Insulin Actrapid: tus nqi thiab cov lus qhia rau kev siv
Cov tsoos txhais tau tias ntawm kev txo cov piam thaj tom qab noj mov suav nrog luv luv ua haujlwm rau tib neeg insulins. Ib qho tshuaj uas nrov tshaj plaws, Actrapid, tau tawm tsam ntshav qab zib ntau dua 3 xyoo lawm. Tau ntau xyoo, nws tau ua pov thawj tias nws cov khoom zoo thiab cawm ntau lab tus neeg lub neej.
Tam sim no, cov tshiab, txhim kho insulins twb muaj lawm uas muab cov glycemia li qub thiab pub dawb los ntawm qhov tsis zoo ntawm lawv cov neeg ua ntej. Dua li ntawm qhov no, Actrapid tsis muab nws txoj haujlwm thiab nquag siv kho mob ntshav qab zib hom 1 thiab ntshav qab zib hom 2.
Cov lus qhia luv luv rau kev siv
Actrapid yog ib qho ntawm thawj cov insulins tau los ntawm kev siv cov qauv hauv engineering. Nws tau tsim tawm rov qab rau xyoo 1982 los ntawm kev txhawj xeeb txog kev lag luam tshuaj Novo Nordisk, uas yog qhov loj tshaj plaws ntawm kev tsim cov tshuaj kho ntshav qab zib nyob hauv lub ntiaj teb. Lub sijhawm ntawd, cov neeg mob ntshav qab zib yuav tsum tau muaj cov ntsiab lus nrog tsiaj cov tshuaj insulin, uas muaj cov ntshav ua kom huv si thiab ua kom lub cev ua xua ntau dua.
Actrapid tau txais los ntawm kev siv cov hloov pauv, qhov khoom tiav tiav rov qab ua rau cov insulin tsim hauv tib neeg. Lub thev naus laus zis tso cai rau kom ua tiav qhov ua tau zoo hypoglycemic thiab siab purity ntawm kev daws, uas txo qhov kev pheej hmoo ntawm kev ua xua thiab kev ua rau ntawm thaj chaw txhaj tshuaj. Cov kab ntsuas (sau npe ntawm cov tshuaj tso npe los ntawm Ministry of Health) qhia tias cov tshuaj no tuaj yeem tsim thiab ntim hauv Denmark, Fabkis thiab Brazil. Kev tsim tawm kev tswj hwm yog nqa tawm tsuas yog nyob hauv Europe, yog li tsis muaj kev ntseeg siab txog qhov zoo ntawm cov tshuaj.
Cov lus qhia luv luv txog Actrapide los ntawm cov lus qhia rau kev siv, uas txhua tus kabmob ntshav qab zib yuav tsum paub txog:
Nkaus | Nws txhawb kev hloov pauv ntawm qab zib los ntawm ntshav mus rau cov ntaub so ntswg, txhim kho kev sib txuas ntawm glycogen, cov nqaijrog thiab rog. |
Muaj pes tsawg leeg |
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Cov Khoom Qhia |
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Cov Yuav Tsum Muaj | Cov tib neeg cov tshuaj tiv thaiv los ntawm cov tshuaj tiv thaiv kab mob uas tsis ploj rau 2 lub lim tiam txij li pib siv tshuaj insulin lossis tshwm sim hauv daim ntawv hnyav:
Actrapid txwv tsis pub siv rau hauv cov twj insulin, vim nws yog nquag rau crystallization thiab tuaj yeem txhaws qhov infusion system. |
Xaiv xaiv | Actrapid yog qhov tsim nyog los them rau cov ntshav qabzib uas nkag rau hauv cov hlab ntshav tom qab noj mov. Kev noj tshuaj ntau npaum li cas yog xam los ntawm cov khoom noj hauv carbohydrates muaj nyob hauv cov zaub mov. Koj tuaj yeem siv txheej txheej ntawm chav nyob qhob cij. Qhov ntim ntawm cov tshuaj insulin ntawm 1XE yog txiav txim siab los ntawm kev xam, ib tus lej coefficients raug kho raws li cov txiaj ntsig ntawm kev ntsuas glycemia. Qhov ntau npaum li cas yog qhov txiav txim siab yog tias cov piam thaj hauv ntshav rov qab mus rau nws qib qub tom qab qhov kawg ntawm qhov kev txiav txim ntawm Actrapid insulin. |
Qhov tsis txaus siab ua | |
Ua ke nrog lwm cov tshuaj | |
Cev xeeb tub thiab GV | Thaum cev xeeb tub thiab lactation Actrapid pub. Cov tshuaj tsis hla lub cev, yog li ntawd, nws tsis tuaj yeem cuam tshuam kev loj hlob ntawm tus me nyuam hauv plab. Nws kis mus rau cov kua mis hauv cov khoom me me, tom qab ntawd nws tau muab faib rau ntawm txoj hnyuv hauv lub plab. |
Actrapid insulin daim ntawv foos tso tawm | Radar suav nrog 3 daim ntawv ntawm cov tshuaj uas raug tso cai muag hauv tebchaws Russia:
Hauv kev coj ua, tsuas yog lam fwj (Actrapid NM) thiab cov cartridges (Actrapid NM Penfill) tau muag. Tag nrho cov foos muaj tib qho kev npaj ua nrog qhov kub siab ntawm 100 units ntawm insulin ib milliliter ntawm kev daws. |
Cia | Tom qab qhib, cov tshuaj insulin cia rau 6 lub lis piam hauv qhov chaw tsaus, qhov kub tso cai muaj txog 30 ° C. Kev ntim khoom seem yuav tsum yog nyob hauv tub yees. Txwv tsis pub siv tshuaj Actrapid insulin los khov. Saib ntawm no >> cov cai dav dav rau kev ntim tshuaj insulin. |
Actrapid yog ib xyoos ib zaug muaj nyob rau hauv daim ntawv teev cov tshuaj tseem ceeb, yog li cov neeg mob ntshav qab zib tuaj yeem tau txais nws dawb, nrog tshuaj los ntawm koj tus kws kho mob.
Cov Ntaub Ntawv Ntxiv
Actrapid NM yog hais txog luv luv (daim ntawv teev npe ntawm cov insulins luv luv), tab sis tsis yog cov tshuaj ultrashort. Nws pib ua tom qab 30 feeb, yog li ntawd lawv qhia nws ua ntej. Cov piam thaj los ntawm cov zaub mov uas muaj GI tsawg (piv txwv li, buckwheat nrog nqaij) tswj kom "ntes" cov insulin no thiab tshem tawm ntawm cov ntshav kom raws sijhawm. Nrog cov carbohydrates ceev ceev (piv txwv li, tshuaj yej nrog ncuav mog qab zib), Actrapid tsis muaj peev xwm tawm tsam sai sai, yog li tom qab noj zaub mov hyperglycemia yuav tshwm sim dhau los, uas yuav tom qab ntawd txo qis. Xws li cov ntshav qab zib tsis tsuas yog ua rau txoj kev noj qab haus huv zoo rau tus neeg mob, tab sis kuj tseem ua rau kev txhim kho ntawm kev mob ntshav qab zib. Txhawm rau kom qeeb ntawm txoj kev loj hlob ntawm glycemia, txhua pluas noj nrog Insulin Actrapid yuav tsum muaj fiber ntau, protein lossis rog.
Sijhawm ua
Actrapid ua haujlwm txog li 8 teev. Thawj 5 teev - qhov kev txiav txim tseem ceeb, tom qab ntawd - pom qhov seem. Yog tias cov tshuaj insulin raug tswj xyuas ntau zaus, cov nyhuv ntawm ob koob yuav rov qab ua ke. Nyob rau tib lub sijhawm, nws yuav luag tsis yooj yim los xam qhov xav tau ntau npaum li cas ntawm cov tshuaj, uas ua rau muaj kev pheej hmoo ntawm hypoglycemia. Txhawm rau kom siv cov tshuaj tiav, pluas noj thiab tshuaj insulin yuav tsum tau faib txhua 5 teev.
Cov tshuaj muaj qhov ua siab tshaj plaws tom qab 1.5-3.5 teev. Los ntawm lub sijhawm no, feem ntau ntawm cov zaub mov muaj sijhawm zom, yog li ua rau lub ntsej muag ntshav nce qis. Txhawm rau zam nws, koj xav tau khoom txom ncauj rau 1-2 XE. Hauv tag nrho, nrog ntshav qab zib mellitus ib hnub, 3 lub ntsiab thiab 3 cov zaub mov ntxiv tau txais.Kev siv tshuaj Insulin Actrapid tsuas yog muab ua ntej ua ntej nkaus xwb, tab sis nws txoj kev noj tshuaj yog xam los ntawm kev suav cov khoom noj txom ncauj.
Taw qhia cov kev cai
Vials nrog Actrapid NM tsuas yog siv tau nrog cov koob tshuaj insulin cov ntawv cim U-100. Cartridges - nrog cov koob txhaj tshuaj thiab cov xaum xaum: NovoPen 4 (ntsuas qhov ntsuas 1 ib lub tsev), NovoPen Echo (0.5 units).
Txhawm rau kom cov tshuaj insulin ua haujlwm nrog ntshav qab zib, koj yuav tsum kawm cov txheej txheem kev txhaj tshuaj hauv cov lus qhia rau kev siv thiab ua raws nraim. Feem ntau, Actrapid txhaj rau hauv qhov quav ntawm lub plab, daim ntaub nqus dej nyob ntawm kaum ntawm daim tawv nqaij. Tom qab nkag mus, rab koob tsis raug tshem tawm ob peb feeb kom tiv thaiv cov tshuaj los ntawm kev ntws tawm. Cov tshuaj insulin yuav tsum nyob ntawm chav sov. Ua ntej kev tswj hwm, nws yog ib qho tsim nyog yuav tsum kuaj xyuas lub hnub tim uas tas sij hawm thiab qhov tsos ntawm cov tshuaj.
Txwv tsis pub ib lub raj mis uas muaj cov xaum xaum, dej hauv av lossis iav ci hauv sab hauv.
Piv nrog rau lwm cov insulins
Txawm hais tias qhov tseeb tias Actrapid lwg me me yeej zoo ib yam rau tib neeg cov kua dej, lawv cov nyhuv txawv. Qhov no vim yog subcutaneous tswj hwm ntawm cov tshuaj. Nws xav tau sijhawm los tso cov ntaub so ntswg thiab ua kom muaj ntshav txaus. Tsis tas li ntawd, cov tshuaj insulin yog qhov txaus ntshai rau kev tsim cov qauv hauv cov ntaub so ntswg, uas tseem tiv thaiv cov suab thaj txo sai.
Tus kws kho mob ntawm Kev Tshawb Fawb Kev Kho Mob, Lub Taub Hau ntawm lub koom haum ntawm Diabetology - Tatyana Yakovleva
Kuv tau kawm qhov teeb meem mob ntshav qab zib tau ntau xyoo. Nws yog txaus ntshai thaum muaj coob tus neeg tuag, thiab haj yam ua rau neeg xiam vim ntshav qab zib.
Kuv maj nrawm los qhia txoj xov zoo - Endocrinological qhov chaw tshawb fawb ntawm Lavxias Academy ntawm Medical Science tau tswj hwm los tsim cov tshuaj uas kho cov mob ntshav qab zib mellitus kom zoo. Thaum lub sijhawm, cov hauj lwm zoo ntawm cov tshuaj no tau nce mus txog 98%.
Lwm qhov xov xwm zoo: Lub Tsev Haujlwm Saib Xyuas Kev Noj Qab Haus Huv tau txais kev nyab xeeb qhov kev saws me nyuam ntawm cov haujlwm tshwj xeeb uas them rau cov nqi tshuaj ntau. Hauv Lavxias, neeg mob ntshav qab zib kom txog thaum lub Tsib Hlis 18 (suav nrog) tuaj yeem tau txais nws - Tsuas yog 147 rubles!
Muaj ntau hom tshiab ntawm cov insulins - Humalog, NovoRapid thiab Apidra - raug xiam ntawm cov luv no. Lawv pib ua haujlwm ntxov dua, yog li lawv tswj kom tshem tawm txawm tias carbohydrates nrawm. Lawv lub sijhawm tau txo qis thiab tsis muaj lub ncov, yog li cov zaub mov muaj peev xwm ua tau ntau dua, thiab noj khoom txom ncauj tsis tas yuav xav tau. Raws li cov kev tshawb fawb, cov tshuaj ultrashort muab glycemic tswj zoo dua li Actrapid.
Kev siv cov Actrapid insulin rau ntshav qab zib tuaj yeem tsim nyog:
- hauv cov neeg mob uas ua raws li cov zaub mov muaj cov zaub mov noj kom tsawg, tshwj xeeb yog muaj ntshav qab zib hom 2,
- hauv cov menyuam yaus uas noj txhua 3 teev.
Tus nqi tshuaj ntau npaum li cas? Cov tsis muaj qhov ua tau zoo ntawm cov tshuaj insulin no yog nws cov nqi qis: 1 chav tsev ntawm Actrapid tus nqi 40 kopecks (400 rubles rau 10 ml lub raj mis), cov tshuaj hormones ultrashort - 3 zaug kim dua.
Kev tsim kho tib neeg cov kua dej muaj cov qauv tsim qauv thiab cov yam ntxwv zoo sib xws:
Analogs | Chaw tsim tshuaj paus | Nqe, tshiav. | |
daim cartridges | fwj | ||
Actrapid NM | Lub Tebchaws Denmark, Novo Nordisk | 905 | 405 |
Biosulin P | Russia, Cov Khw Muag Khoom | 1115 | 520 |
Insuman Ceev Heev GT | Belarus, Monoinsulin ntawm Czech koom pheej | — | 330 |
Humulin Tsis tu ncua | USA, Eli Lily | 1150 | 600 |
Kev hloov ntawm ib qho tshuaj insulin mus rau lwm qhov yuav tsum tau ua rau kev kho mob nkaus xwb, vim tias cov nyiaj mob ntshav qab zib yuav zam tsis dhau lub sijhawm xaiv cov ntau npaum.
Nco ntsoov kawm! Koj puas xav tias kev tswj hwm kev noj qab haus huv ntawm cov tshuaj thiab cov kua dej yog ib txoj kev los tswj cov piam thaj kom tswj? Tsis muaj tseeb! Koj tuaj yeem soj ntsuam qhov no koj tus kheej los ntawm kev pib siv nws. nyeem ntxiv >>
Pharmacodynamics thiab pharmacokinetics
Actulin cov kua dej ua los ntawm cov kab mob DNA biotechnology siv cov tshuaj tsis haum Saccharomyces cerevisiaeCov. Nws INN yog - Neeg insulin.
Cov tshuaj cuam tshuam nrog lub receptor ntawm sab nraud cytoplasmic membrane ntawm cov hlwb. Nws daim ntawv insulin receptor txojCov. Nws ua kom muaj txheej txheem nyob rau hauv dej los ntawm kev nthuav tawm biosynthesis. HLOOV lossis los ntawm kev nkag mus rau cov leeg nqaij.
Cov nqog ntawm cov piam thaj yog vim qhov nce ntawm kev thauj mus los thiab kev nqus ntawm cov nqaij mos, ua kom muaj zog lipogenesisprotein synthesis thiab glycogenogenesis, nrog rau qhov kev txo qis npaum li cas ntawm cov piam thaj los ntawm lub siab, thiab lwm yam.
Kev ua ntawm cov tshuaj pib tsis pub dhau 30 feeb tom qab thov. Cov txiaj ntsig siab tshaj plaws yog pom nyob rau nruab nrab hauv 2.5 teev. Tag nrho lub sijhawm ntawm kev ua yog 7-8 teev.
Cov yam ntxwv ntawm tus kheej rau cov neeg mob yog ua tau, suav nrog cov nyob ntawm qhov ntau thiab tsawg ntawm cov tshuaj.
Cov lus qhia rau kev siv Actrapid (Txujci thiab ntau npaum li cas)
Cov lus qhia rau Actrapid qhia tias cov tshuaj yog muab tshuaj subcutaneously lossis txhaj tshuaj. Cov koob tshuaj yog xaiv los ntawm tus kws tshaj lij ib tus zuj zus, nyob ntawm qhov xav tau ntawm tus neeg mob. tshuaj insulinCov. Raws li txoj cai, qhov tshuaj tsuas yog 0.3-1 IU / kg ib hnub. Ntawm insulin kujqhov kev thov yuav muaj ntau dua, thiab nyob rau hauv thev naus laus zis endogenous insulin ntau lawm - Hauv qab. Cov neeg mob yuav tsum ua tib zoo saib xyuas lawv cov piam thaj ntshav.
Thaum tsis hnov mob lub raum lossis lub siab ua haujlwm tshuaj insulintsawg dua. Yog li koj yuav tau kho cov tshuaj ntau npaum.
Cov lus qhia rau kev siv Actrapid qhia tias nws tuaj yeem siv nrog kev sib xyaw ntev ua yeeb yam insulins.
Cov tshuaj yog muab rau hauv ib nrab ib teev ua ntej noj mov lossis ua khoom txom ncauj nrog carbohydrates. Raws li txoj cai, cov kev txhaj tshuaj tau ua rau subcutaneously hauv thaj tsam ntawm thaj tsam ntawm sab xub ntiag phab ntsa. Qhov no muab kev nrawm nrawm. Ib qho ntxiv, kev txhaj tshuaj tuaj yeem ua rau hauv tus ncej puab, deltoid leeg ntawm lub xub pwg lossis pob tw. Yuav tiv thaiv lipodystrophyqhov chaw txhaj tshuaj yuav tsum tau hloov.
Tso cai tswjfwm yog tso cai tau yog tias kev txhaj tshuaj yog tsim los ntawm tus kws khomob. Intramuscularly, cov tshuaj yog muab rau noj tsuas yog qhia los ntawm kws tshwj xeeb.
Noj ntau dhau
Nyob rau hauv cov ntaub ntawv ntawm overdose, cov hauv qab no yog ua tau: insomniantev li ntawm pallor, ntau zog arousal thiab qab los, tshee hnyo, hws, mob taub hau, paresthesia nyob rau hauv lub qhov ncauj, palpitations. Kev siv rau hauv cov tshuaj hauv cov tshuaj ntau dua qhov tus qauv, tus neeg mob yuav poob rau rau leej twg.
Thaum lub teeb ntshav qogkoj yuav tsum noj zaub mov zoo lossis muaj suab thaj. Hauv kev noj tshuaj ntau dhau, 1 mg yog muab tshuaj intramuscularly GlucagonCov. Yog tias tsim nyog, cov ntsiab lus ntawm cov piam thaj ntxiv yuav ntxiv.
Kev sib txuam
Hypoglycemic cov nyhuv tshuaj insulinnce thaum noj qhov ncauj hypoglycemic cov neeg sawv cev, angiotensin hloov ua lwm yam enzyme inhibitors, tsis xaiv-beta-blockers, sulfonamides, tetracycline, Ketoconazole, Pyridoxine, cyclophosphamidelithium npaj monoamine oxidase inhibitors thiab carbonic anhydrase, Bromocriptine, anabolic tshuaj yuam, Clofibrate, Mebendazole, Theophylline, Fenfluramine thiab cov tshuaj muaj ethanol. Cawv tsis tsuas yog txhim kho, tab sis kuj tseem lengthens cov nyhuv ntawm Actrapid.
Kev ua rau lub siab hypoglycemic, ntawm qhov tsis tooj, txo qis dua nyob rau hauv tus ntawm tshuaj tiv thaiv qhov ncauj, cov thyroid hormones, Heparina, sympathomimetics, Clonidine, Diazoxide, Phenytoin, glucocorticosteroids, thiazide diuretics, tricyclic cov tshuaj tiv thaiv kev ntxhov siabhauv, Danazole, calcium channel blockers, morphine, nicotine.
Cov nyhuv ntawm Actrapid tuaj yeem yog nce lossis tsawg dua vim yog siv cov tshuaj Reserpine thiab dej qab ntsev. Octreotide, Lanreotide tuaj yeem txo lossis nce ntxiv qhov xav tau tshuaj insulin.
Txais tos beta blockers tuaj yeem zais cov tsos mob ntshav qog thiab tiv thaiv nws tshem tawm.
Qee cov khoom lag luam, piv txwv li, muaj thiolslossis sulfitestej zaum yuav ua rau degradation tshuaj insulin.
Hnub tas sij hawm
Lub raj mis qhib qhib tau khaws cia tsis pub dhau 6 lub lis piam. Ua ntej qhib, lub txee lub neej ntawm cov tshuaj yog 30 lub hlis. Tsis txhob siv cov tshuaj tom qab hnub tas sij hawm.
Kev tshuaj xyuas cov xeeb ceem Actrapid yog ib qho tshuaj uas ntseeg siab tau uas tso cai rau koj kom tau txais kev kwv yees txhauvCov. Cov neeg mob nyiam qhov ceev ntawm cov tshuaj. Ntawm qhov tsis zoo, tsuas yog ib qho tsis xis nyob hauv kev tso tawm ntawm cov tshuaj hauv daim ntawv ntawm kev daws rau kev txhaj tshuaj, cov kev qhia ntawm uas feem ntau xav tau kev saib xyuas tshwj xeeb.
Tus nqi twv, qhov twg yuav
Nqi Actrapida txog 450 rubles. Koj tuaj yeem yuav cov cuab yeej no nkaus xwb los ntawm cov tshuaj noj.
Nqi Insulin Actrapid HM Penfill yog kwv yees li 950 rubles. Yog li, cov tshuaj yog suav tias kim heev. Hauv qee lub tsev muag tshuaj online, tus nqi ntawm Actrapid yuav siab dua li qhia.
Kev Sib Sau thiab daim ntawv ntawm kev tso tawm
Kev daws rau kev txhaj tshuaj - 1 ml:
- cov tshuaj nquag: insulin soluble tib neeg kev tsim kho engineering - 100 IU (3.5 mg), 1 IU sib raug rau 0.035 mg ntawm cov tshuaj insulin tsis txaus,
- kev tshem tawm: zinc chloride, glycerin (glycerol), metacresol, sodium hydroxide thiab / lossis hydrochloric acid (los kho pH), dej rau kev txhaj tshuaj.
10 ml hauv lub khob fwj, ntim nrog tus tuav roj hmab thiab lub hau yas, hauv ib pob duab los qhia 1 lub raj mis.
Kev daws rau kev txhaj tshuaj yog pob tshab, tsis muaj kob.
Cov neeg ua yeeb yam luv luv.
Tib neeg siv tshuaj insulin DNA insulin. Nws yog cov insulin ntawm lub sijhawm ua haujlwm ntev. Regulates ntshav qabzib metabolism, muaj cov teebmeem anabolic. Hauv cov leeg nqaij thiab lwm cov nqaij (tshwj tsis yog lub hlwb), cov roj ntsha insulin thauj cov ntshav qabzib thiab amino acids ntau dua, thiab txhim kho cov protein anabolism. Insulin txhawb kev hloov pauv ntawm cov piam thaj rau glycogen hauv lub siab, inhibits gluconeogenesis thiab txhawb kev hloov pauv ntawm cov piam thaj rau cov rog.
Actrapid nm Siv rau hauv kev xeeb tub thiab menyuam yaus
Thaum cev xeeb tub, nws yog qhov tseem ceeb tshwj xeeb kom tswj tau glycemic zoo hauv cov neeg mob ntshav qab zib. Thaum cev xeeb tub, qhov xav tau rau cov tshuaj insulin feem ntau poob qis hauv thawj peb lub hlis thiab nce hauv qib thib ob thiab thib peb.
Nws raug nquahu kom cov neeg mob ntshav qab zib mellitus qhia tus kws khomob txog qhov pib lossis npaj lossis cev xeeb tub.
Hauv cov neeg mob uas mob ntshav qab zib mellitus thaum lactation (pub niam mis), yuav tsum tau txhaj tshuaj kho cov tshuaj insulin, zaub mov noj, lossis ob qho tib si ob leeg tuaj yeem xav tau.
Hauv kev tshawb fawb ntawm kev tshuaj lom neeg caj ces hauv cov tshuaj lom hauv vitro thiab hauv vivo, tib neeg cov tshuaj insulin tsis muaj qhov tshwm sim mutagenic.
Actrapid nm Sab sij huam
Los ntawm cov kab ke endocrine: hypoglycemia.
Kev mob ntshav qis heev tuaj yeem ua rau tsis nco qab thiab (tshwj tsis yog kis) tuag.
Ua xua: muaj kev fab rau lub zos yog ua tau - hyperemia, o lossis khaus ntawm qhov chaw txhaj tshuaj (feem ntau tso tseg li ntawm ob peb hnub mus rau ntau lub lis piam), kev tiv thaiv kab mob tsis haum (tshwm sim tsawg dua, tab sis muaj dua) - ua pob khaus, ua tsis taus pa, ua pa luv , txo cov ntshav siab, ntshav nce siab, nce hws. Cov uas muaj mob hnyav raug neeg lub cev tuaj yeem tas sim neej.
Hypoglycemic nyhuv txo qis los ntawm kev tiv thaiv kab mob hauv qhov ncauj, corticosteroids, thyroid hormone npaj, thiazide diuretics, diazoxide, tricyclic antidepressants.
Cov nyhuv hypoglycemic yog txhim kho los ntawm qhov ncauj hypoglycemic tshuaj, salicylates (e.g. acetylsalicylic acid), sulfonamides, MAO inhibitors, beta-blockers, ethanol thiab ethanol-muaj cov tshuaj.
Beta-blockers, clonidine, reserpine tuaj yeem npog qhov tsos ntawm cov tsos mob ntawm qog ntshav qab zib.
Tsuas tshuaj Actrapid nm
P / c, hauv / hauv. Cov koob tshuaj ntawm cov tshuaj tau xaiv ib qho zuj zus rau hauv qhov kev xav tau ntawm tus neeg mob. Feem ntau, cov neeg mob xav tau cov tshuaj insulin yog li 0.3 mus rau 1 IU / kg / hnub. Kev xav tau txhua hnub rau insulin tuaj yeem siab dua nyob rau hauv cov neeg mob uas muaj insulin tsis kam (piv txwv li, thaum pub, nrog rau cov neeg mob rog rog) thiab qis dua hauv cov neeg mob uas muaj cov insulin endogenous ntau lawm.Yog tias cov neeg mob ntshav qab zib ua tiav kev tswj glycemic zoo, ces cov teeb meem ntshav qab zib feem ntau tshwm sim tom qab. Hauv kev hais txog qhov no, ib qho yuav tsum sib zog ua kom ua tau zoo ntawm kev tswj cov metabolism hauv, tshwj xeeb, los ntawm kev ua tib zoo saib xyuas seb cov piam thaj hauv cov ntshav yuav zoo li cas.
Actrapid ® NM yog cov tshuaj insulin luv luv thiab tuaj yeem siv nrog cov insulins ntev ntev.
Cov tshuaj tau muab noj 30 feeb ua ntej noj mov lossis noj khoom txom ncauj uas muaj cov carbohydrates. Actrapid ® NM feem ntau yog muab sc rau thaj tsam ntawm thaj chaw ntawm sab xub ntiag ntsa. Yog tias qhov no yooj yim, tom qab ntawd los kuj tuaj yeem ua rau tus ncej puab, thaj av gluteal lossis thaj tsam ntawm deltoid leeg ntawm lub xub pwg. Nrog kev qhia txog cov tshuaj mus rau thaj av ntawm thaj chaw ntawm sab xub ntiag phab ntsa, kev nqus sai tau tiav ntau dua nrog kev qhia rau lwm thaj chaw. Ua kev txhaj tshuaj rau hauv cov tawv nqaij txo qhov kev pheej hmoo ntawm kev nkag mus rau hauv cov leeg nqaij.
Nws yog ib qho tsim nyog yuav tsum hloov chaw txhaj tshuaj nyob rau thaj tsam anatomical thiaj li tiv thaiv kev txhim kho ntawm lipodystrophy.
Intramuscular txhaj tshuaj kuj tuaj yeem ua tau, tab sis tsuas yog qhia los ntawm kws kho mob.
Actrapid-NM kuj tseem tuaj yeem nkag mus rau hauv / thiab, thiab cov txheej txheem zoo li no tsuas yog ua tau los ntawm tus kws kho mob.
Nrog kev puas tsuaj rau lub raum lossis mob siab, xav tau cov insulin tsawg dua.
Hloov chaw ntawm tus neeg mob mus rau lwm hom insulin lossis kev npaj tshuaj insulin nrog cov npe lag luam txawv yuav tsum tshwm sim nyob rau hauv kev saib xyuas mob nkeeg nruj.
Kev hloov pauv ntawm cov kev ua ub no ntawm insulin, nws hom, hom (nqaij npuas, tib neeg insulin, tib neeg insulin, los yog cov qauv tsim tawm (DNA recombinant insulin lossis insulin ntawm keeb kwm tsiaj)) yuav tsum tau hloov kho koob tshuaj.
Qhov xav tau koob tshuaj yuav tau siv nyob rau ntawm thawj coj thawj coj ntawm tib neeg cov tshuaj insulin tom qab npaj cov tshuaj insulin ntawm cov tsiaj keeb kwm los yog maj mam dhau ob peb lub lis piam lossis ntau lub hlis tom qab hloov.
Txoj kev xav tau cov tshuaj insulin tuaj yeem txo nrog adrenal tsis txaus ua haujlwm, pituitary lossis thyroid caj pas, nrog lub raum lossis lub siab ua haujlwm.
Nrog rau qee qhov mob lossis kev ntxhov siab hauv lub siab, qhov xav tau rau insulin yuav nce.
Koob tshuaj yuav tau siv thaum nce ua si lossis thaum pauv noj zaub mov zoo.
Cov tsos mob ua ntej ntawm hypoglycemia thaum tswj hwm ntawm tib neeg cov tshuaj insulin hauv qee cov neeg mob tej zaum yuav tsawg dua los yog txawv ntawm cov uas tau pom thaum tswj hwm tsiaj insulin. Nrog kev ua haujlwm ntawm cov ntshav qabzib hauv lub cev, piv txwv li, los ntawm kev kho mob insulin ntau ntxiv, txhua yam lossis qee qhov tsos mob ntawm cov tsos mob ntawm lub qog ntshav yuav ploj, hais txog qhov twg cov neeg mob yuav tsum tau ceeb toom.
Cov tsos mob ua ntej ntawm lub qog ntshav qab zib tuaj yeem hloov lossis tsis tau hais tawm nrog lub sijhawm ntev ntawm mob ntshav qab zib mellitus, mob ntshav qab zib neuropathy, lossis siv cov beta-blockers.
Muaj qee kis, kev tsis haum tshuaj nyob hauv zos tuaj yeem yog los ntawm cov laj thawj tsis cuam tshuam nrog kev txiav txim ntawm cov tshuaj, piv txwv li, voos tawv nqaij nrog cov tshuaj ntxuav kom huv lossis siv tshuaj tsis raug.
Muaj qee zaus, txaws kev tsis haum tshuaj, yuav tsum kho tamsid. Qee zaum, yuav tsum tau hloov cov insulin lossis desensitization.
Cuam tshuam rau kev muaj peev xwm tsav tsheb thiab tswj cov tshuab
Thaum lub sij hawm hypoglycemia, tus neeg mob lub peev xwm los mloog zoo yuav txo qis thiab tus lej ntawm psychomotor cov tshuaj tiv thaiv yuav tsawg. Qhov no tuaj yeem txaus ntshai nyob rau hauv qhov xwm txheej uas qhov peev xwm no tshwj xeeb tshaj yog (tsim nyog tsav tsheb los yog siv tshuab ua haujlwm). Cov neeg mob yuav tsum qhia rau lawv kom ceev faj kom tsis txhob mob ntshav qab zib thaum tsav tsheb.Qhov no tseem ceeb tshwj xeeb tshaj yog rau cov neeg mob uas cov tsos mob me lossis tsis tuaj-ua ntej-ntawm cov ntshav lub qog lossis nrog kev loj hlob ntawm hypoglycemia nquag. Hauv cov xwm txheej zoo li no, tus kws kho mob yuav tsum soj ntsuam qhov ua tau ntawm tus neeg mob tsav tsheb.
Cov chaw muag tshuaj
Actrapid yog cov tshuaj insulin luv luv, uas muag muag ua tshuaj tov. Cov tshuaj muaj cov nyhuv hypoglycemic, pab txo cov ntshav qab zib. Qhov no yog vim muaj kev thauj mus los ntawm cov piam thaj mus rau lub hlwb ntawm cov nqaij thiab cov plab hnyuv siab raum, nws txoj kev nqus sai thiab ua tiav. Cov tshuaj insulin stimulates glycogenesis thiab lipogenesis, ua kom muaj protein ntau thiab txo cov nqi ntawm cov suab thaj ua ke los ntawm daim siab.
Cov tshuaj muaj cov tib neeg insulin, uas tau txais los ntawm kev hloov caj ces. Tsis tas li ntawd, cov muaj pes tsawg leeg suav nrog glycerin, cov tshuaj uas ua kom cov kua qaub-puag tus lej, thiab zinc chloride. Cov tshuaj raug muag nyob hauv tshwj xeeb 3 ml cartridges tsim los rau cov koob txhaj tshuaj.
Lub sijhawm tiv thaiv ntawm Actrapid insulin yog nyob ntawm qhov ntau npaum li cas, qhov chaw thiab txoj kev ntawm kev coj ua ntawm kev txhaj tshuaj. Yog li, nrog kev txhaj tshuaj subcutaneous, thawj cov nyhuv pom tom qab ib nrab teev, thiab qhov txiaj ntsig siab tshaj plaws tau sau tseg tom qab 2 teev. Lub sijhawm tag nrho ntawm cov tshuaj insulin hauv cov ntshav yog 8 teev.
Hauv cov khw muag tshuaj koj tuaj yeem pom cov tshuaj analogues ntawm cov tshuaj: Iletin II Tsis tu ncua, Actrapid MS, Betasint nruab nrab E-40, Maxirapid BO-S thiab lwm tus. Kev hloov tshuaj Insulin tsuas yog tso cai nkaus xwb uas tus kws kho mob tau hais tseg tom qab sab laj nrog nws.
Phiv thiab haus tshaj
Kev phiv los ntawm Actrapid insulin tuaj yeem tshwm sim nrog lub cev ua kom lub zog dhau mus, ua tsis tau raws li cov tshuaj pom zoo lossis noj tsis txaus. Cov kws kho mob ntshav qab zib txhawj xeeb txog kev o ntawm caj npab thiab txhais ceg, qis dua qhov muag pom, nce tawm hws, tshee thiab pallor ntawm daim tawv nqaij. Kev tsis zoo nyob rau hauv qhov chaw, ua kom muaj kev kub ntxhov thiab qaug zog yog qhov ua tau.
Feem ntau, cov neeg mob ntshav qab zib yws yws txog mob taub hau thiab kiv taub hau, xeev siab thiab muaj kev tshaib plab. Hauv qee kis, poob ntawm kev nco qab thiab kev loj hlob ntawm ib qho insulin tsis nco qab muaj peev xwm ua tau.
Nrog rau kev nkag siab zoo rau cov tshuaj, cov neeg mob yuav ua kev tsis haum tshuaj. Tus mob yog pom los ntawm kev ntuav, tawm hws ntau dhau, kiv taub hau, mob plawv, thiab ua pa nyuaj.
Tej zaum qhov kev txhim kho ntawm cov tshuaj tiv thaiv hauv ib cheeb tsam hauv qhov chaw txhaj tshuaj: liab liab, o thiab khaus. Nrog kev hno tsis tu ncua hauv ib thaj chaw, lipodystrophy tuaj yeem tshwm sim.
Tshaj dhau cov tshuaj noj ntau npaum ntawm Actrapid ua rau kev txhim kho hypoglycemia. Nws yog pom los ntawm kev qaug zog, tshaib plab loj, ua kom duav thiab nqaj ntawm daim tawv nqaij. Qhov xaus txaus ntshai tshaj plaws rau qhov mob no yog qhov ua rau tsis nco qab lawm.
Cov Tshuaj Tiv Thaiv:
Cev xeeb tub thiab lactation
Tsis muaj kev txwv txog kev siv cov tshuaj insulin thaum cev xeeb tub, vim tias cov tshuaj insulin tsis hla qhov chaw tiv thaiv. Ntxiv mus, yog tias cov ntshav qab zib tsis tau kho thaum cev xeeb tub, tus me nyuam hauv plab yog qhov muaj kev pheej hmoo. Yog li, kho cov ntshav qab zib yuav tsum txuas ntxiv thaum cev xeeb tub.
Ob lub qog ntshav qab zib thiab hyperglycemia, uas tuaj yeem tsim kho thaum muaj kev xaiv tsis zoo, ua rau muaj kev pheej hmoo ntawm cov mis tsis ua haujlwm thiab kev tuag ntawm tus menyuam hauv plab. Cov poj niam cev xeeb tub uas muaj ntshav qab zib yuav tsum tau saib xyuas thoob plaws lub sijhawm lawv cev xeeb tub, lawv yuav tsum muaj kev tswj xyuas cov ntshav qabzib ntau ntau, cov lus qhia zoo ib yam rau cov poj niam uas npaj xeeb menyuam.
Qhov kev xav tau rau insulin feem ntau poob qis hauv thawj peb lub hlis thaum cev xeeb tub thiab maj mam nce ntxiv hauv qib thib ob thiab thib peb.
Tom qab yug menyuam tas, xav tau cov tshuaj insulin sai sai rau qib uas tau sau tseg ua ntej muaj menyuam hauv plab.
Nws kuj tseem tsis muaj kev txwv rau kev siv tshuaj Actrapid NM thaum pub niam mis.Ua kev kho mob rau cov leej niam laus tsis muaj teeb meem rau tus menyuam. Txawm li cas los xij, tus niam yuav tsum tau kho qhov tshuaj ntau dua ntawm Actrapid NM thiab / lossis kev noj haus.
Sab sij huam:
Tsis tshua muaj heev - kev siv tshuaj anaphylactic. Cov tsos mob ntawm cov tsos mob ua kom yuag tuaj yeem suav nrog kev ua pob khaus tawv nqaij, khaus, tawm hws ntau dhau, cuam tshuam ntawm txoj hnyuv, mob caj pas, mob caj dab, ua tsis taus pa, mob taub hau, poob ntshav siab, tsaus muag / tsis nco qab.
Generalized hypersensitivity kev tsis haum yuav ua rau lub neej neeg.
Kev tsis taus ntawm lub paj hlwb
Ncaj qhawv - peripheral neuropathy.
Yog tias kev txhim kho hauv cov ntshav qabzib tau tiav sai heev, ib qho xwm txheej hu ua "mob hnyav mob hlwb" yuav tshwm sim uas feem ntau yuav hloov tau.
Ua txhaum ntawm lub cev ntawm lub zeem muag
Tau yooj yim - qhov yuam kev yooj yim.
Kev cuam tshuam ntawm kev tawm tsam feem ntau yog sau tseg thaum pib ntawm kev siv tshuaj insulin. Raws li txoj cai, cov tsos mob no yuav thim rov qab.
Tsis tshua muaj heev - mob ntshav qabzib retinopathy. Yog tias tswj tau glycemic txaus yog muab rau lub sijhawm ntev, qhov kev pheej hmoo ntawm kev nce qib ntawm cov ntshav qab zib ua kom tsawg dua. Txawm li cas los xij, qhov kev siv tshuaj insulin ntau dua nrog kev txhim kho ntse nyob hauv kev tswj glycemic tuaj yeem ua rau muaj kev nce ntxiv mus ib ntus rau ntawm qhov mob ntshav qab zib retinopathy.
Kev ua mob ntawm daim tawv nqaij thiab cov nqaij mos
Ntxim ntxub - lipodystrophy.
Lipodystrophy tuaj yeem tsim kho ntawm qhov chaw txhaj tshuaj hauv qhov xwm txheej thaum lawv tsis hloov tas mus li thaj chaw txhaj tshuaj hauv thaj tsam ntawm lub cev.
Kev mob siab ntawm lub cev tag nrho, nrog rau kev tawm tsam ntawm thaj chaw txhaj tshuaj
Yaug tawm - kev tsis haum ntawm qhov chaw txhaj tshuaj.
Tawm tsam keeb kwm yav dhau los ntawm kev siv tshuaj insulin, cov tshuaj tiv thaiv tuaj yeem tshwm sim ntawm qhov chaw txhaj tshuaj (liab ntawm daim tawv nqaij, o, khaus, mob, hematoma tsim ntawm qhov chaw txhaj tshuaj). Txawm li cas los xij, nyob rau hauv Feem ntau, cov kev hloov no tshwm sim nyob rau hauv qhov thiab ploj thaum kho.
Ntxeev dhau - puffiness.
Feem ntau o nyob rau theem pib ntawm kev siv tshuaj insulin. Raws li txoj cai, qhov tsos mob no yog rau hauv qhov.
Chaw tsim tshuaj paus:
Kev daws rau kev txhaj tshuaj Actrapid NM (cov lus qhia rau kev siv, nws kom meej meej tshuaj) yog pom zoo rau cov neeg muaj ntshav qab zib. Cov tshuaj yog raws li tib neeg cov tshuaj insulin tau txais biosynthetically. Nws lub chaw tsim khoom yog lub tuam txhab tshuaj Novo Nordisk A / S los ntawm Denmark, koom nrog kev tsim kho thiab tsim cov tshuaj rau ntshav qab zib. Actrapid tsuas yog siv raws li tus kws kho mob tau qhia thiab yog xa tawm los ntawm lub khw muag tshuaj nrog rau daim ntawv teev tshuaj.
Nquag tivthaiv thiab cuam tshuam ntawm cov tshuaj, kev qhia rau nws lub hom phiaj
Actrapid NM yog hypoglycemic tus neeg saib xyuas nrog lub ntsej muag luv luv. Nws yog tsim nyob rau hauv cov qauv ntawm cov kua pob tshab tsis muaj xim thiab tsw, npaj rau kev tswj hwm hauv qab ntawm daim tawv nqaij thiab leeg leeg. Cov nquag ua haujlwm ntawm cov tshuaj yog soluble tib neeg insulin, tau siv cov txheej txheem rDNA biotechnology siv cov tshuaj Saccharomyces cerevisiae strain. Hauv 1 ml ntawm kev daws yog 100 IU ntawm cov tshuaj nquag, uas yog sib npaug rau 0.035 anhydrous insulin. Ntxiv rau cov tshuaj yeeb dej caw, cov khoom ntxiv nrog rau cov dej tsis huv, sodium hauv daim ntawv ntawm hydroxide, zinc chloride, metacresol thiab hydrochloric acid.
Cov tshuaj raug muag muag hauv cov ntshiab ntshiab iav fwj ntawm 10 ml, kaw nrog roj hmab nres. Txhua lub raj mis tau ntim rau hauv ib lub thawv ntawv uas muaj cov ntawv tuab thiab muaj cov ntawv cim kho mob.
Cov khoom qab zib-txo cov khoom ntawm Actrapid NM yog vim qhov nqus ntawm cov kua nplaum los ntawm lub cev tom qab kev khi ntawm cov kua dej los rau cov cell receptors thiab qhov inhibition ntawm nws cov khoom los ntawm lub siab. Cov cuab yeej yog cim los ntawm kev txiav txim siab luv luv.Cov nyhuv ntawm nws siv tshwm sim nyob rau hauv ib nrab teev tom qab qhov koob tshuaj thiab kav ntev txog 8 teev. Qhov siab tshaj plaws ntawm kev ua kom nquag plias ntawm Actrapid NM hauv cov ntshav ntshav yog pom tom qab 1.5-2 teev tom qab txhaj tshuaj.
Actrapid NM yog siv rau hauv kev kho mob ntawm ntshav qab zib mob ntshav qab zib mellitus hauv cov neeg ntawm txhua lub hnub nyoog. Vim tias qhov kev txiav txim sai, cov tshuaj yuav siv tau rau hauv cov mob tseem ceeb thaum tus neeg mob tau teeb meem nrog kev tswj glycemic.
Cov xwm txheej hauv kev ceev faj uas yuav tsum tau nrog tshuaj
Cov neeg muaj kev mob ntshav qab zib yuav tsum paub tias kev siv Actrapid NM tsis yog qhia rau txhua tus neeg mob. Cov lus qhia rau kev siv txwv tsis pub teem caij rau cov tshuaj no rau cov neeg uas muaj:
- tus neeg tsis kam txais ntawm nws cov khoom tawm tsam,
- ntshav qog.
Kev siv cov Actrapid NM hauv kev xyaum kho mob tsis yog contraindicated. Cov tshuaj no tuaj yeem siv rau hauv kev kho mob rau menyuam yaus thiab tub ntxhais hluas uas xav tau kev txhaj tshuaj nrog insulin los tswj cov ntshav qab zib kom nyob zoo.
Nws tsis yog yam tshwm sim rau cov kua tshuaj insulin los mus rau hauv qhov chaw tiv thaiv qhov chaw, yog li nws tuaj yeem siv los ntawm cov neeg mob cev xeeb tub tsis muaj kev txwv. Cov poj niam uas tab tom npaj rau kev ua leej niam yuav tsum xaiv cov tshuaj kom ntau, uas yuav ua rau lawv tswj lawv cov ntshav qab zib kom qis. Kev siv cov tshuaj hauv cov tshuaj tsis txaus tuaj yeem ua rau muaj qhov tshwm sim ntawm kev mob ntshav qab zib lossis hyperglycemia - mob uas thaum lub sijhawm cev xeeb tub tuaj yeem ua rau tsis meej txoj kev loj hlob thiab tuag ntawm tus me nyuam hauv plab.
Cov neeg cia siab niam yuav tsum ua tib zoo kho qhov koob tshuaj Actrapid NM. Nws yuav tsum tau yug los hauv lub siab tias hauv thawj peb lub hlis twg, qhov xav tau nws poob qis me ntsis, thiab hauv qee lub sijhawm tom qab nws nce. Tom qab yug me nyuam tas, tus poj niam xav tau cov tshuaj insulin maj mam rov qab los txog theem uas nws muaj ua ntej pib qhov xwm txheej "ntxim nyiam".
Actrapid NM tsis muaj teeb meem rau kev noj qab haus huv ntawm cov menyuam mos, yog li ntawd, tsis tas yuav txwv nws txoj kev siv rau kev pub mis niam. Qee zaum ib tus niam hluas yuav xav tau ib qho tshuaj kho kom haum.
Hauv cov tib neeg uas mob raum thiab mob siab tsis txaus, lub cev xav tau cov tshuaj insulin tuaj yeem txo qis. Lawv yuav tsum ua tib zoo saib xyuas qib ntshav qabzib hauv cov ntshav thiab suav cov tshuaj ntawm cov tshuaj ib tus zuj zus, raws cov txiaj ntsig ntawm kev tshuaj ntsuam.
Kev siv cov Actrapid NM hauv cov neeg tshaj 65 yuav tsum tau ua tawm tsam keeb kwm ntawm kev saib xyuas cov kua nplaum tas li. Txhawm rau kom tsis txhob muaj kev txhim kho ntawm qhov tsis zoo los ntawm kev kho mob, cov neeg mob ntawm cov hnub nyoog no yuav tsum sim ua kom tsis txhob ntau tshaj qhov ntau ntawm cov tshuaj.
Cov tshuaj tsis cuam tshuam rau tib neeg kev muaj peev xwm. Cov neeg mob uas siv tsis tu ncua los tsim cov xeeb ntxwv tsis pub ua.
Cov yam ntxwv ntawm daim ntawv thov thiab qhov tsis tuaj yeem xav tau
Actrapid yuav tsum muab tshuaj rau hauv qab daim tawv nqaij los yog cev nqaij pob txha. Qhov ntau thiab tsawg ntawm cov tshuaj yog nyob ntawm tus neeg mob xav tau cov tshuaj insulin. Tus kws endocrinologist yuav tsum nruab nws raws li kev kuaj ntshav qab zib. Cov tshuaj no muaj cov nyhuv rau lub sijhawm luv luv, yog li ntawd, yog tias tsim nyog, nws tuaj yeem tsim kho nyob rau hauv kev sib xyaw nrog kev ua haujlwm ntev insulin npaj.
Kev daws tshuaj ntawm Actrapid NM raug nquahu kom siv li ib nrab teev ua ntej noj mov. Nrog rau kev siv subcutaneous, nws yog qhov xav tau los qhia cov tshuaj rau hauv phab ntsa anterior ntawm peritoneum. Koj tuaj yeem tso cov tshuaj insulin rau hauv xub pwg, ncej puab lossis gluteal. Txhawm rau zam kev txhim kho ntawm cov roj ntsha tsis sib haum, tus neeg mob yuav tsum tsis tu ncua hloov qhov chaw ntawm kev qhia ntawm kev daws. Los ntawm kev txiav txim siab ntawm tus kws kho mob, tus neeg mob yuav yog lub npe qhia ntawm Actrapid NM ua ke nrog. Cov txheej txheem no yog nqa tawm hauv lub tsev kho mob.
Kev siv cov Actrapid NM tuaj yeem ua rau kev txhim kho cov kev tsis haum ntawm tib neeg.Qhov tshwm sim feem ntau uas tsis muaj qhov xav tau ntawm kev kho nrog cov tshuaj no yog hypoglycemia, uas tshwm sim los ntawm kev siv tshuaj ntau ntawm cov tshuaj insulin thiab tau kuaj pom tias muaj ntshav qab zib tsawg. Nrog rau daim ntawv me me ntawm cov kab mob pathology no, ib tus neeg muaj kev tsis txaus siab ntawm nkees, tsis muaj zog, nqhis dej, xeev siab, qhuav ntawm daim tawv nqaij, tsis muaj qab los noj mov, tso zis heev, ua tsis taus pa.
Kev mob ntshav nce siab ntau tuaj yeem raug lees paub los ntawm tus mob huam tsis txaus, tsaus muag, lub hlwb tsis ua haujlwm. Yog tias tsis muaj txoj hauv kev txaus rau kev kho, tus kab mob no tuaj yeem ua rau tus neeg tuag. Tus mob hypoglycemia, tus neeg mob ntshav qab zib yuav tsum caiv los ntawm cov tshuaj insulin tom ntej thiab nrhiav kev pab kho mob kom sai li sai tau
Ntxiv rau qhov ua rau lub qog ntshav ntshav, tus neeg mob uas tau txais Actrapid NM txhaj tshuaj tuaj yeem yuav pom cov tsos mob ntawm lub cev tsis zoo rau qhov yeeb tshuaj, uas tau pom tias kev txo qis hauv cov ntshav siab, tawv nqaij ua pa, ua pa luv, tachycardia, tawm hws, dyspepsia, Quincke's edema, tsis meej lossis tsis nco qab. Xws li qhov tshuaj tiv thaiv cov tshuaj kho tau suav tias yog kev phom sij txog lub neej thiab xav tau kev kho mob sai sai.
Cov kev mob tshwm sim hauv qee cov neeg uas siv cov Actrapid NM kuj muaj xws li:
- peripheral neuropathy
- cov teeb meem tsis pom kev (myopia, hyperopia, astigmatism, hyperopia, myopia),
- rog tsis pom kev,
- kev ua xua (khaus, urticaria),
- cov tshuaj tiv thaiv hauv zos (mob, khaus, o, hematomas, hyperemia ntawm qhov chaw txhaj tshuaj ntawm insulin).
Cov tsos mob tsis txaus siab uas tshwm sim hauv ib tus neeg tom qab pib siv Actrapid yuav tsum yog vim li cas nws mus ntsib kws kho mob tshwj xeeb. Kev tsis quav ntsej cov kev phiv tshuaj tuaj yeem ua rau txhim kho kev tsis tuaj yeem ua rau muaj kev noj qab haus huv.
Kev pabcuam thawj zaug thaum noj tshuaj ntau dhau, sib txuas hauv tshuaj thiab khaws cia
Kev siv cov Actrapid NM ntawm kev noj tshuaj ntau dua qhov kev txwv ua rau kev txhim kho kev noj haus ntau dhau, uas tshwm sim nws tus kheej hauv daim ntawv ntawm hypoglycemia. Pab rau tus neeg mob nyob ntawm qhov mob hnyav ntawm nws tus mob. Kev tso me ntsis hauv qab zib cov ntshav qis dua li ib txwm tsis tas mus cuag kws kho mob. Koj tuaj yeem tswj koj tus mob nrog rau tus mob ntshav qab zib los ntawm kev noj qab zib me ntsis lossis lwm yam khoom noj uas muaj cov carbohydrates ntau.
Hauv cov ntshav qog ntshav hnyav, nrog tus neeg mob swoon, tus neeg mob yuav tsum tau txais kev kho mob kub ceev. Txhawm rau tshem tawm qhov txaus ntshai rau lub neej, nws raug txhaj nrog glucagon thiab dextrose. Txhawm rau kom tsis txhob rov qab ua dua nyob rau hauv cov piam thaj, tus neeg mob tau muab cov khoom noj uas yog carbohydrate tom qab nws fainted.
Actulin insulin cuam tshuam nrog qee pawg tshuaj. Rau cov uas noj beta-blockers, tetracycline tshuaj tua kab mob, sulfonamides, steroidal anabolics, carbonic anhydrase inhibitors, monoamine oxidase thiab ACE inhibitors, ketoconazole, theophylline, mebendazole, clofibrate, txo cov tshuaj qab zib rau kev siv hauv qhov ncauj, tag nrho cov tshuaj yuav tsum tau noj rau hauv;
Ua rau cov ntshav qog ntshav ntawm Actrapid NM los ntawm nws txoj kev tswj hwm ib txhij nrog glucocorticosteroids, tshuaj tiv thaiv qhov ncauj, calcium channel blockers, thiazide diuretics, sympathomimetics, morphine, heparin, danazole, tricyclic antidepressants.
Thaum muab cov tshuaj insulin nrog salicylates thiab reserpine, qhov kev xav tsis tshua pom tshwm sim yuav tshwm sim. Thaum noj cov tshuaj nrog cawv thiab ethanol-muaj cov tshuaj nyob rau hauv parallel, nws cov nyhuv ua ntau dua thiab ntev ntev.
Actrapid NM tsis sib xws nrog tshuaj noj raws li sulfites thiab thiols. Lawv ntxiv rau txoj kev daws teeb meem ua rau nws rhuav tshem.
Lub txee lub neej ntawm Actrapid NM raug txwv tsis pub dhau 30 hli txij li hnub ua khoom lag luam.Cov vials tsis siv tshuaj tau raug pom zoo kom khaws cia hauv tub yees ntawm qhov kub ntawm 2 ° C txog 8 ° C. Nws yog ib qho tseem ceeb kom ntseeg tau tias cov tshuaj insulin tsis khov, vim tias qhov no txo nws cov khoom hypoglycemic.
Tom qab qhib lub raj mis nrog cov tshuaj yuav tsum cia nyob hauv chav tsev kub hauv qhov chaw tiv thaiv los ntawm lub teeb ci ntsa iab. Cov tshuaj insulin yuav tsum tau noj rau 45 hnub. Cov tshuaj, uas tseem nyob tom qab xaus rau lub sijhawm no, yog txwv tsis pub siv.
Ua tsaug rau koj lub tswv yim.
Cov lus
Megan92 () 2 lub lis piam dhau los
Puas muaj ib tug neeg tswj kom kho tus mob ntshav qab zib kom meej? Lawv hais tias nws tsis muaj peev xwm kho tau txhua tus.
Daria () 2 lub lis piam dhau los
Kuv tseem xav tias nws tsis yooj yim sua, tab sis tom qab nyeem cov ntawv no, Kuv tau hnov qab ntev txog tus kab mob "tsis tuaj yeem" no.
Megan92 () 13 hnub dhau los
Daria () 12 hnub dhau los
Megan92, yog li kuv tau sau rau hauv kuv thawj qhov kev xav) Qhov tsis zoo nyob rau hauv rooj plaub - qhov txuas rau ib tsab xov xwm.
Sonya 10 hnub dhau los
Tab sis qhov no tsis yog sib nrauj? Vim li cas lawv muag hauv online?
Yulek26 (Tver) 10 hnub dhau los
Sonya, koj nyob lub tebchaws twg? Lawv muag nws hauv Is Taws Nem, vim tias cov khw thiab chaw muag tshuaj tau tso lawv lub cim kev ua siab phem. Ntxiv rau, kev them nyiaj tsuas yog tom qab tau txais, uas yog, thawj saib, tshawb xyuas thiab tsuas yog tom qab them nyiaj. Yog lawm, thiab tam sim no lawv muag txhua yam hauv Is Taws Nem - los ntawm cov khaub ncaws rau TV thiab rooj tog zaum.
Editorial Teb 10 hnub dhau los
Sonya, nyob zoo. Cov tshuaj no rau kev kho mob ntshav qab zib mellitus yog tiag tiag tsis muag los ntawm lub khw muag tshuaj lub network kom tsis txhob muaj cov tshuaj ntau dhau. Txog hnub, koj tuaj yeem xaj tau tsuas yog ntawm lub vev xaib raug cai. Noj qab nyob zoo!
Sonya 10 hnub dhau los
Insulin Actrapid yog siv yeeb tshuaj rau hom 1 thiab hom 2 mob ntshav qab zib mellitus, zoo li rau kev txwv tsis pub muaj tus mob hyperglycemia. Nws normalizes ntshav qab zib thiab txhawb kev nyob zoo. Txhawm rau txhim kho cov nyhuv thiab tswj kom muaj qhov zoo tshaj plaws ntawm cov piam thaj, nws raug nquahu kom muab cov tshuaj nrog cov insulin ntev ntev thiab lwm yam tshuaj tiv thaiv kab mob.
Cov lus qhia tshwj xeeb
Txhawm rau kom tau txais cov txiaj ntsig tshwm sim los ntawm kev siv cov tshuaj, nws yuav tsum ua ke nrog kev ua yeeb yam ntev lossis nruab nrab. Nyob rau lub sijhawm kho mob, soj ntsuam cov ntshav qab zib kom tsis tu ncua kom ncav sijhawm thiab tiv thaiv kev txhim kho ntshav lossis ntshav qab zib tsawg.
Txhawm rau kom tsis txhob lipodystrophy, tas li hloov chaw txhaj tshuaj.
Insulin Actrapid yog siv thaum cev xeeb tub. Hauv lub hlis thib ib, kev xav tau rau ib yam tshuaj tsawg zuj zus, thiab ib hnub tom qab tau nce siab dua, yog li cov tshuaj ntau yuav maj mam ntau zuj zus. Cov koob tshuaj yog txiav txim los ntawm tus kws kho mob hauv txhua kis ntawm tus kheej, coj mus rau hauv tus account tus yam ntxwv ntawm lub cev thiab hom kev xeeb tub.
Tom qab yug menyuam, tus poj niam yuav tsum rov qab mus rau qhov ntim ntawm insulin uas nws tau txais ua ntej xeeb tub. Txawm li cas los xij, thaum lub sijhawm lactation, qhov xav tau rau lub cev hormone yuav poob qis, yog li nws yog ib qho tseem ceeb uas yuav tsum tau saib xyuas tas li ntawm cov piam thaj thiab koj lub cev.
Thaum lub sijhawm siv cov tshuaj, muab kev ua haujlwm uas yuav tsum tau teb sai thiab muaj kev saib xyuas ntau ntxiv. Cov kev txwv no siv rau kev tsav tsheb. Qhov no yog vim qhov tseeb tias nrog hypoglycemia, tus nqi teb rau sab nraud stimuli tuaj yeem raug txo kom tsawg.
Hypo- thiab hyperglycemia thaum siv tshuaj
Kev siv cov Actrapid insulin tuaj yeem ua rau kev txhim kho hypoglycemia (txo qis hauv qab zib) lossis hyperglycemia (nce ntxiv nyob hauv qabzib). Qhov no yog vim qhov tsis ua raws li cov tshuaj pom zoo, kev noj zaub mov tsis txaus (hla zaub mov noj lossis ua haujlwm dhau), ua kom lub cev ua kom lub zog ntau ntxiv, ntxiv rau kev txhaj tshuaj lossis kev tswjfwm tsis zoo ntawm cov tshuaj.
Cov tsos mob hauv qab no yog cov yam ntxwv ntawm hyperglycemia: nqhis dej heev, tso zis heev, tsis qab los noj mov, xeev siab thiab liab ntawm daim tawv. Nrog ketoacidosis, qhov tsis hnov tsw ntawm acetone los ntawm lub qhov ncauj pom tshwm.Cov tsos mob ceeb toom qhia tias koj yuav tsum kuaj xyuas koj cov ntshav qab zib thiab, yog tias tsim nyog, rov qab siv tshuaj Actrapid.
Kev mob hypoglycemia yog yam tshwm sim los ntawm kev nce siab hauv lub siab, qhov tawv nqaij daj ntseg thiab qhov muag nqig. Txhawm rau kom tso tseg cov tsos mob thiab tiv thaiv kev txhim kho hypoglycemic coma, tus neeg mob raug nquahu kom noj qab zib me ntsis lossis cov khoom noj uas muaj cov khoom noj uas muaj carbohydrate ntau (ncuav qab zib, khaub noom), haus kua txiv qab zib lossis tshuaj yej. Yog tias tsis nco qab, 40% kev daws teeb meem thiab glucagon muab tshuaj rau leeg. Txhawm rau tiv thaiv kom rov mob ntxiv tom qab ua haujlwm tas, tus neeg mob tau hais kom noj zaub mov ntawm cov khoom noj khoom haus sai sai.
Cia rau cov neeg mob
Txav deb ntawm tshav ntuj. Zam txhob muab overheating lossis overcooling thiab tsis txhob cia cov tshuaj kom khov. Tsis kam siv cov tshuaj yog tias nws tau hloov xim lossis plaub ya ri (muaj kev poob mus) tau tshwm sim. Khaws cov tshuaj cia kom ncav cuag cov menyuam yaus.
Actrapid HM Penfill (Actrapid HM) - ib qho kev npaj ntawm tib neeg cov insulin, uas yog tsim tawm siv cov tshuaj tua hluav taws xob.
Nws muaj lub sijhawm luv luv ntawm kev txiav txim thiab pH nruab nrab. Nws yog nkag hauv subcutaneously. HM nyob rau hauv lub npe ntawm cov tshuaj nyob rau hauv Latin txhais tau tias "tib neeg kev tsim kho tshuab, monocomponent."
Hauv tsab xov xwm no, peb yuav xav txog vim li cas cov kws kho mob tau sau ntawv rau Actrapid NM, suav nrog cov lus qhia rau kev siv, analogues thiab tus nqi ntawm cov tshuaj no hauv cov khw muag tshuaj. Rov xyuas tiag tiag ntawm cov neeg uas twb tau siv Actrapid tuaj yeem nyeem hauv cov lus.
Pharmacological kev txiav txim
Tib neeg siv tshuaj insulin DNA insulin. Nws yog cov insulin ntawm lub sijhawm ua haujlwm ntev.
Regulates ntshav qabzib metabolism, muaj cov teebmeem anabolic. Hauv cov leeg nqaij thiab lwm cov nqaij (tshwj tsis yog lub hlwb), cov roj ntsha insulin thauj cov ntshav qabzib thiab amino acids ntau dua, thiab txhim kho cov protein anabolism. Insulin txhawb kev hloov pauv ntawm cov piam thaj rau glycogen hauv lub siab, inhibits gluconeogenesis thiab txhawb kev hloov pauv ntawm cov piam thaj rau cov rog.
Kev ntsuas rau siv
Thaum tsis hnov mob lub raum lossis lub siab ua haujlwm tshuaj insulintsawg dua. Yog li koj yuav tau kho cov tshuaj ntau npaum.
Cov lus qhia rau kev siv Actrapid qhia tias nws tuaj yeem siv nrog kev sib xyaw ntev ua yeeb yam insulins.
Cov tshuaj yog muab rau hauv ib nrab ib teev ua ntej noj mov lossis ua khoom txom ncauj nrog carbohydrates. Raws li txoj cai, cov kev txhaj tshuaj tau ua rau subcutaneously hauv thaj tsam ntawm thaj tsam ntawm sab xub ntiag phab ntsa. Qhov no muab kev nrawm nrawm. Ib qho ntxiv, kev txhaj tshuaj tuaj yeem ua rau hauv tus ncej puab, deltoid leeg ntawm lub xub pwg lossis pob tw. Yuav tiv thaiv lipodystrophyqhov chaw txhaj tshuaj yuav tsum tau hloov.
Tso cai tswjfwm yog tso cai tau yog tias kev txhaj tshuaj yog tsim los ntawm tus kws khomob. Intramuscularly, cov tshuaj yog muab rau noj tsuas yog qhia los ntawm kws tshwj xeeb.
Txoj kev ntawm daim ntawv thov
Kev ua yeeb yam luv luv yog kho rau cov neeg muaj ntshav qab zib - ua kom nyias. Txhua yam nws yog nyob ntawm theem ntawm cov piam thaj hauv cov ntshav. Ua ntej tus kws kho mob endocrinologist muab tshuaj kho nrog Actrapid muaj cov insulin, koj yuav tsum kawm cov lus qhia. Cov lus qhia rau kev siv cov tshuaj piav qhia txhua yam:
- kev txiav txim ntawm cov tshuaj
- txoj kev ntawm kev thov
- contraindications
- phiv
- muaj pes tsawg leeg.
Txoj kev ntawm daim ntawv thov ntawm actrapid nyob ntawm daim ntawv ntawm kev tso tawm. Cov tshuaj insulin luv luv yog txhaj. Nws tuaj yeem raug tswj nyob hauv qab daim tawv nqaij mus rau hauv lub pob tw, caj npab thiab lub plab. Muaj kev zam tau yog thaum siv tshuaj yaj yeeb yuav tsum raug tshuaj intramuscularly lossis intravenously. Cov tshuaj, uas tau muab tshuaj subcutaneously, muaj daim ntawv ntawm lub voos txwv.
- cov tshuaj tau muab tshuaj 30 feeb ua ntej noj mov,
- pheej nyob rau tib qho chaw, tsis txhob txhaj tshuaj insulin,
- kev nkag mus rau hauv cov hlab ntshav yuav tsum raug zam,
- tom qab tswj hwm cov tshuaj insulin, nws tsis raug nquahu kom kov thiab thawb qhov chaw txhaj tshuaj,
- yog tias koj muab cov tshuaj insulin luv luv, koj yuav tsum muab txhaj sai,
- koob tshuaj yog xam nyob ntawm seb leej twg mob, laus lossis me nyuam,
- muab koob tshuaj yog muab nyob ntawm qhov sib xyaw ntawm cov tshuaj,
- Thaum tsis nco qab lossis acidosis, cov tshuaj tau muab tshuaj pleev ib ce,
- kev txhaj tshuaj yog nqa tawm los ntawm kev saib xyuas ntawm kws kho mob.
Muaj cov neeg mob ntshav qab zib, uas nyuaj los ntawm cov kab mob sib kis. Hauv qhov no, nws yog ib qho tseem ceeb uas yuav tsum xav txog lawv cov mob. Thaum noj Actrapid raws li tshuaj insulin, nws raug nquahu kom nyeem cov lus qhia rau kev siv. Kuj tau txais lus qhia los ntawm koj tus kws kho mob. Cov kev ua ywj pheej ntawm kev siv cov tshuaj yuav ua rau muaj qhov tsis zoo.
Cov lus qhia, ua raws nrog uas yuav tsum tau saib xyuas, yuav cawm koj ntawm ntau yam teeb meem. Tab sis muaj cov xwm txheej zoo li no uas ib tug neeg tau tshwm sim. Yog li, nws raug nquahu kom xyuam xim rau cov tsos mob tsis tseeb:
- mob taub hau
- nkees
- tas li xav tau kom pw
- arrhythmia,
- hnyav tawm hws, txawm nyob hauv lub caij txias,
- tsis meej pem,
- daim tawv nqaij ua daj ntseg
- ntuav
- poj koob yawm txwv mob.
Nws yuav tsum tau yug hauv siab tias ib tus neeg uas saib xyuas tus mob kom ntev, noj qee yam tshuaj, yuav tsis pom tias muaj tsos mob ntau dhau. Cov tsos mob sib txawv nrog rau cov tshuaj tsis sib haum. Kev kho mob ntawm tus neeg mob tus mob yog tias siv ntau tshaj ib zaug tuaj yeem siv tau:
- cov lus qhia ntawm cov tshuaj tshwj xeeb nyob rau hauv daim tawv nqaij,
- qhia txog cov piam thaj hauv ntshav.
Cov hau kev zoo li no tuaj yeem tswj tus neeg mob ntshav qab zib mellitus thiab tiv thaiv nws kom tsis txhob xeev tsis xeev.
Kev Sau thiab tso cov foos
Cov khoom xyaw ua si hauv muaj pes tsawg leeg yog tib neeg cov kua dej hauv cov xim yaj. Cov neeg zam hauv cov muaj pes tsawg leeg: zinc chloride, glycerol, dej txhaj tshuaj, metacresol, sodium hydroxide.
Cov tshuaj raug muag nyob rau hauv daim ntawv txhaj tshuaj, tseem muaj ib qho actrapid nm penfill daim ntawv, uas kuj tau muag nyob rau hauv daim ntawv ntawm kev daws rau kev txhaj tshuaj subcutaneous.
Tus txheej txheem ntawm kev ua ntawm Actrapid NM
Cov khoom muaj cov tib neeg insulin tau los ntawm kev tsim hluav taws xob. Rau nws cov ntau lawm, DNA los ntawm saccharomycetes poov xab siv.
Cov tshuaj insulin khi rau cov receptors nyob rau hauv lub hlwb thiab qhov kev nyuaj no qhia qhov ntws ntawm cov piam thaj ntawm cov ntshav mus rau hauv lub cell.
Tsis tas li ntawd, Actrapid insulin nthuav tawm cov yeeb yam zoo li ntawm cov txheej txheem hauv metabolic:
- Txhim kho kev tsim glycogen hauv daim siab thiab cov leeg nqaij
- Pab txhawb kev siv cov piam thaj los ntawm cov leeg nqaij thiab cov nplais adipose rau lub zog
- Qhov rhuav tshem ntawm glycogen yog txo, zoo li yog kev tsim cov kua nplaum nyob rau hauv lub qog.
- Txhim kho cov roj ntsha tsim thiab txo cov rog rog
- Hauv cov ntshav, cov synthesis ntawm lipoproteins ntau ntxiv
- Kev siv tshuaj insulin nce ntawm tes kev loj hlob thiab faib
- Ua nrawm rau synthesis protein thiab txo qis nws cov khoom seem.
Lub sijhawm ua li cas ntawm Actrapid NM nyob ntawm lub koob tshuaj, thaj chaw txhaj tshuaj thiab hom mob ntshav qab zib. Cov yeeb tshuaj qhia nws cov khoom ib nrab ib teev tom qab kev tswj hwm, nws qhov siab tshaj plaws tau sau tseg tom qab 1.5 - 3.5 teev. Tom qab 7 - 8 teev, cov tshuaj nres nws qhov kev txiav txim thiab rhuav tshem los ntawm cov enzymes.
Qhov tseem ceeb qhia rau kev siv Actrapid insulin yog kom txo cov piam thaj hauv ntshav qab zib mellitus ob qho tib si rau kev siv tas li thiab rau kev txhim kho ntawm cov xwm txheej ceev.
Actrapid thaum cev xeeb tub
Cov tshuaj Insulin Actrapid NM tuaj yeem raug txo kom txo qis hyperglycemia hauv cov poj niam cev xeeb tub, vim nws tsis hla qhov teeb meem placental. Tsis muaj nyiaj them rau ntshav qab zib nyob rau hauv cov poj niam cev xeeb tub tuaj yeem yog qhov txaus ntshai rau tus menyuam.
Kev xaiv cov koob tshuaj rau cov poj niam cev xeeb tub yog qhov tseem ceeb heev, txij li ob qho theem siab thiab qis qab zib cuam tshuam kev cuam tshuam ntawm cov khoom hauv nruab nrog thiab ua rau muaj kev tsis zoo, nrog rau kev ua kom muaj kev pheej hmoo ntawm me nyuam hauv plab tuag.
Pib txij theem pib ntawm kev npaj cev xeeb tub, cov neeg mob ntshav qab zib yuav tsum tau saib xyuas los ntawm tus kws kho mob endocrinologist, thiab lawv tau pom tias nce qib ntawm cov ntshav qabzib.Qhov kev xav tau rau insulin tuaj yeem txo qis hauv thawj peb lub hlis thaum cev xeeb tub thiab nce hauv zaum ob thiab peb.
Tom qab yug menyuam, theem ntawm glycemia feem ntau rov qab mus rau cov nuj nqis yav dhau los uas yog ua ntej cev xeeb tub.
Rau cov niam tsev laus, lub luag haujlwm ntawm Actrapid NM kuj tsis muaj kev pheej hmoo.
Tab sis muab qhov xav tau nce rau lub cev, cov zaub mov noj yuav tsum hloov pauv, thiab yog li cov koob tshuaj insulin.
Yuav tso npe thov Actrapid NM li cas?
Cov tshuaj insulin muab cov tshuaj subcutaneously thiab txhaj tshuaj. Tsuas tshuaj yog xaiv nruj me ntsis tus kheej. Feem ntau, cov tshuaj insulin yog nyob nruab nrab ntawm 0.3 thiab 1 IU ib hnub rau ib phaus ntawm tus neeg mob lub cev. Nrog cov tshuaj insulin tsis ua hauj lwm hauv cov hluas los yog nrog rog, nws yog qhov siab dua, thiab rau cov neeg mob uas muaj kev tso pa tawm ntawm lawv tus kheej insulin, nws qis dua.
Hauv txoj kev them nyiaj mob ntshav qab zib, cov kab mob ntawm tus kab mob no tsis tshua pom muaj yav tom ntej thiab tom qab. Yog li, yuav tsum tau soj ntsuam cov ntshav qabzib tas mus li thiab xaiv cov koob tshuaj insulin uas tuav ib qib sib luag ntawm qhov ntsuas no yog qhov tsim nyog.
Actrapid NM yog cov tshuaj insulin luv luv, yog li ntawd nws feem ntau ua ke nrog cov tshuaj ncua ntev. Nws yuav tsum tau noj tshuaj rau ib nrab teev ua ntej noj mov, lossis ib qho khoom noj me me uas muaj cov carbohydrates.
Txoj kev nkag nrawm tshaj yog kev txhaj tshuaj rau hauv lub plab. Ua qhov no, nco ntsoov txhaj cov tshuaj insulin rau hauv daim tawv nqaij quav. Thaj chaw ntawm lub duav, pob tw, lossis xub pwg kuj tseem siv. Qhov chaw txhaj tshuaj yuav tsum tau hloov tas li kom tsis txhob tuaj yeem ua kev puas tsuaj rau cov ntaub so ntswg subcutaneous.
Nrog rau kev txhim kho cov ntshav qab zib nephropathy, qhov xav tau rau cov tshuaj insulin poob qis, yog li cov koob tshuaj tau hloov mus rau hauv tus account glomerular pom kev npaum li cas thiab theem ntawm lub raum tsis ua haujlwm. Hauv cov kab mob ntawm cov qog adrenal, cov thyroid caj pas, pituitary caj pas, nrog rau daim siab puas tsuaj, koob tshuaj yuav tsum tau hloov pauv.
Qhov kev xav tau rau insulin kuj hloov pauv nrog kev ntxhov siab kev xav, hloov hauv lub cev ua si lossis hloov mus rau kev noj zaub mov txawv. Txhua yam kab mob yog qhov laj thawj rau kev kho cov tshuaj insulin pom zoo nrog koj tus kws kho mob.
Yog tias cov koob tshuaj insulin tsawg, lossis tus neeg mob nws tus kheej tau tso tseg insulin, hyperglycemia yuav pib nrog cov tsos mob hauv qab no:
- Ua rau tsaug zog ntau dua qub thiab nkees.
- Nce nqhis dej.
- Xeev siab thiab ntuav ntuav.
- Daim tawv liab thiab qhuav.
- Nce tso zis.
- Tsis qab los noj mov.
- Lub qhov ncauj qhuav.
Cov tsos mob ntawm hyperglycemia tsim maj mam - ntau ob peb teev lossis hnub ntawd. Yog tias koj tsis kho koj cov piam thaj hauv ntshav, nws tshwm sim. Nws cov yam ntxwv ntawm tus kheej yog qhov tsis hnov tsw ntawm acetone hauv pa pa tawm. Txoj kev pheej hmoo ntawm hyperglycemia nce nrog cov kis kab mob thiab ua npaws.
Cov kev hloov pauv los ntawm ib hom tshuaj insulin mus rau lwm qhov yuav tsum tau xaiv cov koob tshuaj tshiab. Txhawm rau ua qhov no, koj yuav tsum sab laj nrog tus kws kho mob endocrinologist. Kev siv tshuaj Insulin Actrapid tuaj yeem siv tsis tau rau hauv cov tshuaj insulin twj, thaum tsis muaj lub hau tiv thaiv ntawm lub vial, yog tias nws tau khaws cia tsis raug lossis raug khov, thiab tseem yog tias cov tshuaj ua huab.
Txog kev txhaj tshuaj, koj yuav tsum ua raws li cov cai no:
- Sau cov cua mus rau hauv cov phwj hauv, uas yog sib npaug nrog cov koob tshuaj muab.
- Tso cov koob txhaj los ntawm lub ntsaws thiab nias lub piston.
- Tig lub raj mis sab hauv.
- Siv ib koob tshuaj insulin rau hauv cov phwj.
- Tshem cua thiab xyuas koob tshuaj.
Tom qab ntawd, koj yuav tsum tau txhaj tshuaj sai: muab daim tawv rau hauv qhov quav thiab ntxig cov koob txhaj tshuaj nrog rab koob rau hauv nws qhov chaw, ntawm kaum ntawm 45 degrees. Cov tshuaj insulin yuav tsum nyob hauv qab daim tawv nqaij.
Tom qab txhaj koob, rab koob yuav tsum nyob hauv qab ntawm daim tawv nqaij tsawg kawg 6 feeb kom puv nkaus tshuaj.
Phiv los ntawm Actrapid
Feem ntau cov kev mob tshwm sim thaum kev txhaj tshuaj insulin tshaj yog qhov ua kom tsis txhob mob ntshav qab zib. Nws feem ntau tshwm sim dheev thiab raug nrog pallor ntawm daim tawv nqaij, tawm hws txias, nkees heev lossis qaug zog, lub cev tsis muaj kev taw qhia, ntxhov siab, poob siab thiab tshee tshee.
Lub siab ntawm cov xim poob qis, tsaug zog tsim, qhov kev xav ntawm kev tshaib kev nqhis, qhov muag pom kev tsis zoo.Mob taub hau thiab kiv taub hau, xeev siab thiab ntuav zuj zus. Cov foos hnyav ntawm cov piam thaj hauv qab zib tuaj yeem cuam tshuam rau lub hlwb kev ua haujlwm nrog poob ntawm kev nco qab lossis tuag taus.
Yog tias ntshav qab zib kav ntev mus ntev, nrog rau tus mob ntshav qab zib neuropathy, hauv kev kho mob beta-blockers lossis lwm yam tshuaj uas ua rau cov hlab ntsha tsis sib haum, ces cov tsos mob thaum ntxov ntawm hypoglycemia tuaj yeem yog atypical, yog li koj yuav tsum tsom mus rau qib ntshav qabzib ntau.
Txhawm rau me me, koj yuav tsum noj cov piam thaj lossis kua txiv, ncuav qab zib, cov ntsiav tshuaj qabzib. Thaum muaj mob hnyav, muaj 40% cov kua nplaum tov ua ke rau kev tso ntshav, thiab glucagon muab tshuaj intramuscularly lossis subcutaneously. Tom qab tus neeg mob rov qab nco qab, nws yuav tsum noj zaub mov nrog cov khoom noj uas yooj yim.
Kev tawm tsam ntawm glycemia tuaj yeem rov ua dua nyob rau hauv ib hnub, yog li ntawd, txawm tias ib txwm muaj cov piam thaj hauv qib siab, nws yog qhov yuav tsum tau tswj hwm nws cov ntsiab lus nruj. Cov neeg mob zoo li no yuav tsum tau rov haus cov zaub mov carbohydrates.
Cov kev mob tshwm sim tsis tshua muaj tshwm sim thiab tuaj yeem tshwm sim hauv daim ntawv ntawm:
- Ua xua pob khaus los yog ua xua. Tsis tshua muaj nrog rau ib tus neeg lub cev tsis kam tus kheej - kev phiv tshuaj anaphylactic.
- Tawm hws, xeev siab thiab mob taub hau.
- Txhawb lub plawv dhia.
- Mob paj hlwb peripheral.
- Tsis hnov qab txhim kho lossis txhim kho retinopathy.
- Lipodystrophy ntawm thaj chaw txhaj tshuaj, khaus, hematoma.
- Puffiness, tshwj xeeb tshaj yog nyob rau thawj hnub ntawm kev siv.
Daim ntawv tso tawm thiab chaw ntim tshuaj insulin Actrapid NM
Cov tshuaj hauv khw muag khoom tuaj yeem yog hom: Actrapid NM Penfill insulin (nws xav tau cwj mem tshwj xeeb rau insulin), ntxiv rau insulin hauv vials (ib qho koob txhaj insulin yog xav tau rau kev txhaj tshuaj).
Ob hom kev npaj muaj ib qho kev daws teeb meem nrog lub zog ntawm 100 IU hauv 1 ml. Cov hauv qab ntim muaj 10 ml, thiab daim cartridges - 3 ml ntawm 5 daim ib pob. Cov lus qhia rau kev siv yog txuas rau txhua daim ntawv tso tawm.
Tus nqi ntawm Actrapid hauv hwj yog qis dua tus nqi ntawm daim ntawv penfil. Tus nqi ntawm cov tshuaj yuav txawv hauv khw muag khoom sib txawv. Ib qho ntxiv, kev hloov pauv kev hloov pauv ntawm cov txiaj ntsig cuam tshuam rau kev tsim cov nqi, vim qhov no yog tshuaj ntawm kev tsim khoom txawv teb. Yog li, tus nqi ntawm Actrapid cuam tshuam nkaus xwb rau hnub ntawm kev yuav khoom.
Cov tshuaj Insulin yog muab cia rau hauv tub yees kom deb ntawm lub tub yees ntawm qhov txias ntawm ob txog yim degrees. Koj tsis tuaj yeem khov nws. Lub raj mis qhib tuaj yeem khaws cia hauv chav sov li 6 lub lis piam, nco ntsoov tiv thaiv nws ntawm lub teeb thiab kub hauv cov thawv ntawv thawv. Cov yeeb yaj kiab hauv tsab xov xwm no yuav teb rau lo lus nug txog kev tswj hwm insulin.
Kev ua yeeb yam luv luv yog Actrapid insulin. Nws muaj raws li kev txhaj tshuaj thiab siv los kho hom 1 thiab ntshav qab zib hom 2, ntxiv rau kev kho mob kub ceev rau hyperglycemia. Tshwj xeeb feem ntau nws siv nyob rau hauv cov ntshav qab zib insulin-tiv thaiv. Cov neeg mob no xav tau cov tshuaj insulin mus ib sim. Txog kev tswj tau zoo ntxiv hauv cov ntshav qab zib cov ntshav, ntau hom tshuaj no ua ke. Thiab ib qho ntawm cov tshuaj ntawm kev xaiv yog Actrapid - insulin luv luv.
Cov yam ntxwv ntawm cov tshuaj
Cov tshuaj Insulin "Actrapid NM Penfill" yog kev daws teebmeem rau kev txhaj tshuaj. Cov tshuaj muaj nyob ntawm tib neeg pancreatic hormone tau los ntawm kev hloov kho noob. 1 ml ntawm cov tshuaj muaj 3.5 mg ntawm insulin. Ntxiv nrog rau nws, glycerin, zinc chloride thiab cov tshuaj tshwj xeeb yog yaj hauv dej rau kev txhaj tshuaj, tsim kom muaj qib xav tau ntawm cov kua qaub-lub hauv paus sib npaug. Cov tshuaj muaj nyob hauv cov ntawv tshwj xeeb rau ib rab koob 3 ml koob xoo. Qhov no yog cov koob tshuaj nruab nrab, tab sis qee kis nws yuav tsum nce nws.
Ntxiv nrog rau daim ntawv tso tawm no, muaj Insulin Actrapid NM hauv 10 ml vials. Nws tseem muaj tib neeg soluble hormone tau txais los ntawm kev siv tshuab engineering txoj kev. Muaj kuj yog ib qho tshuaj noj ntawm cov tshuaj - Actrapil MS. Nws siv tsawg dua, vim nws yog qhov nruab nrab uas muaj kab mob insulin.
Kev txiav txim ntawm cov tshuaj no
Kev siv tshuaj insulin nkag mus rau hauv lub hlwb thiab cuam tshuam cov txheej txheem metabolism, txhim kho kev thauj ntshav qab zib. Vim qhov no, qhov nqus ntawm nws cov ntaub so ntswg nce ntxiv. Glycogen synthesis hauv daim siab mob hlwb kuj yog kev ua kom lub siab thiab nce ntxiv. Insulin "Actrapid" yog hais txog kev siv yeeb yaj kiab luv luv. Nws cov txiaj ntsig hypoglycemic yuav txawv nyob ntawm tus qauv thiab qhov chaw ntawm kev txhaj tshuaj, kev noj tshuaj thiab kev ua neej ntawm tus neeg mob. Tab sis feem ntau, cov nyhuv ntawm cov tshuaj pib tom qab 30 feeb thiab kav mus txog 8 teev. Qhov siab tshaj plaws poob rau 2-3 teev tom qab qhia txog kev daws. Qhov siab nqus dej siab tshaj plaws muaj Actrapid NM, tshwj xeeb tshaj yog tias nws tau nkag mus rau qhov raug. Nws yog qhov zoo tshaj plaws los ua ib qho kev txhaj tshuaj rau ntawm daim tawv nqaij ntawm lub plab, yog li cov tshuaj yuav pib sai dua.
Cov kev thaiv tsis zoo thiab cov tshwm sim
Qee tus neeg mob muaj qee tus neeg tsis kam txais insulin rau tib neeg. Qee zaum qee qhov kev tsis haum tshuaj rau lwm cov tshuaj ntawm cov tshuaj kuj tseem yuav pom. Hauv cov rooj plaub no, lwm hom tshuaj insulin yog tus kho. Kev siv cov tshuaj yog tseem contraindicated nyob rau hauv cov ntaub ntawv ntawm hypoglycemia. Yog li, ua ntej kev qhia, nws yog ib qho tsim nyog yuav tau kuaj xyuas cov ntshav qab zib kom qis. Koj tuaj yeem siv tsis tau "Actrapid" rau mob qog nqaij hlav cancer - insuloma. Kev siv cov tshuaj no tsis yog sib kis rau cov menyuam yaus, thiab rau cov poj niam cev xeeb tub.
Thaum siv cov insulin "Actrapid", cov kev mob tshwm sim hauv qab no tuaj yeem tshwm sim:
Kev qhia ntawm cov kua dej "Actrapid"
Txoj kev ntawm kev coj ntawm cov tshuaj no yog, qee kis, mob pob leeg. Rau qhov no, cov koob tshuaj insulin tshwj xeeb xav tau. Lawv muaj qhov kawm tiav uas tso cai rau koj los ntsuas qhov nyiaj yog raug tshuaj. Feem ntau cov cwj mem tshwj xeeb rau cov kua dej "Actrapid NM" siv. Ua li no, kev txhaj tshuaj yog qhov yooj yim dua. Qhov kev txhaj tshuaj yuav tsum yog ua rau hauv plab lossis xub pwg, tsuas yog nyob hauv subcutaneous quav, zam kev txhaj tshuaj rau sab hauv. Qee zaum ib qho kev txhaj tshuaj yog txhaj rau hauv tus ncej puab lossis pob tw, tab sis hauv qhov no qhov tshuaj tau nqus tsis zoo.
Yuav ua li cas tswj hwm Actrapid insulin? Cov kev qhia piav qhia tus txheej txheem no raws li nram no:
- koj yuav tsum tau kos cov tshuaj txaus rau hauv cov phwj los ntawm lub raj mis los yog ntxig daim cartridge rau hauv tus cwj mem tshwj xeeb,
- nrog koj sab tes laug mus sau nrog ob tug ntiv tes ib daim tawv nqaij ntawm lub plab, ncej puab lossis xub pwg,
- nplaum lub rab koob rau hauv lub hauv paus ntawm quav ntawm lub kaum ntawm 45 degrees,
- maj mam txhaj cov tshuaj nyob rau hauv daim tawv nqaij,
- tawm rab koob li 5-6 feeb,
- ua tib zoo rub nws tawm, yog tias ntshav tawm los, koj yuav tsum nyem me ntsis ntawm qhov chaw txhaj tshuaj.
Insulin "Actrapid": cov lus qhia rau kev siv
Tsuas yog tus kws kho mob tuaj yeem txiav txim qhov xav tau ntau npaum li cas thiab kev siv ntau npaum li cas ntawm cov tshuaj. Nws nyob ntawm tus neeg mob cov zaub mov carbohydrate tus nqi, kev ua neej, kev noj zaub mov zoo thiab tshuaj insulin. Hauv nruab nrab, tsis pub ntau tshaj 3 ml yuav tsum tau nyob rau ib hnub, tab sis qhov ntsuas no yuav loj dua rau cov neeg rog, thaum cev xeeb tub lossis nrog kev tiv thaiv cov nqaij mos. Yog tias tus txiav ua tiav qhov tsawg kawg ntawm kev siv tshuaj insulin, nws yuav tsum tau muab rau hauv cov koob tshuaj kom tsawg dua. Qhov xav tau ntawm cov kua dej yog tseem txo hauv cov kab mob ntawm daim siab thiab lub raum.
Kev txhaj tshuaj ntawm "Actrapid" tau ua tiav 2-3 zaug hauv ib hnub. Yog tias tsim nyog, koj tuaj yeem nce ntau zaus ntawm kev siv txog li 5-6 zaug. Ib nrab ib teev tom qab kev txhaj tshuaj, koj yuav tsum noj lossis tsawg kawg muaj ib pluas noj nrog carbohydrates.
Nws yog qhov ua tau kom muab cov tshuaj no nrog cov tshuaj ntev. Piv txwv li, kev sib xyaw ua ke feem ntau yog siv: insulin "Actrapid" - "Protafan". Tab sis tsuas yog tus kws kho mob tuaj yeem xaiv ib tus kheej glycemic tswj kev ua haujlwm. Yog tias tsim nyog, nkag rau ob lub tshuaj insulin nyob rau tib lub sijhawm lawv sau rau hauv ib lub koob txhaj: thawj - "Actrapid", thiab tom qab ntawd - cov tshuaj insulin ntev ntev.
Yuav ua li cas thaum muaj ntshav qab zib
Qee qhov xwm txheej, feem ntau nrog kev noj ntau dhau, tus neeg mob txhim kho hypoglycemia. Nws tuaj yeem tshwm sim yog tias tom qab txhaj tshuaj tas tus neeg mob tsis tau noj los yog tau ua si lub cev ntau dhau.Tus mob no tshwm sim dheev. Tus neeg mob ntsib cov tsos mob li nram no:
- tachycardia
- xeev siab
- kev rhuav tshem dav dav, nkees nkees,
- hws
- kev ntxhov siab, ntxhov siab,
- mob taub hau
- muaj zog qab los noj mov
- tsis muaj kev sib koom ua ke ntawm txav.
Qhov pib ntawm hypoglycemia yog qhov yooj yim rau pom. Thawj yam ua yog noj yam qab zib. Rau qhov no, cov neeg mob ntshav qab zib ib txwm nqa khoom qab zib, ncuav qab zib, kua qab zib lossis ib qho qab zib nrog lawv. Yog hais tias tus neeg mob tus mob hnyav dua, nws muaj qhov tsis haum lossis tsaus muag, ib qho kev txhaj tshuaj ntawm glycogen yog qhov tsim nyog. Koj yuav tsum tau mus ntsib kws kho mob thiab kho qhov ntau dua ntawm Actrapid txhawm rau txhawm rau txhawm rau tiv thaiv kev txhim kho hypoglycemia.
Hyperglycemia thaum siv tshuaj
Qee zaum lwm qhov mob kuj tseem muaj peev xwm ua tau thaum cov piam thaj hauv ntshav nce siab. Qhov no tuaj yeem nrog qhov nce hauv qhov kub thiab txias, nrog cov kabmob sib kis, nrog rau qhov txo qis hauv cov tshuaj lossis nce ntxiv hauv qhov ntim ntawm cov khoom noj carbohydrate. tsis yog li hais, tab sis qhov mob kuj tseem txaus ntshai, vim nws tuaj yeem ua rau kev txhim kho ntawm ketoacidosis thiab coma. Qhov tseeb tias cov piam thaj tau nce siab tuaj yeem kwv yees los ntawm cov cim hauv qab no:
- nqhis dej heev
- nquag tso zis
- xeev siab, tsis qab los noj mov,
- tsis muaj zog
- qhuav ntawm daim tawv nqaij thiab cov qog ua kua,
- muaj zog tsw ntawm acetone los ntawm lub qhov ncauj.
Yog tias koj muaj ib qho ntawm cov tsos mob no, koj yuav tsum kuaj xyuas qib qab zib tam sim ntawd, koj yuav tsum tau txhaj tshuaj ntxiv rau Actrapid.
Cov Tshuaj Pharmacokinetics
Ib nrab-lub neej ntawm insulin los ntawm cov ntshav yog tsuas yog ob peb feeb.
Lub sijhawm ntawm kev ua ntawm insulin npaj feem ntau vim yog tus nqi ntawm kev nqus, uas nyob ntawm ntau yam (piv txwv, ntawm qhov koob tshuaj insulin, txoj kev thiab qhov chaw tswj hwm, qhov tuab ntawm subcutaneous rog txheej thiab hom mob ntshav qab zib mellitus). Yog li no, cov chaw muag tshuaj ntawm cov tshuaj insulin yuav raug rau qhov tseem ceeb nruab nrab- thiab kev hloov ntawm ib leeg ntawm ib leeg.
Qhov siab tshaj plaws (C max) ntawm cov tshuaj insulin hauv plasma tau tiav hauv 1.5-2.5 teev tom qab kev tswj hwm subcutaneous.
Tsis muaj cov lus tshaj tawm los txuas nrog cov ntshav plasma protein tau sau tseg, tsuas yog tshuav ntawm cov tshuaj tiv thaiv rau cov insulin (yog tias muaj).
Tib neeg cov kua dej muaj kev cuam tshuam los ntawm insulinase lossis insulin-cleaving enzymes, thiab tej zaum kuj yog los ntawm cov protein disulfide isomerase.
Nws tau kwv yees tias nyob rau hauv molecule ntawm tib neeg cov tshuaj insulin muaj ntau qhov chaw ntawm cleavage (hydrolysis), txawm li cas los xij, tsis muaj ib yam ntawm cov metabolites uas tau tsim los ntawm kev ua kom tsis muaj kev cuam tshuam.
Lub sijhawm ib nrab-nqus lub sijhawm (T ½) yog txiav txim siab los ntawm tus nqi ntawm nqus los ntawm cov nqaij mos subcutaneous. Yog li, T rather yog cov ntsuas ntawm kev nqus, dua li qhov ntsuas qhov tseeb ntawm kev tshem tawm cov insulin los ntawm ntshav (T ½ ntawm insulin los ntawm cov ntshav tsuas yog ob peb feeb). Kev tshawb fawb pom tias T ½ yog kwv yees 2-5 teev.
Menyuam yaus thiab tub ntxhais hluas
Daim ntawv qhia txog tus kws kho mob ntawm Actrapid-NM tau kawm nyob rau hauv pab pawg me ntawm cov menyuam yaus uas muaj ntshav qab zib mellitus (18 tib neeg) hnub nyoog 6-12 xyoo, nrog rau cov hluas (hnub nyoog 13-17 xyoo). Txawm hais tias cov ntaub ntawv tau txais los txiav txim siab tsawg, lawv txawm li cas los xij qhia tau tias qhov profile pharmacokinetic ntawm Actrapid-NM hauv cov menyuam yaus thiab cov hluas yog zoo ib yam li cov laus. Nyob rau tib lub sijhawm, kev sib txawv raug nthuav tawm ntawm cov hnub nyoog sib txawv los ntawm qhov ntsuas xws li C max, uas tau hais meej dua txog qhov xav tau ntawm kev xaiv koob tshuaj rau ib tug neeg.
Cov Ntaub Ntawv Muaj Kev Nyab Xeeb Ua Ntej
Hauv kev kawm ua ntej, nrog rau kev kawm txog kev nyab xeeb pharmacological, kev tshawb fawb tshuaj lom nrog kev rov qab ua dua, kev tshawb fawb ntawm genotoxicity, carcinogenic muaj peev xwm thiab muaj tshuaj lom rau ntawm tus kheej deev, tsis muaj kev pheej hmoo rau tib neeg tau txheeb xyuas.
Cev xeeb tub thiab lactation
Tsis muaj kev txwv txog kev siv cov tshuaj insulin thaum cev xeeb tub, vim tias cov tshuaj insulin tsis hla qhov chaw tiv thaiv.
Ob lub qog ntshav qab zib thiab hyperglycemia, uas tuaj yeem tsim kho thaum muaj kev xaiv tsis zoo, ua rau muaj kev pheej hmoo ntawm cov mis tsis ua haujlwm thiab kev tuag ntawm tus menyuam hauv plab. Cov poj niam cev xeeb tub uas muaj ntshav qab zib yuav tsum tau saib xyuas thoob plaws lub sijhawm lawv cev xeeb tub, lawv yuav tsum muaj kev tswj xyuas cov ntshav qabzib ntau ntau, cov lus qhia zoo ib yam rau cov poj niam uas npaj xeeb menyuam.
Qhov kev xav tau rau insulin feem ntau poob qis hauv thawj peb lub hlis thaum cev xeeb tub thiab maj mam nce ntxiv hauv qib thib ob thiab thib peb.
Tom qab yug menyuam, xav tau cov tshuaj insulin, raws li txoj cai, rov qab sai sai rau qib uas tau pom ua ntej muaj menyuam hauv plab.
Nws kuj tseem tsis muaj kev txwv rau kev siv tshuaj Actrapid ® NM lub sijhawm pub niam mis. Ua kev kho mob rau cov leej niam laus tsis muaj teeb meem rau tus menyuam. Txawm li cas los xij, tus niam yuav tsum tau kho qhov tshuaj ntau dua ntawm Actrapid ® NM thiab / lossis kev noj haus
Kho thaj chaw
Cov tshuaj muaj cov nyhuv kho tau sai, vim nws belongs rau pab pawg neeg pharmacological ntawm cov tshuaj tiv thaiv ua haujlwm sai. Cov khoom lag luam yog tsim los ntawm kev siv tshuab bioengineering ntawm cov khoom siv DNA sib xyaw nrog kev qhia txog kab lis kev cai ntawm baker lub poov xab. Tom qab kev tswj hwm ncaj qha ntawm cov tshuaj subcutaneously, cov tshuaj nquag pib sib cuam tshuam nrog cytoplasmic receptors hauv lub cell membrane. Cov tshuaj ua kom cov txheej txheem sab hauv ntawm tes los ntawm kev ua kom lub biosynthesis ntawm cAMP, uas tso cai rau nws nkag mus tob rau hauv qhov chaw ntawm tes.
Raws li cov lus qhia hauv radar qhia, qhov txo qis hauv cov ntshav qab zib yog tshwm sim los ntawm kev txav mus rau hauv lub cev ntau dua thiab nqus tau los ntawm lub cev nqaij, uas ua kom nrawm cia cov rog hauv lub cev, cov synthesis ntawm cov qauv protein, glycogenogenesis tshwm sim, nrog rau kev txo qis ntawm cov piam thaj los ntawm lub siab. Cov tshuaj pib ua haujlwm hauv lub cev ib nrab teev tom qab siv. Qhov siab tshaj plaws tau tiav tom qab 2.5 teev, thiab tag nrho lub sijhawm ua haujlwm yog li 7-8 teev.
Hla kev sib txuam yeeb tshuaj
Cov tshuaj uas pab txhim kho qhov ua tau zoo ntawm kev txo cov piam thaj: qhov ncauj tshuaj hypoglycemic, tshuaj anabolic steroids, androgens, ketoconazole, tetracycline, vitamin B6, bromocriptine, mebendazole, theophylline, tsis xaiv tshuaj beta-blockers, haus dej cawv, uas tsis tsuas yog txhim kho cov nyhuv, tab sis kuj ua kom ntev li ntawm kev ua.
Cov ntshav qab zib cov ntshav nce siab ntxiv: cov tshuaj tiv thaiv poj niam lub cev tiv thaiv kab mob hauv lub cev (cov tshuaj hluavtaws sib xyaw ntawm progesterone thiab estradiol), cov thyroid hormones, anticoagulants, clonidine, diazoxide, danazole, tricyclic antidepressants, calcium channel blockers, opioid analgesics, nicotinic acid thiab nicoteroids, Reserpine, salicylates, octreotide, lanreotide cuam tshuam rau cov hauj lwm zoo ntawm insulin tsis meej xwm. Cov tshuaj yeeb dej caw ob leeg tuaj yeem txo qis thiab nce qhov xav tau ntawm kev txiav txim siab ntawm cov tshuaj.
Thiols thiab sulfites ua rau muaj kev puas tsuaj lossis ua kom puas ntawm cov tshuaj, thiab beta-blockers ua rau muaj qhov tsis tseeb ntawm cov ntshav qog ntshav qab zib.
Qhia Txheej Txheem
Tso rau lwm tus, tso ntshav thiab tso ntshav tshuaj yog tso cai. Nrog rau kev tswj hwm subcutaneous, cov neeg mob tau qhia kom xaiv cov ncej puab thaj chaw rau kev txhaj tshuaj, nws nyob ntawm no tias cov tshuaj daws tau qeeb thiab tusyees.
Tsis tas li ntawd, koj tuaj yeem siv rau kev txhaj tshuaj lub pob tw, caj npab thiab sab xub ntiag ntawm phab ntsa ntawm lub plab (thaum txhaj rau hauv plab, cov nyhuv ntawm cov tshuaj pib sai li sai tau). Tsis txhob txhaj rau hauv ib thaj chaw ntau zaus dua ib hlis ib zaug, cov tshuaj yeeb yaj kiab tuaj yeem ua rau lipodystrophy.
Yog tias nws yog qhov tsim nyog los ua kom luv luv insulin nrog ntev, cov txheej txheem hauv qab no tau ua tiav:
- Huab cua yog nkag rau hauv ob qho tib si ampoules (nrog ob qho tib si luv thiab ntev),
- Ua ntej, tsub sij hawm luv luv insulin yog nqus mus rau hauv cov phwj, tom qab ntawd nws ntxiv nrog cov tshuaj ncua ntev,
- Cov huab cua tau tshem tawm los ntawm npuaj.
Cov neeg mob ntshav qab zib uas tsis tshua tau ntsib dua yog tsis pom zoo kom qhia Actropide rau hauv lub xub pwg ntawm lawv tus kheej, vim tias qhov kev pheej hmoo siab ntawm kev ua rau lub cev tsis muaj roj txaus-rog quav thiab txhaj tshuaj rau cov tshuaj intramuscularly. Nws yog tsim nyog sau cia tias thaum siv cov koob kom txog 4-5 hli, lub subcutaneous rog quav tsis tsim txhua.
Nws yog txwv tsis pub txhaj cov tshuaj rau hauv cov ntaub so ntswg hloov los ntawm lipodystrophy, thiab tseem mus rau qhov chaw ntawm hematomas, ntsaws ruaj ruaj, nti thiab nti.
Actropid tuaj yeem siv tau yog siv cov tshuaj insulin ua haujlwm, siv cov xaum xaum los yog lub tshuab nqus dej tsis siv neeg. Nyob rau hauv rooj plaub tom kawg, cov yeeb tshuaj tau qhia rau hauv lub cev ntawm nws tus kheej, hauv thawj ob nws tsim nyog los ua tus txheej txheem ntawm kev tswj hwm.
- Ib rab koob pov tseg raug ntsia,
- Cov tshuaj tau yooj yim tov, nrog kev pab ntawm dispenser 2 units ntawm cov tshuaj raug xaiv, lawv tau qhia rau hauv huab cua,
- Siv tus tes hloov, tus nqi ntawm cov koob xav tau raug teeb tsa,
- Daim ntawv rog ua cov roj ua rau ntawm daim tawv nqaij, raws li tau piav qhia hauv txheej txheem dhau los,
- Cov tshuaj tau qhia los ntawm nias lub piston txhua txoj kev,
- Tom qab 10 vib nas this, rab koob raug tshem tawm ntawm daim tawv nqaij, cov quav tso tawm.
Lub rab koob yog tsim nyog yuav tsum tau muab pov tseg.
Yog tias siv yeeb yam luv luv ua los siv, nws tsis tas yuav sib xyaw ua ntej siv.
Txhawm rau cais tawm qhov tsis haum ntawm cov tshuaj thiab qhov tshwm sim ntawm hypoglycemia, nrog rau hyperglycemia, insulin yuav tsum tsis txhob raug txhaj rau hauv thaj chaw tsis tsim nyog thiab kev noj tshuaj tsis pom zoo nrog kws kho mob yuav tsum tau siv. Kev siv cov tshuaj Actrapid uas tas sij hawm yog txwv tsis pub, cov tshuaj yuav ua rau muaj kev tiv thaiv ntau dhau ntawm cov tshuaj insulin.
Kev tswj hwm ntawm cov leeg lossis intramuscularly tsuas yog ua los ntawm kev saib xyuas ntawm tus kws kho mob koom xwb. Actrapid nkag tau rau hauv lub cev ib nrab teev ua ntej noj mov, zaub mov yuav tsum muaj cov khoom noj carbohydrates.
Cov lus qhia: nws zoo dua rau kev txhaj tshuaj insulin nyob rau hauv chav tsev kub, yog li qhov mob los ntawm kev txhaj tshuaj yuav tsis tshua pom kev.
Ua li cas yog Actrapid
Insulin Actrapid yog koom nrog cov pab pawg tshuaj uas lawv ua tseem ceeb yog txhawm rau txo cov ntshav qab zib kom tsawg. Nws yog yeeb tshuaj luv-luv.
Qab zib txo yog vim:
Qhov ntsuas thiab ceev npaum li cas ntawm cov tshuaj muaj yees nyob ntawm ntau yam:
- Muab cov insulin npaj,
- Txoj kev ntawm cov thawj coj (koob txhaj, koob txhaj tshuaj, twj tso kua mis),
- Qhov chaw xaiv rau kev tswj hwm tshuaj (plab, caj npab, ncej puab lossis pob tw).
Nrog rau kev coj ua ntawm subrapaneous ntawm Actrapid, cov tshuaj pib ua tom qab 30 feeb, nws nce mus txog nws qhov siab tshaj plaws hauv lub cev tom qab 1-3 teev, nyob ntawm tus neeg qhov yam ntxwv ntawm tus neeg mob, thiab cov nyhuv hypoglycemic yog nquag ua haujlwm rau 8 teev.
Siv thaum cev xeeb tub
Kev siv tshuaj kho tus mob yog tau tso cai thaum cev xeeb tub ntawm tus neeg mob. Thoob plaws lub sijhawm, nws yog ib qhov tsim nyog los tswj cov piam thaj thiab hloov cov tshuaj noj. Yog li, nyob rau thawj lub hlis thib ib, xav tau cov tshuaj tsawg dua, nyob rau zaum ob thiab thib peb - ntawm qhov tsis sib xws, nws nce.
Tom qab yug menyuam tas, xav tau cov tshuaj insulin tau rov qab los rau hauv qib uas yog ua ntej cev xeeb tub.
Thaum lub sijhawm lactation, yuav txo qhov ntau npaum yuav tsim nyog. Tus neeg mob yuav tsum tau ua tib zoo soj ntsuam cov ntshav qab zib kom tsis txhob plam lub sijhawm thaum xav tau cov tshuaj nyob ruaj khov.
Yuav thiab khaws cia
Koj tuaj yeem yuav Actrapid hauv khw muag tshuaj raws li kws kho mob sau ntawv yuav.
Nws yog qhov zoo tshaj plaws los khaws cov tshuaj rau hauv lub tub yees ntawm qhov kub ntawm 2 txog 7 degrees Celsius. Tsis txhob cia cov khoom raug nthuav tawm ncaj qha rau tshav kub lossis tshav ntuj. Thaum khov, Actrapid poob nws cov suab thaj txo qis tus yam ntxwv.
Ua ntej kev txhaj tshuaj, tus neeg mob yuav tsum kuaj xyuas lub sijhawm siv tshuaj, kev siv cov tshuaj insulin tsis pub dhau sijhawm. Nco ntsoov xyuas cov ampoule lossis vial nrog Actrapid rau kev zas thiab txawv tebchaws.
Actrapid yog siv los ntawm cov neeg mob uas muaj ob hom 1 thiab hom 2 mob ntshav qab zib mellitus Cov. Nrog rau kev siv kom zoo thiab ua raws nrog cov tshuaj uas qhia los ntawm tus kws kho mob, nws tsis ua rau muaj kev txhim kho kev mob tshwm sim hauv lub cev.
Nco ntsoov tias cov ntshav qab zib yuav tsum tau kho kom to taub: ntxiv rau kev txhaj tshuaj txhua hnub, koj yuav tsum ua raws li qee yam kev noj zaub mov, saib xyuas lub cev ua si thiab tsis ua rau lub cev muaj kev ntxhov siab.
Kev kho mob ntawm cov neeg mob uas muaj ntshav qab zib hom 1 tau ua hauv daim ntawv ntawm kev hloov tshuaj insulin. Ua ke nrog kev txwv kev noj zaub mov, kev tswj hwm insulin tuaj yeem tiv thaiv cov neeg mob no los ntawm kev mob hnyav ntshav qab zib.
Thaum sau tshuaj rau hauv insulin, nws yog qhov yuav tsum tau sim kom yug cov menyuam ze ze li qhov ua tau rau lub ntuj sib luag ntawm nws qhov kev nkag mus rau hauv cov ntshav. Rau qhov no, ob hom tshuaj insulin feem ntau qhia rau cov neeg mob - ntev thiab luv.
Lub sijhawm ntev insulins mimic qab nthab (cov menyuam me) zais cia. Cov insulins luv luv tau hais tseg rau qhov nqus ntawm carbohydrates los ntawm cov khoom noj. Lawv muab ua ntej noj mov hauv ib qho koob tshuaj sib xws nrog cov naj npawb ntawm cov khob cij hauv cov khoom. Actrapid NM belongs rau cov insulins xws.