakhstan (Almaty, Temirtau) los ntawm 16344 txog 32735 Kazakhstan tenge,
Belarus (Minsk, Gomel) los ntawm 912610 txog 1827850 Belarusian rubles,
Moldova (Chisinau) los ntawm 972 txog rau 1946 Moldovan Lei,
Kyrgyzstan (Bishkek, Osh) los ntawm 3,782 txog 7,576 Kyrgyz soms,
Uzbekistan (Tashkent, Samarkand) los ntawm 134567 txog 269521 Uzbek soums,
Azerbaijan (Baku, Ganja) los ntawm 51.7 txog 103.6 Azerbaijani manats,
Armenia (Yerevan, Gyumri) los ntawm 23839 txog 47747 Armenian koob tshuaj,
Georgia (Tbilisi, Batumi) los ntawm 118.0 txog 236.3 Georgian lari,
Tajikistan (Dushanbe, Khujand) los ntawm 326.9 txog 654.7 Tajik somoni,
Turkmenistan (Ashgabat, Turkmenabat) los ntawm 167.6 txog 335.7 tus txiv neej tshiab Turkmen.

Yuav Baeta

Yuav Koj tuaj yeem siv cov tshuaj hauv Bayeta koob txhaj tshuaj ntawm lub tsev muag tshuaj uas siv cov kev pabcuam tswj chaw muag tshuaj, suav nrog tos. Ua ntej koj yuav Bayeta, koj yuav tsum qhia meej lub sijhawm tas sij hawm ntawm cov tshuaj. Koj tuaj yeem xaj tau Byet ntawm cov khw muag tshuaj muaj nyob hauv online, kev muag yog nqa nrog kev xa khoom, raws li kev tshaj tawm ntawm kws kho mob sau.

Siv Cov Ntawv Piav Qhia Baeta

Cov lus piav qhia ntawm cov tshuaj ntshav hypoglycemic Bayeta (Exenatide) ntawm kev kho mob portal My Pills yog cov ncauj lus kom ntxaws version "Cov lus qhia rau kev siv tshuaj Byet"Cov. Ua ntej yuav thiab pib siv cov tshuaj, koj yuav tsum paub koj tus kheej nrog cov lus qhia pom zoo los ntawm cov kws tsim khoom, sab laj nrog tus kws tshaj lij kho mob, kws kho mob. Cov lus piav qhia ntawm cov tshuaj Bayeta (Exenatide) tsuas yog muab rau cov ntaub ntawv xov xwm nkaus xwb thiab tsis yog kev qhia siv rau kev kho tus kheej.