Gliformin ntsiav tshuaj: kev taw qhia rau kev siv, phiv thiab analogues tshuaj

Tus neeg sawv cev ntawm lub cev hypoglycemic los ntawm cov pab pawg biguanide.
Npaj: GLYFORMIN®
Cov tshuaj nquag ntawm cov tshuaj: metformin
ATX Encoding: A10BA02
KFG: Qhov ncauj tshuaj hypoglycemic
Npe sau npe: P No. 003192/01
Hnub tso npe: 04/21/04
Tswv reg reg. doc .: Tshuaj thiab tshuaj cog AKRIKHIN OJSC

Tso tawm daim ntawv thiab muaj pes tsawg leeg

Daim ntawv tsuas tshuaj ntawm Gliformin yog cov ntsiav tshuaj.

Cov tshuaj nquag ua haujlwm ntawm cov tshuaj yog metformin hydrochloride. Qhov nws mob siab hauv ib ntsiav tshuaj tuaj yeem yog 500 mg, 850 mg lossis 1 gram.

Ntu cov khoom siv ntawm 500 mg ntsiav tshuaj yog calcium phosphate dihydrate, sorbitol, povidone (polyvinylpyrrolidone), stearic acid los yog calcium stearate, macrogol (polyethylene glycol). 60 daim raug muag. hauv cov thawv ntawv thawv (6 lub blister ntim muaj 10 ntsiav tshuaj txhua).

Cov tshuaj ntxiv ntawm Glyformin 850 mg thiab 1 gram ntsiav tshuaj yog qos hmoov txhuv nplej siab, stearic acid, povidone (polyvinylpyrrolidone). Ntawm cov tshuaj no, 60 ntsiav tshuaj yog muag. hauv polypropylene cov kaus poom.

Cov Tshuaj Hauv Tshuaj

Metformin yog qhov ncauj tshuaj hypoglycemic uas yog nyob rau qeb ntawm biguanides. Nws txo cov tsos mob hyperglycemic, thiab qhov kev pheej hmoo ntawm hypoglycemia yog tsawg heev. Tsis zoo li sulfonylurea derivatives, cov tshuaj tsis txhawb kev tsim tawm ntawm cov tshuaj insulin thiab tsis muaj qhov cuam tshuam los ntawm cov nyhuv hypoglycemic thaum siv hauv cov neeg ua haujlwm zoo.

Metformin tsub kom qhov kev nkag siab tseem ceeb rau cov khoom siv sab nrauv rau insulin thiab txhim kho kev siv cov ntshav qabzib ntau hauv cov hlwb, thiab tseem muaj kev cuam tshuam ntawm gluconeogenesis nyob rau hauv daim siab thiab inhibits qhov nqus ntawm carbohydrates hauv txoj hnyuv. Metformin ua kom cov khoom lag luam glycogen ua los ntawm kev ua yeeb yam ntawm glycogen synthase thiab ua rau muaj peev xwm thauj ntau ntawm txhua yam ntawm cov khoom thauj qis.

Glyformin kuj tseem cuam tshuam cuam tshuam lipid metabolism, txo qhov concentration ntawm triglycerides, qis lipoproteins tsawg thiab tag nrho cov cholesterol. Tawm tsam tom qab ntawm kev kho mob nrog metformin, tus neeg mob lub cev qhov hnyav tseem tsis hloov, lossis txo qis me ntsis.

Cov Tshuaj Pharmacokinetics

Tom qab cov neeg siv qhov ncauj, metformin yog nqus los ntawm cov hnyuv zom tag nrho. Nws qhov tseeb txog qhov tsis tuaj yeem loj txog 50-60%. Qhov siab tshaj plaws ntawm ib yam khoom hauv ntshav tau txog kwv yees li 2.5 teev tom qab kev tswj hwm thiab yog 15 μmol, lossis 2 2g / ml. Thaum noj cov tshuaj metformin nrog rau cov zaub mov, nws txoj kev nqus qis thiab txo qis qis. Nws muab faib nrawm thoob plaws cov ntaub so ntswg ntawm lub cev, xyaum tsis txhob khi rau cov protein ntau.

Metformin tshuaj tiv thaiv kab mob me me thiab txhaws hauv cov zis. Nws txoj kev tshem tawm hauv cov neeg tuaj yeem noj qab haus huv yog 400 ml / min (uas yog 4 npaug ntau dua li creatinine tshem tawm), uas ua pov thawj qhov tsis pom muaj cov tubular ua kom zoo. Ib nrab-lub neej yog kwv yees li 6,5 teev. Nrog raum tsis ua haujlwm, nws nce, uas ua rau muaj kev pheej hmoo ntawm kev txuam nrog cov tshuaj.

Kev ntsuas rau siv

Gliformin tau sau tseg rau hauv kev kho mob ntawm:

• yam II mob ntshav qab zib mellitus, thaum tshuaj tsis zoo sulfonylureas thiabkev kho kev noj haus,
• yam kuv mob ntshav qab zib raws li ib qho ntxiv rau kev kho mob insulin.

Cov Yuav Tsum Muaj

Nws tsis pom zoo kom noj cov tshuaj no nrog:

• mob ntshav qab zib coma thiab precomatous tej yam kev mob
• ketoacidosis,
• kis kab mob
• qhov txhab ntawm daim siab thiab lub raum,
• hlab plawv lossis hlab plawv tsis ua haujlwm,
• mob myocardial infarction,
• lactation, cev xeeb tub.

Cov lus qhia rau kev siv ntawm Gliformin (Txuj ci thiab ntau npaum li cas)

Raws li tau qhia los ntawm cov lus qhia rau kev siv Gliformin, cov ntsiav tshuaj yog noj ntawm qhov ncauj. Hauv qhov no, thawj 3 hnub, cov neeg mob tau kho 500 mg rau 3 koob tshuaj ib zaug thaum nruab hnub, tib lub sijhawm lossis tom qab noj mov. Tom qab ntawd qhov tsuas tshuaj yog maj mam nce mus rau 1 g. Feem ntau, kev saib xyuas txhua hnub ntau npaum li yog 0.1-0.2 g.

Noj ntau dhau

Nyob rau hauv cov ntaub ntawv ntawm overdose yuav tshwm sim lactic acidosisneeg tuag taus. Lub ntsiab yog vim li cas rau nws txoj kev loj hlob yog kev ntseeg siab. metformin vim yog mob raum tsis zoo muaj nuj nqi. Thaum nyuam qhuav pib tshwm: xeev siab, ntuav, raws plab, kev ua kom tsis muaj zog, txo qis kub, mob plab thiab mob nqaij, poob qis, lub zog bradyarrhythmia. Tom qab ntawd ua pa sai duakiv taub hautsis nco qab zoo li kev loj hlob coma.

Thaum cov tsos mob tshwm sim lactic acidosis koj yuav tsum tam sim ntawd tsum tsis txhob noj Gliformin. Kev kho ntxiv yog nqa hauv tsev kho mob, yog li tus neeg mob yuav tsum tau mus pw hauv tsev kho mob, teeb tsa qhov kev xav ntawm lactate, lees tias txoj kev kuaj mob. Cov txheej txheem zoo hemodialysispab txhawm rau tshem tawm ntawm lub cev lactate thiab metforminCov. Ua ntxiv rau cov tsos mob zoo nkauj kuj tseem ua.

Glyformin tso tawm daim ntawv, ntim tshuaj thiab muaj pes tsawg leeg.

Cov ntsiav tshuaj yog dawb lossis yuav luag dawb, pav ca-cylindrical, nrog bevel thiab nqis siab tshaj.

1 tab
metformin (nyob rau hauv daim ntawv ntawm hydrochloride)
250 mg
-«-
500 mg

Cov muaj mob: sorbitol, calcium phosphate dihydrate, polyvinylpyrrolidone (povidone), polyethylene glycol (macrogol), calcium stearate lossis stearic acid.

10 Pcs - blister packs (3) - pob ntawv ntawm cardboard.
10 Pcs - blister packagings (6) - pob ntawv ntawm cardboard.
10 Pcs - blister pob khoom (10) - pob ntawv ntawm cardboard.
60 pcs. - cov kaus poom ntawm cov iav dub (1) - pob khoom los ntawm cardboard.
100 pcs - cov kaus poom ntawm cov iav dub (1) - pob khoom los ntawm cardboard.

LUS PUB HUAM TXHEEJ TXHEEM MOO ZOO.
Txhua cov lus qhia tau muab nthuav tawm tsuas yog ua rau kom paub txog cov tshuaj, koj yuav tsum sab laj nrog tus kws kho mob txog kev siv.

Pharmacological kev ua ntawm glyformin

Qhov ncauj hypoglycemic tus neeg sawv cev los ntawm pab pawg ntawm biguanides (dimethylbiguanide). Tus txheej txheem ntawm kev ua ntawm metformin yog txuam nrog nws lub peev xwm los txwv gluconeogenesis, nrog rau kev tsim cov roj dawb dawb thiab oxidation ntawm cov rog. Metformin tsis cuam tshuam rau cov tshuaj insulin hauv cov ntshav, tab sis hloov nws cov chaw muag tshuaj los ntawm kev txo qis ntawm qhov khi ntawm cov insulin kom dawb thiab nce qhov feem ntawm cov insulin rau proinsulin. Qhov kev sib txuas tseem ceeb hauv cov txheej txheem ntawm kev ua ntawm metformin yog qhov kev xav ntawm cov piam thaj los ntawm cov leeg nqaij.

Metformin txhim kho cov ntshav ncig hauv lub siab thiab ua kom nrawm hloov pauv ntawm cov piam thaj rau glycogen. Txo cov qib triglycerides, LDL, VLDL. Metformin kho txhim kho cov khoom fibrinolytic ntawm cov ntshav los ntawm kev tiv thaiv cov nqaij mos-plasminogen activator inhibitor.

Dosage thiab txoj hauv kev ntawm kev tswj hwm tshuaj.

Rau cov neeg mob tsis tau txais insulin, hauv thawj 3 hnub - 500 mg 3 zaug / hnub lossis 1 g 2 zaug / hnub thaum lossis tom qab noj mov. Txij hnub tim 4 mus txog rau hnub 14 - 1 g 3 zaug / hnub. Tom qab 15 hnub, qhov hno tshuaj tau raug hloov kho mus rau hauv tus account qib ntawm cov piam thaj hauv cov ntshav thiab zis. Kev saib xyuas txij nkawm yog 100-200 mg / hnub.

Nrog rau kev siv tshuaj insulin ib txhij ntawm ib koob tsawg dua 40 units / hnub, kev noj tshuaj ntawm cov tshuaj metformin yog qhov qub, thaum lub koob tshuaj insulin tuaj yeem maj mam txo qis (los ntawm 4-8 units / hnub txhua lwm hnub). Yog tias tus neeg mob tau txais ntau dua 40 units / hnub, tom qab ntawd kev siv cov metformin thiab txo qis ntawm cov tshuaj insulin yuav tsum muaj kev saib xyuas zoo thiab raug coj hauv tsev kho mob.

Sab nyhuv ntawm glyformin:

Los ntawm lub plab zom mov: ua tau (feem ntau thaum pib kho) xeev siab, ntuav, raws plab.

Los ntawm cov kab mob endocrine: hypoglycemia (feem ntau yog siv thaum tsis txaus noj).

Los ntawm sab ntawm cov metabolism: hauv qee kis - lactic acidosis (yuav tsum muaj kev tso tseg kev kho mob).

Los ntawm cov kab mob hemopoietic: qee kis - megaloblastic anemia.

Contraindications rau cov tshuaj:

Kev ua txhaum ntawm daim siab thiab lub raum, lub plawv thiab lub ntsws tsis ua haujlwm, mob sai ntawm myocardial infarction, kev haus dej cawv ntev, mob ntshav qab zib tsis nco qab, ketoacidosis, lactic acidosis (suav nrog keeb kwm), mob ntshav qab zib ko taw, cev xeeb tub, lactation, hypersensitivity rau metformin.

TEJ YEEM THIAB LUS
Contraindicated nyob rau hauv cev xeeb tub thiab lactation.

Cov lus qhia tshwj xeeb rau kev siv glyformin.

Nws tsis pom zoo rau mob hnyav, dhau mus ua kab mob sib kis thiab mob o, raug mob, mob phais mob sai, thiab muaj kev puas tsuaj ntawm lub cev qhuav dej.

Tsis txhob siv ua ntej kev phais thiab tsis pub dhau 2 hnub tom qab lawv tau ua.

Nws tsis pom zoo kom siv cov metformin hauv cov neeg mob hnub nyoog tshaj 60 xyoo thiab cov neeg ua haujlwm hnyav lub cev, uas cuam tshuam nrog kev pheej hmoo ntawm kev tsim mob lactic acidosis.

Thaum lub sijhawm kev kho mob, nws yog qhov yuav tsum tau soj ntsuam lub raum kev ua haujlwm, qhov kev txiav txim siab ntawm cov ntsiab lus lactate hauv ntshav yuav tsum tau nqa tsawg kawg 2 zaug hauv ib xyoos, nrog rau cov tsos ntawm myalgia.

Metformin tuaj yeem siv ua ke nrog sulfonylureas. Hauv qhov no, tshwj xeeb tshaj yog saib xyuas cov ntshav ntshav qab zib kom tsim nyog.

Kev siv cov metformin ua ib feem ntawm kev sib xyaw ua ke nrog kev siv tshuaj insulin yog raug pom zoo hauv tsev kho mob.

Gliformin sib cuam tshuam nrog lwm yam tshuaj.

Nrog rau kev siv tib txhij nrog sulfonylurea derivatives, acarbose, insulin, salicylates, MAO inhibitors, oxytetracycline, ACE inhibitors, nrog clofibrate, cyclophosphamide, cov nyhuv hypoglycemic ntawm metformin tej zaum yuav ua kom zoo dua.

Nrog rau kev siv ua ke nrog GCS, tshuaj tiv thaiv qog rau kev tswj hwm qhov ncauj, adrenaline, glucagon, cov thyroid hormones, phenothiazine derivatives, thiazide diuretics, nicotinic acid derivatives, txo qis hauv cov nyhuv hypoglycemic ntawm metformin yog ua tau.

Kev siv cov cimetidine ntau heev yuav ua rau muaj kev pheej hmoo ntawm tus mob lactic acidosis.

Cov lus qhia rau kev siv ntawm Gliformin: txoj kev thiab ntau npaum li cas

Cov ntsiav tshuaj Glyformin yog noj ntawm qhov ncauj thaum noj mov lossis tom qab, tsis tas yuav zom, nrog dej ntau.

Tus kws kho mob sau ntawv qhov ntau npaum li cas thiab lub sijhawm rau kev tswj hwm tus kheej, coj mus rau theem tus lej ntawm cov piam thaj hauv cov ntshav.

Thaum pib ntawm kev kho mob, thawj zaug 10-15 hnub, cov koob tshuaj yuav yog li ntawm 0.5 mus rau 1 g ib hnub ib zaug, tom qab ntawd, nyob ntawm seb muaj suab thaj hauv cov ntshav ntau npaum li cas, nws tuaj yeem maj mam nce ntxiv. Cov koob tshuaj saib xyuas, raws li txoj cai, yog 1.5-2 g ib hnub, muab faib ua 2-3 koob.

Qhov siab tshaj plaws txhua hnub koob ntawm Gliformin yog 3 g.

Rau cov neeg mob laus, cov tshuaj ntau tshaj yog 1 g nyob rau ib hnub.

Thaum muaj teeb meem loj ntawm lub cev cov teeb meem, qhov koob tshuaj yog pom zoo kom txo qis, txij li kev pheej hmoo ntawm cov kab mob lactic acid nce.

Sab sij huam

• Los ntawm cov kab ke endocrine: nyob rau hauv rooj plaub ntawm kev siv ntau dhau - hypoglycemia,
• Los ntawm lub plab zom mov: tsis muaj qab los noj mov, mob plab, xeev siab, hnov ​​qab hauv plab hauv lub qhov ncauj, raws plab, ntuav, flatulence (cov tsos mob no yog cov xeeb ceem rau kev pib kho, tom qab ntawd qhov xwm txheej ib txwm ua),,
• Los ntawm cov kab mob hemopoietic: qee zaum - megaloblastic anemia,
• Los ntawm sab ntawm cov metabolism: nrog kev kho mob ntev - hypovitaminosis B₁₂, muaj qee zaus, cov kab mob lactic acidosis,
• Kev ua xua rau: xoo pob khaus.

Yog tias muaj kev mob tshwm sim, nws yog qhov yuav tsum tau rho tawm Glyformin ib ntus thiab sab laj nrog kws kho mob.

Cov lus qhia tshwj xeeb

Txoj kev kho yuav tsum nrog soj ntsuam cov ntshav qabzib kom tsis tu ncua.

Thaum lub sijhawm kho, cov kev tshawb fawb yuav tsum tau ua txhua txhua rau lub hlis los txiav txim siab txog qib ntawm lactate thiab creatinine hauv ntshav ntshav. Lub raum kev ua haujlwm tshwj xeeb tshaj yog saib xyuas hauv cov neeg laus. Glyformin yuav tsum tsis txhob raug rau cov txiv neej nrog qib siab creatinine siab dua 135 μmol / L, rau cov poj niam - 110 μmol / L.

Cov kev mob tshwm sim los ntawm lub plab zom mov tuaj yeem raug txo qis los ntawm kev siv tib lub sijhawm ntawm antacids lossis antispasmodics.

Lub sijhawm kho yuav tsum tsis pub haus dej cawv thiab cov khoom ntim uas muaj ethanol.

Nrog rau monotherapy, Gliformin tsis cuam tshuam rau lub peev xwm los tsav tsheb thiab ua haujlwm nrog cov txheej txheem.

Thaum noj cov tshuaj Gliformin nrog rau lwm cov kab mob hypoglycemic, suav nrog insulin, sulfonylureas, nws yog qhov yuav tsum tau ceev faj thaum tsav tsheb thiab ua cov haujlwm txaus ntshai uas xav kom muaj kev kub ceev ntawm psychomotor cov kev cuam tshuam thiab nce siab.

Cev xeeb tub thiab lactation

Kev siv cov metformin thaum cev xeeb tub thiab kev pub niam mis yog contraindicated.

Thaum npaj kev cev xeeb tub, zoo li yog tias nws tau tshwm sim thaum kho nrog Gliformin, cov tshuaj tau tso tseg thiab kev kho mob insulin yog yam mob.

Nws tsis tau hais meej meej tias seb cov tshuaj metformin xa mus rau niam cov kua mis, yog li Glyformin yuav tsum tsis txhob raug tshuaj thaum lactation. Yog tias nws qhov tseem ceeb heev, kev pub mis niam yuav tsum tsis ua mus ntxiv.

Yeeb tshuaj sib cuam tshuam

Nws yog ua tau los txhim kho qhov kev ua ntawm Glyformin nrog kev siv tib lub sijhawm nrog insulin, beta-blockers, sulfonylureas, tshuaj tsis-steroidal anti-inflammatory, acarbose, monoamine oxidase inhibitors, angiotensin hloov enzyme inhibitors, oxytetracycline, cyclophosphamide, thiab lwm yam.

Cov nyhuv ntawm Gliformin yuav raug txo qis thaum siv glucagon, glucocorticosteroids, tshuaj tiv thaiv qhov ncauj, cov thyroid hormones, epinephrine, sympathomimetics, "voj" thiab thiazide diuretics, derivatives ntawm nicotinic acid thiab phenothiazine.

Kev siv cov pa tshuaj ua ke nrog cov tshuaj pleev ua rau cov kab mob ua rau lub zog ntawm cov kab mob lactic acidosis.

Kev tshem tawm ntawm Glyformin qeeb qeeb thaum ua ke nrog cimetidine, qhov ntxim nyiam ntawm kev lactic acidosis nce ntxiv.

Nrog rau kev coj ua ke nrog cov tshuaj tiv thaiv anticoagulants, coumarin derivatives, lawv cov nyhuv raug txo kom tsawg.

Gliformin's analogues yog: Glucofage, Glucofage Ntev, Glukoran, Gliguanid, Dformin, Diaberit, Diabetosan, Diabexil, Diguanil, Metformin, Melbin, Mellitin, Metiguanid, Modulan, Formmetin.

Kev txheeb xyuas txog Gliformin

Raws li kev tshuaj xyuas ntawm Gliformin, nws muaj txiaj ntsig ob qho tib si tus kab mob ntshav qab zib mellitus thiab hauv ntau yam teeb meem hauv lub cev zom zaub mov. Tsis tas li, feem ntau nws siv los ntawm cov neeg mob tshawb nrhiav kom poob phaus, thiab qee cov neeg siv nws rau cov laj thawj no tau lees tias lawv muaj peev xwm pom poob ceeb thawj thiab ua tsis tau cov tshuaj hormones. Txawm li cas los xij, ntau tus kws tshaj lij ceeb toom tawm tsam kev siv ntawm Gliformin rau qhov poob phaus, yog tias tsis muaj kev ntsuas nruj rau qhov no.

Qee tus neeg mob tau hais txog qhov tshwm sim tsis zoo ntawm cov tshuaj, suav nrog mob taub hau, tsis muaj zog, mob plab tsis ua hauj lwm. Txij li nws muaj peev xwm tawm ntawm ob qho tib si zoo thiab tsis zoo rau lub cev, nws raug pom zoo kom yauv mus rau ib txoj kev kho mob nruj raws li kev saib xyuas ntawm tus kws kho mob.

Tus nqi ntawm Gliformin hauv cov khw muag tshuaj

Tus nqi kwv yees ntawm Gliformin 0.5 g ntsiav tshuaj hauv khw muag tshuaj yog 86-130 rubles (pob muaj 60 ntsiav tshuaj). Koj tuaj yeem yuav cov ntsiav tshuaj hauv zaj duab xis txheej nrog qhov tshuaj ntawm 0.85 g rau kwv yees li 191-217 rubles, thiab ntau npaum li 1 g rau 242–329 rubles (txhua pob muaj 60 ntsiav tshuaj).

Gliformin: cov nqi hauv cov khw muag online

GLYFORMIN 500mg 60 pcs. zaj duab xis-ntsiav tshuaj ntsiav tshuaj

Gliformin 0.85 g zaj duab xis-coated ntsiav tshuaj 60 pcs.

Kev Kawm: Rostov State Medical University, tshwj xeeb "General Tshuaj".

Cov ntaub ntawv hais txog cov tshuaj raug muab dav dav, muab rau kev qhia tawm thiab tsis hloov chaw cov lus qhia. Kev siv tshuaj rau tus kheej yog qhov txaus ntshai rau kev noj qab haus huv!

Raws li kev tshawb fawb, cov poj niam uas haus ob peb khob npias lossis cawv txiv hmab ib lim tiam muaj feem ntau yuav muaj mob khees xaws mis.

Raws li ntau tus kws tshawb fawb, cov vitamins complex yog qhov tsis muaj txiaj ntsig rau tib neeg.

Hauv kev mob siab kom tau tus neeg mob tawm, cov kws kho mob feem ntau mus deb dhau. Yog li, piv txwv li, qee yam Charles Jensen nyob rau lub sijhawm txij xyoo 1954 txog 1994. muaj sia nyob ntau dua 900 lub neoplasm tshem tawm txoj haujlwm.

Thaum lub neej, tus neeg nruab nrab tsim tawm tsis tsawg tshaj li ob lub pas dej loj uas muaj qaub ncaug.

Plaub qho ntawm chocolate tsaus muaj txog ob puas calories. Yog li yog tias koj tsis xav tau zoo dua, nws zoo dua tsis txhob noj ntau tshaj li ob lobules ib hnub.

Raws li kev txheeb cais, nyob rau hnub Monday, kev pheej hmoo ntawm nraub qaum nce ntxiv li 25%, thiab kev pheej hmoo ntawm mob plawv - los ntawm 33%. Kom ceev faj.

Ntxiv rau tib neeg, tsuas yog ib tus tsiaj muaj sia nyob ntawm ntiaj chaw ntiaj teb - dev, raug kev txom nyem los ntawm prostatitis. Cov no yog peb cov phooj ywg ncaj ncees tshaj plaws.

Ntau lab tus kab mob tau yug, ciaj thiab tuag hauv peb lub plab. Lawv tuaj yeem pom tsuas yog txhawb nqa siab, tab sis yog tias lawv tuaj ua ke, lawv yuav haum rau hauv lub khob kas fes.

Cov kws tshawb fawb Asmeskas tau sim cov nas thiab tau xaus lus tias cov kua txiv mab txiv ntoo txwv tsis pub muaj kev txhim kho ntawm cov hlab ntshav atherosclerosis ntawm cov hlab ntshav. Ib pawg nas haus dej dawb, thiab lub thib ob ua kua txiv. Raws li qhov tshwm sim, cov hlab ntsha ntawm cov pab pawg thib ob yog pub dawb cov plahaum roj.

Thaum cov neeg nyiam hnia, lawv ib leeg poob 6.4 kcal ib feeb, tab sis tib lub sijhawm lawv sib pauv yuav luag 300 ntau hom kab sib txawv.

Cov tib neeg uas tau noj tshais ua ntu zus feem ntau yog cov muaj rog.

Tib neeg cov ntshav "khiav" los ntawm cov hlab ntsha hauv qab qhov siab, thiab yog tias nws txoj kev ncaj ncees tau ua txhaum, nws tuaj yeem tua txog 10 meters.

Qhov nruab nrab lub neej ntawm cov laug yog tsawg dua ntawm txoj cai.

Hauv tebchaws Askiv, muaj txoj cai lij choj raws li uas tus kws phais neeg tuaj yeem tsis kam ua haujlwm rau tus neeg mob yog tias nws haus luam yeeb lossis rog dhau. Ib tus neeg yuav tsum tso tawm tus cwj pwm tsis zoo, thiab tom qab ntawd, tej zaum, nws yuav tsis xav tau kev phais mob.

Qhov hnyav ntawm tib neeg lub hlwb yog li 2% ntawm tag nrho lub cev qhov hnyav, tab sis nws noj txog 20% ​​ntawm cov pa mus rau hauv cov ntshav. Qhov tseeb no ua rau tib neeg lub hlwb muaj kev tiv thaiv rau kev puas tsuaj los ntawm cov pa oxygen.

Cov roj ntses tau paub txog ntau xyoo lawm, thiab lub sijhawm no nws tau muaj pov thawj tias nws pab daws kev mob, txo kev mob sib koom tes, txhim kho sos.

Kev noj tshuaj thiab kev tswj hwm ntawm Gliformin

Raws li txoj cai, tus kws kho mob tau tsim cov koob tshuaj Glyformin ua ib leeg zuj zus, raws li theem ntawm cov piam thaj hauv cov ntshav.

Kev kho mob feem ntau pib nrog kev siv 0.5-1 g ib hnub. Ua raws li theem ntawm glycemia, cov koob tshuaj tuaj yeem pib nce ntxiv tom qab 10-15 hnub.

Kev saib xyuas kev noj tshuaj txhua hnub yog 1-2 ntsiav tshuaj ntawm Gliformin 1000, uas tau pom zoo kom muab faib ua ob peb zaug, uas tuaj yeem txo qhov hnyav ntawm cov kev mob tshwm sim cuam tshuam nrog kem plab.

Qhov siab tshaj plaws uas tau tso cai nyob rau txhua hnub yog 3 ntsiav tshuaj ntawm Gliformin 1000, txawm li cas los xij, nws raug pom zoo tias cov neeg laus noj tsis ntau tshaj 1 g ntawm cov tshuaj.

Nrog rau kev noj tshuaj ntau dhau ntawm Gliformin, cov kab mob lactic acid tuaj yeem tsim nrog lub txiaj ntsig kev tuag, cov tsos mob thaum ntxov ua rau xeev siab, qis dua lub cev kub, qhov tsis muaj zog ntau yam, zawv plab, ntuav, mob hauv lub plab thiab cov leeg, bradyarrhythmia, txo cov ntshav siab, kiv taub hau, tsis hnov ​​qab, ua tsis taus pa thiab kev loj hlob ntawm coma Cov.

Cov lus thiab cov xwm txheej ntawm kev cia

Gliformin belongs rau ntau cov tshuaj tiv thaiv hypoglycemic (sau B) nrog cov lus pom zoo txee lub neej nyob rau hauv kev mob cia (ntawm qhov kub txog 25 ° C):

• Nrog cov ntsiab lus ntawm 250 mg thiab 500 mg ntawm cov tshuaj nquag - 3 xyoos,
• Nrog cov ntsiab lus ntawm 850 mg thiab 1000 mg ntawm cov tshuaj nquag - 2 xyoos.

Cov lus qhia rau kev siv ntsiav tshuaj

Kev qhia rau kev siv tshuaj yog hom 2 mob ntshav qab zib mellitus, thaum kev noj zaub mov nruj thiab sulfonylurea pawg tshuaj tsis muaj cov nyhuv xav tau. Glyformin tseem ua rau kev mob ntshav qab zib hom 1 ua qhov txuas rau cov tshuaj insulin.

Lub sijhawm kho mob, kev ua haujlwm ntawm lub raum yuav tsum tau saib xyuas, tsawg kawg txhua 6 lub hlis nws raug nquahu kom soj ntsuam los txiav txim rau lactate hauv cov ntshav ntshav.

Cov ntsiav tshuaj tuaj yeem ua qaug dej tau thaum noj mov lossis tom qab noj mov, qhov ntau npaum li cas yuav tsum tau sau tseg ib leeg los ntawm tus kws kho mob uas koom nrog, suav txog qhov tshwm sim ntsuas ntshav qab zib:

• thaum pib ntawm txoj kev kho, qhov tshuaj tsis ntau tshaj 1 gram ib hnub,
• tom qab 15 hnub, cov nyiaj ntawm cov nyiaj tau nce.

Tus txheej txheem kev saib xyuas cov tshuaj yuav tsum tsis pub ntau tshaj 2 gram nyob rau ib hnub, nws yuav tsum tau faib kom zoo ib yam li ntau ntau zaug. Cov neeg mob ntshav qab zib ntawm kev muaj hnub nyoog siab ib hnub raug pom zoo kom noj ntau tshaj 1 gram ntawm cov tshuaj.

Yog tias tus kws kho mob tau sau ntawv rau Gliformin rau cov ntshav qab zib, tus neeg mob yuav tsum paub tias cov ntsiav tshuaj tuaj yeem ua rau ntau yam kev tsis zoo ntawm lub cev. Ntawm ib feem ntawm cov kab mob endocrine, kev mob ntshav qab zib ntshav nce siab, nyob rau ntawm ib feem ntawm cov ntshav kev, ntshav khov yog qhov ua tau, nyob rau ntawm ib feem ntawm cov metabolism metabolism tsis muaj tshwm sim. Lub cev qee zaum ua rau cov tshuaj tsis haum nrog kev fab tshuaj:

Los ntawm cov plab hnyuv plab hnyuv plab zom mov muaj qhov ua txhaum ntawm lub qab los noj mov, raws plab, ntuav, ib qho xim hlau hauv qhov ncauj.

Yog tias muaj qhov tsis zoo tshwm sim, nws yog qhov qhia kom tsis kam kho nrog Gliformin, sab laj nrog kws kho mob.

Cov tshuaj Glyformin (nws cov lus qhia muaj kev ywj pheej muaj nyob hauv Is Taws Nem) tuaj yeem siv rau kev ua kom lub raum tsis ua haujlwm, tab sis tsuas yog thaum tsis muaj kev cia siab rau qhov nce ntawm lactic acidosis. Hauv qhov no, lub raum kev ua haujlwm yog ib txwm kuaj xyuas (tsawg kawg ib zaug txhua 3-6 lub hlis), thaum creatinine tshem tawm txo qis mus rau theem ntawm 45 ml / min, kev kho mob yog nres tam sim ntawd.

Yog tias lub raum kev ua haujlwm raug txo qis hauv kev mob ntshav qab zib siab, kev noj cov tshuaj metformin yuav tsum tau kho.

Cov tshuaj tiv thaiv tsis zoo, sib cuam tshuam nrog tshuaj

Gliformin yuav tsum tsis txhob siv rau ketoacidosis, mob siab rau mob ntshav qab zib, mob ntshav qab zib tsis ua hauj lwm, lub siab ntsws, mob ntsws tsis ua hauj lwm, thaum cev xeeb tub, pub niam mis, myocardial infarction, ntau rhiab heev rau lub Cheebtsam ntawm cov tshuaj.

Tshaj tawm kom zoo siv tshuaj kho rau cov kab mob ntawm kev kis tus kab mob sib kis, ua ntej ua txoj kev kho mob hnyav.

Qhov ua tau zoo ntawm cov tshuaj tuaj yeem txo qis nrog kev kho mob sib luag:

• glucocorticosteroid tshuaj
• cov thyroid hormones
• tshuaj kho mob
• nicotinic acid
• thaum noj qhov ncauj tawm.

Yog tias cov tshuaj metformin siv ua ke nrog insulin, sulfonylurea derivatives, tshuaj tsis muaj tshuaj tiv thaiv kab mob, nrog rau beta-blockers, muaj qhov pheej hmoo ntawm nws cov nyhuv nce ntxiv.

Gliformin Prolong

Hauv qee kis, tus neeg mob ntshav qab zib tau qhia Gliformin ntev ntev - Gliformin ntev. Nws yog ntsuas qhov ncauj nrog qhov dej txaus. Lub cuab yeej tuaj yeem pab tau nws tus kheej lossis yog ib feem ntawm kev sib xyaw ua ke.

Yog tias cov ntshav qab zib tsis tau noj cov tshuaj metformin yav dhau los, nws raug nquahu kom pib txhaj tshuaj li 750 mg ib hnub ib zaug. Tom qab 2 lub lis piam, kws kho mob yuav hloov kho qhov tshuaj (noj 2 ntsiav tshuaj ntawm 750 mg), raws li cov txiaj ntsig kev soj ntsuam qab zib. Nrog rau qhov nce ntxiv ntawm cov tshuaj tsawg kawg, muaj qhov txo qis cov tshuaj tiv thaiv tsis zoo los ntawm qhov kev zom zaub mov, tshwj xeeb, kev mob ntshav qab zib ploj mus.

Thaum kev pom zoo koob tshuaj tsis pub ua tiav qhov kev tswj hwm ntawm qib glycemia, nws yog qhov tsim nyog los noj ntau tshaj plaws ntawm cov tshuaj - 3 ntsiav tshuaj ntawm 750 mg Prolong ib hnub ib zaug.

Tus mob ntshav qab zib uas noj cov tshuaj metformin ua ib hom tshuaj uas muaj tso tawm tshuaj:

1. haus Prolong nyob rau hauv ib qho kev sib npaug ntau npaum,
2. yog tias lawv noj ntau dua 2000 mg, kev hloov pauv mus rau lub sijhawm ntev ntawm cov tshuaj tsis yog kws kho.

Yuav kom ua tau siab tshaj plaws ntawm glycemic tswj, metformin thiab cov tshuaj insulin yog siv los ua kev kho ua ke. Ua ntej, noj cov qauv tshuaj ntawm cov tshuaj (1 ntsiav tshuaj 750 mg) thaum noj hmo, thiab tus nqi ntawm cov tshuaj insulin yuav tsum tau xaiv ib tus zuj zus, raws li cov piam thaj hauv ntshav.

Qhov siab tshaj plaws nyob rau ib hnub, nws raug tso cai kom tsis pub ntau tshaj 2250 mg ntawm cov tshuaj, cov kws kho mob tshuaj xyuas tau qhia tias, muab cov xwm txheej ntawm lub cev raug tswj tau zoo, nws muaj peev xwm hloov mus rau kev noj tshuaj nrog rau kev tso tawm ib txwm muaj ntawm metformin hauv ib koob tshuaj ntawm 3000 mg.

Nws tshwm sim uas tus neeg mob tsis nco qab noj tshuaj, nyob rau hauv rooj plaub no nws tau pom tias yuav noj cov ntsiav tshuaj tom ntej ntawm cov tshuaj hauv lub sijhawm ib txwm. Koj tsis tuaj yeem noj ob zaug tshuaj metformin, qhov no yuav ua rau kev txhim kho ntawm qhov tsis zoo sab tshwm sim, dhau ntawm cov tsos mob ntshav qab zib, uas yuav tsum tsis txhob tso cai.

Glyformin Prolong yuav tsum noj txhua hnub, zam kev so.

Tus neeg mob yuav tsum qhia rau tus kws kho mob uas tuaj kawm txog kev txiav tu, kho nws lub tswv yim.

Cov qauv ntsuas, tshuaj xyuas ntawm kws kho mob

Vim tias muaj cov tshuaj contraindications, cov tshuaj tsis haum rau ntau tus neeg mob, hauv qhov no muaj qhov yuav tsum tau xaiv cov tshuaj analogues ntawm cov tshuaj, lawv tseem muaj qhov sib txawv ntawm cov tshuaj nquag (250, 500, 850, 1000). Gliformin tuaj yeem ua ke nrog cov tshuaj:

Cov neeg mob ntshav qab zib uas twb tau noj tshuaj Gliformin kho mob qhia tau tias muaj feem ntau yuav ua rau muaj kev noj ntau dhau. Feem ntau, qhov no yog vim kev siv tshuaj tsis raug cai.

Kev noj tshuaj ntau dhau tuaj yeem ua rau kev txhim kho ntawm tus mob pathological li lactic acidosis. Nws cov kev qhia tseem ceeb: mob nqaij, ntuav, xeev siab, tsis hnov ​​qab. Thaum cov tsos mob zoo li no tshwm sim, nws raug nquahu kom tsis txhob noj cov tshuaj.

Cov kws kho mob tau hais tias cov tshuaj Gliformin daws kev mob ntshav qab zib tau zoo heev, muab tau kev pom zoo uas tau pom zoo yuav tsum nruj me ntsis. Ib qho ntxiv ntawm cov tshuaj yog tus nqi tsim nyog thiab muaj nyob hauv cov chaw muag tshuaj.

Endocrinologist ceebtoom tias txhua ntu kev kho, kev sim kab mob rau cov ntshav ubno muaj kev paub tseeb. Cov tshuaj Glyformin rau ntshav qab zib yuav tsum tsis txhob noj ua ke:

1. nrog dej cawv,
2. tshuaj uas muaj ethanol.

Hmoov tsis zoo, ntshav qab zib tau dhau los ua cov kab mob uas haum, thiab ntawm cov neeg hluas. Txog kev kho, nws yog ib qho tsim nyog los sau tshuaj uas yuav pab kom ib txwm muaj qib glycemia, ib yam ntawm cov tshuaj no yog Gliformin. Yog tias cov lus qhia rau kev siv tau ua raws nraim, cov nyhuv ntawm cov tshuaj tshwm sim hauv lub sijhawm luv.

Cov ntaub ntawv hais txog cov tshuaj ua kom muaj suab thaj muaj nyob hauv cov yeeb yaj kiab hauv tsab xov xwm no.

Cov lus thiab cov xwm txheej ntawm kev cia

Gliformin yog cov tshuaj kws kho mob xaj.

Nws yuav tsum muab cia rau hauv qhov chaw qhuav, nkag tsis tau rau kev nkag mus ntawm lub hnub ci, qhov kub ntawm siab txog 25 ºС. Nrog rau kev khaws cia kom zoo, lub txee lub neej ntawm 500 mg ntsiav tshuaj yog 3 xyoos, 850 mg ntsiav tshuaj thiab 1 gram - 2 xyoos.

Pom qhov yuam kev hauv cov ntawv nyeem? Xaiv nws thiab nias Ctrl + Enter.