Diphenhydramine - cov lus qhia rau kev siv, tso tawm daim ntawv, cim, tshaj tawm, phiv thiab analogues

Lub ntsiab, tseem ua tshuaj yog DiphenhydramineCov. Lub tshuab kev ua ntawm kev ua raws li kev ua kom tsis txhob muaj kev cuam tshuam ntawm cov tshuaj rau hauv nruab nrab, cholinergic lug, thiab qhov thaiv cov H3-histamine receptors hauv lub hlwb. Diphenhydramine relieves bouts los ntawm khaus, nqaij o, hyperemia, tiv thaiv spasms ntawm cov leeg nqaij mos, muaj cov txiaj ntsig zoo rau capillary permeabilityCov. Kev noj cov lus hauv qhov ncauj ua rau lub siab luv luv ntawm lub loog hauv lub qhov ncauj kab noj hniav. Cov tshuaj muaj antiparkinsonian, hypnotic, sedative, antiemetic cuam tshuam. Vim tias qhov txhaws ntawm cholinergic receptors, lub ganglia txo cov ntshav siab, thiab yuav ua rau muaj ntxiv hypotensionCov. Hauv cov tib neeg muaj mob vwm thiab lub hlwb hauv cheeb tsam puas, txawm tias Diphenhydramine koob tshuaj tsawg kawg tuaj yeem tsim txom qaug dab peg qaug dab peg, thiab ntawm EEG, kev ua kom muaj kev puas ntsoog rov qab los yog pom. Cov tshuaj yog qhov zoo tshaj hauv bronchospasmprovoked los ntawm kev siv histamine liberals (morphine, tubocurarine). Cov tshuaj tsawg kawg yog siv tau rau bronchospasm ntawm kev tsis haum ntawm keeb kwm genesis. Nrog rov qab noj dua, noj tshuaj pab pw tsaug zog thiab cuam tshuam nrog lub suab zoo dua. Cov tshuaj pib ua ib teev tom qab noj, cov nyhuv siv tau ntev txog 12 teev.

Tso tawm daim ntawv thiab muaj pes tsawg leeg

Dosage cov ntaub ntawv ntawm diphenhydramine:

• Cov ntsiav tshuaj: dawb, puag ncig tiaj-cylindrical duab nrog bevel (10 pcs. Hauv cov hlwv ntim cov khoom ntim, hauv daim npav ntawm daim phaib 1, 2, 3 lossis 5 pob, 10 pcs. Hauv ib qho bezeljacheykovy contour ntim, hauv ib lub hnab ntawv 1 ntim lossis hauv ib pob ntawv ntawm pob ntawv 1, 2 lossis 3 pob, 10 pcs. Lossis 20 pcs. Hauv cov thawv iav tsaus, hauv thawv ntawv tuab 1 tuaj yeem),
• Kev daws rau qhov tso ntshav (i / v) thiab tshuaj intramuscular (i / m) kev tswj hwm: tsis muaj xim tsis muaj pob tshab kua hauv ampoules ntawm 1 ml (5 pcs. Hauv cov hlwv pob, hauv thawv ntawv thawv 1 lossis 2 pob, 10 pcs. 10 pcs. Hauv blister sawb ntim, hauv cardboard bundle 2 pob, 10 pcs. Hauv lub tshuab blister, hauv ib daim card qhwv pob 1 pob).

• Ntsiav tshuaj: diphenhydramine hydrochloride, hauv 1 pc. - 50 mg
• Tshuaj: diphenhydramine, hauv 1 ml - 10 mg.

• Ntsiav tshuaj: dej-soluble methyl cellulose - 0.326 mg, lactose monohydrate (mis nyuj qab zib) - 75 mg, colloidal silicon dioxide (aerosil) - 0.76 mg, hmoov txhuv pob kws - 23.154 mg, stearic acid - 0.76 mg,
• Tshuaj: dej rau kev txhaj tshuaj.

Kev ntsuas rau siv

• Kev ua xua, nrog rau ua npaws kub taub hau, urticaria, angioedema,
• Hemorrhagic vasculitis,
• Kev ua xua rau kev ua xua,
• Ntshav dej mob
• Dag
• Vasomotor rhinitis,
• Cov pob khaus khaus
• Kev pw tsaug zog tsis meej, raws li kev kho mob hlwb lossis hauv kev sib xyaw nrog cov tshuaj tsaug zog,
• Ntuav cev xeeb tub
• Huab cua thiab nqhuab,
• Meniere's Syndrome,
• Nyiam Ua Ntej.

Cov Yuav Tsum Tau Ua

• Ua kom mob ncauj plab ntawm lub duodenum thiab / lossis mob plab,
• Bronchial hawb pob,
• Lub ntsej muag kaw lub ntsej muag,
• Qhov ncauj zais zis
• Hypertrophy ntawm lub qog prostate,
• Tshuaj qaug dab peg
• Cov tshuaj tiv thaiv tsis haum rau diphenhydramine.

Nrog kev saib xyuas thiab rau cov cim nruj me ntsis, diphenhydramine tau sau tseg thaum cev xeeb tub thiab thaum pub niam mis, tsuas yog xav tau txiaj ntsig rau leej niam tshaj qhov yuav ua rau muaj kev pheej hmoo rau menyuam lossis menyuam.

Tsuas tshuaj thiab tswj hwm

• Ntsiav tshuaj: noj ntawm ncauj. Kev noj tshuaj rau cov neeg mob laus: raws li cov tshuaj noj pw tsaug zog - 50 mg thaum caij pw, kev kho mob - 30-50 mg 1-3 zaug hauv ib hnub, rau 10-15 hnub. Rau cov menyuam yaus, ib koob tshuaj tsuas yog: txog li 1 xyoos - 2-5 mg, txij li 2 txog 5 xyoos - 5-15 mg, txij li hnub nyoog 6 txog 12 xyoos - 15-30 mg,
• Kev daws rau cov tshuaj ua kom ncaj thiab intramuscular: rau cov neeg mob cov neeg laus, txhaj tshuaj rau hauv lub cev ntawm 50 txog 250 mg, tso dej nrog tshuaj - 20-50 mg. Outwardly pom zoo 1-2 zaug hauv ib hnub.

Sab sij huam

Kev siv cov tshuaj diphenhydramine tuaj yeem ua rau mob tshwm sim:

• Tej zaum: nkees nkees, ua tsis taus pa ntawm lub qhov ncauj mucosa, tsis tshua mloog, dav dav tsis muaj zog, hauv cov menyuam yaus - kev txhim kho paradoxical ntawm insomnia, zoo siab thiab tsis xis nyob,
• Tsis tshua muaj: mob taub hau, kiv taub hau, cuam tshuam ntawm kev ua haujlwm ntawm lub zog, xeev siab, lub qhov ncauj qhuav, kev tawm suab, tshee, paresis ntawm kev pab.

Cov lus qhia tshwj xeeb

Tus neeg mob thaum lub sijhawm siv cov tshuaj pom zoo kom tsis txhob muaj lub hnub ci hluav taws xob, nws yuav tsum tso tseg txoj kev haus cawv.

Thaum cev xeeb tub thiab pub niam mis, cov tshuaj yuav tsum raug siv los ntawm kev saib xyuas mob nkeeg.

Nws yog ntawv ceeb toom nrog ceev faj rau cov neeg mob koom nrog cov kev phom sij ntawm kev ua haujlwm, kev nqis tes ua haujlwm uas yuav tsum muaj kev cuam tshuam psychomotor ceev thiab nce siab.

Yeeb tshuaj sib cuam tshuam

Kev siv cov diphenhydramine nce kev ua haujlwm ntawm cov tshuaj uas thaiv cov hlab ntsha hauv nruab nrab, txhim kho qhov kev txiav txim ntawm ethanol.

Kev sib xyaw nrog monoamine oxidase inhibitors (MAO) nce qhov kev ua haujlwm anticholinergic ntawm cov tshuaj.

Qhov tawm tsam kev xav tshwm sim tawm tsam keeb kwm yav dhau los ntawm kev sib koom ua ke nrog psychostimulants.

Kev siv ib txhij ntawm cov tshuaj txo cov nyhuv emetic ntawm apomorphine hauv kev kho mob ntawm kev lom.

Cov tshuaj tsub ntxiv cov tshuaj anticholinergic zoo ntawm cov tshuaj anticholinergic.

Cov tshuaj tiv thaiv ntawm Diphenhydramine yog: Diphenhydramine-ROS, Diphenhydramine-UBF, Diphenhydramine-UVI, Diphenhydramine-Vial, Diphenhydramine Bufus, Dramina, Kalmaben.

Diphenhydramine: cov nqi hauv cov khw muag tshuaj online

DIMEDROL 50mg 10 pcs. ntsiav tshuaj

Diphenhydramine 50 mg ntsiav tshuaj 10 pcs.

DIMEDROL 50mg 10 pcs. ntsiav tshuaj

DIMEDROL 50mg 20 pcs. ntsiav tshuaj

Diphenhydramine 50 mg ntsiav tshuaj 20 pcs.

Diphenhydramine Ntsiav Tshuaj 50mg No. 20

Diphenhydramine (rau kev txhaj tshuaj) 10 mg / ml tov rau tshuaj thiab tso tshuaj thawj zaug 1 ml 10 pcs.

DIMEDROL 10mg / ml 1ml 10 pcs. txhaj tshuaj intramuscular

Diphenhydramine (rau kev txhaj tshuaj) 10 mg / ml tov rau tshuaj thiab tso tshuaj thawj zaug 1 ml 10 pcs.

Diphenhydramine (rau kev txhaj tshuaj) 10 mg / ml tov rau tshuaj thiab tso tshuaj thawj zaug 1 ml 10 pcs.

DIMEDROL 10mg / ml 1ml 10 pcs. kev daws rau kev tso ntshav thiab intramuscular

DIMEDROL 10mg / ml 1ml 10 pcs. kev daws rau kev tso ntshav thiab intramuscular

Cov ntaub ntawv hais txog cov tshuaj raug muab dav dav, muab rau kev qhia tawm thiab tsis hloov chaw cov lus qhia. Kev siv tshuaj rau tus kheej yog qhov txaus ntshai rau kev noj qab haus huv!

Tus mob uas tsis tshua muaj mob yog Kuru's kab mob. Tsuas yog cov neeg sawv cev ntawm pawg neeg Fore hauv New Guinea mob nrog nws. Tus neeg mob tuag ntawm kev luag. Nws ntseeg tau tias qhov ua rau tus mob yog noj tib neeg lub hlwb.

Raws li ntau tus kws tshawb fawb, cov vitamins complex yog qhov tsis muaj txiaj ntsig rau tib neeg.

Muaj 74 xyoo nyob hauv tebchaws Australian yawg James Harrison tau los ua neeg muab ntshav li 1,000 zaus. Nws muaj ib hom ntshav uas tsis tshua muaj, cov tshuaj tiv thaiv uas pab cov menyuam mos liab uas muaj ntshav tsawg txaus kom ciaj sia taus. Yog li, Australian thiaj cawm tau ntau txog ob lab tus menyuam.

Txhua tus neeg muaj tsis tsuas yog nyias tus ntiv tes, tab sis kuj hais lus.

Thaum lub neej, tus neeg nruab nrab tsim tawm tsis tsawg tshaj li ob lub pas dej loj uas muaj qaub ncaug.

Plaub qho ntawm chocolate tsaus muaj txog ob puas calories. Yog li yog tias koj tsis xav tau zoo dua, nws zoo dua tsis txhob noj ntau tshaj li ob lobules ib hnub.

Tib neeg cov ntshav "khiav" los ntawm cov hlab ntsha hauv qab qhov siab, thiab yog tias nws txoj kev ncaj ncees tau ua txhaum, nws tuaj yeem tua txog 10 meters.

Cov tib neeg uas tau noj tshais ua ntu zus feem ntau yog cov muaj rog.

Tus neeg noj tshuaj tiv thaiv kab mob feem ntau yuav rov qab muaj kev nyuaj siab. Yog tias ib tug neeg mob nrog kev nyuaj siab ntawm nws tus kheej, nws muaj txhua lub sijhawm tsis nco qab txog lub xeev no tas mus li.

Raws li kev tshawb fawb, cov poj niam uas haus ob peb khob npias lossis cawv txiv hmab ib lim tiam muaj feem ntau yuav muaj mob khees xaws mis.

Ntxiv rau tib neeg, tsuas yog ib tus tsiaj muaj sia nyob ntawm ntiaj chaw ntiaj teb - dev, raug kev txom nyem los ntawm prostatitis. Cov no yog peb cov phooj ywg ncaj ncees tshaj plaws.

Qhov kub siab tshaj plaws ntawm lub cev tau sau cia ntawm Willie Jones (USA), uas tau nkag rau hauv tsev kho mob nrog qhov kub txog 46,5 ° C.

Thaum txham, peb lub cev ua haujlwm tsis tiav. Txawm lub plawv nres.

Kev ua haujlwm uas ib tus neeg tsis nyiam yuav muaj kev phom sij rau nws lub siab ntau dua li qhov uas tsis muaj haujlwm hlo li.

Yog tias koj luag nyav tsuas yog ob zaug ib hnub, koj tuaj yeem txo cov ntshav siab thiab txo qhov kev pheej hmoo ntawm lub plawv thiab mob nkees.

Ib nrab ntawm cov hniav tsis txaus los yog ua tiav adentia tuaj yeem yog qhov tshwm sim ntawm kev raug mob, caries lossis kab mob pos hniav. Txawm li cas los xij, hniav ploj tuaj yeem hloov nrog cov hniav cuav.

Dab tsi yog diphenhydramine

Raws li kev lees paub kev kho mob tau txais kev faib tawm, Diphenhydramine belongs rau histamine receptor blockers thiab tshuaj antiallergic. Cov tshuaj nquag ntawm cov muaj pes tsawg leeg yog diphenhydramine hydrochloride, uas ua haujlwm ntawm lub hauv nruab nrab cov hlab hlwb, inhibiting histamine thiab cholinergic cov qauv nrog lub hlwb txais. Vim tias cov txiaj ntsig zoo li no, spasm ntawm cov leeg du tau tshem tawm, muaj kev pab cuam ntawm tus neeg mob nrog kev ua xua.

Kev Sib Sau thiab daim ntawv ntawm tso tawm

Cov foos ntawm kev tso tawm tshuaj yog txhaj tshuaj thiab ntsiav tshuaj. Thawj zaug tuaj yeem tau noj ntawm qhov ncauj lossis hauv kev rau hauv qhov muag. Tsis tas li ntawd, cov khoom siv rau lub plab qhov quav yog tsim raws cov khoom siv nquag. Qhov muaj pes tsawg leeg thiab kev piav qhia ntawm cov kev npaj tau qhia hauv lub rooj:

Dawb tiaj tus cylindrical nrog lub ntsej muag thiab kev pheej hmoo

Qhov kev cia siab ntawm diphenhydramine, mg

30, 50 lossis 100 rau 1 pc. / 20 rau cov menyuam yaus

Lim dej rau kev txhaj tshuaj

Stearic acid, qos hmoov txhuv nplej siab, colloidal silicon dioxide, lactose

Ampoules ntawm 1 ml, 10 pcs. hauv ib pob nrog cov lus qhia rau kev siv

Cov blisters lossis ib daim hlab ntawm 6 lossis 10 pcs., Pob ntawm ib qho blister txhua

Cov yam ntxwv ntawm lub cev-physic-diphenhydramine

Cov tshuaj cuam tshuam rau blockers ntawm histamine receptors hauv lub hlwb. Vim tias qhov no, diphenhydramine relieves spasm ntawm cov leeg du, txo capillary permeability, tsis muaj zog lub zog ntawm kev tsis haum. Nquag cov khoom ua haujlwm ntawm cov tshuaj loog hauv zos muaj cov haujlwm antiemetic, cov nyhuv sedative, cov nyhuv hypnotic.

Cov tshuaj ua rau cov tshuaj loog hauv zos, uas ua tau nws tus kheej hauv qhov txiav txim siab luv luv ntawm lub qhov ncauj ntawm qhov ncauj ntawm qhov ncauj, muaj cov nyhuv antispasmodic. Diphenhydramine muaj txiaj ntsig zoo dua yog tias kev txha tshuaj tiv thaiv kab mob bronchospasm tshwm sim los ntawm histamine liberalizers (morphine), tsawg dua - thaum muaj kev tsis haum tshuaj. Cov tshuaj tsis ua hauj lwm zoo tiv thaiv kev mob ntsws asthma, tuaj yeem ua ke nrog bronchodilators (Theophylline, Ephedrine).

Diphenhydramine antagonizes nrog cov nyhuv ntawm histamine, nce ntshav siab. Hauv cov neeg mob uas muaj ntshav ntau lub cev tsis txaus, kev tswj hwm kev noj qab haus huv ntawm diphenhydramine tuaj yeem ua rau txo qis hauv lub siab thiab nce hypotension vim muaj cov nyhuv ganglion thaiv kev. Nrog rau cov kev puas tsuaj hauv ib cheeb tsam ntawm lub hlwb thiab epilepsy, cov tshuaj muaj peev xwm ua kom qaug dab peg thiab ua rau mob rov tuaj cev.

Cov tshuaj pib ua nyob rau hauv ob peb feeb, nws cov nyhuv kav txog 12 teev. Diphenhydramine khi rau cov ntshav plasma ntau npaum li 98%, yog cov tshuaj tiv thaiv kab mob hauv lub siab, lub ntsws thiab lub raum, tso tawm los ntawm lub raum, nrog rau cov kua mis hauv daim ntawv ntawm conjugate metabolites nrog glucuronic acid. Cov khoom ua kom nquag plias ntawm muaj pes tsawg leeg nkag mus rau hauv cov ntshav-hlwb teeb meem, ib qhov keeb kwm muaj nyob hauv niam cov kua mis.

Pab pawg kws tshuaj:

ATX Cov Cai R06AA02

Pharmacological kev txiav txim
Blocker ntawm H1-histamine receptors ntawm thawj tiam. Blocks H1-histamine receptors thiab tshem tawm cov kev cuam tshuam ntawm histamine sib kho los ntawm hom receptor. Kev ua ntawm lub hauv nruab nrab lub paj hlwb vim thaiv ntawm N₃- histamine receptors ntawm lub paj hlwb thiab inhibition ntawm central cholinergic lug. Nws tau tshaj tawm cov kev tawm tsam antihistamine, txo qis lossis tiv thaiv histamine du pob txha caj qaum, nce capillary permeability, cov ntaub so ntswg o, khaus thiab hyperemia. Nws ua rau cov tshuaj loog hauv zos (thaum noj ntawm qhov ncauj, luv luv ntawm lub cev ntawm lub qhov ncauj ntawm qhov ncauj tshwm sim), thaiv cov kab mob ganglia cholinergic receptors (txo qis ntshav siab) thiab lub hauv nruab nrab lub paj hlwb, thiab muaj sedative, hypnotic, antiparkinsonian thiab antiemetic effect. Antagonism nrog cov tshuaj histamine tshwm rau ntau dua nrog rau kev cuam tshuam rau hauv lub zos cov vascular qhov kev hloov pauv thiab kev ua xua dua li cov kab mob rau ib puag ncig, i.e. txos cov ntshav siab. Hauv cov neeg muaj lub hlwb puas hauv zej zog thiab mob vwm, nws ua kom mob (txawm tias yog tshuaj tsawg) cov kev tso tawm los ntawm EEG thiab tuaj yeem ua rau qaug dab peg. Sedative thiab hypnotic cov teebmeem ntau dua nrog hais dua.
Qhov pib ntawm kev ua tau sau tseg 15-60 feeb tom qab kev haus, lub sijhawm ntawm -12 teev

Cov Tshuaj Pharmacokinetics
Sai sai nqus nyob rau hauv lub gastrointestinal ib ntsuj av. Bioavailability yog 50%. TCmax - 2040 min (qhov siab tshaj plaws yog txiav txim siab hauv lub ntsws, hnoos qeev, raum, siab, lub hlwb thiab cov leeg). Kev sib txuas lus nrog cov ntshav plasma protein - 98-99%. Nkag tau los ntawm cov ntshav-hlwb teeb meem. Nws yog metabolized feem ntau hauv daim siab, qee feem hauv lub ntsws thiab lub raum. Nws yog tawm los ntawm cov ntaub so ntswg tom qab 6 teev. Lub sijhawm ib nrab yog 4-10 teev. Thaum nruab hnub, nws tau tawm los tag nrho los ntawm lub raum hauv daim ntawv ntawm metabolites conjugated rau glucuronic acid. Tus nqi tseem ceeb yog ua rau hauv cov mis thiab yuav ua rau muaj kev cuam tshuam sedative hauv cov menyuam mos (qhov teeb meem paradoxical muaj los ntawm kev zam ntau dhau los yuav pom).

Kev ntsuas rau siv
Kev ua xua rau kev tiv thaiv kev ua xua, ua xua rhinitis, mob ntev urticaria, pruritic dermatoses, dermatographism, mob taub hau, hauv kev kho mob ntawm anaphylactic, Quincke edema thiab lwm yam kev ua xua.
Insomnia, chorea, Meniere's syndrome, mob hiav txwv thiab huab cua, ua mob los tiv thaiv kev mob hlwb.

Cov Yuav Tsum Tau Ua
Cov tshuaj tiv thaiv lub cev tsis haum, lub qhov muag kaw lub ntsej muag, lub qhov txhab mob prostatic hyperplasia, mob stenosing peptic ua rau lub plab thiab duodenum, stenosis ntawm lub zais caj dab, ntsws ntsws, mob vwm.
Cov menyuam yaus hnub nyoog txog 7 xyoo (rau daim ntawv no ntau npaum).

Nrog saib xyuas - cev xeeb tub, lactation.

Tsuas tshuaj thiab tswj hwm
Sab hauv. Cov neeg laus thiab cov menyuam hnub nyoog 14 xyoos, 25-50 mg (1 / 2-1 ntsiav tshuaj) 1-3 zaug hauv ib hnub. Qhov siab tshaj plaws koob tshuaj yog 100 mg, ib hnub - 250 mg. Nrog insomnia - 50 mg 20-30 feeb ua ntej yuav mus pw. Nrog rau cov kev mob tshwm sim - 25-50 mg txhua txhua 4-6 teev yog tsim nyog.
Cov menyuam yaus hnub nyoog 7 txog 14 xyoos 12,5 - 25 mg (1 / 4-1 / 2 ntsiav tshuaj) 1-3 zaug hauv ib hnub.

Sab sij huam
Kev nkees nkees, lub qhov ncauj qhuav, loog ntawm lub qhov ncauj mucosa, kiv taub hau, tshee tshee, xeev siab, mob taub hau, feem ntau qaug zog, poob qis ntawm cov tshuaj tiv thaiv psychomotor, ua kom lub ntsej muag zoo nkauj, paresis ntawm kev pab, kev ua tsis tau zoo ntawm kev txav. Hauv cov menyuam yaus, txoj kev txhim kho paradoxical ntawm insomnia, txob taus thiab zoo siab yog ua tau.

Noj ntau dhau
Cov tsos mob kev nyuaj siab ntawm lub hauv nruab nrab lub paj hlwb, txoj kev loj hlob ntawm kev zoo siab (tshwj xeeb tshaj yog nyob rau hauv cov menyuam yaus) lossis kev nyuaj siab, lub qog ua kua, lub qhov ncauj qhuav, paresis ntawm cov kabmob ntawm cov hnyuv, thiab lwm yam.
Kev Kho Mob: tsis muaj ib qho tshuaj tshwj xeeb. Lub plab zom mov. Yog tias tsim nyog, cov kev kho mob tshwm sim: tshuaj uas ua rau muaj ntshav siab ntxiv, oxygen, tswj xyuas ntshav ntshav-hloov dej ntawm lub cev.
Tsis txhob siv epinephrine thiab analeptics.

Kev cuam tshuam nrog lwm yam tshuaj
Txhim kho qhov kev txiav txim ntawm ethanol thiab tshuaj uas inhibit lub hauv paus ntawm lub paj hlwb.
Monoamine oxidase inhibitors txhim kho anticholinergic kev ua si ntawm diphenhydramine.
Antagonistic sib cuam tshuam tau sau tseg nrog kev sib koom ua ke nrog psychostimulants.
Txo cov txiaj ntsig ntawm apomorphine ua qhov emetic hauv kev kho mob ntawm lom.
Txhim kho cov tshuaj anticholinergic zoo uas cuam tshuam nrog cov tshuaj tiv thaiv anticholinergic.

Cov lus qhia tshwj xeeb
Xyuam xim rau cov neeg mob uas koom nrog cov kev phom sij uas yuav tsum muaj kev saib xyuas ntau dua thiab cov kev puas hlwb ceev. Thaum lub sijhawm kho nrog diphenhydramine, tiv thaiv tshav ntuj thiab ethanol yuav tsum zam.
Nws yog ib qho tsim nyog yuav tsum tau qhia rau tus kws kho mob txog kev siv cov tshuaj no: cov nyhuv antiemetic tuaj yeem ua kom yooj yim rau kev kuaj mob ntawm cov pob txha caj qaum thiab kev paub txog cov tsos mob ntawm kev siv ntau tshaj ntawm lwm cov tshuaj.
Hauv cov menyuam yaus ntawm 1 xyoo txog 7 xyoo, nws raug nquahu kom siv cov ntsiav tshuaj 30 mg (los ntawm 1 xyoo txog 3 xyoo, koob tshuaj txhua hnub ntawm 10-30 mg, muab faib ua 2-3 koob, txij li 4 rau 6 xyoo, ib koob tshuaj txhua hnub ntawm 20 - 45 mg, muab faib ua 2 koob -3 nkag mus).
Hauv cov menyuam yaus txij li 7 hli txog 12 hlis, cov tshuaj yuav siv tau rau hauv cov hmoov uas tau npaj tseg hauv cov chaw ua tshuaj thiab cov chaw tsim tshuaj ntawm cov khw muag tshuaj 3-5 mg 2-3 zaug ib hnub.

Daim ntawv tso tawm
50 mg ntsiav tshuaj
Ntawm 10 lub ntsiav tshuaj hauv lub hlwv qhwv cov hlua-pub dawb los yog hauv lub hlwv nrog lub hlwv ntim. Ntawm 2, 3 lossis 5 blister strip packagings ua ke nrog kev qhia daim ntawv thov raug muab tso rau hauv pob los ntawm daim duab los qhia.

Hnub tas sij hawm
5 xyoos Tsis txhob siv cov tshuaj tom qab hnub tas sij hawm.

Cia rau cov neeg mob
Sau npe B. Hauv qhov chaw qhuav thiab tsaus thiab tsis ncav cuag cov menyuam.

Cov Hnub So Haujlwm
Los ntawm tshuaj.

Thov chaw tsim tshuaj paus / koom haum:
OJSC "Dalhifarm"
680001, Khabarovsk, st. Tashkent, 22.

Pharmacological kev txiav txim

Nws muaj cov tshuaj antihistamine, antiallergic, antiemetic, hypnotic, cov tshuaj loog hauv zos. Cov tshuaj histamine H₁ - receptors thiab tshem tawm qhov cuam tshuam ntawm histamine kev sib kho los ntawm hom receptor. Txo lossis tiv thaiv histamine-vim cov nqaij mos ua rau lub cev txhawm rau txhawm rau nce ntxiv, nce siab capillary permeability, nqaij voos, mob caj dab, thiab hyperemia. Antagonism nrog cov tshuaj histamine tshwm rau ntau dua nrog kev saib xyuas cov vascular qhov chaw nyob rau hauv kev txiav txim siab ntawm mob thiab ua xua piv rau cov kab mob hauv lub cev, i.e. txos cov ntshav siab. Nws ua rau cov tshuaj loog hauv zos (thaum noj ntawm qhov ncauj, muaj lub sijhawm luv luv ua rau tsis hnov ​​tsw ntawm lub qhov ncauj ntawm qhov ncauj), muaj cov nyhuv antispasmodic, thiab thaiv cov cholinergic receptors ntawm autonomic ganglia (txo cov ntshav siab). Thaiv N₃ - histamine txais ntawm lub hlwb thiab inhibits central cholinergic lug. Nws muaj ib qho ua kom loog, hypnotic thiab antiemetic effect. Nws ua hauj lwm zoo dua rau bronchospasm tshwm sim los ntawm histamine liberals (tubocurarine, morphine, sombrevin), rau qhov tsawg dua rau kev siv tshuaj tiv thaiv bronchospasm. Nrog rau mob ntsws asthma, nws tsis ua haujlwm thiab siv ua ke nrog theophylline, ephedrine thiab lwm yam tshuaj kho mob ntsws.

Cov Tshuaj Pharmacokinetics

Thaum noj ntawm qhov ncauj, nws yog sai thiab zoo nqus. Nws khi rau cov protein ntau los ntawm 98-99%. Kev siab tshaj plaws (C_tah) hauv ntshav yog tiav li 1-4 teev tom qab kev noj mov. Feem ntau ntawm kev noj tshuaj diphenhydramine yog metabolized hauv lub siab. Ib nrab-lub neej (T_1/2) yog 1-4 teev .Nws tau dav faib rau hauv lub cev, kis los ntawm cov ntshav-tiv thaiv lub hlwb thiab cov placenta. Muaj nyob rau hauv cov mis thiab yuav ua rau muaj mob hauv cov menyuam mos. Thaum nruab hnub, nws tau tawm los ntawm lub cev feem ntau hauv daim ntawv ntawm benzhydrol conjugated nrog glucuronic acid, thiab tsuas yog nyob rau hauv ib qho me me - tsis hloov pauv. Qhov siab tshaj plaws tau tsim kho 1 teev tom qab noj, lub sijhawm ua haujlwm yog ntawm 4 txog 6 teev.

Sab sij huam

Los ntawm cov leeg hlwb thiab cov haujlwm hauv lub cev: qhov tsis muaj zog, nkees, ua rau lub zog tsis txaus, txo qis, kiv taub hau, tsaug zog, mob taub hau, ua kom tsis muaj kev sib koom tes ntawm kev txav, ntxhov siab, nce siab (tshwj xeeb tshaj yog nyob hauv menyuam yaus), txob taus, poob siab, insomnia, zoo siab, tsis meej pem , tshee tshee, mob neuritis, mob nriaj, mob pob txha caj qaum, pom qhov muag tsis zoo, daim ntawv pov thawj tsis muaj qhov muag, mob loog mob, mob ntsws. Hauv cov neeg mob uas muaj mob puas hlwb lossis puas hlwb, nws ua kom mob (txawm hais tias siv tshuaj tsawg) cov mob cais tawm ntawm EEG thiab tuaj yeem ua rau qaug dab peg.

Los ntawm cov hlab plawv system thiab ntshav: hypotension, palpitations, tachycardia, extrasystole, agranulocytosis, thrombocytopenia, hemolytic anemia.

Los ntawm cov khoom noj hauv lub cev: lub qhov ncauj qhuav, ua pa luv luv ntawm lub qhov ncauj ntawm qhov ncauj, tsis nco qab, ntuav, mob epigastric, ntuav, raws plab, cem quav.

Los ntawm cov kab mob genitourinary: nquag tso zis thiab / los yog tso zis nyuaj, tso zis cia, ua poj niam coj khaub ncaws thaum ntxov.

Ntawm ib feem ntawm cov txheej txheem ua pa: lub qhov ntswg qhuav thiab caj pas, txhaws ntswg, ua pa ntawm lub ntsej muag txhaws, nruj ntawm lub hauv siab thiab ua tsis taus pa.

Kev ua xua rau: xoo pob, urticaria, anaphylactic shock.

Lwm yam: tawm hws, ntawj txias, tawm qhov muag.

Noj ntau dhau

Cov tsos mob: qhov ncauj qhuav, ua pa nyuaj, muaj mydriasis tsis tu ncua, ntsej muag ntsej muag, kev nyuaj siab lossis ntxhov siab (ntau zaus hauv cov menyuam yaus) ntawm lub hauv nruab nrab cov hlab ntsha, tsis meej pem, hauv menyuam yaus - kev txhim kho ntawm qaug dab peg thiab kev tuag.

Kev Kho Mob: induction ntuav, pais plab lav, tswj kev siv hluav ncaig hluav taws xob, ua pa thiab pab txhawb nrog saib xyuas ua pa thiab ntshav siab.

Hauv tshuaj ntsiav

Rau cov laus, Cov ntsiav tshuaj Diphenhydramine raug noj nyob rau hauv ib qho li 30-50 mg 1-3 zaug / hnub hauv ib hnub ntawm 10-15 hnub. Koob tshuaj ib zaug rau cov menyuam hnub nyoog qis dua 2-5 mg, tus menyuam hnub nyoog 2-5 xyoos yuav tsum tau txais 5-15 mg, 6-12 xyoo - 15-30 mg. Diphenhydramine yog siv los ua cov ntsiav tshuaj tsaug zog 50 mg thaum caij pw. Nws tsis tuaj yeem ua dhau qhov ntau npaum li cas los ntawm tus kws kho mob vim qhov nce ntau ntawm kev pheej hmoo ntawm kev tsis zoo. Cov ntsiav tshuaj tau ntxuav nrog dej, coj los tsis hais tus noj mov.

Raws li lub npe "Diphenhydramine" cov tshuaj tiv thaiv tsis muaj, tab sis muaj cov suppositories rau kev siv lub qhov quav uas muaj analgin thiab diphenhydramine, piv txwv li, Analdim. Lawv raug siv los ua tshuaj loog tom qab kev ntxuav kev tawm huv, txhaj rau hauv lub qhov quav ob zaug / hnub. Cov menyuam hnub nyoog 1-4 xyoos tau raug samfwm kom noj ib lub sijhawm, ib tus neeg laus - 1-3 suppositories. Tus yau dua tus menyuam lub hnub nyoog, qhov qis ntawm kev siv cov tshuaj yuav tsum tau siv. Lub chav kawm ntawm kev kho mob kav 1-4 hnub.

Rau siv rau hauv ophthalmology lossis allergology, diphenhydramine tee yog tshuaj. Rau qhov no, 0.2-0.5% hauv kev daws 2% ntawm boric acid yog instilled 1-2 dauv 3-5 zaug / hnub mus rau hauv hnab looj tes sib txuas ua ke kom daws qhov tsis haum. Kev daws tuaj yeem siv tshuaj intranasally, kom tshem tawm cov tsos mob ntawm kev tsis haum rhinitis thiab sinusitis - 0.05 ml ntawm cov tshuaj hauv txhua qhov ntswg ob peb zaug / hnub. Lub chav kawm ntawm kev kho mob yog txiav txim los ntawm tus kws kho mob uas tuaj koom, nws kuj sau cov tshuaj ntau npaum li cas ntawm cov tshuaj.

Diphenhydramine thaum cev xeeb tub

Cov kws kho mob tau sau ntawv rau cov tshuaj kom ceev faj thaum cev xeeb tub thiab lactation, vim diphenhydramine tuaj yeem ua rau muaj kev tsis zoo rau kev loj hlob ntawm tus menyuam. Ua ntej noj kws kho mob yuav tsum ntsuas qhov txiaj ntsig rau leej niam dhau qhov kev pheej hmoo rau tus me nyuam hauv plab, thiab yog tias nws siab dua, sau ntawv noj tshuaj. Nrog rau kev pub niam mis, diphenhydramine dhau mus rau hauv niam cov kua mis, yuav ua rau muaj kev cuam tshuam sedative hauv cov menyuam yug tshiab lossis nce siab tsis txaus. Nrog rau lactation, tshuaj yog contraindicated.

Diphenhydramine rau cov menyuam yaus

Koj tsis tuaj yeem siv Diphenhydramine rau cov menyuam yaus yog tsis muaj kws kho mob cov lus qhia thiab txiav txim siab rau txhua kis ntawm tus kheej, txiav txim siab qhov mob hnyav thiab cov cim qhia rau kev siv. Kev siv cov tshuaj rau kev tswj hwm niam txiv thiab cov tshuaj txhaj yog contraindicated thaum muaj hnub nyoog txog li xya lub hlis, ntsiav tshuaj rau kev tswj hwm qhov ncauj - txog rau xyoo. Soj ntsuam cov tshuaj rau tus me nyuam kom zoo zoo kom tsis txhob muaj kev phom sij ntawm kev phiv tshuaj thiab mob arousal ntau dhau.

Cawv tau zoo

Raws li kev tshawb fawb, cov tshuaj kho kom zoo dua cov nyhuv inhibitory ntawm ethanol nyob rau hauv nruab nrab lub paj hlwb, yog li txhua txoj kev kho cawv thiab haus cawv muaj cawv lossis tshuaj yuav tsum muab pov tseg txhua lub sijhawm thaum kho tshuaj. Kev sib xyaw ntawm cov tshuaj nrog cawv tsis cuam tshuam rau daim siab, ua rau muaj kev pheej hmoo ntawm kev noj tshuaj ntau dhau thiab ua rau qaug cawv los ntawm cov tshuaj cawv.

Cov nqe lus ntawm kev muag khoom thiab kev cia khoom

Cov tshuaj yog xa tawm nrog cov tshuaj noj, khaws cia kom deb ntawm cov menyuam yaus hauv qhov chaw tsaus thaum kub tsis tshaj 30 degrees rau tsib xyoos.

Muaj ntau ntau yam ntawm cov yeeb yaj kiab ntawm cov yeeb tshuaj nrog cov tshuaj qub. Kuj rau ntawm kev muag khoom yog hloov cov tshuaj nrog lwm cov khoom siv, tab sis muaj tib lub txiaj ntsig ntawm lub cev. Cov tshuaj muaj npe:

• Diphenhydramine chloride,
• Diphenhydramine,
• Allergan,
• Diphenyl
• Txhaws ntshav
• Alledril
• Diabenil

Koj tuaj yeem yuav daim ntawv yuav tshuaj hauv khw muag tshuaj lossis hauv khw muag khoom online. Tus nqi ntawm cov tshuaj yog nyob ntawm seb hom (ntsiav tshuaj / daws), kev lag luam npoo thiab qhov tob ntawm cov tshuaj nquag. Tus nqi rau cov tshuaj hauv Moscow cov khw muaj npe hauv lub rooj:

Ampoules 1 ml 10 pcs.

Ntsiav tshuaj 50 mg 10 pcs.

Veronika, hnub nyoog 28 xyoo. Kuv raug kev txom nyem los ntawm insomnia, Kuv tsis tuaj yeem tsaug zog, pov thiab ntev mus, thaum sawv ntxov tom qab kuv sawv. Qhov no tsis zoo cuam tshuam lub peev xwm rau kev ua haujlwm. Ib tug phooj ywg qhia kuv kom noj Diphenhydramine Tablet thaum tsaus ntuj ob zaug ntawm ib lub lim tiam. Kuv tau mloog, thiab muaj kev txaus siab. Cov tshuaj maj mam so, nws tsis ua rau xeev siab thiab ntse "ua tsis tau" hauv ib lub xeev pw.

Leonid, hnub nyoog 38 xyoo. Txhua lub caij nplooj ntoo hlav Kuv pib txham thiab hnoos, vim yog lub paj tawg, cov ntoo tawg. Kuv muaj kev fab tshuaj, tsuas yog Diphenhydramine Ncos tuaj yeem tiv taus nws. Kuv faus lawv rau hauv kuv lub qhov muag kom daws qhov o thiab kua muag, qee zaum kuv tuaj yeem nqus mus rau hauv kuv lub qhov ntswg kom tshem tawm qhov ntswg dej. Cov tshuaj yog qhov zoo, thiab nws pheej yig, tsis zoo li cov txhais tau tias niaj hnub.

Elizabeth, 32 xyoo. Lub hlis tas los kuv tau ntsib kev khaus khaus. Kev ua haujlwm yog cuam tshuam nrog kev siv tshuaj hauv tsev, thiab lub cev tau ua haujlwm. Tau ntev kuv tau nrhiav kev kho qhov teeb meem uas tuaj yeem pab tau, thaum kawg kuv tau tsawm ntawm Diphenhydramine ntsiav tshuaj. Kuv haus lawv thaum hmo ntuj, vim hais tias cov tshuaj ua rau tsaug zog thaum nruab hnub, thiab kuv tseem pleev cov pob nrog qab zib. Muaj kev vam meej, tab sis tsis nrawm li qhov kuv xav tau.

Vitaliy, 41 xyoo. Thawj thawj lub hlis thiab ib nrab dhau los, Kuv tau ntsib kev kub ntxhov, kuv tau pib mob hauv lub tsheb. Kuv hnov ​​tias Diphenhydramine kov tau zoo nrog cov cim qhia ntawm kev muaj mob, Kuv txiav txim siab mus kawm hauv chav kawm. Cov tshuaj twb dhau los - nws ua rau koj tsaug tsaug zog, thiab yog li ntawd peb tsis tham txog kev tsav tsheb. Kuv yuav nrhiav qhov tshiab tam sim no ntawm Diphenhydramine tsav tsheb kuv tus kheej.

Diphenhydramine ntsiav tshuaj, cov lus qhia rau kev siv

30-50 mg ib zaug txog peb zaug hauv ib hnub, lub sijhawm kho yog 10-15 hnub.

Nrog insomnia 50 mg yog tau sau tseg ib nrab ib teev ua ntej yuav mus pw.

Ntawm postencephalic, idiopathic parkinsonism thaum pib kho 25 mg peb zaug ib hnub, hauv kev siv tshuaj ntxiv rau maj mam nce mus rau 50 mg 4 zaug hauv ib hnub.

Nrog kev mob taub hau txhua txhua 6 teev koj yuav tsum noj 25-50 mg ntawm ntsiav tshuaj.

Kev sib txuam

Diphenhydramine txhim kho kev txiav txim siab ntawm cov tshuaj uas tiv thaiv kev puas siab puas ntsws. Thaum muab sib xyaw nrog hlwb hlwb cov kev thaiv kev tsis zoo raug kaw tseg. MAO inhibitors nce lub anticholinergic kev ua si ntawm cov tshuaj. Hauv kev kho mob ntawm kev lom, intoxication, cov tshuaj txo cov nyhuv apomorphine.

Diphenhydramine thiab haus dej cawv

Nws yog contraindicated yuav siv cov tshuaj nrog cawv. Cov cawv ntawm cov cawv yog qhov ua kom zoo, muaj cov nyhuv hypnotic ntau zog, muaj kev puas tsuaj rau lub cev hnyav. Qhov txiaj ntsig tsis tuaj yeem kwv yees tau, tshwj xeeb tshaj yog thaum siv cov koob tshuaj loj. Vodka nrog diphenhydramine yuav yog cov dej haus kawg hauv lub neej ntawm ib tus neeg uas tau haus cov dej sib xyaw no, cov koob tshuaj tsis haum tuaj yeem yog tsawg heev thaum ua ke nrog haus cawv.