Cov tshuaj Lovastatin: cov lus qhia rau kev siv, analogues, lus piav qhia, muaj pes tsawg leeg thiab tshuaj xyuas

Qhov teeb meem ntawm cov ntshav siab siab txhawj xeeb ntau tus neeg. Qhov no yog vim qhov tseeb tias qhov xwm txheej zoo li no tuaj yeem ua rau lub siab tsis ua haujlwm ntawm lub plawv thiab vascular system tag nrho. Txhawm rau tshem tawm hyperlipoproteinemia, nws yog ib qho tsim nyog yuav tsum tsis txhob noj txoj cai, tab sis kuj noj qee yam tshuaj.

Txoj hauv kev muaj txiaj ntsig zoo tshaj plaws los txo cov ntshav siab tus roj yog suav tias yog cov tshuaj "Lovastatin." Cov lus qhia rau kev siv, nqe, tshuaj xyuas, tshuaj pom tseeb thiab kab mob sib kis ntawm cov tshuaj no yuav nthuav qhia hauv qab no. Koj tseem yuav kawm txog dab tsi cov kws txawj hais txog nws thiab cov neeg tawm tswv yim zoo li cas tawm.

Daim ntawv, muaj pes tsawg leeg, ntim khoom thiab piav qhia ntawm cov khoom siv tshuaj ntsuab

Cov tshuaj "Lovastatin", cov lus qhia rau kev siv uas tau ntim hauv cov thawv ntawv cardboard, tau muag ua cov qauv dawb thiab puag ncig. Cov nquag ua yeeb yam hauv cov tshuaj no yog lovastatin. Raws li rau cov koomhaum pabcuam, lawv suav nrog lactose monohydrate, hmoov txhuv nplej siab, cellulose, ascorbic acid, butyl hydroxyanisole, citric acid thiab magnesium stearate.

Cov tshuaj yog tawm hauv cov hlwv cell thiab pob khoom ntawm cardboard, feem.

Tus txheej txheem ntawm kev ua ntawm cov tshuaj

Lub hauv paus ntsiab lus ntawm kev ua yeeb tshuaj "Lovastatin" yog dab tsi? Cov lus qhia rau kev siv, kev qhia paub me me tias LP cov neeg txais lub siab tswj cov ntsiab lus ntawm lipoproteins hauv cov ntshav. Lawv muab tau los ntawm nws los ntawm kev sib cuam tshuam nrog cov tau txais kev qhia. Raws li qhov tshwm sim, cov roj (cholesterol) tau muab tso ua ke hauv cov kab mob siab.

Lub hauv paus ntsiab lus ntawm kev txiav txim siab ntawm cov tshuaj hauv nqe lus nug tau piav qhia los ntawm kev tsuam ntawm 3-hydroxy-3-methylglutaryl-coenzyme A reductase. Qhov no yog ib qho enzyme nrog kev koom nrog uas qhov synthesis ntawm cov cholesterol yog nqa tawm.

Txo kev tsim cov roj (cholesterol) yuav ua rau muaj kev nce ntxiv ntawm LP receptors rau hepatocytes. Raws li cov txiaj ntsig ntawm no, cov txheej txheem ntawm kev tshem tawm lipoproteins tsawg ntom ntawm cov ntshav tau nrawm dua, thiab tag nrho cov roj (cholesterol), cov roj cholesterol thiab cov roj (cholesterol) nruab nrab yuav raug txo.

Cov yam ntxwv ntawm cov tshuaj

Dab tsi lwm cov khoom tsis ua cov Lovastatin ntsiav tshuaj muaj? Cov lus qhia rau kev siv (tus nqi, tshuaj xyuas tau nthuav tawm kawg ntawm tsab xov xwm) qhia tias qhov cuab yeej no muaj peev xwm txo cov ntsiab lus ntawm apolipoprotein B thiab triglycerides, zoo li nce me ntsis ntawm cov qib siab lipoproteins.

Kev kho mob nyhuv tom qab noj cov tshuaj pom tshwm tom qab ob lub lis piam, thiab qhov siab tshaj plaws - tom qab txog ib hlis thiab ib nrab. Txawm li cas los xij, nws tseem mob ntev li rau lub lis piam tom qab tsum tsis siv tshuaj.

Qhov ua tau zoo ntawm cov tshuaj uas siv ntev ntev tsis txo. Nws tseem yuav tsum tau sau tseg tias nws tau txais los ntawm cov biocultures ntawm Aspergillus terreus thiab Monascus ruber.

Kinetic khoom

Lovastatin yuav siv sijhawm ntev li cas? Cov lus qhia rau kev siv (tus nqi tshuaj yog tsis siab heev) thov tias qhov nqus ntawm cov tshuaj no los ntawm cov hnyuv tshwm sim maj mam tshwm sim. Ntxiv mus, nws txo qhov kev nqus ntawm cov ntsiav tshuaj ntawm lub plab tas.

Lub bioavailability ntawm cov tshuaj no yog heev tsawg (kwv yees li 30% ntawm cov koob tshuaj noj). Tom qab txog plaub teev, kev siab tshaj plaws ntawm cov tshuaj hauv cov ntshav tau tiav. Tom qab lwm hnub nws txo qis thiab yog li 10% ntawm qhov siab tshaj.

Cov tshuaj hauv cov lus nug yog 95% ua txhua yam rau cov protein plasma. Kev tshem tawm ntawm cov tshuaj nrog ib zaug tshuaj yog pom nyob rau 3 hnub.

Tshuaj Lovastatin yog dab tsi? Cov lus qhia txog kev siv xov xwm qhia tias qhov no yog khoom lag luam. Tom qab thawj kab ntawv dhau los ntawm daim siab, nws yuav siv daim ntawv nquag.

Cov tshuaj yog metabolized los ntawm isoenzymes. Nws ib nrab-lub neej yog 180 feeb. Lub ntsiab lus nquag ntawm cov tshuaj, nrog rau nws cov metabolites, raug tawm los ntawm lub raum thiab dhau los ntawm cov hnyuv.

Kev qhia rau kev noj tshuaj

Nyob rau hauv lub xub ntiag ntawm tej yam mob dab tsi yog cov neeg mob sau tshuaj Lovastatin ntsiav tshuaj? Cov lus qhia rau kev siv (cov lus piav qhia, muaj pes tsawg leeg ntawm cov tshuaj tau nthuav tawm thaum pib ntawm tsab xov xwm) qhia tias cov tshuaj no muaj txiaj ntsig zoo rau thawj tus mob hypercholesterolemia (hom IIb thiab hom IIa lipolipoproteinemia) nrog cov ntshav siab (LDL) cov ntsiab lus (yog tias kev noj zaub mov noj hauv cov neeg muaj kev pheej hmoo ntawm kev txhim kho mob rau cov ntshav atherosclerosis yog qhov tsis muaj txiaj ntsig) , thiab ntxiv rau kev sib xyaw ua ke hypertriglyceridemia thiab hypercholesterolemia.

Nws yuav tsum raug sau tseg tias cov tshuaj hauv cov lus nug feem ntau tau kho rau atherosclerosis.

Cov kev tiv thaiv tsis zoo rau kev siv prodrugs

Dab tsi ntawm tus neeg mob tsis pom zoo siv Lovastatin ntsiav tshuaj? Cov lus qhia rau kev siv (kev kho mob nrog cov tshuaj no yuav tsum yog ntawv sau los ntawm kws kho mob nkaus xwb) qhia tias cov tshuaj no yog sib kis thaum muaj kab mob siab, kev xeeb tub lossis nws qhov tshwm sim, muaj kev cuam tshuam ntau ntxiv ntawm kev hloov pauv ntawm keeb kwm tsis meej, nrog rau lub sijhawm pub niam mis, nyob rau hauv tus neeg mob hnyav (dav dav) thiab nce rhiab siab los lovastatin.

Tsis tas li, cov tshuaj hauv cov lus nug tsis raug txiav txim siab thaum muaj hnub nyoog me, nrog myopathy thiab cholestasis.

Nws yog txwv tsis pub coj cov tshuaj cawv nrog cawv. Nrog kev ceev faj, nws yog kws kho rau cov neeg mob tom qab kev mob caj dab txoj hlab ntshav bypass grafting.

Cov tshuaj "Lovastatin": cov lus qhia rau kev siv

Nqe, analogues ntawm cov cuab yeej no yuav txiav txim siab me ntsis.

Raws li cov lus qhia txuas nrog, Lovastatin ntsiav tshuaj yuav tsum tau noj ntawm qhov ncauj thaum noj hmo ib zaug ib hnub.

Nyob rau hauv xws li pathological mob raws li hyperlipidemia, cov tshuaj yog tshuaj nyob rau hauv ib qho nyiaj ntawm 10-80 mg ib zaug (qhov koob tshuaj nyob ntawm qhov mob hnyav ntawm tus kab mob).

Kev kho mob nrog cov tshuaj hauv nqe lus nug pib nrog kev txhaj tshuaj me me. Tom qab ntawd nws yog maj mam nce. Kev noj tshuaj ntau tshaj plaws txhua hnub, sib npaug 80 mg, tuaj yeem noj ib zaug lossis ob zaug ib hnub (thaum sawv ntxov thiab ua ntej yuav mus pw). Kev xaiv ntawm kev siv tshuaj kho kom zoo yog nqa nrog ib nrab ntawm ib hlis.

Lovastatin raug sau tseg li cas rau kev mob ntshav siab? Cov lus qhia rau kev siv qhia tias nrog tus kab mob zoo li no, cov tshuaj muaj tshuaj nyob rau hauv ib koob ntawm 20-40 mg. Yog tias qhov tshuaj pom tseeb ntawm cov tshuaj tsis muaj txiaj ntsig, ces nws tau nce rau 60-80 mg.

Thaum cov tshuaj ua ke nrog fibrates lossis nicotinic acid, nws cov tshuaj yuav tsum tsis pub ntau dua 20 mg ib hnub twg.

Phiv Txheej Xwm

Puas yog Lovastatin noj tshuaj ua rau muaj kev phiv? Cov lus qhia rau kev siv qhia pom cov xwm txheej tsis zoo hauv qab no:

cataracts, mob taub hau,
optic atrophy, kiv taub hau,
insomnia, pw tsis tsaug zog, ntxhov siab vim, feem ntau qaug zog, kab mob khaub thuas,
mob leeg, myalgia, myositis
cov neeg noj cov tshuaj nicotinic acid, Cyclosporin lossis Gemfibrozil, ntau ntxiv yuav ua rau mob rhabdomyolysis,
thrombocytopenia, hemolytic anemia,
Kev kub siab, biliary cholestasis, xeev siab, mob siab, mob plab, saj tsis qab, txhawm, cholestatic jaundice, raws plab,
nce kev ua si ntawm creatine phosphokinase thiab daim siab transaminases,
kev nce bilirubin thiab alkaline phosphatase,
Quincke's edema, tawm pob, khaus, khaus, mob caj dab, tso zis,
alopecia thiab tsawg potency.

Tshuaj ntau dhau

Nrog kev tswj hwm qhov kev tsis txaus ntseeg ntawm kev nce siab ntawm cov tshuaj, cov tsos mob tshwj xeeb tsis pom hauv tus neeg mob.

Thaum soj ntsuam cov kab mob pathological, cov neeg raug tsim txom ntxuav nrog lub plab thiab sau kom tsawg ntawm sorbents. Tsis tas li, tus neeg mob tau saib xyuas rau cov haujlwm tseem ceeb, lub siab ua haujlwm thiab creatine phosphokinase kev ua si.

Yeeb tshuaj sib cuam tshuam

Kev siv lub sij hawm ntau ntawm cov kua txiv kab ntxwv qaub, nrog rau Gemfibrozil thiab Fenofibrat, ua rau muaj kev pheej hmoo siab ntawm kev txhim kho myopathies.

Kev noj tshuaj nrog nicotinic acid, Clarithromycin, Erythromycin, Cyclosporin, tshuaj tua kab mob (Itraconazole, Ketoconazole), Nefazodone thiab Ritonavir ua rau kev nce siab hauv cov tshuaj lom hauv cov ntshav, nrog rau cov leeg mob. cov nqaij thiab txoj kev pheej hmoo ntawm kev tsim myopathy.

Kev tswj hwm ntawm "Lovastatin" nrog "Warfarin" ua rau muaj kev pheej hmoo los ntshav.

Cov tshuaj "Colestyramine" txo cov kev tsis sib haum xeeb ntawm cov tshuaj hauv cov lus nug. Yog li ntawd, lub sijhawm sib nrug ntawm lawv txoj kev nkag mus yuav tsum yog tsawg kawg 2-4 teev.

Tus nqi ntawm cov tshuaj thiab nws analogues

Tam sim no, nws tsis tuaj yeem yuav cov tshuaj hauv khw muag tshuaj hauv Moscow thiab lwm lub nroog ntawm Russia. Yog tias tsim nyog, nws tuaj yeem txiav txim mus thoob Lub Ntiaj Teb Thoob Ntiaj Teb. Cov nqi hauv cov khw muag tshuaj online sib txawv. Cov tshuaj no tuaj yeem muas hauv thaj tsam ntawm 300-600 rubles.

Yog tias tsim nyog, ces cov tshuaj hauv cov lus nug tuaj yeem hloov nrog cov tshuaj xws li Apextatin, Fluvastatin, Cardiostatin, Iinvastin, Vero-Lovastatin, Pravastatin, Holetar, Lovasterol, Mevacor , Mevinacor, Lovacor.

Tshuaj Ntsuam Xyuas

Tam sim no koj paub cov tshuaj zoo li Lovastatin yog dab tsi. Cov lus qhia, muaj pes tsawg leeg, siv, tshuaj sib piv ntawm cov tshuaj no tau piav qhia hauv kab lus no.

Raws li cov kws tshaj lij, lipid-txo cov tshuaj yog siv rau hauv kev kho mob nyuaj, tseem ua rau kev tiv thaiv atherosclerosis thiab nws cov teeb meem.

Lub hauv paus ntsiab lus ntawm kev ua ntawm cov tshuaj no yog txo cov ntsiab lus ntawm atherogenic lipoproteins hauv ntshav

Raws li cov kws kho mob, tam sim no, ntau qhov kev paub tau tau txais hauv kev siv kho mob ntawm Lovastatin. Nws yog ib qho tshuaj muaj kev nyab xeeb tshaj plaws. Cov tshuaj no muaj tus kam rau siv tau lub sij hawm kho kom zoo.

Kev yws txog cov kev mob tshwm sim tsawg heev hauv kev tshuaj xyuas cov neeg mob. Qee zaum cov tshuaj no tuaj yeem ua rau flatulence, raws plab, mob plab, cem quav, pw tsaug zog thiab mob leeg. Feem ntau, kev tawm tsam no ploj mus ob lub lis piam tom qab pib kho los yog vim muaj ib koob tshuaj txo.

Cov tshuaj Lovastatin: mechanism ntawm kev txiav txim thiab tshuaj xyuas

Pab pawg ntawm cov statins (cov tshuaj txo cov roj (cholesterol) txo qis) suav nrog qhov tshuaj Lovastatin zoo. Cov tshuaj no siv tsis yog siv rau hauv kev kho mob hypercholesterolemia, hyperlipoproteinemia, tab sis kuj tseem nyob hauv kev tiv thaiv ntawm cov kab mob plawv.

Cov tshuaj yuav tsum tau siv ua ke nrog nrog cov khoom noj tshwj xeeb, kev tawm dag zog thiab kev ntsuas lub cev. Hauv tsab xov xwm no, koj tuaj yeem kawm paub ntau ntxiv txog Lovastatin, cov lus qhia rau kev siv, tus nqi, tshuaj xyuas, analogues.

Cov lus qhia rau kev siv tshuaj

Lovastatin 20 mg lossis 40 mg yog tsim nyob rau hauv daim ntawv foos ntsiav tshuaj, qhov nquag ua haujlwm ntawm cov uas muaj tib lub npe. Cov tshuaj ntxiv ntawm cov tshuaj yog lactose monohydrate, hmoov txhuv nplej siab, cellulose, magnesium stearate, butylhydroxyanisole, citric thiab ascorbic acid.

Ib hom tshuaj yuav muag tsuas yog thaum tus neeg muaj ntawv nqa tshuaj los ntawm nws. Thaum nriav cov tshuaj, tus neeg mob yuav tsum them sai sai rau daim ntawv txuas nrog. Cov kev qhia muaj ntau tus lej ntawm kev qhia siv rau cov tshuaj no:

kev kho mob ntawm thawj hypercholisterinemia ua ke hom IIa thiab IIb,
kev kho hyperlipoproteinemia (txoj kev mob ntshav qab zib thiab mob nephrotic),
kev kho mob ntawm txoj hlab ntshav atherosclerosis (ua ke nrog kev kho vitamin thiab kev pabcuam tsis muaj roj fatty acids),
kev tiv thaiv cov hlab plawv pathologies,
hypertriglyceridemia kev kho mob.

Kev siv cov ntsiav tshuaj yuav tsum tau nqa tawm 1 zaug hauv ib hnub thaum noj hmo. Qhov ntau npaum ntawm cov tshuaj yog nyob ntawm tus kabmob. Yog li, nrog hyperlipidemia, ib koob tshuaj 10-80 mg yog tau xaj.

Kev kho kab mob pathology pib nrog kev txhaj tshuaj me me, nrog kev tso cai los ntawm tus kws kho mob, tuaj yeem maj mam nce ntxiv. Nws raug nquahu kom xaiv cov tshuaj nyob rau txhua 4 asthiv.

Qhov kev siv ntau tshaj (80 mg) tuaj yeem faib ua ob zaug tshuaj - thaum sawv ntxov thiab yav tsaus ntuj.

Hauv kev kho mob ntawm txoj hlab ntshav atherosclerosis, noj tshuaj zoo yog 20-40 mg. Yog tias kev kho mob tsis ua hauj lwm zoo, nce ntxiv txog 60-80 mg yog ua tau. Yog tias tus neeg mob noj cov tshuaj fibrates lossis nicotinic acid tib lub sijhawm, Lovastatin yuav tsum siv tsis tshaj 20 mg ib hnub. Tsis tas li, cov koob tshuaj yuav tsum tau txo hauv qhov xwm txheej zoo li no:

Kev siv tshuaj tiv thaiv kev tsis haum tshuaj.
Kev siv cov tshuaj tiv thaiv kab mob.
Kev kho nrog cov tshuaj tua kab mob.
Kev kho mob ntawm daim siab kab mob ntawm ib qho tshwj xeeb lossis dav dav etiology.
Siv cov tshuaj muaj anticoagulants.

Nws yog ib qho tsim nyog yuav tsum khaws cov tshuaj ntawm qhov kub tsis tshaj 25 degrees Celsius.

Tom qab hnub tas sijhawm, uas yog 2 xyoos, nws tau txwv tsis pub siv cov khoom.

Cov kev thaiv tsis zoo thiab cov tshwm sim

Lovastatin muaj cov npe me me ntawm cov lus pov thawj contraindications. Kev siv cov tshuaj yog txwv tsis pub myopathy (mob neuromuscular mob), cev xeeb tub, cholestasis, mob siab rau lub siab, qis dua 18 xyoo thiab tus neeg mob siab rau lub Cheebtsam.

Cov tshuaj yuav tsum tau siv nrog ceev faj nyob rau hauv cov neeg mob uas tau underonone coronary artery bypass grafting. Nyob rau hauv tsis muaj qee yam yuav tsum tau koj noj tshuaj nrog dej cawv.

Muaj qee kis, noj tshuaj muaj peev xwm ua rau muaj kev mob tshwm sim. Ntawm lawv, nws yog ib qhov tsim nyog los tseem ceeb:

Cov tshuaj tiv thaiv cuam tshuam nrog kev ua haujlwm ntawm lub plab zom mov: tawm tsam xeev siab, kub siab, txhim kho roj tsim, hloov pauv ntawm saj, raws plab, hloov quav.
Kev tsis ncaj ncees ntawm lub hauv nruab nrab cov hlab ntsha: mob taub hau, pw tsaug zog tsis zoo, ntxhov siab, kiv taub hau, txha caj dab, mob leeg nqaij, mob leeg thiab myalgia. Thaum siv cyclosporine, gemfibrozil lossis nicotinic acid, muaj qhov ua tau ntawm rhabdomyolysis.
Cov tshuaj tiv thaiv ntawm biliary system: nce kev ua haujlwm ntawm bilirubin, alkaline phosphatase, daim siab hloov pauv thiab creatine phosphokinase. Qee zaum muaj kab mob siab, mob cholestatic jaundice thiab chilestasis biliary muaj peev xwm ua tau.
Ua xua: khaus, tawv nqaij ua pob, urticaria, angioedema, mob pob txaws.
Kev cuam tshuam ntawm pob muag daj: atrophy ntawm optic hlab ntsha thiab kev loj hlob ntawm cataracts.
Lwm cov kev mob tshwm sim: txo qis potency, dav dav tshwm sim, alopecia.

Cov tsos mob ntawm kev haus ib qho zuj zus thaum siv loj ntawm cov tshuaj tsis pom. Lub hauv paus ntawm txoj kev kho yog tshem tawm Lovastatin, mob plab, kev siv cov kev ua kom vwm (ua kom cov pa roj carbon, Smecta, Polysorb, Atoxil) tswj cov haujlwm tseem ceeb, lub siab ua haujlwm thiab creatine phosphokinase.

Sib cuam tshuam nrog lwm txoj kev

Lovastatin yuav tsum tsis txhob siv nrog txhua cov tshuaj, vim lawv kev sib cuam tshuam yuav ua rau muaj kev tsis zoo ntawm lub cev. Ntxiv mus, qee cov tshuaj tuaj yeem nce qhov siab ntxiv ntawm cov tshuaj nquag, thiab qee qhov tuaj yeem txo qis.

Ib qho kev pheej hmoo siab ntawm cov leeg mob rhuav tshem thiab myopathy, nrog rau kev nce ntxiv hauv cov ntsiab lus ntawm cov khoom xyaw, ua rau tib lub sijhawm muaj kev siv Lovastatin nrog rau cov nicotinic acid, Cyclosporine, Ritonavir, Erythromycin, Nefazodone thiab Clarithromycin.

Kev siv ntau ntawm cov tshuaj nrog cov kua txiv kab ntxwv qaub, fenofibrate, gemfibrozil kuj tseem muaj feem ntau rau txoj kev myopathy.

Kev pheej hmoo ntshav los ntau ntxiv nrog rau kev siv tshuaj warfarin. Lub bioavailability ntawm lovastatin yog txo thaum siv colestyramine. Txhawm rau kom cov bioavailability ntawm cov tshuaj nyob hauv lub cev, nws yuav tsum tau siv cov tshuaj nrog kev ncua sij hawm ntawm 2-4 teev.

Nrog rau cov kab mob sib xyaw, tus neeg mob yuav tsum tau sab laj nrog kws kho mob txog kev noj tshuaj.

Qee ntawm lawv tsis cuam tshuam nrog Lovastatin, yog li ntawd, kev ywj pheej siv cov tshuaj yog nruj me ntsis txwv tsis pub.

Tus nqi, analogues thiab kuaj xyuas neeg mob

Hmoov tsis zoo, tam sim no nws tsis muaj peev xwm yuav Lovastatin vim tias Nws tsis yog tsim nyob rau hauv Russia.

Cov chaw muag tshuaj xws li Lekpharm (Belarus), Replekpharm AD (Macedonia) thiab Kievmedpreparat (Ukraine) yog cov tsim tshuaj.

Hauv qhov no, tus kws kho mob tuaj yeem sau tshuaj ib qho sib piv ntawm Lovastatin, uas muaj tib yam kev kho mob.

Cov tshuaj uas nrov tshaj plaws yog:

Holetar. Nws muaj cov tshuaj tivthaiv uas nquag ua haujlwm - lovastatin, yog li ntawd nws yog lus rau Lovastatin. Cov tshuaj muaj tib qho taw qhia, contraindications thiab phiv tshuaj li Lovastatin.
Cardiostatin. Lwm qhov zoo-paub tshuaj yog lus zoo rau Lovastatin, vim hais tias muaj cov khoom xyaw ua si tib yam. Thaum noj Cardiostatin, cov lus tshaj tawm txoj kev kho tau pom zoo rau ob lub lis piam, thiab qhov siab tshaj plaws tom qab 4-6 lub lim tiam ntawm kev noj tshuaj. Tus nqi nruab nrab yog 290 rubles (hauv ib pob ntawm 30 ntsiav tshuaj ntawm 20 mg).
Pravastatin. Nws muaj qhov kev ua dav dav. Tus nquag ua hauj lwm yog pravastatinum. Cov tshuaj yog siv rau cov thawj hypercholesterolemia thiab sib xyaw dyslipidemia, nrog rau kev tiv thaiv ntawm ischemic mob plawv. Kev siv cov Pravastatin yog ua tau raws li kev tiv thaiv kab mob thib ob rau myocardial infarction, angina pectoris thiab post-hloov hyperlipidemia.
Zokor. Cov tshuaj nquag ua haujlwm ntawm tshuaj yog simvastatin. Lub ntsiab tseem ceeb ntawm cov tshuaj yog kho hypercholesterolemia. Zokor tseem tseem siv los ua pov thawj tus kheej los tiv thaiv kev txhim kho cov hlab plawv pathologies. Tus nqi nruab nrab yog 380 rubles (28 ntsiav tshuaj ntawm 10 mg) thiab 690 rubles (28 ntsiav tshuaj ntawm 20 mg).

Raws li Vyshkovsky Index, cov thawj coj hauv kev lag luam tshuaj Lavxias yog Cardiostatin, Mevacor, Holetar thiab Rovacor.

Cov lus taw qhia ntawm Lovastatin, ob leeg los ntawm cov neeg mob thiab los ntawm cov kws kho mob, yog qhov zoo. Cov tshuaj yog qhov muaj kev nyab xeeb thiab zoo rau cov neeg mob, txawm tias siv ntev.

Cov tshuaj tiv thaiv cuam tshuam nrog dyspeptic cuam tshuam qee zaum tshwm sim thaum pib ntawm txoj kev kho. Tom qab ob lub lim tiam, thaum lub cev tau siv los cuam tshuam ntawm cov nquag ua haujlwm, cov tsos mob nres. Qee zaum, cov theem ntawm ALT thiab AST nce, yog li nws yog qhov tsim nyog los tswj lawv cov ntsiab lus.

Tom qab 1.5 hli txij li hnub pib ntawm txoj kev kho, kev kuaj mob soj qab taug kev. Raws li txoj cai, muaj tus cwj pwm zoo hauv kev tshuaj ntsuam, i.e. lipid concentration yog txo qis.

Yuav ua li cas rau cov roj (cholesterol) tsawg yog tau piav nyob hauv cov yeeb yaj kiab hauv tsab xov xwm no.

Qhia koj qab zib lossis xaiv tus tub los ntxhais rau cov lus pom zoo. Nrhiav tsis pom. Nrhiav. Nrhiav tsis pom. Pom. Nrhiav tsis pom.

Tso tawm daim ntawv thiab muaj pes tsawg leeg

Daim ntawv ntau npaum li cas ntawm Lovastatin tso tawm yog cov ntsiav tshuaj: ib lub voj voos kheej kheej, dawb nrog lub ntsej muag daj, nrog lub ntsej muag (hauv cov duab los qhia ib pob 1-3 contour cell pob ntawm 10, 15 lossis 20 ntsiav tshuaj txhua).

Composition 1 ntsiav tshuaj:

cov tshuaj nquag: lovastatin - 20 lossis 40 mg (hauv qhov tseeb 100% qhuav teeb meem),
Cov khoom ua haujlwm pabcuam: colloidal silicon dioxide, magnesium stearate, pob kws nplej siab, butylhydroxyanisole, microcrystalline cellulose, qab zib mis.

Cov Tshuaj Hauv Tshuaj

Lovastatin yog ib qho inhibitor ntawm cov roj (endogenous cholesterol) synthesis hauv lub siab. Cov tshuaj hauv lub cev ua rau lub cev tsis muaj zog lactone ncaj qha rau hydrolyzed rau cov tshuaj tiv thaiv kev ua kom nquag plias, uas ua raws li kev sib tw inhibitor ntawm 3-hydroxy-3-methylglutaryl-coenzyme-A reductase (HMG-CoA reductase). Qhov no yog ib qho enzyme uas catalyzes hloov dua siab tshiab ntawm HMG-CoA rau mevalonate, uas yog thawj kauj ruam hauv cov roj ntsha biosynthesis.

Lub ntsiab cuam tshuam ntawm lovastatin:

txo hauv tag nrho cov roj hauv cov ntshav thiab cov roj (cholesterol) hauv LDL thiab VLDL (lipoproteins uas tsis muaj roj thiab lipoproteins tsawg tsawg),
kev ua kom tsis muaj zog ntawm qhov txo qis hauv cov ntsiab lus ntawm apolipoprotein B, qhov kev txiav txim ntawm triglycerides hauv ntshav ntshav thiab nce qib hauv cov concentration ntawm HDL (siab ceev lipoproteins),
plaque stabilization, txhim kho kev ua haujlwm ntawm endothelial, antithrombogenic thiab anti-inflammatory nyhuv (ua rau muaj txiaj ntsig antiatherosclerotic).

Cov tshaj tawm kev kho mob ntawm lovastatin tshwm sim tsis pub dhau 14 hnub, thiab qhov siab tshaj plaws tom qab 1-1.5 lub hlis ntawm kev tswj hwm zoo. Nyob rau tib lub sijhawm tom qab tsis ua tiav ntawm kev kho, cov nyhuv mob tsawv. Nrog lub sijhawm siv ntev (txog 5 xyoos), qhov zoo ntawm lovastatin tsis txo.

Cov Tshuaj Pharmacokinetics

Lovastatin yog nqus rau hauv plab zom mov (lub plab zom mov) maj mam thiab ua tsis tiav - txog 30% ntawm koob tshuaj. Thaum noj ntawm lub plab khoob, qhov nqus tau yog txo los ntawm 1/3 piv nrog siv nrog zaub mov.

Tmax (lub sijhawm kom mus txog qhov siab tshaj plaws) thaj tsam li 2 mus rau 4 teev, Cmax (qhov siab tshaj plaws) yog 7.8 thiab 11.9 ng / ml (rau lovastatin thiab beta-hydroxyacids), tom qab ntawd lub plasma concentration sai dua. Tom qab 24 teev, nws yog 10% ntawm qhov siab tshaj plaws. Kev sib txuas lus nrog cov ntshav plasma protein - 95%. Nrog tib lub koob tshuaj thaum hmo ntuj, kev tshem tawm ntawm lovastatin thiab nws cov tshuaj tiv thaiv nquag tau mus txog tom qab 48–72 teev.

Nkag tau los ntawm cov ntshav-lub hlwb thiab placental teeb meem.

Thaum dhau los ntawm daim siab thawj zaug, lovastatin undergoes introgen metabolism hauv, oxidizes rau beta-hydroxy acid, nws 6-hydroxy derivative thiab lwm yam khoom siv tiv thaiv kab mob, qee qhov ntawm cov pov thawj nthuav qhia kev ua haujlwm (lawv thaiv HMG-CoA reductase). Cov isoenzymes ntawm CYP3A4, CYP3A7 thiab CYP3A5 tau koom tes hauv cov metabolism hauv lovastatin.

T_1/2 (ib nrab-lub neej) yog 3 teev. 83% ntawm qhov koob tshuaj tau tawm ntawm txoj hnyuv, 10% - los ntawm ob lub raum.

Kev ntsuas rau siv

ua kom cov ntshav ntau dhau ntawm tag nrho cov roj (cholesterol), LDL cov roj (cholesterol) thiab triglycerides nyob rau hauv cov ntshav ntshav hauv cov neeg mob uas muaj tus mob hypercholesterolemia: lwm yam kev ntsuas tsis siv tshuaj
atherosclerosis rau cov neeg mob plawv (mob plawv): kho yog ua kom qeeb nws muaj mob.

Hyperlipidemia

Qhov pom zoo txhua hnub koob tshuaj Lovastatin yog 10-80 mg ib hnub ib zaug.

Hauv cov neeg mob uas muaj hypercholesterolemia muaj mob me me, lub koob tshuaj thawj zaug feem ntau yog 20 mg ib hnub ib hnub nyob rau yav tsaus ntuj, nrog qhov kev qhia tseeb ntawm tus kabmob (ntshav tag nrho cov roj hauv cov ntshav - los ntawm 7.8 mmol / l) - 40 mg. Txhawm rau kom ua tiav cov roj (cholesterol) hauv cov phiaj, qhov tshuaj yuav raug nce ntxiv rau 80 mg (siab kawg) hauv ib lossis ntau koob (sawv ntxov thiab yav tsaus ntuj).

Hloov cov koob tshuaj nrog kev cuam tshuam rau tsawg kawg 4 lub lis piam. Yog tias qhov theem siab ntawm tag nrho cov roj (cholesterol) hauv cov ntshav ntshav tau poob qis mus rau 140 mg / 100 ml lossis LDL roj cholesterol mus rau 75 mg / 100 ml, cov koob tshuaj Lovastatin tuaj yeem txo qis. Thaum ua ke nrog cyclosporine, fibrates lossis nicotinic acid (los ntawm 1000 mg ib hnub twg), qhov tshuaj yuav tsum tsis pub tshaj 20 mg ib hnub. Hauv cov neeg mob uas mob raum tsis zoo nrog creatinine kev tshem tawm tsawg dua 30 ml / min, cov tshuaj yog tshuaj hauv kev saib xyuas kev kho mob (ntau kawg koob - 20 mg ib hnub).

Lovasterol - cov lus qhia rau kev siv

Peb cov neeg nyeem tau siv Aterol ua tiav kom qis cov roj (cholesterol). Pom qhov nrov ntawm cov khoom no, peb tau txiav txim siab muab nws rau koj kom txaus siab.

Ntawm nplooj ntawv no: qhov kev piav qhia ntawm cov tshuaj Lovasterol, tag nrho cov kev mob tshwm sim, contraindications thiab cov lus qhia rau kev siv tshuaj Lovasterol raug txiav txim siab.

Lub npe thoob ntiaj teb uas tsis yog tus tswv ntawm cov tshuaj yeeb tshuaj yog cov lus qhia tseem ceeb txog kev siv tshuaj yaj yeeb. Qhov tseeb yog tias, raws li txoj cai, tshuaj nrog tib yam tshuaj muaj nyob hauv qab cov npe sib txawv, uas yog, qhov tseeb, qhov no yog tib yam tshuaj, tab sis tsim los ntawm cov tuam txhab sib txawv. Nws yog INN uas ua rau cov kws kho mob xaiv cov cuab yeej zoo los ntawm cov tshuaj muaj ntau nyob rau ntawm cov kws tshuaj yuav tom khw.

Daim ntawv tso tawm:

Ntsiav tshuaj
1 tab
lovastatin
20 mg
10 Pcs. - blister packs (3) - pob ntawv ntawm cardboard.

Ntsiav tshuaj
1 tab
lovastatin
10 mg
10 Pcs. - blister packs (3) - pob ntawv ntawm cardboard.

Ntsiav tshuaj
1 tab
lovastatin
40 mg
10 Pcs. - blister packs (3) - pob ntawv ntawm cardboard.

tab. 20 mg: 30 pcs.

tab. 10 mg: 30 pcs.

tab. 40 mg: 30 pcs.

Cerebrovascular disease: daim ntawv, ua rau, tshwm sim, tsos mob, yuav kho li cas

Cerebrovascular kab mob (CVB) yog lub pathology ntawm cov hlab ntsha hlwb, ua rau ischemia, hypoxia thiab ua txhaum ntawm ntau lub cev ua haujlwm. Hauv qab ntawm cov txiaj ntsig tsis zoo thiab dhau ntawm qhov muaj peev xwm, cov hlab ntsha hauv lub hlwb tau puas lawm, thiab lub hlwb kev puas hlwb yog cuam tshuam.

Cerebrovascular tus kab mob ua rau txoj kev loj hlob ntawm lub caj pas discirculatory encephalopathy - tus kab mob uas yog hloov kho cov hlwb pob txha caj dab hauv lub cev los ntawm kev mob ntsws tsis txaus. Cov kab mob no yav dhau los suav hais tias yog teeb meem ntawm cov neeg laus. Tam sim no, cerebrovascular tsis txaus "hluas dua": tus kab mob no nce ntxiv rau hauv cov neeg muaj hnub nyoog qis dua 40 xyoo. Qhov no yog vim muaj kev ua neej tsis zoo, kev noj kev haus tsis zoo, kev noj haus tsis zoo.

Cerebrovascular kab mob yog tam sim no muaj teeb meem kev kho mob tseem ceeb. Nws nyob rau qib thib peb hauv tus qauv ntawm tag nrho cov kev tuag tom qab mob plawv thiab mob paj hlwb. CVI yog qhov ua rau muaj mob stroke thiab cov neeg xiam oob khab ntev.

Kev faib tawm

Cerebrovascular kab mob - kab mob ntawm cov ntshav ncig, uas suav nrog:

Hemorrhagic thiab ischemic sib ntaus.
Ntev discirculatory pathology ntawm lub paj hlwb - occlusion thiab vasospasm, arteritis, aneurysm.
Intracranial hemorrhage.
Kub siab cerebrovascular kab mob - atherosclerotic thiab kub siab encephalopathy.

Lub ntsiab etiological ntawm tus kab mob:

Atherosclerotic qhov chaw mob ntawm cov hlab ntsha ua rau lub hauv paus ntawm cov cholesterol, qhov tsim ntawm cov quav, lawv nqaim thiab txhaws, thiab tom qab ntawd ua txhaum kev ua txhaum ntawm cov ntshav hlwb, trophic lub hlwb thiab cov txheej txheem hlwb.
Kev ua haujlwm ntawm cov ntshav coagulation system, thrombosis thiab thromboembolism feem ntau ua rau muaj kev cuam tshuam ntawm lub hlwb microcirculation.
Spasm ntawm cov hlab ntsa phab ntsa nyob rau hauv muaj cov mob ntshav siab ua kom tsis txhob cerebral ntshav txaus.
Vasculitis cuam tshuam txoj kev xa ntshav mus rau lub hlwb.
Osteochondrosis tuaj yeem ua rau vertebro-basilar tsis txaus thiab kev hloov pauv ntawm cov hlab ntsha khiav lag luam.

Koom xwm provoking kev loj hlob ntawm pathology:

Peb cov neeg nyeem tau siv Aterol ua tiav kom qis cov roj (cholesterol). Pom qhov nrov ntawm cov khoom no, peb tau txiav txim siab muab nws rau koj kom txaus siab.

Mob ntshav qab zib mellitus
Laus lub caij nyoog
Hypercholesterolemia, dyslipidemia,
Kev pham
Tawg siab
Ischemic mob plawv,
Kev ntxhov siab
Mob puas hlwb
Lub caij nyoog siv ntawm lub qhov ncauj txwv tsis pub rho tawm,
Haus Yeeb
Sedentary lub neej
Neeg muaj keeb.

Symptomatology

Cerebrovascular kab mob thaum pib theem ntawm nws txoj kev loj hlob yog pom los ntawm cov tsos mob hauv qab no:

Tsawg dua kev ua haujlwm, ua kom qaug zog,
Kev voos npau taws, ua haujlwm tsis zoo, qhov kev xav tsis txaus,
Hauv fussiness dhau
Insomnia
Tsaus ntuj li tshav kub
Lub qhov ncauj qhuav
Ntxoov Huaj
Lub plawv palpitations.

Yav tom ntej, raws li lub hlwb hypoxia nce, cov xwm txheej txaus ntshai tshwm sim thiab cov cim loj dua tshwm sim: kev tsis muaj peev xwm ua kom pom tseeb, tsis hnov qab, tsis nco qab, tsis pom kev, ua kom sib haum, tsis muaj mob taub hau, txo lub hlwb.

Hauv cov neeg mob, kev nyuaj siab tshwm sim, kev txawj ntse poob qis, neuroses thiab lub hlwb tawg, phobias thiab kev ntshai, egocentrism, tawg, qhov muag tsis muaj zog. Cov neeg mob ua hypochondriacal thiab tsis nyab xeeb. Thaum muaj mob hnyav, ua tsis taus pa, tshee tshee, gait tshee, tsis hnov lus, txav tau thiab rhiab ntawm qhov mob tseem ceeb, lub cev tsis nco qab ploj, thiab cov plab hnyuv siab raum ntawm lub zeem muag cuam tshuam.

Ib qho kev nce ntxiv ntawm morphological kev hloov pauv hauv lub hlwb ua rau cov tsos ntawm ntau cov lus tshaj tawm thiab pom tau - ua rau lub hlwb tawg thiab cov hlab ntsha tawg, paresis thiab tuag tes tuag taw, txha caj qaum, mob plab tsis txaus, ua kom lub suab luag thiab quaj.

Cov cim no tau tshwm sim hauv cov neeg mob thoob plaws ib hnub qhia tias muaj kev ua txhaum ntau ntawm cov hlab hlwb - cerebrovascular mob stroke. Yog tias lawv ploj nyob rau lub sijhawm luv, kev xav tias tsis muaj islamic nres yog xav tau.

3 qib ntawm cov hlab ntsha tsis zoo sib xws:

CVB ntawm thawj degree tau tsis pom muaj neeg coob. Nws cov tsos mob muaj ntau txoj hauv kev zoo ib yam li cov tsos mob ntawm lwm yam kab mob lossis kev raug mob.
Qhov kev kawm ntawv thib ob yog pom los ntawm kev puas siab puas ntsws. Tus kabmob yog qhia rau kev kho tus mob xiam oob qhab, tab sis tus neeg mob pabcuam nws tus kheej.
Qeb peb yog kev hloov pauv ntawm pathology rau lub sijhawm ntawm vascular dementia. Tus neeg mob tsis tuaj yeem txav mus los thiab hauv thaj chaw; nws xav tau kev pab thiab saib xyuas cov neeg nyob ib puag ncig nws. Cov cwj pwm ntawm cov neeg mob zoo li no yuav tsum raug tswj.

Cov teeb meem feem ntau ntawm CVB yog: mob stroke, hloov ischemic nres, dementia, cerebrovascular tsis nco qab lawm.

Kev kuaj mob

Kev kuaj mob thiab kev kho mob ntawm cerebrovascular pathology koom nrog neuropathologist thiab vascular phais. Lawv xaiv cov txheej txheem kev kho mob kom raws li cov yam ntxwv ntawm qhov kev kawm ntawm tus kab mob, qhov xwm txheej dav dav ntawm tus neeg mob thiab muaj mob tsis zoo.

Kev tshuaj xyuas dav dav ntawm cov neeg mob CVI suav nrog:

Soj ntsuam kev kuaj ntshav
Qhia txog ntshav ntshav
Kev txiav txim siab ntawm prothrombin Performance index,
Cov tshuaj tiv thaiv kab mob syphilis,
ECG
Mob Lub Hlaus
Kev ntsuas hluav taws xob xoo.

Cov hau kev npaj rau kev ua tiav thiab kev qhia paub ntawm cov kab mob cerebrovascular:

Duplex lossis triplex angioscanning yog npaj rau thawj qhov mob ntawm CVB. Nws yog kev nyab xeeb, sai thiab pheej yig tshaj. Ua li no, cov hlab ntsha cuam tshuam tuaj yeem kuaj xyuas ntau zaus thiab tsis muaj kev phom sij rau kev noj qab haus huv.
Angiography yog ib txoj kev sib piv los ntawm kev ntsuas xoo hluav taws xob ntawm cov hlab ntsha, uas tso cai txiav txim siab rau lawv lub xeev kev ua haujlwm, muaj cov txheej txheem pathological thiab nws ntev. Cerebral angiography tau ua tom qab kev saib xyuas ntawm tus neeg sawv cev sib piv rau hauv cov ntshav. Nws tso cai rau tus neeg mob los txiav txim siab qhov muaj mob ntawm thrombosis, atherosclerotic lesions thiab vasoconstriction, oncopathology, hematoma thiab aneurysm.
Lub hlwb scintigraphy yog ib txoj kev tshawb fawb yooj yim thiab tsis muaj kev cuam tshuam uas tsis muaj qhov tsis muaj qhov sib txuam nrog thiab tsis ua rau muaj teeb meem. Nuclear scanning yog ib txoj kev nkag siab zoo thiab siv tau cov ntsiab lus los kuaj mob cerebrovascular. Qhov tshuaj yeeb yaj kiab hluav taws xob yog txhaj rau hauv txoj hlab ntshav, thiab tom qab 15 feeb tsom iav tau. Lub sijhawm no yog txaus rau cov radioisotope kis mus rau thoob plaws lub cev thiab nthuav tawm hauv cov ntaub so ntswg uas kho pathologically. Qhov ntsuas muaj cov koob tshuaj tiv thaiv hluav taws xob uas tsis ua kom puas rau lub cev.
Transcranial Doppler ultrasound yog kev xoo ntawm lub cerebral cov hlab ntsha uas ntsuas cov ntshav khiav ceev thiab nthuav tawm cov ntshav hemodynamic tsis meej.
Ntawm tsis muaj qhov tseem ceeb me me hauv kev kuaj mob ntawm CVB yog MRI thiab CT.

Nws yog tsis yooj yim sua kom pom tseeb thiab kho kab mob cerebrovascular. Tsuas yog tus kws paub dhau los, cov kws tshaj lij, tau kawm tus neeg mob cov lus tsis txaus siab thiab tau kuaj nws tiav, yuav tshaj tawm txoj kev kho mob uas tsim nyog. Txoj kev kho kom tsim nyog thiab raws sijhawm yuav txhim kho lub neej kev mob ntawm tus neeg mob thiab txo qhov kev pheej hmoo ntawm kev tsim lub neej muaj sia - mob stroke.

Lub hom phiaj tseem ceeb ntawm kev kho mob yog kev tshem tawm kev cuam tshuam ntawm lub hlwb kev ua haujlwm. Txhawm rau kom ua tiav ntawm cerebrovascular pathology, nws yog qhov tsim nyog los txiav txim siab thiab tshem tawm nws qhov ua rau. Ntxiv rau kev sau tshuaj noj, cov kws tshwj xeeb tau muab cov lus tseem ceeb rau cov neeg mob: hloov lawv lub neej, yuag, tsis haus luam yeeb lossis haus dej haus cawv, noj kom raug thiab tsim nyog.

Tshuaj kho mob nkeeg

Kev kho mob ntawm cerebrovascular feem ntau tau ua nyob rau hauv lub tuam tsev neurological. Cov kws kho mob tshwj xeeb feem ntau tshem tawm cov kev pheej hmoo: sau tshuaj rau antisclerotic, hypotensive, hypoglycemic tshuaj. Tsuas yog tom qab kho kho ntawm cov metabolism hauv lub ntsiab lawv mus rau kev kho mob ncaj qha ntawm pathology.

Kev kho tshwj xeeb

Cov pab pawg tseem ceeb ntawm cov tshuaj uas txhim kho cov kev mob hlwb thiab npaj rau kev kho mob ntawm cerebrovascular tsis txaus:

Cov calcium calcium blockers txhim kho cerebral ntshav txaus, qis mem tes ceev, inhibit platelet cohesion thiab txhim kho cov ntshav sib xyaw. Cov tshuaj raws li nifedipine dilate cov hlab ntsha ntawm lub paj hlwb - Corinfar, Kardipin, cov tshuaj los ntawm cov pab pawg diltiazem Dilzem, Kardil. Cinnarizine thiab nws cov derivatives, Verapamil, kuj zwm rau calcium channel blockers.
Antioxidants. Cov tshuaj muaj zog tiv thaiv tau rau cov kab mob cerebrovascular, mob stroke thiab encephalopathy yog Cerebrolysin. Ntxiv rau nws, Cerebrocurin thiab Actovegin feem ntau siv.
Antihypoxants raug kho rau cov kab mob cerebrovascular - Ketoprofen, Imidazole, Mekaprin.
Metabolics - "Cavinton", "Sermion", "Vinpocetine", "Tanakan".
Cov tshuaj tiv thaiv ncaj qha - “Heparin”, “Fraxiparin” thiab ncaj qha - “Phenilin”, “Sincumar”, “Warfarin”.
Antiplatelet Kev Kho Mob - "Acetylsalicylic acid", "Curantyl".
Cov tshuaj nrog hypocholesterolemic kev txiav txim, statins - "Lovastatin", "Lipostat", "Probucol", "Tykveol".
Cov tshuaj Nootropic - Omaron, Piracetam, Pantogam, Glycine, Phenibut.
Tshuaj kho mob uas txhaws cov hlab ntsha ntawm lub hlwb - Pentoxifylline, Trental, Agapurin.
Antispasmodics - "Papaverine", "Eufillin", "Dibazol."

Kev kho mob tseem ceeb

Cov kev kho mob yooj yim ntawm CVB yog kev ib txwm ua haujlwm ntawm kev ua pa ntawm sab nraud, txoj hlab plawv, tswj kev ua haujlwm hauv lub cev, thiab neuroprotection.

Txhawm rau ua qhov no, cov hlab pas tau tsau tshuaj, lub raj cua ua pa tawm, thiab lub qhov txhab ua pa nqus tau ua.
PThaum cov tsos mob ntawm lub plawv tsis ua haujlwm thiab mob ntsws ntsws tshwm sim, "Lasix" thiab "Pentamine" yog siv.
Antiarrhythmic txoj kev kho yog qhia rau cov neeg mob plawv dhia tsis txaus. Feem ntau siv cov tshuaj antianginal, mob glycosides - Strofantin, Korglikon, tshuaj tua kab mob antioxidant.
"Seduxen", "Haloperidol", "Diphenhydramine", "Sodium oxybutyrate" yuav pab ua kom tsis txhob muaj zaub ntau.
Txhawm rau tawm tsam mob txha caj qaum, osmotic diuretics siv - Mannitol, Furosemide.
Txhawm rau tswj cov ntshav siab, Atenolol, Enalapril, Nifedipine, Dibazol tau sau tseg.
Kev kho cov teeb meem metabolic yog ua tiav los ntawm kev rov ua tiav cov kua txig ntxiv nrog cov kev daws teeb meem ntawm Ringer, ntshav, qabzib.
Kev kho mob tshwm sim suav nrog kev siv tshuaj anticonvulsant thiab psychotropic, cov leeg ua kom mob, cov leeg ua pob - "Analgin", "Ketorol", "Promedol".

Hyperbaric oxygenation yog cov txheej txheem kho lub cev ua haujlwm uas muab cov ntshav oxygen thiab nws cov nkag mus rau hauv cov nqaij cuam tshuam rau lub hlwb. Tus neeg mob yog nyob rau hauv chav tshwj xeeb thiab nqus pa ntshiab. Hyperbaric oxygenation tshem tawm cov pa oxygen cov nuj nqis ntawm cov ntaub so ntswg thiab rov qab aerobic glycolysis. Cov txheej txheem no txhim kho lub neej zoo ntawm cov neeg mob, txo cov tsos mob ntawm tus kab mob thiab tiv thaiv kev txhim kho ntawm cov kev mob hnyav.

Kev phais mob

Cov qauv mob hnyav, tsis zoo rau kev kho mob, kom muaj kev phais mob. Cov neeg mob raug tshem tawm cov ntshav txhaws thiab atherosclerotic plaques los ntawm cov hlab ntsha, nce lumen ntawm cov hlab ntsha siv cov raj thiab pob, thiab stents yog tso rau hauv cov hlab ntsha uas tswj lub lumen ntawm lub nkoj qhib.

Cerebrovascular cov kab mob yog raug rau kev phais mob: txoj hlab ntshav pob txha leeg ntshav thiab mob ntshav hauv tsev.

Pej xeem noj tshuaj

Cov tshuaj ib txwm siv hauv kev kho mob cerebrovascular:

Lub hauv paus peony yog qhuav, hauv av thiab hliv nrog dej npau. Tso cov tshuaj no rau ib teev, lim thiab noj 5 zaug ib hnub rau ib diav.
2 txiv kab ntxwv thiab 2 lub txiv qaub muaj lub ntsej muag sib tsoo rau hauv cov nqaij grinder, qhov ntau yog nrog kua zib mu ua kua thiab sib xyaw. Txheeb rau hnub txias, thiab tom qab ntawd nqa ib diav 3 zaug hauv ib hnub.
Coniferous koob yog hliv nrog dej npau, ntxig thiab ntxiv cov kua txiv ntawm ib nrab ntawm lub txiv qaub rau ua kua. Siv cov tshuaj ntawm cov npliag plab rau 3 lub hlis.
Celandine tincture tau noj ntawm lub plab khoob peb zaug ib hnub twg rau 2 lub lis piam.

Tsoos tshuaj yog qhov zoo ntxiv rau cov kev kho mob tseem ceeb ntawm pathology.

Kev tiv thaiv thiab kev kwv yees

Kev ntsuas los tiv thaiv kev txhim kho ntawm cerebrovascular:

Kev kho ntshav siab
Kev kho mob kom raws sijhawm,
Ntaus tus cwj pwm tsis zoo
Kev tawm dag zog lub teeb
Cov khoom noj kom zoo
Kev ua haujlwm zoo thiab so
Kev hloov kho qhov hnyav.

Txog lub hom phiaj prophylactic, cov neeg mob tau sau tshuaj uas txhim kho cov mob hlwb thiab tua ntshav coagulation.

Yog tias tus kabmob muaj kev kho mob tau raws sijhawm thiab kho kom raug, nws muaj peev xwm ua tsis tau tsuas yog txhim kho lub neej ntawm tus neeg mob, tabsis tseem yuav txo tau txoj kev pheej hmoo ntawm mob stroke thiab lwm yam kev mob nyhav.