Gliclazide Canon: cov lus qhia rau kev siv ntsiav tshuaj
Gliclazide Canon: cov lus qhia rau kev siv thiab tshuaj xyuas
Lub npe Latin: Gliclazide Canon
ATX Code: A10BB09
Tus nquag ua hauj lwm: Gliclazide (Gliclazide)
Chaw tsim tshuaj paus: Kanonfarma ntau lawm, CJSC (Russia)
Hloov kho cov lus piav qhia thiab yees duab: 07/05/2019
Cov nqi hauv khw muag tshuaj: los ntawm 105 rubles.
Glyclazide Canon yog tshuaj qhov ncauj hypoglycemic ntawm sulfonylurea pawg ntawm tiam thib ob.
Tso tawm daim ntawv thiab muaj pes tsawg leeg
Daim ntawv tso tshuaj - siv cov tshuaj tawm mus ntev: yuav luag dawb lossis dawb, me ntsis marbling ntawm qhov chaw, puag ncig biconvex, 60 mg txhua tus nrog rau cov kab sib faib (Gliclazide Canon 30 mg: 10 pcs. Hauv pob blister, hauv 3 lossis 6 pob ntawm thawv) , 30 pcs. Hauv cov hlwv pob, hauv ib pob ntawv los ntawm 1 lossis 2 pob, Canon Glyclazide 60 mg: 10 pcs. Hauv cov hlwv ntim, hauv ib pob ntawv los ntawm 3 lossis 6 pob, 15 pcs. cardboard pob 2 lossis 4 pob khoom, hauv Txhua pob ntawv kuj muaj cov lus qhia rau kev siv Glyclazide Canon).
Composition 1 ntsiav tshuaj:
- cov tshuaj nquag: gliclazide - 30 lossis 60 mg,
- Cov khoom siv pabcuam (30/60 mg): magnesium stearate - 1.8 / 3.6 mg, microcrystalline cellulose - 81.1 / 102.2 mg, hydrogenated zaub roj - 3.6 / 7.2 mg, hypromellose - 50 / 100 mg, colloidal silicon dioxide - 3.5 / 7 mg, mannitol - 10/80 mg.
Cov Tshuaj Hauv Tshuaj
Glyclazide - lub tshuaj nquag ntawm Glyclazide Canon, yog ib ntawm sulfonylurea derivatives thiab yog tus sawv cev hypoglycemic rau kev tswj hwm qhov ncauj. Nws txawv ntawm cov tshuaj zoo sib xws nyob ib puag ncig ntawm N-muaj heterocyclic nplhaib nrog kev ua kom cov kabmob endocyclic.
Gliclazide pab txo cov ntshav qabzib hauv siab, uas yog muab los ntawm kev ua kom muaj zog ntawm cov tshuaj insulin los ntawm beta hlwb ntawm islets ntawm Langerhans. Lub sijhawm ntawm cov nyhuv ntawm nce cov ntsiab lus ntawm cov kua dej postprandial thiab C-peptide txuas ntxiv tom qab 2 xyoo ntawm kev kho. Qhov khoom ntawd, ntxiv rau cuam tshuam rau cov metabolism hauv carbohydrate, muaj hemovascular thiab antioxidant zog.
Thaum ua ntawv thov Glyclazide Canon rau kev kho mob ntawm hom 2 mob ntshav qab zib mellitus, qhov nce siab thaum ntxov nyob rau hauv insulin secretion tau rov qab los hauv kev teb rau cov piam thaj thiab kev nce ntxiv hauv theem ob ntawm insulin secretion. Raws li kev hloov tawm, uas yog vim qhov qhia txog cov piam thaj lossis kev noj zaub mov, muaj qhov nce siab hauv insulin secretion.
Qhov ua haujlwm ntawm gliclazide yog tsom rau txo qis kev pheej hmoo ntawm cov hlab ntsha me, uas tshwm sim vim muaj kev cuam tshuam rau cov txheej txheem uas yuav cuam tshuam nrog kev txhim kho cov teeb meem hauv cov ntshav qab zib mellitus. Cov no suav nrog: ib nrab kev cuam tshuam ntawm platelet adhesion thiab kev sib sau ua ke, qhov txo qis hauv cov ntsiab lus ntawm platelet ua kom muaj lwm yam (thromboxane B2beta-thromboglobulin). Tsis tas li ntawd, Gliclazide Canon cuam tshuam rau kev kho dua tshiab ntawm cov kev ua haujlwm ntawm fibrinolytic ntawm vascular endothelium thiab ib qho kev nce ntxiv ntawm cov nqaij mos plasminogen activator.
Piv rau cov qauv glycemic tswj (raws li cov txiaj ntsig ntawm qhov kev tshawb pom ADVANCE), vim txhim kho glycemic tswj raws li kev tiv thaiv ntev-tso glycazide kev kho mob, tus nqi ntawm HbAlc (glycosylated hemoglobin)
Kev ntsuas rau siv
Cov tshuaj yog npaj rau kev kho mob ntawm qhov tsis yog insulin-mob ntshav qab zib mellitus (hom 2), yog tias kev kho cov khoom noj khoom haus, qhov hnyav thiab lub cev tsis ua kom tshwm sim. Tsis tas li ntawd, cov tshuaj yog tsim nyog rau kev tiv thaiv ntawm kev mob tshwm sim ntawm tus mob ntshav qab zib hom 2 (micro- thiab macro-vascular pathologies), rau kev kho mob latent chav kawm ntawm tus kab mob (latent, nyob rau hauv uas tsis muaj cov lus tshaj tawm txog kev mob ntshav qab zib), nrog kev rog ntawm exogenous tsab cai los.
Kev Sib Sau thiab daim ntawv ntawm kev tso tawm
Cov hauv qab no yog suav nrog tshuaj:
- Nquag: gliclazide 30 lossis 60 mg.
- Ntu: hydroxypropyl methylcellulose, colloidal silicon dioxide, mannitol, E572 (magnesium stearate), hydrogenated zaub roj, microcrystalline cellulose.
Gliclazide canon yog npaj rau kev tswj hwm qhov ncauj. Daim ntawv noj tshuaj: pab txhawb cov ntsiav tshuaj tso tawm. Cov chaw tsim khoom lag luam muaj ntau txoj kev hloov ntau: 30 thiab 60 mg. Cov ntsiav tshuaj yog puag ncig, convex los ntawm 2 sab, dawb (heterogeneous marble xim, muaj ntxhib pub), ntxhiab tsw.
Kho thaj chaw
Tus txheej txheem ntawm kev ua yog txuam nrog cov nyhuv ntawm sulfonylurea derivatives ntawm receptors hauv pancreatic cells-hlwb. Raws li qhov tshwm sim tshwm sim ntawm qib xovtooj ntawm tes, KATF + cov duab raug kaw thiab cov memb-cell daim nyias nyias yog depolarized. Vim yog lub depolarization ntawm cell week, Ca + raws tau qhib, calcium ions nkag rau the-hlwb. Cov tshuaj dej tawm thiab tso rau hauv cov ntshav.
Nyob rau tib lub sijhawm, cov tshuaj maj mam ua rau lub hlwb ntawm cov txiav, ua rau ua xua, plab zom mov ntxiv, ua rau muaj kev muaj ntshav siab qis, thiab lwm yam. Nws ua kom txog thaum lub peev xwm ntawm insulin-hluavtaws pancreatic muaj nuj nqi. Tias yog vim li cas nrog kev siv sijhawm ntev ntawm yeeb tshuaj, nws qhov pib cuam tshuam rau insulin secretion tsawg. Txawm li cas los xij, tom qab kev so nkag mus, kev tawm tsam ntawm β-hlwb rov qab.
Gliclazide canon yog nrawm thiab ua kom tiav los ntawm cov hnyuv. Tom qab noj mov, cov piam thaj nce siab, yog li qhov tseem ceeb ntawm kev tso pa tawm ntawm insulin tshwm sim thaum lub sijhawm no. Kev sib xyaw ua ke ntawm kev siv yeeb tshuaj thiab zaub mov tuaj yeem txo tus nqi ntawm nqus. Kev hem thawj ntau dhau kuj tuaj yeem ua rau qeeb qeeb ntawm qhov nqus thiab qhov no yog vim qhov tseeb tias pathology tau nrog ua kom tsawg dua hauv kev ua haujlwm ntawm lub cev muaj zog ntawm lub plab zom mov.
Cov tshuaj muaj txiaj ntsig pib hauv 2-3 teev tom qab kev coj noj coj ua. Qhov siab tshaj plaws ntawm cov tshuaj nquag hauv cov ntshav tau pom tom qab 7-10 teev. Lub sijhawm ua ntawm - 1 hnub. Nws yog tawm hauv cov zis, ntxiv rau dhau los ntawm cov hnyuv.
Txoj kev ntawm daim ntawv thov
Tus nqi nruab nrab ntawm cov tshuaj yog 60 mg - 150 rubles., 30 mg - 110 rubles.
Cov tshuaj yog tsim rau cov laus xwb. Tsuas tshuaj nyob rau ib hnub - 30-120 mg. Qhov ntau npaum li cas yuav tsum tau sau tseg los ntawm tus kws kho mob koom nrog, coj mus rau hauv tus account theem ntawm tus kab mob, nws cov tsos mob, yoo mov qab zib thiab 2 teev tom qab noj mov, tus neeg mob lub hnub nyoog thiab tus kheej teb rau kev kho. Raws li txoj cai, kev muab tshuaj rau thawj zaug rau kev kho mob ntshav qab zib tsis ntau tshaj 80 mg, thiab rau kev tiv thaiv lossis kho kev kho mob - 30-60 mg.
Yog tias nws tau tshaj tawm tias kev noj tshuaj tsis zoo txaus, ces nws yog maj mam nce ntxiv. Ib qho ntxiv, txhua qhov kev hloov pauv ntawm cov txheej txheem kev kho mob yuav tsum tau ua kom tsis pub dhau ob lub lis piam txij li lub sijhawm pib kev kho mob. Yog tias ib koob lossis ob zaug tshuaj ploj, nws tsis tuaj yeem ua kom ntau ntxiv ntawm cov koob tshuaj tom qab.
Nws raug nquahu kom noj cov tshuaj txhua hnub 1 zaug los ntawm kev nqos tag nrho cov ntsiav tshuaj. Txhawm rau tiv thaiv cov tshuaj sib xyaw ua ke thiab cov khoom noj, nws yog qhov zoo uas yuav tau siv cov tshuaj ib nrab ib teev ua ntej ib pluas noj.
Thaum cev xeeb tub thiab pub niam mis
Cov nyhuv ntawm cov tshuaj nyob rau hauv chav ntawm cev xeeb tub thiab tus me nyuam hauv plab tsis tau to taub zoo. Yog li, cov lus qhia rau kev siv txwv tsis pub siv tshuaj thaum lub sijhawm coj menyuam thiab HB.
Cov Kev Tsis Txaus Ntseeg thiab Kev Ceev Faj
Pub nkag yog contraindicated nyob rau hauv lub xub ntiag ntawm cov mob no:
- mob ntshav qab zib insulin-hom mob ntshav qab zib hom (hom 1),
- ketoacidosis, mob qa,
- mob siab, mob raum,
- lub sijhawm ntawm gestation, GV,
- cov me nyuam muaj hnub nyoog
- hypersensitivity rau yeeb tshuaj nyob rau hauv cov tshuaj ntawm cov tshuaj.
Kev mob ntshav qab zib yog nrog los ntawm kev poob qis hauv kev xav, kiv taub hau, ntsig txog qhov txawv txav, thiab lwm cov tsos mob. Tus kws kho mob ntshav qab zib yuav tsum paub txog qhov ua tau ntawm cov kab mob no thiab ceev faj thaum koom nrog kev ua si uas yuav tsum muaj kev cuam tshuam psychomotor ceev (piv txwv li tsav tsheb).
Hla kev sib txuam yeeb tshuaj
Cov nyhuv ntawm cov tshuaj tuaj yeem ua kom zoo dua los ntawm lwm cov tshuaj, uas ua rau muaj peev xwm tsim muaj ntshav qab zib tsawg. Glyclazide Canon yog contraindicated ua ke nrog Miconazole. Nws tsis pom zoo kom sib xyaw cov kev sib xyaw nrog phenylbutazone, ethanol.
Kev sib xyaw ntawm cov tshuaj nrog rau lwm cov kab mob hypoglycemic (insulin, acarbose), beta-blockers, ACE inhibitors, calcium npaj, β-blockers yuav tsum ceev faj, vim tias txhim kho cov nyhuv hypoglycemic.
Cov tshuaj hauv qab no ua rau lub cev tsis zoo ntawm cov tshuaj:
- Danazole - muaj cov nyhuv ntshav qab zib,
- Chlorpromazine - ua rau cov ntshav qab zib ntau ntau, txo cov tshuaj insulin kom tsawg.
Phiv thiab haus tshaj
Gliclazide canon tau pom zoo los ntawm cov neeg mob. Cov tshuaj yog ntau dua li thawj thawj zaug sulfonylureas. Qhov no tso cai rau kev siv cov tshuaj qis dua ntawm cov tshuaj, uas txo qhov ntxim nyiam ntawm qhov tshwm sim tsis zoo tom qab siv.
Tab sis nrog siv ntev, cov kev mob tshwm sim tuaj yeem tsim. Ib qho ntawm cov kev mob tshwm sim tsis zoo tshaj plaws yog kev txhim kho hypoglycemia, tshwj xeeb tshaj yog nyob rau cov neeg laus dua 50 xyoo, uas muaj qhov tshwm sim:
- Ib txhij tuav tswj ntawm ntau cov tshuaj.
- Lub cev yuag.
- Tsis noj mov txaus.
- Kev haus dej haus cawv.
- Ua txhaum ntawm ob lub raum, mob siab, thiab lwm yam.
Kuj, tawm tsam keeb kwm yav dhau los ntawm kev noj mov tsis tu ncua, cov neeg mob feem ntau muaj qhov nce siab, uas ua rau lub hauv paus poob phaus ntxiv. Txhawm rau tiv thaiv qhov hnyav nce, nws pom zoo kom ua raws li kev noj zaub mov hypocaloric.
Lwm qhov tsis zoo ntawm kev noj kuj suav nrog:
- Lub plab zom mov tsis zoo: xeev siab, raws plab, mob plab / mob plab, ntuav.
- Ua xua (tawm pob, khaus khaus ntawm daim tawv nqaij).
- CNS: kev voos, insomnia, kev nyuaj siab, ua pa nyuaj, ua rau tsis muaj zog, tsis meej pem, maj mam, ntxhov siab, ntxhov siab, ntshai.
- Cov hlab ntsha, lub siab: mob taub hau, nce ntshav siab, ntshav ntuav.
- Mob siab, mob plab biliary: cholestatic jaundice, kab mob siab.
- Pom qhov muag tsis pom kev, pallor ntawm daim tawv nqaij.
Cov kev mob tshwm sim no muaj tsawg heev, hauv 1-2% ntawm cov neeg mob. Yog tias muaj qhov tshwm sim sab saud, kev tswj hwm yuav tsum tsis ua mus ntxiv.
Nws raug nquahu kom tsis txhob haus ntau dhau ntawm cov tshuaj ntawm cov tshuaj, li kev pheej hmoo ntawm cov ntshav qog ntshav nce zuj zus, thiab cov kev hloov kho tsis tu ncua ntawm β-hlwb depletes lawv. Muaj qhov ntxim nyiam ntawm kev txhim kho lub neej hnyav ntawm cov ntshav qog ntshav qab zib, nce mus rau hauv lub cev ntawm cov hlab ntsha, qaug dab peg, tsis nco qab. Hauv qhov no, yuav tsum tau pw hauv tsev kho mob sai thiab muaj kev pabcuam tsim nyog ntawm cov neeg ua haujlwm kho mob.
Kev siv tshuaj ntau dhau yog ua los ntawm kev noj cov ntshav qab zib lossis los ntawm kev txhaj tshuaj rau hauv / hauv (50%, 50 ml), nrog kev o ntawm lub hlwb - hauv / hauv Mannitol. Ib qho ntxiv, kev saib xyuas kab ke hauv theem ntawm cov piam thaj hauv 2 hnub tom ntej no yuav tsum muaj.
Chaw tsim tshuaj paus: Lab. Servier Kev Lag Luam, Fabkis.
Tus nqi nruab nrab: 310 RUB
Cov tshuaj tseem ceeb: gliclazide. Daim ntawv qhia cov ntsiav tshuaj.
Qhov zoo: tsis tshua muaj cov kev mob tshwm sim (li ntawm 1% ntawm cov neeg mob ntshav qab zib), kev ua haujlwm siab, maj mam txo cov piam thaj, txo cov ntshav txhaws, cov lus qhia yooj yim rau kev siv.
Qhov tsis zoo: tus nqi siab, maj mam depletes β-hlwb.
Chaw tsim tshuaj paus: Ranbaxi Laboratories Ltd., Is Nrias teb.
Tus nqi nruab nrab: 200 txhuam Cov tshuaj tseem ceeb: gliclazide. Daim ntawv qhia cov ntsiav tshuaj.
Qhov zoo: ua hauj lwm zoo rau cov ntshav qabzib, qhia tau rau lub cev in-hlwb rov qab rau sulfonylureas thawj tiam, txo qhov ntxim nyiam ntawm thrombosis.
Qhov tsis zoo: nrhiav tsis yooj yim hauv cov chaw muag tshuaj; kev siv tsis tu ncua maj mam ua rau kev tsim cov tshuaj tiv thaiv ntshav qab zib kom tsis txhob muaj kab mob ntshav qab zib.
Tso tawm daim ntawv, muaj pes tsawg leeg thiab ntim khoom
Cov lus qhia uas twb muaj lawm rau kev siv Canon Glyclazide qhia tias nws muaj rau pawg tshuaj uas txo cov ntshav qab zib, kev coj ntawm qhov ncauj thiab qhov tseeb nws tau muaj nyob hauv qeb ntawm sulfonylurea derivatives ntawm lub cim thib ob. Nws muaj cov txheej txheem ntsiav tshuaj duab, convex ntawm ob sab, dawb. Raws li kev txheeb xyuas ntawm Glyclazide Canon, lawv tau tus cwj pwm los ntawm lub teeb taws kub taws. Ib qho tshwj xeeb ntawm cov ntsiav tshuaj yog qhov tso tawm ntev, uas txhais tau hais tias lawv muaj qhov txo qis thiab zaus ntawm cov koob tshuaj, tab sis muaj qhov cuam tshuam ntev. Lub ntsiab lus tseem ceeb yog gliclazide hauv ib ntim ntawm 30 mg thiab 60 mg. Cov npe ntawm cov khoom siv ntxiv tau nthuav tawm los ntawm mannitol, magnesium stearate, colloidal silicon dioxide, microcrystalline cellulose. Gliclazide Canon tus nqi hauv Moscow thiab lwm thaj chaw zoo heev rau cov pej xeem niaj hnub ua tiav cov txheej txheem siv cov tshuaj no.
Pharmacological kev txiav txim
Cov haujlwm ua haujlwm tseem ceeb ntawm Canon Gliclazide yog ntxias kev tsim cov tshuaj insulin beta hlwb hauv cov txiav ua ke. Cov tshuaj kuj tseem yuav ua rau kom muaj qhov tsis txaus sab hauv cov ntaub so ntswg. Uas yog, nws yog lub luag haujlwm rau kev txhawb lub zog ntawm cov enzymes hauv lub hlwb. Nws luv luv lub sij hawm ua ntu zus nruab nrab ntawm kev noj mov thiab pib ntawm kev tawm ntawm cov kua dej. Nws cuam tshuam qhov rov pib dua ntawm qhov ua tiav thaum ntxov ntawm cov tshuaj insulin tso tawm thiab qhov txo qis hauv lub sijhawm postprandial ncov ntawm hyperlycemia. Glyclazide Canon pab txo cov platelet sib sau ua ke thiab txhawm rau txhawm rau, ua kom qeeb ntawm kev tsim cov parietal thrombi, thiab txhim kho kev ua vascular fibrinolytic. Lub luag haujlwm rau cov normalization ntawm vascular permeability. Nws kuj tseem muaj cov khoom siv los tiv thaiv atherogenic, uas tau tshwm sim hauv kev txo cov ntshav hauv cov ntshav siab, nce ntxiv ntawm kev txuam nrog HDL-C, thiab cov tsawg ntawm cov dawb radicals uas twb muaj lawm. Tiv thaiv atherosclerosis thiab microthrombosis, lawv tsim. Txo vascular ua rau muaj kev nyuaj siab rau adrenaline thiab muaj cov txiaj ntsig zoo ntawm kev txhim kho microcirculation. Kev siv lub sijhawm ntev ntawm Canon Glyclazide txo cov proteinuria hauv kev mob ntshav qab zib nephropathy. Kev tsis haum ntawm cov tshuaj los ntawm lub plab zom mov tshwm sim sai dua li ntawm Canon Gliclazide analogues. Kev tshem tawm yog tshwm sim los ntawm lub raum nrog kev pab ntawm metabolites, thiab kwv yees li 1% los ntawm kev tso zis.
Gliclazide Canon tau tsim rau cov neeg mob uas tau pom muaj nyob ntawm hom 2 mob ntshav qab zib mellitus, kom lub cev nyhav dua li qub, tseem yuav ua kom lub cev muaj zog thiab muaj zog, thiab thaum lub sijhawm no uas cov zaub mov tsis zoo tsis muaj txiaj ntsig. Haum raws li prophylaxis tiv thaiv exacerbations ntawm ntshav qab zib mellitus: yuav kom tiv thaiv kev pheej hmoo ntawm microvascular exacerbations, tiv thaiv macrovascular exacerbations - mob stroke thiab lub plawv nres, los ntawm kev txhim kho glycemic yoos.
Sab sij huam
Cov kev mob tshwm sim los ntawm kev siv cov tshuaj yog: - hypoglycemic kab mob tshwm sim los ntawm kev noj zaub mov tsis zoo thiab kev noj zaub mov tsis raug, - mob taub hau, - qaug zog, - nce tawm hws, - lub plawv dhia ceev, - qaug zog thiab tsaug zog, - ntshav siab, - lub ntsej muag ntawm kev ntxhov siab ntau dhau, - muaj teeb meem nrog pw tsaug zog, - lub xeev ntawm arrhythmia, - nervousness thiab npau taws, - cov tsos ntawm cov teeb meem nrog cov hais lus apparatus thiab qhov tsis zoo ntawm lub suab pom, - maj mam rov qab los, - ntxhov siab, - kev nyuaj siab lub xeev, - tshee thaum kawg styah - ntog mus rau hauv ib tug coma, - tsaus muag, - qaug dab peg, - qhov teeb meem ntawm helplessness - cov tsis muaj ntawm nws tus kheej-tswj - lub rov tshwm sim ntawm bradycardia. Lub plab zom mov ua haujlwm nrog cov tsos mob ua kom raws plab, ntuav, mob plab, muaj teeb meem nrog quav, qee zaum muaj kev ua haujlwm tsis zoo ntawm lub siab.Nrog rau cov kab mob siab thiab mob cholestatic, muaj qhov mob hnyav sai sai yuav tsum tshem tawm txoj kev kho mob, nce qhov kev hloov pauv ntawm qhov mob hepatic transaminases, alkaline phosphatase. Cov plab hnyuv siab raum ua lub luag haujlwm rau hematopoiesis muab cov taw qhia kev mob siab rau cov hlwb pob txha txha ntshav. Kev ua xua rau qhov kev ua xua yog tshwm sim los ntawm qhov tshwm sim ntawm khaus thiab tawm pob rau ntawm lub cev, erythema thiab urticaria. Sulfonylurea derivatives muaj kev cuam tshuam los ntawm vasculitis, erythropenia, hemolytic anemia, pancytopenia, agranulocytosis, thiab ua rau lub siab ua haujlwm tsis zoo, uas tuaj yeem ua rau tuag taus.
Noj ntau dhau
Nyob rau hauv ib qho xwm txheej ntawm kev tso cai ntau tshaj ntawm kev tso cai pom zoo ntawm Canon Glyclazide, muaj qhov ntxim nyiam ntawm tus mob hypoglycemic, tus mob tsaus muag thiab muaj kev pheej hmoo ntawm poob rau hauv lub ntsej muag hypoglycemic. Rau kev kho mob ntawm cov neeg mob uas paub meej, nws yog ib qho tsim nyog yuav tsum tau noj qab zib sab hauv. Tseem muaj kev pheej hmoo ntawm qaug dab peg, cuam tshuam los ntawm cov paj hlwb, los ntawm qhov tshwm sim ntawm ib tus mob hypoglycemic lub xeev. Qhov xwm txheej no yuav tsum muaj lus teb sai los ntawm cov kws kho mob thiab kho tsev kho mob sai. Raws li qhov kev xav lossis paub txog qhov ua kom lub cev tsis tsaug zog, qhov yuav tau txhaj tshuaj 40% nyob rau hauv cov dej ntawm 50 ml yog qhov yuav tsum tau ua sai, tom qab ntawd, txhawm rau kom muaj cov suab thaj txaus, cov dej qab zib 5% dextrose yog txhaj rau qhov poob lawm. Ob peb teev tom qab no tom qab tus neeg raug tsim txom los rau nws tus kheej, txhawm rau tiv thaiv kom tsis txhob rov muaj kab mob ntshav qab zib, nws yuav tsum pub zaub mov rau nws noj uas muaj nplua nuj nyob hauv cov zom zaub kom yooj yim. Txog 48 teev ntxiv, kom tus neeg mob saib xyuas lawv thiab saib xyuas tus neeg mob cov ntshav cov ntshav qabzib. Txhua qhov kev soj ntsuam ntxiv los ntawm cov kws kho mob nyob ntawm nws lub xeev kev noj qab haus huv. Nyob rau hauv qhov xwm txheej zoo sib xws, raws li kev khi ntawm gliclazide rau cov ntshav plasma protein, kev lim ntshav yuav tsis muaj kev tiv thaiv zoo.
Yeeb tshuaj sib cuam tshuam
Kev sib xyaw ntawm Canon Glyclazide nrog cov tshuaj anticoagulants yog qhov teeb meem tseem ceeb, vim tias cov tshuaj txhim kho lawv cov nyhuv, uas yuav tsum muaj kev kho kom haum. Miconazole nias rau exacerbate hypoglycemic lub xeev. Ua ntej thiab tom qab phenylbutazone, nws yog qhov yuav tsum tau soj ntsuam thiab tshawb xyuas qib ntawm cov piam thaj hauv cov ntshav thiab ua cov kev kho rau cov nyiaj glyclazide noj, vim qhov tseeb nws pab txhawb kom cov kev ua haujlwm ntawm cov nyhuv hypoglycemic. Cov tshuaj noj, nrog lub xub ntiag ntawm ethyl cawv nyob rau hauv kev tsim qauv, tuaj yeem txhim kho kev mob ntshav qab zib, thiab txhim kho hypoglycemic coma. Kev sib xyaw nrog Canon Glyclazide nrog cov tshuaj ntawm nws pab pawg (insulin, acarbose), beta-blockers, fluconazole, monoamine oxidase inhibitors, H2-histamine receptor blockers, tshuaj tsis-steroidal los tiv thaiv cov tshuaj, sulfonamides exacerbate cov kev tiv thaiv hypoglycemic thiab hypoglycemic thiab aggravations. Diabetogenic nyhuv muaj danazol. Txo kev tsim ntawm cov tshuaj insulin thiab nws cov kev txuam nrog hauv cov ntshav ua rau lub siab ntawm chlorpromazine. Kev tswj hwm ntawm terbutaline los ntawm cov leeg, salbutamol thiab ritodrine nce thiab ntau ntxiv cov piam thaj. Yuav tsum muaj kev tswj hwm nws cov qib thiab hloov pauv hauv chav raug xaiv los ntawm kev kho rau tshuaj insulin.
Cov lus qhia tshwj xeeb
Cov txheej txheem kev kho mob nrog Glyclazide Canon yog nrog kev saib xyuas ntawm cov zaub mov tsis muaj calorie, kev noj zaub mov zoo noj qab haus huv nrog kev suav nrog kev noj tshais thiab cov naj npawb txaus siab ntawm cov khoom noj carbohydrates. Raws li kev tswj hwm ntawm cov neeg ua haujlwm sib luag ntawm sulfonylurea derivatives, hypoglycemia yog qhov muaj peev xwm heev ntawm kev tsim kho, qee zaum tsis dhau yam tsis muaj cov kua nplaum thiab kev tso kawm hauv tsev kho mob. Txuas mus rau kev haus cawv, noj ntau ntau ntawm cov kab mob hypoglycemic nyob rau hauv thaum uas tig mus, kev ua haujlwm ntau dhau ntawm lub cev tuaj yeem ua rau lub cev tsis muaj ntshav qab zib. Kev xav ntawm lub siab ntsws, kev tshuaj xyuas cov khoom noj xav tau koob tshuaj hloov kho tshuaj. Kev raug mob ntawm lub cev, muaj mob hnyav ntawm lub cev kub hnyiab, kab mob tshwm sim los ntawm ntau yam kab mob thiab xav tau kev phais mob, uas kev teem sij hawm ntawm cov tshuaj insulin yog ua tau, yog qhov tseem ceeb uas yuav tsum tshem tawm ntawm kev noj Glyclazide Canon. Cov txheej txheem ntawm kev kho nrog cov tshuaj muaj peev xwm cuam tshuam rau kev xav thiab teb sai, yog li rau ib lub sijhawm koj yuav tsum tso tseg nyob tom qab lub log thiab cov txheej txheem ua haujlwm uas xav tau siab tshaj plaws. Cov txheej txheem kev kho yuav tsum tau nrog cov kev txiav txim siab ib theem ntawm cov ntshav qabzib thiab glycosylated hemoglobin hauv cov ntshav, thiab nws cov concentration hauv cov zis.
Glyclazide Canon
Kev Txhawb Nqaij Tso Tawm dawb lossis yuav luag dawb, puag ncig, biconvex, nrog kev pheej hmoo, me ntsis marbling raug tso cai.
Cov zam: hypromellose (hydroxypropyl methylcellulose) - 100 mg, colloidal silicon dioxide - 7 mg, mannitol - 80 mg, magnesium stearate - 3.6 mg, hydrogenated zaub roj - 7.2 mg, microcrystalline cellulose - 102,2 mg.
10 Pcs - blister pob khoom (3) - pob ntawv ntawm cardboard. 10 pcs. - blister pob khoom (6) - pob ntawv ntawm cardboard. 15 pcs. - blister packagings (2) - pob ntawv los ntawm cardboard.
15 Pcs. - hlwv pob (4) - pob khoom los ntawm cardboard.
Cov Tshuaj Pharmacokinetics
Tom qab kev tswj hwm ntawm qhov ncauj, nws nrawm los ntawm lub plab zom mov. Cmax hauv cov ntshav tau mus txog kwv yees li 4 teev tom qab noj ib koob ntawm 80 mg.
Plasma protein khi yog 94.2%. Vd - txog 25 l (0.35 l / kg lub cev hnyav).
Nws yog metabolized hauv lub siab nrog kev tsim ntawm 8 metabolites. Lub ntsiab metabolite tsis muaj qhov teebmeem hypoglycemic, tab sis muaj cov nyhuv ntawm microcirculation.
T1 / 2 - 12 teev .Nws yog txau feem ntau los ntawm lub raum ua cov tshuaj metabolites, tsawg dua 1% yog pom hauv cov zis tsis hloov pauv.
Hom 2 mob ntshav qab zib mellitus nrog cov tsis muaj txiaj ntsig ntawm kev kho zaub mov noj, ua kom lub cev thiab yuag poob.
Kev tiv thaiv ntawm cov teeb meem ntawm hom 2 mob ntshav qab zib mellitus: txo kev pheej hmoo ntawm microvascular (nephropathy, retinopathy) thiab mob macrovascular (myocardial infarction, stroke).
Glyclazide MV 30 mg thiab MV 60 mg: cov lus qhia thiab tshuaj xyuas rau cov neeg mob ntshav qab zib
Gliclazide MV yog ib hom tshuaj kho mob ntshav qab zib hom 2 ntau tshaj plaws. Nws yog rau cov tiam thib ob ntawm sulfonylurea kev npaj thiab tuaj yeem siv tau ob qho tib si hauv tshuaj tua kab mob thiab nrog rau lwm cov kua qab zib thiab cov tshuaj insulin.
Ntxiv rau qhov ntxim rau cov ntshav qab zib, gliclazide muaj cov txiaj ntsig zoo ntawm qhov sib xyaw ntawm cov ntshav, txo qis oxidative kev nyuaj siab, txhim kho microcirculation. Cov tshuaj tsis yog yam nws tsis muaj: nws ua rau nce phaus, nrog rau siv ntev, cov ntsiav tshuaj poob lawv qhov kev ua tau zoo. Txawm hais tias noj tshuaj ntau dhau me ntsis ntawm gliclazide yog qhov ua haujlwm nrog kev mob ntshav qab zib, qhov kev pheej hmoo yog tshwj xeeb hauv cov laus.
Cov ntaub ntawv dav dav
Cov ntawv pov thawj rau npe Gliclazide MV yog tawm los ntawm tuam txhab Lavxias Atoll LLC. Cov tshuaj yeeb yaj kiab hauv qab ntawv cog lus yog tsim los ntawm Samara lub tuam txhab tshuaj Ozone. Nws ua thiab ntim cov ntsiav tshuaj, thiab tswj lawv qhov zoo.
Gliclazide MV tsis tuaj yeem hu ua cov tshuaj hauv tsev, vim tias cov tshuaj yeeb tshuaj rau nws (tib yam glyclazide) tau yuav hauv Suav teb. Dua li ntawm qhov no, tsis muaj dab tsi tsis zoo tuaj yeem hais txog qhov zoo ntawm cov tshuaj.
Raws li cov kws kho mob ntshav qab zib, nws tsis muaj qhov phem tshaj li Fab Kis Diabeton nrog tib yam.
Cov kab lus ncua hauv MV nyob rau hauv lub npe ntawm cov tshuaj qhia tau hais tias cov tshuaj nquag hauv nws yog hloov kho, lossis ntev ntev, tso tawm.
Glyclazide tawm cov ntsiav tshuaj thaum lub sijhawm thiab hauv qhov chaw zoo, uas ua kom paub meej tias nws tsis nkag mus rau hauv cov hlab ntshav tam sim ntawd, tab sis hauv feem me me. Vim tias qhov no, qhov kev pheej hmoo ntawm qhov tsis tsim nyog raug txo qis, cov tshuaj muaj peev xwm coj tau tsawg dua.
Yog tias tus qauv ntawm cov ntsiav tshuaj raug yuam, nws txoj haujlwm ntev yog ploj, yog li ntawd, cov lus qhia rau kev siv tsis pom zoo kom ntov nws.
Glyclazide muaj nyob hauv cov npe tshuaj tseem ceeb, yog li cov kws kho mob endocrinologist muaj lub sijhawm los sau nws rau cov ntshav qab zib pub dawb. Feem ntau cov feem ntau, raws li daim ntawv sau tshuaj, nws yog qhov kev nyeg MV Gliclazide uas yog ib qho piv txwv ntawm cov Diabeton qub.
Cov tshuaj ua haujlwm li cas?
Txhua tus gliclazide daig nyob rau hauv cov hnyuv tau nqus rau hauv cov ntshav thiab muaj qhov khi rau nws cov protein. Feem ntau, cov piam thaj nkag mus hauv beta hlwb thiab txhawb cov neeg tshwj xeeb uas ua rau muaj qhov tso tawm ntawm cov kua dej. Glyclazide ua haujlwm los ntawm tib lub hauv paus ntsiab lus, artificially provoking lub synthesis ntawm yam tshuaj.
Cov nyhuv ntawm cov kua dej hauv kev tsim tawm tsis tas rau cov nyhuv ntawm MV Glyclazide. Cov tshuaj muaj peev xwm ntawm:
- Txo cov tshuaj tiv thaiv insulin. Cov txiaj ntsig zoo tshaj plaws (nce insulin rhiab heev los ntawm 35%) raug pom hauv cov leeg nqaij.
- Txo cov synthesis ntawm cov piam thaj los ntawm lub siab, yog li ntawd ib txwm ua rau nws qib sai.
- Tiv thaiv kom ntshav txhaws.
- Pab txhawb ua ke ntawm cov tshuaj nitric oxide, uas koom nrog tswj kev kub siab, txo kev mob, thiab txhim kho cov ntshav rau cov ntaub so ntswg.
- Ua haujlwm li tshuaj tiv thaiv kab mob.
Daim ntawv tso tawm thiab ntau npaum li cas
Hauv cov ntsiav tshuaj Gliclazide MV yog 30 lossis 60 mg ntawm cov tshuaj nquag.
Cov khoom xyaw pabcuam yog: cellulose, uas yog siv los ua tus neeg saib xyuas bulking, silica thiab magnesium stearate li emulsifiers.
Cov ntsiav tshuaj ntawm cov xim dawb lossis qab zib, tso rau hauv hlwv ntawm 10-30 pieces. Hauv ib pob ntawm 2-3 blisters (30 lossis 60 ntsiav tshuaj) thiab cov lus qhia. Glyclazide MV 60 mg tuaj yeem faib ua ib nrab, rau qhov no muaj kev pheej hmoo ntawm cov ntsiav tshuaj.
Cov tshuaj yuav tsum haus cawv thaum noj tshaisCov. Gliclazide ua haujlwm txawm hais tias muaj suab thaj hauv cov ntshav. Yog li hais tias hypoglycemia tsis tshwm sim, tsis muaj zaub mov noj yuav tsum raug hla, txhua ntawm lawv yuav tsum muaj kwv yees li ntawm cov nyiaj carbohydrates. Nws raug nquahu kom noj txog li 6 zaug hauv ib hnub.
Cov cai xaiv:
Hloov los ntawm ib txwm Gliclazide. | Yog tias cov ntshav qab zib tau noj yav tas los tsis siv tshuaj ntau dua, qhov tshuaj ntawm cov tshuaj no rov qab tau suav: Gliclazide 80 yog muaj sib npaug rau Gliclazide MV 30 mg hauv cov ntsiav tshuaj. |
Pib siv koob tshuaj, yog tias cov tshuaj raug pom zoo rau thawj zaug. | 30 mg Txhua tus neeg mob ntshav qab zib pib nrog nws, tsis hais hnub nyoog li cas thiab glycemia. Tag nrho lub hlis tom ntej, nws yog txwv tsis pub nce cov tshuaj ntau npaum li cas kom muab lub sijhawm ntev rau cov neeg ua haujlwm kom tau siv los ua haujlwm tshiab. Qhov kev zam tsuas yog tsim rau cov neeg mob ntshav qab zib nrog cov ntshav qab zib heev, lawv tuaj yeem pib nce ntxiv tom qab 2 lub lis piam. |
Qhov kev txiav txim ntawm cov tshuaj ntau dua. | Yog tias 30 mg tsis txaus los kho cov ntshav qab zib, cov koob tshuaj tau raug nce mus rau 60 mg thiab ntxiv mus. Txhua qhov kev nce ntxiv hauv cov tshuaj yuav tsum yog tsawg kawg 2 lub lis piam tom qab. |
Qhov siab tshaj plaws ntau npaum li cas. | 2 tab. Gliclazide MV 60 mg lossis 4 txog 30 mg. Tsis txhob ntau tshaj nws nyob rau hauv txhua rooj plaub. Yog tias nws tsis txaus rau cov piam thaj ib txwm, lwm yam kab mob kev tiv thaiv kab mob tau ntxiv rau kev kho mob. Cov kev qhia tso cai rau koj los ua ke gliclazide nrog metformin, glitazones, acarbose, insulin. |
Qhov siab tshaj plaws qhov siab yuav txo qhov tus mob hypoglycemia. | 30 mg Cov pab pawg muaj suav nrog cov neeg mob endocrine thiab cov kab mob plawv heev, nrog rau cov neeg uas noj glucocorticoids ntev. Glyclazide MV 30 mg hauv cov ntsiav tshuaj yog qhov zoo dua rau lawv. |
Cov lus qhia ntxaws ntxiv rau siv
Raws li kev pom zoo hauv chaw kho mob pom zoo los ntawm Ministry of Health ntawm Lavxias Federation, gliclazide yuav tsum tau sau tseg los siv tshuaj insulin secretion. Qhov kev xav, qhov tsis muaj ntawm ib tus kheej lawm yuav tsum tau paub tseeb los ntawm kev kuaj mob ntawm tus neeg mob. Raws li kev txheeb xyuas, qhov no tsis tas yuav tshwm sim. Cov kws kho mob thiab cov kws txawj endocrinologists muab tshuaj "los ntawm qhov muag".
Raws li qhov tshwm sim, ntau tshaj qhov xav tau ntawm cov tshuaj insulin yog qhov zais cia, tus neeg mob ib txwm xav noj, nws qhov hnyav nce zuj zus, thiab cov nyiaj them rau ntshav qab zib tseem tsis txaus. Tsis tas li ntawd, beta hlwb nrog hom kev ua haujlwm no raug rhuav tshem nrawm dua, uas txhais tau hais tias tus kabmob mus rau theem tom ntej.
Yuav ua li cas zam kom dhau qhov kev rau txim:
- Pib nruj me ntsis cov kab mob rau cov pluas noj rau cov neeg mob ntshav qab zib (cov lus 9, cov nyiaj uas tau tso cai ntawm carbohydrates yog txiav txim los ntawm tus kws kho mob lossis tus neeg mob nws tus kheej raws li glycemia).
- Tshaj tawm cov kev nquag hauv kev ua txhua hnub.
- Qhov hnyav ua rau qhov qub. Rog dhau heev lawm ua rau cov ntshav qab zib.
- Haus dej qabzib lossis nws cov tshuaj noj. Cov tshuaj noj zoo yog 2000 mg.
Thiab tsuas yog yog hais tias cov kev ntsuas no tsis txaus rau ib txwm qab zib, koj tuaj yeem xav txog gliclazide. Ua ntej pib txoj kev kho mob, nws tsim nyog ntsuas kev soj ntsuam rau C-peptide lossis insulin kom paub tseeb tias qhov sib xyaw ntawm cov tshuaj hormones yog qhov tiag tiag.
Thaum glycated hemoglobin siab dua 8.5%, MV Gliclazide tuaj yeem muab nrog rau kev noj haus thiab metformin ib ntus, kom txog thaum muaj ntshav qab zib tau them rov qab. Tom qab ntawd, qhov teeb meem ntawm kev tshem tawm cov tshuaj yog tus kheej tau txiav txim siab.
Yuav noj li cas thaum cev xeeb tub
Cov lus qhia rau kev siv txwv tsis pub kho nrog Gliclazide thaum cev xeeb tub thiab lactation. Raws li FDA kev faib tawm, cov tshuaj yog rau cov chav kawm C. Qhov no txhais tau tias nws tuaj yeem cuam tshuam tsis zoo rau kev loj hlob ntawm tus me nyuam hauv plab, tab sis tsis ua rau muaj qhov tsis zoo thaum yug los. Gliclazide muaj kev nyab xeeb dua los hloov nrog cov tshuaj insulin ua ntej cev xeeb tub, hauv cov xwm txheej hnyav - thaum pib.
Qhov tau los ntawm kev pub mis niam nrog gliclazide tsis tau sim. Muaj pov thawj tias sulfonylurea kev npaj tau tuaj yeem mus rau hauv cov mis thiab ua rau cov ntshav qab zib hauv cov menyuam mos, yog li lawv qhov kev siv thaum lub sijhawm no raug txwv tsis pub siv.
Rau leej twg Glyclazide MV yog contraindicated
Cov khoom sib dhos raws li cov lus qhia | Vim li cas rau qhov txiav npluav |
Hypersensitivity rau gliclazide, nws cov analogues, lwm yam sulfonylurea npaj. | Muaj feem ntau ntawm anaphylactic kev tsis haum. |
Hom 1 Ntshav Qab Zib, pancreatic resection. | Thaum tsis muaj cov beta hlwb, insulin hluavtaws tsis tau. |
Mob ketoacidosis, mob heev ceev heev. | Tus neeg mob xav tau kev pab ceev. Tsuas yog cov tshuaj insulin tuaj yeem muab nws. |
Hlob, mob siab. | Muaj kev pheej hmoo siab ntawm hypoglycemia. |
Kev kho mob nrog miconazole, phenylbutazone. | |
Haus cawv. | |
Cev xeeb tub, HB, menyuam hnub nyoog. | Tsis muaj cov kev tshawb fawb tsim nyog. |
Dab tsi tuaj yeem hloov tau
Lavxias teb sab gliclazide yog qhov pheej yig, tab sis zoo tshuaj, tus nqi ntawm ntim ntawm Gliclazide MV (30 mg, 60 daim) yog txog 150 rubles. Hloov nws nrog analogues yog tsuas yog tias cov ntsiav tshuaj li ib txwm tsis tau muag.
Tus tshuaj yog Diabeton MV, txhua lwm yam tshuaj nrog tib yam muaj pes tsawg leeg, suav nrog Gliclazide MV yog cov tshuaj generics, lossis luam tawm. Tus nqi ntawm Diabeton yog kwv yees li 2-3 zaug siab dua li nws cov generics.
Glyclazide MV analogues thiab hloov pauv ua npe rau hauv Lavxias Federation (tsuas yog hloov kho tau npaj los qhia tau tias muaj):
- Glyclazide-SZ uas ua los ntawm Severnaya Zvezda CJSC,
- Golda MV, Pharmasintez-Tyumen,
- Gliclazide Canon los ntawm Canonpharm Ntau Lawm,
- Glyclazide MV Tus Kws Kho Mob, Pharmstandard-Tomskkhimfarm,
- Diabetalong, chaw tsim tshuaj paus ntawm MS-Vita,
- Gliklada, Krka,
- Glidiab MV los ntawm Akrikhin,
- Diabefarm MV Cov Tshuaj Ntau Lawm.
Tus nqi ntawm analogues yog 120-150 rubles rau ib pob. Gliklada ua nyob rau hauv Slovenia yog cov tshuaj kim tshaj plaws los ntawm cov npe no, pob ib nqi txog 250 rubles.
Ntshav Qab Zib Kev Ntsuam Xyuas
Txheeb xyuas los ntawm Sergei, 51 xyoo. Mob ntshav qab zib mellitus rau yuav luag 10 xyoo. Tsis ntev los no, cov piam thaj tau mus txog 9 thaum sawv ntxov, yog li Glyclazide MV 60 mg tau raug xaj. Koj yuav tsum tau haus nws nrog lwm cov tshuaj, Metformin Canon.
Ob qho tshuaj thiab noj zaub mov noj tau qhov txiaj ntsig zoo, cov ntshav sib xyaw ua kom rov zoo li qub hauv ib lub lis piam, ib hlis tom qab ntawd tu tsis taus lawm qhov txhais taw. Muaj tseeb, tom qab txhua txhaum cai ntawm kev noj zaub mov, qab zib nce ceev ceev, tom qab ntawd maj mam poob qis dua ib hnub. Tsis muaj kev mob tshwm sim, txhua yam zoo tiv thaiv.
Tshuaj muaj pub dawb tsis tas them nyiaj hauv chaw kho mob, tab sis txawm tias koj yuav los ntawm koj tus kheej, nws tsis muaj nqi. Tus nqi ntawm Gliclazide yog 144, Metformin yog 150 rubles. Txheeb xyuas los ntawm Elizabeth, hnub nyoog 40 xyoo. Glyclazide MV pib haus ib hlis dhau los, tus kws kho mob endocrinologist tau ntxiv rau Siofor, thaum qhov kev soj ntsuam pom yuav luag 8% ntawm glycated hemoglobin.
Kuv tsis tuaj yeem hais dab tsi tsis zoo txog cov nyhuv, nws tau txo suab thaj sai.Tab sis cov kev mob tshwm sim kiag li ua rau kuv tsis muaj sijhawm los ua haujlwm. Kuv txoj haujlwm muaj kev sib txuas nrog kev ncig mus los tas li; Kuv ib txwm tsis tswj hwm kom noj mov raws sijhawm. Siofor tau zam txim rau kuv rau qhov tsis raug ntawm cov khoom noj khoom haus, tab sis nrog Gliclazide tus lej no tsis mus, nws tau qeeb me ntsis - hypoglycemia nyob ntawd.
Thiab kuv cov khoom noj txom ncauj txheem tsis txaus. Nws tau mus rau lub ntsiab lus tias thaum lub log koj yuav tsum zom ib lub luav qab zib.
Rov ntsuam xyuas los ntawm Ivan, hnub nyoog 44 xyoo. Tsis ntev los no, hloov chaw ntawm Diabeton, lawv pib muab Gliclazide MV. Thaum xub thawj kuv xav yuav lub tshuaj qub, tab sis tom qab ntawd kuv nyeem cov kev txheeb xyuas thiab txiav txim siab sim tshuaj tshiab. Kuv tsis hnov qhov txawv, tab sis 600 rubles. txais kev cawmdim. Ob leeg tshuaj txo cov suab thaj kom zoo thiab txhim kho kuv lub dag zog. Kev mob ntshav qab zib tsawg tsawg thiab kuv qhov kev txhaum ua tas li. Thaum tsaus ntuj, qab zib tsis poob, tshwj xeeb yog kuaj xyuas.
Tso cov ntaub ntawv thiab cov nyob ua ke
Cov tshuaj muaj nyob rau hauv daim ntawv ntawm cov tshuaj, uas yog tus cwj pwm los ntawm kev tso tawm ntev. Cov neeg tsim khoom lag luam muab 2 koob tshuaj: 30 mg thiab 60 mg. Cov ntsiav tshuaj muaj ib puag ncig biconvex duab thiab dawb xim. Cov tshuaj muaj pes tsawg leeg suav nrog:
- cov tshuaj nquag (gliclazide),
- cov khoom sib xyaw ntxiv: colloidal silicon dioxide, cellulose microcrystals, magnesium stearate (E572), hydroxypropyl methylcellulose, mannitol, hydrogenated zaub roj.
Cov tshuaj muaj nyob rau hauv daim ntawv ntawm cov tshuaj, uas yog tus cwj pwm los ntawm kev tso tawm ntev.
Nrog saib xyuas
Cov tshuaj tuaj yeem siv rau kev ua haujlwm me me mus rau lub raum thiab mob siab ua haujlwm. Cov tshuaj yog tshuaj nrog ceev faj nyob rau hauv lub hauv qab no pathologies thiab tej yam kev mob:
- ntsuas tsis tau lossis noj tsis tau
- cov kab mob endocrine
- mob hnyav ntawm CVS,
- piam thaj-6-phosphate dehydrogenase tsis txaus,
- quav cawv
- cov neeg laus laus (65 xyoo thiab laus dua).
Kev kho thiab tiv thaiv mob ntshav qab zib
Thawj qhov tshuaj tiv thaiv thawj zaug hauv kev kho mob ntawm qhov tsis yog-insulin-mob ntshav qab zib thiab kev siv sulfonylurea yuav tsum tsis pub tshaj 75-80 g. Rau kev tiv thaiv, cov tshuaj siv ntawm 30-60 mg / hnub.
Hauv qhov no, tus kws kho mob yuav tsum ua tib zoo saib xyuas qib hauv qab zib hauv tus neeg mob 2 teev tom qab noj mov thiab hauv lub plab khoob.
Yog tias nws pom tias qhov tshuaj no tsis ua haujlwm zoo, ces nws nce ntau hnub ntxiv.
Cov tshuaj muaj qhov ua tau zoo rau lub cev. Txawm li cas los xij, nrog kev siv tshuaj ntev, cov neeg mob yuav muaj kev phiv tshuaj.
Rau kev tiv thaiv lub hom phiaj, cov tshuaj siv tau ntawm 30-60 mg / hnub.
Ntawm ib sab ntawm daim siab thiab cov hnyuv
- kab mob siab
- cholestatic mob daj ntseg.
- poob ntawm kev pom tseeb ntawm kev nkag siab,
- nce siab intraocular.
Cov tshuaj siv nyob rau hauv ua ke nrog nrog ib tug noj tsawg-carb kev noj haus.
Thaum noj nws, tus neeg mob yuav tsum muaj kev tswj hwm kev tswj hwm kev coj ncaj ntawm cov piam thaj hauv cov ntshav.
Thaum noj cov tshuaj, tus neeg mob yuav tsum tswj hwm kev saib xyuas ntawm cov piam thaj hauv cov ntshav.
Hauv cov ntshav qab zib mellitus nyob rau theem decompensation lossis tom qab kev phais mob, kev siv tshuaj insulin npaj yuav tsum tau txiav txim siab.
Kev Tshaj Tawm Gliclazide Canon rau Cov Menyuam
Cov tshuaj tsis pub rau me nyuam yaus siv.
Cov neeg laus muaj cai siv cov tshuaj kho mob tsawg kawg thiab kev saib xyuas mob nkeeg.
Nws yog txwv tsis pub siv cov tshuaj no nrog hypoglycemic effect hauv kev mob plab raum loj. Cov koob tshuaj yog xaiv ib tus zuj zus nyob ntawm seb cov mob ntawm cov neeg mob uas lub raum tsis ua haujlwm.
Tsis pom zoo kev sib txuas ua ke
Nws yog qhov tsis tsim nyog siv cov tshuaj uas muaj ethanol thiab tshuaj uas muaj chlorpromazine ib txhij nrog cov tshuaj hauv cov lus nug.
Phenylbutazone, Danazole thiab cawv ntau ntxiv cov nyhuv hypoglycemic ntawm cov tshuaj. Hauv qhov no, nws zoo dua los xaiv cov tshuaj sib txuam sib txuam.
Tej kev sib txuam uas xav tau ceev faj
Kev sib xyaw ntawm cov tshuaj nrog Acarbose, beta-blockers, biguanides, Insulin, Enalapril, Captopril thiab qee cov tshuaj tiv thaiv tsis-tshuaj steroidal thiab tshuaj muaj chlorpromazine xav tau kev saib xyuas tshwj xeeb, vim hais tias nyob rau hauv cov teeb meem no muaj kev pheej hmoo ntawm hypoglycemia.
Lawj xeeb
Arkady Smirnov, 46 xyoo, Voronezh.
Yog tias tsis yog rau cov tshuaj no, ces kuv txhais tes yuav muaj lub sijhawm ntev dhau los. Kuv tau muaj tus mob ntshav qab zib hom 2 ntev heev. Cov tshuaj no tswj ntshav qab zib kom zoo. Ntawm cov kev mob tshwm sim, Kuv ntsib tsuas yog xeev siab, tab sis nws dhau nws tus kheej tom qab ob peb hnub.
Inga Klimova, 42 xyoos, Lipetsk.
Kuv niam muaj cov ntshav qab zib uas tsis txuas rau insulin. Tus kws kho mob sau cov tshuaj rau nws. Tam sim no nws tau zoo siab thiab qab dua lub neej.