Tujo SoloStar® Insulin Glargine > Kev khomob thiab kev tiv thaiv

Kev daws rau kev txhaj tshuaj 300 IU / ml, 1.5 ml

1 ml ntawm cov tshuaj muaj:

cov tshuaj heev - insulin glargine 300 PIECES,

zam txim: meta-cresol, zinc chloride, glycerin (85%), sodium hydroxide, hydrochloric acid, dej rau kev txhaj tshuaj

Cov ntshiab, tsis muaj kob uas daws tsis pom cov khoom siv ua rau lub cev tsis haum.

Cov chaw muag tshuaj

Cov Tshuaj Pharmacokinetics

Kev nqus thiab faib khoom

Nyob rau hauv cov neeg tuaj yeem noj qab haus huv thiab cov neeg mob ntshav qab zib mellitus, tom qab subcutaneous txhaj ntawm Tujeo SoloStar®, cov tshuaj insulin nyob rau hauv cov ntshav cov ntshav qhia tau qeeb qeeb thiab ntev dua nqus piv rau cov tshuaj insulin glargine 100 IU / ml, uas ua rau lub ntsej muag sib txawv ntawm lub sijhawm.

Cov tshuaj Pharmacokinetic profiles muaj raws nraim nrog cov chaw muag tshuaj ua haujlwm ntawm Tujeo SoloStar®.

Kev sib zog ua kom tiav nyob rau hauv kev kho kom zoo ntau yam yog ua tiav tom qab 3-4 hnub ntawm kev tswj hwm txhua hnub ntawm cov tshuaj Tujo SoloStar®.

Tom qab kev txhaj tshuaj ntawm Tujeo SoloStar® txhaj tshuaj sib txawv, qhov hloov pauv ntawm cov kabmob xaim hluav taws xob rau 24 xuaj moos nyob rau hauv lub xeev ntawm kev ua tiav cov tshuaj lom hauv tib lub siab tus neeg mob yog qhov tsawg (17.4%).

Tom qab txhaj tshuaj subcutaneous, insulin glargine yog sai metabolized los tsim ob lub zog metabolites, M1 (21A-Gly-insulin) thiab M2 (21A-Gly-des-30B-Thr-insulin). Hauv cov ntshav ntshav, lub ntsiab lus nthuav tawm ntawm cov ntshav yog cov metabolite M1.

Qhov kev cuam tshuam ntawm M1 metabolite nce nrog qhov nce ntxiv ntawm kev muab tshuaj ntau dua ntawm insulin glargine. Cov kev tshawb fawb ntawm pharmacokinetics thiab pharmacodynamics qhia tau hais tias kev txiav txim ntawm subcutaneous insulin glargine txhaj tshuaj feem ntau vim yog raug M1. Hauv feem coob ntawm cov neeg mob nws tsis tuaj yeem kuaj txog insulin glargine thiab metabolite M2, thiab yog tias thaum lawv tuaj yeem raug txiav txim siab, lawv qhov kev cia siab tsis yog nyob ntawm qhov kev muab tshuaj thiab cov tshuaj noj tshuaj ntawm insulin glargine.

Tom qab kev tswj hwm zoo, ib nrab ntawm lub neej ntawm insulin glargine thiab insulin tib neeg tau sib piv. Ib nrab-lub neej tom qab subcutaneous kev tswj hwm ntawm cov tshuaj Tujo SoloStar® yog txiav txim siab los ntawm tus nqi ntawm kev nqus ntawm cov nqaij mos subcutaneous. Ib nrab-lub neej ntawm Tujeo SoloStar® tom qab kev tswj hwm subcutaneous yog 18-19 teev thiab tsis yog nyob ntawm seb cov koob tshuaj.

Cov Tshuaj Hauv Tshuaj

Kev ua haujlwm tseem ceeb ntawm insulin, suav nrog insulin glargine, yog kev cai ntawm cov metabolism hauv cov piam thaj. Cov tshuaj Insulin thiab nws cov tshuaj noj kuj txo cov ntsiab lus ntawm cov ntshav qabzib los ntawm kev ua kom nqus tau cov ntshav qabzib los ntawm peripheral cov ntaub so ntswg, tshwj xeeb hauv cov leeg nqaij thiab adipose cov nqaij, nrog rau los ntawm inhibiting tsim cov piam thaj hauv lub siab. Cov tshuaj insulin inhibits lipolysis hauv adipocytes, inhibits proteolysis thiab txhim kho cov protein synthesis.

Glulin insulin yog ib qho piv txwv ntawm tib neeg cov insulin tsim kom muaj solubility qis ntawm pH nruab nrab. Ntawm pH 4, insulin glargine yog soluble kiag li. Tom qab txhaj tshuaj rau hauv cov nqaij mos subcutaneous, cov kua tshuaj acidic yog nruab nrab, uas ua rau cov neeg muaj dej sai sai, los ntawm cov kua dej me me ntawm cov tshuaj insulin glargine tso tawm tsis tu ncua. Raws li pom nyob rau hauv cov kev tshawb fawb siv euglycemic clamp txoj kev koom nrog cov neeg mob uas muaj ntshav qab zib hom 1, cov piam thaj-txo cov nyhuv ntawm cov tshuaj Tujo SoloStar® tau nyob tas mus li thiab ntev dua li piv nrog insulin glargine 100 IU / ml tom qab lawv cov subcutaneous tswj hwm. Qhov kev txiav txim ntawm cov tshuaj Tujo SoloStar® tau siv sijhawm ntev dua 24 teev (txog 36 teev) ntawm cov chaw txhaj tshuaj uas muaj feem cuam tshuam. Hauv kev tshawb nrhiav tshuaj thiab pharmacological, kev muab tshuaj rau insulin glargine thiab tshuaj insulin rau tib neeg ua pov thawj tias muaj qhov sib luag yog tias siv tib zaug. Ib yam li lwm yam insulins, lub sijhawm sijhawm ntawm insulin glargine tuaj yeem cuam tshuam los ntawm kev ua haujlwm ntawm lub cev thiab lwm yam kev hloov pauv.

Cov chaw kuaj mob tau zoo thiab Kev Nyab Xeeb

Kev ua hauj lwm tag nrho thiab kev nyab xeeb ntawm Tujeo SoloStar® (insulin glargine 300 IU / ml) ib hnub ib zaug rau kev tswj glycemic tau muab piv nrog cov ntawm insulin glargine 100 IU / ml ib zaug ib hnub hauv kev qhib, kev soj ntsuam kev sib tw hauv cov pawg sib txuas nrog cov kev tswj nquag tau mus txog 26 lub lis piam, suav nrog 546 cov neeg mob ntshav qab zib hom 1 thiab 2474 cov neeg mob ntshav qab zib hom 2.

Cov txiaj ntsig tau hauv txhua qhov kev soj ntsuam nrog Tujeo SoloStar® tau qhia tias qhov txo qis ntawm glycated hemoglobin HbA1c tus nqi piv rau qhov pib tus nqi los ntawm qhov kawg ntawm txoj kev tshawb no tsis qis dua qhov ntawd nrog kev tswj hwm ntawm insulin glargine 100 IU / ml. Qhov feem pua ntawm cov neeg mob uas ua tiav lub hom phiaj HbA1c (qis dua 7%) zoo sib xws hauv ob pawg kho mob.

Qhov kev txo qis ntshav ntshav nyob rau thaum kawg ntawm txoj kev tshawb fawb nrog Tujeo SoloStar® tau zoo ib yam li ntawd nrog insulin glargine 100 IU / ml muaj qhov txo qis zuj zus ntxiv thaum lub sijhawm them nyiaj nrog kev qhia txog Tujeo SoloStar®. Kev tswj hwm Glycemic zoo sib xws nrog kev tswj hwm ntawm Tujeo ib hnub ib zaug thaum sawv ntxov lossis thaum yav tsaus ntuj.

Txhim kho hauv HbA1c tsis yog nyob ntawm poj niam txiv neej, haiv neeg, hnub nyoog, lossis sijhawm mob ntshav qab zib (

Tujo SoloStar

Cov tshuaj Tujeo yog tsim los ntawm lub tuam txhab German Sanofi. Nws tau tsim nyob rau hauv lub hauv paus ntawm glargine, uas hloov nws mus rau lub caij nyoog-tso tawm cov kua dej ntev ntev, muaj peev xwm tswj tau cov ntshav qab zib kom zoo, tiv thaiv nws qhov hloov sai. Tujeo yuav luag tsis muaj kev mob tshwm sim, thaum muaj cov ntsiab lus muaj zog them taus. Teeb meem thiab qhov tsis xav tau nyob ntawm cov leeg poob siab thiab hlab plawv tuaj yeem zam tau. Tujeo yog qhov tsim nyog rau kev kho mob ntawm hom 1 thiab ntshav qab zib hom 2.

Pharmacodynamics thiab pharmacokinetics

Tujeo yog cov tshuaj ntawm cov tshuaj insulin, tau los ntawm kev rov ua kom tiav cov kab mob DNA. Lub cev tseem ceeb ntawm insulin yog los tswj lub cev kev noj zaub mov kom qabzib. Nws txo cov ntshav qabzib ntau ntau, nce nws kev nqus hauv adipose cov nqaij thiab cov pob txha pob txha, ua kom muaj protein ntau, inhibits daim siab ua haujlwm siab thiab lipolysis hauv cov roj ntsha. Cov txiaj ntsig ntawm kev siv ntawm cov tshuaj Tujo SoloStar qhia tau hais tias muaj lub zog nqus ntev, siv sijhawm ntev txog 36 teev.

Piv rau glargine 100, cov tshuaj qhia pom softer concentration-sijhawm nkhaus. Lub sijhawm nruab hnub tom qab txhaj tshuaj ntu ntawm Tujeo, qhov sib txawv yog 17.4%, uas yog qhov ntsuas qis. Tom qab txhaj tshuaj, cov tshuaj insulin glargine yauv kom muaj cov metabolism nrawm nrawm thaum lub sij hawm tsim los ntawm kev sib koom tes ntawm cov kev sib txuas tshwj xeeb M1 thiab M2. Cov ntshav plasma hauv qhov no muaj qhov ntau dua nrog lub metabolite M1. Ua kom lub koob zuj zus ua rau muaj qhov nce ntxiv hauv qhov kev tiv thaiv mob hauv lub cev ntawm cov tshuaj metabolite, uas yog lub hauv paus tseem ceeb hauv kev txiav txim ntawm cov tshuaj.

Kev siv tshuaj insulin

Kev tswj hwm hauv qab plab, hips thiab caj npab. Qhov chaw txhaj tshuaj yuav tsum tau hloov pauv txhua hnub txhawm rau tiv thaiv qhov tsim ntawm nti thiab kev puas tsuaj rau cov ntaub so ntswg subcutaneous. Taw qhia ntawm cov leeg ntshav tuaj yeem ua rau muaj mob ceev ceev ntawm hypoglycemia. Cov tshuaj muaj qhov ua kom ntev ntev yog tias txhaj tshuaj nyob hauv qab daim tawv. Kev noj tshuaj ntawm cov tshuaj insulin yog nqa tawm los ntawm kev siv rab koob txhaj tshuaj, kev txhaj tshuaj muaj txog li 80 units. Nws yog qhov ua tau kom nce lub koob thaum lub sij hawm siv tus cwj mem hauv nce ntxiv ntawm 1 ib chav.

Tus cwj mem yog tsim los rau Tujeo, uas tshem tawm qhov kev xav tau ntawm kev rov muab cov tshuaj ntau npaum. Cov koob txhaj ib txwm siv tau tuaj yeem rhuav tshem daim cartridge nrog kev siv tshuaj thiab yuav tsis tso cai rau koj los ntsuas qhov tseeb ntawm koob tshuaj insulin. Lub koob txhaj tshuaj pov tseg thiab yuav tsum tau hloov nrog txhua txoj kev txhaj tshuaj. Cov koob txhaj tshuaj ua haujlwm tau zoo yog tias poob ntawm cov insulin tshwm rau qhov taub ntawm rab koob. Qhia txog qhov ua kom tsawg ntawm cov insulin koob txhaj tshuaj, muaj kev phom sij ntawm kev txhaws lawv thaum siv theem ob, uas yuav tsis tso cai rau tus neeg mob tau txais cov koob tshuaj insulin. Tus cwj mem tuaj yeem siv tau rau ib hlis.

Cov lus qhia tshwj xeeb

Cov neeg mob ntshav qab zib yuav tsum tau saib xyuas lawv cov ntshav qabzib hauv siab, tuaj yeem ua rau cov tshuaj hno ntshav qab zib kom raug, thiab nres ntshav qab zib thiab hyperglycemia. Tus neeg mob yuav tsum yog nws tus neeg zov nws txhua lub sijhawm, soj ntsuam nws tus kheej thaum kho cov tshuaj insulin rau qhov tshwm sim ntawm cov mob no. Cov neeg mob uas tau mob raum tsis ua haujlwm yuav tsum paub tias yuav tsum muaj qee yam tshuaj hormones vim qee zaum qis vim tias muaj peev xwm ua rau cov metabolism hauv insulin tsawg zuj zus thiab muaj peev xwm txo qis gluconeogenesis.

Kev sib cuam tshuam txog yeeb tshuaj

Qee cov tshuaj yuav cuam tshuam cov metabolism hauv cov piam thaj. Yog tias lawv tau noj ua ke nrog cov tshuaj hormones, tom qab ntawd nws yuav tsim nyog qhia meej qhov koob tshuaj. Ntawm cov tshuaj uas tuaj yeem ua rau cov ntshav qog ntshav ntau ntawm cov tshuaj insulin thiab pab txhawb qhov pib ntawm hypoglycemia yog Fluoxetine, Pentoxifylline, tshuaj tua kabmob sulfonamide, fibrates, ACE inhibitors, MAO inhibitors, Disopyramide, Propoxyphene, salicylates. Yog tias koj noj cov nyiaj no nyob rau tib lub sijhawm xws li glargine, koj yuav tsum tau hloov tshuaj ntau dua.

Lwm yam tshuaj tuaj yeem ua rau cov ntshav qab zib hauv lub ntsej muag tsis muaj zog. Ntawm lawv yog Isoniazid, glucocorticosteroids, kev loj hlob hormone, protease inhibitors, tshuaj nrog phenothiazine, Glucagon, sympathomimetics (Salbutamol, Terbutaline, Adrenaline), estrogens thiab progestogens, suav nrog cov uas muaj nyob hauv cov tshuaj tiv thaiv qog, cov thyroid hormones, atyroid gland, diurethane, tshuaj tiv thaiv kev mob hlwb (clozapine, olanzapine), diazoxide.

Thaum siv ua ke nrog kev npaj nrog ethanol, clonidine, lithium ntsev los yog beta-blockers, cov nyhuv hormone yuav nce thiab ua neeg tsis muaj zog. Concurrent siv nrog Pentamidine tuaj yeem ua rau lub qog ntshav qab zib, feem ntau hloov mus rau hyperglycemia. Kev siv cov pioglitazone ua ke nrog cov tshuaj hormones hauv qee qhov teeb meem tuaj yeem ua rau kom tsis txhob muaj lub plawv nres.

Cov kev thaiv tsis zoo thiab cov tshwm sim

Cov tshuaj yuav tsum tsis txhob siv yog tias muaj ib tus neeg tsis kam txais rau cov khoom siv. Tujeo yog tsim rau cov neeg laus xwb. Ceev faj yuav tsum siv rau hauv cov poj niam cev xeeb tub, cov neeg uas muaj mob endocrine thiab muaj hnub nyoog so hauj lwm. Tujeo tsis haum rau cov kab mob ntshav qab zib ketoacidosis. Cov kev mob tshwm sim tshwm sim suav nrog:

kev fab tshuaj tsis haum
ua yeeb yaj kiab
hnyav
pom kev pom
myalgia
ntshav qog.

Cov nqe lus ntawm kev muag khoom thiab kev cia khoom

Cov tshuaj yog muab rau hauv cov tsev muag tshuaj nrog cov tshuaj noj. Nws yog qhov tsim nyog yuav tsum tau muab rau hauv qhov chaw tiv thaiv los ntawm lub teeb, qhov kub yuav tsum nyob nruab nrab ntawm 2-8 ° C. Nkaum ntawm cov menyuam yaus. Thaum khaws cov tshuaj, nws yog ib qho tseem ceeb kom ntseeg tau tias cov khoom ntim ntawm cov npiv tsis nkag rau hauv lub thawv txias, vim tias cov tshuaj insulin tsis tuaj yeem khov. Tom qab siv thawj zaug, khaws cov tshuaj tsis pub dhau 4 lub lis piam.

Cov Khoom Ntawm Insulin Tujeo

Qhov zoo ntawm cov tshuaj hla analogues yog pom tseeb. Qhov no yog qhov ua kom ntev (hauv 24-35 teev), thiab noj tsawg, thiab muaj kev tswj cov ntshav qab zib kom ntau (txawm tias muaj tsawg dua qhov kev txhaj tshuaj), thiab kev txhaj tshuaj tsis tuaj yeem ua raws cai. Ntawm cov qauv analogues ntawm basal insulin ntawm ib tiam tshiab:

Nqe rau Insulin Tujeo

Hauv tebchaws Russia, Tujeo tuaj yeem nrhiav dawb, nws raug faib tawm nruj raws li kws kho mob sau tseg. Koj tuaj yeem yuav hauv khw muag tshuaj lossis hauv kiab khw online rau cov neeg mob ntshav qab zib. Tus nqi nruab nrab yog 3100 rubles, qhov tsawg kawg yog 2800 rubles.

Maria, 30 xyoo lawm Kuv nyiam cov tshuaj insulin ntev ntev, Kuv tau siv cov tshuaj no ntau tshaj li ib xyoos tam sim no. Muaj siv los ua Tresiba. Qhov loj tshaj plaws yog tias tsis muaj kev pheej hmoo ntawm hypoglycemia, tom qab cov kab mob insulin yav dhau los muaj qhov tsis zoo tsis txaus ntseeg. Kuv tsis nco qab txog cov dhia hauv qab zib, Tujeo ua kom lub luag haujlwm zoo li qub. Kuv tsis pom tseem xav tau khoom noj txom ncauj. Kev txhaj tshuaj tiav tau yooj yim, koj yuav tsis yuam kev nrog qhov muab tshuaj.

Victor, 43 xyoo. Kuv xav tau ib qho kev txhim kho ntawm hypoglycemia tom qab siv cov tshuaj tresib. Tus kws endocrinologist tau qhia txog lub lantus tujeo. Rau rau lub hlis tam sim no kuv tsis paub teeb meem, txawm tias poob ceeb thawj. Kuv nyiam tias koj tsis tas yuav hno tshuaj ntau ntau, cov yeeb tshuaj ua haujlwm hauv lub cev ntev. Nws yog ib qho tseem ceeb uas lub koob txhaj tshuaj yooj yim uas ntsuas qhov tseeb ntawm cov tshuaj.

Rosie, 24 xyoos Tujeo tau siv nws rau ib lub lim tiam. Nws tau ntoo khaub lig ntshai. Kuv tau muaj ntshav qab zib hom 1 tau ntev, thiab tsis muaj lub siab xav sim. Yav tas los siv Lantus. Hauv kev sib txuas nrog kev hloov pauv, Kuv tsis tau pom cov kev hloov pauv, tab sis nrog Tujeo lub siab hypo dhia thaum hmo ntuj nres, Kuv xav noj tsawg dua. Kuv pom zoo kom Tujeo ua qhov zoo tshaj plaws thiab niaj hnub ua cov insulin.

Pharmacological kev txiav txim

Hais txog cov neeg sawv cev hypoglycemic. Vim yog cov kev ua haujlwm ntawm insulin, cov txheej txheem hauv kev zom zaub mov hauv qabzib yog tswj hwm. Qhov concentration ntawm cov piam thaj hauv cov ntshav yog txo vim nws qhov nqus tau zoo hauv cov leeg nqaij thiab cov nqaij mos adipose. Hauv qhov no, kev tsim cov tshuaj polysaccharide ntau hauv cov nplooj siab yog inhibited, thiab cov synthesis ntawm cov qauv protein ntau nce.

Cov tshuaj muaj nyob rau hauv daim ntawv ntawm cov tshuaj tiv thaiv kom haum rau kev txhaj tshuaj hauv qhov ntim ntawm 1.5 ml.

Cov Tshuaj Pharmacokinetics

Muab piv nrog cov tshuaj insulin luv luv, tom qab txhaj tshuaj ntawm cov tshuaj no, cov khoom ua kom nquag plias yog nqus tau los ntawm cov nqaij mos subcutaneous qeeb dua. Qhov siab tshaj plaws ntawm cov tshuaj nquag nyob hauv cov ntshav raug pom 2 teev tom qab txhaj tshuaj. Nws yog metabolized feem ntau hauv lub siab. Nws yog tawm hauv cov qauv ntawm cov khoom noj khoom haus yooj yim. Ib nrab-lub neej yog li 19 teev.

Kev ntsuas rau siv

Kev siv cov tshuaj no raug pom zoo hauv kev kho mob txhua yam mob ntshav qab zib hauv cov neeg laus.

Yuav ua li cas noj Tujeo?

Nws raug nquahu kom txhaj rau tib lub sijhawm 1 zaug nyob rau ib hnub. Yog tias yuav tsum tau txhaj ib zaug, ces kev txhaj tshuaj tuaj yeem ua tiav thaum twg los tau ntawm lub hnub. Yog tias nws tsis tuaj yeem tso cov kev txhaj tshuaj tib lub sijhawm, nws raug nquahu kom ua qhov txheej txheem ua ntej 3 teev ua ntej lossis tom qab lub sijhawm teem sijhawm. Kev ua ntawm cov tshuaj yuav tsum txaus rau ib hnub nkaus.

Yuav ua li cas los xam cov koob tshuaj?

Hauv kev kho mob ntshav qab zib hom 1, hno tau pom zoo nrog pluas noj. Nws yuav tsum tau yug los hauv lub siab tias qhov tsuas tshuaj yog xaiv rau txhua tus neeg mob ib tus zuj zus, tab sis yuav tsum tsis txhob ntau tshaj 100 units hauv ib hnub. Rau cov txiaj ntsig zoo tshaj, cov tshuaj tau ua ke nrog lwm cov insulins luv luv ua yeeb yam.

Nws raug nquahu kom txhaj rau tib lub sijhawm 1 zaug nyob rau ib hnub. Yog tias yuav tsum tau txhaj ib zaug, ces kev txhaj tshuaj tuaj yeem ua tiav thaum twg los tau ntawm lub hnub.

Txog kev kho mob ntshav qab zib hom 2, tshuaj txhua hnub yog ntau dua 200 units. Yog hais tias tus neeg mob tsis txaus, nws tuaj yeem ua ke nrog lwm tus neeg sawv cev uas muaj cov nyhuv hypoglycemic.

Yuav siv tus cwj mem syringe li cas?

Koj tsis tuaj yeem nkag mus rau cov tshuaj ua ke. Qhov no tuaj yeem ua rau cov tshuaj insulin tsis sib haum nrog lwm cov tshuaj thiab ua rau muaj ntshav qab zib tsawg. Txhaj tshuaj tau ua tsuas yog hauv cov roj ntsha subcutaneous.

Daim duab syringe yog tau npaj ua ntej nrog kev daws thiab 1 rau 80 chav nyob ntawm cov tshuaj raug muab tshuaj. Hauv qhov no, qhov nce ntxiv yuav tsum tsis pub ntau tshaj 1 chav tsev. Lub koob txhaj tshuaj puv lawm tsim tshwj xeeb rau kev taw qhia ntawm Toujeo SoloStar, yog li tsis muaj qhov muab tshuaj ntxiv xav tau.

Cov tshuaj yuav tsum tsis txhob hloov los ntawm kev txhaj tshuaj hauv qhov quav mus rau lwm qhov koob txhaj tshuaj. Qhov no tuaj yeem ua rau muaj kev txwv ntau dhau. Koob rau txhua txoj kev txhaj tshuaj raug tso nrog tshiab. Lawv yuav tsum ua kom tsis muaj menyuam.

Ua ntej koj pib siv cov phwj syringe, koj yuav tsum ua tib zoo kawm cov lus qhia rau kev siv, uas yuav tsum muaj nyob hauv thawj ntim. Yuav kom muaj kev nyab xeeb ntau dua thaum txhaj tshuaj yuav tsum tsis tsuas hloov cov koob txhua zaus. Nco ntsoov tias daim phuam yog siv los ntawm ib tug neeg xwb.

Ntawm ib feem ntawm cov metabolism thiab khoom noj khoom haus

Kev nce siab tsis nco qab tshwm sim, tus neeg mob ib txwm xav tias tshaib plab. Tus mob no tuaj yeem ua rog rog tau. Vim tias kev txhim kho hypoglycemia, cov metabolism hauv zuj zus, uas ua rau kom cov ntshav qab zib tsawg dua vim tias cov piam thaj hauv cov metabolism. Kev ua kom rog cov roj thiab rog rog kuj tseem yuav tsis zoo.

Kev phiv los sis yeeb tshuaj yuav ua rau muaj kev mob plab zom mov.
Kev phiv los sis cov tshuaj yuav rog.
Qhov tshwm sim phiv los ntawm cov tshuaj yuav yog myalgia.
Kev phiv los ntawm cov tshuaj yuav yog qhov nce ntxiv ntawm lub siab.

Ntawm ib sab ntawm daim tawv nqaij

Cov tshuaj tiv thaiv hauv zos tshwm sim ntawm cov chaw txhaj tshuaj. Qhov mob, ua xeb, ua tawv nqaij liab thiab kub tau sau tseg.

Feem ntau nrog kev siv cov insulin ntev ntev, kev ua xua tshwm sim. Lawv pom los ntawm cov tawv nqaij tshwj xeeb ua pob, khaus thiab kub. Urticaria thiab Quincke's edema yuav tshwm sim.

Kev phiv los ntawm cov tshuaj tuaj yeem ua pob khaus thiab khaus.
Kev phiv los sis yeeb tshuaj yuav plooj tsis pom kev.
Kev phiv los sis yeeb tshuaj yuav yog Quincke's edema.
Qhov tshwm sim tsis zoo ntawm cov tshuaj yuav tuaj yeem tsim kev foob ntawm qhov chaw txhaj tshuaj.

Siv thaum cev xeeb tub thiab lactation

Nws raug pom zoo los siv thaum lub sijhawm sib deev. Hauv kev tshawb fawb, tsis muaj qhov tshwm sim tsis zoo ntawm cov tshuaj txuam ntawm cov tshuaj ntawm tus menyuam hauv plab. Qhov xav tau rau insulin tsawg zuj zus thaum pib cev xeeb tub, thiab thaum kawg, ntawm qhov tsis tooj, nce ntxiv. Yog li, txhawm rau txhawm rau tiv thaiv kev txhim kho ntawm hyperglycemia, nws yog ib qho tsim nyog yuav tsum tau saib xyuas tas li ntawm cov piam thaj hauv cov ntshav ntawm tus poj niam cev xeeb tub.

Tom qab yug menyuam thiab lub sijhawm pub niam mis, xav tau cov tshuaj insulin txo qis, yog li, kev hloov tshuaj ntau dua yuav tsum tau ua.
Hauv raum tsis ua haujlwm, insulin metabolism qeeb, thiab yog li ntawd lub cev qhov xav tau rau nws yog qee qhov qis.
Koj tsis tuaj yeem muab cov tshuaj no nrog cov cawv muaj cawv.
Nws tsis raug tso cai rau kho cov menyuam yaus nrog cov tshuaj zoo li no.
Nws raug siv los siv cov tshuaj thaum lub sijhawm cev xeeb tub.

Tom qab yug menyuam thiab lub sijhawm pub niam mis, xav tau cov tshuaj insulin txo qis, yog li, kev hloov tshuaj ntau dua yuav tsum tau ua.

Siv rau lub sijhawm qub

Rau cov neeg mob uas muaj hnub nyoog 65 xyoos, qhov pib thiab kev tu tus neeg siv yuav tsum muaj tsawg heev. Txoj kev pheej hmoo ntawm kev txhim kho mob latent hypoglycemia yog nce. Tsis tas li ntawd, lwm qhov kev tiv thaiv hypoglycemic cuam tshuam nrog kev sib txuas ntxiv ntawm cov insulin feem ntau txhim kho. Yog li, cov tshuaj hloov kho yuav tsum tau ua rau txhua tus neeg mob ntawm tus kheej.

Noj ntau dhau

Kev mob ntshav khov (hypoglycemia) hnyav heev. Thaum muaj mob loj tsawv, tus mob yuav ua tau li qub los ntawm kev noj haus carbohydrates txaus. Hauv cov xwm txheej loj, thaum lub chaw tsis hnov qab tshwm sim, mob hlwb thiab qee cov mob hlwb, kev tawm tsam nres los ntawm kev qhia ntawm dextrose lossis glucagon tov.

Nrog kev noj tshuaj ntau dhau, ua rau qaug dab peg.
Nrog kev noj haus ntau dhau ntawm cov tshuaj, lub cev tsis xeev yuav tshwm sim.
Nrog kev noj tshuaj ntau dhau, qhov pib ntawm kev mob ntshav qab zib yog ua tau.
Nrog kev siv tshuaj ntau dhau ntawm cov tshuaj, mob puas siab ntsws hauv lub hlwb yog ua tau.

Kev cuam tshuam nrog lwm yam tshuaj

Thaum siv qee cov tshuaj, koj yuav tsum kho cov tshuaj ntawm cov tshuaj insulin, vim tias ntshav qabzib hauv cov ntshav tuaj yeem poob qis, uas ua rau kev txhim kho ntawm lub qog ntshav qab zib.

Cov tshuaj tiv thaiv hypoglycemic, salicylates, ACE inhibitors, tshuaj tua kab mob thiab qee cov sulfonamides txo cov nyhuv hypoglycemic ntawm cov kua dej no. Beta-blockers thiab lithium npaj tuaj yeem ob leeg txo qis thiab nce kev kho kom zoo ntawm kev noj tshuaj insulin.

Diuretics, salbutamol, adrenaline, glucagon, cov thyroid hormones, estrogens, qee qhov kev tiv thaiv qog, isoniazid, antipsychotics thiab prosthetic inhibitors thaum noj cov tshuaj no txo nws cov nyhuv hypoglycemic.

Cov kab mob zoo sib xws muaj cov tshuaj sib xws thiab kev kho mob:

Tujeo SoloStar cov lus qhia Koj yuav tsum paub txog insulin Lantus Ua li cas txhaj tshuaj insulin kom raug! Feem 1

Chaw tsim tshuaj paus Tujeo

Lub tuam txhab tsim khoom: Sanofi Aventis Deutschland GmbH, Lub Tebchaws Yelemees.

Kev tiv thaiv siab tshaj plaws tiv thaiv tshav ntuj ncaj qha. Tsis txhob cia kom khov, tab sis khaws cia rau hauv tub yees ntawm qhov kub ntawm tsis ntau tshaj + 8 ° C.

Kev Rov Tshawb Nrhiav Rau Tujeo

Feem ntau kev tshuaj xyuas ntawm tus kws kho mob thiab tus neeg mob yog qhov zoo.

Mikhailov AS, tus kws kho mob endocrinologist, Moscow: "Coob tus neeg tam sim no yws txog kev hloov mus rau cov tshuaj no. Insulin nws tus kheej yog qhov zoo, tab sis nws yog qhov tseem ceeb tshaj plaws los laij cov koob tshuaj. Qhov no, nws yuav zam zoo tsis muaj cov tsos mob tshwm sim."

Samoilova VV, tus kws kho mob endocrinologist, Nizhny Novgorod: "Niam pog tau mob ntshav qab zib tau ntau xyoo dhau los. Kuv, uas yog kws kho mob, nws tau xa nws los ntawm Lantus, uas peb tsis tau txais, rau Toujeo. Vim tias kuv tus kheej tau kawm txog qhov kev cuam tshuam ntawm cov insulin no. Qab zib tsis tuaj yeem "loj tuaj" rau nws yog tias qhov tshuaj ntau ntau yog.

Lawj xeeb

Karina, hnub nyoog 27 xyoo, Kiev: "Kuv nyiam nws tshaj qhov seem ntawm cov tshuaj insulin, vim tias nws muaj zog ntau dua, thiab koj tsuas yog yuav tsum tau txhaj nws ib hnub ib zaug. Nws yooj yim, siv tau thiab tsis cuam tshuam nrog kev ua si txhua hnub. Qab zib tseem nyob rau theem ntawm txhua lub sijhawm, tsis muaj. jumps, tshuaj xyuas tsis tu ncua. "

Victor, 36 xyoo, Voronezh: "Kuv tau noj cov tshuaj insulin no rau ib lub hlis. Ua ntej ntawd, muaj lwm yam tshuaj uas ua rau tsis muaj zog. Kuv tseem tsis nco qab txog khoom noj txom ncauj nrog nws."

Andrei hnub nyoog 44 xyoo, Moscow: "Kuv tau siv Lantus. Tam sim no lawv tsuas yog tsis sau nws tawm. Kuv yuav tsum txhaj tshuaj Toujeo, uas kuv tsis txaus siab rau. Ntawm Lantus, kev yoo suab thaj muaj txog 10, tam sim no 20-25."