Cov tshuaj insulin

Mob ntshav qab zib insulin-tiv thaiv mob mellitus yog ib tus kabmob uas paub tias yuav tsum muaj kev tswj kav insulin tas lub neej. Cov tshuaj insulin yog cov txhaj tshuaj.

Txog rau hnub tim, cov tuam txhab pharmacological ua ntau yam tshuaj insulin rau cov neeg mob ntshav qab zib, npaj rau kev txhaj tshuaj. Cov tshuaj sib txawv no tuaj yeem muaj npe sib txawv, zoo thiab tus nqi. Ib ntawm lawv yog cov tshuaj Humulin.

Cov Tshuaj Hauv Tshuaj

Cov tshuaj insulin yog qhov DNA tso tawm cov tshuaj tiv thaiv ntawm cov tshuaj hormones los ntawm tib neeg lub cev. Qhov sib txawv ntawm Humalog thiab insulin ntuj yog qhov sib txawv ntawm amino acid sib lawv liag ntawm txoj haujlwm 29 thiab 28 ntawm insulin B saw. Cov nyhuv tseem ceeb nws muaj yog kev tswj ntawm cov metabolism hauv qabzib

Humalog kuj muaj cov nyhuv anabolic. Hauv cov leeg nqaij, qhov ntau ntawm cov muaj roj fatty acids, glycogen thiab glycerol nce, cov khoom noj protein ntau nce, qib ntawm amino acid siv nce, tab sis kev siv ntau ntawm glycogenolysis, gluconeogenesis, thiab kev tso tawm ntawm cov amino acids txo.

Hauv lub cev ntawm cov neeg mob ntshav qab zib ntawm ob hom vim kev siv ntawm Humalog, qhov hnyav ntawm hyperglycemia uas tshwm tom qab noj mov tau txo kom ntau dua nrog kev hwm rau kev siv cov tshuaj lom neeg lub cev.

Rau cov neeg mob uas tau txais hom qis ntawm insulin ib txhij nrog rau lub sijhawm luv luv, koj yuav tsum xaiv qhov ntau npaum li cas ntawm ob hom tshuaj insulin kom ua tiav cov piam thaj hauv lub hnub.

Zoo ib yam li lwm cov tshuaj insulin, qhov ntev ntawm cov nyhuv ntawm cov tshuaj Humalog sib txawv hauv cov neeg mob sib txawv lossis txawv sijhawm nyob hauv ib tus neeg mob. Cov chaw muab tshuaj ntawm Humalog hauv cov me nyuam txuam nrog nws cov chaw muag tshuaj ntawm cov neeg laus.

Hauv cov neeg mob uas muaj ntshav qab zib hom 2 thiab noj ntau ntau ntawm sulfonylurea derivatives, kev siv ntawm Humalog ua rau muaj kev poob qis heev hauv qib glycated hemoglobin. Thaum Humalog siv ob hom ntshav qab zib, muaj qhov poob qis hauv lub qog ntshav qab zib tsawg thaum hmo ntuj.

Cov tshuaj tiv thaiv glucodynamic ua rau Humalog tsis cuam tshuam nrog qhov tsis muaj peev xwm ntawm hepatic thiab lub raum. Lub polarity ntawm cov tshuaj tau tsim rau tib neeg cov tshuaj insulin, txawm li cas los xij, cov nyhuv ntawm cov tshuaj tshwm sim sai dua thiab siv sijhawm tsawg dua.

Qhov tshwm sim ntawm Humalog yog qhov ua rau nws cov nyhuv pib sai (hauv li ntawm 15 feeb) vim muaj qhov nqus ntawm qhov tseem ceeb, uas ua rau nws muaj peev xwm los qhia nws ua ntej noj mov (hauv 1-15 feeb), thaum insulin zoo tib yam, uas muaj lub sijhawm luv luv, tuaj yeem ua haujlwm hauv 30 -45 feeb ua ntej noj mov.

Lub sijhawm ntawm cov nyhuv ntawm Humalog yog ntev dua li cov neeg sib xyaw rau ib txwm siv.

Cov Tshuaj Pharmacokinetics

Nrog kev txhaj tshuaj subcutaneous, qhov nqus ntawm lyspro insulin tshwm sim sai sai, nws Cmax tiav tom qab 1-2 teev. Vd ntawm cov kua dej nyob rau hauv kev sib xyaw ntawm cov tshuaj thiab cov tib neeg insulin zoo ib yam, lawv thaj tsam li ntawm 0.26 txog 0.36 litres ib kg.

Daim insulin-tiv thaiv ntshav qab zib: ib tus neeg tsis kam ua rau lwm yam tshuaj insulin, postprandial hyperglycemia, uas tsis tuaj yeem kho los ntawm lwm cov tshuaj insulin.

Daim ntawv uas tsis muaj tshuaj insulin-tiv thaiv cov ntshav qab zib: kev tawm tsam cov tshuaj tiv thaiv ntshav qab zib noj ntawm qhov ncauj (malabsorption ntawm lwm yam tshuaj insulin, postprandial hyperglycemia uas tsis tuaj yeem kho tau), kev phais mob thiab cuam tshuam ntawm cov ntshav qab zib (uas ua rau muaj kev mob ntshav qab zib).

Thov

Dosage Humalog yog txiav txim siab ib tus zuj zus. Humalog nyob rau hauv daim ntawv ntawm vials yog muab ob qho tib si subcutaneously thiab intravenously thiab intramuscularly. Lub humalogue nyob rau hauv daim ntawv ntawm cartridges tsuas yog subcutaneous.Kev txhaj tshuaj yog nqa tawm 1-15 feeb ua ntej noj mov.

Hauv nws daim ntawv dawb huv, cov tshuaj tau muab 4-6 zaug hauv ib hnub, ua ke nrog cov tshuaj insulin nrog cov nyhuv ntev, peb zaug ib hnub. Qhov luaj li cas ntawm ib koob tsis tuaj yeem dhau 40 units. Humalog hauv vials tuaj yeem sib xyaw nrog cov tshuaj insulin nrog cov nyhuv ntev dua hauv ib qho koob txhaj.

Lub pob txha taub hau tsis tsim rau tov Humalog nrog rau lwm yam tshuaj insulin npaj rau hauv nws thiab rau kev rov siv dua.

Qhov xav tau rau txo qis ntawm cov tshuaj insulin tuaj yeem tshwm sim thaum muaj kev cuam tshuam ntawm cov ntsiab lus ntawm carbohydrates hauv cov khoom noj, cov teeb meem lub cev tseem ceeb, ntxiv kev noj tshuaj uas muaj cov nyhuv hypoglycemic - sulfonamides, tsis xaiv cov beta-blockers.

Thaum noj clonidine, beta-blockers thiab reserpine, hypoglycemic cov tsos mob feem ntau tshwm sim.

Sab sij huam

Cov nyhuv tseem ceeb ntawm cov tshuaj no ua rau cov kev mob tshwm sim hauv qab no: nce tawm hws, pw tsis tsaug zog, tsis xeev plab. Tsis tshua muaj xwm txheej, kev ua xua thiab lipodystrophy tuaj yeem tshwm sim.

Txog tam sim no, tsis muaj qhov tsis zoo tshwm sim ntawm Humalog rau kev mob ntawm tus poj niam cev xeeb tub thiab tus mob embryo tau pom. Tsis muaj kev tshawb fawb cuam tshuam tau tshwm sim.

Tus pojniam uas muaj hnub nyoog yug menyuam uas muaj ntshav qab zib yuav tsum qhia tus kws kho mob txog qhov tau npaj lossis yuav xeeb menyuam. Rau cov neeg mob ntshav qab zib, lactation qee zaum yuav tsum tau yoog cov tshuaj insulin lossis kev noj haus.

Noj ntau dhau

Qhov tshwm sim: ib qho kev poob qis hauv cov ntshav qab zib, uas yog nrog los ntawm lub cev tsis muaj zog, tawm hws, mem tes ceev, mob taub hau, ntuav, tsis meej pem.

Kev Kho Mob: nyob rau hauv ib daim ntawv me me, hypoglycemia tuaj yeem nres los ntawm kev nqus ntawm cov piam thaj lossis lwm yam tshuaj los ntawm cov pab pawg qab zib, lossis cov khoom uas muaj suab thaj.

Kev mob ntshav qab zib tsawg mus rau ib tus neeg kawm ntawv qib siab yuav kho tau los ntawm kev txhaj tshuaj los ntawm cov kab mob ntshav qab zib thiab ntxiv cov piam thaj hauv lub cev tom qab cov neeg mob tus mob yuav nyob ruaj khov.

Cov neeg mob uas tsis teb rov qab rau glucagon yog muab cov tshuaj pleev ntsej muag rau ntshav qab zib. Cov teeb meem tsis nco qab, glucagon yog muab tshuaj subcutaneously lossis intramuscularly. Thaum tsis muaj cov glucagon lossis qhov tshuaj tiv thaiv rau kev txhaj tshuaj ntawm cov tshuaj no, cov tshuaj ua haujlwm ntawm cov kua nplaum ntawm lub cev yuav tsum tau ua.

Tam sim ntawd tom qab tus neeg mob rov qab nco qab, nws yuav tsum noj cov khoom noj uas muaj carbohydrates. Tej zaum koj yuav tsum noj zaub mov carbohydrates nyob rau yav tom ntej, thiab koj kuj yuav tsum tau saib xyuas tus neeg mob, vim tias nws muaj kev pheej hmoo ntawm kev rov qab los ntawm hypoglycemia.

Cov ntawv qhia tshuaj yuav tsum muab ceev cia ntawm qhov kub ntawm +2 txog +5 (hauv tub yees). Cia kom khov yog qhov tsis lees txais. Lub laub lossis lub taub ntim uas twb tau pib yuav tsis pub ntev tshaj 28 hnub ntawm chav tsev kub. Koj yuav tsum tiv thaiv Humalog los ntawm tshav ntuj ncaj qha.

Nws tsis tsim nyog siv cov tshuaj daws teeb meem thaum nws muaj qhov tsos huab, zoo li tuab lossis xim, thiab nyob ntawm qhov muaj cov khoom me me hauv nws.

Kev sib txuam ntawm Pharmacological

Cov nyhuv hauv lub ntsej muag hypoglycemic yog txo qis thaum noj qhov ncauj noj, tshuaj raws li cov thyroid hormones, beta2-adrenergic agonists, danazole, tricyclic antidepressants, thiazide-type diuretics, diazoxide, chlorprotixen, isoniazid, nicotinic acid, lithium carbonate, lithium carbonate.

Cov nyhuv hypoglycemic ntawm Humalog nce nrog beta-blockers, ethyl cawv thiab tshuaj uas muaj nws, fenfluramine, anabolic steroids, tetracyclines, guanethine, salicylates, tshuaj tiv thaiv hypoglycemic, sulfonamides, ACE inhibitors thiab MAO thiab octre.

Cov tshuaj yuav tsum tsis txhob sib xyaw nrog lwm cov khoom uas muaj cov tshuaj insulin ntawm cov tsiaj keeb kwm.

Siv tshuaj Humalog yuav siv tau (raug tshuaj saib xyuas mob) hauv kev sib xyaw nrog tib neeg cov tshuaj insulin, uas muaj cov nyhuv ntev dua, lossis siv nrog cov tshuaj hypoglycemic noj ntawm qhov ncauj, uas yog derivatives ntawm sulfonylurea.

LUS QHIA RAU KEV SIV KHUAJ KHO MOB KHO MOB

Lub Npe Tsis Muaj Npe International

Txhaj Tshuaj 100 IU / ml 3 ml

1 ml ntawm kev daws

cov tshuaj nquag - insulin lispro 100 IU / ml,

kev zam: metacresol, glycerin, zinc oxide, sodium hydrogen phosphate, hydrochloric acid 10% txhawm rau kho cov pH, sodium hydroxide 10% kev daws teeb meem kom kho cov pH, dej rau kev txhaj tshuaj.

Cov kua ntshiab tsis muaj kua

Tshuaj kho mob ntshav qab zib. Insulin thiab cov yeeb yam sai li sai tau.

Tsis siv neeg hloov xov tooj code A10AV04

Qhov pib ntawm lyspro insulin tom qab kev tswj hwm subcutaneous yog kwv yees li 15 feeb, qhov siab tshaj yog los ntawm 30 txog 70 feeb, lub sijhawm ua ntawm 2 mus rau 5 teev. Lub sijhawm ua haujlwm ntawm lyspro insulin tuaj yeem sib txawv raws li kev txhaj tshuaj, thaj chaw txhaj tshuaj, ntshav ntshav, ntsuas kub, kev ua haujlwm ntawm tus neeg mob, thiab lwm yam. Hauv cov ntshav, lyspro insulin khi rau alpha thiab beta globulins. Nquag, kev khi yog tsuas yog 5-25%, tab sis nws tuaj yeem nce ntxiv ntawm qhov muaj cov tshuaj tiv thaiv uas tshwm sim thaum txoj kev kho mob. Qhov ntim ntawm kev faib tawm ntawm cov tshuaj insulin lyspro zoo ib yam rau tib neeg thiab cov nyiaj yog 0.26 - 0.36 l / kg. Lyspro insulin metabolism tshwm sim hauv daim siab thiab lub raum. Hauv lub siab, thaum lub sijhawm kuaj ntshav ib zaug, nce txog 50% ntawm qhov rho tawm yog qhov tsis ciaj sia, hauv lub raum cov tshuaj hormones yog lim hauv cov glomeruli thiab rhuav tshem hauv cov tubules (txog 30% ntawm qhov tshuaj nqus). Tsawg dua li 1.5% ntawm lyspro insulin yog tawm hauv cov zis tsis hloov pauv. Ib nrab-lub neej yog nyob ntev li 1 teev.

Humalog® yog qhov sib piv ntawm tib neeg cov insulin thiab nws txawv ntawm nws tsuas yog rov qab ua ntu zus ntawm cov kab muag thiab lysine amino acid seem ntawm txoj haujlwm 28 thiab 29 ntawm cov kab insulin B. Lub luag haujlwm tseem ceeb ntawm Humalog® yog kev tswj ntawm cov metabolism hauv qabzib. Tsis tas li ntawd, txhua qhov insulins muaj qhov sib txawv anabolic thiab anti-catabolic rau ntau cov ntaub so ntswg ntawm lub cev. Hauv cov leeg nqaij thiab lwm cov nqaij (muaj qhov tsis suav ntawm lub hlwb), Humalog® tsim kev thauj mus ntev ntawm cov kua nplaum thiab amino acids, nrawm nrawm anabolic cov txheej txheem thiab inhibits protein catabolism. Hauv daim siab, Humalog® nce qabzib ntxiv thiab zom cov piam thaj hauv daim ntawv ntawm glycogen, inhibits gluconeogenesis thiab ua kom nrawm hloov pauv ntawm cov piam thaj ntau hauv cov rog. Glucodynamic teb rau Humalog® yog ywj siab ntawm daim siab thiab lub raum tsis ua haujlwm. Cov chaw muag tshuaj ntawm Humalog® hauv cov menyuam yaus zoo ib yam rau cov laus.

Kev ntsuas rau siv

mob ntshav qab zib mellitus rau cov neeg laus thiab cov menyuam hnub nyoog tshaj li 3 xyoos, hauv kev kho tshuaj insulin kom pom tias muaj cov piam thaj hauv tsev

stabilization ntshav qab zib nyob rau hauv thawj theem

Tsuas tshuaj thiab tswj hwm

Cov koob tshuaj ntawm Humalog® yog txiav txim los ntawm tus kws kho mob nyob ntawm tus neeg mob lub sijhawm. Qhov rhiab ntawm cov neeg mob rau cov exulinous insulin yog qhov sib txawv, 1 ntu ntawm subcutaneously siv cov tshuaj insulin txhawb qhov nqus ntawm 2 txog 5 g ntawm cov piam thaj. Humalog® pom zoo kom noj tshuaj kom tsis txhob ua ntej 15 feeb ua ntej noj mov lossis sai sai tom qab noj mov 4-6 zaug hauv ib hnub (kho mob monotherapy) lossis 3 zaug hauv ib hnub nyob rau hauv kev sib xyaw nrog cov insulin ntev dua. Cov tshuaj raug cai yuav tsum nyob ntawm chav tsev sov.

Cov qauv ntawm kev tswj hwm ntawm Humalog® hauv cov neeg laus thiab cov menyuam yaus yog tus kheej! Kev noj tshuaj ib leeg thiab txhua hnub tau muab kho tau raws li cov txiaj ntsig ntawm kev kawm ntxiv txog cov piam thaj hauv ntshav thiab zis thaum nruab hnub thiab nyob ntawm seb tus neeg mob xav tau metabolic npaum li cas.

Qhov xav tau txhua hnub ntawm Humalog® yuav txawv, feem ntau 0.5-1.0 IU / kg / hnub.

Kev tswj hwm ntawm Humalog® cov tshuaj tiv thaiv kab mob yog ua raws li kev txhaj tshuaj rau niaj zaus.Kev tswj hwm kev mob ntawm Humalog® tuaj yeem ua kom tswj tau ntshav qabzib thaum ketoacidosis, mob hnyav, lossis thaum phais thiab tom qab lub sijhawm txiav. Hauv qhov no, nws yog ib qho tsim nyog feem ntau los tswj cov qib ntawm cov piam thaj hauv cov ntshav. Cov txheej txheem rau kev lis ntshav nrog kev ntsuas ntawm 0.1 IU / ml thiab mus txog 1 IU / ml ntawm Humalog® hauv 0.9% sodium chloride tov lossis 5% dextrose nyob ruaj khov rau chav sov li 48 teev.

Rau subcutaneous Txoj kev lis ntshav ntawm Humaloga nrog lub twj tso kua mis, cov lus qhia rau lub twj tso kua mis yuav tsum ua raws nraim. Txoj kev lis ntshav lub cev yog hloov pauv txhua 48 teev. Yog tias hypoglycemia txhim kho, Txoj kev lis ntshav yog txuas mus ntxiv. Thaum siv lub twj tso kua mis, Humalog® yuav tsum tsis txhob sib xyaw nrog lwm cov insulins.

Txhaj tshuaj subcutaneous yuav tsum tau muab rau lub xub pwg, lub duav, lub pob tw lossis lub plab. Qhov chaw txhaj tshuaj yuav tsum tau hloov chaw kom tib qhov chaw siv tsis ntau tshaj li ib hlis ib zaug. Nrog kev tswj hwm hypodermic ntawm Humalog®, kev saib xyuas yuav tsum tau saib xyuas kom tiv thaiv ib txoj hlab ntsha ntawm qhov nkag mus txhaj tshuaj. Tom qab txhaj tshuaj, qhov chaw txhaj tshuaj yuav tsum tsis txhob zaws. Cov neeg mob yuav tsum tau txais kev qhia rau cov txheej txheem tseeb rau kev siv tshuaj insulin.

Humalog® cartridges tsis tas yuav rov ua haujlwm dua thiab tsuas yog siv tau yog tias lawv cov ntsiab lus yog cov kua ntshiab, tsis muaj kua, tsis muaj qhov pom pom.

Tsis txhob siv cov khoom lag luam yog tias nws muaj plaub ya ri. Cov qauv tsim ntawm lub lub laub txwv tsis pub lawv cov ntsiab lus sib xyaw nrog lwm cov tshuaj insulin amines ncaj qha rau hauv daim cartridge nws tus kheej. Cartridges tsis yog yuav tsum kom thim rov qab. Ua raws li cov khw muag cov lus qhia rau txhua tus neeg xaum xaum thaum tso daim ntawv rau hauv lub taub hau, txuas tus koob, thiab txhaj tshuaj insulin.

Xaiv qhov chaw txhaj tshuaj.

So cov tawv nqaij ntawm qhov chaw txhaj tshuaj nrog ib rab pas rwb pas nrig.

Tshem lub hau tiv thaiv sab nraud ntawm rab koob.

Kho cov tawv nqaij los ntawm rub nws los yog snapping nws mus rau qhov loj.

Ntxig rau rab koob thiab hno.

Tshem tawm rab koob thiab maj mam nias qhov chaw txhaj tshuaj rau ob peb feeb. Tsis txhob txhuam thaj chaw txhaj tshuaj.

Siv cov koob ntim rau sab nraud, tam sim ntawd tom qab qhia cov tshuaj, tshem tawm rab koob thiab nrhiav nws hauv qhov chaw zoo.

Nws yog ib qho tsim nyog yuav tsum tau hloov chaw txhaj tshuaj nyob rau hauv xws li qhov chaw ntawd tsis siv ntau tshaj ib hlis ib zaug.

Tsis txhob sib xyaw cov tshuaj insulin hauv vials nrog cov tshuaj insulin hauv daim cartridges.

Cov kev phiv tshuaj uas tshwm sim ntau dua li ib rooj plaub yog teev raws li kev paub hauv qab no: feem ntau (≥ 10%), feem ntau (≥ 1%, 0.1%, 0.01%, 0.1%, 0.01%) , Daim ntawv noj tshuaj: & nbsp daws rau cov dej num tswj thiab tswj txoj cai Txheej txheem:

1 ml muaj:

cov tshuaj heev : insulin lispro 100 ME,

zam txim : glycerol (glycerin) 16 mg, metacresol 3.15 mg, zinc oxide q .s. rau cov ntsiab lus ntawm Zn ++ 0.0197 mg, sodium hydrogen phosphate heptahydrate 1.88 mg, hydrochloric acid daws 10% thiab / lossis sodium hydroxide tov 10% q .s. mus rau pH 7.0-8.0, dej rau kev txhaj tshuaj q .s. txog li 1 ml.

Cov kua roj ntshiab thiab tsis muaj xim.

Pharmacotherapeutic pab pawg: tus neeg sawv cev hypoglycemic - luv-sawv kev insulin analog ATX: & nbsp

A.10.A.D.04 Tshuaj Ruam LizPro

Humalog® yog DNA tso ua ke ntawm cov tshuaj insulin. Nws txawv ntawm tib neeg cov insulin hauv kev rov qab hloov zuj zus ntawm cov amino acids ntawm txoj haujlwm 28 thiab 29 ntawm cov insulin B saw.

Kev ua tseem ceeb ntawm insulin lyspro yog kev cai ntawm cov metabolism hauv cov piam thaj. Ntxiv rau, nws muaj anabolic thiab anti-catabolic cuam tshuam rau ntau cov ntaub so ntswg lub cev. Hauv cov leeg nqaij, muaj qhov nce ntawm cov ntsiab lus ntawm glycogen, fatty acids, glycerol, kev nce ntawm synthesis protein thiab kev nce ntawm kev noj cov amino acids, tab sis tib lub sijhawm muaj glycogenolysis, gluconeogenesis, ketogenesis, lipolysis, protein catabolism thiab kev tso tawm ntawm cov amino acids.

Nws yog qhia tias nws yog equimolar rau tib neeg cov kua dej, tab sis nws cov kev ua tshwm sim ntau dua sai thiab kav rau lub sijhawm luv luv.

Lyspro insulin yog tus cwj pwm los ntawm qhov pib sai ntawm kev nqis tes ua (kwv yees li 15 feeb), vim nws muaj qhov nqus dej siab, thiab qhov no tso cai rau nws ua sai sai ua ntej noj mov (0-15 feeb ua ntej noj mov), tsis zoo li luv luv ua yeeb yam insulin (30-45 feeb) ua ntej noj mov). sai sai nws cov nyhuv thiab muaj lub sijhawm ua haujlwm luv (ntawm 2 txog 5 teev) piv nrog cov insulin neeg dog dig.

Hauv cov neeg mob uas muaj hom 1 thiab hom 2 mob ntshav qab zib mellitus, hyperglycemia uas tshwm sim tom qab kev noj mov tsawg dua nrog lyspro piv nrog soluble tib neeg cov kua dej. Rau cov neeg mob tau txais cov tshuaj insulin luv luv thiab hauv paus, nws yog ib qho tsim nyog yuav tsum xaiv cov koob tshuaj ntawm ob lub insulins kom thiaj li ua tiav qhov zoo tshaj plaws ntawm cov piam thaj hauv cov ntshav thoob plaws hnub.

Ib yam li txhua qhov kev npaj tshuaj insulin, lub sijhawm lyspro insulin ua haujlwm tuaj yeem sib txawv hauv cov neeg mob lossis sijhawm sib txawv ntawm tib tus neeg mob thiab nyob ntawm lub koob tshuaj, chaw txhaj tshuaj, ntshav ntshav, kub cev thiab kev tawm dag zog. Cov yam ntxwv ntawm lyspro insulin hauv cov menyuam yaus thiab cov hluas yog cov zoo sib xws ntawm cov neeg laus saib.

Hauv cov neeg mob uas muaj ntshav qab zib hom 2 tau txais cov tshuaj sulfonylurea ntau tshaj plaws, qhov ntxiv ntawm lyspro insulin ua rau txo qis glycosylated hemoglobin hauv pawg neeg mob no.

Lyspro insulin kho mob rau cov neeg mob uas muaj yam type 1 thiab ntshav qab zib hom 2 tau nrog ib tug neeg tsawg zuj zus lawm ntawm nocturnal hypoglycemia.

Glucodynamic lo lus teb tsis yog nyob ntawm kev ua haujlwm tsis zoo rau lub raum lossis nplooj siab.

Tom qab ua haujlwm subcutaneous, nws ceev nrawm thiab nce mus rau qhov siab tshaj plaws nyob rau hauv cov ntshav tom qab 30-70 feeb.

Qhov ntim ntawm kev faib tawm ntawm cov tshuaj insulin lispro zoo ib yam rau qhov ntim ntawm kev faib tawm ntawm tib neeg cov insulin thiab yog nyob rau thaj tsam ntawm 0.26-0.36 l / kg

Nrog kev tswj hwm subcutaneous, ib nrab-lub neej ntawm insulin lispro yog li 1 teev.

Hauv cov neeg mob uas lub raum thiab hepatic tsis txaus, tus nqi siab dua ntawm kev nqus ntawm lyspro insulin tseem piv rau cov neeg muaj peev xwm insulin.

Mob ntshav qab zib mellitus hauv cov neeg laus thiab menyuam yaus, xav tau kev kho tshuaj insulin kom muaj cov ntshav qabzib hauv cov ntshav.

Cov tshuaj tiv thaiv tsis haum rau lyspro insulin lossis lwm yam kev tshem tawm.

Cev xeeb tub thiab lactation:

Nyob rau lub sijhawm tam sim no, tsis muaj qhov tsis xav tau ntawm Lyspro insulin rau kev xeeb tub lossis rau kev noj qab haus huv ntawm tus menyuam / tus menyuam tshiab tau pom. Txog niaj hnub no, tseem tsis tau muaj kev tshawb fawb txog cov kabmob sib kis.

Thaum cev xeeb tub, qhov tseem ceeb yog tswj cov glycemic zoo hauv cov neeg mob ntshav qab zib uas tau txais kev kho mob nrog insulin. Qhov kev xav tau rau insulin feem ntau poob qis thaum thawj peb lub hlis thiab nce ntxiv thaum lub sijhawm thib ob thiab thib peb. Thaum lub sijhawm thiab yug tom qab yug, insulin yuav tsum poob ntau. Cov neeg mob ntshav qab zib yuav tsum sab laj nrog kws kho mob yog tias cev xeeb tub tshwm sim los yog npaj ua ntej. Kev cev xeeb tub hauv cov neeg mob ntshav qab zib, qhov tseem ceeb yog ua tib zoo saib xyuas cov piam thaj, nrog rau kev noj qab haus huv txhua yam.

Rau cov neeg mob ntshav qab zib thaum lub sijhawm pub niam mis, nws yuav tsum xaiv cov koob tshuaj insulin, khoom noj, lossis ob qho tib si.

Muab thiab kev coj:

Cov koob tshuaj ntawm Humalog® yog txiav txim los ntawm tus kws kho mob ntawm tus kheej, nyob ntawm seb cov concentration ntawm cov piam thaj hauv cov ntshav. Qhov tseeb ntawm kev muab tshuaj insulin yog tus kheej. Kev noj tshuaj Humalog® tuaj yeem muab ua ntej noj mov. Yog tias tsim nyog, Humalog® tuaj yeem muab rau noj sai tom qab noj mov. Qhov ntsuas kub ntawm cov tshuaj tso cai yuav tsum nyob ntawm chav sov.

Humalog® yuav tsum tau txhaj tshuaj raws li kev txhaj tshuaj subcutaneous lossis raws li kev ncua subcutaneous infusion siv lub twj tso kua mis. Yog tias tsim nyog (ketoacidosis, mob hnyav, lub sijhawm ntawm kev ua haujlwm lossis sijhawm hla sijhawm), Humalog® kev npaj kuj tseem tuaj yeem siv tshuaj pleev ib ce.

Subcutaneously yuav tsum txhaj rau hauv lub xub pwg, ncej puab, pob tw los sis plab. Qhov chaw txhaj tshuaj yuav tsum tau hloov chaw kom tib qhov chaw siv tsis ntau tshaj li 1 zaug hauv ib hlis.

Nrog kev tswj hwm subcutaneous ntawm Humalog® kev npaj, kev saib xyuas yuav tsum tau saib xyuas kom tsis txhob txais cov tshuaj rau hauv cov hlab ntshav. Tom qab txhaj tshuaj, qhov chaw txhaj tshuaj yuav tsum tsis txhob zaws. Tus neeg mob yuav tsum tau kawm siv cov txheej txheem kev txhaj tshuaj kom raug.

Cov lus qhia rau kev tswj hwm tshuaj yeeb tshuaj Humalog®

a) Npaj rau kev taw qhia

Kev daws ntawm Humalog yuav tsum meej thiab tsis muaj kob. Tsis txhob siv cov tshuaj Humalog® yog tias huab, huab, ua kom pom cov xim, cov xim tsis muaj zog, lossis cov khoom ua kom pom tau pom.

Thaum txhim kho lub taub ntim hauv cov koob txhaj tshuaj, txuas lub koob thiab txhaj tshuaj insulin, ua raws li cov chaw tsim khoom cov lus qhia uas suav nrog txhua tus xaum xaum xaum.

2. Xaiv qhov chaw txhaj tshuaj.

3. So ntawm daim tawv nqaij ntawm qhov chaw txhaj tshuaj.

4. Tshem tawm lub hau ntawm rab koob.

5. Kho cov tawv nqaij los ntawm rub nws lossis khaws nws rau hauv daim ntau quav. Ntxig lub koob txhaj tshuaj raws li cov lus qhia siv kev xaum xim.

6. Nias lub pob ntawd.

7. Tshem tawm rab koob thiab maj mam nyem qhov chaw txhaj tshuaj nrog paj rwb pas nrig rau ob peb feeb. Tsis txhob txhuam thaj chaw txhaj tshuaj.

8. Kev siv rab koob rab koob, khi lub koob thiab pov tseg.

9. Hloov chaw txhaj tshuaj kom lub chaw qub siv tsis ntau tshaj li ib zaug ib hlis.

Rau cov tshuaj Humalog® hauv mem hluav ceev ceev™

Ua ntej muab cov tshuaj insulin, koj yuav tsum nyeem QuickPen ™ Syringe cwj mem qhia siv.

c) Tso dej siab tswj hwm cov tshuaj insulin

Kev txhaj tshuaj tiv thaiv ntawm Humalog® kev npaj yuav tsum ua raws li kev siv tshuaj txhaj rau txoj kev txhaj tshuaj, piv txwv, txhaj tshuaj bolus tswj hwm lossis siv cov txheej txheem infusion. Hauv qhov no, feem ntau nws yog ib qho tsim nyog los tswj cov kev xav ntawm cov piam thaj hauv cov ntshav.

Txoj kev lis ntshav nrog kev siv zog los ntawm 0.1 IU / ml rau 1.0 IU / ml ntawm insulin lispro hauv 0.9% sodium chloride tov lossis 5% dextrose yog ruaj khov nyob rau hauv chav tsev rau 48 teev.

d) Subcutaneous insulin infusion siv lub twj tso kua mis

Rau Txoj kev lis ntshav ntawm Humalog®, Minimed thiab Disetronic twj yuav siv tau rau cov tshuaj insulin. Koj yuav tsum nruj me ntsis ua raws cov lus qhia uas tuaj nrog lub twj tso kua mis. Txoj kev lis ntshav lub cev yog hloov pauv txhua 48 teev. Thaum txuas lub system rau Txoj kev lis ntshav, saib xyuas txoj cai aseptic. Thaum muaj qhov qog ntawm hypoglycemic, Txoj kev lis ntshav yog nres kom txog rau thaum rov zoo. Yog tias muaj cov ntshav qabzib nyob hauv cov ntshav tsawg, tom qab ntawd koj yuav tsum qhia koj tus kws kho mob txog qhov no thiab txiav txim siab txo lossis txo qhov insulin infusion.

Lub twj tso kua mis tsis ua hauj lwm lossis kev txhaws hauv txoj kev lis ntshav dhau los tuaj yeem ua rau nce ntxiv hauv cov piam thaj. Yog tias lub sijhawm ua txhaum cai ntawm kev ua txhaum ntawm kev muab cov tshuaj insulin, koj yuav tsum ua raws li cov lus qhia thiab yog tias tsim nyog, qhia rau tus kws kho mob. Thaum siv lub twj tso kua mis, npaj Humalog should yuav tsum tsis txhob sib xyaw nrog lwm cov insulins.

Kev ntshav siab yog qhov ua tsis xav tau ntau tshaj nyob hauv kev kho mob insulin ntawm cov neeg mob ntshav qab zib. Kev mob ntshav khov ntau heev tuaj yeem ua rau tsis nco qab (hypoglycemic coma) thiab, tshwj tsis yog rau kev tuag.

Cov neeg mob yuav ntsib chaw ua xua nyob rau hauv daim ntawv ntawm daim tawv liab, o, lossis khaus ntawm qhov chaw txhaj tshuaj. Feem ntau, cov tsos mob no ploj mus li ntawm ob peb hnub lossis ob peb lim tiam. Feem ntau tsis tshua muaj tshwm sim kev tsis haum tshuaj dav dav nyob rau hauv qhov khaus yuav tshwm sim thoob plaws lub cev, urticaria, angioedema, kub taub hau, ua tsis taus pa, txo qis ntshav siab, tachycardia, nce hws. Cov teeb meem nyhav ntawm kev tsis haum suav nrog tuaj yeem ua rau tuag taus.

Qhov chaw txhaj tshuaj yuav loj tuaj lipodystrophy.

Cov xwm txheej ntawm txoj kev loj hlob tau pom. edema feem ntau nrog kev ceev nrawm ntawm cov ntshav qabzib concentration tiv thaiv keeb kwm yav dhau los ntawm kev siv tshuaj insulin ntxiv nrog kev pib tsis txaus siab glycemic tswj (saib Ntu "Cov Lus Qhia Tshwj Xeeb").

Overdose yog nrog kev txhim kho cov tsos mob ntawm tus mob hypoglycemia : qaug zog, tawm hws, tshaib plab, tshee hnyo, tachycardia, mob taub hau, kiv taub hau, plooj tsis pom kev, ntuav, tsis meej pem.

Me hypoglycemic lub sijhawm uas nws raug tso tseg los ntawm kev noj cov piam thaj lossis lwm yam piam thaj, lossis cov khoom muaj suab thaj (nws pom zoo kom ib txwm muaj tsawg kawg 20 g piam thaj nrog koj). Hais txog qhov hloov ntshav qab zib kom tsawg nws yuav tsum tau qhia rau tus kws kho mob uas koom nrog.

Kev kho Cov ntshav qog ntshav ntshav qis me ntsis tuaj yeem nqa tawm siv kev siv tshuaj intramuscular lossis subcutaneous ntawm glucagon, tom qab los ntawm kev noj haus ntawm cov carbohydrates tom qab ua kom ruaj ntseg ntawm tus neeg mob. Cov neeg mob uas tsis teb yog txhaj cov kua tshuaj dextrose (glucose) rau txoj leeg ntshav.

Yog tias tus neeg mob yog comatose , nws yuav tsum raug muab tshuaj intramuscularly lossis subcutaneously. Thaum tsis muaj glucagon los sis yog tias tsis muaj qhov tshuaj tiv thaiv rau nws qhov kev qhia, nws yog qhov tsim nyog los tswj txoj kev daws teeb meem kom tsis txhob quav tshuaj. Sai li sai tau tom qab rov qab - nco ntsoov, tus neeg mob yuav tsum tau muab cov zaub mov nplua nuj nyob hauv cov carbohydrates. Yuav tsum tau txais kev txhawb nqa kom ntau ntxiv ntawm carbohydrates thiab kev saib xyuas ntawm tus neeg mob tej zaum yuav tsum tau, txij li ib qho kev rov qab pib ntawm hypoglycemia yog ua tau.

Hais txog qhov hloov ntshav qab zib kom tsawg nws yuav tsum tau qhia rau tus kws kho mob uas koom nrog.

Qhov mob hnyav ntawm hypoglycemic kev txiav txim siab raug txo qis thaum sib koom tes nrog cov tshuaj hauv qab no : qhov ncauj tawm tsam, glucocorticosteroids, iodine-muaj cov thyroid hormones, beta 2 -adrenomimetics (e.g. ritodrin, terbutaline), tricyclic antidepressants, thiazide diuretics, diazoxide, phenothiazine derivatives.

Qhov mob hnyav ntawm hypoglycemic kev ua si ncethaum sib koom tes muab tshuaj nrog cov tshuaj hauv qab no : beta-blockers, thiab ethanol-muaj cov tshuaj, anabolic steroids, fenfluramine, guanethidine, tetracyclines, tshuaj tiv thaiv kab mob hypoglycemic, salicylates (piv txwv), tshuaj tua kab mob sulfonamide, qee cov tshuaj tiv thaiv kab mob (monoamine oxidase inhibitors), angiotensin inhibitors, angiotensin inhibitors, angiotensin inhibitors, angiotensin inhibitors, angiotensin inhibitors Cov. Humalog® yuav tsum tsis txhob muab coj los xyaw nrog tsiaj tshuaj insulin.

Thaum noj lwm yam tshuaj ua ke nrog Humalog®, koj yuav tsum sab laj nrog koj tus kws kho mob.

Yog tias koj xav siv lwm cov tshuaj, ntxiv rau cov tshuaj insulin, koj yuav tsum sab laj nrog koj tus kws kho mob (saib nqe lus "Cov lus qhia tshwj xeeb").

Hloov chaw ntawm tus neeg mob rau lwm hom lossis hom tshuaj insulin yuav tsum ua raws li kev saib xyuas mob nkeeg nruj me ntsis. Cov kev hloov hauv kev ua, hom (tus tsim khoom), hom (Tsis tu ncua, NPH, thiab lwm yam), hom (tsiaj, tib neeg, analog ntawm tib neeg insulin) thiab / lossis txoj kev tsim tawm (DNA recombinant insulin lossis insulin ntawm tsiaj keeb kwm) tuaj yeem ua rau qhov xav kom hloov cov koob tshuaj.

Cov kev mob uas cov cim qhia ntxov ntawm hypoglycemia tej zaum tsis tseem ceeb thiab tsis tshua hais tawm muaj xws li txuas ntxiv cov ntshav qab zib mellitus, kev kho mob insulin ntau ntxiv, kab mob hauv cov ntshav qab zib mellitus, lossis cov tshuaj xws li beta-blockers.

Hauv cov neeg mob hypoglycemic tshua tom qab hloov los ntawm tsiaj los ntawm cov tshuaj insulin rau tib neeg insulin, cov tsos mob thaum ntxov ntawm hypoglycemia yuav tsis tshua pom los yog txawv ntawm cov kev paub dhau los ntawm lawv cov insulin yav dhau los. Kev tswj tsis tau tus mob hypoglycemic lossis hyperglycemic tshua tuaj yeem ua rau tsis nco qab, tsis nco qab, lossis tuag. Kev noj tshuaj tsis txaus lossis tsis ncua kev kho mob, tshwj xeeb tshaj yog nyob rau cov neeg mob uas muaj ntshav qab zib hom ntshav qab zib mellitus, tuaj yeem ua rau tus mob hyperetcemia thiab ntshav qab zib ketoacidosis - cov mob uas yuav tsim kev phom sij rau tus neeg mob.

Txoj kev xav tau cov tshuaj insulin tuaj yeem txo qis dua thaum lub raum tsis ua haujlwm, nrog rau cov neeg mob hepatic tsis txaus ua rau muaj kev txo qis hauv cov txheej txheem ntawm gluconeogenesis thiab insulin metabolism. Txawm li cas los xij, nyob rau hauv cov neeg mob mob siab tsis ua haujlwm ntev, muaj peev xwm tiv thaiv insulin ntau dua tuaj yeem ua rau muaj kev nce ntxiv hauv insulin. Qhov xav tau ntawm cov tshuaj insulin tuaj yeem nce ntxiv thaum lub caij sib kis, nrog kev ntxhov siab los ntawm lub siab, nrog qhov nce ntawm cov carbohydrates hauv zaub mov.

Yog tias tus neeg mob tau ua kom lub cev muaj zog lossis ua kom noj zaub pauv ntau li qub yuav tau kho kom haum. Kev tawm dag zog tam sim ntawd tom qab noj mov tuaj yeem nce qhov kev pheej hmoo ntawm lub qog ntshav qab zib. Qhov tshwm sim ntawm lub pharmacodynamics ntawm kev sib piv ntawm kev ua kom sai ntawm tib neeg cov tshuaj insulin yog tias yog tias hypoglycemia txhim kho, tom qab ntawd nws tuaj yeem txhim kho tom qab kev txhaj tshuaj dua li thaum txhaj tshuaj tiv thaiv tib neeg lub cev.

Yog tias koj tus kws kho mob tau hais txog kev npaj tshuaj insulin nrog qhov sib xyaw ntawm 40 IU / ml hauv lub vial, koj yuav tsum tsis txhob sau cov tshuaj insulin los ntawm daim cartridge nrog cov tshuaj insulin ntawm 100 IU / ml siv cov koob txhaj tshuaj rau cov tshuaj insulin nrog rau 40 IU / ml.

Thaum siv cov tshuaj insulin nyob rau hauv kev sib xyaw nrog cov tshuaj ntawm thiazolidinedione pab pawg, qhov kev pheej hmoo ntawm kev txhim kho edema thiab mob plawv sai dua, tshwj xeeb tshaj yog nyob rau cov neeg mob uas muaj kab mob ntawm cov hlab plawv thiab muaj cov kev pheej hmoo ua rau mob plawv tsis ua haujlwm.

SIV LOS NTAWM KEV SIV LUB LIS HAIS LUS NOQuickPen ™

Humalog® QuickQen ™, Humalog® Sib tov 25 QuickPen Hum, Humalog® Mix 50 QuickPen ™

SYRINGE TES TAW QHIA RAU INSULIN

THOV NYEEM NYEEM cov lus qhia ua ntej siv

Cwj mem ceev ceev mem yog yooj yim siv. Nws yog cov cuab yeej siv los tswj cov tshuaj insulin (ib qho "insulin syringe mem") muaj 3 ml (300 units) ntawm kev npaj tshuaj insulin nrog ib qho dej ntawm 100 IU / ml. Koj tuaj yeem hno ntawm 1 txog 60 units ntawm insulin rau ib zaug txhaj. Koj tuaj yeem tsim koob tshuaj nrog qhov tseeb ntawm ib chav. Yog tias koj tau teeb tsa ntau cov koog. Koj tuaj yeem kho qhov koob tshuaj yam tsis poob los ntawm insulin.

Ua ntej siv QuickPen cwj mem kua muag, nyeem phau ntawv no kiag thiab ua raws nws cov lus qhia kom raug. Yog tias koj tsis ua raws li tag nrho cov lus qhia no, koj yuav tau txais cov tshuaj insulin tsawg dhau los yog siab dhau.

Koj QuickPen insulin cwj mem yuav tsum siv koj txoj kev txhaj tshuaj nkaus xwb. Tsis txhob kis tus cwj mem los yog rab koob rau lwm tus, vim qhov no yuav ua rau kis tus kab mob. Siv ib rab koob tshiab rau txhua txoj kev txhaj tshuaj.

TSIS TXHOB SIV cov xaum xaum hluav taws xob yog ib qho ntawm nws qhov chaw raug puas tsuaj lossis tawg. Yuav tsum tau xaum ib qho xaum xoob xoob uas siv thaum siv xaum xaum los yog nws puas ntsoog.

Cwj mem ceev ceev Kev npaj

Nyeem thiab ua raws cov lus qhia rau kev siv piav qhia hauv cov lus qhia rau kev siv tshuaj.

Kuaj daim ntawv lo rau ntawm lub phwj qhwv ua ntej txhua yam kev txhaj tshuaj kom paub tseeb tias hnub tas sij hawm ntawm cov tshuaj tsis tau tas sij hawm thiab koj siv hom insulin tseeb, tsis txhob tshem daim ntawv lo los ntawm tus cwj mem syringe.

Lus khaws xav : Cov xim ntawm cov xim khawm sai ntawm QuickPen syringe cwj mem sib phim xim ntawm cov xim ntawm daim phiaj xim ntawm daim duab thiab siv raws li hom tshuaj insulin.Hauv phau ntawv no, khawm koob tshuaj yog grayed tawm. Cov xim xiav ntawm QuickPen syringe mem lub cev qhia tau tias nws yog npaj rau siv nrog cov khoom lag luam Humalog.

Koj tus kws kho mob tau sau hom tshuaj insulin uas haum rau koj tshaj plaws. Ib qho kev pauv twg hauv kev kho tshuaj insulin yuav tsum tau ua yog nyob ntawm kev saib xyuas ntawm kws kho mob nkaus xwb.

Ua ntej siv cov koob txhaj syringe, nco ntsoov tias rab koob tau txuas nrog lub xias nqus.

Ua raws cov lus qhia tom qab no.

Cov lus nquag nug txog kev npaj QuickPen Syringe Cwj mem rau kev siv

-Kuv cov tshuaj insulin npaj yuav zoo li cas? Qee qhov insulin npaj yog turbid kev ncua, thaum lwm tus yog cov kev daws teeb meem meej, nco ntsoov nyeem cov lus piav qhia ntawm insulin hauv daim ntawv qhia kev txuas rau kev siv.

- Kuv yuav ua li cas yog tias kuv cov tshuaj noj kom siab dua 60 units? Yog tias qhov koob tshuaj uas tau muab rau koj yog siab dua 60 units, koj yuav tsum txhaj koob thib ob, lossis koj tuaj yeem tiv tauj koj tus kws kho mob txog qhov teebmeem no.

- Vim li cas kuv yuav tsum siv rab koob tshiab rau txhua txoj kev txhaj tshuaj? Yog tias cov koob tau rov qab siv dua, koj tuaj yeem tau txais cov koob tshuaj tsis yog lawm, koob yuav dhau los, lossis tus cwj mem yuav txhawm rau, lossis koj yuav kis tus kabmob vim muaj teeb meem tiv thaiv menyuam.

- Kuv yuav ua li cas yog tias kuv tsis paub meej tias muaj cov insulin ntau npaum li cas nyob hauv kuv lub thawv ntawv ? Muab cov tes rub kom lub taub ntawm rab koob taw thiaj poob. Cov nplai ntawm cov neeg lim hle hauv ntshiab qhia pom tias kwv yees li ntawm cov ntsuas ntawm insulin ntxiv. Cov zauv no TSIS TXHOB siv los teem lub koob tshuaj.

"Kuv yuav ua dab tsi yog tias kuv tsis tuaj yeem hle lub hau tawm ntawm rab koob txhaj tshuaj?" Txhawm rau kom tshem lub hau, rub rau nws. Yog tias koj muaj teeb meem hle lub hau, ua tib zoo tig lub hau moos thiab moos kom nws tso nws, ces rub nws kom hle lub hau.

Kuaj xyuas QuickPen Syringe Cwj mem rau Insulin

Kuaj koj cov insulin kom tsawg txhua zaus. Kev txheeb xyuas cov tshuaj insulin los ntawm cov xaum xaum yuav tsum tau ua ua ntej txhua qhov kev txhaj tshuaj ua ntej ib qho trickle ntawm insulin tshwm sim kom paub tseeb tias cov kua xaum xoos tau npaj rau cov koob tshuaj.

Yog tias koj tsis kuaj koj cov insulin kom tsawg ua ntej qhov trickle tshwm, koj yuav tau txais insulin ntau dhau los yog ntau dhau.

Cov Lus Nquag Nug Txog Kev Ntsuas Cov Insulin

- Vim li cas kuv thiaj yuav tsum kuaj xyuas kuv cov tshuaj insulin ua ntej txhua qhov txhaj tshuaj?

1. Qhov no nco ntsoov tias tus cwj mem tau npaj txhij rau koob tshuaj.

2. Qhov no ua pov thawj tias qhov ua kom yuam kev ntawm insulin los tawm ntawm rab koob thaum koj nias lub koob tshuaj.

3. Qhov no tshem tawm cov cua uas tuaj yeem sib sau hauv rab koob lossis insulin daim cartridge thaum siv.

- Kuv yuav ua li cas yog tias kuv tsis tuaj yeem nias lub pob koob tshuaj thaum lub sijhawm QuickPen's insulin kuaj?

1. Rhais ib rab koob tshiab.

2. Txheeb tshuaj insulin los ntawm tus cwj mem.

"Kuv yuav ua li cas yog tias kuv pom cov pa hauv lub thawv?"

Koj yuav tsum kuaj xyuas cov tshuaj insulin los ntawm tus cwj mem. Nco ntsoov tias koj tsis tuaj yeem khaws cov xaum xaum xaum nrog lub koob uas txuas rau nws, vim qhov no tuaj yeem ua rau kom muaj huab cua npuas hauv lub thawv ntim tshuaj insulin. Cov pa npuas me me tsis cuam tshuam rau qhov koob tshuaj, thiab koj tuaj yeem nkag rau koj cov tshuaj raws li ib txwm muaj.

Cov kev qhia ntawm koob tshuaj uas tsim nyog

Ua raws li kev cai ntawm asepsis thiab tshuaj tua kab mob uas koj tus kws kho mob pom zoo.

Nco ntsoov nkag mus rau qhov yuav tsum tau txhaj uas yog nias thiab tuav lub koob tshuaj thiab maj mam suav rau 5 ua ntej tshem rab koob. Yog tias cov tshuaj insulin tawm los ntawm rab koob, feem ntau koj tsis tau tuav rab koob nyob hauv qab koj daim tawv ntev.

Txo qhov ntxig ntawm qhov ntxig ntawm lub qhov ntswg yog qhov ib txwm. Qhov no yuav tsis cuam tshuam rau koj cov koob tshuaj.

Lub taub ntim koob txhaj tshuaj yuav tsis tso cai rau koj los kos ib lub koob tshuaj uas ntau tshaj ntawm cov lej ntawm insulin nyob hauv lub taub hau.

Yog tias hauv kev poob siab tias koj tau muab tshuaj tag nrho, tsis txhob muab rau lwm lub tshuaj. Hu rau koj tus sawv cev Lilly lossis mus ntsib kws kho mob kom tau kev pab.

Yog tias koj cov tshuaj ntau dua cov lej nyob hauv daim cartridge, koj tuaj yeem sau cov tshuaj insulin nyob hauv tus cwj mem no thiab tom qab ntawd siv tus cwj mem tshiab los ua kom tiav kev tswj hwm ntawm cov koob xav tau, LOSSIS nkag rau tag nrho cov koob tshuaj siv tus cwj mem tshiab.

Tsis txhob sim txhaj tshuaj insulin los ntawm kev hloov lub pob tshuaj. Koj yuav TSIS TAU tshuaj insulin yog tias koj tig lub pob tshuaj. Koj yuav tsum nias lub koob txhaj tshuaj rau hauv txoj kab ncaj ncaj kom tau txais koob tshuaj ntawm cov tshuaj insulin.

Tsis txhob sim hloov cov tshuaj ntawm cov tshuaj insulin thaum txhaj tshuaj.

Qhov siv koob yuav tsum tau muab pov tseg kom raws li cov kev pov tseg kho mob hauv zos.

Tshem tawm rab koob tom qab txhua hno tshuaj.

Koob Tshuaj Nug Txog

- Vim li cas nws thiaj li nyuaj nias lub khob tshuaj, thaum kuv sim tau txhaj?

1. Koj rab koob yuav txhaws tau. Sim txuas cov koob tshiab. Thaum koj ua qhov no, koj tuaj yeem pom li cas cov insulin tawm ntawm rab koob. Tom qab ntawv xyuas tus cwj mem rau cov tshuaj insulin.

2. Kev nias ceev ntawm lub koob tshuaj khawm tuaj yeem ua rau lub pob nyem. Kev qeeb qeeb nias lub koob txhaj tshuaj tuaj yeem ua rau nias yooj yim dua.

3. Kev siv lub taub loj dua yuav ua kom yooj yim nias lub pob koob txhaj thaum lub sijhawm txhaj.

Nrog koj tus kws kho mob tham txog seb rab koob xev twg thiaj zoo rau koj.

4. Yog tias nias lub pob thaum tswj hwm qhov koob tshuaj tseem nruj tom qab ua tiav tag nrho cov ntsiab lus saum toj saud, tom qab ntawv cov xaum xias yuav tsum tau hloov.

- Kuv yuav ua li cas yog tias tus cwj mem Quick syringe lo thaum siv?

Koj tus cwj mem yuav daig yog tias nws nyuaj rau kev txhaj tshuaj lossis teeb tshuaj. Txhawm rau tiv thaiv tus xaum xim los ntawm kev lo:

1. Rhais ib rab koob tshiab. Thaum koj ua qhov no, koj tuaj yeem pom li cas cov insulin tawm ntawm rab koob.

2. Tshawb xyuas cov tshuaj insulin.

3. Teem qhov tsim nyog yuav tau thiab txhaj tshuaj.

Tsis txhob sim ntub cov koob txhaj tshuaj, vim tias qhov no yuav ua kev puas tsuaj ntawm koob txhaj tshuaj.

Nias lub pob koob tshuaj yuav ua tau nruj yog tias muaj teeb meem txawv teb chaws (av, plua plav, zaub mov, insulin lossis lwm yam kua) nkag hauv qab tus cwj mem. Tsis txhob cia impurities nkag mus hauv cov xaum xim.

- Vim li cas cov tshuaj insulin ntws tawm ntawm rab koob tom qab kuv tau ua tiav kev noj tshuaj rau kuv?

Tej zaum koj yuav tau tshem rab koob sai dhau ntawm daim tawv.

1. Nco ntsoov tias koj pom tus naj npawb "0" hauv lub qhov rai qhov ntsuas qhov ntsuas.

2. Txhawm rau tswj hwm qhov koob tshuaj tom ntej, nias thiab tuav lub pob koob tshuaj thiab maj mam suav rau 5 ua ntej tshem rab koob.

- Kuv yuav ua dab tsi yog tias kuv cov koob tshuaj tau teeb tsa, thiab lub pob koob tshuaj dua tuaj txog sab hauv yog tias tsis muaj rab koob uas txuas nrog lub koob txhaj tshuaj?

1. Tig lub pob tshuaj rov qab rau xoom.

2. Txuas ib rab koob tshiab.

3. Ua ib qho tshuaj insulin.

4. Teem qhov koob tshuaj thiab hno.

- Kuv yuav ua dab tsi yog tias kuv teeb tshuaj tsis raug (ntau dua lossis dhau heev dhau)? Tig lub khob tshuaj rov qab lossis txuas ntxiv kom kho qhov koob tshuaj.

- Kuv yuav ua li cas yog tias kuv pom cov insulin tawm hauv lub tes tsho hauv lub tes tsho thaum xaiv los yog hloov kho dua? Tsis txhob noj ib qho tshuaj, zoo li koj yuav tsis tau txais koj cov tshuaj tag nrho. Teeb tus xaum xaum rau tus naj npawb xoom thiab rov tshawb xyuas cov tshuaj insulin los ntawm cov xaum xaum (saib ntu "Tshawb xyuas QuickPen syringe cwj mem rau Insulin Xa"). Teem qhov tsim nyog yuav tau thiab txhaj tshuaj.

- Kuv yuav ua li cas yog hais tias tsim tsis tau kuv cov tshuaj tag nrho? Tus xaum xaum yuav tsis tso cai rau koj los tsim cov koob tshuaj ntau dhau ntawm cov lej ntawm cov insulin nyob hauv daim ntim taub hau. Piv txwv li, yog tias koj xav tau 31 units, thiab tsuas yog 25 units nyob hauv daim cartridge, tom qab ntawd koj yuav tsis tuaj yeem hla tus lej 25 thaum lub sijhawm nruab. Tsis txhob sim teeb tsa qhov koob los ntawm kev mus ntawm tus lej no. Yog tias cov koob tshuaj ib nrab tawm hauv tus cwj mem, ces koj tuaj yeem:

1. Nkag mus rau ib nrab ntawm cov koob tshuaj no, thiab tom qab ntawd nkag mus rau qhov seem uas yog siv tus cwj mem tshiab, lossis

2. Tshaj tawm cov tshuaj tag nrho los ntawm cov kua mem tshiab.

- Vim li cas kuv tsis tuaj yeem tsim koob tshuaj kom siv cov tshuaj insulin uas tsawg nyob hauv kuv lub taub hau? Lub koob txhaj tshuaj yog tsim los tso cai rau kev tswj hwm ntawm tsawg kawg 300 units ntawm insulin. Lub cuab yeej ntawm rab koob xaum hluav taws xob tiv thaiv lub pob txha taub los ntawm kev ua kom tiav, vim tias qhov tshuaj me me uas tseem nyob hauv daim cartridge tsis tuaj yeem raug txhaj nrog qhov tseeb uas tsim nyog.

Cia thiab pov tseg

Rab koob txhaj tshuaj tsis tuaj yeem siv yog tias nws tau nyob sab nraum lub tub yees rau ntau tshaj li lub sijhawm teev nyob hauv Cov Lus Qhia rau Siv.

Tsis txhob muab xaum xaum hluav taws xob nrog rab koob txuas rau nws. Yog tias rab koob raug tso rau hauv qhov txuas, cov insulin tuaj yeem tawm ntawm tus cwj mem, lossis insulin yuav qhuav hauv rab koob, ua rau rab koob txhaws, lossis cua npuas tuaj yeem tsim nyob rau hauv lub taub hau.

Cov koob txhaj tshuaj uas siv uas tsis siv yuav tsum muab tso rau hauv tub yees rau ntawm qhov kub li 2 ° C txog 8 ° C. Tsis txhob siv cov xwj xem hluav taws xob yog tias nws tau khov.

Daim ntaub qhwv uas koj siv tam sim no yuav tsum khaws cia rau qhov kub tshaj li 30 ° C thiab hauv qhov chaw tiv thaiv los ntawm kub thiab lub teeb.

Xa mus rau cov lus qhia rau kev siv rau kev paub tiav nrog kev khaws cia cov qauv ntawm cov xaum xaum.

Khaws cov xaum xaum kom deb ntawm qhov chaw ncav cuag ntawm cov menyuam.

Muab cov koob txhaj tshuaj siv rau hauv cov ntaub ntawv pov thawj-pov thawj, cov thoob ntim rov qab (piv txwv, cov khoom ntim rau cov khoom siv tshuaj lom neeg lossis khib nyiab), lossis raws li kev pom zoo los ntawm koj tus kws kho mob.

Cuam tshuam ntawm cov phwj uas siv tsis muaj koob uas txuas nrog lawv thiab ua raws li cov lus pom zoo ntawm koj tus kws kho mob.

Tsis txhob ntim cov thawv ntim ntim rau hauv cov ntse ntim.

Nug koj tus kws kho mob seb yuav ua li cas thiaj li muaj cov thoob ntim hauv cov thoob koj thaj tsam.

Humalog®, Humalog® nyob rau hauv QuickPen-syringe cwj mem, Humalog® sib xyaw 50 hauv QuickPen-syringe cwj mem, Humalog® sib xyaw 25 hauv QuickPen ring koob txhaj tshuaj yog cov cim lag luam ntawm Eli Lilly thiab Tuam Txhab.

Lub QuickPen ™ Syringe cwj mem tau raws li qhov tseeb kev noj tshuaj thiab kev ua haujlwm ntawm ISO 11608 1: 2000

Nco ntsoov tias koj muaj cov yam hauv qab no:

Pen Cwj mem ceev ceev

Tshiab rab koob rau cov hlaws tes

Swab ntub dej nrog cawv

QuickPen Koob txhaj tshuaj thiab Cheebtsam Koob * (* Muag Cais), Caj mem phis tog - saib pic 3 .

Xim Coding ntawm Koob Yees Duab - saib pic 2 .

Kev siv tus cwj mem ib txwm siv

Ua raws li cov lus qhia no kom ua tiav txhua kev txhaj tshuaj.

1. Npaj ceev mem hluav taws xob

Rub lub hau tawm ntawm rab tes xaum qhwv kom tshem nws. Tsis txhob kiv taub hau. Tsis txhob rub daim ntawv lo los ntawm cov xaum xim.

Nco ntsoov xyuas koj cov insulin rau:

Hnub tas sij hawm

Saib xyuas: Nco ntsoov nyeem daim ntawv xaj txhua lub sijhawm kom paub tseeb tias koj siv hom tshuaj insulin.

Rau kev ua yeeb yam rau insulin nkaus xwb:

Maj mam muab cov koob txhaj tshuaj npuag 10 npaug ntawm koj xib teg

tig lub cwj mem dhau 10 zaug.

Kev sib xyaw xim tseem ceeb heev txhawm rau kom ntseeg tseeb tias tau txais qhov tshuaj yog. Cov tshuaj insulin yuav tsum saib zoo kom sib xyaw.

Nqaj koob tshiab.

Tshem daim ntawv nplaum tawm ntawm lub hau ntawm rab koob.

Siv cov paj rwb ntub dej nrog cawv kom so lub roj hmab disc kawg ntawm lub thawv ntim.

Muab rab koob tso rau hauv lub hau txoj cai ntawm txoj kab ntawm kev txhaj tshuaj tus cwj mem.

Ntsia ntawm tus kab kom txog thaum siab txuas.

2. Txheeb xyuas QuickPen Syringe Cwj mem rau Insulin

Ceev faj: Yog tias koj tsis kuaj koj cov insulin tsawg ua ntej txhaj txhua, koj tuaj yeem txais cov tshuaj insulin qis dhau los yog qis dhau.

Tshem lub hau hau sab nraud. Tsis txhob muab pov tseg.

Tshem lub hau ntawm lub hau thiab muab pov tseg.

Teeb 2 chav nyob los ntawm kev hloov cov koob tshuaj khawm.

Taw tes cwj mem.

Coj mus rhaub rau ntawm lub laub cartridge kom tso pa tawm rau hauv

Nrog rab koob taw qhov taw, nias lub khawm koob tshuaj kom txog thaum nws nres thiab tus lej "0" tshwm nyob rau hauv lub ntsuas qhov ntsuas.

Tuav lub khawm koob tshuaj nyob rau hauv txoj haujlwm recessed thiab suav maj mam mus txog 5.

Kev kuaj xyuas cov tshuaj insulin yog ua tiav thaum ua tiav cov tshuaj insulin thaum kawg ntawm rab koob.

Yog tias qhov ua kom yuam kev ntawm insulin tsis tshwm sim thaum kawg ntawm rab koob, tom qab ntawv rov qab ua cov kauj ruam ntawm tshuaj insulin kom tsawg plaub zaug, pib txij li ntu 2B thiab xaus nrog point 2G.

Nco tseg: Yog tias koj tsis pom kev tawm ntawm insulin tshwm sim los ntawm rab koob, thiab teeb tsa cov koob tshuaj yuav nyuaj, tom qab ntawd hloov lub koob thiab rov ua qhov ntsuas xyuas qhov insulin kom tsawg los ntawm cov xaum xaum.

Tig lub pob tshuaj rau qhov ntau qhov koj xav tau kev txhaj tshuaj.

Yog tias koj tau poob ntau chav nyob, koj tuaj yeem kho qhov koob tshuaj los ntawm kev hloov cov koob tshuaj khawm rau qhov tsis sib xws.

Siv rab koob tso rau hauv qab ntawm daim tawv nqaij uas siv cov txheej txheem txhaj tshuaj uas koj tus kws kho mob pom zoo.

Muab koj tus ntiv tes xoo tso rau ntawm lub koob tshuaj khawm thiab khov kho nias lub koob tshuaj kom txog thaum nws nres kiag li.

Txhawm rau nkag mus rau tag nrho cov tshuaj, tuav lub koob tshuaj thiab maj mam suav rau 5.

Tshem rab koob tawm hauv qab daim tawv nqaij.

Lus khaws xav : Txheeb xyuas thiab xyuas kom tseeb tias koj pom tus lej "0" hauv lub qhov ntsuas qhov ntsuas tshuaj, kom paub meej tias koj tau nkag mus rau tag nrho cov tshuaj.

Ua tib zoo muab lub hau ntim rau ntawm rab koob.

Nco tseg: Tshem tawm rab koob tom qab txhua qhov kev txhaj tshuaj tiv thaiv kom tsis txhob muaj cua npuas los nkag rau hauv lub taub hau.

Tsis txhob muab xaum xaum hluav taws xob nrog rab koob txuas rau nws.

Tshem tawm rab koob nrog lub hau sab nraud ntawm nws thiab pov tseg nws raws li cov lus qhia ntawm koj tus kws kho mob.

Muab lub hau tso rau ntawm tus cwj mem syringe, sib txuas lub hau txiav nrog lub koob taw qhia los ntawm kev thawb lub hau ntawm txoj kab ncaj nraim rau ntawm tus cwj mem syringe.

Nthuav qhia 15 units (saib pic 4) 4) .

Txawm hais tias cov lej raug luam tawm nyob rau hauv lub qhov ntsuas qhov ntsuas tshuaj yog cov lej, tus lej tsis raug luam tawm raws li txoj kab ncaj nruab nrab ntawm cov lej.

Nco tseg: Lub tes tsho syringe yuav tsis tso cai rau koj los teev tus lej ntawm qhov muaj ntau tshaj li qhov muaj pes tsawg nyob rau hauv xaum xaum.

Yog tias koj tsis paub tseeb tias koj tau txhaj tshuaj tag nrho, tsis txhob noj tshuaj ntxiv.

Cawv rau lub peev xwm tsav transp. Wed thiab pluab.:

Tus neeg mob lub peev xwm mloog tau zoo thiab qhov tshuaj tiv thaiv tus kab mob yuav tuaj yeem ua rau mob ntshav qab zib los yog hyperglycemia cuam tshuam nrog kev noj tshuaj tsis zoo. Qhov no tuaj yeem ua rau muaj kev pheej hmoo hauv cov xwm txheej uas cov peev xwm no muaj qhov tseem ceeb tshwj xeeb (piv txwv li tsav tsheb lossis kev siv tshuab ua haujlwm).

Cov neeg mob yuav tsum tau ceev faj kom tsis txhob mob hypoglycemia thaum tsav tsheb. Qhov no tseem ceeb tshwj xeeb tshaj yog rau cov neeg mob uas muaj qhov txo qis lossis tsis hnov ​​qab los ntawm kev twv ua ntej ntawm tus mob hypoglycemia lossis hauv tus neeg uas muaj ntshav tsis txaus feem ntau pom. Hauv cov xwm txheej no, nws yog qhov yuav tsum tau soj ntsuam qhov tsim nyog ntawm kev tsav tsheb.

Tso tawm daim ntawv / muab ntau: Cov tshuaj rau cov txheej txheem rau kev tso dej thiab tshuaj hauv qab, 100 IU / ml. Cov:

3 ml ntawm cov tshuaj rau ib lub cartridge. Tsib cartridges ib lub hlwv. Ib qho hlwv ua ke nrog cov lus qhia rau kev siv rau hauv thawv ntawv thawv.

3 ml ntawm cov tshuaj hauv daim cartridge sib xyaw rau hauv QuickPen ™ koob txhaj tshuaj.Tsib QuickPen ™ syringe cwjmem txhua, nrog rau cov lus qhia rau kev siv thiab QuickPEN ™ Syringe cwj mem cov lus qhia siv rau hauv cov thawv thawv ntawv.

Khaws rau hauv tub yees ntawm qhov kub ntawm 2-8 ° C.

Siv yeeb tshuaj hauv ib lub thawv ntawv sau / cov xaum xaum yuav tsum muab cia rau hauv chav tsev kub tsis tshaj 30 ° C, tsis pub dhau 28 hnub.

Tiv thaiv los ntawm tshav ntuj ncaj qha thiab kub. Tsis txhob pub kom khov.

Khaws tsis ncav cuag ntawm cov menyuam yaus. 10/27/2015 Lus qhia txheej txheem

Cov lus qhia rau kev siv:

Qhov tshuaj Humalog yog ib qho kev kho mob ntshav qab zib.

Cov chaw muag tshuaj

Humalog yog cov hluavtaws sib piv ntawm cov neeg ua haujlwm luv insulin. Nws tswj hwm tus metabolism hauv cov piam thaj hauv lub cev, txo nws cov qib hauv cov ntshav. Hauv qhov no, dhau li ntawm cov piam thaj hauv daim ntawv ntawm glycogen accumulates hauv cov leeg thiab nplooj siab. Insulin Humalog ua kom nrawm ntawm cov synthesis protein, kev noj cov amino acids, maj mam zom cov glycogen rau qabzib, thiab ua rau qeeb ntawm kev tsim cov piam thaj los ntawm cov rog thiab cov protein.

Kev siv tshuaj insulin luv luv feem ntau yog sib xyaw nrog basal kom zoo dua tswj ntshav qabzib. Lub sijhawm ntawm cov ua ntawm Humalog sib txawv ntawm cov neeg mob sib txawv thiab nyob ntawm ntau yam.

Xws li hom 2 mob ntshav qab zib mellitus, thaum tus neeg mob tau txais ib txhij hypoglycemic tus neeg sawv cev hauv cov ntsiav tshuaj thiab cov insulin no, cov ntshav qab zib tswj yog ntau txhim khu kev qha. Qhov no yog xav txog qhov txo qis ntawm glycated hemoglobin qhov tseem ceeb thaum tshuaj xyuas kev kho mob. Humalog txo qis ntau zaus ntawm kev txo cov ntshav qab zib thaum hmo ntuj. Qhov mob ntawm daim siab thiab ob lub raum ntawm tus neeg mob tsis cuam tshuam rau cov metabolism hauv cov tshuaj.

Raws li cov lus qhia, Humalog tau nrawm thiab pib ua 15 feeb tom qab kev tswj hwm, yog li nws tuaj yeem siv 15 feeb ua ntej noj mov, tsis zoo li lwm cov yeeb yam luv luv, uas siv 30 mus rau 45 feeb. Lub sijhawm nws lub sijhawm luv dua li cov neeg siv tshuaj insulin, thiab tsuas yog 2 - 5 teev xwb.

Cov lus qhia rau kev siv Humalog

Cov tshuaj yog muab tshuaj subcutaneously los ntawm kev txhaj tshuaj lossis lub tshuaj insulin tam sim ntawd ua ntej noj mov. Qhov chaw txhaj tshuaj yog lub xub pwg, ncej puab, plab lossis pob tw. Koj yuav tsum tau hloov rau lawv thiaj li nyob rau hauv ib qho chaw txhaj tshuaj tsis tas yuav ua dua ob zaug hauv 1 hlis, qhov no yuav tiv thaiv kom tsis txhob ua cov nqaij mos. Peb yuav tsum sim kom tsis txhob nkag rau hauv cov hlab ntshav. Tsis txhob txhuam qhov chaw txhaj tshuaj tom qab txhaj tshuaj kom nqus tau zoo dua ntawm cov tshuaj.

Thaum mob ceev, Humalog insulin tuaj yeem muab tshuaj rau hauv cov kev kho mob physiological (phais, ketoacidosis, thiab lwm yam). Ua ntej txhaj tshuaj, nco ntsoov tias cov tshuaj tov yog sov rau chav sov.

Cov koob tshuaj ntawm Humalog yog tus kheej rau txhua tus neeg mob thiab suav los ntawm tus kws kho mob. Tsis txhob sib xyaw ua ke ntawm cov tshuaj insulins.

Qhov tshuaj tiv thaiv Humalog tsawg dua thaum noj nrog glucocorticoids, tshuaj tiv thaiv qhov ncauj, tshuaj tua cov thyroid, thiab nicotinic acid. Ethanol, salicylates, ACE inhibitors, beta-blockers nce cov nyhuv ntawm cov tshuaj insulin.

Thaum cev xeeb tub thiab lactation, kev tswj hwm ntawm cov tshuaj insulin no siv tau, tab sis kev saib xyuas ntau ntxiv ntawm cov ntshav qab zib yuav tsum muaj. Thaum lub sij hawm pub mis niam, ib qho rov qab siv lub koob tshuaj ntau zaus vim tias xav tau cov tshuaj insulin ntau dua. Cov tshuaj muaj cai siv rau hauv menyuam yaus.

Sab sij huam

Qee lub sij hawm nrog kev noj ntau dhau los yog cov yam ntxwv ntawm lub cev qhov kev tawm tsam, Humalog tuaj yeem ua rau cov ntshav qabzib tsawg zuj zus - hypoglycemia.

Qee zaum, muaj kev fab tshuaj rau cov tshuaj hauv daim ntawv ua pob, ua pob liab liab, khaus ntawm daim tawv nqaij, yog mob hnyav - mob caj dab.

Ntawm qhov chaw txhaj tshuaj, txo cov roj subcutaneous txheej txheej, lipodystrophy, tuaj yeem sau tseg.

Dosage daim ntawv

Kev daws rau iv thiab sc coj

tshuaj insulin lispro 100 IU

Cov zam: glycerol (glycerin) - 16 mg, metacresol - 3.15 mg, zinc oxide (q.s.rau cov ntsiab lus ntawm Zn2 + 0.0197 μg), sodium hydrogen phosphate heptahydrate - 1.88 mg, hydrochloric acid tov 10% thiab / lossis sodium hydroxide tov 10% - q.s. mus txog pH 7.0-8.0, dej d / i - q.s. txog li 1 ml.

Tej yam kev mob tshwj xeeb

Hloov chaw ntawm tus neeg mob mus rau lwm hom lossis hom tshuaj insulin yuav tsum tau ua raws li kev saib xyuas mob nkeeg nruj me ntsis. Cov kev hloov hauv kev ua, hom (tsim tawm), hom (piv txwv, tsis tu ncua, NPH, Daim kab xev), hom (tsiaj, tib neeg, tib neeg insulin analogue) thiab / lossis cov qauv kev tsim tawm (DNA recombinant insulin lossis insulin ntawm keeb kwm tsiaj) yuav xav tau hloov pauv cov koob tshuaj.

Kev mob uas cov cim qhia ntxov ntawm hypoglycemia yog qhov tsis tseem ceeb thiab tsis tshua hais tawm muaj xws li txuas ntxiv cov ntshav qab zib mellitus, kev kho mob insulin ntau ntxiv, kab mob hauv cov kab mob ntshav qab zib mellitus, lossis tshuaj noj, xws li beta-blockers.

Hauv cov neeg mob hypoglycemic tshua tom qab hloov los ntawm tsiaj los ntawm cov tshuaj insulin rau tib neeg insulin, cov tsos mob thaum ntxov ntawm hypoglycemia yuav tsis tshua pom los yog txawv ntawm cov kev paub dhau los ntawm lawv cov insulin yav dhau los. Kev tswj tsis tau tus mob hypoglycemic lossis hyperglycemic tshua tuaj yeem ua rau tsis nco qab, tsis nco qab, lossis tuag.

Kev noj tshuaj tsis txaus lossis tsis ua haujlwm ntawm kev kho mob, tshwj xeeb tshaj yog muaj cov kab mob ntshav qab zib insulin-tuaj yeem ua rau hyperglycemia thiab ntshav qab zib ketoacidosis, cov xwm txheej uas yuav tsim kev phom sij rau tus neeg mob.

Txoj kev xav tau cov tshuaj insulin tuaj yeem txo cov neeg mob lub raum tsis ua haujlwm, zoo ib yam li cov neeg mob lub siab ua haujlwm vim qhov ua haujlwm tsawg kawg ntawm gluconeogenesis thiab insulin metabolism. Txawm li cas los xij, nyob rau hauv cov neeg mob mob siab tsis ua haujlwm ntev, muaj peev xwm tiv thaiv insulin ntau dua tuaj yeem ua rau muaj kev nce ntxiv hauv insulin.

Qhov xav tau ntawm cov tshuaj insulin tuaj yeem nce nrog cov kis kab mob, kev ntxhov siab hauv lub siab, nrog qhov nce ntawm cov carbohydrates hauv cov zaub mov noj.

Yog hais tias tus neeg mob lub cev qoj ib ce ntau zog los yog pauv noj zaub mov zoo ces kuj tseem yuav tsum tau txhaj koob tshuaj. Kev tawm dag zog tam sim ntawd tom qab noj mov tas yuav ua rau muaj ntshav qab zib tsawg dua. Ib qhov tshwm sim ntawm lub pharmacodynamics ntawm kev ua yeeb yam sai sai ntawm insulin analogues yog tias yog tias cov ntshav qog ntshav qab zib, tom qab ntawd nws tuaj yeem txhim kho tom qab txhaj tshuaj dua li thaum txhaj cov tshuaj tiv thaiv tib neeg cov tshuaj insulin.

Tus neeg mob yuav tsum tau ceeb toom tias yog tias tus kws kho mob tau sau ib qho tshuaj insulin nrog rau 40 IU / ml hauv lub vial, ces cov tshuaj insulin yuav tsum tsis txhob los ntawm daim cartridge nrog cov tshuaj insulin ntawm 100 IU / ml nrog koob txhaj rau kev txhaj tshuaj insulin nrog qhov sib luag ntawm 40 IU / ml.

Yog tias tsim nyog, noj lwm cov tshuaj thooj txhij nrog cov tshuaj

Mob ntshav qab zib mellitus hauv cov neeg laus thiab cov menyuam yaus, xav tau kev kho tshuaj insulin kom muaj cov suab thaj hauv lub cev.

Cov Yuav Tsum Muaj

Hypersensitivity rau lub Cheebtsam ntawm cov tshuaj.

Tus nqi hluav taws xob hauv lwm lub nroog

Yuav Cov Ntawv Humalog, Humalog hauv St. Petersburg, Humalog hauv Novosibirsk,

Ultrashort insulin Humalog: kawm txhua yam koj xav tau. Hauv qab no koj yuav pom cov lus qhia rau kev siv sau ua lus yooj yim. Nyeem cov lus teb rau cov lus nug:

Ultrashort Insulin Humalog: Cov Lus Qhia Ntxiv

Tus xaib xaib tsis pom zoo kom yuav cov tshuaj insulin thiab ntshav qab zib los ntawm txhais tes, raws li kev tshaj tawm. Kev yuav los ntawm cov tib neeg, koj muaj feem ntau yuav tau txais qhov tsis muaj txiaj ntsig, tsis muaj yeeb tshuaj. Thaum piam, feem ntau seem tseem pob tshab. Los ntawm cov tsos ntawm insulin nws tsis yooj yim sua kom txiav txim siab nws zoo. Yog li, koj yuav tsum tau yuav nws nkaus xwb hauv lub khw muag tshuaj muaj suab npe nrov, uas ua raws li cov cai ntim khoom.

Tso tawm daim ntawv thiab muaj pes tsawg leeg

Insulin Humalog yog muaj raws li cov xim tsis muaj xim rau kev txhaj tshuaj. Siv rau subcutaneous thiab leeg tswj hwm. Lub hauv paus ua haujlwm tseem ceeb ntawm cov tshuaj yog Lizpro insulin, qhov sib txawv ntawm qhov uas yog qhov hloov pauv ntawm cov amino acid sib txuas hauv cov kab hauv insulin B.

Cov tshuaj raug muag hauv 3 ml cartridges. Rau kev yooj yim ntawm kev tswj hwm, syringe cwjmem yog siv. Ntawm kev muag koj tuaj yeem pom ntau hom tshuaj: Humalog Mix 25 thiab Humalog Mix 50. Thawj qhov kev xaiv muaj 25% Lizpro insulin (ua yeeb yam luv luv) thiab 75% Lizpro insulin ncua (nruab nrab ntev), qhov thib ob ntawm cov tshuaj hormones muaj ob qho tib si feem sib luag.

Cov tshuaj muaj pes tsawg leeg suav nrog cov khoom siv ntxiv: glycerol, metacresol, zinc oxide, sodium hydrogen phosphate heptahydrate, hydrochloric acid (sodium hydroxide tov) thiab dej.

Lub hauv paus ntsiab lus ntawm kev khiav haujlwm

Ultra-luv-ua yeeb yam insulin pib ua haujlwm ua ntej lub cev muaj sijhawm los nqus thiab ua cov khoom noj uas tau txais hauv qabzib. Cov yeeb tshuaj zoo li no tau siv ntau dua yog tias nws yuav tsum tau ceev nrawm rau cov ntshav qab zib kom ntau, thaum nws cov qib siab tsis tau coj mus rau kev txhim kho cov teeb meem. Txawm li cas los xij, muaj qee kis muaj peev xwm hais txog kev tiv thaiv luv luv txawm hais los ntawm cov neeg mob uas ua raws li kws kho mob cov lus pom zoo thiab ua lub neej noj qab nyob zoo. Piv txwv, nrog lub ntsej muag zoo hauv cov piam thaj thaum kev ntxhov siab.

Thaum siv cov tshuaj insulin ultrashort, nws yog ib qho tseem ceeb kom nco ntsoov tias nws yog ob peb zaug muaj zog dua li cov tshuaj tiv thaiv ntawm cov yeeb yam luv-luv. 1 ntu ntawm Humalog tuaj yeem txo cov ntshav qab zib 2.5 zaug sai dua 1 ntu ntawm luv luv insulin. Txawm li cas los xij, txhawm rau kev kho tshuaj kom ua txoj haujlwm tau zoo, nws yog qhov tsim nyog los xaiv txoj cai ntau npaum.

Qhov zoo thiab qhov tsis zoo

Txhua hom tshuaj insulin nws muaj qhov zoo thiab kev pom zoo. Qhov ua tau zoo ntawm cov tshuaj tau raug soj ntsuam los ntawm qhov siab tshaj plaws ntawm lawv cov txiaj ntsig rau cov ntshav thiab tus nqi ntawm cov qis pauv hauv insulin. Lub humalogue yog yam ntxwv los ntawm lub ncov siab dua. Nws pib ua nyob rau hauv 15 feeb tom qab noj. Yog li ntawd, nws pom zoo kom nkag mus rau 15-20 feeb ua ntej noj mov.

Qhov ceev ntawm cov tshuaj yog suav hais tias yog ib qho ntawm nws lub ntsiab tseem ceeb. Qhov ntsuas no yog qhov tshwj xeeb tshaj plaws rau cov neeg uas tsis tau hno qhov xav tau. Lub sijhawm thiab siv ntawm kev ua yog nyob ntawm qhov chaw tswj hwm tshuaj, kev noj qab haus huv txhua tus, tus yam ntxwv thiab kev siv lub cev. Cov tshuaj Insulin Humalog muaj qhov nqus tau zoo heev. Nws qhov siab tshaj plaws tau muab sau cia 30-60 feeb tom qab kev tswj hwm.

Ntawm lwm qhov zoo ntawm cov tshuaj tuaj yeem sau tseg:

• lub peev xwm los txo tsawg tus naj npawb ntawm manifestations ntawm nocturnal glycemia,
• lub peev xwm los tsim cov leeg nqaij los ntawm kev ua kom cov ntsiab lus ntawm cov roj ntsha thiab ua kom cov protein synthesis zoo,
• kev ua kom nrawm ntawm cov txheej txheem kev noj ntawm cov amino acids.

Qhov tsis zoo tshaj plaws Humalog yog qhov tsis txaus ntseeg. Txhawm rau xam seb cov nyhuv ntawm cov tshuaj rau hauv lub cev txuas ntxiv lossis tau dhau los, nws yog qhov yuav tsum tau ua ntsuas kev ntsuas nrog glucometer. Qhov no tsis yooj yim ib txwm.

Taw qhia cov kev cai

Insulin Humalog tuaj yeem raug tswj hwm nyob rau hauv 2 txoj kev: subcutaneously thiab intravenously. Kev tswjfwm subcutaneous yog nyob rau hauv hom kev txhaj tshuaj, Txoj kev lis ntshav, lossis nrog lub twj tso kua mis. Tso dej mus rau cov kev tswjhwm yog tsuas yog ua qhov kawg. Txhawm rau ua qhov no, koj tuaj yeem siv thaj tsam ntawm lub duav, lub xub pwg nyom, plab thiab pob tw. Nws tsis pom zoo kom tswj cov tshuaj hauv tib qho chaw.

Txhawm rau txhaj tshuaj insulin kom raug, koj yuav tsum ua raws li qee txoj cai.

1. Ua ntej kev tswj hwm, nco ntsoov xyuas kom meej tias cov kev daws teeb meem kom pom tseeb, tsis muaj impurities, turbidity thiab sediment.
2. Ntxuav koj ob txhais tes thiab txiav txim siab qhov chaw qhia. Kho nws nrog antiseptic.
3. Tshem tawm ntawm txoj hlua tiv thaiv los ntawm rab koob. Rub los yog hau daim tawv nqaij rau hauv cov pob taws thiab kho nws.
4. Ntxig lub koob raws li cov lus qhia rau kev siv thiab nias lub pob nyem.
5. Tshem tawm rab koob.Nias qhov txhaj tshuaj maj mam. Tsis txhob txhuam los yog zaws nws.
6. Kaw cov koob siv nrog lub hau. Tsis tua thiab muab pov tseg.
7. Kaw cov xaum xaum xaum nrog lub hau thiab muab tso rau hauv qhov chaw ntim.

Yog tias koj siv Humalog Insulin thawj zaug, ua tib zoo nyeem phau ntawv qhia tus neeg siv ua ntej kev tswj hwm. Yog tias koj muaj lus nug, tham nrog koj tus kws kho mob.

Npaum li cas thiab ntau npaum li cas los ntaus nws?

Humalog sai dua li lwm cov tshuaj tuaj yeem kho cov ntshav qab zib kom ntshav khov. Yog li ntawd, nws yog qhov zoo tshaj kom muaj nws nrog koj thaum muaj xwm txheej. Txawm li cas los xij, qee tus neeg mob ntshav qab zib tau kam siv cov tshuaj insulin luv luv thiab ultrashort. Yog tias koj tswj hwm koj cov piam thaj hauv cov ntshav qis nrog kev noj zaub mov kom tsawg, koj tuaj yeem yuav los ntawm cov yeeb tshuaj luv luv.

Ntev npaum li cas rau kev txhaj tshuaj?

Txhua qhov txhaj ntawm cov tshuaj Humalog yuav siv li 4 teev. Tus mob ntshav qab zib uas ua raws li yuav tsum tau txhaj tshuaj insulin tsawg kawg. Nws feem ntau yuav tsum tau diluted kom raug txhaj ib koob uas tsawg dua 0.5-1 ib pawg. Tib neeg cov lus qhia tuaj yeem ua tsis tau tsuas yog rau cov menyuam yaus uas muaj ntshav qab zib hom 1, tab sis kuj yog rau cov neeg mob laus. Vim tias nws yog ib cov tshuaj uas muaj zog heev. Thaum siv cov tshuaj tsawg kawg, insulin nres ua haujlwm sai dua li teev hauv cov lus qhia ntawm nom tswv. Tej zaum qhov kev txhaj tshuaj yuav tas rau hauv 2.5-3 teev.

Tom qab txhaj txhua yam ntawm kev npaj ultrashort, ntsuas ntshav qab zib kom tsis muaj ntxov dua 3 teev tom qab. Vim tias txog lub sijhawm no, cov koob tshuaj insulin tsis muaj sijhawm tsis txaus los qhia nws cov nyhuv tag nrho. Raws li txoj cai, cov ntshav qab zib tau muab qhov kev txhaj tshuaj ntawm cov insulin ceev, noj, thiab tom qab ntawd ntsuas ntsuas qab zib ua ntej noj mov tom ntej. Tsuas yog nyob hauv cov xwm txheej uas tus neeg mob hnov. Hauv cov xwm txheej zoo li no, koj yuav tsum tau soj ntsuam tam sim ntawd txog qib piam thaj hauv cov ntshav thiab, yog tias tsim nyog, nqis tes ua.

Dab tsi yog qhov sib txawv ntawm Humalog thiab Humalog Mix?

Qhov nruab nrab tshuaj tiv thaiv Hagedorn (NPH), uas ua rau qeeb qis qis ntawm kev ua haujlwm ntawm insulin, tau ntxiv rau Humalog Mix 25 thiab 50. Cov insulin no sib txawv hauv cov ntsiab lus ntawm NPH. Cov khoom ntau dua, qhov ntau txuas ntxiv ua ntawm kev txhaj tshuaj. Cov tshuaj no tseem nrov vim tias lawv tuaj yeem txo cov naj npawb ntawm txhua hnub ntawm kev txhaj tshuaj, ua kom yooj yim rau kev tswj hwm ntawm kev siv tshuaj insulin. Txawm li cas los xij, lawv muab tsis tau kev tswj ntshav qab zib kom zoo. Yog li, lub vev xaib xaib tsis pom zoo siv lawv li.

Nyeem txog kev tiv thaiv thiab kev kho mob ntawm cov teeb meem:

Cov tshuaj insulin twg zoo dua: Humalog lossis NovoRapid?

Tej zaum yuav tsis muaj cov ntaub ntawv raug los teb cov lus nug no, uas feem ntau tau nug los ntawm cov neeg mob. Vim tias ntau hom insulin cuam tshuam rau txhua tus ntshav qab zib ib tus zuj zus. Zoo li Humalog, lawv muaj ntau tus kiv cua. Raws li txoj cai, cov neeg mob txhaj tshuaj uas lawv tau pub dawb.

Kev fab tshuaj yuam kom qee leej hloov los ntawm ib hom tshuaj insulin mus rau lwm tus. Peb rov hais dua, yog tias soj ntsuam sai li insulin ua ntej noj mov, nws yog qhov zoo dua los siv cov yeeb tshuaj luv luv, piv txwv li, dua li ntawm ultrashort Humalog, NovoRapid lossis Apidra. Yog tias koj xav xaiv qhov zoo tshaj plaws ntawm kev txuas ntxiv thiab ceev insulin, ces koj tsis tuaj yeem ua yam tsis muaj kev sim siab thiab qhov tsis raug.

Cov tshuaj ntxiv ntawm cov tshuaj insulin Humalog (lispro) - cov no yog cov tshuaj thiab. Cov qauv ntawm lawv cov lwg me me nws txawv, tab sis rau kev coj ua nws tsis txawv. thov tias Humalog ua nrawm dua thiab muaj zog dua nws cov neeg ua haujlwm. Txawm li cas los xij, tsis yog txhua tus neeg mob lees paub cov ntaub ntawv no. Ntawm cov ntawv sib tham ntawm Lavxias-hais txog tus mob ntshav qab zib, koj tuaj yeem nrhiav cov lus tsis txaus ntseeg.

Cov neeg mob uas muaj ntshav qab zib hom 1 thiab ntshav qab zib hom 2 uas tau soj ntsuam zoo yuav sim hloov cov tshuaj insulin lispro nrog cov tshuaj tiv thaiv luv luv. Piv txwv li, ntawm. Saum toj no nws tau sau hauv kev nthuav dav yog vim li cas qhov no tsim nyog ua. Ntxiv mus, luv luv insulin yog pheej yig dua. Vim tias nws tau nkag mus rau tom khw ntau xyoo dhau los.

Luv tib neeg lub cev insulin pib nws txoj haujlwm 30-45 feeb tom qab nws muab nkag rau hauv lub cev.Muaj cov nplaim ultra-luv ntau yam ntawm cov tshuaj pleev insulin, uas ua haujlwm tom qab 10 feeb. Cov no suav nrog kev hloov kho tshiab ntawm tib neeg cov tshuaj insulin: Apidra, Novo-Rapid thiab Humalog. Cov qauv ntawm ntuj insulin, ua tsaug rau cov kua mis zoo dua tuaj, tuaj yeem txo cov ntshav qabzib cov ntshav yuav luag tam sim ntawd tom qab nkag mus rau hauv tus neeg mob lub cev nrog ntshav qab zib.

Dab tsi yog insulin cuav

Cov tshuaj pleev insulin tau tsim tshwj xeeb los ua kom sai sai kom muaj cov ntshav khov nyob rau hauv qab zib uas ua los ntawm kev ua txhaum ntawm cov zaub mov nruj ntawm cov neeg muaj mob Raws li kev coj ua qhia, nws tsis tuaj yeem ua nws 100 feem pua, vim tias thaum koj siv cov khoom noj txwv tsis pub noj ntshav qab zib, cov ntshav qabzib tuaj yeem nce siab ntau heev.

Txawm hais tias muaj cov kev hloov pauv nyob rau yam piam thaj, cov zaub mov uas tsis muaj zaub mov rau lub cev tsawg yuav tsis muaj kev cia siab, vim tias kev nce ntxiv hauv cov ntshav qab zib yuav cuam tshuam rau tag nrho cov duab ntawm chav kawm.

Ultrashort insulin yog siv los sai sai cov piam thaj kom nyob rau qib ib txwm, thiab tseem qee zaum ua ntej noj mov. Qhov no yog qhov tsim nyog nyob rau hauv cov mob uas cov ntshav qab zib nce qabzib sai tom qab noj mov.

Tus kws kho mob sau ntawv rau cov neeg mob ntshav qab zib hom 1 lossis hom 2 nrog kev tswj tus kheej ntawm lawv cov ntshav qabzib. Tus txheej txheem no yuav tsum tau nqa tawm tsawg kawg ib lub lim tiam thiab tsuas yog tom qab lub sijhawm no nws yuav muaj peev xwm los txiav txim siab txog hom tshuaj insulin twg yuav tsum tau txhaj, nws cov koob tshuaj thiab lub sijhawm twg. Nws tsis tuaj yeem pom zoo siv cov txheej txheem thoob ntiaj teb, vim tias nyob rau hauv txhua kis nws yuav tshwj xeeb thiab tus kheej.

Kev kho mob insulin ua haujlwm li cas?

Yog tias peb tham txog ultra-luv version ntawm insulin, ces nws ua haujlwm ntau dua li lub cev mob pib hloov cov protein mus rau hauv cov ntshav qabzib. Vim li no, cov neeg uas ua raws li cov zaub mov uas tsis muaj carbohydrate tsawg hauv qhov ua tau zoo thiab muaj txiaj ntsig zoo tuaj yeem siv cov insulin luv luv ua ntej noj mov.

Nws yuav tsum tau nkag rau hauv lub cev li 45 feeb ua ntej noj mov. Lub sijhawm tsis tau hais meej, vim tias txhua tus neeg mob yuav tsum, los ntawm kev sim thiab qhov yuam kev, nrhiav lub sijhawm zoo tshaj plaws rau qhov kev txhaj tshuaj. Tib neeg cov kua dej yuav ua haujlwm rau 5 teev, vim tias nws yog nyob rau lub sijhawm no uas txhua yam zaub mov zom thiab muaj suab thaj hauv cov hlab ntshav.

Raws li rau hloov kho ua kom lub cev tiv thaiv kab mob, nws yog qhov tsim nyog nyob rau hauv quab yuam majeure kom sai sai cov piam thaj hauv ib tus neeg mob. Qhov no yog qhov tseem ceeb heev, vim tias nyob rau theem nws tau nce siab ntau qhov cuam tshuam txog kev mob ntshav qab zib mellitus thiab qhov tshwm sim ntawm nws cov tsos mob. Vim li no, nws yog qhov tsis tsim nyog yuav tsum tau siv cov insulin zoo tib yam.

Txhais cov ntsiab lus:

1. Rau cov neeg uas muaj mob ntshav qab zib hom 2 thiab lawv cov ntshav qab zib yuav tsawg zuj zus, nws tsis tas yuav txhaj tshuaj insulin ntxiv rau kom txo cov ntshav qab zib.
2. Txawm hais tias koj ua raws li tus kws kho mob lub tswv yim hais txog kev noj zaubmov ntau ntau, kev noj zaub mov ntawm tib neeg cov tshuaj insulin kuj yuav yooj yim. Yog tias cov piam thaj dheev dhia, tom qab ntawv insulin ultra-luv luv yuav txo qis nws ob peb zaug sai dua. Nws ua raws los ntawm qhov no tias cov teeb meem ntawm cov chav kawm ntawm cov piam thaj yuav tsis muaj peev xwm pib ua lawv cov kev ua kom.
3. Qee qhov xwm txheej, koj tsis tuaj yeem ua raws li txoj cai ntawm tos 45 feeb ua ntej noj mov, txawm li cas los xij, qhov no yog qhov kev zam.

Koj yuav tsum nco ntsoov tias ultrashort insulins muaj ntau zaus ntau dua li cov luv. Kev hais lus nyob rau hauv tus lej, 1 chav ntawm Humalog insulin yuav tuaj yeem txo cov piam thaj 2,5 zaug sai dua 1 ntu ntawm luv luv insulin.

Lwm hom npe muaj cov luv luv insulin "Apidra" thiab "Novo-nrawm" - lawv ceev 1.5 npaug. Cov nuj nqis no tsis tuaj yeem coj mus ua qhov tsis muaj tseeb, vim tias qhov no piv qhia.Qhov tseeb paub tus duab no yog ua tau tsuas yog hauv kev coj ua hauv txhua kis. Tib yam siv rau kev siv ntawm cov tshuaj insulin ultrashort. Nws tuaj yeem qis dua qis dua qhov sib npaug ntawm luv luv insulin.

Yog tias peb piv "Humalog", "Apidra" thiab "Novo-Rapid", ces nws yog thawj cov tshuaj uas yeej los ntawm kev ceev ntawm kev txiav txim txog ib zaug txhua 5.

Lub ntsiab zoo thiab qhov tsis zoo ntawm cov insulin

Ntau cov kev tshawb fawb txog kev kho mob tau qhia tias txhua yam ntawm insulin tuaj yeem muaj ob qho zoo thiab qhov tsis zoo.

Yog tias peb tham txog tib neeg luv luv insulin, tom qab ntawd qhov kawg ntawm nws cov txiaj ntsig rau cov ntshav ntawm ntshav qab zib yog tom qab tshaj thaum txhaj nrog qhov kev xaiv ultrashort, tab sis tib lub sijhawm, nws cov qib theem poob sai dua thiab tuaj yeem hloov pauv tau.

Vim qhov tseeb tias Humalog muaj lub ncov siab dua, nws tsis yooj yim rau qhov muaj peev xwm ua ntej kwv yees cov nyiaj ntawm cov carbohydrates uas tuaj yeem haus kom cov piam thaj hauv cov neeg mob cov ntshav tseem nyob rau theem qub. Cov nyhuv du ntawm cov insulin luv luv pab txhawb qhov zoo tshaj plaws ntawm kev nqus ntawm cov tseem ceeb ntawm cov zaub mov, tau muab cov khoom noj tshwj xeeb rau kev tswj cov ntshav qabzib tau pom.

Yog tias peb saib ntawm qhov teeb meem no ntawm qhov tod tes, tom qab ntawd txhua zaus ua ntej noj nws yog qhov teeb meem heev los tos 45 feeb rau insulin luv los pib qhov kev nqis tes ua. Yog tias qhov nuance no tsis raug coj mus rau hauv tus account, ces cov piam thaj hauv cov ntshav yuav loj hlob sai dua li cov tshuaj txhaj yuav pib ua haujlwm.

Synthetic lawm tseem tuaj yeem txo cov insulin tom qab 10-15 feeb tom qab nws txhaj. Qhov no, tau kawg, nws yooj yim dua, tshwj xeeb tshaj yog tias noj mov tsis tau noj raws li lub sijhawm tshwj xeeb.

Nyob rau hauv lub neej tiag tiag, nws hloov tawm tias luv luv cov neeg insulin ua haujlwm ntau yam ruaj khov dua li ntawm ultrashort. Qhov kawg yuav tsis tuaj yeem paub tseeb, txawm hais tias nws siv qhov ntau thiab tsawg tshaj plaws, tsis txhob hais txog cov rooj plaub no thaum tus neeg mob txhaj lawv tus kheej nrog cov koob tshuaj loj kawg.

Nws tseem yuav tsum tau nco ntsoov hais tias txhim kho insulin yog ob peb zaug muaj zog dua li tib neeg. Piv txwv li, 1 koob tshuaj ntawm Humaloga yog kwv yees li ib feem peb ntawm koob tshuaj insulin luv luv, thiab 1 koob tshuaj Apidra thiab Novo-Rapida yog kwv yees li 2/3. Txawm li cas los xij, nws yog ib qho tseem ceeb kom paub tias cov nuj nqis no tsuas yog kwv yees, thiab lawv txoj kev txhim kho tsuas yog ua tiav los ntawm kev sim.

Muaj qee tus neeg mob ntshav qab zib uas muaj qhov nqus ntawm cov insulins luv luv ntev ntev. Lub sijhawm no tuaj yeem sib txawv li ntawm 60 feeb mus rau 1.5 teev. Nyob rau hauv qhov xwm txheej zoo li no, nws yog qhov teeb meem heev kom noj zaub mov nyob hauv kev nplij siab. Rau cov neeg mob zoo li no nws pom zoo kom siv cov roj ntsha ceev tshaj plaws ntawm cov tshuaj Humulin insulin, txawm li cas los xij, qhov xwm txheej ntawm lub caij nyoog ntev yog qhov tsawg.

Tsuas tshuaj thiab tswj hwm

Cov koob tshuaj ntawm Humalog® yog txiav txim los ntawm tus kws kho mob ntawm tus kheej, nyob ntawm seb cov concentration ntawm cov piam thaj hauv cov ntshav. Qhov tseeb ntawm kev muab tshuaj insulin yog tus kheej.

Kev noj tshuaj Humalog® tuaj yeem muab ua ntej noj mov. Yog tias tsim nyog, Humalog® tuaj yeem muab rau siv tam sim ntawd tom qab noj mov.

Qhov ntsuas kub ntawm cov tshuaj tso cai yuav tsum nyob ntawm chav sov.

Humalog® yuav tsum tau txhaj tshuaj raws li kev txhaj tshuaj subcutaneous lossis raws li kev ncua subcutaneous infusion siv lub twj tso kua mis. Yog tias tsim nyog (ketoacidosis, mob hnyav, lub sijhawm ntawm kev ua haujlwm lossis sijhawm hla sijhawm), Humalog® kev npaj kuj tseem tuaj yeem siv tshuaj pleev ib ce.

Subcutaneously yuav tsum txhaj rau hauv lub xub pwg, ncej puab, pob tw los sis plab. Qhov chaw txhaj tshuaj yuav tsum tau hloov chaw kom tib qhov chaw siv tsis ntau tshaj li 1 zaug hauv ib hlis.

Nrog kev tswj hwm subcutaneous ntawm Humalog® kev npaj, kev saib xyuas yuav tsum tau saib xyuas kom tsis txhob txais cov tshuaj rau hauv cov hlab ntshav. Tom qab txhaj tshuaj, qhov chaw txhaj tshuaj yuav tsum tsis txhob zaws.Tus neeg mob yuav tsum tau kawm siv cov txheej txheem kev txhaj tshuaj kom raug.

Cov lus qhia rau kev tswj hwm tshuaj yeeb tshuaj Humalog®
Npaj rau kev qhia
Qhov daws ntawm Humalog® npaj yuav tsum yog pob tshab thiab xim tsis muaj xim. Tsis txhob siv cov tshuaj Humalog® yog tias nws hloov tawm ntawm cov huab, thooj, tawv xim, lossis cov khoom tawg tau pom kev pom.

Thaum txhim kho lub taub ntim hauv cov koob txhaj tshuaj, txuas lub koob thiab txhaj tshuaj insulin, ua raws li cov chaw tsim khoom cov lus qhia uas suav nrog txhua tus xaum xaum xaum.

Kev tswj hwm txoj cai
1. Ntxuav koj txhais tes.
2. Xaiv qhov chaw txhaj tshuaj.
3. Npaj daim tawv nqaij ntawm qhov chaw txhaj tshuaj raws li kws kho mob pom zoo.
4. Tshem tawm ntawm lub hau sab nraud los ntawm rab koob.
5. Xauv cov tawv nqaij.
6. Tso lub koob txhaj tshuaj subcutaneously thiab ua qhov kev txhaj tshuaj raws li cov lus qhia siv kev siv tus xaum xim.
7. Tshem tawm rab koob thiab maj mam nyem qhov chaw txhaj tshuaj nrog paj rwb pas nrig rau ob peb feeb. Tsis txhob txhuam thaj chaw txhaj tshuaj.
8. Siv lub hau thaiv sab nraud ntawm rab koob, rho tawm rab koob thiab pov tseg.
9. Muab lub hau ntim rau ntawm tus cwj mem.

Rau qhov npaj ntawm Humalog® hauv QuickPen ™ koob txhaj.
Ua ntej muab cov tshuaj insulin, koj yuav tsum nyeem QuickPen ™ Syringe cwj mem qhia siv.

Tso dej insulin
Kev txhaj tshuaj tiv thaiv ntawm Humalog® kev npaj yuav tsum ua raws li kev siv tshuaj txhaj rau txoj kev txhaj tshuaj, piv txwv, txhaj tshuaj bolus tswj hwm lossis siv cov txheej txheem infusion. Hauv qhov no, feem ntau nws yog ib qho tsim nyog los tswj cov kev xav ntawm cov piam thaj hauv cov ntshav.

Lub tshuab ua ke nrog cov ntsiab lus los ntawm 0.1 IU / ml rau 1.0 IU / ml tshuaj insulin lispro hauv 0.9% sodium chloride tov lossis 5% dextrose daws yog ruaj khov nyob rau chav sov li 48 teev.

Subcutaneous insulin Txoj Kev lis ntshav nrog lub tshuab nqus dej insulin
Rau Txoj kev lis ntshav ntawm Humalog® kev npaj, twj yuav siv - tshuab rau kev nruam subcutaneous tswj hwm ntawm insulin nrog CE cim. Ua ntej muab cov lyspro tshuaj insulin, nco ntsoov tias lub tshuab nqus tshwj xeeb. Koj yuav tsum nruj me ntsis ua raws cov lus qhia uas tuaj nrog lub twj tso kua mis. Siv lub taub dej haum thiab kav raj rau lub twj tso kua mis. Txoj kev lis ntshav ntawd yuav tsum hloov raws li cov lus qhia tau muab nrog kev teeb tsa Txoj kev lis ntshav. Yog tias qhov tshuaj tiv thaiv hypoglycemic tshwm sim, Txoj kev lis ntshav yog nres mus txog thaum rov ua ntu. Yog tias muaj cov ntshav qabzib nyob hauv cov ntshav tsawg, tom qab ntawd koj yuav tsum qhia koj tus kws kho mob txog qhov no thiab txiav txim siab txo lossis txo qhov insulin infusion. Ib lub twj tso kua mis tsis ua hauj lwm lossis kev txhaws hauv txoj kev lis ntshav tuaj yeem ua rau nce ntxiv hauv cov ntshav ntshav qabzib. Yog tias lub sijhawm ua txhaum cai ntawm kev ua txhaum ntawm kev muab cov tshuaj insulin, koj yuav tsum ua raws li cov lus qhia thiab yog tias tsim nyog, qhia rau tus kws kho mob. Thaum siv lub twj tso kua mis, npaj Humalog should yuav tsum tsis txhob sib xyaw nrog lwm cov insulins.

Sab sij huam

Kev mob ntshav siab yog qhov tshwm sim ntau tshaj plaws hauv kev kho mob rau cov neeg mob ntshav qab zib nrog cov tshuaj insulin. Kev mob ntshav khov ntau heev tuaj yeem ua rau tsis nco qab (hypoglycemic coma) thiab, tshwj tsis yog rau kev tuag.

Cov neeg mob tuaj yeem yuav pom kev ua xua nyob rau thaj tsam ntawm daim ntawv liab, o, lossis khaus ntawm qhov chaw txhaj tshuaj. Feem ntau, cov tsos mob no ploj mus li ntawm ob peb hnub lossis ob peb lim tiam. Qee qhov xwm txheej, cov kev coj ua no tuaj yeem yog los ntawm cov laj thawj tsis cuam tshuam rau cov tshuaj insulin, piv txwv li, tawv nqaij nrog lub ntsej muag ntxuav los yog siv tshuaj tsis raws cai.

Tsis tshua muaj, muaj kev tsis haum rau lub cev feem ntau tshwm sim uas yog khaus thoob plaws lub cev, khaus khaus, angioedema, kub taub hau, ua pa luv, txo ntshav siab, tachycardia, thiab tawm hws tuaj yeem tshwm sim. Cov teeb meem nyhav ntawm kev tsis haum suav nrog tuaj yeem ua rau tuag taus.

Lipodystrophy tuaj yeem tsim kho ntawm thaj chaw txhaj tshuaj.

Cov lus tshwm sim:
Cov kab mob ntawm kev txhim kho ntawm edema tau txheeb xyuas, feem ntau nrog kev ceev nrawm ntawm cov ntshav qabzib hauv qab los ntawm kev siv tshuaj insulin ntau ntxiv nrog kev pib tsis txaus siab glycemic tswj.

Kev cuam tshuam nrog lwm yam tshuaj

Qhov mob ntawm cov nyhuv ntshav tsawg yog txo thaum siv ua ke nrog cov tshuaj hauv qab no: tshuaj tiv thaiv qhov ncauj, glucocorticosteroids, iodine-muaj cov thyroid hormones, danazol, beta2-adrenergic agonists (piv txwv li, ribodrin. Salbutamol, terbutaline), thiazide diuretics, ua yeeb yam, isoprotic, isoprotic phenothiazine.

Qhov mob hnyav ntawm cov nyhuv ntshav hypoglycemic nce nrog rau cov tshuaj sib xyaw nrog cov tshuaj hauv qab no: beta-blockers, ethanol thiab ethanol-muaj cov tshuaj, anabolic steroids, fenfluramine. guanethidine, tetracyclines, tshuaj tiv thaiv hypoglycemic hauv qhov ncauj, salicylates (e.g. acetylsalicylic acid), tshuaj tua kab mob sulfonamide. qee cov tshuaj tiv thaiv kab mob (monoamine oxidase inhibitors, serotonin reuptake inhibitors), angiotensin hloov enzyme inhibitors (captopril, enapril), octreotide, angiotensin II receptor antagonists.

Yog tias koj yuav tsum siv lwm cov tshuaj, ntxiv rau insulin, sab laj koj tus kws kho mob.

Cov lus qhia tshwj xeeb

Hloov chaw ntawm tus neeg mob rau lwm hom lossis kev npaj tshuaj insulin yuav tsum tau ua nyob rau hauv kev saib xyuas mob nkeeg nruj me ntsis. Cov kev hloov hauv kev ua, hom (tus tsim khoom), hom (tsis tu ncua, NPH, thiab lwm yam), hom (tsiaj, tib neeg, tib neeg insulin analogue) thiab / lossis txoj kev tsim tawm (DNA recombinant insulin lossis insulin ntawm tsiaj keeb kwm) tuaj yeem ua rau qhov xav tau rau qhov hloov kho koob tshuaj.

Hauv cov neeg mob hypoglycemic tshua tom qab hloov los ntawm tsiaj los ntawm cov tshuaj insulin rau tib neeg insulin, cov tsos mob thaum ntxov ntawm hypoglycemia yuav tsis tshua pom los yog txawv ntawm cov kev paub dhau los ntawm lawv cov insulin yav dhau los. Kev tiv thaiv tsis zoo hypo- thiab hyperglycemic tej yam kev mob tuaj yeem ua rau tsis nco qab, tsis nco qab, lossis tuag.

Nws yuav tsum tau yug hauv siab tias lub chaw muag tshuaj ntawm analogues ntawm tib neeg lub cev sai insulin yog tias yog tias hypoglycemia tsim, nws tuaj yeem tsim tom qab kev txhaj tshuaj ntawm qhov ua haujlwm sai ntawm tib neeg cov tshuaj insulin ua ntej tshaj nyob rau hauv rooj plaub ntawm soluble tib neeg cov kua dej.

Rau cov neeg mob tau txais cov tshuaj insulins luv luv thiab hauv paus, nws yog qhov tsim nyog yuav tsum xaiv lub koob tshuaj ntawm ob qho insulins thiaj li ua tiav qhov zoo tshaj plaws ntawm cov piam thaj hauv cov ntshav thaum nruab hnub, tshwj xeeb tshaj yog thaum tsaus ntuj lossis hauv plab.

Cov tsos mob ua ntej ntawm lub ntsej muag hypoglycemia tuaj yeem hloov pauv thiab tsis tshua tau hais nrog lub sijhawm ntev ntawm mob ntshav qab zib mellitus, mob ntshav qab zib neuropathy lossis kho nrog tshuaj xws li beta-blockers.

Kev noj tshuaj tsis txaus lossis tsis ncua kev kho mob, tshwj xeeb tshaj yog rau cov neeg mob ntshav qab zib hom 1 mob ntshav qab zib, tuaj yeem ua rau tus mob hyperetcemia thiab ntshav qab zib ketoacidosis - cov mob uas muaj peev xwm tuag taus rau tus neeg mob.

Txoj kev xav tau cov tshuaj insulin tuaj yeem txo qis dua thaum lub raum tsis ua haujlwm, nrog rau cov neeg mob hepatic tsis txaus ua rau muaj kev txo qis hauv cov txheej txheem ntawm gluconeogenesis thiab insulin metabolism. Txawm li cas los xij, nyob rau hauv cov neeg mob mob siab tsis ua haujlwm ntev, muaj peev xwm tiv thaiv insulin ntau dua tuaj yeem ua rau muaj kev nce ntxiv hauv insulin.

Txoj kev xav tau cov tshuaj insulin tuaj yeem nce ntxiv nrog qee qhov mob lossis kev ntxhov siab.

Kev hloov kho ntawm cov koob tshuaj insulin tej zaum yuav tsum tau ua thaum cov neeg mob nce kev tawm dag zog lossis thaum hloov kev noj zaub mov zoo. Kev tawm dag zog tuaj yeem ua rau muaj kev pheej hmoo ntawm cov ntshav qab zib tsawg dua.

Thaum siv cov tshuaj insulin nyob rau hauv kev sib xyaw nrog cov tshuaj ntawm thiazolidinedione pab pawg, qhov kev pheej hmoo ntawm kev txhim kho edema thiab mob plawv sai dua, tshwj xeeb tshaj yog nyob rau cov neeg mob uas muaj kab mob ntawm cov hlab plawv thiab muaj cov kev pheej hmoo ua rau mob plawv tsis ua haujlwm.

Kev siv cov Humalog® nyob rau hauv cov menyuam yaus es tsis txhob tiv thaiv tib neeg cov tshuaj insulin yog qhov zoo dua rau cov teeb meem no thaum tsim nyog yuav tsum pib ua sai sai ntawm insulin (piv txwv li, kev qhia ntawm insulin tam sim ntawd ua ntej noj mov).

Txhawm rau zam kom kis tau tus mob kis tau, txhua daim cartridge / koob txhaj tshuaj yuav tsum tau siv los ntawm tsuas yog ib tus neeg mob, txawm tias yuav raug hloov rab koob.

Humalog® cartridges yuav tsum tau siv nrog CE-daim ntawv lo koob txhaj tshuaj raws li cov lus qhia ntawm lub tuam txhab ua khoom siv.

Cuam tshuam rau kev muaj peev xwm tsav tsheb thiab tswj cov tshuab

Thaum tus neeg lub qog ntshav qab zib, qhov kev mloog zoo thiab ceev ntawm lub hlwb kev xav yuav txo qis. Qhov no tuaj yeem txaus ntshai nyob rau hauv qhov xwm txheej uas qhov peev xwm tshwj xeeb tshaj yog tsim nyog (piv txwv, tsav tsheb lossis kev siv tshuab).

Cov neeg mob yuav tsum tau qhia rau kev ceev faj kom tiv thaiv kev mob ntshav qab zib thaum tsav tsheb thiab tswj cov tshuab. Qhov no yog qhov tshwj xeeb tshaj yog rau cov neeg mob uas cov tsos mob me lossis tsis tuaj, ua ntej ntawm cov ntshav ntog ntshav qab zib lossis nrog rau kev txhim kho ntshav nce siab ntau ntau. Hauv cov xwm txheej zoo li no, tus kws kho mob yuav tsum ntsuas qhov ua tau ntawm tus neeg mob tsav tsheb thiab tswj cov twj.

Cia rau cov neeg mob

Khaws rau hauv tub yees ntawm qhov kub ntawm 2-8 ° C.
Cov tshuaj uas siv hauv daim cartridge / koob txhaj tshuaj yuav tsum tau muab cia rau hauv chav tsev tsis kub tshaj 30 ° C rau tsis pub ntau tshaj 28 hnub.
Tiv thaiv los ntawm tshav ntuj ncaj qha thiab kub. Tsis txhob pub kom khov.
Khaws tsis ncav cuag ntawm cov menyuam yaus.

Npe thiab chaw nyob ntawm cov xaib ntau lawm

Kev tsim cov ntawv tshuaj tiav thiab cov ntim thawj:
"Lilly Fabkis." Fabkis (cartridges, QuickPen ™ syringe cwjmem)
2 Ru du Colonel Lilly, 67640 Fegersheim, Fab Kis

Kev lag luam theem ob thiab kev tshaj tawm zoo:
Lilly Fabkis, Fab Kis
2 Ru du Colonel Lilly, 67640 Fegersheim
lossis
Eli Lilly thiab Tuam Txhab, Tebchaws Asmeskas
Indianapolis, Indiana. 46285 (QuickPen ™ syringe Cwjmem)
lossis
JSC OPTAT, Russia
157092, Kostroma cheeb tsam, Susaninsky koog tsev kawm ntawv, nrog. Qaum Qaum teb, microdistrict. Kharitonovo

Thov nyeem Daim Ntawv Qhia QuickPen ™ Syringe Cwj mem rau Siv ua ntej Siv

Nyeem phau ntawv no ua ntej siv insulin thawj zaug. Txhua zaus koj tau txais pob tshiab nrog QuickPen-syringe cwjmem, koj yuav tsum nyeem cov lus qhia rau kev siv dua, raws li nws yuav muaj cov ntaub ntawv tshiab. Cov ntaub ntawv muaj nyob hauv cov lus qhia tsis hloov pauv kev sib tham nrog koj tus kws kho mob txog tus kab mob thiab kev kho koj.

Lub QuickPen-Syringe Cwj mem ("Cwj mem kua") yog cov khoom siv pov tseg, cov xaum xaum xoos ntim muaj 300 units ntawm insulin. Nrog ib tus cwj mem nkaus xwb, koj tuaj yeem siv ntau lub koob tshuaj insulin. Siv tus cwj mem no, koj tuaj yeem nkag mus rau koob tshuaj nrog qhov tseeb ntawm 1 chav. Koj tuaj yeem nkag los ntawm 1 txog 60 units ib zaug kev txhaj tshuaj. Yog tias koj cov tshuaj ntau dua 60 units, koj yuav tsum tau txhaj ntau dua li ib koob. Nrog txhua qhov kev txhaj tshuaj, lub piston tsuas yog txav me ntsis, thiab koj tuaj yeem tsis pom ib qho kev hloov pauv ntawm nws txoj haujlwm. Lub piston ncav cuag hauv qab ntawm daim cartridge tsuas yog thaum koj siv tag nrho 300 units uas muaj nyob hauv tus cwj mem syringe.

Tus cwj mem tsis tuaj yeem sib koom nrog lwm tus neeg, txawm tias thaum siv rab koob tshiab. Tsis txhob rov siv rab koob. Tsis txhob hla rab koob rau lwm tus neeg. Ib qho mob tuaj yeem sib kis tau nrog rab koob, uas tuaj yeem ua rau kis tau.

Yuav ua li cas QuickPen ™ syringe Cwj Pwm Sib Txawv:

Npaj cov ntawv xwj xim rau kev tswj hwm insulin:

• Ntxuav koj ob txhais tes nrog xab npum.
• Kuaj tshuaj hauv xaim hluav taws xob kom paub tseeb tias nws muaj hom insulin uas koj xav tau. Qhov no tseem ceeb heev yog tias koj siv ntau tshaj 1 hom tshuaj insulin.
• Tsis txhob siv cov xaum uas tas sij hawm raws li qhia ntawm daim ntawv lo.
• Txhua zaus yuav tsum tau siv cov koob tshiab nrog txhua txoj kev txhaj tshuaj tiv thaiv kev kis mob thiab tiv thaiv qhov txhaws ntawm koob.

Theem 2 (tsuas yog npaj rau Humalog Mix 25 thiab Humalog Mix 50):

• Maj mam muab cov kua xaum xaum nqus ntawm koj xib teg 10 npaug.
• Tig lub tshuaj txhuam dua 10 zaug.

Kev lo yog qhov tseem ceeb rau kev kuaj qhov tseeb. Cov tshuaj insulin yuav tsum saib zoo ib yam.

• Txheeb xyuas cov tshuaj insulin.

Humalog® yuav tsum pob tshab thiab xim tsis muaj xim. Tsis txhob siv yog tias nws yog huab, muaj qhov xim, lossis qee yam lossis txhaws.

Humalog® Mix 25 yuav tsum dawb thiab khov tom qab sib tov. Tsis txhob siv yog tias nws yog pob tshab, lossis yog tias muaj qee qhov txhaws lossis tawm muaj nyob hauv nws.

Humalog® Sib tov 50 yuav tsum yog xim dawb thiab huab tom qab sib tov. Tsis txhob siv yog tias nws yog pob tshab, lossis yog tias muaj qee qhov txhaws lossis tawm muaj nyob hauv nws.

Txheeb cov txhaj tshuaj xau rau txoj kev haus tshuaj

Xws li daim tshev yuav tsum tau nqa tawm ua ntej txhua txoj kev txhaj tshuaj.

• Kev kuaj xyuas cov kua xaum xaum rau kev haus tshuaj yog nqa tawm kom tshem tawm cov huab cua los ntawm rab koob thiab lub taub ntim, uas tuaj yeem ntxiv thaum lub sijhawm khaws cia ib txwm, thiab ua kom cov kua dej xaum ua haujlwm zoo.
• Yog tias koj tsis ua qhov kev kuaj ua ntej txhua qhov kev txhaj tshuaj, koj tuaj yeem nkag rau qhov qis dhau los lossis qis dhau ntawm qhov koob txhaj tshuaj insulin.

• Txuas ntxiv tuav tus tes tuav rab koob nrog rab koob kom txuas ntxiv. Nias lub khawm koob tshuaj kom txog thaum nws nres thiab "0" tshwm rau ntawm lub qhov ntsuas qhov ntsuas tshuaj. Thaum tuav lub koob tshuaj khawm, maj mam suav nrog 5.

Koj yuav tsum pom cov insulin ntawm qhov kawg ntawm rab koob.

Yog tias poob ntawm cov tshuaj insulin tsis tshwm sim rau ntawm lub ntsis ntawm rab koob, rov ua cov kauj ruam ntawm kev kuaj lub koob txhaj tshuaj rau kev siv tshuaj. Daim tshev tuaj yeem nqa tau tsis pub dhau 4 zaug.
- Yog tias qhov tshuaj insulin tseem tsis tshwm sim, hloov lub koob thiab rov ua daim tshev tshuaj ntsuam rau kev tswj hwm tshuaj.

Lub xub ntiag ntawm cov cua npuas me me yog qhov qub thiab tsis cuam tshuam rau qhov koob tshuaj tau muab.

Xaiv xaiv

• Koj tuaj yeem nkag los ntawm 1 txog 60 units ib zaug kev txhaj tshuaj.
• Yog tias koj cov tshuaj ntau dua 60 units. Koj yuav tsum tau ua ntau dua li kev txhaj tshuaj ib zaug.

Yog tias koj xav tau kev pab yuav faib cov koob tshuaj li cas, hu rau koj tus kws kho mob.
- Rau txhua txoj kev txhaj tshuaj, siv ib rab koob tshiab thiab rov ua qhov txheej txheem los kuaj xyuas lub koob txhaj tshuaj rau kev siv tshuaj.

• Tig lub pob tshuaj txhaj kom tau txais qhov koob tshuaj insulin uas koj xav tau. Qhov ntsuas qhov ntsuas yuav tsum nyob tib txoj kab nrog cov naj npawb ntawm qhov sib thooj rau koj cov koob tshuaj.

Nrog rau ib qho lem, lub pob tswj kev siv tshuaj hloov mus 1 chav nyob.
- Txhua zaus koj tig lub khawm koob tshuaj, ib qho nias tau tsim.
- Koj yuav tsum TSIS TXHOB xaiv ib koob tshuaj los ntawm kev suav nyem, vim tias cov koob tshuaj tsis yog yuav raug ntaus txoj hauv kev no.
- Lub koob tshuaj tuaj yeem hloov kho los ntawm tig khawm koob tshuaj nyob rau hauv qhov kev xav xav kom txog rau thaum ntawd. kom txog rau thaum ib daim duab sib thooj rau koj li kev tso tshuaj tshwm nyob rau hauv lub qhov taw qhia qhov tshuaj nyob ntawm kab ib kab nrog rau qhov ntsuas qhov ntsuas.
- Txawm hais tias cov lej raug qhia ntawm lub nplai.
- Cov lej khib, tom qab tus lej 1, qhia los ntawm cov kab khoom.

• Txhua zaus yuav tsum xyuas tus lej hauv lub ntsuas qhov ntsuas kom paub tseeb tias qhov tshuaj koj tau txhaj tshuaj puas raug.
• Yog tias muaj cov tshuaj insulin tsawg dua hauv cov xias syringe dua li qhov koj xav tau, koj siv tsis tau lub koob txhaj tshuaj kom tso cov tshuaj uas koj xav tau.
• Yog tias koj yuav tsum nkag mus rau hauv ntau qhov ntau dua li sab laug hauv lub taub ntim syringe. Koj tuaj yeem:

Ntaus qhov ntim uas tseem tshuav nyob hauv koj lub xias xias, thiab tom qab ntawd siv tus cwj mem tshiab los txhaj cov tshuaj seem, lossis
- noj tus cwj mem tshiab thiab nkag rau tag nrho cov tshuaj.

Kev Txhaj Tshuaj

• Txhaj tshuaj insulin raws nraim li koj tus kws kho mob tau qhia.
• Ntawm txhua qhov kev txhaj tshuaj, hloov pauv (hloov pauv) qhov chaw txhaj tshuaj.
• Tsis txhob sim hloov cov tshuaj thaum lub sijhawm txhaj tshuaj.

Cov tshuaj insulin yog txhaj rau hauv qhov tawv nqaij (sib luag) rau hauv lub xub ntiag ua ntej phab ntsa, pob tw, lub duav, lossis xub pwg.

• Ntxig lub koob tso rau hauv qab daim tawv nqaij.
• Nias lub koob tshuaj txuas ntxiv mus.

Tuav lub khawm koob tshuaj. suav maj mam mus txog 5, thiab tom qab ntawd tshem cov koob tawm ntawm daim tawv nqaij.

Tsis txhob sim muab cov tshuaj insulin los ntawm tig lub koob tshuaj. Thaum koj tig lub koob tshuaj khawm, cov tshuaj insulin tsis ntws.

• Tshem tawm rab koob ntawm daim tawv nqaij.
  "Qhov no tsis muaj dab tsi yog poob ntawm cov tshuaj insulin rau hauv lub taub hau." Qhov no tsis cuam tshuam qhov tseeb ntawm koj qhov kev noj tshuaj.
• Kos tus lej hauv lub ntsuas qhov rai.
  - Yog tias lub qhov rai ntsuas qhov ntsuas tshuaj yog "0", tom qab ntawd. Koj tau nkag siab qhov koob tshuaj koj tau noj tag nrho.
  - Yog tias koj tsis pom “0” rau hauv lub qhov ntsuas qhia tshuaj, tsis txhob rov ntaus dua. Ntxig lub koob tso rau hauv qab tawv nqaij dua thiab ua tiav kev txhaj tshuaj.
  - Yog tias koj tseem xav tias qhov tshuaj uas koj tau hu yuav tsis tau nkag rau hauv, tsis txhob rov ua qhov kev txhaj tshuaj. Kuaj koj cov piam thaj hauv ntshav thiab ua raws li koj tus kws kho mob qhia.
  - Yog tias koj yuav tsum tau txhaj 2 koob rau qhov tshuaj kom txhij, tsis txhob hnov ​​qab hno qhov koob thib ob.

Nrog txhua qhov kev txhaj tshuaj, lub piston tsuas yog txav me ntsis, thiab koj tuaj yeem tsis pom ib qho kev hloov pauv ntawm nws txoj haujlwm.

Yog tias koj pom tias muaj ntshav tawm tom qab tshem rab koob tawm ntawm daim tawv nqaij, ua tib zoo nias daim ntaub huv huv los yog cawv cawv rau qhov chaw txhaj tshuaj. Tsis txhob txhuam thaj chaw no.

Pov tseg ntawm koob txhaj tshuaj thiab koob

• Siv cov koob uas siv los tso rau hauv cov thawv ntim txag lossis lub thawv ntim khoom yas uas muaj lub hau kaw kom nruj. Tsis txhob muab rab koob tso rau hauv qhov chaw uas tau npaj tseg rau hauv tsev neeg pov tseg.
• Tus cwj mem uas siv siv tau tuaj yeem muab pov tseg nrog cov khoom pov tseg hauv tsev tom qab tshem tawm rab koob.
• Nrog koj tus kws kho mob tham txog yuav ua li cas koj lub ntim ntim rau ntawm cov ntse ntse.
• Cov lus qhia rau pov tseg cov koob nyob hauv phau ntawv no tsis hloov pauv cov cai, cov cai tswjfwm lossis cov cai tswjfwm siv los ntawm txhua lub tsev haujlwm.

Cwj mem cia

• Khaws cov xaum xaum tsis siv rau hauv lub tub yees ntawm qhov kub ntawm 2 ° C rau 8 ° C.
• Tsis txhob ua kom koj cov insulin. Yog tias nws khov lawm, tsis txhob siv nws.
• Cov pawm uas tsis siv lawm tuaj yeem khaws cia kom txog thaum hnub tas sij hawm uas tau sau rau ntawm daim ntawv lo, qhia tias lawv muab cia rau hauv tub yees.

Tus xaum qhuav siv tam sim no siv

• Khaws cov xaum xaum uas koj tab tom siv hauv chav sov txog 30 ° C hauv qhov chaw tiv thaiv los ntawm tshav kub thiab lub teeb.
• Thaum hnub tas sij hawm uas tau sau tseg rau ntawm pob ntawv tas sij hawm, cwj mem siv yuav tsum tau muab pov tseg, txawm hais tias insulin nyob hauv nws.

Kev daws teeb meem

• Yog tias koj tsis tuaj yeem tshem lub hau los ntawm tus xaum xaum, maj mam ntswj nws, thiab rub lub hau.
• Yog hais tias lub koob tshuaj khawm tau nias nyuaj:
  - Nias lub koob txhaj tshuaj khawm qeeb dua. Maj mam nias lub koob txhaj tshuaj khawm ua rau kev txhaj tshuaj yooj yim dua.
  "Tej zaum yuav txhaws tau." Ntxig rab koob tshiab thiab tshawb xyuas cov ntawv xaum xaum rau kev siv tshuaj.
  - Nws yog tau hais tias muaj plua plav lossis lwm yam khoom muaj nyob rau hauv xaum xaum xaum. Muab cov kua xaum xaum pov tseg thiab coj dua lub tshiab.

Yog tias koj muaj lus nug lossis teeb meem siv QuickPen Syringe Pen, tiv tauj Eli Lilly lossis koj tus kws kho mob.

Sawv cev nyob Xos Viav:

Eli Lilly Vostok S.A., 123112, Moscow
Presnenskaya embankment, d. 10

Lub teb chaws Fabkis zoo tshuaj insulin Humalog tau ua pov thawj nws zoo tshaj li analogues, uas yog ua tiav vim muaj kev sib txuam zoo ntawm cov kev ua haujlwm tseem ceeb thiab cov khoom pab txhawb nqa. Kev siv cov tshuaj insulin no ua kom yooj yim rau kev sib ntaus los tiv thaiv hyperglycemia hauv cov neeg mob kev mob ntshav qab zib.

Kev piav qhia ntawm Insulin Humalog

Luv insulin Humalog yog tsim los ntawm Fabkis lub tuam txhab Lilly Fabkis, thiab cov qauv qauv ntawm nws tso tawm yog qhov pom tseeb thiab tsis muaj kob, muab ntim rau hauv tshuaj ntsiav lossis lub taub hau. Lub tom kawg tuaj yeem muag tau raws li ib feem ntawm qhov tau npaj Txiag ceev syringe cwj mem, lossis cais rau tsib ampoules rau 3 ml hauv ib lub hlwv. Raws li lwm txoj hauv kev, Humalog Mix npaj ua tau tsim nyob rau hauv daim ntawv ntawm kev ncua rau kev tswj hwm subcutaneous, qhov ib txwm Humalog Mix tuaj yeem muab tshuaj nrog dej.

Lub hauv paus ua haujlwm tseem ceeb ntawm Humalog yog insulin lispro - ob-theem tshuaj ntawm qhov kub siab ntawm 100 IU rau 1 ml ntawm kev daws, qhov kev ua haujlwm uas tau tswj hwm los ntawm cov khoom siv hauv qab no ntxiv:

• glycerol
• metacresol
• zinc oxide
• sodium hydrogen phosphate heptahydrate,
• hydrochloric acid daws,
• Cov kua sodium hydroxide.

Los ntawm qhov pom ntawm cov pab pawg soj ntsuam thiab chaw muag tshuaj, Humalog yog hais txog cov yeeb yam ntawm cov neeg ua haujlwm insulin, tab sis txawv ntawm lawv hauv cov kab rov qab ntawm cov amino acids. Lub luag haujlwm tseem ceeb ntawm cov tshuaj yog tswj hwm kev nqus ntawm cov piam thaj, txawm hais tias nws tseem muaj cov yam ntxwv ntawm anabolic. Pharmacologically, nws ua raws li hauv qab no: hauv cov leeg nqaij, nce qib ntawm glycogen, fatty acids thiab glycerol yog kho, nrog rau kev nce ntxiv hauv cov concentration ntawm cov protein thiab kev noj cov amino acids los ntawm lub cev. Nyob rau hauv tib yam, cov txheej txheem xws li glycogenolysis, gluconeogenesis, lipolysis, protein catabolism, thiab ketogenesis qeeb.

Cov kev tshawb fawb pom tau tias hauv cov neeg mob uas muaj ob hom mob ntshav qab zib mellitus tom qab noj mov, cov ntshav qab zib nce tsawg dua sai dua yog tias Humalog siv es tsis txhob siv lwm cov tshuaj insulin.

Nws yog ib qho tseem ceeb kom nco ntsoov tias yog tias tus mob ntshav qab zib ib txhij tau txais cov tshuaj insulin luv luv thiab basal insulin, nws yuav tsim nyog kho qhov ntau npaum ntawm ob qho tshuaj thawj thiab thib ob kom tau txais txiaj ntsig zoo tshaj plaws. Dua li ntawm qhov tseeb tias Humalog yog cov insulins luv luv ua haujlwm, lub sijhawm kawg ntawm nws cov kev txiav txim siab raug txiav txim los ntawm ntau yam rau txhua tus neeg mob:

• tsuas tshuaj
• chaw txhaj tshuaj
• lub cev kub
• kev siv lub cev
• zoo ntawm cov ntshav txaus.

Nyias, nws yog tsim nyog sau cia qhov tseeb tias Humalog insulin zoo sib xws rau tib neeg cov ntshav qab zib thiab kho cov menyuam yaus lossis cov hluas. Nws tseem tsis hloov pauv tias cov nyhuv ntawm cov tshuaj tsis yog nyob ntawm qhov yuav tshwm sim ntawm lub raum lossis lub siab ua haujlwm hauv tus neeg mob, thiab thaum ua ke nrog cov koob tshuaj sulfonylurea ntau, cov qib ntawm glycated hemoglobin ho txo ​​qis. Feem ntau, tau muaj tus cim txo qis hauv cov neeg mob nocturnal hypoglycemia, los ntawm cov neeg mob ntshav qab zib feem ntau raug kev txom nyem yog tias lawv tsis noj cov tshuaj uas tsim nyog.

Cov yam ntxwv ntawm Humalog insulin qhia hauv cov lej zoo li qhov no: qhov pib ntawm kev nqis tes yog 15 feeb tom qab txhaj, lub sijhawm ua haujlwm yog los ntawm ob txog tsib teev. Ntawm ib sab tes, lub sijhawm ua haujlwm zoo ntawm cov tshuaj qis dua li ntawm cov tshuaj sib piv, thiab ntawm lwm qhov, nws tuaj yeem siv 15 feeb ua ntej noj mov, thiab tsis yog 30-35, zoo li lwm qhov insulins.

Kev qhia rau kev siv tshuaj

Insulin Humalog yog npaj rau txhua tus neeg mob uas mob hyperglycemia thiab xav tau kev kho mob insulin. Nws tuaj yeem yog ib lo lus nug ntawm ob hom 1 mob ntshav qab zib mellitus, uas yog cov kab mob tiv thaiv insulin, thiab hom ntshav qab zib hom 2, uas cov ntshav qab zib cov ntshav nce ntxiv tom qab ib pluas noj muaj carbohydrates.

Cov tshuaj insulin luv luv yuav ua tau zoo nyob rau txhua ntu ntawm tus kabmob, zoo rau cov neeg mob ntawm pojniam thiab pojniam txhua lub hnub nyoog. Raws li kev kho kom zoo, nws txoj kev sib xyaw ua ke nrog nruab nrab thiab ntev ua haujlwm insulins, pom zoo los ntawm tus kws kho mob tuaj koom, suav tias yog.

Cov lus qhia rau kev siv cov tshuaj insulin

Kev siv ntawm Humalog pib nrog kev suav qhov suav tshuaj, uas tau txiav txim siab los ntawm tus kws kho mob tau kawm, nyob ntawm tus mob ntshav qab zib xav tau cov tshuaj insulin. Cov tshuaj no tuaj yeem muab rau ob leeg ua ntej thiab tom qab noj mov, txawm hais tias thawj txoj kev xaiv zoo dua. Nco ntsoov nco ntsoov tias kev daws teeb meem yuav tsum tsis txhob txias, tab sis sib piv nrog chav sov. Feem ntau, ib qho qauv koob txhaj tshuaj, cwj mem, lossis insulin twj tso kua mis yog siv los tswj nws, txhaj tshuaj subcutaneously, txawm li cas los xij, nyob rau qee qhov xwm txheej, kev tso ntshav nkag tseem raug tso cai.

Kev txhaj tshuaj subcutaneous tau nqis tes yog ntawm tus ncej puab, lub xub pwg, lub plab lossis lub pob tw, qhov chaw hloov mus rau lwm qhov thiaj li siv tib qho tsis ntau tshaj ib hlis ib zaug. Kev saib xyuas yuav tsum tau ua kom tsis txhob nkag mus rau txoj leeg ntshav, thiab nws kuj tseem yuav tsum nruj me ntsis kom tsis txhob zaws tawv nqaij hauv qhov chaw txhaj tshuaj tom qab nws tau ua. Lub humalog muas hauv daim ntawv ntawm tus cartridge rau daim ntawv xaum yog siv hauv qhov kev txiav txim hauv qab no:

1. koj yuav tsum ntxuav koj ob txhais tes nrog dej sov thiab xaiv qhov chaw rau kev txhaj tshuaj,
2. cov tawv nqaij hauv thaj chaw txhaj tshuaj yog tshuaj tua kab mob nrog cov tshuaj tua kab mob,
3. qhov kev tiv thaiv tau muab tshem tawm los ntawm rab koob,
4. daim tawv nqaij yog tsau manually los ntawm rub los yog rub tawm kom cov quav tau,
5. ib rab koob tau ntxig rau hauv daim tawv nqaij, lub pob nyem rau ntawm rab koob xaum yog nias,
6. lub koob raug tshem tawm, qhov chaw txhaj tshuaj yog maj mam nias rau ob peb feeb (tsis tas yuav zaws thiab txhuam),
7. nrog kev pab ntawm lub hau tiv thaiv, lub koob tau muab tso tseg thiab tshem tawm.

Tag nrho cov kev cai no siv rau cov hom tshuaj no zoo li Humalog Mix 25 thiab Humalog Mix 50, tsim nyob rau hauv daim ntawv ntawm ncua kev kawm. Qhov sib txawv nyob rau hauv qhov pom thiab npaj rau ntau hom tshuaj: kev daws teeb meem yuav tsum tsis muaj xim thiab pob tshab, thaum nws tam sim ntawd npaj rau kev siv, thaum lub sijhawm muab ncua yuav tsum tau co ob peb zaug kom lub cartridge muaj qhov tsis sib xws, kua huab, zoo ib yam li mis.

Kev siv tshuaj tiv thaiv ntawm Humalog yog nqa tawm hauv qhov chaw kho mob uas siv tus txheej txheem infusion uas qhov kev daws teeb meem yog tov nrog 0.9% sodium chloride tov lossis 5% dextrose daws. Kev siv cov tshuaj insulin twj rau kev qhia ntawm Humalog yog txhim tsa raws li cov lus qhia uas txuas rau ntawm lub cuab yeej. Thaum nqa tawm kev txhaj tshuaj ntawm ib yam twg, koj yuav tsum nco ntsoov cov piam thaj 1 ntau ntawm cov insulin txo cov piam thaj kom thiaj li ntsuas tau qhov koob tshuaj thiab tshuaj tiv thaiv ntawm lub cev. Qhov nruab nrab, qhov ntsuas no yog 2.0 mmol / L rau kev npaj tshuaj insulin feem ntau, uas kuj muaj tseeb rau Humalog.

Kev cuam tshuam nrog lwm yam tshuaj

Qhov sib cuam tshuam yeeb tshuaj ntawm Humalog nrog lwm cov tshuaj nyob rau hauv sib haum rau nws cov analogues. Yog li, qhov ua kom lub ntsej muag hypoglycemic yuav txo qis thaum nws tau ua ke nrog kev tiv thaiv qhov ncauj, glucocorticosteroids, cov tshuaj hormones rau cov thyroid caj pas, tus lej ntawm diuretics thiab tshuaj tiv thaiv kab mob, nrog rau nicotinic acid.

Tib lub sijhawm, cov nyhuv ntshav hypoglycemic ntawm insulin yuav ua rau muaj zog nrog kev siv tshuaj los ntawm kev siv:

• beta blockers,
• ethanol thiab tshuaj raws li nws,
• anabolic tshuaj yuam
• cov tshuaj hypoglycemic qhov ncauj,
• sulfonamides.

Cov lus thiab cov xwm txheej ntawm kev cia

Cov xov tooj ntawm tes yuav tsum muab tso rau hauv qhov chaw uas cov me nyuam nkag tsis tau rau hauv lub tub yees zoo, ntawm qhov kub ntawm +2 txog +8 degrees Celsius. Cov txheej txheem txee lub neej yog ob xyoos. Yog tias cov pob twb tau qhib lawm, cov tshuaj insulin no yuav tsum ceev cia hauv chav sov li ntawm +15 txog +25 degrees Celsius.

Kev saib xyuas yuav tsum tau ua kom ntseeg tau tias cov tshuaj tsis ua kom sov thiab tsis nyob rau hauv tshav ntuj. Thaum pib siv, lub txee lub neej txo mus rau 28 hnub.

Cov tshuaj tiv thaiv ncaj qha ntawm Humalog yuav tsum xav txog tag nrho cov tshuaj insulin npaj rau cov ntshav qab zib hauv txoj kev zoo sib xws.Ntawm cov nto moo tshaj plaws yog Actrapid, Vosulin, Gensulin, Insugen, Insular, Humodar, Isofan, Protafan thiab Homolong.