Cov tshuaj tsis kho mob ntshav qab zib

Glidiab yog tshuaj yeeb tshuaj hypoglycemic, uas hais txog lub cim thib ob sulfonylurea derivatives. Nws raug nquahu rau kev kho mob thib ob ntawm cov kabmob qab zib ua ke nrog kev noj zaub mov zoo rau lub cev thiab kev tawm dag zog.

Cov tshuaj noj pab txo cov ntshav qab zib kom tsawg thiab ruaj khov rau ntawm qib. Tsis tas li ntawd, kev siv cov tshuaj muab ib qho kev nce ntxiv hauv kev ua haujlwm ntawm kev noj zaub mov zoo nyob rau hauv ib qho xwm txheej uas cov neeg mob ntshav qab zib yog qhov hnyav dua lossis rog dhau.

Koj tuaj yeem yuav cov tshuaj hauv khw muag tshuaj lossis chaw muag tshuaj kiosk. Tus nqi ntawm ib qho tshuaj txawv ntawm 130 txog 200 rubles, thiab nyob ntawm qhov muaj tshuaj ntau hauv cov ntsiav tshuaj. Glidiab 80 thiab 30 mg yog muag.

Nws yog ib qho tsim nyog yuav tau xav txog dab tsi contraindications thiab phiv cov tshuaj muaj, thiab yuav ua li cas noj nws kom raug? Qhov tshuaj xyuas ntawm Glidiab yog dab tsi, thiab cov neeg mob ntshav qab zib hais dab tsi?

Lub hauv paus ntsiab lus ntawm cov tshuaj

Cov tshuaj rau kev kho mob "qab zib" ntawm hom thib ob yog muaj nyob hauv ntsiav tshuaj daim ntawv, cov tshuaj tseem ceeb ntawm cov tshuaj yog glyclazide. Cov tshuaj ntawm cov ntsiav tshuaj suav nrog cov khoom siv ntxiv - microcrystalline cellulose, magnesium stearate thiab lwm yam tshuaj.

Cov lus luv "MV", muaj nyob rau hauv lub npe tshuaj, sawv cev rau kev hloov kho tawm. Kev tshuaj xyuas ntawm tus kws kho mob tau lees tias qhov nuance no tso cai rau koj yuav tsum noj cov tshuaj ib hnub ib zaug.

Cov khoom tseem ceeb thaum lub sij hawm nqus tau pab txhawb qhov kev ua ntawm cov leeg glycogen synthetase thiab kev tsim tawm ntawm cov tshuaj insulin hauv lub cev. Tsis tas li ntawd, cov ntsiab lus tseem ceeb txiav txim siab txog insulin secretory kev txiav txim siab ntawm qab zib, ua rau muaj kev cuam tshuam ntau ntxiv rau nws ntawm qib ntawm tes.

Ntawm qhov tsis muaj qhov tseem ceeb yog qhov tseeb tias Glidiab ntsiav tshuaj pab txo lub sij hawm nruab nrab ntawm kev siv khoom noj thiab pib ua haujlwm nquag ntawm insulin. Ceeb toom rau cov cuab yeej qhia tau hais tias kev siv cov tshuaj txo qis ntawm qhov siab ntawm lub xeev hyperglycemic, thaum muaj kev rov kho dua ntawm qhov ua tiav thaum ntxov ntawm kev ua cov tshuaj hormone.

Tag nrho cov yam ntxwv saum toj no muaj qhov cuam tshuam ncaj qha rau kev zom cov zaub mov carbohydrate thiab microcirculation. Kev siv cov tshuaj Glidiab txo qis kev pheej hmoo ntawm kev txhim kho atherosclerotic hloov pauv ntawm cov hlab ntsha.

Vim tias qhov peculiarities ntawm daim ntawv noj tshuaj, ib koob tshuaj ib hnub tau lees tias ib qho kev kho mob zoo ntawm cov tshuaj nquag nyob hauv ntshav rau 24 teev.

Cov kev thaiv tsis zoo thiab cov tshwm sim

Ntawm Glidiab MV, cov lus qhia rau kev siv lub xeev tias cov tshuaj muaj cov npe meej txog kev tsis sib haum xeeb uas txiav txim siab qhov tsis txaus ntseeg ntawm cov tshuaj hauv qee yam xwm txheej.

Koj tsis tuaj yeem siv tshuaj ntsiav rau kev kho mob los ntawm hom 1 mob ntshav qab zib mellitus, nrog rau tus mob ntshav qab zib lossis hyperosmolar coma, yog tias muaj keeb kwm ntawm lub plab paresis, mob plab hnyuv, nrog rau cov xwm txheej uas nrog los ntawm kev loj hlob ntawm hypoglycemia.

Tsis tas li ntawd, Glidiab MB yog contraindicated rau hauv cov xwm txheej nram qab no: tsis kam mus rau cov tshuaj raws li tag nrho lossis nws cov khoom siv, kev raug mob dav, kev phais mob, kev tsis txaus siab lub siab thiab lub raum kev ua haujlwm, lub sijhawm ntawm kev xeeb tub thiab lub sijhawm pub mis.

Cov tshuaj Glidiab tuaj yeem ua rau cov kev mob tshwm sim hauv lub cev:

• Kev tsis sib haum xeeb hauv cov hlab plawv thiab cov ntshav ncig: mob ntshav siab, ntshav liab.
• Hog ntshav qab zib hauv lub xeev (ntau cov ntshav qab zib tsawg), ua kom qab los, tsis muaj zog, nkees, qaug zog, tawm hws, mob taub hau thiab kiv taub hau.
• Kev mob siab ntsws ntsws, tsis txaus ntseeg kev chim siab thiab kev tawm tsam, kev tsis haum.
• Kev kub ntxhov ntawm qhov kawg, ua rau lub xeev tsis meej, mob leeg thiab mob sib koom tes, pom kev tsis sib haum xeeb, lub plawv dhia ceev ceev.
• Ua txhaum ntawm lub hnyuv thiab lub plab zom mov.
• Kev tawm tsam ua xua nrog cov tsos mob ntawm daim tawv nqaij - ua pob liab liab rau ntawm daim tawv nqaij, ua pob liab vog, urticaria, hlawv qhov hnov.

Nrog rau kev siv tshuaj ntau dhau, qhov kev txhim kho ntawm qhov mob ntshav qab zib tsawg, uas tuaj yeem ua rau mob ntshav qab zib tsis xeev, tsis tau txiav txim siab.

Cov lus qhia rau kev siv ntsiav tshuaj

Kev Tshaj Tawm ntawm cov tshuaj Glidiab MB qhia tau hais tias cov tshuaj tau pom zoo rau kev kho mob ntshav qab zib mellitus nrog kev ua kom lub cev zoo.

Raws li txoj cai, cov tshuaj ib txwm ua yog cov txhais tau tias tsuas txo qis ntshav qab zib. Tsuas yog hauv qee kis tshwj xeeb nws tuaj yeem pom zoo hauv kev kho mob kis tau tus kab mob. Piv txwv, hauv kev sib xyaw nrog kev npaj los ntawm cov pab pawg biguanide.

Qhov ntau npaum ntawm cov tshuaj yog tshuaj raws li ntsuas ntawm qab zib cov ntsiab lus ntawm ib plab khoob, nrog rau ob teev tom qab noj mov.

Ntawm Glidiab, cov lus qhia rau kev siv muab cov ncauj lus nram qab no:

1. Cov ntsiav tshuaj raug pom zoo kom noj ib hnub ib zaug, lub sijhawm noj su yog sawv ntxov ua ntej noj mov.
2. Qhov nruab nrab, cov tshuaj rau ib hnub yog 80 mg, suav nrog rau cov neeg mob laus (tshaj 65).
3. Yog hais tias kho qhov ua tau zoo tsis txaus, nws raug tso cai kom maj mam nce cov tshuaj nrog rau ib ncua sijhawm ntawm 14 hnub.
4. Qhov ntau kawg noj rau ib hnub tsis ntau tshaj 320 mg.

Yog tias tus neeg mob tau ua rau lub siab thiab lub raum tsis ua haujlwm, ces yuav tsum tau txhaj koob tshuaj ntawm Glidiab MV tsis tas yuav.

Tus nqi ntawm cov tshuaj, qhov ntim ntawm cov tshuaj yog 80 mg (60 ntsiav tshuaj ib pob) yog 134 rubles. Tus nqi ntawm 60 ntsiav tshuaj hauv qhov tshuaj ntawm 30 mg yog 130 rubles. Glidiab MB yog me ntsis kim kim, tus nqi yog rau 60 pcs. 80 mg txhua yog 185 rubles.

Analogues ntawm cov tshuaj

Hauv ntau qhov xwm txheej, Glidiab tsis pom zoo kom sau ntawv vim tias muaj qhov sib txuam ntawm qhov sib txuam, qhov kev pheej hmoo siab ntawm cov kev mob tshwm sim los ntawm lub hauv nruab nrab ntawm cov hlab ntsha thiab cov hlab plawv.

Hloov cov tshuaj nrog rau ib los yog lwm cov tshuaj yuav tsum tau nqa tawm tshwj xeeb los ntawm tus kws kho mob mus koom, tsis muaj dab tsi ntxiv.

Cia peb xav txog cov analogues hauv kev nthuav dav ntxiv:

• Formmetin yog cov tshuaj uas pom zoo rau kev kho mob ntshav qab zib hom 2 thaum kev noj zaub mov ua kom tsis muaj txiaj ntsig. Nws feem ntau pom zoo ua ke nrog cov tshuaj uas yog sulfonylurea derivatives.
• muaj lub ntsiab tseem ceeb tshuaj glibenclamide, yog sulfonylurea derivatives. Cov tshuaj txhawb cov nquag tsim tawm ntawm cov tshuaj insulin, muab cov insulin-excreting effect ntawm cov piam thaj.
• Glibenclamide yog tshuaj rau tus mob ntshav qab zib zaum ob, thaum nws tsis tuaj yeem them nyiaj rau cov kab mob pathology los ntawm kev noj haus thiab kis las. Qhov ntau npaum li cas yog tshuaj raws li cov piam thaj ntsuas, nws tuaj yeem sib txawv ntawm 2.5 txog 15 mg. Tshaj tawm ntawm kev siv ntau zaus hauv ib hnub.
• Amaryl - ib tus neeg sawv cev hypoglycemic, yog raug kho rau kev kho mob ntawm hom thib ob ntawm kev kho mob tsuas yog siv tshuaj los yog muaj kev sib xyaw nrog insulin lossis metformin. Raws li txoj cai, kev kho mob nrog cov tshuaj no siv sijhawm ntev.

Cov tshuaj Glidiab thiab nws cov analogues ua tau zoo ntawm kev kho "kab mob". Txawm li cas los xij, nrog rau cov khoom zoo, lawv muaj contraindications thiab phiv. Yog li, kev teem caij yuav tsum ua los ntawm tus kws kho mob nkaus xwb.

Kev noj tshuaj pab ua rau lub cev txo cov ntshav qabzib ntau thiab ruaj khov rau ntawm qib uas xav tau. Tab sis, txhawm rau txhawm rau txhim kho txoj kev ua tau zoo ntawm kev siv tshuaj, tus neeg mob yuav tsum ua raws li kev noj haus thiab kev tawm dag zog kom nce qhov rhiab ntawm cov nqaij mos kom ua kom qabzib.

Koj xav li cas txog qhov no? Koj tus kws kho mob muab tshuaj dab tsi rau koj noj, thiab koj tuaj yeem qhia nws dab tsi los ntawm qhov pom ntawm koj tus kheej qhov kev paub dhau los?

1 ntsiav tshuaj suav nrog 80 mg gliclazideCov. Txuas ntxiv: mis nyuj qab zib, magnesium hydrosilicate, microcrystalline cellulose, hydroxypropyl methyl cellulose, qos hmoov txhuv nplej siab, sodium starch glycolate, magnesium stearate.

1 ntsiav tshuaj ntawm MB (hloov tawm tso tawm) suav nrog 30 mg gliclazideCov. Ntxiv: hydroxypropyl methylcellulose, aerosil, microcrystalline cellulose, magnesium stearate.

Ntshav qab zib-hom carbohydrate metabolism cuam tshuam

Tau ntau xyoo tsis muaj kev vam meej nrog DIABETES?

Lub taub hau ntawm lub koom haum: “Koj yuav xav tsis thoob tias yoojyim kho mob ntshav qab zib li cas los ntawm kev noj tshuaj txhua hnub.

Hauv cov neeg mob ntshav qab zib muaj hnub nyoog 41-50 xyoo, qhov xwm txheej no tau tsim nyob rau hauv 11.3% ntawm tus neeg mob, thiab thaum muaj hnub nyoog 51-60 xyoo - nyob rau hauv 39.7% ntawm tus neeg mob. Ntxiv mus, nws tuaj yeem raug sau tseg tias ntawm cov neeg mob ntshav qab zib uas peb tau pom, 16 pom hluav taws xob hloov pauv tom qab myocardial infarction, thiab tsis muaj qhov qhia tias muaj angina pectoris hauv keeb kwm ntawm cov neeg mob. Ntawm 27 tus neeg mob myocardial infarction nrog ntshav qab zib, cov ntaub ntawv tuag uas peb tau muab rau saum toj no, tsis muaj mob rau myocardial infarction tau sau tseg hauv 5 tus neeg mob.

Tam sim no, cov neeg tuaj kho mob tau paub zoo txog cov ntshav qab zib-hom carbohydrate metabolism cuam tshuam, thawj zaug kuaj tau hauv cov neeg mob thaum tus mob myocardial infarction. Hauv qee qhov xwm txheej no, glycosuria thiab hyperglycemia muaj ntau dua los yog tsawg dua li qub, cov neeg mob xav tau kev noj haus thiab tshuaj kho cov kab mob ntawm cov kab mob ntawm cov kab mob metabolism thiab ntev ntev tom qab myocardial infarction. Hauv cov xwm txheej zoo li no, nws yuav tsum xav tias qhov tsis txaus ntseeg txhim kho txoj hlab ntsha tsis txaus ua rau muaj kev hloov pauv ntawm cov mob ntshav qab zib latent mus rau thaj chaw kho mob. Raws li rau cov neeg mob nyob rau hauv uas myocardial infarction sawv nyob rau hauv tej yam kev mob ntawm twb tshwm sim ntshav qab zib mellitus, tsis zoo ntawm carbohydrate metabolism tam sim ntawd tom qab qhov pib ntawm mob ischemic tshwm sim yog pom ntau heev (A.R. Zlotopolsky thiab A.I. Khazanov, 1963, S. A. Sideraite thiab XX Kibarskis, 1964, Nielsen, 1967, D.F. Presnyakov thiab A.M. Kostenboim, 1970, thiab lwm yam).

Cov lus nug txog qhov tseem ceeb ntawm kev kho tshuaj insulin hauv kev kho mob ntawm cov mob atherosclerosis thiab mob plawv yog tsis tau xav txog nyob hauv cov ntsiab lus no, txawm li cas los xij, qee qhov kev sim ua kom nws ua tau rau nws.

Cov zaub mov regimen atheromatosis

Pick et al. (1959) muaj cov txiv neej tom qab txiav ib feem ntawm tus kab mob pancreatectomy hauv cov zaub mov uas muaj cov roj (cholesterol), ua kom muaj cov atheromatosis hauv txoj kev no. Tom qab hloov cov txivneej mus rau cov kab mob kev noj zaub mov kom zoo, atheromatosis sai sai ploj, tab sis kev tswj hwm ntawm cov tshuaj insulin ua rau qeeb qeeb kev txhim kho ntawm atheromatosis. Hauv kev sim ntawm O. N. Voskresensky (1962), hauv kev tsis sib thooj, insulin txo qis kev hloov pauv thaum kev sim yug me nyuam ntawm atheromatosis hauv luav. Cov ntawv pov thawj tseem ceeb tiv thaiv lub luag haujlwm ntawm cov kua dej los yog qhov tseem ceeb hauv qhov pathogenesis ntawm atherosclerosis yog muab los ntawm cov ntaub ntawv hauv chaw soj ntsuam thiab ntu. Liebow et al. (1955), Perrin et al. (1962), Otto et al. (1964), Nielsen (1967) hauv kev txheeb xyuas tshwj xeeb tsis tau tsim kev sib txawv ntawm qhov mob loj ntawm atherosclerosis ntawm cov neeg mob ntshav qab zib kho cov tshuaj insulin, sulfonamide lossis kev noj zaub mov noj xwb Cov.

EG Moskovich (1958), Azerad et al. (1963) piv rau lub sijhawm ntawm kev kho tshuaj insulin thiab kev txhaj tshuaj insulin nrog qhov mob hnyav ntawm cov chaw kuaj mob thiab electrocardiographic kev mob ntawm cov mob ntshav siab ntshav hauv cov neeg mob ntshav qab zib thiab tsis pom muaj kev sib thooj. Thaum kawg, qhov tseeb tias cov neeg mob ntshav qab zib tau txais insulin tau ntau xyoo tsis muaj cov cim ntawm kev mob caj dab lossis lwm yam mob atherosclerosis, thiab hauv cov neeg mob uas laus dua 40 xyoo, muaj ntau zaus ntawm cov chaw kho mob thiab electrocardiographic pov thawj ntawm cov leeg txha caj qaum txhawm rau raug tshawb pom nrog txhua yam kev kho, ua rau muaj kev tsis ntseeg ntawm cov kab mob atherogenic ntawm insulin.Qhov xwm txheej yog qhov cuam tshuam ntau dua nrog kev cuam tshuam cov tshuaj insulin rau ntawm electrocardiogram thiab kev siv tshuaj insulin rau hauv cov neeg mob ntshav qab zib nrog mob tsis txaus. Qee qhov kev tshawb fawb tau ceeb toom txo qis dua nthwv dej T, hloov chaw thiab hloov pauv hloov qhov sib txawv ntawm 5-T ntawm qhov raug ntawm electrocardiogram tom qab kev saib xyuas ntawm insulin rau ob leeg tib neeg tsis muaj ntshav qab zib (Mitschke, 1966) thiab cov neeg mob ntshav qab zib mellitus (A. I. Romanov, 1964, N I. Meshalkina, xyoo 1964, Mitschke, 1968).

Cov tshuaj muaj pes tsawg leeg

Hauv cov khw muag tshuaj network Glidiab (hauv daim ntawv thoob ntiaj teb - Glidiab) tuaj yeem muas tau hauv cov qauv ntsiav tshuaj rau kev siv ncauj. Ib qho kev sib xyaw tshwj xeeb thiab cov thev naus laus zis tshiab rau kev tswj hwm tus nqi ntawm qhov hloov kho tawm ntawm cov tshuaj nquag. Cov xim xim yog multivariate: dawb, daj, qab zib.

Ntawm ib lub blister hauv lub contour hlwb, 10 ntsiav tshuaj hnyav 80 mg tau muab ntim nrog cov khoom xyaw gliclazide nquag. Nws yog ntxiv nrog cov zam ntxiv: cov hmoov txhuv nplej siab, magnesium stearate, sodium starch glycolate, mis qab zib, hypromellose, MCC, talc.

1 ntsiav tshuaj ntawm cov tshuaj Glidiab MV muaj 30 mg ntawm gliclazide. Nws yog ntxiv los ntawm MCC, hypromellose, magnesium stearate, aerosil.

Pharmacological tau

Tsis zoo li cov kab ua ntej dhau los ntawm cov tshuaj, Glidiab tsis muaj tshuaj lom tsawg dua thiab muaj txiaj ntsig zoo dua, thiab nws cov yam ntxwv hypoglycemic yog ua raws li qhov tseeb uas nyob hauv qab ntawm Glidiab:

• Ua kom cov insulin ntau ntxiv los ntawm β-hlwb,
• Kev tsim cov hepatic glycogen yog tshuab txais,
• Receptor cov roj ntsha inhibit gluconeogenesis,
• Endogenous insulin kev ua si tau txhim kho,
• Cov synthesis ntawm qabzib los ntawm cov protein thiab cov rog nyob rau hauv lub siab yog sim,
• Lub siab thiab cov leeg pob txha nqus cov piam thaj ntau nquag,
• Ua kom qis qis lipolysis hauv cov ntaub so ntswg.

Txog Glidiab, kev tshuaj xyuas ntawm cov kws kho mob hais rau peb tias nrog rau kev siv tshuaj, kev tawm tsam insulin ntawm peripheral cov ntaub so ntswg txo, cellular enzymes, hauv glycogen synthetase tshwj xeeb, ua kom lub cev, lub sij hawm nruab nrab ntawm cov zaub mov thiab insulin nce yog txo.

Piv rau lwm cov tshuaj ntawm sulfonylurea pab pawg (glibenclamide, chlorpropamide), uas ua haujlwm feem ntau nyob rau theem ob ntawm cov tshuaj tua hluav taws xob, glycoslide pab ua kom lub zog thaum kawg ntawm cov tshuaj insulin thiab txo glycemia tseem ceeb. Ntxiv rau kev ua kom lub cev tsis ua haujlwm zoo, cov tshuaj kho txhim kho capillary ntshav txaus, txo cov platelet adhesion thiab kev sib sau ua ke, thiaj li tso tseg kev tsim cov quav hniav.

Raws li cov lus qhia, gliclazide:

• Kho txhim kho vascular permeability thiab elasticity,
• Siv los tiv thaiv microthrombosis,
• Nws ua rau lub rhiab heev ntawm cov hlab ntsa rau adrenaline,
• Restore physiological fibrinolysis (ntxuav los ntawm ntshav txhaws),
• Nws txo cov ntsiab lus ntawm cov roj (cholesterol) tag nrho, muaj cov tshuaj tiv thaiv atherogenic (tiv thaiv thiab regression ntawm atherosclerosis),
• Ncua kev nce qib ntawm retinopathy nyob rau theem tsis-loj zuj zus.

Siv lub sijhawm ntev dua ntawm Glidiab los ntawm cov neeg mob ntshav qab zib nrog nephropathy txhim kho kev ua kom cov protein ntau hauv cov zis. Cov tshuaj tsis pab txhawb rau qhov hnyav ntxiv, vim tias nws cov haujlwm tseem ceeb yog nyob rau thaum ntxov tshaj plaws ntawm kev tsim cov tshuaj insulin, uas tsis ua rau hyperinsulinemia. Cov tshuaj tso cai rau cov rog ntshav qab zib rau qee yam uas poob phaus, raug rau kev ua neej hloov kho.

Pharmacokinetics ntawm cov tshuaj

Kev ntsuas ntawm kev nqus ntawm gliclazide nyob rau hauv lub plab zom mov tom qab qhov ncauj tswj hwm ntawm cov tshuaj yog siab. Kev noj ib koob ntawm cov tshuaj (80 mg) muab qhov siab tshaj plaws ntawm cov kev ua haujlwm hauv cov ntshav ntshav tom qab 4 teev. Cov tshuaj txiav txim siab nyob hauv daim siab yog biotransformed: oxidation, hydroxylation thiab glucuronidation ua rau tsim cov 8 metabolites uas tsis nyob nruab nrab nrog rau kev ua kom qabzib. Ib qho ntawm cov tshuaj metabolites muaj peev xwm cuam tshuam rau microcirculation. Cov khoom noj tsis zoo ua rau lub raum (70%) thiab txoj hnyuv (12%). Hauv nws daim ntawv qub, tsuas yog 1% ntawm Glidiab yog tshem tawm.Qhov kev tshem tawm ib nrab-lub neej yog tsau nyob rau hauv thaj tsam ntawm 8-11 teev.

Leej twg yog tus muab tshuaj Glidiab

Glidiab raws li cov lus qhia raug rau kev siv yog pom zoo rau cov neeg mob ntshav qab zib nrog hom 2 mob ntawm cov mob nyhav, thaum muaj teeb meem xws li microangiopathy twb tau tsim. Nws raug tso cai siv cov tshuaj rau kev kho mob monotherapy lossis hauv kev kho mob nyuaj, nrog lwm cov tshuaj tiv thaiv hypoglycemic. Glidiab yog tshuaj noj nrog rau lwm cov tshuaj rau ntshav qab zib kom tiv thaiv hemorheological teeb meem ntawm ntshav qab zib.

Hauv txhua kis, cov tshuaj tau muab tshuaj nrog kev ua haujlwm tsis txaus ntawm kev kho tsis siv tshuaj lossis ntxiv rau kev hloov kho hauv lub neej.

Muaj peev xwm ua mob tau los ntawm gliclazide

Glyclazide-raws li cov tshuaj yog contraindicated:

• Tus mob ntshav qab zib hom 1,
• Nrog labile kev loj hlob ntawm hom 2 mob ntshav qab zib,
• Nrog ketoacidosis,
• Cov neeg mob nrog insuloma
• Nyob rau hauv cov kev mob uas provoke precom thiab ntshav qab zib,
• Cov neeg mob raum thiab mob siab tsis txaus,
• Nrog rau mob microangiopathy,
• Tus mob ntshav qab zib nrog qhov tsis haum rau sulfonylureas
• Nyob rau lub sijhawm cov kis kab mob,
• Thaum cev xeeb tub thiab lactation,
• Hauv thaum yau (tsis muaj ntaub ntawv hais txog cov txiaj ntsig thiab kev nyab xeeb),
• 48 teev ua ntej thiab tom qab phais loj.

Yuav thov cov tshuaj

Ua ntej teeb tsa kev kho mob, tus kws kho mob soj ntsuam cov xwm txheej ntawm tus neeg mob, hnub nyoog, theem ntawm tus kab mob, thiab cuam tshuam nrog cov kev cuam tshuam. Raws li qhov ntsuas ntawm kev yoo mov thiab postprandial glycemia, nrog rau cov tshuaj muaj lwm cov tshuaj tiv thaiv kab mob uas tus neeg mob siv sib luag, qhov nqi niaj hnub ntawm Glidiab yog xam. Tus neeg mob qhov kev tawm tsam tus neeg rau cov tshuaj tseem raug suav nrog.

Rau cov tshuaj ib txwm ua

Txhawm rau Glidiab yooj yim, cov lus qhia rau kev siv pom zoo pom zoo ib koob ntawm cov tshuaj - 80 mg / hnub., Qhov nruab nrab - 160 mg, siab tshaj plaws - 320 mg. Siv ob: thaum sawv ntxov thiab yav tsaus ntuj, 1 ntsiav tshuaj ua ntej noj mov. Hauv raum pathologies, yog tias creatinine tshem tawm yog tsawg dua 15 units, kev hloov kho koob tshuaj yog tsis tsim nyog.

Rau variant Glidiab MV

Hauv cov neeg mob ntshav qab zib (suav nrog hom kab mob gerontological), tus qauv ntawm cov tshuaj uas muaj lub zog ntev ntawm qhov pib kawm yog 30 mg. Kev kho ntawm cov qauv yog tau tom qab 14 hnub. Qhov ntau kawg ntawm qhov Glidiab MV, raws li cov lus qhia rau kev siv, yog 120 mg / hnub. Qhov no sib haum rau 4 pcs. ntsiav tshuaj. Cov tshuaj yog coj qhov ncauj nrog pluas tshais. Nws raug tso cai coj lwm tus neeg sawv cev hypoglycemic nyob rau hauv parallel: biguanides, α-glucosidase enzyme inhibitors, insulin.

Yam tsis tau xav txog

Txog Glidiab kev txheeb xyuas qhia tias qee kis, kev kho yog nrog cov xwm txheej tsis paub txog.

Cov neeg mob ntshav qab zib yws yws txog kev qaug zog, kiv taub hau, mob taub hau, pancytopenia, ua xua, ua pob khaus, ua kom tawv nqaij, muag duab, ua kom mob plab, ua kom tsis haum plab, mob ntsws tsis nco qab, ua kom tsis nco qab zoo, mob plab, raws plab.

Cov mob uas tsis tshua pom muaj yog hypoglycemia, paresis, thrombocytopenia, leukopenia, agranclocytosis, anemia. Feem ntau, tag nrho cov kev mob tshwm sim yuav thim rov qab: tom qab tsis txiav cov tshuaj, lawv ploj lawv tus kheej.

Txhawm rau kom tsis txhob mob ntshav qab zib thiab lwm yam kev tsis txaus siab, nws yog ib qho tseem ceeb kom meej meej txog sijhawm siv cov ntsiav tshuaj rau kev noj zaub mov, kom tsis txhob tshaib plab thiab tshem tawm cov cawv los ntawm kev noj zaub mov kom tiav.

Kev Yeeb Tshuaj Sib Tham nrog Glidiab

Noj ntau dhau

Nrog rau qhov nce ntxiv hauv cov koob tshuaj ntau dua dhau los kho kev mob, muaj peev xwm ua rau muaj qhov txo qis tseem ceeb hauv glycemic. Kev haus ntau dhau lawm tuaj yeem pab txhawb kev txhim kho ntawm glycemic coma. Yog hais tias tus neeg raug tsim txom nco qab thiab tuaj yeem nqos cov ntsiav tshuaj, nws tau muab sucrose, dextrose, piam thaj lossis tsuas yog cov khoom noj qab zib (tsis muaj khoom qab zib).

Hauv cov neeg mob tsis nco qab lawm, cov tshuaj tau muab tshuaj tso ntshav (40% dextrose) lossis intramuscularly (1-2 g ntawm glucagon). Tom qab rov nco qab, tus neeg raug tsim txom yuav tsum tau muab cov roj sai sai rau txoj kev tiv thaiv kom tsis txhob rov huam mob.

Dosage daim ntawv

Cov tshuaj noj hauv qhov ncauj hauv cov khw muag tshuaj tuaj yeem nqus tau hauv daim ntawv ncoo. Nws yog tsim tawm ua ob hom: Glidiab zoo tib yam (6 daim hlau ntawm 10 pcs. Ib pob) thiab Glidiab MV, ua cim los ntawm kev hloov pauv ntawm cov tshuaj nquag (3 lossis 6 daim hlau ntawm 10 pcs. Hauv ib lub thawv).

Ntawm kev yooj yim Glidiab tus nqi yog pheej yig heev - 106-136 rubles. rau 60 ntsiav tshuaj ntawm 80 mg. Ntawm Glidiab MV, tus nqi hauv khw muag tshuaj online yog me ntsis siab dua: 160-166 rubles. rau 60 ntsiav tshuaj ntawm 30 mg.

Cov cai cia

Glidiab tsis tas yuav muaj cov xwm txheej tshwj xeeb. Cov khoom siv xub thawj yuav tsum tau muab tso kom deb ntawm qhov chaw tiv thaiv huab cua, ua kom muaj hluav taws xob ultraviolet thiab saib xyuas cov menyuam yaus, cov tsiaj yug hauv tsev thiab cov neeg xiam oob khab. Kev ntsuas kub thiab txias - txog 25 ° С. Cov ntsiav tshuaj siv nyob rau hauv lub sijhawm tas sijhawm: 4 xyoos rau cov tshuaj Glidiab thiab 1 xyoo rau nws qhov hloov kho ntawm Glidiab MV. Thaum kawg ntawm lub sijhawm tas sijhawm teem los ntawm cov kws tsim khoom, cov tshuaj yuav tsum tau muab pov tseg, vim tias nws cov haujlwm tau txo qis, thiab tus lej ntawm cov kev mob tshwm sim tau loj tuaj.

Cov Cov Txhais Lus thiab analogues ntawm Glidiab

Cov tshuaj qub yog Gliclazide nrog tib yam tshuaj muaj sia, txhua tus so yog generics. Glidiab hauv qeb duas yog suav tias yog qhov ua tau zoo tshaj plaws. Hais txog cov tshuaj tiv thaiv nquag (gliclazide) thiab pawg (cov tshuaj tiv thaiv kab mob hauv qhov ncauj), cov tshuaj noj nrog Glidiab yog cov zoo ib yam: Gliclazide, Diagnizid, Diatika, Diabinax, Diabefarm, Diabresid, Diabetalong, Glioral, Predian, Gliclada, Glucostabil, Diabeton Panmicron, Gluktam, Glisid, Medoklazid.

Ntawm cov analogues uas kev teem caij yog tib yam (hom 2 mob ntshav qab zib), feem ntau nrov yog: Lymphomyozot, Januvia, Multisorb, Bagomet, Glemaz, Metamin, Baeta, Apidra, Glyurenorm, Formmetin, Glyukobay, Novoformin, Levemir Flekspen, Formin, Levemir Penfill, Avavia, Pioglar.

Cov lus pom zoo ntxiv

Qhov tshwm sim ntawm kev kho mob nrog Glidiab yuav qis dua yog tias tsis muaj kev hloov pauv ntawm cov ntshav qab zib lub neej: kev noj haus tsis zoo, kev tawm dag zog lub cev, tswj lub cev hauv lub siab, ua raws li kev pw tsaug zog thiab so kom txaus.

Nws yog ib qho tseem ceeb uas yuav tsum tau saib xyuas koj cov glycemic profile tas li los ntawm kev txheeb xyuas qib hauv cov suab thaj hauv tsev thiab hauv chav kuaj.

Nrog glucometer, kev yoo mov glycemia yog saib xyuas ntawm lub plab khoob thaum sawv ntxov, 2 teev tom qab noj mov thiab ua ntej yuav mus pw, nyob rau yav tsaus ntuj.

Cov neeg mob ntshav qab zib tau txais kev sib xyaw ua ke nrog kev npaj tshuaj insulin yuav tsum saib xyuas cov ntshav sib xyaw ua ntej txhua qhov txhaj tshuaj ntawm cov tshuaj hormones. Nws yog ib qho tseem ceeb kom taug qab qhov muaj zog ntawm kev hloov pauv hauv qhov ntsuas thoob plaws ib hnub, nrog rau kev saib xyuas cov kev ntsuas nruab nrab nyob rau lub hli - los ntawm ib tus kws kho qhov mob sab laj mus rau lub rooj sib tham tom ntej.

Cov tshuaj yog tuaj yeem muaj kev cuam tshuam zoo rau lub cev kev xav. Qhov no tuaj yeem tsim teeb meem thaum tsav tsheb, tsav kev siv lub tshuab ua haujlwm, ua haujlwm ntawm qhov siab thiab lwm yam haujlwm muaj peev xwm txaus ntshai uas xav tau kev kub siab.

Yog hais tias Glidiab qhia rau tus niam laus, nws tuaj yeem siv tsuas yog tom qab hloov tus menyuam mus rau kev pub mis.

Txog kev kho mob pob qij txha, peb cov neeg nyeem tau siv DiabeNot siv tau zoo. Pom qhov nrov ntawm cov khoom no, peb tau txiav txim siab muab nws rau koj kom txaus siab.

Cov piam thaj thiab qab zib yog qhov txaus siab tshaj plaws

Piam thaj thiab piam thaj puas zoo ib yam? Thawj qhov sib txawv hauv qhov nws yog manosaccharide, raws li muaj pov thawj los ntawm qhov muaj nyob hauv nws cov qauv tsuas yog 1 carbohydrate. Qab zib yog ib qho tsis ncaj, vim tias muaj 2 carbohydrates nyob rau hauv nws cov muaj pes tsawg leeg. Ib ntawm cov carbohydrates yog qabzib.

Cov xaim no nyob ntawm lawv qhov chaw.

Cov kua txiv, cov txiv hmab txiv ntoo, cov txiv hmab txiv ntoo - qhov chaw uas cov suab thaj thiab qab zib cov ntsiab lus tau zoo dua.

Piv nrog cov txheej txheem tsim cov piam thaj (uas yog ua rau ntawm qhov loj ntawm qhov tsawg kawg ntawm cov khoom siv raw), txhawm rau kom tau txais cov piam thaj hauv nws daim ntawv ntshiab, nws yog qhov yuav tsum tau siv cov txheej txheem thev naus laus zis zoo thiab siv zog ua haujlwm. Tau txais cov piam thaj hauv ib qho kev lag luam yog tau nrog kev pab ntawm cellulose.

Hais txog cov txiaj ntsig ntawm ob feem hauv cov khoom noj khoom haus

Cov piam thaj lossis qab zib, qhov twg yuav zoo dua? Nws tsis muaj ib lo lus teb rau lo lus nug no. Peb yuav nrog cov khoom tsis haum.

Thaum noj mov, tus neeg noj suab thaj. Nws siv tau raug lees paub tias yog kev ntxiv rau txhua yam tais diav. Cov khoom no tau dhau los nws cov chaw muaj npe 150 xyoo dhau los hauv Tebchaws Europe. Txuas ntxiv ntawm cov khoom tsis zoo ntawm lub roj teeb no.

1. Lub cev rog. Nco ntsoov tias cov piam thaj peb haus yog tsim los ua glycogen hauv lub siab. Nyob rau hauv rooj plaub thaum cov qib ntawm glycogen tsim nyob rau hauv qhov muaj cai ntau dua li qhov tsim nyog, cov piam thaj uas noj qab zib ua ib qho ntawm ntau yam tsis txaus siab uas muaj teeb meem - kev ua kom rog. Hauv qhov loj ntawm ib rooj plaub, xws li cov nyiaj tso tawm tau pom hauv plab thiab lub duav.
2. Cov laus thaum ntxov. Kev siv cov khoom txiav txim siab ntau ntawm cov khoom txhawb tau tsim kom muaj pob zeb wrinkles. Qhov kev tivthaiv no muab tso rau hauv collagen raws li kev khaws cia, uas nyob rau hauv lem txo qhov elasticity ntawm daim tawv nqaij. Kuj tseem muaj lwm qhov ntxiv los ntawm kev laus ua ntej dhau los - cov radicals tshwj xeeb yog nyiam los ntawm qab zib, uas cuam tshuam rau lub cev tsis zoo, yog li ua rau nws rhuav tshem sab hauv.
3. Kev quav. Raws li kev sim ntawm nas, nrog siv ntau zaus, ib qho kev vam khom loj tshwm. Cov ntaub ntawv no tseem cuam tshuam rau tib neeg. Siv provokes kev hloov tshwj xeeb nyob rau hauv lub hlwb uas zoo sib xws nrog yeeb los yog nicotine. Txij li tus neeg haus luam yeeb tuaj yeem tsis tuaj yeem nyob hauv ib hnub tsis muaj luam yeeb nicotine, yog li tsis muaj khoom qab zib.

Qhov xaus qhia nws tus kheej tias haus cov piam thaj ntau yog qhov txaus ntshai rau tib neeg lub cev. Nws yog qhov zoo dua rau dilute khoom noj nrog qhov ntau ntau ntawm cov piam thaj. Cov kev tshawb pom no tau txais los ntawm cov neeg ua haujlwm hauv tsev kawm qib siab hauv California.Tom qab ua cov kev sim ntau, cov kws tshawb fawb tau lees paub tias nrog kev siv ntau zaus ntawm fructose, kab mob ntawm cov kab mob hauv lub plawv pib mob, nrog rau mob ntshav qab zib.

Ib qho kev sim tau tshawb nrhiav nyob rau hauv uas cov neeg uas haus cov dej qab zib uas muaj suab thaj ntau qhia pom kev tsis hloov lub siab thiab lub siab ua rog. Cov kws kho mob tsis pom zoo kom noj cov tshuaj no. Thiab tag nrho vim hais tias txoj kev ua neej ntawm tib neeg tau hloov ntau yam, vim tias peb tsis muaj zog, vim tias muaj qhov kev tshem tawm tas li ntawm cov rog rog, uas ua rau muaj teeb meem mob plawv. Coob leej yuav tsum xav txog qhov no.

Dab tsi yuav sweeter?

Nrog rau lo lus nug ntawm qhov sib txawv ntawm cov piam thaj thiab piam thaj txheeb tawm. Tam sim no cia peb tham txog uas yog qab zib, piam thaj lossis piam thaj?

Qab zib los ntawm cov txiv ntoo yog qab zib heev hauv kev saj, thiab tseem muaj qhov ua tiav zoo. Tab sis cov piam thaj hauv siab tau ntau zaus sai dua, thiab lub zog ntau ntxiv rau. Muaj ib lub tswv yim hais tias kev ua tsis ncaj ncees muaj ntau yam khoom qab zib. Tab sis yog tias koj saib, tom qab ntawd thaum nws nkag mus rau hauv tib neeg lub qhov ncauj kab noj hniav, nws ua rau cov piam thaj thiab fructose thaum nws ntsib nrog cov qaub ncaug, tom qab ntawd nws yog qhov saj ntawm fructose uas hnov ​​hauv lub qhov ncauj. Qhov xaus yog qhov tseeb: qab zib thaum lub sij hawm hydrolysis xa tau zoo dua fructose, thiab yog li ntawd nws yog khoom qab zib ntau dua qabzib. Li no yog tias vim li cas nws thiaj li paub meej tias cov piam thaj txawv li cas ntawm cov piam thaj.

Hais lus pheej hmoo txog qhov phom sij ntawm cov piam thaj, uas tau hnov ​​hnub no los ntawm txhua lub tshuab raj, ua rau peb ntseeg tias qhov teeb meem muaj tiag.

Thiab vim tias kev hlub qab zib yog xaws hauv peb lub subconscious txij thaum yug los thiab peb tsis xav txwv nws, peb yuav tsum nrhiav lwm txoj hauv kev.

Cov piam thaj, fructose thiab sucrose yog peb hom suab thaj, uas muaj ntau yam sib xws, tab sis muaj ntau qhov sib txawv.

Lawv ib txwm muaj nyob hauv ntau cov txiv hmab txiv ntoo, zaub, khoom noj siv mis thiab nplej. Tsis tas li, ib tus neeg tau kawm cais tawm ntawm cov khoom lag luam no thiab ntxiv rau lawv ua noj ua haus ntawm lawv cov tes los txhim kho lawv cov saj.

Hauv tsab xov xwm no peb yuav tham txog yuav ua li cas cov piam thaj, fructose thiab sucrose txawv, thiab peb yuav qhia qhov tseeb ntawm lawv yog qhov muaj txiaj ntsig / tsis zoo ntxiv.

Cov kua nplaum, fructose, sucrose: sib txawv ntawm kev hais lus. Cov Ntsiab Lus

Txij li qhov pom ntawm cov tshuaj lom neeg, txhua hom piam thaj tuaj yeem faib ua monosaccharides thiab kev cais tawm.

Monosaccharides yog cov yam ntxwv zoo tshaj plaws ntawm cov piam thaj uas tsis xav tau kev zom zaub mov thiab yog nqus raws li qhov no thiab sai heev. Cov txheej txheem ntawm kev siv tshuaj txau pib twb pib hauv qhov ncauj, thiab xaus rau ntawm lub qhov quav. Cov no suav nrog qabzib thiab fructose.

Disaccharides muaj ob monosaccharides thiab rau assimilation yuav tsum tau muab faib ua lawv thaj chaw (monosaccharides) thaum lub plab zom mov. Tus sawv cev tshwj xeeb tshaj plaws ntawm kev tsis ncaj ncees yog sucrose.

Dab tsi yog sucrose?

Sucrose yog lub npe scientific rau qab zib.

Sucrose yog qhov tsis ncaj. Nws cov molecule muaj los ntawm ib qho piam thaj molecule thiab ib qho fructose Cov. I.e. raws li ib feem ntawm peb cov lus li ib txwm ua suab thaj - 50% piam thaj thiab 50% fructose 1.

Sucrose nyob rau hauv nws daim ntawv ntuj yog tam sim no nyob rau hauv ntau cov khoom ntuj (txiv hmab txiv ntoo, zaub, cereals).

Feem ntau ntawm cov lus piav qhia los ntawm qhov lus txaus siab "qab zib" hauv peb cov lus yog vim qhov tseeb tias nws muaj sucrose (khoom qab zib, mis nyuj khov, dej haus, cov hmoov qab zib).

Cov lus qab zib yog tau los ntawm cov suab thaj beets thiab kab tsib.

Sucrose qab qab tsawg dua qab zib dua li fructose tab sis qab zib tshaj qabzib 2 .

Piam thaj yog dab tsi?

Cov piam thaj yog qhov tseem ceeb ntawm lub zog rau peb lub cev. Nws yog xa los ntawm cov ntshav rau txhua lub cev ntawm lub cev rau lawv cov kev noj haus.

Qhov ntsuas ntshav li “ntshav qab zib” lossis “ntshav qab zib” qhia txog cov ntsiab lus ntawm cov piam thaj hauv nws.

Txhua lwm hom suab thaj (fructose thiab sucrose) yuav tsum muaj cov piam thaj hauv lawv cov lus, lossis yuav tsum hloov mus rau nws los siv ua lub zog.

Cov kua nplaum yog lub monosaccharide, i.e. Nws tsis tas yuav ua kom kev zom zaub mov thiab yog nqus tau sai heev.

Hauv cov zaub mov ntuj, feem ntau nws yog ib feem ntawm cov khoom noj (carbohydrates) - polysaccharides (hmoov txhuv nplej siab) thiab muaj kev cuam tshuam (sucrose lossis lactose (muab cov qab zib rau mis)).

Ntawm tag nrho peb hom piam thaj - qabzib, fructose, sucrose - Cov piam thaj yog qhov qab zib tsawg tshaj plaws hauv kev saj 2 .

Dab tsi yog fructose?

Fructose lossis "txiv hmab txiv ntoo qab zib" kuj yog ib qho monosaccharide, zoo li muaj piam thaj, i.e. nqus tau sai sai.

Lub qab qab zib ntawm cov txiv hmab txiv ntoo feem ntau thiab zib ntab yog vim lawv cov ntsiab lus fructose.

Nyob rau hauv daim ntawv ntawm sweetener, fructose yog tau los ntawm tib lub suab thaj beet, kab tsib thiab pob kws.

Muab piv rau sucrose thiab qabzib, fructose muaj lub qab zib tshaj plaws 2 .

Fructose tau dhau los tshwj xeeb tshaj yog cov neeg mob ntshav qab zib niaj hnub no, vim tias txhua yam piam thaj nws muaj kev cuam tshuam tsawg tshaj plaws rau cov ntshav qab zib 2. Ntxiv mus, thaum nws siv ua ke nrog cov piam thaj, fructose nce qhov feem ntawm cov piam thaj khaws cia los ntawm lub siab, uas ua rau nws txo qis hauv nws qib hauv cov ntshav 6.

Sucrose, qabzib, fructose yog peb hom suab thaj uas txawv hauv lub sijhawm sib tov (yam tsawg kawg nkaus rau qabzib thiab fructose), qab zib (ntau kawg rau fructose) thiab cuam tshuam rau cov ntshav qab zib (yam tsawg kawg rau fructose)

Cov piam thaj yuav nqus li cas

Thaum cov piam thaj nkag mus rau hauv cov ntshav, nws pab txhawb txoj kev tso tawm ntawm cov kua dej, kev thauj mus los uas nws cov hauj lwm xa nws mus rau hauv cov ntshav.

Nyob ntawd, nws yog qhov tshuaj lom tam sim ntawd "rau hauv lub cub tawg" rau kev hloov mus rau lub zog, lossis khaws cia ua glycogen hauv cov leeg thiab mob siab rau kev siv txuas ntxiv 3.

Yog tias theem ntawm cov piam thaj hauv cov ntshav tsawg thiab carbohydrates tsis muab los ntawm cov zaub mov, ces lub cev muaj peev xwm tsim nws los ntawm cov rog thiab cov protein, tsis yog los ntawm cov uas pom hauv zaub mov, tab sis kuj los ntawm cov uas khaws cia hauv lub cev 4.

Nov qhia txog tus mob mob nqaij hlav catabolism lossis nqaij leeg paub hauv kev tsim kho lub cev kom zoo rog hlawv cev hos kev txwv cov khoom noj tsis muaj calorie ntau.

Tuam TSAWB RESEARCH

Cov txiaj ntsig ntawm kev kawm ntau tshaj plaws ntawm kev sib raug zoo ntawm kev noj haus thiab kev noj qab haus huv

Cov txiaj ntsig ntawm kev kawm ntau tshaj plaws ntawm kev sib raug zoo ntawm kev noj haus thiab kev noj qab haus huv, kev noj nyob tsiaj muaj protein thiab .. mob cancer

"Phau ntawv tus naj npawb 1 ntawm cov zaubmov noj zaub mov, uas kuv qhia txhua tus neeg nyeem, tshwj xeeb tshaj yog cov neeg ncaws pob. Kaum xyoo ntawm kev tshawb fawb los ntawm cov kws tshawb fawb muaj koob npe hauv ntiaj teb qhia pom qhov tseeb txog cov kev sib raug zoo ntawm kev noj tsiaj muaj protein thiab .. mob cancer "

Andrey Kristov,
qhov chaw tsim

Qhov ntxim nyiam ntawm cov leeg nqaij catabolism muaj ntau heev thaum noj zaub mov muaj txiaj ntsig: lub zog los ntawm carbohydrates thiab cov rog, thiab cov leeg nqaij muaj peev xwm raug rhuav tshem kom paub tseeb tias kev ua haujlwm ntawm cov kabmob tseem ceeb (lub hlwb, piv txwv) 4.

Cov piam thaj yog qhov pib ua lub zog rau txhua lub cev hauv lub cev. Thaum nws siv, theem ntawm cov tshuaj hormones insulin hauv cov ntshav nce siab, uas thauj cov piam thaj hauv lub hlwb, suav nrog cov leeg nqaij, rau kev hloov mus ua lub zog. Yog tias muaj cov piam thaj ntau dhau, ib feem ntawm nws khaws cia ua glycogen, thiab ib feem tuaj yeem hloov mus rau rog

Npaum li cas yog fructose nqus tau?

Zoo li qabzib, fructose yog nqus sai heev.

Tsis zoo li piam thaj, tom qab nqus ntawm fructose ntshav qab zib nce siab zuj zus thiab tsis ua rau muaj kev cuam tshuam rau hauv insulin theem 5.

Rau cov neeg mob ntshav qab zib uas muaj qhov ua tsis taus tshuaj insulin, qhov no yog qhov zoo.

Tab sis fructose muaj ib qho tseem ceeb pom qhov txawv.

Txhawm rau kom lub cev muaj peev xwm siv fructose rau lub zog, nws yuav tsum hloov mus rau cov piam thaj. Qhov kev hloov siab no tshwm sim hauv lub siab.

Nws ntseeg tias daim siab yog tsis muaj peev xwm ua cov txheej txheem ntau ntawm fructose, thiab, yog tias muaj ntau dhau ntawm nws hauv kev noj haus, qhov dhau heev yog hloov pauv mus rau triglycerides 6, uas tau paub txog kev tsis zoo rau kev noj qab haus huv, nce qhov kev pheej hmoo ntawm kev rog, kev ua haujlwm ua lub siab rog, thiab lwm yam. 9. 9.

Qhov kev xav no feem ntau siv los ua kev sib cav nyob hauv kev sib cav "dab tsi yog qhov muaj kev phom sij ntau dua: qab zib (sucrose) lossis fructose?".

Txawm li cas los xij, qee qhov kev tshawb fawb tawm tswv yim qhia tias cov cuab yeej los nce qib ntawm triglycerides hauv cov ntshav muaj qhov sib luag ntawm cov tib neeg ntawm fructose, thiab sucrose, thiab qabzib, thiab tsuas yog tias lawv tau noj ntau dhau (hauv kev xav tau ntawm cov calories txhua hnub), thiab tsis yog thaum twg nrog lawv cov kev pab, ib feem ntawm cov calories tau hloov pauv, hauv cov cai tso cai ntawm 1.

Fructose, tsis zoo li qabzib, tsis ntau tshaj qib qib ntawm insulin nyob rau hauv cov ntshav thiab ua nws maj mam. Qhov no yog qhov zoo rau cov neeg mob ntshav qab zib. Cov qib triglycerides ntau hauv cov ntshav thiab nplooj siab, uas feem ntau sib ceg muaj kev phom sij ntau dua li fructose dua li cov piam thaj, tsis muaj cov pov thawj tseeb.

Yuav ua li cas sucrose yog nqus tau

Sucrose txawv ntawm fructose thiab qabzib rau hauv qhov ntawd nws yog qhov tsis ncaj ncees, i.e. rau assimilation nws yuav tsum tau tawg cia rau hauv cov piam thaj thiab fructose Cov. Tus txheej txheem no ib nrab pib hauv lub qhov ncauj kab noj hniav, txuas ntxiv hauv plab thiab xaus rau hauv txoj hnyuv me.

Txawm li cas los xij, kev sib xyaw ntawm ob hom piam thaj no ua ib qho kev ntxim nyiam ntxiv: nyob rau hauv lub xub ntiag ntawm cov piam thaj, ntau fructose yog nqus thiab insulin qib nce ntau dua , uas txhais tau tias muaj peev xwm nce siab ntxiv rau qhov muaj peev xwm ua kom muaj roj ntau dua 6.

Fructose nws tus kheej hauv cov neeg feem ntau tsis zoo thiab, thaum muaj qee yam, lub cev tsis lees nws (fructose intolerance). Txawm li cas los xij, thaum cov piam thaj tau noj nrog fructose, qhov ntau dua nws yuav nqus tau.

Qhov no txhais tau tias thaum koj noj fructose thiab qabzib (uas yog rau cov piam thaj), cov kev tsis zoo yuav muaj zog dua li thaum lawv noj nyias.

Nyob rau sab hnub poob, cov kws kho mob niaj hnub no thiab cov kws tshawb fawb tau tshwj xeeb yog qhov tshwj xeeb ntawm kev siv cov lus "pob kws ua kua" nyob rau hauv cov zaub mov, uas yog qhov sib xyaw ua ke ntawm ntau hom suab thaj. Ntau cov ntaub ntawv tshawb fawb qhia tau tias nws muaj kev phom sij rau kev noj qab haus huv.

Sucrose (los yog qab zib) sib txawv ntawm cov piam thaj thiab fructose hauv qhov ntawd nws yog kev sib txuam. Cov kev phom sij rau kev noj qab haus huv ntawm kev sib koom ua ke (tshwj xeeb tshaj yog hais txog kev rog) tuaj yeem hnyav dua li nws lub cev sib xyaw

Yog li dab tsi yog qhov zoo dua (tsis muaj teeb meem): sucrose (qab zib)? fructose? lossis piam thaj?

Rau cov neeg muaj kev noj qab haus huv, tsis muaj qhov laj thawj tsis ntshai rau cov suab thaj uas twb tau pom hauv cov khoom lag luam: ntuj yog qhov muaj txiaj ntsig zoo thiab tsim cov khoom noj hauv txoj kev zoo li ntawd, kev noj zaub mov rau lawv nkaus xwb, nws yog qhov nyuaj heev rau kev phom sij rau koj tus kheej.

Cov khoom xyaw hauv lawv yog qhov sib npaug, lawv tau saturated nrog fiber ntau thiab dej thiab nws yuav luag tsis yooj yim sua.

Qhov ua mob rau cov suab thaj (ob qho tib si cov lus qab zib thiab fructose) uas txhua tus neeg sib tham txog hnub no yog ib qho txiaj ntsig ntawm lawv siv nyob rau hauv ntau dhau lawm .

Raws li qee qhov kev txheeb cais, qhov nruab nrab Westerner noj txog 82 g suab thaj hauv ib hnub (tsis suav nrog uas twb pom hauv cov khoom lag luam ntuj). Qhov no yog kwv yees li 16% ntawm tag nrho cov calories ntau ntawm cov zaub mov - tseem ceeb tshaj qhov tau hais kom ua.

Ua kom nws pom tseeb dua, peb txhais cov lus ntawm cov khoom: 330 ml ntawm Coca-Cola muaj txog 30 g suab thaj 11. Qhov no, nyob rau hauv hauv paus ntsiab lus, yog txhua yam uas tso cai ...

Nws tseem yog ib qho tseem ceeb rau hauv lub siab tias cov piam thaj ntxiv tsis tsuas yog ua rau cov khoom noj qab zib (ice cream, khoom qab zib, chocolate). Nws tuaj yeem pom hauv "savory qab qab": cov kua ntses, ketchups, mayonnaise, khob cij thiab hnyuv ntxwm.

Rau lawv, noj zaub mov fructose yog qhov tsis tshua muaj suab thaj. los sis cov piam thaj ntshiab, txij li nws muaj qis glycemic Performance index thiab tsis ua rau kom cov ntshav qab zib nce siab.

Yog li cov lus qhia dav dav yog qhov no:

• kom tsawg tshaj plaws, thiab nws yog qhov zoo dua rau tshem tawm los ntawm kev noj zaub mov hauv feem ntau txhua yam piam thaj (qab zib, fructose) thiab cov khoom lag luam tsim los ntawm lawv hauv cov khoom loj,
• tsis txhob siv cov khoom qab zib, txij li ib qho dhau ntawm ib qho ntawm nws yog fraught nrog kev mob nkeeg,
• tsim koj cov khoom noj kom yuag tsuas yog rau tag nrho cov khoom noj organic thiab tsis txhob ntshai cov suab thaj hauv lawv cov muaj pes tsawg leeg: txhua yam yog "muaj cov neeg ua haujlwm" hauv cov khoom muaj cai nyob rau ntawd.

Txhua hom suab thaj (ob lub rooj qab zib thiab fructose) muaj kev phom sij rau kev noj qab haus huv thaum noj ntau. Hauv lawv daim foos, ua ib feem ntawm cov khoom ntuj, lawv tsis muaj teeb meem. Rau cov mob ntshav qab zib, fructose yog qhov tsis tshua muaj teeb meem dua li sucrose.

Pharmacodynamics thiab pharmacokinetics

Gliclazide yog qhov ncauj tshuaj hypoglycemic hais txog tshuaj ntsuab rau lub zog sulfonylureas 2nd tiam. Qhov kev txiav txim ntawm cov tshuaj yog tswj rau kev ua kom muaj β-hlwb hauv, ua khoom, nce qhov chaw muaj qhov tsis haum ntawm cov ntaub so ntswg feem ntau rau nws, ntxiv dag zog piam thaj insulin secretion teebmeem thiab txhawb kev ua haujlwm ntawm intracellular glycogen synthetase hauv cov leeg ua ke. Cov tshuaj txo cov sijhawm hauv lub sijhawm txij li lub sijhawm ua zaub mov mus txog thaum pib ntau lawm tshuaj insulintxo qis postprandial qabzib, thiab tseem rov kho qhov ntxov (thawj) ncov cov tshuaj insulin zais cia (tsis zoo li lwm yam tshuaj sulfonylureasfeem ntau ua haujlwm nyob rau theem ob).

Ntxiv nrog rau kev tswj kev ua kom muaj roj metabolism gliclazide txhim kho microcirculationlos ntawm kev txo qis platelet thiab, normalization ntawm vascular permeability, kho tshiab ntawm cov txheej txheem physiological parietal fibrinolysis.

Glidiab kev kho mob txo cov kev nkag siab ntawm cov hlab ntshav mus rau kis, tiv thaiv kev tsim thiab. Nws inhibits qhov kev vam meej ntawm tsis-loj hlob (keeb kwm yav dhau). Nrog rau kev kho mob ntev, muaj qhov txo qis pom, txhim kho ntawm cov keeb kwm yav dhau losuas mob ntshav qab zib nephropathy.

Noj tshuaj, vim nws cov nyhuv rau theem thaum ntxov insulin zais cia, tsis yog nrog los ntawm kev nce phaus thiab tseem nyiam nws txo qis hauv cov neeg mob rog, yog tias tsim nyog.

Qhov ncauj tswj hwm gliclazide ua rau nws txoj kev nqus yuav luag tiav hauv cov hnyuv. TCmax hauv ntshiab yog 4 teev (rau MV ntsiav tshuaj - 6-12 teev). Kev khi rau cov ntshav plasma protein yog nyob rau theem ntawm 90-95%. Kev hloov pauv khoom noj muaj tshwm sim hauv lub siab nrog kev tso tawm ntawm cov khoom tsis tawm. T1 / 2 yog 8-11 teev (rau MV cov ntsiav tshuaj - 16 teev). Kev zam nyob rau hauv daim ntawv yog nqa tawm tsuas yog los ntawm lub raum (kwv yees li 70%), nrog rau cov hnyuv (12%). Li ntawm 1% gliclazide tawm tsis hloov pauv hauv zis.

Kev siv cov Glidiab yog contraindicated nyob rau hauv:

• mob ketoacidosis,
• Hom 1,
• uas precom /
• hnyav/ ,
• leukopenia,
• mob mob, nrog qhov xav tau siv tshuaj insulinsuav nrog kev raug mob, phais kev ua haujlwmdav hlawv,
• paresis ntawm lub plab,
• hnyuv tawm tsam,
• pathologies nrog los ntawm malabsorption cov khoom noj thiab cov duab ntshav qog (suav nrog cov mob sib kis)
• tus kheej kev tiv thaiv tsis haum rau gliclazide lossis lwm yam tshuaj
• thaum yau.

Sab sij huam

Qhov feem ntau muaj thiab mob tshwm sim ntawm Glidiab yog ntshav qog, feem ntau tshwm sim los ntawm kev ua txhaum ntawm kev haus tshuaj thiab tsis txaus kev kho kev noj hausCov. Cov tsos mob ntawm qhov kev cuam tshuam no yog ntau haiv neeg thiab tuaj yeem tshwm sim nws tus kheej :, los ntawm kev xav ntawm kev tshaib plab, zoo nkaus li nkees, tsis muaj kev cia siab, ntxhov siab, txhoj puab heevtxob taus xeevqeeb cov tshuaj tiv thaiv, tsis muaj peev xwm mloog zoo, pom kev pomtsis paub pab aphasiapiav thoob hlo delirium, kev plam tus kheej, spasmstsis nco qab hypersomnia, pa ua pa, bradycardia.

Qhov thib ob tseem ceeb tshaj plaws corking los ntawm Glidiab txoj kev kho yog suav tias yog qhov tsis zoo tshwm sim los ntawm kev mob plab, uas tau hais tawm (xeev siab, hnyav ntawm epigastrium thiab), kev ua txhaum hepatic muaj nuj nqi (nce hauv kev ua sidaim siab ua kua transaminase, cholestatic mob daj ntseg), (tus noj tshuaj ntsiav nrog zaub mov, mob hnyav kev tsis nco qab txo qis).

Qee zaum pom tsim leukopenia, thrombocytopenia thiab anemia.

Glidiab, cov lus qhia rau kev siv

Qhov kev xaiv ntawm cov tshuaj ntau npaum li cas ntawm cov tshuaj Glidiab yog nqa tawm ib leeg zuj zus raws li kev kuaj mob NIDDM thiab qib txhauv, uas yog ntsuas ntawm lub plab khoob, tas li tom qab 2 teev tom qab noj mov.

Thaum pib, kom noj tshuaj txhua hnub ntawm 1 Glidiab 80 mg ntsiav tshuaj lossis koob thib 1 Glidiab MV 30 mg ntsiav tshuaj tau pom zoo. Qhov nruab nrab txhua hnub muab tshuaj yog 160 mg thiab 60 mg, thiab qhov siab tshaj plaws yog 320 mg thiab 120 mg, feem, rau cov tshuaj thiab MV ntsiav tshuaj. Conventional Glidiab 80 mg ntsiav tshuaj yog noj 30-60 feeb ua ntej noj mov ob zaug hauv 24 teev (thaum sawv ntxov thiab yav tsaus ntuj). Ntsiav tshuaj MV 30 mg yog qhia tias yuav tsum noj ib zaug sawv ntxov thaum noj tshais. Kev txhaj tshuaj ntau ntxiv tuaj yeem nqa nrog ib ncua sijhawm tsawg kawg 14 hnub.

Cov laus thiab cov neeg mob nrog raum pathologies (nrog CC 15-80 ml / min) tsis xav tau hloov qhov tshuaj.

Kev sib txuam

Kev txo qis hauv hypoglycemic zoo ntawm Glidiab yog pom nyob rau hauv cov ntaub ntawv ntawm nws thaum uas tig mus siv nrog glucocorticoids, barbituratessympathomimetics (Terbutaline, , Ritodrin,), calcium kws thaiv kev phom sij, ntsev ntsev, thiazide diureticscarbonic anhydrase inhibitors (), Triamteren, , , Asparaginase, , Diazoxide, , , , Glucagon., thiab cov thyroid caj pas (suav nrog).

Kev sib koom tes ntawm Glidiab thiab mob glycosides nce txoj kev pheej hmoo ntawm kev tsim ventricular extrasystole.

Qhov cuam tshuam ntawm β-blockers ,,, Guanethidine tej zaum yuav ua rau pom mob dab tsi ntshav qog.

Cia rau cov neeg mob

Qhov cia siab ntau tshaj plaws ntawm cov ntsiav tshuaj thiab cov ntsiav tshuaj ntawm MV Glidiab yog 25 ° C.

Cov tib neeg uas muaj tus mob ntshav qab zib hom 2 tsis yog ib txwm muaj peev xwm tswj cov ntshav qabzib hauv lub cev los ntawm kev noj haus thiab kev tawm dag zog. Yog li, qee tus neeg mob ntshav qab zib yuav tsum tau siv cov tshuaj hypoglycemic, tshwj xeeb hauv Glidiab.

Cov tshuaj no yuav pab kom tswj tau cov ntshav nyob hauv ntshav ntau npaum li cas, thiab nce cov txiaj ntsig kev noj zaub mov zoo yog tias tus mob ntshav qab zib ua mob rog. Tsis tas li ntawd, thaum siv Glidiab MV 30, lub siab ntawm cov kua dej tso kua mis rov qab.

Kuv tuaj yeem yuav cov tshuaj Glidiab ntau npaum li cas? Hauv cov tsev muag tshuaj, tus nqi ntawm cov tshuaj yog 120-200 rubles. Tus nqi yuav nce raws tus nqi ntawm cov khoom xyaw nquag hauv cov ntsiav tshuaj. Glidiab MB 30 mg thiab 80 mg yog lag luam muag.

Tus txheej txheem ntawm kev nqis tes ua thiab kev taw qhia rau kev siv

Glidiab MV yog ib tus neeg sawv cev hypoglycemic rau cov pab pawg ntawm sulfonylurea derivatives ntawm 2 tiam. Cov tshuaj yog muaj gliclazide thiab tshem tawm. Glyclazide hauv ib ntsiav tshuaj muaj 80 mg lossis 30 mg.

Cov tshuaj tiv thaiv tsis ua hauj lwm li cas? Glyclazide raws li qhov nqus tau stimulates cov leeg glycogen synthetase kev ua ub no thiab cov kua dej tso pa tawm. Tsis tas li, cov tshuaj no potentiates insulin secretory nyhuv ntawm cov piam thaj, thiab ua rau muaj kev nce siab hauv qhov rhiab ntawm cov ntaub so ntswg mus rau insulin.

Ntxiv mus, gliclazide pab txo cov kis nruab nrab ntawm kev noj zaub mov thiab pib ntawm lub cev ua haujlwm ntawm cov kua dej insulin. Yog tias koj saib cov lus qhia rau kev siv rau Glidiab, koj tuaj yeem pom tias thaum koj siv cov ntsiav tshuaj, lub siab ntawm hyperglycemia poob qis, thiab thaum ntxov ntawm cov tshuaj insulin tso rov qab.

Tag nrho cov yam cuam tshuam ncaj qha cuam tshuam rau cov metabolism hauv cov metabolism thiab microcirculation. Yog tias koj ntseeg tias cov lus qhia, tom qab ntawd Glidiab MV pab txo qis rau kev txhawm thiab txhawm rau platelets, thiab tib lub sijhawm ua rau vascular permeability.Yooj yim muab, nrog kev siv cov ntsiav tshuaj, qhov ntxim nyiam ntawm kev kho mob ntawm microthrombosis thiab atherosclerosis yog txo qis.

Cov kev tshawb fawb kuj tau pom tias tus neeg sawv cev hypoglycemic pab ua kom qeeb ntawm kev txhim kho cov teeb meem xws li mob ntshav qab zib ntawm lub cev tsis nyob ntawm theem. Ntxiv mus, siv Glidiab MV ntsiav tshuaj tuaj yeem cuam tshuam rau kev ua haujlwm ntawm kev noj zaub mov noj rau cov neeg mob nyhav.

Kuv xav nco ntsoov tias cov tshuaj metabolites ntawm cov tshuaj tau nthuav tawm ua ke nrog cov zis hauv ib daim ntawv hloov pauv, thiab ua ke nrog quav nyob rau hauv daim ntawv ntawm metabolites.

Cov lus qhia rau kev siv tshuaj

Nyob rau hauv rooj plaub dab tsi yog nws raug nquahu kom siv Glidiab 80 ntsiav tshuaj? Cov lus qhia tau hais tias nws raug nquahu kom siv cov tshuaj hauv kev kho mob hom 2 ntshav qab zib mellitus, yog tias kev noj zaub mov noj thiab kev tawm dag zog tsis pab tswj cov ntshav qabzib.

Ua nrog rau lwm cov tshuaj, Glidiab MB tsis tshua muaj neeg siv. Tab sis nws yuav tsum nco ntsoov tias qhov ua rau lub ntsej muag hypoglycemic ntawm cov tshuaj tuaj yeem nce ntxiv yog tias, nrog rau kev siv tshuaj kho mob, kev noj haus thiab kev ua si kis las yog qhov sib npaug.

Yuav noj li cas? Qhov hno koob yog 80 mg. Ntxiv mus, qhov ntau zaus ntawm kev siv yog 2 zaug hauv ib hnub - thaum sawv ntxov thiab yav tsaus ntuj. Nws raug nquahu kom noj cov ntsiav tshuaj 30-60 feeb ua ntej noj mov.

Yog tias qhov koob tshuaj tsawg kawg nkaus ntawm 80 mg tsis muaj ib qho kev tiv thaiv hypoglycemic, ces qhov muab tshuaj yog maj mam nce. Feem ntau, hauv hom 2 mob ntshav qab zib, koob ntawm 160 mg yog qhov zoo tshaj. Qhov siab tshaj plaws tau ntau npaum li cas ntawm cov tshuaj yog 320 mg.

Tab sis peb yuav tsum nco ntsoov tias nrog rau cov koob tshuaj ntau ntxiv, qhov ntxim nyiam ntawm kev muaj ntshav qab zib thiab lwm yam kev mob tshwm sim ntau dua.

Kev sib cuam tshuam txog yeeb tshuaj thiab Tshuaj Tiv Thaiv

Nws yuav tsum nco ntsoov hais tias ib tug xov tooj ntawm cov tshuaj muaj peev xwm nce hypoglycemic nyhuv ntawm yeeb tshuaj Glidiab MB. Yog li, cov lus qhia tau sau tseg tias cov tshuaj yuav tsum yog ua tib zoo ua ke nrog histamine H2-receptor blockers, tshuaj tsis-steroidal anti-inflammatory tshuaj, antifungal agents, ACE inhibitors.

Cov tshuaj tiv thaiv tuberculosis, beta-adrenoblockers, nphav phav phav hom anticoagulants, anabolic steroids, MAO inhibitors, salicylates thiab lwm tus kuj tseem tuaj yeem ua rau muaj kev tiv thaiv hypoglycemic.

Yog vim li cas, ua ntej siv cov ntsiav tshuaj Glidiab, koj yuav tsum ua tib zoo kawm cov lus qhia thiab sab laj tus kws kho mob.

Ntawm cov contraindications kom siv cov ntsiav tshuaj yuav qhia tau:

1. Ntshav Qab Zib Hom 1 yog insulin-vam khom.
2. Ntshav qab zib ketoacidosis.
3. Xav sim lossis tsis nco qab. Ntxiv mus, ib qho nruj contraindication yog hyperosmolar coma.
4. Leukopenia
5. Lub sijhawm cev xeeb tub.
6. Lub sijhawm lactation.
7. Mob rau hepatic thiab lub raum tsis ua haujlwm.
8. Cov xwm txheej uas nrog ua ke los ntawm kev ua txhaum ntawm cov txheej txheem ntawm kev nqus ntawm cov khoom noj, thiab kev txhim kho ntawm lub qog ntshav qab zib. Cov mob no suav nrog kev cuam tshuam ntawm cov hnyuv, paresis ntawm lub plab thiab cov kis kab mob.
9. Ua xua rau cov khoom xyaw ntawm cov ntsiav tshuaj.
10. Tej yam mob uas yuav tsum tau siv tshuaj insulin. Cov mob no suav nrog hlawv, raug mob, lossis phais mob.
11. Kev quav cawv
12. Lub siab ntsws Febrile.

Tsis tas li, cov tshuaj yuav tsum tau siv nrog ceev faj hauv cov neeg kev txom nyem los ntawm cov thyroid tsis ua hauj lwm.

Kev txheeb xyuas thiab cov kev mob tshwm sim ntawm Glidiab

Qhov kev ntsuam xyuas txog Glidiab yog dab tsi? Tus mob ntshav qab zib tau teb zoo rau cov tshuaj. Coob tus neeg tau txais kev txaus siab los ntawm tus nqi pheej yig ntawm cov tshuaj, thiab tus nqi tsim nyog siab.

Ntxiv mus, Gladiab, raws li cov neeg mob ntshav qab zib, yog qhov zoo vim tias nws tsis tshua muaj kev phiv los ntawm kev siv tshuaj tsawg. Lwm qhov kev ntaus nqi ntawm cov tshuaj rau cov tib neeg yog qhov tseeb tias nws nce lub txiaj ntsig ntawm kev kho kev noj haus.

Cov kev phiv dab tsi tuaj yeem ua rau cov tshuaj hypoglycemic ua rau? Raws li cov lus qhia, cov tshuaj tuaj yeem ua rau:

• Kev ua txhaum ntawm endocrine system.Lawv tshwm sim hauv daim foos. Tab sis nws yuav tsum raug sau tseg tias qhov kev lees paub no tsuas yog tshwm sim nrog kev xaiv tsis zoo ntawm qhov tshuaj.
• Kev tsis haum xeeb, nkees nkees, tawm tsam kev tawm tsam, ua kom lub cev ntaj ntsug, mob taub hau, kiv taub hau, nce zog.
• Tsawg dua pom pom tseeb tseeb.
• Cov Niampaus.
• Lub Neej Bradycardia
• Ua pa.
• Ncuav Qab Zib.
• Thrombocytopenia, ua haujlwm tsis txaus, leukopenia.
• Kev ua xua tsis haum.
• Digestive system malfunction. Ib tus neeg yuav mob raws plab, qhov kev xav nyob rau hauv thaj chaw epigastric, xeev siab, tsis nco qab, mob cholestatic daj ntseg, nce kev ua haujlwm ntawm hepatic transaminases.

Feem ntau, cov kev mob tshwm sim los daws lawv tus kheej tom qab tsis haus yeeb tshuaj thiab tau txais kev kho mob raws li qhov tsim nyog.

Pharmacological ua ntawm glidiab mv

Tus neeg sawv cev ntawm tus mob ntshav qab zib ntau ntau, yog sulfonylurea derivative ntawm lub cim thib ob. Pab tsim lub cev tawm ntawm cov insulin los ntawm cov leeg hlwb. Tsub qhov rhiab heev ntawm peripheral cov ntaub so ntswg rau insulin. Thaj, nws txhawb qhov kev ua si ntawm intracellular enzymes (hauv tshwj xeeb, nqaij glycogen synthetase). Txo lub sijhawm ua ntu zus los ntawm lub sijhawm noj mov kom pib lub insulin secretion. Rov kho lub sijhawm thaum ntxov ntawm insulin secretion, txo qis ncov tom qab ntawm hyperglycemia.

Glyclazide txo cov platelet adhesion thiab kev sib sau ua ke, qeeb rau kev txhim kho ntawm parietal thrombus, thiab nce vascular fibrinolytic kev ua si. Normalizes vascular permeability. Nws muaj cov tshuaj tiv thaiv antiatherogenic: nws txo qis cov kev sib txuam ntawm cov roj (cholesterol) thiab cov roj (cholesterol) / LDL hauv cov ntshav, nce qhov siab ntawm cov roj (cholesterol) / HDL, thiab tseem txo cov naj npawb dawb. Tiv thaiv kev txhim kho ntawm microthrombosis thiab atherosclerosis. Txhim kho microcirculation. Txo kom vascular rhiab heev rau adrenaline.

Nrog rau cov ntshav qab zib nephropathy nrog kev siv lub sijhawm ntev ntawm gliclazide, qhov tseem ceeb txo qis rau cov proteinuria tau sau tseg.

Xaus

Sucrose, qabzib thiab fructose txhua tus muaj qab zib, tab sis fructose yog qhov qab zib tshaj plaws.

Tag nrho peb hom suab thaj no tau siv hauv lub cev rau lub zog: cov piam thaj yog qhov pib ntawm lub zog, fructose yog hloov pauv rau cov piam thaj hauv lub siab, thiab sucrose tau tawg ua ob qho.

Tag nrho peb hom suab thaj - qabzib, frutose, thiab sucrose - muaj nyob rau ntau yam zaubmov qab ntuj. Tsis muaj ib qho txhaum hauv lawv qhov kev siv.

Qhov mob rau kev noj qab haus huv yog lawv dhau heev lawm. Txawm hais tias qhov tseeb tau sim ua feem ntau los nrhiav qhov "muaj piam thaj ntau dua", kev tshawb fawb txog kev tshawb fawb tsis tau qhia meej tias nws muaj tshwm sim: cov kws tshawb fawb soj ntsuam kev tsis zoo thaum siv ib qho twg ntawm kev siv ntau dhau.

Nws yog qhov zoo tshaj plaws kom tsis txhob muaj kev siv cov khoom qab zib, thiab txaus siab saj ntawm cov khoom ntuj muaj nrog lawv (txiv hmab txiv ntoo, zaub).

Cov khoom ntawm sucrose yuav tsum raug txiav txim siab hauv cov ntawv ntawm physics thiab chemistry. Cov xaim yog qhov tsis sib xws, feem ntau ntawm txhua yam nws yog nyob rau hauv kab tsib thiab beets.

Thaum nws nkag mus rau txoj hnyuv hauv plab, tus qauv ntawm sucrose tau tawg rau hauv cov carbohydrates yooj yim - fructose thiab qabzib. Nws yog cov khoom siv dag zog, tsis muaj qhov ua haujlwm li cas ntawm lub cev tsis tau.

Cov cuab yeej twg yog tus yam ntxwv ntawm yam khoom twg, thiab yam ua nws ua rau lub cev, raug nthuav tawm hauv cov khoom no.

Kev sib xyaw thiab cov khoom ntawm lub zog

Sucrose (lwm lub npe - kab tsib suab thaj lossis sucrose) yog ib qho tsis muaj txiaj ntsig los ntawm cov pab pawg ntawm oligosaccharides uas muaj 2-10 monosaccharide seem. Nws muaj ob lub ntsiab - alpha qabzib thiab beta fructose. Nws cov khoom siv tshuaj lom neeg yog C 12 H 22 O 11.

Cov tshuaj hauv nws daim ntawv dawb huv yog sawv cev los ntawm pob tshab monoclinic muaju. Thaum lub melted loj solidifies, caramel yog tsim, i.e. amorphous daim ntawv tsis muaj xim.Cane suab thaj yog soluble heev nyob rau hauv dej (H 2 O) thiab ethanol (C 2 H 5 OH), sparingly soluble hauv methanol (CH 3 OH) thiab yuav luag tsis muaj qhov tsis haum hauv diethyl ether ((C 2 H 5) 2 O). Cov tshuaj yeeb yaj kiab tuaj yeem yaj ntawm qhov kub ntawm 186 ℃.

Sucrose tsis yog aldehyde, tab sis suav hais tias yog kev txiav txim siab tseem ceeb tshaj plaws. Yog hais tias sucrose yog rhuab nrog kev daws teeb meem ntawm ammonia Ag 2 O, ces qhov tsim ntawm "tsom iav nyiaj" yuav tsis tshwm sim. Ua kom sov cov khoom siv nrog Cu (OH) 2 yuav tsis ua rau kev tsim cov tooj liab oxide. Yog tias koj rhais cov dej ntawm sucrose ua ke nrog hydrogen chloride (HCl) los yog sulfuric acid (H 2 SO 4), thiab tom qab ntawd ua kom nruab nrab nrog alkali thiab muab nws kub nrog Cu (OH) 2, tom qab ntawd ib qho xim liab tau txais thaum kawg.

Hauv qab dej, qabzib thiab fructose yog tsim. Ntawm cov sucrose isomers muaj tib lub mis, lactose thiab maltose yog qhov sib cais.

Cov khoom lag luam muaj dab tsi nyob hauv?

Nyob rau hauv cov xwm, qhov tsis pom zoo no kuj muaj ntau. Sucrose muaj nyob hauv cov txiv ntoo, txiv hmab txiv ntoo, thiab cov txiv ntoo.

Hauv cov ntau, nws muaj nyob hauv kab tsib thiab qab zib beets. Kab tsib muaj nyob hauv thaj chaw tropics thiab South America. Hauv nws cov qia yog 18-21% suab thaj.

Nws yuav tsum raug sau tseg tias nws yog los ntawm pas nrig tias 65% ntawm lub ntiaj teb cov khoom qab zib yog tau. Cov coj lub teb chaws rau kev tsim cov khoom lag luam yog Is Nrias teb, Brazil, Suav, Thaib, Mexico.

Beetroot muaj kwv yees li 20% sucrose thiab yog ob xyoos ntoo. Cov hauv paus qoob loo hauv Lavxias lub tebchaws tau pib loj hlob, pib hauv xyoo XIX. Tam sim no, Russia tau loj hlob txaus qab zib beets los pub rau nws tus kheej thiab xa cov beet qab zib rau txawv teb chaws.

Ib tug neeg tsis pom txhua qhov uas nyob hauv nws txoj kev noj haus li niaj zaus muaj sucrose. Nws muaj nyob hauv cov zaub mov no:

• hnub tim
• hoob pob
• prunes
• gingerbread khaub noom
• marmalade
• raisins
• irge
• kua marshmallow,
• medlar
• zib muv
• kua txiv kua txiv
• qab zib straws
• qhuav figs
• birch kua ntoo
• lub dib pag
• persimmon

Tsis tas li ntawd, muaj ntau npaum li cas ntawm sucrose nyob hauv carrots.

Lub txiaj ntsig ntawm sucrose rau tib neeg

Sai li cov piam thaj nyob rau hauv cov zom zaub mov, nws zom rau hauv cov carbohydrates yooj yim. Tom qab ntawd lawv tau nqa los ntawm cov roj ntsha mus rau txhua cov qauv ntawm cev.

Ntawm qhov tseem ceeb hauv kev tawg ntawm sucrose yog qabzib, vim nws yog qhov khoom tseem ceeb rau lub zog rau txhua yam muaj sia. Ua tsaug rau cov tshuaj no, 80% ntawm cov nqi zog tau them nyiaj.

Yog li, qhov tseem ceeb ntawm sucrose rau tib neeg lub cev yog li nram qab no:

1. Ua kom ntseeg tau tias muaj haujlwm ntawm lub zog.
2. Txhim kho cov haujlwm hauv lub hlwb.
3. Rov qab kho kom tiv thaiv lub siab ua haujlwm.
4. Txhawb txoj haujlwm ntawm neurons thiab striated leeg.

Sucrose deficiency ua rau lub siab tsis txaus, lub xeev ua tiav kev tsis quav ntsej, qaug zog, tsis muaj lub zog thiab kev nyuaj siab. Kev tshaj tawm ntawm cov tshuaj ua rau cov rog rog (rog dhau), kab mob ncig, rhuav tshem cov hniav, kab mob ntawm lub qhov ncauj ntawm lub qhov ncauj, tawm pob, mob khaus ntawm qhov chaw mos, thiab tseem yuav ua rau muaj kev pheej hmoo ntawm hyperglycemia thiab kev loj hlob ntawm cov ntshav qab zib.

Sucrose noj nce ntxiv thaum ib tus neeg nyob hauv qhov kev hloov pauv tas mus li, ua haujlwm ntau dhau nrog kev ua haujlwm ntawm kev txawj ntse, los yog raug rau intoxication loj.

Cov txiaj ntsig ntawm sucrose ntu - fructose thiab qabzib - yuav tsum tau muab cais cais.

Fructose yog cov tshuaj pom hauv cov txiv ntoo tshiab. Nws muaj cov qab zib qab qab thiab tsis cuam tshuam rau glycemia. Daim ntawv qhia glycemic tsuas yog 20 chav nyob.

Kev noj ntau dhau fructose ua rau tus mob qog ntshav siab, rog dhau, lub plawv dhia tsis txaus, gout, mob rog rog, thiab laus ua ntej. Hauv kev kawm txog kev tshawb fawb, nws tau ua pov thawj tias cov khoom no nrawm dua cov piam thaj ua rau cov cim ntawm kev laus.

Cov piam thaj yog cov qauv uas muaj cov carbohydrates feem ntau nyob hauv peb lub ntiaj teb. Nws ua rau glycemia nce ceev thiab ua tiav lub cev nrog lub zog tsim nyog.

Vim tias qhov tseeb tias cov piam thaj yog tsim los ntawm cov hmoov tshaib plab, kev noj ntau dhau ntawm cov khoom muaj cov starches yooj yim (mov thiab hwm hmoov) ua rau muaj ntshav qab zib ntau ntxiv.

Xws cov txheej txheem pathological txo qis ntawm kev tiv thaiv, lub raum tsis ua haujlwm, rog rog, nce lipid concentration, cov qhov txhab ua kom tsis zoo, mob hlab ntsha tawg, ntshav tawm thiab mob plawv.

Cov txiaj ntsig thiab kev phom sij ntawm cov khoom qab zib tsim

Qee tus neeg tsis tuaj yeem noj cov qab zib uas ib txwm muaj rau lwm tus. Cov lus piav qhia feem ntau rau qhov no yog mob ntshav qab zib ntawm ib daim ntawv twg.

Kuv yuav tsum siv cov khoom ntuj thiab. Qhov sib txawv ntawm cov khoom cua thiab lub cev ua kom qab zib sib txawv yog cov calories ntau thiab qhov cuam tshuam rau lub cev.

Cov tshuaj lom neeg (aspart thiab sucropase) muaj qee qhov tsis zoo: lawv cov tshuaj lom neeg cov tshuaj ua rau yem yauv thiab ua kom muaj kev loj dua ntawm cov qog ua hlav. Qhov tsuas ntxiv ntawm cov khoom cua qab zib tsuas yog cov ntsiab lus tsis muaj calorie.

Ntawm cov khoom qab zib ntuj, sorbitol, xylitol thiab fructose yog qhov nrov tshaj plaws. Lawv yog cov muaj calorie siab heev, yog li ntawd, nrog kev siv ntau dhau los ua rau muaj ceeb thawj.

Cov txiaj ntsig hloov chaw feem ntau yog stevia. Nws cov khoom muaj txiaj ntsig yog cuam tshuam nrog kev nce ntxiv ntawm lub cev tiv thaiv, ua kom ntshav siab, ua kom tawv nqaij rov qab thiab tshem tawm cov mob candidiasis.

Ntau dhau los ntawm kev noj cov khoom qab zib tuaj yeem ua rau txoj kev txhim kho ntawm cov kev tsis zoo hauv qab no:

• xeev siab, kem plab, ua xua, pw tsaug zog tsis zoo, kev nyuaj siab, tsis tuaj yeem, kiv taub hau (noj mov tsis qab),
• kev tsis haum tshuaj, suav nrog dermatitis (siv suklamat),
• kev txhim kho ntawm cov benign thiab malignant neoplasms (noj saccharin),
• zais zis mob cancer (noj thiab sorbitol),
• kev ua txhaum ntawm cov kua qaub-lub hauv paus ua kom sib luag (siv cov fructose).

Vim tias txoj kev pheej hmoo ntawm kev tsim ntau cov pathologies, cov khoom qab zib tau siv nyob rau hauv qhov tsawg. Yog tias sucrose tsis tuaj yeem noj, koj tuaj yeem maj mam ntxiv zib ntab rau hauv cov zaub mov - khoom uas muaj kev nyab xeeb thiab noj qab haus huv. Kev noj nqos ib nrab ntawm cov zib ntab tsis ua rau lub ntsej muag ntse hauv glycemia thiab nce ntawm kev tiv thaiv. Tsis tas li, maple kua txiv, uas muaj tsuas yog 5% sucrose, yog siv los ua cov kua qab zib.

Fructose feem ntau siv los ua cov qab zib rau cov neeg mob ntshav qab zib. Cov kua nplaum tsis tsim nyog rau lawv. Muaj qee kis, koj tuaj yeem siv fructose, thiab hauv qhov uas nws tsis muaj nqis. Dab tsi yog qhov txawv ntawm qabzib, fructose thiab sucrose?

Coob tus neeg paub txog cov fructose thiab cov piam thaj yog “ob tog ntawm tib lub nyiaj,” uas yog sucrose cov khoom sib txuam. Cov neeg muaj ntshav qab zib paub tias lawv raug txwv tsis pub siv khoom qab zib rau khoom noj. Vim tias qhov no, ntau tus neeg nyiam siv cov txiv hmab txiv ntoo qab zib, tab sis nws puas muaj kev nyab xeeb zoo li nws zoo li thaum xub thawj siab? Cia peb sim paub seb dab tsi yog qhov txawv ntawm ob lub monosaccharides.

Txiv hmab txiv ntoo monosaccharide yog dab tsi?

Fructose thiab piam thaj ua ke yog ib qho sucrose molecule. Cov kws tshawb fawb tau ua pov thawj tias cov txiv hmab txiv ntoo monosaccharide tsawg kawg yog ib nrab ntawm cov khoom qab zib tshaj qab zib. Nws yog qhov txawv txav, tab sis yog tias sucrose thiab txiv hmab txiv ntoo monosaccharide siv tib lub npaum li cas, tom kawg kuj yuav qab zib dua. Tab sis nyob rau hauv cov nqe lus ntawm caloric ntsiab lus, sucrose ntau tshaj nws cov ntsiab lus.

Txiv hmab txiv ntoo monosaccharide ntau dua kom zoo rau cov kws kho mob, nws tau qhia kom siv nws es tsis txhob qab zib. Qhov no yog vim qhov tseeb tias nws tau nqus rau hauv cov ntshav ob zaug qeeb dua cov piam thaj. Lub sijhawm yaug yog kwv yees li 20 feeb. Nws kuj tsis ua rau puas tsuaj rau kev tso tawm ntau ntawm cov tshuaj insulin. Vim tias muaj cov cuab yeej no, cov neeg mob ntshav qab zib tuaj yeem tsis kam qab zib los ntawm kev siv cov khoom raws li cov monosaccharide no. Qhov no yog qhov sib txawv loj ntawm fructose thiab sucrose thiab qabzib.

Tab sis nws tsis yog li ntawd tsis muaj mob, rau ntau yam, ntau dua 50 g ib hnub ua rau kev ua kom lub cev thiab tsam plab. Cov kws tshawb fawb tau pom tias cov ntaub so ntswg adipose nce ntau ntawm fructose.Qhov no yog vim qhov tseeb tias nws tau ua tiav hauv daim siab, thiab qhov khoom hauv lub cev no raug txwv nyob hauv txoj kev muaj peev xwm ntawm cov tshuaj yeeb dej caw. Thaum lub monosaccharide ntau ntau nkag mus rau hauv lub cev, lub siab tsis tuaj yeem kho, thiab cov khoom no hloov mus ua rog.

Cov txiaj ntsig ntawm sucrose thiab kua txiv qab zib hauv ntshav qab zib

Cov piam thaj los yog qab zib, uas yog qhov ib txwm yog qhov txwv tsis pub siv rau hauv cov ntshav qab zib, vim tias cov tshuaj no ua rau muaj kev cuam tshuam ntawm lub cev tam sim ntawd - kev tso tawm ntawm cov tshuaj insulin. Thiab yog tias cov tshuaj insulin tsis txaus (1 yam mob) lossis koj tus txiav tsis xav noj koj cov insulin (mob 2 yam), cov ntshav qabzib nce siab.

Qhov txiaj ntsig ntawm fructose hauv ntshav qab zib tsis zoo. Nws tuaj yeem siv, tab sis hauv qhov tsawg tsawg. Yog tias ib tus tib neeg tsis muaj lub qab zib muab los ntawm cov txiv hmab txiv ntoo monosaccharide ib hnub, nws zoo dua los siv lwm cov khoom qab zib hauv kev ntxiv. Hauv hom 2 Ntshav Qab Zib, qab zib muaj kev phom sij rau cov neeg mob ntau dua li fructose. Nws yog qhov zoo dua kom tsis txhob muaj nws hauv txhua yam khoom: xyuas lawv cov kev sib xyaw thiab tsis txhob ua noj tais diav thiab khaws cia nrog sucrose.

Qhov sib txawv ntawm fructose thiab sucrose

1. Txiv hmab txiv ntoo monosaccharide tsis yog qhov nyuaj hauv cov qauv, yog li nws yooj yim dua rau nqus hauv lub cev. Qab zib yog ib qho tsis muaj txiaj ntsig, yog li kev nqus yuav siv sijhawm ntev dua.
2. Qhov txiaj ntsig ntawm fructose rau cov neeg mob ntshav qab zib yog qhov insulin tsis koom nrog nws nqus. Qhov no yog nws qhov sib txawv ntawm cov piam thaj.
3. Qhov tshuaj monosaccharide no qab qab qab dua li sucrose, qee qhov siv rau hauv cov koob tshuaj me me rau menyuam yaus. Hauv qhov no nws tsis muaj teeb meem tsis muaj qab zib los yog fructose yuav siv rau hauv cov tais diav, kev cia siab rau ib tus neeg ntawm cov tshuaj no yuav tsum tau coj mus rau hauv tus account.
4. Cov txiv hmab txiv ntoo qab zib tsis yog ib qho txiaj ntsig ntawm lub zog "ceev". Txawm tias thaum tus mob ntshav qab zib ua mob txaus rau qhov tsis txaus cov kua nplaum (nrog lub qog ntshav qab zib), cov khoom uas muaj fructose yuav tsis pab nws. Hloov chaw, koj yuav tsum tau siv cov qhob noom xim kasfes lossis kua qab zib ua kom rov qab nws cov qib qub hauv cov ntshav.

Caloric cov ntsiab lus ntawm monosaccharides, cov tshuaj tso cai

Cov kua nplaum thiab fructose muaj kwv yees li qhov tseem ceeb. Qhov kawg yog txawm tias kaum tawm ntau dua - 399 kcal, thaum thawj monosaccharide - 389 kcal. Nws hloov tawm tias lub ntsiab lus caloric ntawm ob yam no tsis txawv ntau. Tab sis nws yog qhov muaj txiaj ntsig ntau dua rau kev siv fructose hauv kev siv me me rau ntshav qab zib. Rau cov neeg mob zoo li no, tus nqi tso cai ntawm no monosaccharide ib hnub yog 30 grams. Nws yog ib qho tseem ceeb kom soj ntsuam cov kev mob:

• Cov tshuaj no nkag mus rau hauv lub cev tsis yog hauv nws daim ntawv ntshiab, tab sis hauv cov khoom lag luam.
• Niaj hnub saib xyuas ntshav qabzib kom tsis txhob muaj kev phais.

Kev siv cov txiv hmab txiv ntoo monosaccharide hauv ntshav qab zib

Peb tau txiav txim siab yuav ua li cas zaum ob ntawm monosaccharide txawv ntawm cov piam thaj. Tab sis dab tsi yog qhov zoo dua los siv ua khoom noj, cov zaub mov dab tsi muaj qhov phom sij zais rau cov neeg mob ntshav qab zib?

Muaj cov khoom nyob rau hauv uas fructose thiab qab zib yuav luag tib yam. Rau cov neeg muaj kev noj qab haus huv, qhov tandem no zoo tshaj plaws, txij li ob yam tshuaj no tsuas yog ua ke nrog kev sib txuam tau muab zom sai dua, tsis tas nyob hauv lub cev hauv daim ntawv ntawm cov roj muaj roj. Rau cov neeg mob ntshav qab zib, lawv siv tsis pom zoo. Xws li cov khoom lag luam muaj cov txiv hmab txiv ntoo siav thiab ntau yam tais diav los ntawm lawv, suav nrog kev khaws cia. Dej qab zib los ntawm cov khw muag khoom yog contraindicated, raws li lawv muaj fructose thiab qab zib tib lub sijhawm.

Coob leej neeg nug hais tias, “Puas yog qab zib lossis fructose ntxiv rau haus dej qab zib rau cov ntshav qab zib?” Lo lus teb yooj yim: “Tsis muaj dab tsi los ntawm cov saum toj no!” Qab zib thiab nws cov khoom xyaw kuj ua rau muaj teeb meem ib yam. Cov tom kawg hauv nws daim ntawv ntshiab muaj txog 45% sucrose, txaus rau kev ua kom tsis zoo ntawm tus neeg mob ntshav qab zib.

Kev Siv Monosaccharide los ntawm Cov Menyuam

Cov niam qee zaum muaj kev xaiv: fructose lossis qab zib yuav pab tau rau menyuam yaus ua khoom qab zib. Cov tshuaj dab tsi zoo dua los xaiv cov khoom lag luam nrog?

• Nws yog qhov zoo dua nqus, txo txoj kev thauj mus rau seem ntawm tus menyuam yaus.
• Tsis ua rau diathesis.
• Tiv thaiv kev sib npaug ntawm cov kab mob pathogenic hauv cov me nyuam lub qhov ncauj.
• Muab zog ntau dua.
• Nrog ntshav qab zib hom 1, koj tuaj yeem txo qhov koob tshuaj insulin.

Tab sis koj yuav tsum nco ntsoov, fructose lossis qab zib yuav siv, koj tsis tuaj yeem ua phem rau lawv tshwj xeeb tshaj yog thaum tseem hluas, txhawm rau tiv thaiv kev txhim kho ntshav qab zib.

Glycated (glycosylated) hemoglobin. Kuaj ntshav rau glycated hemoglobin

Glycated (glycosylated) hemoglobin yog ib feem ntawm tag nrho hemoglobin ncig hauv cov ntshav uas khi rau cov piam thaj. Qhov ntsuas no yog ntsuas hauv%. Qhov ntau cov ntshav qab zib, ntau dua% cov hemoglobin yuav raug glycated. Qhov no yog ib qho kev ntsuas ntshav tseem ceeb rau ntshav qab zib lossis xav tias ntshav qab zib. Nws qhia tau tseeb heev txog qib ntshav siab nyob hauv ntshav ntshav dhau 3 lub hlis dhau los. Tso cai rau koj los kuaj ntshav qab zib hauv lub sijhawm thiab pib kho. Lossis tso siab rau tus neeg yog tias nws tsis muaj ntshav qab zib.

• Yuav npaj thiab kuaj ntshav li cas,
• Hom ntawm glycated hemoglobin - lub rooj yooj yim,
• Glycated hemoglobin hauv cov poj niam cev xeeb tub
• Yuav ua li cas yog tias qhov txiaj ntsig nce,
• Kev kuaj mob ntshav qab zib, hom 1 thiab hom 2 ntshav qab zib mellitus,
• Saib xyuas qhov ua tau zoo ntawm kev kho ntshav qab zib.

Lwm lub npe rau qhov ntsuas no:

• glycosylated hemoglobin,
• hemoglobin A1C,
• HbA1C,
• lossis tsuas yog A1C.

Kev kuaj ntshav rau glycated hemoglobin yooj yim rau cov neeg mob thiab kws kho mob. Nws muaj cov txiaj ntsig zoo dua ntawm qhov ntsuas cov ntshav qab zib kom yoo thiab dhau 2-teev cov ntsuas cov piam thaj hauv qab. Dab tsi yog cov zoo:

• glycated hemoglobin tsom xam tau txhua lub sijhawm, tsis tas yuav ntawm lub plab khoob,
• nws yog qhov tseeb dua li kev soj ntsuam cov ntshav qab zib kom nruj, tso cai rau koj tshawb xyuas ntshav qab zib ua ntej,
• nws tau nrawm dua thiab yooj yim dua li 2-teev kev ntsuas ntshav qab zib,
• tso cai rau koj kom teb meej cov nqe lus nug seb tus neeg puas muaj ntshav qab zib lossis tsis,
• pab xyuas kom paub tias cov mob ntshav qab zib tswj tau nws cov ntshav qab zib li cas nyob rau 3 lub hlis dhau los,
• glycated hemoglobin tsis cuam tshuam los ntawm lub sijhawm nuances zoo li mob khaub thuas lossis xwm txheej ntxhov siab.

Cov lus qhia zoo: thaum koj mus kuaj ntshav - tib lub sijhawm kuaj xyuas koj qib ntshav hemoglobin HbA1C.

Qhov txiaj ntsig ntawm kev txheeb xyuas no TSIS YOG nyob ntawm:

• lub sij hawm ntawm ib hnub thaum lawv pub ntshav,
• lawv muab nws tso rau ntawm lub plab lossis tom qab noj mov tag,
• noj lwm yam tshuaj tsis yog ntshav qab zib tshuaj,
• kev xav hauv lub xeev ntawm tus neeg mob
• mob khaub thuas thiab lwm yam mob.

Vim li cas thiaj li kuaj ntshav rau glycated hemoglobin

Qhov ib, txhawm rau kuaj ntshav qab zib lossis ntsuas qhov txaus ntshai tus neeg muaj ntshav qab zib. Thib ob, txhawm rau kom ntsuas cov ntshav qab zib kom tus neeg mob tswj tau tus mob thiab tswj ntshav qab zib kom nyob li qub.

Txog kev kuaj mob ntshav qab zib, qhov ntsuas no tau siv tiav (raws li kev pom zoo los ntawm World Health Organization) txij li xyoo 2011, thiab nws tau yooj yim rau cov neeg mob thiab cov kws kho mob.

Feem ntau ntawm glycated hemoglobin

Qhov qis dua theem ntawm glycated hemoglobin hauv tus neeg mob, qhov zoo dua nws cov ntshav qab zib tau raug them rov qab hauv 3 lub hlis dhau los.

Kev sib raug zoo ntawm HbA1C rau cov ntshav qabzib feem ntau hauv cov ntshav ntshav tau li 3 lub hlis

• Yuav kho li cas rau hom ntshav qab zib 2: txheej txheem ib qib zuj zus
• Cov tshuaj ntshav qab zib hom 2: cov ncauj lus kom ntxaws
• Siofor thiab Glucofage ntsiav tshuaj
• Li cas los kawm kom txaus siab rau kev kawm siv lub cev

Kev kuaj ntshav rau glycated hemoglobin: qhov zoo thiab tsis zoo

Kev kuaj ntshav rau HbA1C, piv nrog kev ntsuas cov ntshav qab zib, muaj ntau qhov zoo:

• ib tug neeg tsis tas yuav muaj lub plab khoob
• cov ntshav tau yooj yim khaws cia rau hauv lub raj ntsuas kom txog thaum tshuaj ntsuam tam sim ntawd (qhov kev tiv thaiv kev puas tsuaj),
• yoo plasma ntshav qab zib tuaj yeem sib txawv heev vim kev ntxhov siab thiab kev kis kab mob, thiab glycated hemoglobin yuav ruaj khov dua

Kev kuaj ntshav rau glycated hemoglobin tso cai rau koj los kuaj ntshav qab zib thaum ntxov, thaum kev txheeb xyuas cov ntshav qab zib tseem qhia tau tias txhua yam ua haujlwm.

Kev tsis zoo ntawm cov ntshav glycated hemoglobin kuaj ntshav:

• tus nqi ntau dua piv rau kev kuaj ntshav hauv ntshav hauv ntshav (tab sis sai thiab yooj yim!),
• Hauv qee cov tib neeg, txoj kev sib txuam sib luag ntawm qib HbA1C thiab qhov qis nruab nrab ntawm cov piam thaj txo
• nyob rau hauv cov neeg mob uas mob ntshav tsis txaus thiab hemoglobinopathies, cov kev tshuaj ntsuam tau cuam tshuam,
• hauv qee thaj tsam ntawm lub tebchaws, cov neeg mob yuav tsis muaj chaw sim rau qhov kev ntsuas no,
• nws xav tias yog tias ib tus neeg tau noj tshuaj ntau ntawm cov vitamins C thiab / lossis E, ces nws tus nqi ntawm glycated hemoglobin yog dag ntxias qis (tsis muaj pov thawj!),
• qes ntawm cov thyroid hormones txaus tuaj yeem ua rau HbA1C nce ntxiv, tab sis cov ntshav qab zib tsis nce ntxiv.

Yog tias koj txo qis HbA1C tsawg kawg 1%, qhov pheej hmoo ntawm cov ntshav qab zib yuav txo qis npaum li cas:

Glycated hemoglobin thaum cev xeeb tub

Glycated hemoglobin thaum cev xeeb tub yog ib qho kev sim uas yuav ua tau los tswj ntshav qab zib. Txawm li cas los xij, qhov no yog qhov kev xaiv tsis zoo. Thaum cev xeeb tub, nws zoo dua tsis txhob pub ntshav glycated hemoglobin, tab sis kom kuaj xyuas tus poj niam cov ntshav qab zib hauv lwm txoj kev. Cia peb piav qhia vim li cas qhov no thiaj yog, thiab tham txog cov kev xaiv kom raug dua.

Dab tsi yog qhov phom sij ntawm cov piam thaj ntau ntxiv hauv cov poj niam cev xeeb tub? Ua ntej tshaj plaws, qhov tseeb tias tus me nyuam hauv plab loj dhau, thiab vim qhov no yuav muaj kev yug me nyuam nyuaj. Txoj kev pheej hmoo rau leej niam thiab tus me nyuam nce ntxiv. Tsis hais txog qhov yuav tshwm sim ntev ntev rau ib qho ntawm lawv. Muaj ntshav qab zib ntau ntxiv thaum cev xeeb tub ua rau cov hlab ntshav, raum, qhov muag pom, thiab lwm yam Cov txiaj ntsig ntawm qhov no yuav tshwm sim tom qab. Kev muaj menyuam yog ib nrab ntawm kev sib ntaus sib tua. Nws yog tsim nyog tias nws tseem muaj kev noj qab haus huv txaus rau nws txoj kev loj hlob ...

Cov piam thaj hauv ntshav thaum cev xeeb tub tuaj yeem nce ntxiv txawm tias cov poj niam uas tsis tau yws yws txog lawv txoj kev noj qab haus huv ua ntej. Muaj ob qho tseem ceeb nuances ntawm no:

1. Cov piam thaj ntau tsis ua rau muaj mob dabtsi. Feem ntau tus poj niam tsis xav tias yog dab tsi, txawm hais tias nws muaj txiv hmab txiv ntoo loj heev - loj heev hnyav 4-4,5 kg.
2. Qab zib nce tsis nyob ntawm lub plab khoob, tab sis tom qab noj mov. Tom qab noj mov tas, nws cia kom tau nce li 1-4 teev. Lub sijhawm no, nws tabtom ua nws txoj haujlwm rhuav tshem. Fasting suab thaj yog feem ntau ib txwm. Yog tias cov piam thaj yog tsa rau ntawm lub plab khoob, ces qhov teeb meem tsis zoo.

Vim li cas thiaj li kuaj ntshav rau glycated hemoglobin kuj tsis haum? Vim tias nws hnov ​​mob heev. Glycated hemoglobin hlob zoo tsuas yog tom qab cov ntshav qab zib tau cia kom nce hauv 2-3 lub hlis. Yog tias tus poj niam nce qab zib, ces qhov no feem ntau tsis tshwm sim ntxov dua li 6 lub hlis ntawm kev xeeb tub. Tib lub sijhawm, glycated hemoglobin yuav raug nce tsuas yog thaum 8-9 hlis, twb dhau los ua ntej khoom xa tuaj. Yog tias tus poj niam cev xeeb tub tsis tswj nws cov piam thaj ua ntej, tom qab ntawd yuav muaj qhov tsis zoo rau nws thiab nws tus menyuam.

Yog tias glycated hemoglobin thiab qhov kev kuaj ntshav ntawm cov ntshav qab zib tsis haum, yog li yuav ua li cas xyuas cov suab thaj hauv cov poj niam cev xeeb tub? Teb: nws yuav tsum tau kuaj xyuas tom qab noj mov tas li txhua 1-2 asthiv. Txhawm rau ua qhov no, koj tuaj yeem coj mus kuaj ntshav ntev li 2-teev nyob hauv chav kuaj. Tab sis qhov no yog qhov xwm txheej ntev thiab laj siab. Nws yooj yim los yuav qhov ntsuas cov ntshav qab zib hauv tsev thiab ntsuas ntsuas qab zib 30, 60 thiab 120 feeb tom qab noj mov. Yog tias cov txiaj ntsig tsis siab tshaj 6.5 mmol / l - zoo heev. Hauv qhov ntau ntawm 6.5-7.9 mmol / l - siab ntev. Los ntawm 8.0 mmol / L thiab siab dua - tsis zoo, koj yuav tsum ntsuas kom txo cov suab thaj.

Khaws cov zaub mov uas tsis muaj carbohydrate ntau, tab sis noj txiv hmab txiv ntoo, carrots, thiab beets txhua hnub los tiv thaiv ketosis. Nyob rau tib lub sijhawm, cev xeeb tub tsis yog lub laj thawj tso cai rau koj tus kheej kom noj ntau nrog cov khoom qab zib thiab hmoov. Xav paub ntaub ntawv ntau ntxiv, saib cov lus txog Kev Xeeb Mob Ntshav Qab Zib thiab Ntshav Qab Zib Gestational.

Sab Sij Huam Glidiab mv:

Los ntawm cov txheej txheem hauv plab: tsis tshua muaj - tsis nco qab, ntuav, ntuav, raws plab, mob epigastric.

Los ntawm cov kab mob hemopoietic: nyob rau qee kis - thrombocytopenia, agranulocytosis lossis leukopenia, ntshav liab (feem ntau thim rov qab).

Los ntawm cov kab ke endocrine: nrog kev siv ntau dhau - hypoglycemia.

Ua xua: tawv nqaij ua pob, khaus.

Cov tshuaj rau txoj kev siv tshuaj:

Mob ntshav qab zib insulin-tiv thaiv kab mob ntshav qab zib hom (hom I), ketoacidosis, mob ntshav qab zib thiab ua rau tsis nco qab, ua rau lub raum thiab lub cev tsis ua haujlwm zoo, mob siab rau sulfonylureas thiab sulfonamide npaj. Kev siv tib lub ntsej muag ntawm gliclazide thiab imidazole derivatives (suav nrog miconazole).

Cov lus qhia tshwj xeeb rau kev siv Glidiab mv.

Gliclazide yog siv los kho cov ntshav qab zib tsis yog-insulin nyob rau hauv kev sib xyaw nrog kev noj zaub mov kom muaj calorie tsawg, noj cov zaub mov qis.

Thaum kho, koj yuav tsum tau soj qab xyuas kom cov qib ntawm cov piam thaj hauv cov ntshav ntawm lub plab thiab tom qab noj mov, kev hloov pauv txhua hnub nyob hauv qib qabzib.

Kev phais mob lossis kev decompensation ntawm ntshav qab zib mellitus, nws yog ib qho tsim nyog yuav tsum coj mus rau hauv tus account qhov tau los ntawm kev siv tshuaj insulin.

Nrog rau kev txhim kho cov ntshav qog ntshav qab zib, yog tias tus neeg mob nco qab, qabzib (lossis kua qab zib) yog tshuaj hauv. Yog tias tsis nco qab, tso ntshav qabzib lossis glucagon sc, intramuscularly lossis intravenously raug tswj hwm. Tom qab nws rov qab nco qab, nws yog ib qho tsim nyog yuav tsum tau muab rau cov neeg mob zaub mov nplua nuj nyob hauv cov khoom noj kom paub zoo kom tsis txhob rov qab txhim kho kev mob hypoglycemia.

Nrog rau kev siv kev sib txuas ntawm gliclazide nrog verapamil, yuav tsum tau saib xyuas cov ntshav qabzib ntau ntxiv, nrog acarbose, ua tib zoo saib xyuas thiab kho cov tshuaj regimen ntawm hypoglycemic tus neeg sawv cev yog qhov yuav tsum tau ua.

Kev siv ua ke ntawm gliclazide thiab cimetidine tsis pom zoo.