Ciprolet 500 tshuaj: kev taw qhia, phiv thiab contraindications

Cov tshuaj "Tsiprolet 500" yog hais txog cov tshuaj tua kab mob thiab muaj nyob hauv pawg ntawm fluoroquinolones. Nws yog rau kev kho mob kis mob pathologies uas ua rau microflora nkag siab cov tshuaj. Lub cuab yeej muaj cov haujlwm siab thiab nrawm.

Kev kho mob nyhuv ntawm cov tshuaj "Tsiprolet 500"

Cov tshuaj cuam tshuam nrog kev luam tawm ntawm cov kab mob DNA, yog li ua txhaum lawv faib thiab kev loj hlob. Cov tshuaj yog siv tshwj xeeb rau kev kho mob rau cov kab mob uas ua rau muaj cov kab mob gram-negative (salmonella, E. coli, Klebsiella, Shigella). Cov tshuaj tseem cuam tshuam cov kab mob gram-positive (streptococci, staphylococci). Cov cuab yeej siv los kho cov kab mob pathologies los ntawm kev cuam tshuam ntawm cov kab mob intracellular microbes (chlamydia, tuberculous mycobacteria). Cov tshuaj no tseem siv tau rau hauv kev kho mob kis mob los ntawm Pseudomonas aeruginosa. Ciprolet 500 yog tsim nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj nrog lub ntsiab lus nquag ntawm 0.5 grams. Kuj tseem muaj cov tshuaj uas muaj cov tshuaj me me dua (250 mg). Tso tawm thiab daws rau Txoj kev lis ntshav. Cov tshuaj tiv thaiv yeeb yaj kiab yog Siflox, Ciprinol, Ciprofloxacin.

Kev ntsuas rau siv

Cov tshuaj "Tsiprolet 500" yog siv los kho mob ntawm pob ntseg, caj pas, ntswg, thiab mob ntsws. Nws siv hauv cov hlab ntsws ua rau mob staphylococci, hemophilic bacilli, legionella, Klebsiella, enterobacter tau pom. Nrog kev pabcuam ntawm cov tshuaj, kis tau tus mob ntawm cov qog ua kua xoos, lub plab zom mov, plab zom mov, tawv nqaij, qhov muag, cov nqaij mos, mob plab hnyuv siab raum, txhawb cov leeg mus rau lub cev, thiab lub plab me me yog kho. Siv tshuaj kho rau mob sepsis, peritonitis, prostatitis, pelvioperitonitis, adnexitis.

Cov tshuaj hauv tsis tseem ceeb ntawm cov tshuaj "Tsiprolet 500"

Nws yog txwv tsis pub siv cov tshuaj thaum cev xeeb tub, menyuam yaus hnub nyoog qis dua feem ntau, cov niam laus, nrog lub cev tsis muaj zog. Lawv siv tshuaj nrog kev ceev faj thaum muaj mob rau lub hlwb, raum tsis ua haujlwm, thiab mob siab, mob hlwb, thiab mob vwm. Nws tsis tsim nyog muab tshuaj rau cov laus.

Sab sij huam

Thaum siv cov tshuaj, qhov tshwm sim tsis zoo xws li psychosis, diplopia, pom kev lom zem, tinnitus, zoo nkaus li qaug zog, nce intracranial siab, mob taub hau, thiab insomnia tuaj yeem tshwm sim. Digestive plab hnyuv siab raum teb rau kev siv cov ntsiav tshuaj nrog mob raws plab, pom tus kheej, tsis qab los noj mov, ntuav, mob plab thiab xeev siab. Thaum kho, hypotension, tachycardia, cholestatic jaundice, sib koom tes thiab leeg mob, anaphylactic ceeb, urticaria, liab ntawm daim tawv thiab khaus yuav loj tuaj.

"Tsiprolet 500": cov lus qhia rau kev siv

Cov ntsiav tshuaj tau noj tsuas yog ua ntej noj mov, ntxuav nrog lub ntim loj ntawm cov kua. Cov koob tshuaj yog nyob ntawm qhov mob hnyav ntawm pathology, hnub nyoog ntawm tus neeg mob thiab nws lub cev qhov hnyav. Txog kev kho kab mob gonorrhea, noj 1 lub tshuaj Cyprolet (500 mg). Qhov ntim tib yam yog siv rau kev kho mob ntawm cov mob nyuaj ntawm mob txeeb zig, mob prostatitis, mob caj dab, mob txha hlwb, mob plab nkag.

Tso tawm daim ntawv thiab muaj pes tsawg leeg

Ciprolet muaj nyob hauv cov ntawv qhia hauv qab no:

Cov ntsiav tshuaj zaj duab xis: biconvex, puag ncig, nrog ib qhov chaw du ntawm ob sab, yuav luag dawb lossis dawb, pob txha tawg yog yuav luag dawb lossis dawb (10 daim hauv blisters, 1 lossis 2 blisters hauv cardboard bundle),
Kev daws rau Txoj kev lis ntshav: lub teeb daj, pob tshab, xim tsis muaj xim (100 ml txhua qhov hauv cov hwj tsis muaj polyethylene tsawg, 1 lub raj mis hauv lub thawv ntawv),,
Qhov muag dauv: pob tshab, lub teeb daj lossis xim tsis muaj xim (5 ml txhua tus hauv cov raj mis dropper, 1 lub raj mis hauv pob ntawv yas).

Cov muaj pes tsawg leeg ntawm 1 ntsiav tshuaj suav nrog:

Cov khoom siv nquag: ciprofloxacin - 250 lossis 500 mg (hauv daim ntawv ntawm ciprofloxacin hydrochloride monohydrate - 291.106 lossis 582.211 mg, ntsig txog),
Ntu cov khoom siv (250/500 mg, feem): pob kws hmoov txhuv - 50.323 / 27.789 mg, microcrystalline cellulose - 7.486 / 5 mg, talc - 5/6 mg, croscarmellose sodium - 10/20 mg, colloidal silicon dioxide - 5/5 mg, magnesium stearate - 3.514 / 4.5 mg,
Zaj duab xis sheath (250/500 mg, feem): polysorbate 80 - 0.08 / 0.072 mg, hypromellose (6 cps) - 4.8 / 5 mg, titanium dioxide - 2 / 1.784 mg, sorbic acid - 0.08 / 0.072 mg Macrogol 6000 - 1.36 / 1.216 mg, talc - 1.6 / 1.784 mg, dimethicone - 0.08 / 0.072 mg.

Cov tshuaj muaj pes tsawg leeg 100 ml ntawm kev daws rau infusion suav nrog:

Cov tshuaj kom nquag: ciprofloxacin - 200 mg,
Cov khoom siv pabcuam: sodium chloride - 900 mg, disodium edetate - 10 mg, lactic acid - 75 mg, citric acid monohydrate - 12 mg, sodium hydroxide - 8 mg, hydrochloric acid - 0.0231 ml, dej rau kev txhaj - txog 100 ml.

Cov tshuaj muaj pes tsawg leeg 1 ml ntawm cov tee qhov muag suav nrog:

Cov khoom siv nquag: ciprofloxacin - 3 mg (hauv daim ntawv ciprofloxacin hydrochloride - 3.49 mg),
Ntu cov khoom siv: disodium edetate - 0.5 mg, hydrochloric acid - 0.000034 mg, sodium chloride - 9 mg, benzalkonium chloride 50% daws - 0.0002 ml, dej rau kev txhaj tshuaj - txog 1 ml.

Kev ntsuas rau siv

Ciprolet nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj thiab ib qho kev daws teeb meem yog kho rau kev kho mob kis thiab mob los ntawm cov kab mob me me nkag siab rau kev ua ntawm ciprofloxacin, suav nrog:

Cov kab mob ntawm lub qog, ua pa tawm, mob tawm ntawm lub raum thiab lub raum, ENT kabmob, kua tsib lub plab thiab lub zais zis, tawv nqaij, cov nqaij mos thiab cov qog ua pa, cov leeg ua haujlwm, plab hnyuv (nrog rau cov hniav, qhov ncauj, puab tsaig)
Mob ntsws hnoos qeev
Sepsis.

Cov tshuaj yeeb yaj kiab tseem tseem siv hauv kev kho mob thiab tiv thaiv kev kis mob rau hauv cov neeg mob uas txo qis kev tiv thaiv (thaum siv tshuaj tiv thaiv kab mob).

Qhov muag dauv Ciprolet raug tshuaj rau kev kis kab mob thiab mob ntawm lub qhov muag thiab nws cov lus xaus tshwm sim los ntawm cov kab mob nkag rau qhov kev txiav txim ntawm cov tshuaj, suav nrog:

Blepharitis, blepharoconjunctivitis,
Kab mob tsis ncaj (subacute thiab mob siab),
Cov kab mob hauv lub qhov muag pom kev,
Mob dacryocystitis thiab mob meibomite,
Keratoconjunctivitis thiab kab mob keratitis.

Ncos kuj tau qhia txog kev kho qhov mob ua ntej thiab kev kho mob tom qab ntawm kev sib kis kab mob hauv ophthalmosurgery thiab rau qhov muag cuam tshuam tom qab noj cov kab mob txawv teb chaws lub cev lossis raug mob (kev kho mob thiab kev tiv thaiv).

Cov Yuav Tsum Tau Ua

Kev mob virat keratitis (rau mob qhov muag),
Pseudomembranous colitis (rau cov ntsiav tshuaj thiab tov rau Txoj kev lis ntshav),
Cov piam thaj-6-phosphate dehydrogenase deficiency (rau kev daws teeb meem),
Lub hnub nyoog txog li 1 xyoos (rau cov qhov muag pom kev) lossis txog 18 xyoo (rau ntsiav tshuaj thiab tov rau Txoj kev lis ntshav).

Cov Kev Txwv rau txhua daim ntawv tshaj tawm:

Cev xeeb tub thiab lactation
Cov tshuaj tiv thaiv tsis haum rau cov tshuaj ntawm cov tshuaj lossis lwm yam tshuaj los ntawm cov pab pawg ntawm fluoroquinolones.

Nrog kev ceev faj, Tsiprolet yuav tsum muaj kev kho mob hauv txhua daim ntawv qhia tshuaj rau cov neeg mob uas mob atherosclerosis ntawm cov hlab ntsha hauv lub hlwb, cov kab mob cerebrovascular thiab cov leeg mob huam.

Sab hauv thiab sib zog, cov tshuaj yuav tsum tau siv nrog ceev faj hauv cov neeg laus, nrog rau cov mob vwm, mob hlwb, mob nyhav hnyav thiab / lossis lub raum tsis ua haujlwm.

Tsuas tshuaj thiab tswj hwm

Qhov koob tshuaj Ciprolet yog txiav txim siab los ntawm daim ntawv tso tawm cov tshuaj, qhov hnyav ntawm tus kabmob, hom mob kis, tus mob ntawm lub cev, lub cev nyhav, hnub nyoog thiab kev ua haujlwm hauv lub raum.

Ciprolet nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj yog noj ntawm qhov ncauj, ntawm lub plab khoob, nrog dej ntau.

Raws li txoj cai, cov tshuaj hauv qab no yog tshuaj:

Cov mob uas tsis yooj yim ntawm cov mob txeeb zig thiab lub raum, cov kab mob ntawm cov pa hauv lub ntsws qis ntawm kev mob nyav: 2 zaug hauv ib hnub, 250 mg txhua zaus, ntawm tus mob hnyav, ib koob tshuaj ib zaug tuaj yeem nce 2 zaug,
Gonorrhea: 250-500 mg ib zaug,
Gynecological kab mob, enteritis thiab colitis nrog rau chav kawm hnyav thiab kub taub hau, mob prostatitis, osteomyelitis: 500 mg 2 zaug hauv ib hnub (hauv kev kho mob ntawm kev mob plab ib txwm, ib koob tshuaj tuaj yeem txo los ntawm 2 zaug).

Lub sijhawm kho yog txiav txim siab los ntawm tus mob hnyav, tab sis Ciprolet yuav tsum noj tsawg kawg 2 hnub tom qab ploj ntawm cov cim ntawm tus kab mob. Qhov nruab nrab, lub sijhawm ua haujlwm yog 7-10 hnub.

Yog tias muaj mob raum ntau, 1 /₂ kev txhaj tshuaj.

Hauv mob raum tsis ua hauj lwm, qhov tshuaj tsuas yog txiav txim los ntawm creatinine clearance:

Ntau tshaj 50 ml ib feeb: noj tsuas siv
30-50 ml ib feeb: 1 zaug hauv 12 teev, 250-500 mg txhua,
5-29 ml ib feeb: ib zaug txhua 18 teev, 250-500 mg.

Cov neeg mob tau mob hemo- lossis peritoneal lim ntshav tau txais tshuaj ib zaug txhua 24 teev nrog 250-500 mg (tom qab lim ntshav).

Ciprolet nyob rau hauv daim ntawv ntawm kev daws rau kev lis ntshav yog muab tshuaj rau hauv lub cev poob rau 30 feeb (200 mg txhua) thiab 60 feeb (400 mg txhua).

Txoj kev daws teeb meem yog sib xws nrog Ringer txoj kev daws teeb meem, 0.9% sodium chloride tov, 10% fructose tov, 5% thiab 10% dextrose tov, nrog rau cov tshuaj muaj 5% dextrose tov nrog 0.45% lossis 0.225% sodium chloride tov.

Qhov nruab nrab ib koob tsuas yog 200 mg (rau mob hnyav - 400 mg), ntau zaus ntawm kev tswj hwm - 2 zaug ib hnub. Lub sijhawm kho yog txiav txim los ntawm qhov mob hnyav ntawm tus kabmob thiab qhov nruab nrab 7-14 hnub. Yog tias tsim nyog, cov tshuaj no tuaj yeem siv sijhawm ntev.

Hauv kev kho mob ntawm tus kab mob gonorrhea mob, ib qho kev tso tawm ib leeg ntawm 100 mg ntawm kev daws yog qhia.

Txog kev tiv thaiv kab mob tom qab kis tas, Ciprolet muab tshuaj rau 200-400 mg 30-60 feeb ua ntej kev phais mob.

Cyprolet nyob rau hauv daim ntawv ntawm cov kua muag pom tau thov pleev.

Thaum muaj mob me thiab mob hnyav, txhua 4 teev twg, 1-2 ncos tau tso rau hauv hnab looj tes sib txuas ntawm lub qhov muag cuam tshuam, yog muaj mob hnyav, 2 ncos txhua teev. Tom qab kev txhim kho, cov zaus ntawm instillations thiab cov koob tshuaj tau txo.

Hauv kev kho mob ntawm cov kab mob ua paug rau pob ntseg raws txoj cai:

Hnub 1: txhua 15 feeb, 1 poob rau 6 teev, tom qab ntawd txhua 30 feeb thaum lub sijhawm so, 1 poob,
Thib 2 - txhua teev thaum lub sijhawm so, 1 poob,
Hnub Thib 14-Hnub - txhua 4 teev nyob rau lub sijhawm tsim tsa, 1 poob.

Yog tias tom qab 14 hnub ntawm kev kho mob epithelization tsis tau tshwm sim, txoj kev kho tuaj yeem txuas ntxiv.

Sab sij huam

Thaum lub sijhawm siv Ciprolet sab hauv thiab ncau, cov kev mob tshwm sim hauv qab no:

Lub plawv mob: lub plawv dhia tsis xwm yeem, tachycardia, txo qis ntshav siab, yaug ntsej muag,
Cov kab mob hauv lub raum: interstitial nephritis, hematuria, crystalluria (feem ntau nrog qis diuresis thiab alkaline zis), glomerulonephritis, polyuria, dysuria, albuminuria, tso zis cia, tso zis ntshav, txo lub raum cia tsis ua haujlwm,
Musculoskeletal system: leeg pob txha caj qaum, mob caj dab, mob caj dab, mob caj dab, mob leeg ntshav,
Hematopoietic system: thrombocytosis, granulocytopenia, leukopenia, thrombocytopenia, anemia, leukocytosis, hemolytic anemia,
Lub plab zom mov: tsis nco qab, mob plab, xeev siab, ntuav, raws plab, mob plab, cholestatic jaundice (tshwj xeeb tshaj yog nyob rau cov neeg mob uas muaj kab mob siab yav dhau los), mob hepatonecrosis, mob siab, nce kev ua haujlwm ntawm hepatic transaminases thiab alkaline phosphatase,
Lub cev tsis muaj zog: mob taub hau, kiv taub hau, tshee tshee, qaug zog, pw tsaug zog, npau suav phem, peripheral paralgesia (tsis nco qab qhov pom ntawm qhov mob), mob siab intracranial, tawm hws, ntxhov siab, ntxhov siab, tsis meej pem, hnov meej, thiab lwm yam kev puas siab puas ntsws (qee zaus lawv tuaj yeem hloov mus rau cov xwm txheej uas tus neeg mob muaj peev xwm ua rau nws tus kheej raug mob), tsaus muag, mob taub hau, mob hlwb o
Cov kabmob hauv lub cev: hnov lus tsis zoo, lub plab me me, lub qhov hnov tsw thiab hnov qab, qhov muag tsis pom (daim ntawv pov thawj, hloov pauv hloov xim)
Kev ntsuas ntsuas: hypercreatininemia, hypoprothrombinemia, hyperglycemia, hyperbilirubinemia,
Kev ua xua: qhov pom ntawm pob txuv ntawm lub pob tw me me thiab cov hlwv nrog ua rau los ntshav, khaus tawv nqaij, kub cev tshuaj, urticaria, pom mob hemorrhages (petechiae), vasculitis, laryngeal lossis ntsej muag, eosinophilia, ua tsis taus pa, nce ntawm photosensitivity, erythema nodosum, muaj mob ua paug ntawm lub cev. cov mob ua paug (Lyell's syndrome), Stevens-Johnson syndrome (malignant exudative erythema),
Lwm yam: kev ua kom tsis muaj zog, kev saib xyuas qhov tseeb (mob ua paug, mob ntshav liab).

Nrog kev tswj hwm hauv qhov quav, cov tshuaj tiv thaiv hauv ib cheeb tsam yuav tshwm sim, pom los ntawm qhov mob thiab hlawv ntawm qhov chaw txhaj tshuaj, kev txhim kho phlebitis.

Thaum siv Ciprolet nyob rau hauv kev sib txuas ntawm qhov muag, qhov tshwm sim hauv qab no yuav tshwm sim:

Lub cev ntawm lub zeem muag: kev kub hnyiab, khaus, hyperemia thiab mob me me ntawm lub qhov muag, tsis tshua muaj photophobia, o ntawm daim tawv muag, lacrimation, txawv teb chaws lub cev kev xav hauv lub qhov muag, txo qhov muag pom, qhov pom ntawm dawb crystalline precipitate nyob rau hauv cov neeg mob uas mob caj dab, keratopathy, keratitis, mob rau lub ntsej muag,
Lwm yam: xeev siab, kev tsis haum tshuaj, tsis tshua muaj - kev txhim kho ntawm superinfection, ib qho tsis zoo tom qab lub qhov ncauj tom qab instillation.

Cov lus qhia tshwj xeeb

Cov neeg mob qaug dab peg, keeb kwm ntawm qaug dab peg, kab mob vascular thiab cov hlwb hauv lub hlwb vim qhov kev hem thawj ntawm cov kev phiv tshuaj los ntawm lub hauv nruab nrab cov hlab ntsha yuav tsum yog Ciprolet sab hauv vim kev noj qab haus huv nkaus xwb.

Yog tias thaum lub sijhawm lossis tom qab siv cov tshuaj, ntev lossis mob plab zawv plab tshwm sim sab hauv lossis ncau, nws yog qhov yuav tsum tau cais tawm muaj pseudomembranous mob plab, uas yuav tsum tau tshem tawm tam sim ntawm Ciprolet thiab kev teem sijhawm kho kom tsim nyog. Kev kho yuav tsum tau tsum tsis ua ntxiv nrog kev txhim kho ntawm kev mob ntawm txoj leeg nqaij los yog nrog cov tsos ntawm cov tsos mob ntawm thawj tus mob.

Thaum lub sij hawm siv cov tshuaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj thiab tov rau Txoj kev lis ntshav, cov kua dej txaus yuav tsum tau muab thaum saib cov diuresis dab tsi.

Qhov muag dauv Ciprolet tuaj yeem siv tsuas yog raug sau, nws yog tsis yooj yim sua kom txhaj tshuaj rau hauv chav ua ntej ntawm qhov muag lossis subconjunctival. Thaum siv cov tshuaj thiab lwm qhov kev daws teeb meem ophthalmic, lub sijhawm nruab nrab ntawm lawv cov kev tswj hwm yuav tsum yog tsawg kawg 5 feeb. Looj lub looj tsom iav tsis pom zoo thaum kho.

Thaum siv Tsiprolet, kev saib xyuas yuav tsum tau saib xyuas thaum tsav tsheb thiab ua lwm yam kev muaj peev xwm ua haujlwm uas xav tau kev kub siab thiab ceev cov kev xav psychomotor (tshwj xeeb tshaj yog ua ke nrog cawv).

Yeeb tshuaj sib cuam tshuam

Nyob rau hauv cov ntaub ntawv ntawm tib lub sijhawm siv Ciprolet nrog qee yam tshuaj, qhov teebmeem tsis xav yuav tshwm sim:

Didanosine: poob qis ntawm ciprofloxacin,
Theophylline: kev ua kom pom tseeb hauv nws cov ntshav plasma thiab qhov kev pheej hmoo ntawm kev tsim cov tshuaj lom,
Cov tshuaj tiv thaiv kab mob, nrog rau kev npaj muaj zinc, aluminium, magnesium lossis hlau ions: txo qhov nqus ntawm ciprofloxacin (qhov sib txawv nruab nrab ntawm kev siv nrog cov tshuaj no yuav tsum yog tsawg kawg 4 teev),
Anticoagulants: lub sijhawm ntev los ntshav,
Cyclosporin: nce nephrotoxicity,
Cov tshuaj nonsteroidal anti-inflammatory (tshwj tsis yog acetylsalicylic acid): muaj kev pheej hmoo ntawm qaug dab peg,
Metoclopramide: nrawm nrawm ntawm ciprofloxacin,
Kev npaj Uricosuric: ncua kev tshem tawm thiab nce ntshav ntau ntxiv ntawm ciprofloxacin,
Indirect anticoagulants: txhim kho lawv qhov kev txiav txim.

Nrog tib lub sijhawm siv Ciprolet nrog lwm cov tshuaj tua kab mob, kev sib txuam ntawm kev ua yog tau. Raws li kev kis tus mob, Ciprolet tuaj yeem siv ua ke nrog cov tshuaj hauv qab no:

Azlocillin, ceftazidime: mob los ntawm Pseudomonas spp.,
Meslocillin, azlocillin thiab lwm yam tshuaj tua kab mob beta-lactam: cov kab mob streptococcal,
Isoxazolylpenicillins thiab vancomycin: kab mob staph,
Metronidazole, clindamycin: kab mob anaerobic.

Ciprolet Txoj kev lis ntshav kua tshuaj yog tshuaj tsis sib haum nrog txhua yam tshuaj thiab txoj kev lis ntshav daws teeb meem uas lub cev thiab tshuaj tsis ruaj nyob hauv cov kua qaub (cov pH ntawm ciprofloxacin infusion daws yog 3.5-4.6). Nws yog tsis yooj yim sua kom muab cov tshuaj rau kev tswj hwm nrog kev daws teeb meem uas pH ntau dua 7.