Cov tshuaj ntawm cov tshuaj sanovask > Kev khomob thiab kev tiv thaiv

Cov qauv ntawm cov tshuaj sanovask qhia, hloov pauv tau los ntawm cov nyhuv ntawm lub cev, npaj muaj ib lossis ntau cov tshuaj zoo ib yam. Thaum xaiv cov lus txhais, xav txog tsis yog lawv cov nqi nkaus xwb, tab sis kuj yog lub teb chaws ntawm kev tsim khoom thiab lub koob npe ntawm cov neeg tsim khoom.

Qhia txog ntawm cov tshuaj
Sau cov analogues thiab cov nqi
Xyuas
Cov lus qhia raug rau siv

Qhia txog ntawm cov tshuaj

Sanovask - NSAIDs. Nws muaj kev ua los tiv thaiv, analgesic thiab antipyretic zoo, thiab kuj inhibits platelet tag nrho. Lub tshuab kev ua ntawm kev coj ua cuam tshuam nrog kev cuam tshuam ntawm COX kev ua si - qhov tseem ceeb enzyme ntawm cov metabolism ntawm arachidonic acid, uas yog lub caij nyoog ua ntej ntawm prostaglandins, uas ua lub luag haujlwm tseem ceeb hauv lub pathogenesis ntawm o, mob thiab kub ib ce. Qhov txo qis hauv cov ntsiab lus ntawm prostaglandins (feem ntau E 1) nyob rau hauv qhov chaw ntawm thermoregulation ua rau qhov txo qis hauv lub cev kub vim yog nthuav cov hlab ntsha ntawm daim tawv nqaij thiab nce tawm hws. Qhov kev ua kom loog no yog vim ob qho tib si nruab nrab thiab ntu kev ua haujlwm. Txo txo kev sib sau ua ke, platelet adhesion thiab thrombosis los ntawm inhibiting qhov synthesis ntawm thromboxane A 2 hauv platelets.

Txo cov neeg tuag thiab txoj kev pheej hmoo ntawm kev tsim myocardial infarction nrog tsis khov tsis khov. Ua tau zoo hauv kev tiv thaiv thawj ntawm cov kab mob ntawm cov hlab plawv system thiab hauv kev tiv thaiv kab mob thib ob ntawm myocardial infarction. Hauv kev noj tshuaj txhua txhua hnub ntawm 6 g lossis ntau dua, nws inhibits cov synthesis ntawm prothrombin hauv daim siab thiab nce sijhawm prothrombin ntau ntxiv. Kev ua ntshav plasma fibrinolytic ntau dua thiab txo qis cov ntsiab lus ntawm vitamin K-dependant coagulation yam (II, VII, IX, X). Nce hemorrhagic muaj kev cuam tshuam thaum lub sij hawm kev phais mob ntxiv, nce qhov kev pheej hmoo los ntshav thaum kho nrog anticoagulants. Tsim kho txoj kev tsis haum ntawm uric acid (cuam tshuam rau nws txoj kev thim rov qab rau hauv lub raum plab hlaus), tab sis hauv kev siab. Kev thaiv ntawm COX-1 hauv lub plab ua rau lub plab ua rau lub plab hnyuv plab prostaglandins, uas tuaj yeem ua rau lub plab zom mov thiab cov ntshav tom qab.

Tso tawm daim ntawv, ntim thiab muaj pes tsawg leeg

Cov ntsiav tshuaj yog coated nrog cov ua tiav zaj duab xis daim nyias nyias ntawm cov xim dawb lossis yuav luag xim dawb, puag ncig, biconvex, hauv ntu ntu - ib qho tseem ceeb ntawm cov xim dawb lossis yuav luag dawb xim thiab daim tawv nyias nyias.

1 tab
acetylsalicylic acid	50 mg

Tshwjxeeb: lactose monohydrate - 31.5 mg, microcrystalline cellulose - 16.3 mg, colloidal silicon dioxide - 1.7 mg, sodium carboxymethyl hmoov txhuv nplej siab - 0.5 mg.

Lub plhaub muaj pes tsawg leeg: copolymer ntawm methacrylic acid thiab ethyl acrylate 1: 1 - 3.35 mg, povidone K17 - 0.56 mg, talc - 0.75 mg, macrogol 4000 - 0.34 mg.

10 Pcs. - blister packs (3) - pob ntawv ntawm cardboard.
10 Pcs. - blister packagings (6) - pob ntawv ntawm cardboard.
10 Pcs. - blister packagings (9) - ntim cov duab los qhia.
30 pcs - Cov kaus poom polymer (1) - pob khoom los ntawm cardboard.
60 pcs. - Cov kaus poom polymer (1) - pob khoom los ntawm cardboard.

1 tab
acetylsalicylic acid	75 mg

Tshwjxeeb: lactose monohydrate - 47.25 mg, microcrystalline cellulose - 24.4 mg, colloidal silicon dioxide - 2.6 mg, sodium carboxymethyl hmoov txhuv nplej siab - 0.75 mg.

Lub plhaub muaj pes tsawg leeg: copolymer ntawm methacrylic acid thiab ethyl acrylate 1: 1 - 6.7 mg, povidone K17 - 1.12 mg, talc - 1.5 mg, macrogol 4000 - 0.68 mg.

1 tab
acetylsalicylic acid	100 mg

Tshwjxeeb: lactose monohydrate - 63 mg, microcrystalline cellulose - 32.6 mg, colloidal silicon dioxide - 3.4 mg, sodium carboxymethyl hmoov txhuv nplej siab - 1 mg.

Lub plhaub muaj pes tsawg leeg: copolymer ntawm methacrylic acid thiab ethyl acrylate 1: 1 - 10.05 mg, povidone K17 - 1.68 mg, talc - 2.25 mg, macrogol 4000 - 1.02 mg.

Pharmacological kev txiav txim

NSAIDs. Nws muaj kev ua los tiv thaiv, analgesic thiab antipyretic zoo, thiab kuj inhibits platelet tag nrho. Lub tshuab kev ua ntawm kev coj ua cuam tshuam nrog kev cuam tshuam ntawm COX kev ua si - qhov tseem ceeb enzyme ntawm cov metabolism ntawm arachidonic acid, uas yog lub caij nyoog ua ntej ntawm prostaglandins, uas ua lub luag haujlwm tseem ceeb hauv lub pathogenesis ntawm o, mob thiab kub ib ce. Qhov txo qis hauv cov ntsiab lus ntawm prostaglandins (feem ntau E 1) nyob rau hauv qhov chaw ntawm thermoregulation ua rau qhov txo qis hauv lub cev kub vim yog nthuav cov hlab ntsha ntawm daim tawv nqaij thiab nce tawm hws. Qhov kev ua kom loog no yog vim ob qho tib si nruab nrab thiab ntu kev ua haujlwm. Txo txo kev sib sau ua ke, platelet adhesion thiab thrombosis los ntawm inhibiting qhov synthesis ntawm thromboxane A 2 hauv platelets.

Cov Tshuaj Pharmacokinetics

Thaum noj ntawm qhov ncauj, nws nrawm nrawm los ntawm qhov ze ntawm txoj hnyuv thiab kom qis qis los ntawm lub plab. Qhov muaj cov zaub mov hauv plab hloov pauv qhov kev nqus ntawm acetylsalicylic acid.

Nws yog metabolized hauv daim siab los ntawm hydrolysis nrog kev tsim cov salicylic acid, ua raws li kev txuas nrog glycine lossis glucuronide. Qhov concentration ntawm salicylates hauv cov ntshav ntshav kuj sib txawv thiab.

Li ntawm 80% ntawm salicylic acid khi rau cov ntshav plasma protein. Salicylates nkag mus yooj yim rau ntau cov ntaub so ntswg thiab lub cev ntawm lub cev, suav nrog nyob rau hauv cov cerebrospinal, peritoneal thiab synovial kua. Hauv qee qhov me me, cov tshuaj salicylates muaj nyob hauv cov ntaub so ntswg ntawm lub hlwb, kab - hauv bile, hws, feces. Nws nkag mus los ntawm thaj chaw muaj teeb meem me me, hauv cov khoom me me uas tawm hauv niam cov kua mis.

Hauv cov menyuam mos yug tshiab, salicylates tuaj yeem txav bilirubin los ntawm kev koom nrog albumin thiab pab txhawb kev loj hlob ntawm bilirubin encephalopathy.

Kev nkag mus rau hauv cov kab noj hniav sib koom tes yog nrawm hauv qhov muaj hyperemia thiab edema thiab maj mam nyob rau hauv qhov xwm txheej loj ntawm qhov mob o.

Thaum acidosis tshwm sim, feem ntau ntawm cov salicylate hloov dua siab tshiab rau cov tsis-ionized acid, uas nkag mus rau hauv cov ntaub so ntswg zoo, nrog rau mus rau lub hlwb.

Nws yog tsuas yog tshwj xeeb los ntawm kev ua kom muaj kev zais cia rau hauv cov tubules ntawm ob lub raum tsis hloov (60%) thiab hauv daim ntawv ntawm metabolites. Kev txiav tawm cov salicylate tsis hloov pauv nyob ntawm lub pH ntawm cov zis (nrog rau kev tso zis ntau dhau, ionization ntawm salicylates nce, lawv cov kev ua kom rov muaj mob loj dua, thiab qhov kev nthuav tawm nce ntxiv). T 1/2 acetylsalicylic acid yog kwv yees li 15 feeb. T 1/2 salicylate thaum noj tsawg kawg yog 2-3 teev, nrog ntau dua qhov ntxiv nws tuaj yeem nce ntxiv txog 15-30 teev. Hauv cov menyuam yug tshiab, kev txiav salicylate ntau qeeb dua li cov neeg laus.

Tshuaj los qhia

Rheumatism, mob rheumatoid, mob sib kis thiab ua xua myocarditis, kub taub hau rau cov mob sib kis thiab mob, mob sib khuav mus rau mob hnyav ntawm ntau yam chiv keeb (suav nrog neuralgia, mob myalgia, mob taub hau), kev tiv thaiv ntawm thrombosis thiab embolism, tiv thaiv thawj thiab lwm yam ntawm myocardial infarction , tiv thaiv kom tsis txhob muaj kab mob cerebrovascular raws li hom ischemic.

Hauv kev txhaj tshuaj tiv thaiv kab mob thiab kev ua xua: ua ntau zuj zus koob tshuaj rau "aspirin" desensitization thiab tsim kev tso siab ruaj khov rau NSAIDs rau cov neeg mob "aspirin" hawb pob thiab "aspirin triad".

ICD-10 cov lis dej num

ICD-10 code	Kev taw qhia
I21	Mob myocardial infarction
I40	Mob myocarditis
I63	Cerebral infarction
I74	Embolism thiab leeg ntshav thrombosis
I82	Embolism thiab thrombosis ntawm lwm cov leeg ntshav
M05	Seropositive Rheumatoid Mob Qog
M79.1	Neej Hmoob
M79.2	Tsis paub tseeb neuralgia thiab neuritis
R50	Cov quav tsis tau kub
R51	Mob taub hau
R52.0	Ntse mob
R52.2	Lwm qhov mob (mob ntev)

Sab sij huam

Los ntawm lub plab zom mov: xeev ntuav, ntuav, tsis xav noj mov, mob epigastric, raws plab, tsis tshua muaj - kev tshwm sim ntawm qhov nqaij tawv thiab mob txhab, los ntshav los ntawm txoj hnyuv, ua kom lub siab ua haujlwm tsis zoo.

Los ntawm ib sab ntawm lub hauv nruab nrab ntawm cov hlab ntsha: nrog rau siv ntev, kiv taub hau, mob taub hau, rov tuaj yeem pom qhov muag tsis pom kev, tsis nco qab, aseptic meningitis yog ua tau.

Los ntawm cov kab mob hemopoietic: tsis tshua muaj - thrombocytopenia, ntshav liab.

Los ntawm cov ntshav kev coagulation system: tsis tshua muaj - hemorrhagic mob, ntev ntev ntawm los ntshav lub sijhawm.

Los ntawm cov kab mob txeeb zis: tsis tshua muaj - hnov mob raum muaj nuj nqi, nrog lub sijhawm siv ntev - mob raum tsis ua haujlwm, tus mob nephrotic.

Kev tsis haum tshuaj: tsis tshua muaj - ua pob khaus rau ntawm daim tawv nqaij, Quincke's edema, bronchospasm, "aspirin triad" (ua ke ntawm bronchial hawb pob, ua mob polyposis ntawm lub qhov ntswg thiab txhaws ntswg thiab ua paug rau acetylsalicylic acid thiab pyrazolone tshuaj).

Lwm yam: hauv qee kis - Reye's syndrome, nrog rau siv ntev - nce cov tsos mob ntawm lub plawv tsis ua haujlwm ntev.

Cev xeeb tub thiab lactation

Contraindicated nyob rau hauv I thiab III trimesters ntawm cev xeeb tub. Hauv lub sijhawm thib ob ntawm kev xeeb tub, kev nkag mus ib zaug muaj peev xwm ua tau raws li cov cim nruj me ntsis.

Nws muaj cov teebmeem teratogenic: thaum siv thawj peb lub hlis, nws ua rau kev txhim kho ntawm kev txhav ntawm lub sab qaum, hauv peb lub hlis nws ua rau inhibition ntawm kev ua haujlwm (inhibition ntawm prostaglandin synthesis), ua ntej kaw ntawm ductus arteriosus hauv lub plab, mob ntsws ntsig txog ntshav thiab mob ntshav hauv lub ntsws.

Acetylsalicylic acid yog tawm hauv cov kua mis, uas ua rau muaj kev pheej hmoo los ntshav hauv tus menyuam vim tias lub plawv tsis ua haujlwm, yog li leej niam yuav tsum tsis txhob siv tshuaj acetylsalicylic acid thaum lactation.

Cov lus qhia tshwj xeeb

Nws yog siv nrog ceev faj hauv cov neeg mob uas muaj kab mob rau daim siab thiab lub raum, nrog mob ntsws asthma, mob tawm tsam thiab mob txhab thiab mob ntshav los ntawm txoj hnyuv hauv cov hlab ntsha, nrog ntau dua los ntshav lossis nrog kev kho mob ua ke, decompensated mob plawv tsis ua haujlwm.

Acetylsalicylic acid txawm hais tias hauv kev txhaj tshuaj me me txo cov kev tsis haum ntawm uric acid los ntawm lub cev, uas tuaj yeem ua rau muaj mob hnyav gout hauv cov neeg mob yooj yim. Thaum lub sij hawm ntev txoj kev kho thiab / lossis kev siv tshuaj acetylsalicylic acid nyob rau hauv cov koob tshuaj siab, kev saib xyuas kev kho mob thiab kev soj ntsuam hemoglobin ntau ntau yuav tsum ua.

Kev siv cov tshuaj acetylsalicylic acid ua cov tshuaj tiv thaiv kab mob hauv ib koob tshuaj 5-8 g txhua hnub vim muaj ntau qhov tshwm sim ntawm kev phiv los ntawm txoj hnyuv.

Ua ntej kev phais mob, txhawm rau kom los ntshav thaum phais thiab tom qab lub sijhawm txiav, koj yuav tsum tsis txhob noj salicylates li 5-7 hnub.

Thaum lub sij hawm kho ntev, kev kuaj ntshav dav dav thiab fecal occult blood test yuav tsum ua.

Kev siv cov tshuaj acetylsalicylic acid hauv kev kho cov me nyuam yog contraindicated, txij li thaum kis tus kab mob kis rau cov menyuam yaus hauv qab ntawm acetylsalicylic acid, txoj kev pheej hmoo ntawm kev tsim muaj tus mob Reye tus mob nce ntxiv. Cov tsos mob ntawm Tus Mob Reye cov tsos mob suav nrog mob ntuav ntev, mob encephalopathy, thiab ua rau daim siab.

Lub sijhawm ntawm kev kho mob (tsis tau sab laj nrog kws kho mob) yuav tsum tsis pub ntau tshaj 7 hnub thaum tshuaj kho mob ua kom loog thiab ntau dua 3 hnub ua ib qho tshuaj tiv thaiv kab mob.

Thaum mus khomob, tus neeg mob yuav tsum yauv tsum tsis haus cawv.

Yeeb tshuaj sib cuam tshuam

Nrog rau kev siv sib xyaw ua ke ntawm cov tshuaj antacids uas muaj cov tshuaj magnesium thiab / lossis aluminium hydroxide, maj mam thiab txo qhov nqus ntawm acetylsalicylic acid.

Nrog rau kev siv calcium calcium blockers ib txhij, tshuaj uas txwv tsis pub kom muaj calcium los yog nce ntxiv cov tshuaj calcium los ntawm lub cev, qhov kev pheej hmoo los ntshav ntau dua.

Nrog rau kev siv ua ke nrog cov acetylsalicylic acid, cov nyhuv ntawm heparin thiab indirect anticoagulants, hypoglycemic cov neeg sawv cev ntawm sulfonylureas, insulin, methotrexate, phenytoin, valproic acid yog kho kom zoo.

Nrog rau kev siv ua ke nrog corticosteroids, kev pheej hmoo ntawm kev ua kiav txhab thiab kev tshwm sim ntawm lub plab zom mov nce ntxiv.

Nrog rau kev siv ua ke, cov hauj lwm zoo ntawm diuretics (spironolactone, furosemide) raug txo qis.

Nrog rau siv ua ke nrog lwm cov NSAIDs, kev pheej hmoo ntawm cov mob tshwm sim tuaj. Acetylsalicylic acid tuaj yeem txo cov ntshav plasma ntau ntawm indomethacin, piroxicam.

Thaum siv ib txhij nrog kub npaj, acetylsalicylic acid tuaj yeem ua rau daim siab puas.

Nrog rau kev siv thooj txhij, cov hauj lwm zoo ntawm uricosuric cov neeg sawv cev txo qis (suav nrog probenecid, sulfinpyrazone, benzbromarone).

Nrog rau kev siv acetylsalicylic acid thiab sodium alendronate tib lub sijhawm, kev txhim kho ntawm txoj hlab pas loj heev yog ua tau.

Nrog rau kev siv sib txig nrog griseofulvin, ib qho kev ua txhaum ntawm kev nqus ntawm acetylsalicylic acid yog ua tau.

Ib qhov teeb meem ntawm qhov tshwm sim ntawm iris hemorrhage tau piav qhia thaum noj ib qho txiaj ntsig ntawm ginkgo biloba tiv thaiv keeb kwm ntawm kev siv lub cev ntev ntawm acetylsalicylic acid ntawm ib koob ntawm 325 mg / hnub. Nws ntseeg tau tias qhov no yuav yog vim muaj cov roj ntsha tiv thaiv kab mob ntxiv rau platelet aggregation.

Nrog rau kev siv dipyridamole tib lub sijhawm, kev nce C kom ntau ntawm salicylate hauv ntshav ntshav thiab AUC yog ua tau.

Nrog rau kev siv ua ke nrog acetylsalicylic acid, ntau ntawm digoxin, barbiturates thiab cov roj ntsha lithium hauv cov ntshav ntshav nce ntxiv.

Nrog rau kev sib xyaw ua ke ntawm cov tshuaj salicylates nyob rau hauv cov koob tshuaj ntau nrog carbonic anhydrase inhibitors, salicylate intoxication yog ua tau.

Acetylsalicylic acid ntawm koob tshuaj tsawg dua 300 mg / hnub muaj qhov tsis zoo ntawm cov txiaj ntsig ntawm captopril thiab enalapril. Thaum siv cov tshuaj acetylsalicylic acid nyob rau hauv cov koob tshuaj siab, qhov txo qis hauv kev ua tau ntawm captopril thiab enalapril yog ua tau.

Nrog rau kev siv ua ke ntawm kev ua noj ua caffeine ua rau nce tus nqi nqus, ntshav concentration thiab bioavailability ntawm acetylsalicylic acid.

Nrog rau kev siv metoprolol ib txhij tuaj yeem nce C max salicylate hauv ntshav ntshav.

Thaum siv pentazocine tiv thaiv keeb kwm yav dhau los ntawm kev siv lub sijhawm ntev ntawm acetylsalicylic acid nyob rau hauv cov koob tshuaj siab, muaj kev pheej hmoo ntawm kev phiv tshuaj ntau los ntawm lub raum.

Nrog tib lub sijhawm siv phenylbutazone txo uricosuria tshwm sim los ntawm acetylsalicylic acid.

Nrog rau kev siv ethanol thooj txhij tuaj yeem txhim kho cov nyhuv ntawm acetylsalicylic acid ntawm lub plab zom mov.

Nosological kev faib tawm (ICD-10)

Enteric Txheej Txheej	1 tab.
yam tshuaj:
acetylsalicylic acid	50/75/100 mg
excipients (tseem ceeb): lactose monohydrate - 31.5 / 47.25 / 63 mg, MCC - 16.30 / 24.4 / 32.6 mg, colloidal silicon dioxide - 1.7 / 2.6 / 3.4 mg, sodium carboxymethyl hmoov txhuv nplej siab - 0 5 / 0.75 / 1 mg
zaj duab xis sheath: ib lub copolymer ntawm methacrylic acid thiab ethyl acrylate (1: 1) - 3.35 / 6.7 / 10.05 mg, povidone K17 - 0.56 / 1.12 / 1.68 mg, talc - 0.75 / 1.5 / 2.25 mg, macrogol 4000 - 0.34 / 0.68 / 1.02 mg

Cov Tshuaj Hauv Tshuaj

Lub tshuab nruab nrab ntawm kev ua ntawm acetylsalicylic acid (ASA) yog ua raws li cov dej tsis haum ntawm COX-1, vim qhov kev coj ua ntawm PG, prostacyclins thiab Tx yog txhaws. Txo cov kev sib sau ua ke, platelet adhesion, thiab thrombosis los ntawm kev ua kom dhau los ntawm TxA2 synthesis hauv platelets. Nws tsub kom cov kev ua haujlwm ntawm fibrinolytic ntawm cov ntshav ntshav thiab txo qhov kev cia siab ntawm cov vitamin K-dependant coagulation yam (II, VII, IX, X). Cov nyhuv antiplatelet yog feem ntau hais rau hauv platelets, vim hais tias lawv tsis tuaj yeem rov coj los ua ke COX. Qhov txiaj ntsig antiplatelet tshwm sim tom qab siv cov koob tshuaj me me ntawm cov tshuaj thiab mob siab rau 7 hnub tom qab siv ib zaug. Cov peev txheej ntawm ASA no tau siv rau hauv kev tiv thaiv thiab kho myocardial infarction, mob plawv, mob ntshav tawm ntawm cov leeg ntshav. ASA kuj tseem muaj cov tshuaj tiv thaiv kev tiv thaiv, ua kom loog, tiv thaiv kom ua paug.

Cov Yuav Tsum Muaj

cov tshuaj tiv thaiv tsis haum rau acetylsalicylic acid, cov neeg tsis paub nyob hauv cov tshuaj thiab lwm yam tshuaj NSAIDs,

erosive thiab ulcerative lesions ntawm lub plab zom plab (hauv qhov mob loj),

bronchial hawb pob los ntawm kev noj salicylates thiab lwm cov NSAIDs,

kev sib xyaw ua ke ntawm bronchial hawb pob, kev mob siab ntsws ntau ntawm lub qhov ntswg thiab qhov ntswg txhaws ntswg thiab tsis haum rau ASA,

ua ke siv nrog methotrexate hauv ib koob tshuaj 15 mg / vas thiv lossis ntau dua,

mob raum tsis ua haujlwm (Cl creatinine tsawg dua 30 ml / min),

mob rau daim siab ua hauj lwm loj (qib B thiab siab tshaj nyob ntawm Child-Pugh nplai),

mob ntsws raum tsis txaus III - IV ua haujlwm tau raws li kev faib tawm NYHA,

lactose intolerance, lactase deficiency, qabzib / galactose malabsorption syndrome (cov tshuaj muaj lactose monohydrate),

cev xeeb tub (I thiab III trimesters),

lub sij hawm pub niam mis,

hnub nyoog txog 18 xyoo.

Nrog saib xyuas: gout, hyperuricemia, mob rwj plab thiab duodenal mob los yog keeb kwm ntawm lub plab zom mov ntshav (lub raum tsis ua haujlwm), lub raum tsis ua haujlwm (creatinine Cl ntau dua 30 ml / min), CVD cuam tshuam (suav nrog mob plawv tsis ua haujlwm, hypovolemia, mob phais mob hnyav) kev cuam tshuam, sepsis lossis mob ntshav ntau - muaj kev pheej hmoo ntawm lub raum tsis ua haujlwm thiab mob raum tsis ua haujlwm), mob siab rau lub siab (qis dua qib B ntawm qhov ntsuas me nyuam-Pugh), mob ntsws asthma, mob ntsws ua haujlwm ntev. kev ua pa tawm, quav nyab kub taub hau, lub qhov ntswg polyposis, kev fab tshuaj, nrog rau NSAIDs, analgesics, anti-inflammatory, antirheumatic cov neeg sawv cev, cov ntshav qabzib ntau-6-phosphate dehydrogenase tsis txaus (ASA tuaj yeem ua rau hemolysis thiab hemolytic anemia, yam tseem ceeb tuaj yeem ua rau muaj kev phom sij ntau dua ntawm cov tshuaj, kub ib ce thiab mob hnyav), cev xeeb tub (II lub sijhawm plaub hlis), kev thov kho kev phais mob (suav nrog cov menyuam yaus me, piv txwv li, rho tawm hniav), ib txhij tswj hwm nrog methotrexate hauv ib koob tshuaj tsawg dua 15 mg / vas thiv, anticoagulants, thrombolytic lossis antiplatelet agents thiab txhais tau tias, narcotics yuav muab thiab salicylic acid derivatives rau hauv high school koob, digoxin, hypoglycemic agents rau qhov ncauj siv (sulfonylurea derivatives) thiab insulin, valproic acid, haus dej cawv (tshwj xeeb yog haus dej haus cawv), SSRIs, ibuprofen (cm. "Sis").

Sab sij huam

Los ntawm lub plab zom mov: feem ntau - xeev siab, kub siab, ntuav, mob hauv plab, tsis tshua muaj - mob plab thiab duodenal mob, tsis tshua muaj tshwm sim - perforated mob ntawm lub plab thiab duodenal mucosa, mob plab hnyuv los ntshav, hloov kho mob hepatic nrog kev ua si ntawm hepatic transaminases.

Los ntawm sab hauv lub hauv nruab nrab ntawm cov hlab hlwb: kiv taub hau, hnov pob ntseg, tinnitus, uas tej zaum yuav yog tus tsos mob ntawm kev haus tshuaj ntau dhau (saib "Kev Tsaus Siab").

Los ntawm cov kab ke hemopoietic: nce ntxiv ntawm qhov pauj perioperative (intra- thiab postoperative) los ntshav, hematomas (bruises), ntswg ntswg, ntshav tawm hauv cov pos hniav, los ntshav los ntawm cov hlab ntshav tawm. Muaj cov ntaub ntawv qhia txog kev muaj mob ntshav los ntshav ntau, nrog rau txoj hnyuv los ntshav thiab mob ntshav tawm ntawm lub cev (tshwj xeeb tshaj yog cov neeg mob ntshav tsis tau nce lub hom phiaj ntshav siab thiab / lossis tau txais kev kho mob nrog cov tshuaj anticoagulant), uas qee qhov tuaj yeem ua rau muaj kev phom sij rau lub neej. Cov. Kev los ntshav tuaj yeem ua rau muaj kev puas siab ntsws lossis mob ntshav qab zib posthemorrhagic / hlau tsis muaj ntshav txaus (piv txwv, vim ntshav tawm) muaj qhov sib luag hauv tsev kho mob thiab kuaj mob (asthenia, pallor, hypoperfusion). Muaj cov ntaub ntawv tshaj tawm ntawm cov neeg muaj mob hemolysis thiab hemolytic anemia rau cov neeg mob uas muaj ntshav qabzib ntau-6-phosphate dehydrogenase tsis txaus.

Kev tsis haum tshuaj: daim tawv nqaij ua pob khaus, khaus, urticaria, Quincke's edema, rhinitis, o ntawm cov qog ua pa ntawm lub qhov ntswg, bronchospasm, cardiorespiratory kev nyuaj siab mob, nrog rau muaj kev tsis haum, suav nrog kev poob siab anaphylactic.

Los ntawm cov kab mob urinary: muaj cov ntaub ntawv hais txog kev muaj mob raum thiab tsis ua mob rau lub raum.

Kev sib txuam

Nrog rau kev siv ASA ib txhij txhim kho cov nyhuv ntawm cov tshuaj uas teev hauv qab no. Yog tias tsim nyog, tib lub sijhawm teem ntawm ASA nrog rau cov nyiaj tau teev tseg yuav tsum xav txog qhov yuav tsum tau txo lawv cov koob tshuaj:

- methotrexate - vim yog kev txo qis hauv kev ua haujlwm ntawm lub raum thiab nws hloov chaw los ntawm kev sib txuas lus nrog cov protein,

- anticoagulants, thrombolytic thiab antiplatelet agents (ticlopidine) - muaj kev pheej hmoo ntawm los ntshav vim yog qhov tshwm sim los ntawm kev sib txuam ntawm cov kev kho mob tseem ceeb ntawm cov tshuaj uas siv,

- cov tshuaj nrog anticoagulant, thrombolytic los yog antiplatelet effect, - muaj qhov nce ntawm kev puas tsuaj ntawm lub plab hnyuv mucosa,

- SSRIs - tuaj yeem ua rau muaj kev pheej hmoo los ntshav ntau ntxiv los ntawm cov mob hnyuv sab sauv (synergism nrog ASA),

- digoxin - vim tias qhov txo qis hauv nws lub raum ua rau siab tuaj yeem, uas tuaj yeem ua rau muaj kev xav ntau dhau,

- hypoglycemic cov neeg sawv cev rau kev tswj hwm ntawm qhov ncauj (sulfonylurea derivatives) thiab insulin vim muaj cov khoom hypoglycemic ntawm ASA nws tus kheej hauv kev txhaj tshuaj ntau thiab hloov ntawm sulfonylurea derivatives los ntawm lub koom haum nrog cov ntshav ntshav protein,

- valproic acid - nws lub cev muaj kuab lom vim muaj kev cuam tshuam los ntawm kev sib txuas lus nrog cov ntshav ntshav protein,

- NSAIDs thiab salicylic acid derivatives nyob rau hauv cov koob tshuaj ntau - muaj kev pheej hmoo ntawm cov nyhuv ulcerogenic thiab los ntshav los ntawm cov hnyuv ua rau muaj qhov tshwm sim ntawm kev sib txuam,

- ibuprofen - muaj kev thaiv kev tsis sib haum nrog kev tsis tuaj yeem nyob rau hauv thromboxanesynthetase vim kev ua haujlwm ntawm ASA, uas ua rau txo qis ntawm cov teebmeem ntawm cardioprotective ntawm ASA,

- ethanol - muaj kev pheej hmoo ntau ntawm kev puas tsuaj rau lub plab hnyuv plab thiab ntev ntawm lub sijhawm los ntshav los ntawm kev sib nrig sib txhim kho ntawm cov teebmeem ntawm ASA thiab ethanol.

Kev tswj hwm tib txhij ntawm ASA nyob rau hauv cov koob tshuaj siab tuaj yeem ua kom tsis muaj zog ntawm cov tshuaj uas teev rau hauv qab no. Yog tias tsim nyog, kev sib ntsib ib txhij ntawm ASA nrog cov nyiaj teev tau teev yuav tsum xav txog qhov kev xav hloov noj tshuaj:

- ib qho diuretics - muaj qhov txo GFR vim qhov txo qis hauv kev coj los ua ke ntawm GHGs hauv lub raum,

- ACE inhibitors - muaj qhov koob tshuaj txo qis hauv GFR raws li kev txiav txim siab ntawm GHGs nrog vasodilating nyhuv, ntsig txog, qhov ua kom tsis muaj zog ntawm cov nyhuv hypotensive. Kev soj ntsuam qis hauv GFR raug pom nrog kev txhaj tshuaj ASA txhua hnub ntawm ntau dua 160 mg. Tsis tas li ntawd, muaj qhov txo qis ntawm cov txiaj ntsig cardioprotective zoo ntawm ACE inhibitors tshuaj rau cov neeg mob rau kev kho mob plawv tsis ua hauj lwm. Cov nyhuv no kuj tau tshwm sim thaum siv nrog ASA hauv kev txhaj tshuaj loj,

- cov tshuaj nrog uricosuric kev ua (benzbromaron, probenecid) - qhov txo qis ntawm cov nyhuv uricosuric vim kev sib tw ntawm kev rov qab ua haujlwm ntawm lub raum tubular urinary acid excretion,

- Gic systemic (tshwj tsis yog muaj hydrocortisone siv rau kev hloov kho ntawm Addison's disease) - muaj qhov nce ntxiv ntawm qhov kev tshem tawm ntawm salicylates thiab, raws li, ua rau lawv txoj haujlwm qaug zog.

Tsuas tshuaj thiab tswj hwm

Sab hauv tsis tas yuav zom, haus dej kom ntau, zoo dua ua ntej noj mov. Cov ntsiav tshuaj tau noj 1 zaug hauv ib hnub.

Lub sijhawm kho yog txiav txim los ntawm tus kws khomob tuaj koom.

Kev tiv thaiv kab mob pob ntseg ib qho myocardial infarction thaum muaj kev pheej hmoo. 50-100 mg / hnub.

Kev tiv thaiv ntawm kev rov ua dua myocardial infarction, tsis khov thiab ruaj khov angina pectoris. 50-100 mg / hnub.

Tsis khov tsis khov (nrog xav tias tsam muaj tus mob myocardial infarction). Thawj koob tshuaj ntawm 100 mg (thawj ntsiav tshuaj yuav tsum tau chewed rau kev nqus sai dua) yuav tsum tau noj los ntawm tus neeg mob sai li sai tau tom qab muaj kev xoom xaim ntawm kev txhim kho ntawm kev mob siab myocardial infarction. Hauv 30 hnub tom qab tom qab txoj kev loj hlob ntawm myocardial infarction, ib koob tshuaj ntawm 200-300 mg / hnub yuav tsum tswj hwm. Tom qab 30 hnub, txoj kev kho tsim nyog yuav tsum tau kho kom tsis txhob rov muaj tus mob myocardial infarction.

Kev tiv thaiv mob stroke thiab transserebrovascular kev huam yuaj. 75-100 mg / hnub.

Kev tiv thaiv ntawm thromboembolism tom qab kev phais mob thiab cuam tshuam cov ntshav khov ntxiv. 50-100 mg / hnub.

Kev Tiv Thaiv ntawm DVT thiab pulmonary embolism thiab nws cov ceg. 100-200 mg / hnub.

Daim ntawv noj tshuaj:

enteric-coated ntsiav tshuaj

Muaj ib ntsiav tshuaj:

acetylsalicylic acid - 50.00 mg, 75.00 mg lossis 100.00 mg.

Excipients (tub ntxhais):

lactose monohydrate - 31.50 mg, 47.25 mg lossis 63.00 mg, microcrystalline cellulose - 16.30 mg, 24.40 mg lossis 32.60 mg, colloidal silicon dioxide - 1.70 mg, 2.60 mg lossis 3.40 mg; sodium carboxymethyl hmoov txhuv nplej siab 0.50 mg, 0.75 mg lossis 1.00 mg.

Excipients (plhaub):

copolymer ntawm methacrylic acid thiab ethyl acrylate 1: 1 - 3.35 mg, 6.70 mg lossis 10.05 mg, povidone K17 - 0.56 mg, 1.12 mg lossis 1.68 mg, talc - 0.75 mg, 1 , 50 mg lossis 2.25 mg, macrogol 4000 - 0.34 mg, 0.68 mg lossis 1.02 mg.

Hloov, biconvex ntsiav tshuaj, enteric coated zaj duab xis, dawb lossis yuav luag dawb. Ntawm ntu hla: qhov tseem ceeb yog xim dawb lossis yuav luag dawb thiab ib daim nyias nyias ntawm lub plhaub.

Noj ntau dhau

Nws tuaj yeem muaj kev txhaum loj heev, tshwj xeeb yog cov neeg laus thiab menyuam yaus.

Salicylism syndrome tshwm sim thaum noj ASA ntawm ib koob ntau dua 100 mg / kg / hnub rau ntau tshaj 2 hnub vim kev siv tshuaj lom cov tshuaj ua ib feem ntawm kev siv tshuaj tsis raug cai (mob ntev ntev) lossis ib qho kev siv tshuaj lom lossis kev txhob txwm siv tshuaj lom rau cov neeg laus lossis menyuam yaus (mob lom) Cov.

Me me mus rau mob hnyav (ib koob tsawg dua 150 mg / kg)

Cov tsos mob kiv taub hau, plhaw, tsis hnov lus, tawm hws ntau, xeev siab thiab ntuav, mob taub hau, tsis meej pem, tachypnea, hyperventilation, ua pa alkalosis.

Kev Kho Mob: lub plab zom zaub mov, kev coj ua dua ntawm cov roj carbon activated, yuam alkaline diuresis, rov qab ua kom cov dej-electrolyte tshuav thiab KShchS.

Nruab nrab thiab qib hnyav (ib koob tshuaj 150-300 mg / kg - mob hnyav hnyav, ntau dua 300 mg / kg - hnyav lom)

Cov tsos mob ua pa alkalosis nrog rau kev kho mob metabolic acidosis, hyperpyrexia, hyperventilation, tsis-cardiogenic pulmonary edema, ua pa nyuaj, mob ntsws, ntawm lub cev ntawm CCC - mob plawv dhia tsis txaus, cim tau poob qis hauv ntshav siab, inhibition ntawm kev ua si rau lub plawv, ntawm cov dej-electrolyte tshuav - lub cev qhuav dej, lub plawv tsis ua hauj lwm los ntawm oliguria mus txog rau kev txhim kho lub raum tsis ua haujlwm, tus cwj pwm los ntawm hypokalemia, hypernatremia, hyponatremia, cov ntshav qabzib tsis muaj qabzib - hyperglycemia, hypoglycemia (tshwj xeeb hauv cov menyuam yaus), etoatsidoz, tinnitus, lag ntseg, hnyuv los ntshav, Hematological mob - los ntawm inhibition ntawm platelet aggregation mus rau ib tug coagulopathy, qhov yuav ncua ntxiv PX, hypoprothrombinemia, neurological mob - toxic encephalopathy thiab kev tsim txom ntawm lub hauv paus poob siab system (nkees nkees, tsis meej pem, coma, convulsions).

Kev Kho Mob: kev mus pw hauv tsev kho mob sai hauv cov chav haujlwm tshwj xeeb rau kev kho mob kub ntxhov - lub plab zom zaub mov, rov ua kom zoo dua ntawm kev sib xyaw hluav ncaig, yuam alkaline diuresis, hemodialysis, rov kho cov dej-electrolyte tshuav thiab acid-base tshuav, kev kho mob tshwm sim.

Chaw tsim tshuaj paus

Chaw tsim tshuaj paus / koom haum lees txais cov neeg siv khoom kev tsis txaus siab: OJSC Irbit Tshuaj Ua Si. 623856, Russia, Sverdlovsk cheeb tsam, Irbit, st. Kirova, 172.

Tel./fax: (34355) 3-60-90.

Chaw nyob ntau lawm: Sverdlovsk Cheeb Tsam, Irbit, ul. Karl Marx, 124-a.

Lub koom haum saib xyuas kev cai lij choj lub npe uas daim ntawv pov thawj rau npe tau muab tawm yog: OAO Aveksima 125284, Russia, Moscow, Leningradsky prospect, 31A, p. 1.

Kev ntsuas rau siv

Kev ua npaws yoov tshaj cum hauv kab mob sib kis thiab mob.

Mob leeg mob (ntawm ntau lub hauv paus pib): mob taub hau (suav nrog cov cuam tshuam nrog kev haus cawv haus cawv), mob taub hau, mob hniav, mob hlwb neuralgia, mob caj dab, mob radicular radicular syndrome, myalgia, arthralgia, algodismenorea.

Raws li kev siv tshuaj tiv thaiv kab mob (siv ntau txog 300 mg / hnub): mob plawv, muaj ntau yam kev pheej hmoo rau mob plawv, mob tsis muaj zog myocardial ischemia, tsis nco qab angina pectoris, mob myocardial infarction (los txo cov kev pheej hmoo ntawm myocardial infarction thiab kev tuag tom qab myocardial infarctionia), rov qab ua haujlwm dua yog mob hlwb. mob hlab ntsha hauv cov txiv neej, kev mob plawv hauv lub plawv (kev tiv thaiv thiab kev kho mob ntawm thromboembolism), lub pob txha caj qaum mob angioplasty thiab stent tso (txo txoj kev pheej hmoo ntawm rov mob plab thiab kev kho mob ntawm stratification ntawm txoj hlab ntshav liab), nrog atheros klerotic cov qhov txhab ntawm txoj hlab ntshav (Kawasaki kab mob), aortoarteritis (Takayasu tus kab mob), mitral valvular lub plawv tsis zoo thiab mob atrial fibrillation, mitral valve prolapse (tiv thaiv ntawm thromboembolism), mob ntsws, mob ntsws, mob ntsws, mob ntsws thim rov qab,

Mob caj dab, mob caj dab, mob caj dab-sib chwv myocarditis, pericarditis, rheumatic chorea - tsis siv tam sim no ..

Yuav siv li cas: noj ntau thiab hom tshuaj kho

Cov ntsiav tshuaj ntawm cov tshuaj tau noj ntawm qhov ncauj, nrog febrile thiab mob mob rau cov neeg laus - 0.5-1 g / hnub (txog 3 g), muab faib ua 3 koob. Lub sijhawm tiv thaiv kev kho mob yuav tsum tsis pub ntau tshaj 2 lub lis piam.

Txhawm rau txhim kho rheological zog ntawm cov ntshav - 0.15-0.25 g / hnub rau ntau lub hlis.

Cov ntsiav tshuaj uas muaj ASA nyob rau hauv cov koob tshuaj saum toj no 325 mg (400-500 mg) yog tsim los siv ua tshuaj pleev tshuaj tiv thaiv kab mob thiab tiv thaiv kab mob, hauv koob tshuaj 50-75-100-300-325 mg rau cov laus, feem ntau yog tshuaj tiv thaiv kab mob antiplatelet.

Nrog myocardial infarction, ntxiv rau kev tiv thaiv kab mob thib ob hauv cov neeg mob tom qab myocardial infarction, 40-325 mg ib hnub ib zaug (feem ntau 160 mg). Raws li ib qho inhibitor ntawm platelet kev sib sau - 300-325 mg / hnub ntev.Nrog cov kab mob cerebrovascular sib txawv txav hauv cov txiv neej, mob hlwb thomboembolism - 325 mg / hnub nrog maj mam nce mus rau qhov ntau ntawm 1 g / hnub, rau kev tiv thaiv ntawm kev rov huam dua - 125-300 mg / hnub. Rau kev tiv thaiv ntawm thrombosis lossis occlusion ntawm aortic shunt, 325 mg txhua 7 teev los ntawm kev txhaj tshuaj rau txoj hnyuv hauv plab, tom qab ntawd 325 mg rau qhov ncauj 3 zaug hauv ib hnub (feem ntau yog ua ke nrog dipyridamole, uas yog lawb tawm tom qab ib lub lim tiam, txuas ntxiv kev kho mob ntev nrog cov tshuaj).

Nrog kev mob rheumatism tau siv tshuaj (tam sim no tsis yog kws kho) nyob rau hauv ib koob tshuaj 5-8 g txhua hnub rau cov neeg laus thiab 100-125 mg / kg rau cov hluas (15-18 xyoo), qhov ntau zaus siv yog 4-5 zaug hauv ib hnub. Tom qab 1-2 lub lis piam ntawm kev kho mob, cov menyuam yaus raug txo qhov kev txhaj tshuaj mus rau 60-70 mg / kg / hnub, kev kho mob rau cov neeg laus tau txuas ntxiv hauv tib lub sijhawm, lub sijhawm kho yog txog 6 lub lis piam. Kev tshem tawm yog nqa tawm maj hauv 1-2 asthiv.

Cov lus nug, lus teb, tshuaj xyuas tshuaj Sanovask

Cov ntaub ntawv muab yog npaj rau kev kho mob thiab kws tshaj lij. Cov ntaub ntawv muaj tseeb tshaj plaws txog cov tshuaj muaj nyob hauv cov lus qhia uas txuas nrog lub ntim los ntawm cov kws tsim khoom lag luam. Tsis muaj cov ntaub ntawv tso tawm rau ntawm no lossis lwm nplooj ntawv ntawm peb lub xaib tuaj yeem hloov chaw rau qhov tsis txaus siab tus kheej rau tus kws tshaj lij.

Kev Sib Sau thiab daim ntawv ntawm kev tso tawm

Ntsiav tshuaj - 1 ntsiav tshuaj:

Cov tshuaj kom nquag pliav: acetylsalicylic acid 50 mg,
Cov neeg siv: Cov neeg tsis txaus siab: lactose monohydrate - 31.5 mg, microcrystalline cellulose - 16.3 mg, colloidal silicon dioxide - 1.7 mg, sodium carboxymethyl hmoov txhuv nplej - 0.5 mg,
lub plhaub muaj pes tsawg leeg: copolymer ntawm methacrylic acid thiab ethyl acrylate 1: 1 - 3.35 mg, povidone K17 - 0.56 mg, talc - 0.75 mg, macrogol 4000 - 0.34 mg.

30 ntsiav tshuaj ib pob.

NSAIDs. Nws muaj kev ua los tiv thaiv, analgesic thiab antipyretic zoo, thiab kuj inhibits platelet tag nrho. Lub tshuab kev ua ntawm kev coj ua cuam tshuam nrog kev cuam tshuam ntawm COX kev ua si - qhov tseem ceeb enzyme ntawm cov metabolism ntawm arachidonic acid, uas yog lub caij nyoog ua ntej ntawm prostaglandins, uas ua lub luag haujlwm tseem ceeb hauv lub pathogenesis ntawm o, mob thiab kub ib ce. Qhov kev poob qis hauv cov ntsiab lus ntawm prostaglandins (feem ntau E1) nyob rau hauv qhov chaw nruab nrab ntawm cov thermoregulation ua rau muaj qhov txo qis hauv lub cev kub vim qhov nthuav dav ntawm cov hlab ntsha ntawm daim tawv nqaij thiab nce tawm hws. Qhov kev ua kom loog no yog vim ob qho tib si nruab nrab thiab ntu kev ua haujlwm. Txo cov kev sib sau ua ke, platelet adhesion thiab thrombosis los ntawm inhibiting qhov synthesis ntawm thromboxane A2 hauv platelets.

Hauv cov menyuam mos yug tshiab, salicylates tuaj yeem txav bilirubin los ntawm kev koom nrog albumin thiab pab txhawb kev loj hlob ntawm bilirubin encephalopathy.

Kev nkag mus rau hauv cov kab noj hniav sib koom tes yog nrawm hauv qhov muaj hyperemia thiab edema thiab maj mam nyob rau hauv qhov xwm txheej loj ntawm qhov mob o.

Thaum acidosis tshwm sim, feem ntau ntawm cov salicylate hloov dua siab tshiab rau cov tsis-ionized acid, uas nkag mus rau hauv cov ntaub so ntswg zoo, nrog rau mus rau lub hlwb.

Nws yog tsuas yog tshwj xeeb los ntawm kev ua kom muaj kev zais cia rau hauv cov tubules ntawm ob lub raum tsis hloov (60%) thiab hauv daim ntawv ntawm metabolites. Kev txiav tawm cov salicylate tsis hloov pauv nyob ntawm lub pH ntawm cov zis (nrog rau kev tso zis ntau dhau, ionization ntawm salicylates nce, lawv cov kev ua kom rov muaj mob loj dua, thiab qhov kev nthuav tawm nce ntxiv). T1 / 2 ntawm acetylsalicylic acid yog kwv yees li 15 feeb. T1 / 2 ntawm salicylate thaum noj tsawg kawg yog 2-3 teev, nrog qhov nce ntxiv nws yuav nce ntxiv ntev txog 15-30 teev. Hauv cov menyuam yug tshiab, kev txiav salicylate ntau qeeb dua li cov laus.

Sanovask Siv hauv cev xeeb tub thiab menyuam yaus

Contraindicated nyob rau hauv I thiab III trimesters ntawm cev xeeb tub. Hauv lub sijhawm thib ob ntawm kev xeeb tub, kev nkag mus ib zaug muaj peev xwm ua tau raws li cov cim nruj me ntsis.

Contraindication: menyuam lub hnub nyoog (txog 15 xyoos - qhov pheej hmoo ntawm tus mob Reye syndrome hauv cov menyuam yaus hyperthermia vim yog kis kab mob khaub thuas).

Dosage Sanovask

Ib Leeg. Rau cov neeg laus, ib koob tshuaj nws txawv ntawm 40 mg rau 1 g, ib hnub - los ntawm 150 mg txog 8 g, ntau zaus ntawm kev siv - 2-6 zaug / hnub.

Kev siv cov tshuaj acetylsalicylic acid ua cov tshuaj tiv thaiv kab mob hauv ib koob tshuaj 5-8 g txhua hnub vim muaj ntau qhov tshwm sim ntawm kev phiv los ntawm txoj hnyuv.

Ua ntej kev phais mob, txhawm rau kom los ntshav thaum phais thiab tom qab lub sijhawm txiav, koj yuav tsum tsis txhob noj salicylates li 5-7 hnub.

Thaum lub sij hawm kho ntev, kev kuaj ntshav dav dav thiab fecal occult blood test yuav tsum ua.

Lub sijhawm ntawm kev kho mob (tsis tau sab laj nrog kws kho mob) yuav tsum tsis pub ntau tshaj 7 hnub thaum tshuaj kho mob ua kom loog thiab ntau dua 3 hnub ua ib qho tshuaj tiv thaiv kab mob.

Thaum mus khomob, tus neeg mob yuav tsum yauv tsum tsis haus cawv.

Cev xeeb tub thiab lactation

Cev xeeb tub

Kev siv cov ntsev loj ntawm salicylates hauv thawj 3 lub hlis ntawm cev xeeb tub yog cuam tshuam nrog kev nce ntxiv ntawm cov me nyuam hauv plab tsis zoo (ua rau lub qhov ncauj sab sauv, lub plawv tsis zoo). Kev teem caij ntawm salicylates hauv thawj peb lub hlis ntawm cev xeeb tub yog contraindicated.

Hauv lub hlis thib ob ntawm cev xeeb tub, salicylates tsuas yog yuav tsum tau coj mus rau hauv tus lej ntsuas nruj me ntsis ntawm kev pheej hmoo thiab cov txiaj ntsig rau leej niam thiab tus menyuam hauv plab, zoo dua hauv cov koob tshuaj tsis pub tshaj 150 mg / hnub thiab rau lub sijhawm luv.

Hauv lub sijhawm peb lub hlis dhau los ntawm cev xeeb tub, salicylates hauv kev txhaj tshuaj ntau dua (ntau dua 300 mg / hnub) ua rau inhibition ntawm kev ua haujlwm, ntxov ua haujlwm ntawm cov leeg ntshav ntawm tus menyuam hauv plab, nce ntshav hauv niam thiab tus menyuam, thiab kev tswjfwm tam sim ua ntej yug menyuam tuaj yeem ua rau mob ntshav khov, tshwj xeeb tshaj yog cov menyuam tsis tau yug menyuam ntxov. Kev teem caij ntawm salicylates hauv peb lub hlis kawg ntawm cev xeeb tub yog contraindicated.

Siv thaum lactation

Salicylates thiab lawv cov metabolites hauv cov khoom me me kis mus rau niam mis. Kev noj cov salicylates ntau thaum lub sijhawm lactation tsis yog nrog kev txhim kho cov nyom hauv tus menyuam thiab tsis tas yuav tsum tsis tsum txog kev pub niam mis rau menyuam noj. Txawm li cas los xij, nrog kev siv tshuaj ntev los yog teem caij ntau dua, pub mis rau noj yuav tsum nres tam sim ntawd.