Cov tshuaj tiv thaiv hypoxlycemic Maninil thiab nws cov tshuaj yeeb yam

Ntxiv rau, nws suppresses hepatic gluconeogenesis thiab glycogenolysis, inhibits lipolysis qabzib, thiab txo cov ntshav thrombogenicity. Lub sijhawm tiv thaiv ntawm cov ntshav hypoglycemic uas ua los ntawm cov tshuaj 2 teev tom qab kev tswj hwm yog txog 12 teev.

Ntsiav tshuaj Glibenclamide Maninyl 3.5 mg

Kev ua kom muaj qab zib-txo cov khoom sib xyaw ntawm Maninil - glibenclamide, nthuav tawm hauv micronized daim ntawv, muaj cov nyhuv ntxim nyiam ntawm lub cev, sai sai nqus ntawm lub plab los ntawm 48-84%. Tom qab noj cov tshuaj, tag nrho kev tso tawm ntawm glibenclamide tshwm sim hauv 5 feeb. Tus nquag ua tiav rau hauv lub siab thiab tawm ntawm lub raum thiab bile.

Cov tshuaj yog tsim hauv cov ntsiav tshuaj nrog ntau qhov sib txawv ntawm cov tshuaj nquag 1 ntsiav tshuaj:

Cov ntsiav tshuaj yog tiaj-cylindrical nyob rau hauv cov duab, nrog chamfer thiab ib lub cim thov rau ib qho ntawm cov chaw, xim yog xim liab.

Cov chaw tsim kev lag luam ntawm cov tshuaj yog FC Berlin-Chemie; hauv cov chaw muag tshuaj nws tau faib tshwj xeeb los ntawm cov tshuaj noj. Cov tshuaj ntim rau hauv cov hwj ntawm cov iav pob tshab, 120 pcs txhua qhov. hauv txhua, lub fwj lawv tus kheej ntxiv tau ntim rau hauv cov thawv ntawv thawv. Cov ntawv qhia Latin rau Maninil yog raws li nram no: Maninil.

Raws li kev tshawb fawb, ua raws li qhov tsim nyog noj tshuaj thaum noj cov tshuaj kom paub meej txo qis kev pheej hmoo ntawm kev mob plawv thiab lwm yam teeb meem cuam tshuam los ntawm cov ntshav qab zib tsis muaj insulin, suav nrog kev tuag ntawm cov kab mob no.

Analogs hauv kev muaj pes tsawg leeg thiab qhia txog kev siv

Cov npe saum toj no ntawm cov yeeb tshuaj analogues, uas qhia Maninil hloov chaw, yog qhov tsim nyog tshaj plaws vim tias lawv muaj tib cov tshuaj sib luag thiab sib luag ua ke raws li kev taw qhia rau kev siv

Analogs los ntawm qhov taw qhia thiab cov qauv ntawm kev siv

Sib txawv muaj pes tsawg leeg, tuaj yeem ua ke nyob rau hauv kev taw qhia thiab cov qauv ntawm daim ntawv thov

Yuav ua li cas thiaj nrhiav tau qhov pheej yig tshuaj ntawm cov tshuaj kim?

Txhawm rau kom pom qhov pheej yig cov khoom sib piv rau cov tshuaj, cov dav dav lossis cov lus sau, ua ntej txhua yam peb pom zoo kom them sai sai rau qhov muaj pes tsawg leeg, uas yog rau tib cov tshuaj nquag thiab qhia tau rau kev siv. Cov tshuaj sib xyaw zoo ib yam ntawm cov tshuaj yuav qhia tau tias cov tshuaj cuam tshuam nrog cov tshuaj, kws tshuaj sib npaug lossis chaw muag tshuaj. Txawm li cas los xij, tsis txhob hnov ​​qab txog qhov ua tsis muaj zog ntawm cov tshuaj uas zoo sib xws, uas tuaj yeem cuam tshuam kev nyab xeeb thiab ua haujlwm. Tsis txhob hnov ​​qab txog cov lus qhia ntawm cov kws kho mob, kev noj tshuaj rau nws tus kheej tuaj yeem tsim kev puas tsuaj rau koj kev noj qab haus huv, yog li nco ntsoov sab laj nrog koj tus kws kho mob ua ntej siv cov tshuaj.

Kev ntsuas rau siv

Manilin kev tswj hwm tau taw qhia rau kev ntsuas kab mob-insulin-ywj pheej ntawm cov ntshav qab zib mellitus (ntawm yam thib ob). Nws tuaj yeem raug tshuaj raws li kev noj ib leeg lossis ua ke nrog lwm cov tshuaj hypoglycemic. Ib qho kev zam yog qhov kev tswj hwm koom tes nrog glinides thiab sulfonylurea derivatives.

Cov yam ntxwv ntawm qhov ntau npaum thiab kev tswj hwm

Kev noj tshuaj ntawm Maninil yog pom zoo ua ntej noj mov, ntxuav thiab tsis yog zom.

Kev noj tshuaj txhua hnub yog txiav txim los ntawm kev tsom kwm tus kws tshuaj endocrinologist ib tus zuj zus:

1. yog tias nws tsis pub tshaj 2 ntsiav tshuaj ib hnub, tom qab ntawd cov tshuaj yuav tsum noj ib zaug, zoo dua thaum sawv ntxov - ua ntej noj tshais,
2. thaum sau daim ntawv noj tshuaj kom ntau dua, kev siv tshuaj kho mob yog coj tawm 2 zaug - thaum sawv ntxov - ua ntej noj tshais thiab yav tsaus ntuj - ua ntej noj hmo.

Kev txiav txim siab los xaiv tus txheej txheem kho mob yog pes tsawg lub xyoo, qhov mob hnyav, thiab cov ntsiab lus ntawm cov piam thaj hauv cov ntshav ntawm lub plab khoob thiab tom qab noj mov 2 teev.

Thaum tsis tshua muaj txiaj ntsig ntawm kev siv tshuaj ntau los ntawm kws kho mob, kev txiav txim siab tuaj yeem ua kom nws nce ntxiv. Cov txheej txheem ntawm kev nce qhov ntau ntxiv rau qib siab zoo tshaj plaws yog nqa tawm maj - txij li 2 txog 7 hnub, ib txwm nyob hauv kev saib xyuas ntawm kws kho mob.

Nyob rau hauv cov ntaub ntawv ntawm hloov mus rau Maninil los ntawm lwm qhov kev npaj tshuaj uas muaj cov nyhuv hypoglycemic, nws txoj kev tswj hwm tau raug tshaj tawm nyob rau hauv tus qauv pib ntau npaum li cas, yog tias tsim nyog, nce, nws tau ua tiav thiab yam tshwj xeeb hauv kev saib xyuas mob.

Txheem Pib Dosage ntawm Maninil:

• muaj 1.75 mg ntawm cov khoom xyaw dhia - yog tau 1-2 ntsiav tshuaj ib hnub ib zaug. Qhov siab tshaj plaws yuav tsum tsis pub tshaj 6 ntsiav tshuaj hauv ib hnub,
• muaj 3.5 mg ntawm cov tshuaj nquag - 1 / 2-1 ntsiav tshuaj ib hnub ib zaug. Qhov siab tshaj plaws yog 3 ntsiav tshuaj hauv ib hnub,
• muaj 5 mg ntawm cov tshuaj ua kom nquag plias - yog ½-1 ntsiav tshuaj 1 zaug nyob rau ib hnub. Qhov siab tshaj plaws tau txais kev noj tshuaj rau txhua hnub yog 3 ntsiav tshuaj.

Cov neeg laus (laus dua 70 xyoo), cov uas ua raws li txoj kev noj zaub mov zoo, nrog rau cov neeg uas lub raum lossis lub siab ua haujlwm tsis zoo, nws raug nquahu kom siv cov tshuaj txo qis vim qhov kev hem thawj ntawm hypoglycemia.

Yog tias koj tsis nco qab noj ib qho tshuaj, qhov tshuaj txuas ntxiv ntawm Maninil tau tsim hauv cov txheej txheem ntau npaum li cas (tsis muaj nce ntxiv) thaum lub sijhawm tsis tu ncua.

Sab sij huam

Ntshav qab zib yog ntshai ntawm cov tshuaj no, zoo li hluav taws!

Koj tsuas yog xav tau thov ...

Cov tsos ntawm kev tsis sib haum xeeb hauv kev ua haujlwm ntawm qee qhov system thaum noj Maninil yog qhov tsis tshua pom. Lawv qhov tshwm sim tsis tshua muaj neeg tuaj yeem ua tau:

• los ntawm lub plab zom mov - nyob rau hauv daim ntawv ntawm xeev siab, ntuav, ib qho kev xav ntawm lub nra hnyav hauv plab, qhov zoo li xim hlau tsis pom hauv lub qhov ncauj, raws plab,
• los ntawm lub siab - nyob rau hauv daim ntawv ntawm kev ua haujlwm ib ntus ntawm daim siab enzymes, kev txhim kho ntawm mob chraestatic cholestasis lossis kab mob siab,
• los ntawm sab ntawm metabolism - nyob rau hauv daim ntawv ntawm qhov hnyav nce los yog lub cev qog ntshav nrog nws cov yam ntxwv tshwm sim - tshee, nce tawm hws, pw tsaug zog ntxhov siab, ntxhov siab, mob taub hau, tsis pom kev lossis hais lus,
• nyob rau ib feem ntawm kev tiv thaiv kab mob - nyob rau hauv daim ntawv ntawm ntau yam kev tsis haum rau daim tawv nqaij - petechiae, khaus, hyperthermia, photosensitivity thiab lwm tus,
• los ntawm hom kab mob hematopoietic - nyob rau hauv daim ntawv ntawm thrombocytopenia, hemolytic anemia, erythrocytopenia,
• ntawm feem ntawm cov khoom siv pom - Txoj hauv kev ua txhaum txoj kev pab.

Lub ntsiab lus tseem ceeb thaum noj Maninil yog nruj ua raws li cov lus qhia kho mob hais txog kev noj zaub mov noj thiab ntshav qabzib nws tus kheej kev soj ntsuam. Thaum tus neeg mob dhau lawm, lub qog ua kom ntshav nce siab yuav tshwm sim nrog cov yam ntxwv ua pov thawj.

Yog tias pom cov tsos mob me me ntawm kev noj ntau dhau, nws pom zoo kom noj qab zib me ntsis lossis zaub mov nplua nuj hauv kev zom cov zaub mov muaj kuab kom yooj yim. Txog ntawm cov foos hnyav heev ntawm kev txhaj tshuaj ntau dhau, iv txhaj tshuaj qabzib tov yog kho tau. Hloov ntshav qabzib, IM lossis txhaj tshuaj ntawm glucagon tau siv tau.

Txoj kev pheej hmoo ntawm hypoglycemia nce yog tias:

• haus cawv kom tsawg
• carbohydrate tsis txaus
• ntev so nruab nrab ntawm pluas noj,
• ntuav lossis kem plab,
• kev tawm dag zog lub cev.

Cov cim qhia ntawm cov ntshav qog ntshav yuav tuaj yeem npog thaum noj Maninil nrog cov tshuaj uas cuam tshuam rau hauv cov hlab ntsha hauv nruab nrab lossis tuaj yeem txo ntshav siab.

Cov nyhuv ntawm Maninil tej zaum yuav raug txo kom tsawg dua thaum nws siv nrog barbiturates, kev tswj tsis pub lwm tus thiab lwm yam tshuaj uas muaj cov tshuaj hormones. Thiab ntawm qhov tsis sib xws, siv cov tshuaj tiv thaiv ib leeg, reserpine, tetracyclines, anabolic steroids muaj peev xwm txhim kho nws qhov kev txiav txim.

Cov Kev Txwv thiab contraindications

Thaum kho nrog Maninil, nws raug nquahu kom tsis txhob muaj lub hnub ntev, nrog rau kev ua kom ceev faj thaum tsav tsheb, ua haujlwm rau lwm tus uas xav tau kev saib xyuas, xav tau, nrog rau kev ua haujlwm sai.

Ib cov tshuaj hypoglycemic yog contraindicated nyob rau hauv qhov kev tshwm sim ntawm muaj:

• mob ntshav qab zib-insulin
• daim siab ua hauj lwm
• hnyuv ob tog,
• mob ketoacidosis,
• mob ntshav qab zib coma lossis precoma,
• paresis ntawm lub plab
• leukopenia
• lactose intolerance thiab tsis muaj lactase,
• muaj kev cuam tshuam ntau ntxiv rau cov tshuaj tiv thaiv nquag - glibenclamide lossis lwm yam tshwm sim hauv cov tshuaj,
• muaj lub cev tsis haum rau PSM, nrog rau sulfonamides thiab cov tshuaj diuretics uas muaj cov khoom qub ntawm sulfonamide pawg,
• tshem tawm ntawm lub pancreas.

Kev tshem tawm ntawm Maninil thiab nws qhov hloov pauv nrog cov kua dej yog ua yog tias:

• mob ailments nrog febrile tshwm,
• tus txheej txheem ntxeem tau
• nws kim heev,
• kev raug mob
• cev xeeb tub lossis xav tau kev pub niam mis.

Nrog kev ceev faj, cov tshuaj no yuav tsum tau noj nyob rau hauv muaj kev ua tsis tiav ntawm cov thyroid caj pas, adrenal cortex, mob hnyav ua mob los ntawm haus dej cawv.

Ib cov tshuaj hypoglycemic yog contraindicated rau hauv cov menyuam yaus.

Yuav ua li cas los hloov Maninil: analogues thiab tus nqi

Zoo li feem ntau cov tshuaj, Maninil muaj cov lus txhais thiab analogues. Ib qho kev coj ua zoo sib xws muaj ib tug xov tooj ntawm cov tshuaj txo cov ntshav qab zib, cov nquag ua haujlwm ntawm cov tshuaj glibenclamide.

Maninyl 3,5 analogues muaj cov hauv qab no:

• Glibomet - los ntawm 339 rubles,
• Glibenclamide - los ntawm 46 rubles,
• Maninil 5 - los ntawm 125 rubles.

Cov neeg mob mob siab rau cov analogues muaj ib tug lej ntawm cov lus nug, piv txwv li, nws yog ib qho zoo dua - Maninil lossis Glibenclamide? Hauv qhov no, txhua yam yog yooj yim. Glibenclamide yog Maninil. Tsuas yog tus thib ob yog lub high-tech tshwj xeeb milled daim ntawv ntawm thawj.

Thiab qhov twg yog qhov zoo dua - Maninil lossis Glidiab? Hauv qhov no, tsis muaj cov lus teb tshwj xeeb, txij li ntau tau nyob ntawm tus neeg yam ntxwv ntawm tus neeg mob.

Analogues ntawm Maninil rau hom ntshav qab zib hom 2 los ntawm kev ua kom zoo:

• Amaril - los ntawm 350 rubles,
• Vazoton - los ntawm 246 rubles,
• Arfazetin - los ntawm 55 rubles,
• Glucophage - los ntawm 127 rubles,
• Listata - los ntawm 860 rubles,
• Tus mob ntshav qab zib - los ntawm 278 rubles,
• Xenical - los ntawm 800 rubles,
• thiab lwm tus.

Xaiv cov tshuaj analogue ntawm Maninil, cov kws tshaj lij pom zoo muab kev nyiam rau cov tshuaj uas tsim los ntawm Japanese, Asmeskas thiab Western European cov tuam txhab lag luam: Gideon Richter, Krka, Zentiv, Hexal thiab lwm yam.

Kev qhia Maninil

LUS QHIA
ntawm kev siv cov tshuaj
Maninil

Daim ntawv tso tawm
Ntsiav tshuaj

Muaj pes tsawg leeg
1 ntsiav tshuaj muaj:
Cov tshuaj yeeb tshuaj: glibenclamide (hauv micronized form) 1.75 mg.
Cov muaj mob: cov lactose monohydrate, cov hmoov txhuv nplej siab, gimetellosa, colloidal silicon dioxide, magnesium stearate, zas xim liab (Ponceau 4R) (E124)

Ntim
nyob rau hauv lub khob ntim ntawm 120 pcs., hauv ib pob ntawm cardboard ntawm 30 lossis 60 pcs.

Pharmacological kev txiav txim
Cov Tshuaj Hauv Tshuaj
Kev siv tshuaj yaj yeeb hypoglycemic los ntawm pawg sulfonylurea derivatives ntawm lub cim thib ob.
Nws stimulates insulin secretion los ntawm khi rau pancreatic cell-cell membrane tshwj xeeb receptors, txo qhov pib rau pancreatic cell-cell kua nplaum voos, nce insulin rhiab heev thiab nws khi rau lub hom phiaj hlwb, nce insulin tso tawm, ua rau muaj kev cuam tshuam ntawm insulin ntawm cov leeg qabzib nce siab thiab mob siab, yog li txo qhov kev txiav txim siab ntawm cov piam thaj hauv cov ntshav. Kev ua nyob rau theem ob ntawm insulin secretion. Nws inhibits lipolysis nyob rau hauv cov ntaub so ntswg adipose. Nws muaj lipid-txo cov nyhuv, txo qhov ua kom lub zog thrombogenic ntawm cov ntshav.
Maninil® 1.5 thiab Maninil® 3.5 hauv micronized daim ntawv yog lub siab, tshwj xeeb tshaj yog hauv av daim ntawv ntawm glibenclamide, uas tso cai rau cov tshuaj kom nqus ntawm cov hnyuv sai dua. Hauv kev sib txuas nrog kev ua tiav dhau los ntawm Cmax ntawm glibenclamide hauv ntshav, cov nyhuv hypoglycemic yuav luag raug rau lub sijhawm nce ntxiv hauv kev mloog zoo ntawm cov piam thaj hauv cov ntshav tom qab noj mov, uas ua rau cov nyhuv ntawm cov tshuaj softer thiab physiological. Lub sijhawm ntawm hypoglycemic kev ua yog 20-24 teev.
Qhov ua rau lub ntsej muag hypoglycemic ntawm cov tshuaj Maninil® 5 kev txhim kho tom qab 2 teev thiab kav ntev li 12 teev.

Cov Tshuaj Pharmacokinetics
Xuas
Tom qab noj cov tshuaj Maninil 1.75 thiab Maninil 3.5, kev nqus sai thiab yuav luag tiav los ntawm kev kho mob txoj hnyuv. Tso tawm tag nrho ntawm cov tshuaj microionized nquag tshwm sim hauv 5 feeb.
Tom qab kev noj cov tshuaj ntawm Maninil 5, nqus ntawm lub plab zom mov yog 48-84%. Tmax - 1-2 teev. Teev tsis raug bioavailability - 49-59%.
Kev xa Khoom
Plasma protein khi yog ntau tshaj li 98% rau Maninil 1.75 thiab Maninil 3.5, 95% rau Maninil 5.
Kev ntsuas phoo thiab nthuav tawm
Yuav luag txhua qhov ua tiav nyob hauv daim siab nrog rau kev tsim ntawm ob lub cev tsis ua haujlwm, ib qho yog tawm los ntawm lub raum, thiab lwm qhov yog cov kua tsib.
T1 / 2 rau Maninil 1.75 thiab Maninil 3.5 yog 1.5-3.5 teev, rau Maninil 5 - 3-16 teev.

Maninil, kev taw qhia rau kev siv
Hom 2 mob ntshav qab zib mellitus (non-insulin-dependant) nrog qhov tsis muaj txiaj ntsig ntawm kev noj zaub mov noj, yuag poob nrog kev rog thiab lub cev txaus.

Cov Yuav Tsum Tau Ua
Hypersensitivity (suav nrog rau cov tshuaj sulfonamide thiab lwm yam sulfonylurea derivatives), hom 1 mob ntshav qab zib mellitus (insulin-dependant), tshuaj tiv thaiv metabolic decompensation (ketoacidosis, precoma, coma), pancreatic resection, mob ntshav siab thiab mob raum, qee yam mob hnyav (piv txwv li, decompensation ntawm carbohydrate metabolism hauv cov kab mob sib kis, hlawv kub hnyiab, raug mob lossis tom qab phais mob loj thaum siv tshuaj tua kab mob insulin), mob leukopenia, mob plab hnyuv, paresis ntawm lub plab, tej yam kev mob uas cuam tshuam nrog malabsorption ntawm cov zaub mov thiab kev txhim kho hypoglycemia, cev xeeb tub thiab lub sijhawm pub mis.

Tsuas tshuaj thiab tswj hwm
Maninyl 1.75 noj ntawm qhov ncauj, thaum sawv ntxov thiab yav tsaus ntuj, ua ntej noj mov, yam tsis txham. Cov koob tshuaj tau teeb tsa ib leeg zuj zus, nyob ntawm qhov mob hnyav ntawm tus kab mob.
Thawj qhov tshuaj yog 1/2 ntsiav tshuaj, qhov nruab nrab yog 2 ntsiav tshuaj. tauj ib hnub, qhov ntau - 3, tshwj tsis yog - 4 ntsiav tshuaj. ib hnub. Yog tias nws tsim nyog yuav tsum tau txhaj tshuaj ntau dua (txog 14 mg / hnub), lawv hloov mus rau 3.5 mg maninil.

Cev xeeb tub thiab lactation
Cov tshuaj yog contraindicated rau kev siv thaum cev xeeb tub thiab thaum pub mis.
Thaum cev xeeb tub tshwm sim, cov tshuaj yuav tsum tau tsum tsis ua ntxiv.

Sab sij huam
Kev mob ntshav qab zib yog ua tau (nrog cov zaub mov noj qab haus huv, noj tshuaj ntau dhau, nrog rau lub cev ua kom lub cev ntau ntxiv, nrog rau kev haus dej cawv ntau).
Los ntawm cov hnyuv hauv plab: qee zaus - xeev siab, ntuav, qee kis - mob cholestatic daj ntseg, kab mob siab.
Los ntawm cov kab mob hemopoietic: tsis tshua muaj mob - thrombocytopenia, granulocytopenia, erythrocytopenia (txog pancytopenia), qee kis - mob ntshav khov hemolytic.
Ua xua: tsis tshua muaj tshwm sim - xoo pob khaus, ua npaws, mob sib koom tes, proteinuria.
Lwm yam: thaum pib ntawm kev kho mob, kev hloov chaw nyob qhov tsis yooj yim yog qhov ua tau. Nyob rau hauv tsawg zaus, photosensitivity.

Cov lus qhia tshwj xeeb
Thaum lub sijhawm kho nrog Maninil it, nws yog ib qho tsim nyog yuav tsum ua raws li kws kho mob pom zoo txog kev noj zaub mov noj thiab tshuaj xyuas tus kheej ntawm cov ntshav qab zib.
Kev tsis yoo ncua sij hawm ntau los ntawm kev noj zaub mov, cov zaub mov tsis txaus rau lub cev, kev qoj ib ce lub cev, zawv plab lossis ntuav ua rau muaj kev pheej hmoo ntawm cov ntshav qab zib.
Kev siv cov tshuaj ib txhij nrog cov ua haujlwm hauv lub hauv nruab nrab lub paj hlwb, txo cov ntshav siab (suav nrog beta-blockers), ntxiv rau peripheral neuropathy, tuaj yeem npog cov tsos mob ntawm kev mob ntshav qab zib.
Hauv cov neeg laus cov neeg mob, txoj kev pheej hmoo ntawm kev mob hypoglycemia yog siab dua me ntsis, yog li, kev xaiv ntau dua ntawm cov tshuaj ntawm cov tshuaj thiab kev soj ntsuam tsis tu ncua ntawm cov concentration ntawm cov piam thaj hauv cov ntshav ntawm lub plab khoob thiab tom qab noj mov, tshwj xeeb tshaj yog thaum pib kho, tsim nyog.
Cov dej cawv yuav ua rau qhov kev txhim kho ntawm cov ntshav qab zib, nrog rau kev txhim kho ntawm disulfiram zoo li cov tshuaj tiv thaiv (xeev siab, ntuav, mob plab, hnov ​​qhov kub ntawm lub ntsej muag thiab lub cev sab saud, tachycardia, kiv taub hau, mob taub hau), yog li koj yuav tsum tsis txhob haus cawv thaum kho mob nrog Maninil®.
Kev phais mob thiab kev raug mob loj, kev kub nyhiab, kab mob kis nrog febrile syndrome yuav tsum tsis siv tshuaj txuas ntxiv hauv qhov ncauj thiab ua cov tshuaj insulin.
Thaum kho, kev tiv thaiv ntev ntev tiv tshav ntuj tsis pom zoo.

Cuam tshuam rau kev muaj peev xwm tsav tsheb thiab lwm cov txheej txheem xav tau nce siab mloog
Thaum kho, cov neeg mob yuav tsum tau ceev faj thaum tsav tsheb thiab lwm yam kev phom sij uas yuav tsum muaj kev saib xyuas ntau dua thiab nrawm rau cov kev puas siab puas ntsws.

Yeeb tshuaj sib cuam tshuam
Txhim kho cov tshuaj hypoglycemic ntawm Maninil® muaj peev xwm ua tau thaum noj ACE inhibitors, anabolic tus neeg sawv cev thiab txiv neej pw ua ke, lwm yam kab mob hypoglycemic qhov ncauj (piv txwv li, acarbose, biguanides) thiab insulin, azapropazone, NSAIDs, beta-adrenergic block agents, chlorofibrinol derivatives, chinofenolone nws cov analogues, coumarin derivatives, disopyramide, fenfluramine, tshuaj tua kab mob (miconazole, fluconazole), fluoxetine, MAO inhibitors, PA SC, pentoxifylline (hauv kev txhaj tshuaj ntau rau kev tswj hwm kev tswj hwm), perhexylin, pyrazolone derivatives, phosphamides (e.g. cyclophosphamide, ifosfamide, trophosphamide), probenecid, salicylates, sulfonamides, tetracyclines thiab tritoqualin.
Cov neeg tso zis acidifying agents (ammonium chloride, calcium chloride) txhim kho cov nyhuv ntawm cov tshuaj Maninil® los ntawm kev txo qis hauv nws cov neeg ua haujlwm tsis zoo thiab ua kom nws txoj kev rov cuam tshuam dua.
Cov nyhuv hypoglycemic ntawm Maninil® yuav txo qis nrog kev siv barbiturates tib lub sijhawm, isoniazid, diazoxide, GCS, glucagon, nicotinates (hauv kev txhaj tshuaj ntau), phenytoin, phenothiazines, rifampicin, thiazide diuretics, acetazolamide, tshuaj tiv thaiv qhov ncauj thiab estrogen cov tshuaj, estrogen cov tshuaj hormones, thiab estrogen. , cov khoom thaiv ntawm qeeb calcium calcium, lithium ntsev.
H2 receptor antagonists tuaj yeem ua kom tsis muaj zog, ntawm ib sab tes, thiab txhim kho cov nyhuv hypoglycemic ntawm Maninil® ntawm lwm qhov.
Muaj qee zaus, pentamidine tuaj yeem ua rau muaj zog txo lossis nce ntxiv hauv cov ntshav cov piam thaj.
Nrog rau kev siv thooj txhij nrog cov tshuaj Maninil®, cov txiaj ntsig ntawm coumarin derivatives yuav nce ntxiv los yog tsawg dua.
Nrog rau kev nce siab ntawm hypoglycemic, beta-blockers, clonidine, guanethidine thiab reserpine, ntxiv rau cov tshuaj nrog qhov ua haujlwm nruab nrab ntawm kev txiav txim siab, tuaj yeem ua rau tsis muaj zog ntawm cov tsos mob ntawm hypoglycemia.

Noj ntau dhau
Cov tsos mob: hypoglycemia (kev tshaib kev nqhis, hyperthermia, tachycardia, qaug zog, qaug zog, ya raws ntawm daim tawv nqaij, ua kom tsis muaj kev sib koom tes ntawm kev txav, kev tshee, kev ntxhov siab, ntshai, mob taub hau, mob puas hlwb, tsis hloov mus los (piv txwv, pom thiab hais lus tsis meej, paresis lossis tuag tes tuag taw lossis hloov txoj kev xav ntawm kev hnov.) Nrog kev nce qib ntawm kev mob ntshav qab zib, cov neeg mob yuav plam lawv tus kheej kev tswj hwm thiab kev nco qab, qhov kev txhim kho ntawm hypoglycemic coma.
Kev Kho Mob: Yog tias qhov mob ntshav qab zib tsawg, tus neeg mob yuav tsum nqa ib qho qab zib, zaub mov lossis dej qab zib nrog cov piam thaj hauv siab (jam, zib ntab, ib khob dej qab zib) hauv. Yog tias tsis nco qab, nws yog ib qhov tsim nyog yuav tau txhaj iv qabzib - 40-80 ml ntawm 40% dextrose tov (qabzib), tom qab ntawd ua li ntawm 5-10% dextrose tov. Tom qab ntawd koj tuaj yeem txuas ntxiv rau 1 mg ntawm glucagon hauv / hauv, / m lossis s / c. Yog tias tus neeg mob tsis rov qab nco qab, ces qhov kev ntsuas no tuaj yeem rov qab ua dua; ntxiv mus, yuav tsum muaj kev kho mob hnyav ntxiv.

Cia rau cov neeg mob
Khaws rau hauv qhov chaw tsaus ntawm qhov kub tsis tshaj 25 ° C.

Hnub tas sij hawm
3 xyoos