Fabkis-tsim insulin Humalog thiab cov yam ntxwv ntawm nws txoj kev tswj hwm nrog tus cwj mem syringe

Cov tshuaj Insulin Humalog yog DNA hloov kho cov qauv ntawm cov tshuaj insulin. Cov yam ntxwv tshwj xeeb yog kev hloov pauv ntawm kev sib xyaw ntawm cov amino acids nyob rau hauv insulin B saw.

Cov tshuaj tswj cov txheej txheem piam thaj metabolism thiab muaj anabolic sivCov. Thaum qhia rau hauv tib neeg cov leeg nqaij, cov ntsiab lus nce ntxiv glycerol, glycogenfatty acids uas yog txhim khoprotein ua kom sib haum, kev noj ntawm cov amino acids yog nce ntxiv, txawm li cas los xij, thaum lub sij hawm zuj zus gluconeogenesis, ketogenesis, glycogenolysis, lipolysistso tawm amino acidsthiab catabolism muaj protein ntau.

Yog tias muaj mob ntshav qab zib mellitus 1thiab2hom ntawmnrog rau kev qhia ntawm cov tshuaj tom qab noj mov, muaj lus tshaj tawm hyperglycemiahais txog kev nqis tes ntawm tib neeg insulin. Lub sijhawm ntawm Lizpro nws txawv thiab nyob ntawm ntau yam - koob tshuaj, ntsuas kub ntawm lub cev, txhaj tshuaj qhov chaw, ntshav qhov ntshav, ua haujlwm ntawm lub cev.

Lizpro insulin cov thawj coj yog nrog los ntawm kev txo qis hauv cov ntu nocturnal hypoglycemia hauv cov neeg mob ntshav qab zib mellitus, thiab nws txoj kev ua piv nrog tib neeg cov tshuaj insulin tshwm sim sai dua (nruab nrab tom qab 15 feeb) thiab kav ntev dua (txij li 2 txog 5 teev).

Cov ntawv qhia ua lus, cov lus qhia rau kev siv

Cov koob tshuaj ntawm cov tshuaj tau teeb tsa ua ib tus zuj zus nyob ntawm qhov rhiab ntawm cov neeg mob mus rau tshuaj exogenous thiab lawv mob. Nws raug nquahu kom tswj cov tshuaj tsis pub dhau 15 feeb ua ntej lossis tom qab noj mov. Cov txheej txheem kev tswj hwm yog tus kheej. Ua li ntawd, tshuaj kub yuav tsum tau nyob theem theem.

Kev ua txhua hnub tuaj yeem sib txawv, muaj ntau qhov ntau rau 0.5-1 IU / kg. Nyob rau yav tom ntej, cov koob tshuaj txhua hnub thiab ib zaug ntawm cov tshuaj tau raug hloov kho nyob ntawm tus neeg mob metabolism thiab cov ntaub ntawv los ntawm ntau cov ntshav thiab cov zis ntsuas cov ntshav qabzib.

Kev tswj hwm kev siv tshuaj ntawm Humalog yog nqa tawm raws li kev txhaj tshuaj rau cov tshuaj tua kabmob. Kev txhaj tshuaj subcutaneous yog tsim nyob rau hauv lub xub pwg, pob tw, ncej puab lossis hauv plab, ntu hloov lawv thiab tsis pub siv qhov chaw ntau tshaj ib hlis ib zaug, thiab qhov chaw txhaj tshuaj yuav tsum tsis txhob muab zaws. Thaum ua cov txheej txheem, yuav tsum tau saib xyuas kom tsis txhob nkag rau hauv cov hlab ntshav.

Tus neeg mob yuav tsum tau kawm cov txheej txheem txhaj tshuaj kom raug.

Noj ntau dhau

Kev noj tshuaj ntau dhau hwv tuaj yeem ua rau ntshav qognrog los lus muaj mob nkees, tawm hws, ntuav, apathytshee hnyo, tsis hnov ​​mob, tachycardiamob taub hau. Nyob rau tib lub sijhawm, hypoglycemia tuaj yeem tshwm sim tsis yog hauv kev siv tshuaj ntau dhau, tab sis kuj yog qhov tshwm sim kev siv tshuaj insulin ntau ntxivtshwm sim los ntawm lub zog siv los noj. Ua raws li qhov mob hnyav ntawm lub qog ntshav qab zib, cov kev ntsuas tsim nyog yuav tau ua.

Kev sib txuam

Cov nyhuv hypoglycemic ntawm cov tshuaj yog txo, cov tshuaj cov thyroid hormones, GKS, beta 2-adrenergic agonists, tricyclic cov tshuaj tiv thaiv kev ntxhov siab, tshuaj kho mob, Diazoxide,,, derivatives phenothiazine, nicotinic acid.

Kev txo lub plawv tsis zoo ntawm cov tshuaj yog kho kom zoo anabolic tshuaj yuam, beta blockerstshuaj ethanol-muaj cov tshuaj Fenfluramine, tetracyclines, Guanethidine, MAO inhibitors, tshuaj tiv thaiv qhov ncauj hypoglycemic, salicylates, sulfonamides, ACE inhibitors, .

Humalog nyob rau hauv ib tug xwj syringe: nta

Tib neeg yog yam hloov kho DNA ntawm tib neeg cov kua dej. Nws lub ntsiab tseem ceeb yog qhov hloov pauv ntawm kev sib xyaw ntawm cov amino acids nyob rau hauv cov yeeb yaj kiab insulin. Cov tshuaj tswj cov metabolism hauv qabzib. Nws muaj cov nyhuv anabolic.

Khoom Siv Humulin Insulin Cartridges

Nrog rau kev qhia ntawm Humalog, qhov kev ntxig ntawm glycogen, glycerol, cov roj ntsha rog nce ntxiv. Protein synthesis kuj tseem txhim kho. Kev noj ntawm cov amino acids ntau dua. Tib lub sijhawm, ketogenesis, gluconeogenesis, lipolysis, glycogenolysis, protein catabolism thiab kev tso tawm ntawm cov amino acids kuj raug txo. Tib neeg yog insulin-luv ua yeeb yam.

Yam khoom muaj sia


Lub ntsiab nquag tivthaiv ntawm Humalog yog insulin lispro.

Ib lub thawv muaj 100 IU.

Ntxiv rau, muaj cov pabcuam: glycerol, zinc oxide, sodium hydroxide 10% kev daws, hydrochloric acid 10% tov, sodium hydrogen phosphate heptahydrate, metacresol, dej rau kev txhaj tshuaj.

Cov tshuaj Insulin Humalog sib xyaw: 25, 50, 100

Ntshav qab zib yog ntshai ntawm cov tshuaj no, zoo li hluav taws!

Koj tsuas yog xav tau thov ...

Humalog sib tov 25, 50 thiab 100 sib txawv ntawm qhov Humalog li ib txwm los ntawm qhov pom ntawm ib qho khoom ntxiv - cov tshuaj nruab nrab tiv thaiv Hagedorn (NPH).

Lub ntsiab no pab kom qeeb qeeb ntawm kev ua haujlwm ntawm insulin.

Hauv cov tshuaj sib xyaw, qhov muaj nuj nqis ntawm 25, 50 thiab 100 qhia txog kev saib xyuas ntawm NPH. Qhov ntau ntawm cov khoom tivthaiv no, qhov kev ua ntawm ntau dua ntawm kev txhaj tshuaj yog ntev dua. Qhov zoo dua yog tias lawv txo qhov tsawg ntawm cov naj npawb txhua hnub ntawm kev hno.

Qhov no yooj yim kho cov kev kho mob thiab ua rau lub neej ntawm cov neeg mob ntshav qab zib zoo dua nyob. Qhov tsis zoo ntawm qhov sib xyaw ntawm Humalog yog tias nws tsis muab cov ntshav khov khov khov tswj tau. NPH feem ntau provokes kev tsis haum tshuaj, cov tsos ntawm ib tug xov tooj ntawm phiv.

Endocrinologist tsis tshua muaj tshuaj kho ntau ntxiv, vim hais tias kev kho mob ua rau muaj mob ntev thiab mob ntshav qab zib.

Cov tshuaj insulin no tsuas yog tsim rau cov neeg mob ntshav qab zib hauv lub hnub nyoog, uas nws lub neej muaj sia nyob luv luv, senile dementia tau pib. Txog rau lwm pawg ntawm cov neeg mob, cov kws kho mob tau pom zoo kom siv lub tshuab huv huv.

Cov lus qhia rau kev siv


Cov tshuaj Humalog yog qhia rau kev kho mob ntshav qab zib hauv cov neeg laus thiab cov menyuam yaus uas xav tau cov tshuaj insulin txhua hnub kom tswj tau cov ntshav qabzib.

Qhov ntau thiab tsawg zaus ntawm kev siv yog txiav txim los ntawm tus kws kho mob. Cov tshuaj tuaj yeem muab tshuaj intramuscularly, subcutaneously lossis txhaj tshuaj leeg. Txoj kev tom kawg ntawm kev siv yog haum rau cov mob hauv tsev kho mob xwb.

Kev tswj hwm ntawm cov leeg hauv tsev yog cuam tshuam nrog qee qhov kev pheej hmoo. Lub humalogue hauv daim cartridges tau txhaj tshuaj tshwj xeeb subcutaneously siv ib rab koob xaum xim.

Cov tshuaj yuav tsum tau siv 5-15 feeb ua ntej tswj hwm lossis tam sim ntawd tom qab noj mov. Kev txhaj tshuaj yog ua tiav 4-6 zaug hauv ib hnub. Yog hais tias tus neeg mob tau ntxiv qhov kws kho mob ntev zog, ces Humalog yuav txhaj peb zaug ib hnub.

Qhov ntau kawg ntawm cov tshuaj yog teem los ntawm kws kho mob. Tshaj li nws raug tso cai hauv qee kis. Cov tshuaj tau tso cai los ua ke nrog lwm cov kab mob ntawm tib neeg cov tshuaj insulin. Txhawm rau ua qhov no, ntxiv ib qho tshuaj thib ob rau hauv daim cartridge.

Niaj hnub nimno koob tshuaj ntaus pob txig ua rau kev txhaj tshuaj yooj yim dua. Ua ntej siv, daim cartridge yuav tsum tau muab dov hauv cov xib teg. Qhov no yog ua tiav kom cov ntsiab lus dhau los ua cov xim zoo ib yam thiab xwm yeem. Tsis txhob co lub taub hau loj. Txwv tsis pub, ua npuas ncauj yuav tsim, uas yuav cuam tshuam nrog kev qhia ntawm cov nyiaj.

Hauv qab no piav qhia txog lub algorithm rau kev txhaj tshuaj kom raug:

  • ntxuav koj txhais tes kom huv si nrog xab npum,
  • xaiv qhov chaw rau kev txhaj tshuaj thiab so nws nrog cawv,
  • co cov xaum xaum xaum hluav taws xob nrog daim cartridge muab tso rau hauv nws hauv cov lus qhia sib txawv lossis tig dhau 10 zaug. Txoj kev daws teeb meem yuav tsum zoo xws li xim, tsis muaj xim thiab pob tshab. Tsis txhob siv lub thawv ntawv nrog cov huab, me ntsis xim, lossis cov ntawv tuab. Qhov no qhia tau tias cov tshuaj tau ploj zuj zus vim qhov tseeb tau khaws cia tsis raug lossis hnub siv tsis tau dhau caij nyoog,
  • teeb qhov tsuas tshuaj
  • tshem tawm cov kev tiv thaiv ntawm rab koob,
  • txhim kho cov tawv nqaij
  • tag nrho ntxig rau hauv rab koob. Hauv qhov no, koj yuav tsum ceev faj kom tsis txhob nkag mus rau hauv cov hlab ntshav,
  • nias lub khawm ntawm qhov kov thiab tuav nws,
  • Thaum lub suab nrov tso tawm kom tiav qhov kev txhaj tshuaj, tos 10 vib nas this thiab tshem lub koob. Ntawm qhov ntsuas, qhov koob tshuaj yuav tsum yog xoom,
  • tshem cov ntshav uas tshwm tuaj nrog rau ntawd. Koj tsis tuaj yeem zaws lossis txhuam qhov chaw txhaj tshuaj tom qab txhaj,
  • muab lub hau tiv thaiv ntawm tus dais.

Qhov ntsuas kub ntawm cov tshuaj txhaj yuav tsum yog chav kub. Subcutaneously, cov tshuaj raug txhaj rau hauv tus ncej puab, lub xub pwg, lub plab lossis pob tw. Kev teev nqi txhua zaus nyob hauv tib qho chaw yog tsis pom zoo. Cov chaw hauv lub cev yuav tsum sib hloov txhua hli.

Ua ntej siv thiab tom qab cov txheej txheem, tus neeg mob yuav tsum ntsuas ntshav qab zib nrog glucometer. Txwv tsis pub, nws muaj qhov pheej hmoo ntawm lub qog ntshav qab zib.

Humalog muaj qee qhov tsis sib haum:

  • ntshav qab zib,
  • intolerance rau insulin lyspro lossis lwm yam tshuaj.

Thaum siv Humalog, nws yuav tsum tau yug los hauv lub siab tias nyob rau hauv kev cuam tshuam ntawm qee yam tshuaj, xav tau txhaj tshuaj yuav hloov.

Piv txwv, cov tshuaj tiv thaiv qhov ncauj, corticosteroids muaj cov nyhuv hyperglycemic. Yog li, koj yuav tsum tswj hwm cov tshuaj hauv ib qhov ntau dua. Thaum noj cov tshuaj tiv thaiv kab mob hauv lub qhov ncauj, tshuaj tiv thaiv kab mob siab, salicylates, ACE inhibitors, beta-blockers, qhov xav tau rau insulin yog txo qis.

Cov tshuaj Humalog yog tso cai siv thaum siv thaum cev xeeb tubCov. Tsis muaj cov kev mob tshwm sim hauv cov poj niam hauv txoj hauj lwm siv cov kev txhaj tshuaj ntawm cov tshuaj no. Cov khoom lag luam tsis cuam tshuam rau kev noj qab haus huv ntawm tus menyuam los yog tus menyuam tshiab. Tab sis nyob rau lub sijhawm no, koj yuav tsum ua tib zoo saib xyuas cov kua qab zib hauv cov ntshav.


Hauv thawj peb lub hlis, xav tau cov tshuaj insulin feem ntau poob qis, thiab nyob rau lub hlis thib ob thiab peb nce ntxiv. Thaum lub sijhawm lactation, kev hloov kho cov tshuaj insulin kuj tseem xav tau.

Nws tsis muaj kev thaj tsam kev txiav txim siab rau kev siv ntau tshaj. Tom qab tag nrho, cov concentration ntawm cov piam thaj hauv cov ntshav yog qhov tshwm sim ntawm kev sib txuam ntawm cov kua dej, muaj cov piam thaj, thiab cov metabolism.

Yog tias koj nkag mus ntau dhau lawm, hypoglycemia yuav tshwm sim. Hauv qhov no, cov tsos mob hauv qab no tau pom: tsis pom kev, nkees, tawm hws, tsis hnov ​​qab, tachycardia, mob taub hau, ntuav, tshee ntawm lub qhov kawg. Kev noj ntshav qab zib kom tsawg yog feem ntau tshem tawm los ntawm kev noj cov ntsiav tshuaj qabzib, cov khoom muaj suab thaj.

Txhawm rau tiv thaiv hypoglycemia thaum lub sijhawm hloov mus rau Humalog, ib qho yuav tsum tau saib xyuas kev noj qab haus huv. Koj yuav tau yoog koj cov zaub mov noj, qoj ib ce, xaiv tshuaj.

Cov kev tawm tsam hnyav ntawm cov ntshav qog nqaij hlav, uas nrog los ntawm cov leeg mob puas hlwb, tsis nco qab, yuav tsum tau ua tshuaj intramuscular lossis subcutaneous ntawm glucagon. Yog tias tsis muaj qhov tshuaj tiv thaiv rau cov tshuaj yeeb dej caw no, tom qab ntawd cov tshuaj kua qabzib 40% yuav tsum tau txhaj tshuaj nrog lub ntsej muag. Thaum tus neeg mob rov qab nco qab, nws yuav tsum tau noj cov zaub mov carbohydrate, vim tias nws muaj kev pheej hmoo ntawm cov kev rov qab qog ntshav qab zib.

Thaum siv lub Humalog, cov kev mob tshwm sim tuaj yeem tshwm sim:

  • kev tsis haumCov. Lawv raug pom muaj tsawg kawg nkaus, tab sis muaj qhov hnyav heev. Tus neeg mob yuav ua tsis taus pa, khaus thoob plaws lub cev, tawm hws, lub plawv dhia, tso ntshav tawm, ua pa nyuaj. Ib qho mob hnyav txaus ntshai rau lub neej
  • ntshav qogCov. Feem ntau cov kev mob tshwm sim los ntawm kev kho kev kho ntshav qab zib,
  • cov tshuaj tiv thaiv hauv zos (ua pob, liab liab, khaus, lipodystrophy). Dhau tom qab ob peb hnub, lub lim tiam.

Humalog yuav tsum tau muab cia rau hauv qhov chaw qhuav thiab tsaus ntawm qhov kub ntawm +15 txog +25 degrees. Cov tshuaj yuav tsum tsis txhob tso ze ntawm cov pa roj hlawv lossis ntawm lub roj teeb ua ntej siv. Lub cartridge yuav tsum tau tuav hauv xib teg ntawm koj txhais tes.

Muaj ntau qhov kev txheeb xyuas ntawm Humalog nyob rau hauv cov xaum xim. Thiab lawv feem ntau muaj qhov zoo:

  • NatalyaCov. Kuv muaj ntshav qab zib. Kuv siv Humalog hauv qhov xaum qhuav. Zoo nyob heev. Qab zib sai dauv mus rau theem ib txwm muaj. Yav dhau los, nws txhaj Actrapid thiab Protafan. Ntawm Humalog Kuv xav tias zoo dua thiab muaj kev ntseeg siab dua. Kev muaj ntshav qab zib tsis tshwm sim,
  • OlgaCov. Kuv mob ntshav qab zib xyoo ob.Lub sijhawm no kuv sim cov insulins sib txawv. Ntev ntev yeeb tshuaj nqa tam sim. Tab sis nrog kev siv tshuaj yeeb-luv luv rau lub sijhawm ntev kuv tsis tuaj yeem txiav txim siab. Ntawm txhua tus paub, Humalog hauv Cov Tshuaj Tiv Thaiv Ceev ceev tau haum rau kuv. Nws sai thiab zoo txo ​​qis suab thaj. Ua tsaug rau tus kov nws yooj yim siv. Ua ntej cov lus qhia, Kuv suav cov khob cij thiab xaiv cov koob tshuaj. Twb tau ib nrab xyoo ntawm Humalog thiab kom deb li deb Kuv yuav tsis hloov nws,
  • AndreyCov. Xyoo tsib muaj mob ntshav qab zib. Mob tas li nrog quaj nyob rau hauv cov ntshav piam thaj. Tsis ntev los no, Kuv tau pauv mus rau Humalog. Kuv zoo siab tam sim no, cov tshuaj muab nyiaj zoo. Nws tsuas yog drawback yog tus nqi siab,
  • Marina Kuv tau mob ntshav qab zib txij li 10 xyoo. Txog thaum muaj hnub nyoog 12 xyoos, nws coj cov ntsiav tshuaj txo qis qab zib. Tiamsis tom qab ntawd lawv tsum tsis pab kuv lawm. Vim tias qhov no, tus kws kho mob endocrinologist pom zoo hloov mus rau lub zog insulin. Kuv yeej tsis xav tau qhov no thiab tiv thaiv. Tab sis thaum pom kev tsis pom kev zoo, thiab cov teeb meem lub raum tau tshwm sim, Kuv pom zoo. Kuv tsis khuv xim kuv qhov kev txiav txim siab. Ua kev txhaj tshuaj yog tsis txaus ntshai. Qab zib tam sim no tsis tau siab dua 10. Kuv zoo siab nrog cov tshuaj.

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Cov lus qhia rau kev siv tshuaj insulin Humalog hauv video:

Yog li, Humalog nyob hauv rab koob txhaj tshuaj yog qhov zoo tshaj plaws tshuaj rau cov neeg muaj mob ntshav qab zib. Nws muaj ob peb contraindications thiab phiv. Ua tsaug rau cov koob txhaj tshuaj syringe, kev tsim koob tshuaj thiab kev tswj hwm tshuaj yog yooj yim dua. Cov neeg mob muaj lub tswv yim zoo txog hom tshuaj insulin no.

Fab Kis ua insulin humalogue thiab cov yam ntxwv ntawm nws txoj kev tswj hwm siv cwj mem syringe. Cov lus qhia siv xov tooj rau kev siv

Hauv tsab xov xwm no, koj tuaj yeem nyeem cov lus qhia rau kev siv tshuaj yaj yeeb Neej Neeg Cov. Muab cov lus pom zoo los ntawm cov neeg tuaj saib rau ntawm thaj chaw - cov neeg tau txais kev pab ntawm cov tshuaj no, nrog rau kev xav ntawm cov kws kho mob tshwj xeeb txog kev siv Humalog hauv lawv cov kev coj ua. Qhov kev thov loj yog nquag ntxiv kev tshuaj xyuas koj ntawm cov tshuaj: cov tshuaj tau pab lossis tsis pab ua kom tshem tawm ntawm tus kabmob, muaj dab tsi tshwm sim thiab cov kev mob tshwm sim, tejzaum nws tsis tshaj tawm los ntawm tus tsim khoom hauv cov lus piav qhia. Cov Txiaj Ntsig ntawm Humalog nyob rau hauv muaj cov qauv txheej txheem qauv. Siv rau kev kho mob ntawm hom 1 thiab hom 2 mob ntshav qab zib mellitus (ntshav qab zib-insulin thiab tsis-insulin-mob ntshav qab zib) rau cov neeg laus, menyuam, nrog rau lub sijhawm cev xeeb tub thiab lactation. Cov tshuaj muaj pes tsawg leeg.

Neej Neeg - cov duab ntawm cov tshuaj insulin, txawv ntawm nws los ntawm kev rov qab ua ntu zus ntawm cov kab sib luag thiab lysine amino acid seem ntawm txoj haujlwm 28 thiab 29 ntawm cov kab insulin B. Piv nrog luv luv ua yeeb yam npaj cov tshuaj insulin, lyspro insulin yog tus yam ntxwv sai dua ntawm qhov pib thiab qhov kawg ntawm cov nyhuv, uas yog vim muaj kev nqus ntxiv los ntawm subcutaneous depot vim yog kev txuag ntawm monomeric qauv ntawm lyspro insulin lwg me me hauv cov tshuaj. Qhov pib ntawm kev ua yog 15 feeb tom qab tswj hwm subcutaneous, qhov ua haujlwm siab tshaj plaws yog nruab nrab ntawm 0.5 teev thiab 2.5 teev, lub sijhawm ua ntawm 3-4 teev.

Humalog Mix yog DNA - recombinant analogue ntawm tib neeg cov kua dej thiab yog qhov sib xyaw ua ke uas muaj lyspro insulin tov (kev ua kom sai ntawm tib neeg cov tshuaj insulin) thiab kev ncua ntawm lyspro protamine insulin (nruab nrab ntev tib neeg cov tshuaj insulin).

Kev ua tseem ceeb ntawm insulin lyspro yog txoj cai ntawm cov metabolism hauv qabzib. Tsis tas li ntawd, nws muaj anabolic thiab anti-catabolic cuam tshuam rau ntau cov ntaub so ntswg lub cev. Hauv cov leeg nqaij, muaj qhov nce ntawm cov ntsiab lus ntawm glycogen, fatty acids, glycerol, kev nce ntawm synthesis protein thiab nce ntxiv ntawm kev noj cov amino acids, tab sis tib lub sijhawm muaj glycogenolysis, gluconeogenesis, ketogenesis, lipolysis, protein catabolism thiab kev tso tawm ntawm cov amino acids.

Lyspro insulin + excipients.

Kev ua tiav ntawm kev nqus thiab pib ntawm cov nyhuv ntawm cov tshuaj insulin nyob ntawm qhov chaw txhaj tshuaj (plab, ncej, pob tw), qhov koob tshuaj (ntim ntawm txhaj tshuaj insulin), thiab qhov tob ntawm cov tshuaj insulin hauv kev npaj. Nws tau faib tawm tsis ncaj hauv daim ntaub. Nws tsis hla tus cwj pwm ntawm lub tso mis thiab nkag rau hauv niam mis. Nws yog rhuav tshem los ntawm insulinase feem ntau hauv daim siab thiab lub raum. Nws yog tawm los ntawm lub raum - 30-80%.

  • yam 1 mob ntshav qab zib mellitus (insulin-dependant), suav nrog nrog kev tsis nkag siab rau lwm txoj kev npaj tshuaj insulin, nrog postprandial hyperglycemia uas tsis tuaj yeem kho los ntawm lwm yam kev npaj tshuaj insulin, mob subcutaneous insulin tsis kam (nrawm hauv lub zos insulin degradation),
  • yam 2 mob ntshav qab zib mellitus (non-insulin-dependant): nrog kev tawm tsam cov tshuaj tiv thaiv kab mob hauv lub qhov ncauj, nrog rau kev nqus tsis tau ntawm lwm yam tshuaj insulin, kev tiv thaiv tsis tau zoo tom qab hyperglycemia, thaum lub sijhawm ua haujlwm, cov kabmob sib kis.

Ib qho kev daws teeb meem rau kev tswj hwm kom haum thiab subcutaneous ntawm 100 IU hauv 3 ml cartridge sib xyaw rau hauv QuickPen cwj mem los yog cwj mem kua txho.

Ncua rau kev rho tawm ntawm 100 IU hauv 3 ml cartridge sib xyaw rau hauv QuickPen cwj mem los yog cwj mem kua (Humalog Mix 25 thiab 50).

Lwm cov ntaub ntawv ntau npaum li cas, tsis pub muaj ntsiav tshuaj lossis tsiav tshuaj, tsis muaj nyob.

Cov lus qhia rau kev siv thiab qauv ntawm kev siv

Qhov ntau npaum li cas tau teev cia ua ib tus zuj zus. Lyspro insulin yog muab tshuaj subcutaneously, intramuscularly lossis intravenously 5-15 feeb ua ntej noj mov. Ib koob tshuaj yog 40 units, ntau dhau tsuas tso cai tshwj xeeb. Nrog rau cov tshuaj tua kab mob, Lyspro insulin muab rau 4-6 zaug hauv ib hnub, ua ke nrog kev npaj tshuaj insulin ntev - 3 zaug hauv ib hnub.

Cov tshuaj yuav tsum tau muab tshuaj subcutaneously.

Tso dej siab tswj hwm ntawm cov tshuaj Humalog Mix yog contraindicated.

Qhov ntsuas kub ntawm cov tshuaj tso cai yuav tsum nyob ntawm chav sov.

Subcutaneously yuav tsum nkag mus rau hauv lub xub pwg, ncej puab, pob tw los yog lub plab. Qhov chaw txhaj tshuaj yuav tsum tau hloov chaw kom tib qhov chaw siv tsis ntau tshaj 1 zaug hauv ib hlis. Thaum s / qhia txog cov tshuaj Humalog, kev saib xyuas yuav tsum tau saib xyuas kom tsis txhob txais cov tshuaj rau hauv cov hlab ntsha. Tom qab txhaj tshuaj, qhov chaw txhaj tshuaj yuav tsum tsis txhob zaws.

Thaum txhim kho lub taub hau hauv lub twj txhaj tshuaj insulin thiab txuas lub koob ua ntej insulin thawj coj, cov lus qhia ntawm cov chaw tsim khoom ntawm cov cuab yeej siv tshuaj insulin yuav tsum ua raws cai.

Cov kev cai rau kev qhia ntawm cov tshuaj Humalog Mix

Npaj rau kev qhia

Tam sim ntawd ua ntej siv, Humalog Mix sib xyaw cartridge yuav tsum tau muab sib dhos ntawm xib teg kaum npaug thiab tshee, tig ntawm 180 ° kuj kaum zaus kom rov kho cov tshuaj insulin kom txog thaum nws zoo li homogeneous huab lossis kua mis. Tsis txhob co khov kho, raws li qhov no tuaj yeem ua rau npuas dej, uas tuaj yeem cuam tshuam nrog cov koob tshuaj kom raug. Txhawm rau kom yooj yim rau kev sib xyaw, lub pob txha taub ntawv muaj lub khob iav me me. Cov tshuaj yuav tsum tsis txhob siv yog tias nws muaj plaub yaig tom qab tov.

Yuav siv cov tshuaj li cas

  1. Ntxuav tes.
  2. Xaiv ib qho chaw rau kev txhaj tshuaj.
  3. Kho cov tawv nqaij nrog tshuaj tua kab mob ntawm qhov chaw txhaj tshuaj (nrog rau kev coj tus kheej, raws li tus kws kho mob cov lus pom zoo).
  4. Tshem lub hau tiv thaiv sab nraud ntawm rab koob.
  5. Txhim kho cov tawv nqaij los ntawm rub nws los yog khi cov quav loj.
  6. Ntxig lub koob txhaj tshuaj subcutaneously thiab ua qhov kev txhaj tshuaj raws li cov lus qhia siv kev siv tus xaum xim.
  7. Tshem tawm rab koob thiab maj mam muab nyem qhov chaw txhaj tshuaj rau ob peb feeb. Tsis txhob txhuam thaj chaw txhaj tshuaj.
  8. Siv lub hau sab tiv thaiv ntawm rab koob, unscrew lub koob thiab rhuav tshem nws.
  9. Tso lub hau rau ntawm tus cwj mem xaum qhuav.

  • hypoglycemia (mob ntshav qab zib heev tuaj yeem ua rau tsis nco qab thiab, tshwj tsis yog mob tuag taus),
  • liab, o, lossis khaus ntawm qhov chaw txhaj tshuaj (feem ntau ploj hauv ob peb hnub lossis lim tiam, qee qhov xwm txheej no tuaj yeem yog vim los ntawm tsis muaj feem cuam tshuam nrog insulin, piv txwv li, voos tawv nqaij los ntawm kev siv tshuaj tua kab mob los yog kev txhaj tshuaj tsis zoo),
  • dav khaus
  • ua pa nyuaj
  • txog siav
  • txo hauv cov ntshav siab,
  • tachycardia
  • nce hws
  • kev txhim kho ntawm lipodystrophy ntawm thaj chaw txhaj tshuaj.

  • ntshav qab zib,
  • ua kom lub cev tsis haum rau cov tshuaj ntawm cov tshuaj.

Cev xeeb tub thiab lactation

Txog hnub, tsis muaj qhov xav tau ntawm Lyspro insulin ntawm cev xeeb tub lossis qhov xwm txheej ntawm tus menyuam hauv plab thiab cov menyuam tshiab tau pom.

Lub hom phiaj ntawm kev kho tshuaj insulin thaum cev xeeb tub yog kom tswj tau cov piam thaj kom txaus. Qhov kev xav tau rau insulin feem ntau poob qis hauv thawj peb lub hlis thiab nce hauv qib thib ob thiab thib peb thaum cev xeeb tub. Thaum lub sijhawm thiab yug tom qab yug, insulin yuav tsum poob ntau.

Cov poj niam ntawm lub hnub nyoog yug menyuam uas muaj ntshav qab zib yuav tsum qhia tus kws kho mob txog qhov pib lossis npaj yuav xeeb tub.

Hauv cov neeg mob uas mob ntshav qab zib mellitus thaum pub niam mis, yuav tsum tau txhaj tshuaj insulin thiab / lossis noj zaub mov kom haum.

Cov kab ke ntawm cov thawj coj npaj rau kev siv ntau npaum ntawm lyspro insulin yuav tsum nruj me ntsis. Thaum hloov mus rau cov neeg mob los ntawm kev ua yeeb yam sai sai insulin npaj cov tsiaj keeb kwm rau insulin lispro, yuav tsum tau txhaj koob tshuaj. Kev hloov chaw ntawm cov neeg mob tau txais cov tshuaj insulin nyob rau hauv ib hnub ntau dua 100 units los ntawm ib hom tshuaj insulin mus rau lwm qhov tau pom zoo kom nqa tawm hauv tsev kho mob.

Kev xav tau rau cov tshuaj insulin tuaj yeem nce ntxiv thaum kis kab mob, nrog kev ntxhov siab hauv lub siab, nrog qhov nce ntawm cov khoom noj carbohydrates hauv cov zaub mov, thaum ntxiv kev noj tshuaj ntxiv nrog hyperglycemic kev ua si (cov thyroid hormones, glucocorticoids, qhov ncauj tiv thaiv, thiazide diuretics).

Qhov xav tau ntawm cov tshuaj insulin yuav txo qis nrog lub raum thiab / lossis lub siab ua haujlwm, nrog qhov kev txiav txim siab ntawm cov khoom noj carbohydrates hauv zaub mov, nrog kev tawm dag zog lub cev, thaum ntxiv kev noj tshuaj nrog hypoglycemic kev ua si (MAO inhibitors, tsis xaiv-beta-blockers, sulfonamides).

Kev kho cov ntshav qog ntshav qab zib hauv qhov mob hnyav tuaj yeem nqa tawm los ntawm kev siv i / m thiab / lossis s / c tswj hwm ntawm glucagon lossis iv kev tswj xyuas ntshav qabzib.

Cov nyhuv hypoglycemic ntawm Lyspro insulin yog txhim kho los ntawm MAO inhibitors, tsis xaiv-beta-blockers, sulfonamides, acarbose, ethanol (cawv) thiab tshuaj uas muaj ethanol.

Cov nyhuv hypoglycemic ntawm Lyspro insulin yog txo los ntawm glucocorticosteroids (GCS), cov thyroid hormones, tshuaj tiv thaiv qhov ncauj, thiazide diuretics, diazoxide, tricyclic antidepressants.

Beta-blockers, clonidine, reserpine tuaj yeem npog qhov tsos ntawm cov tsos mob ntawm qog ntshav qab zib.

Cov tshuaj ntawm cov tshuaj Humalog

Cov qauv ntawm cov qauv ua haujlwm:

  • Lyspro insulin
  • Humalog Mix 25,
  • Neej Neeg Qhia 50.

Cov cim qhia hauv pawg pharmacological (insulins):

  • Tus kws kho mob HM Penfill,
  • Actrapid MS,
  • B-Insulin S.Ts. Berlin Chemie,
  • Berlinsulin H 30/70 U-40,
  • Berlinsulin H 30/70 cwj mem,
  • Berlinsulin N Basal U-40,
  • Berlinsulin N Basal Cwj mem,
  • Berlinsulin Hom U-40,
  • Berlinsulin N Tus Cwj Pwm Zoo Li Cas,
  • Qov tshuaj insulin C,
  • Isofan Insulin Ntiaj Teb Khob,
  • Iletin
  • Insulin Daim Kab Xev SPP,
  • Insulin c
  • Nqaij npuas ua kua txig ntau dhau los ua tiav MK,
  • Insuman Zuag,
  • Rau Sab Kev SPP,
  • Intral Ntiaj Teb Khob,
  • Combinsulin C
  • Mikstard 30 NM Penfill,
  • Monosuinsulin MK,
  • Monotard
  • Pensulin,
  • Protafan HM Penfill,
  • Protafan MS,
  • Rinsulin
  • Ultratard NM,
  • Homolong 40,
  • Hom 40,
  • Neeg lim hiam.

Thaum tsis muaj cov tshuaj analogues rau cov tshuaj rau cov tshuaj yeeb dej caw, koj tuaj yeem nyem rau ntawm qhov txuas hauv qab no rau cov kab mob uas cov tshuaj tsim nyog pab los ntawm thiab pom muaj cov analogues rau kev kho mob nyhuv.

Lub teb chaws Fabkis zoo tshuaj insulin Humalog tau ua pov thawj nws zoo tshaj li analogues, uas yog ua tiav vim muaj kev sib txuam zoo ntawm cov kev ua haujlwm tseem ceeb thiab cov khoom pab txhawb nqa. Kev siv cov tshuaj insulin no ua kom yooj yim rau kev sib ntaus los tiv thaiv hyperglycemia hauv cov neeg mob kev mob ntshav qab zib.

Fab Kis ua insulin humalogue thiab cov yam ntxwv ntawm nws txoj kev tswj hwm siv cwj mem syringe. Cov ntaub ntawv dav dav ntawm kev siv tus cwj mem kom nyab xeeb thiab siv tau. Lub npe thiab chaw nyob ntawm cov chaw tsim khoom

Hauv xaim hluav taws xob.Cov lus qhia rau kev siv cov cuab yeej no tau muab rau hauv kab lus.

Tib neeg yog yam hloov kho DNA ntawm tib neeg cov kua dej. Nws lub ntsiab tseem ceeb yog qhov hloov pauv ntawm kev sib xyaw ntawm cov amino acids nyob rau hauv cov yeeb yaj kiab insulin. Cov tshuaj tswj cov metabolism hauv qabzib. Nws muaj cov nyhuv anabolic.

Khoom Siv Humulin Insulin Cartridges

Nrog rau kev qhia ntawm Humalog, qhov kev ntxig ntawm glycogen, glycerol, cov roj ntsha rog nce ntxiv. Protein synthesis kuj tseem txhim kho. Kev noj ntawm cov amino acids ntau dua. Tib lub sijhawm, ketogenesis, gluconeogenesis, lipolysis, glycogenolysis, protein catabolism thiab kev tso tawm ntawm cov amino acids kuj raug txo. Tib neeg yog insulin-luv ua yeeb yam.

Txoj kev ntawm daim ntawv thov

Cov kev cai rau kev tswj hwm ntawm cov tshuaj Humalog

Npaj rau kev qhia

Kev daws ntawm cov tshuaj Humalog yuav tsum yog pob tshab thiab xim tsis muaj xim. Ib qho huab, tuab lossis xim me ntsis ntawm cov tshuaj, lossis yog tias cov khoom tawg tau pom los rau hauv nws, yuav tsum tsis txhob siv.

Thaum txhim kho lub taub ntim hauv cov koob txhaj tshuaj (tus cwj mem-txhaj), txuas lub koob thiab coj kev txhaj tshuaj insulin, nws yog qhov yuav tsum tau ua raws li cov khw muag cov lus qhia uas txuas nrog txhua tus xaum xim.

Ntxuav tes.
Xaiv ib qho chaw rau kev txhaj tshuaj.
Kho cov tawv nqaij nrog tshuaj tua kab mob ntawm qhov chaw txhaj tshuaj.
Tshem tawm lub hau ntawm rab koob.
Txhim kho cov tawv nqaij los ntawm rub nws los yog khi cov quav loj. Ntxig lub koob txhaj tshuaj raws li cov lus qhia siv kev xaum xim.
Nias lub khawm.
Tshem tawm rab koob thiab maj mam muab nyem qhov chaw txhaj tshuaj rau ob peb feeb. Tsis txhob txhuam thaj chaw txhaj tshuaj.
Siv rab koob rab koob, khi cov koob thiab rhuav nws.
Qhov chaw txhaj tshuaj yuav tsum tau hloov chaw kom tib qhov chaw siv tsis ntau tshaj li 1 zaug hauv ib hlis.
Tso dej insulin
Kev txhaj tshuaj tiv thaiv ntawm Humalog yuav tsum tau nqa tawm raws li kev kuaj mob niaj zaus ntawm kev tso tshuaj txhaj, piv txwv li, cov tshuaj ua haujlwm ntawm cov ntshav khov lossis siv ib txoj kev lis ntshav. Hauv qhov no, nws yog ib qho tsim nyog feem ntau los tswj cov qib ntawm cov piam thaj hauv cov ntshav.
Lub tshuab ua ke nrog cov ntsiab lus los ntawm 0.1 IU / ml rau 1.0 IU / ml ntawm insulin lispro hauv 0.9% sodium chloride tov lossis 5% dextrose daws yog ruaj khov nyob rau chav sov li 48 teev.
Subcutaneous insulin Txoj Kev lis ntshav nrog lub tshuab nqus dej insulin
Rau kev ua txhaum ntawm cov tshuaj Humalog, Minimed thiab Disetronic cov twj tso kua mis tuaj yeem siv rau cov tshuaj insulin. Koj yuav tsum nruj me ntsis ua raws cov lus qhia uas tuaj nrog lub twj tso kua mis. Txoj kev lis ntshav lub cev yog hloov pauv txhua 48 teev. Thaum txuas lub system rau Txoj kev lis ntshav, saib xyuas txoj cai aseptic. Thaum muaj qhov qog ntawm hypoglycemic, Txoj kev lis ntshav yog nres kom txog rau thaum rov zoo. Yog tias pheej rov qab ua lossis txo qis dua cov piam thaj hauv cov ntshav, tom qab ntawd koj yuav tsum qhia koj tus kws kho mob txog qhov no thiab txiav txim siab yuav txo qis lossis tso tseg cov tshuaj insulin. Lub twj tso kua mis tsis ua hauj lwm lossis kev txhaws hauv txoj kev lis ntshav tuaj yeem ua rau nce ntxiv hauv cov piam thaj. Yog tias lub sijhawm ua txhaum cai ntawm kev ua txhaum ntawm kev muab cov tshuaj insulin, koj yuav tsum ua raws li cov lus qhia thiab yog tias tsim nyog, qhia rau tus kws kho mob. Thaum siv lub twj tso kua mis, cov tshuaj Humalog yuav tsum tsis txhob muab sib xyaw nrog lwm cov tshuaj insulins.

Cov Yuav Tsum Tau Ua

Cev xeeb tub thiab lactation
Txog rau hnub no, tsis muaj qhov xav tau ntawm Lyspro insulin rau kev xeeb tub lossis kev noj qab haus huv ntawm tus menyuam / tus menyuam tshiab tau pom. Tsis muaj cov kev tshawb fawb nthuav txog kab mob sib kis.
Lub hom phiaj ntawm insulin txoj kev kho mob thaum cev xeeb tub yog tswj hwm cov ntshav qabzib kom txaus rau cov neeg mob ntshav qab zib insulin-los yog mob ntshav qab zib hauv lub ntsej muag. Qhov xav tau rau insulin feem ntau poob qis hauv thawj peb lub hlis thiab nce hauv qib thib ob thiab thib peb thaum cev xeeb tub. Thaum lub sijhawm thiab yug tom qab yug, insulin yuav tsum poob ntau.
Cov poj niam ntawm lub hnub nyoog yug menyuam uas muaj ntshav qab zib yuav tsum qhia tus kws kho mob txog qhov pib lossis npaj yuav xeeb tub. Thaum cev xeeb tub, cov neeg mob ntshav qab zib yuav tsum ua tib zoo saib xyuas cov ntshav qabzib, nrog rau kev saib xyuas neeg mob txhua yam.
Hauv cov neeg mob uas mob ntshav qab zib mellitus thaum pub niam mis, yuav tsum tau txhaj tshuaj insulin thiab / lossis noj zaub mov kom haum.

Cov lus qhia tshwj xeeb

Mob ntshav qab zib insulin-tiv thaiv mob ntshav qab zib yog ib yam kabmob uas paub tias yuav tsum muaj kev tswj kav insulin tas lub neej. Cov tshuaj insulin yog cov txhaj tshuaj.

Txog rau hnub tim, cov tuam txhab pharmacological ua ntau yam tshuaj insulin rau cov neeg mob ntshav qab zib, npaj rau kev txhaj tshuaj. Cov tshuaj sib txawv no tuaj yeem muaj npe txawv, zoo thiab nqi. Ib qho ntawm lawv yog cov tshuaj Humulin.

Cov Tshuaj Pharmacokinetics

Nrog kev txhaj tshuaj subcutaneous, qhov nqus ntawm lyspro insulin tshwm sim sai sai, nws Cmax tiav tom qab 1-2 teev. Vd ntawm cov kua dej nyob rau hauv kev sib xyaw ntawm cov tshuaj thiab cov tib neeg insulin zoo ib yam, lawv thaj tsam li ntawm 0.26 txog 0.36 litres ib kg.

Daim ntawv tiv thaiv ntshav qab zib: hom mob ntshav qab zib tsis haum rau lwm yam tshuaj insulin, postprandial hyperglycemia, uas tsis tuaj yeem kho los ntawm lwm cov tshuaj insulin.

Daim ntawv uas tsis muaj tshuaj insulin-tiv thaiv cov ntshav qab zib: kev tawm tsam cov tshuaj tiv thaiv ntshav qab zib noj ntawm qhov ncauj (malabsorption ntawm lwm yam tshuaj insulin, kev kho mob tom qab uas tsis tuaj yeem kho), phais kev cuam tshuam thiab mob intercurrent (uas ua rau muaj kev mob ntshav qab zib).

Thov

Dosage Humalog yog txiav txim siab ib tus zuj zus. Humalog nyob rau hauv daim ntawv ntawm vials yog muab ob qho tib si subcutaneously thiab intravenously thiab intramuscularly. Lub humalogue nyob rau hauv daim ntawv ntawm cartridges tsuas yog subcutaneous. Kev txhaj tshuaj yog nqa tawm 1-15 feeb ua ntej noj mov.

Hauv nws daim ntawv dawb huv, cov tshuaj tau muab 4-6 zaug hauv ib hnub, ua ke nrog cov tshuaj insulin nrog cov nyhuv ntev, peb zaug ib hnub. Qhov luaj li cas ntawm ib koob tsis tuaj yeem dhau 40 units. Humalog hauv vials tuaj yeem sib xyaw nrog cov tshuaj insulin nrog cov nyhuv ntev dua hauv ib qho koob txhaj.

Lub pob txha taub hau tsis tsim rau tov Humalog nrog rau lwm yam tshuaj insulin npaj rau hauv nws thiab rau kev rov siv dua.

Qhov xav tau rau txo qis ntawm cov tshuaj insulin tuaj yeem tshwm sim thaum muaj kev cuam tshuam ntawm cov ntsiab lus ntawm cov khoom noj carbohydrates hauv cov khoom noj, qhov kev nyuaj siab ntawm lub cev, kev noj ntxiv ntawm cov tshuaj uas muaj cov nyhuv hypoglycemic - sulfonamides, tsis xaiv cov beta-blockers.

Thaum noj clonidine, beta-blockers thiab reserpine, hypoglycemic cov tsos mob feem ntau tshwm sim.

Sab sij huam

Cov nyhuv tseem ceeb ntawm cov tshuaj no ua rau cov kev mob tshwm sim hauv qab no: nce tawm hws, pw tsis tsaug zog, tsis xeev plab. Tsis tshua muaj xwm txheej, kev ua xua thiab lipodystrophy tuaj yeem tshwm sim.

Txog tam sim no, tsis muaj qhov tsis zoo tshwm sim ntawm Humalog rau kev mob ntawm tus poj niam cev xeeb tub thiab tus mob embryo tau pom. Tsis muaj kev tshawb fawb cuam tshuam tau tshwm sim.

Tus pojniam uas muaj hnub nyoog yug menyuam uas muaj ntshav qab zib yuav tsum qhia tus kws kho mob txog qhov tau npaj lossis yuav xeeb menyuam. Rau cov neeg mob ntshav qab zib, lactation qee zaum yuav tsum tau yoog cov tshuaj insulin lossis kev noj haus.

Kev sib txuam ntawm Pharmacological

Cov nyhuv hauv lub ntsej muag hypoglycemic yog txo qis thaum noj qhov ncauj noj, tshuaj raws li cov thyroid hormones, beta2-adrenergic agonists, danazole, tricyclic antidepressants, thiazide-type diuretics, diazoxide, chlorprotixen, isoniazid, nicotinic acid, lithium carbonate, lithium carbonate.

Cov nyhuv hypoglycemic ntawm Humalog nce nrog beta-blockers, ethyl cawv thiab tshuaj uas muaj nws, fenfluramine, anabolic steroids, tetracyclines, guanethine, salicylates, tshuaj tiv thaiv hypoglycemic, sulfonamides, ACE inhibitors thiab MAO thiab octre.

Cov tshuaj yuav tsum tsis txhob sib xyaw nrog lwm cov khoom uas muaj cov tshuaj insulin ntawm cov tsiaj keeb kwm.

Siv tshuaj Humalog yuav siv tau (raug tshuaj saib xyuas mob) hauv kev sib xyaw nrog tib neeg cov tshuaj insulin, uas muaj cov nyhuv ntev dua, lossis siv nrog cov tshuaj hypoglycemic noj ntawm qhov ncauj, uas yog derivatives ntawm sulfonylurea.

Cov lus qhia rau kev siv

Tso tawm daim ntawv thiab muaj pes tsawg leeg

Dosage form - raug tshem tawm rau kev tswj hwm subcutaneous: cov xim dawb, exfoliating nrog tsim ntawm nag lossis daus thiab pob tshab, yuav luag tsis muaj xim lossis xim tsis muaj xim tshaj plaws, tau nrawm nrawm nrog maj mam tshee (3 ml hauv ib lub taub, 5 cartridges hauv ib lub hlwv, hauv cardboard ntim 1 blister, 3 ml hauv cartridge ua rau hauv Daim Npav Ceev mem phwj, hauv ib daim ntawv los qhia 5 lub pob syringe, txhua lub pob tseem muaj cov lus qhia rau kev siv ntawm Humalog Mix 50).

Kev sib xyaw ntawm 1 ml ntawm kev ncua kev kawm:

  • cov tshuaj ua kom muaj zog: insulin lispro - 100 Cov thoob ntiaj teb (ME),
  • Cov khoom siv pabcuam: sodium hydrogen phosphate heptahydrate, protamine sulfate, phenol kua, glycerol (glycerin), metacresol, zinc oxide, 10% sodium hydroxide tov thiab / lossis 10% hydrochloric acid tov, dej rau kev txhaj tshuaj.

Dosage daim ntawv

Kev daws rau iv thiab sc coj

tshuaj insulin lispro 100 IU

Cov zam: glycerol (glycerin) - 16 mg, metacresol - 3.15 mg, zinc oxide (q.s. rau Zn2 + 0.0197 μg), sodium hydrogen phosphate heptahydrate - 1.88 mg, hydrochloric acid daws 10% thiab / lossis sodium hydroxide daws 10% - q.s. mus txog pH 7.0-8.0, dej d / i - q.s. txog li 1 ml.

Kev ntsuas rau siv

Cov ntawv qhia ua lus, cov lus qhia rau kev siv

Cov koob tshuaj ntawm cov tshuaj tau teeb tsa ua ib tus zuj zus nyob ntawm qhov rhiab ntawm cov neeg mob mus rau tshuaj exogenous thiab lawv mob. Nws raug nquahu kom tswj cov tshuaj tsis pub dhau 15 feeb ua ntej lossis tom qab noj mov. Cov txheej txheem kev tswj hwm yog tus kheej. Ua li ntawd, tshuaj kub yuav tsum tau nyob theem theem.

Kev ua txhua hnub tuaj yeem sib txawv, muaj ntau qhov ntau rau 0.5-1 IU / kg. Nyob rau yav tom ntej, cov koob tshuaj txhua hnub thiab ib zaug ntawm cov tshuaj tau raug hloov kho nyob ntawm tus neeg mob metabolism thiab cov ntaub ntawv los ntawm ntau cov ntshav thiab cov zis ntsuas cov ntshav qabzib.

Kev tswj hwm kev siv tshuaj ntawm Humalog yog nqa tawm raws li kev txhaj tshuaj rau cov tshuaj tua kabmob. Kev txhaj tshuaj subcutaneous yog tsim nyob rau hauv lub xub pwg, pob tw, ncej puab lossis hauv plab, ntu hloov lawv thiab tsis pub siv qhov chaw ntau tshaj ib hlis ib zaug, thiab qhov chaw txhaj tshuaj yuav tsum tsis txhob muab zaws. Thaum ua cov txheej txheem, yuav tsum tau saib xyuas kom tsis txhob nkag rau hauv cov hlab ntshav.

Tus neeg mob yuav tsum tau kawm cov txheej txheem txhaj tshuaj kom raug.

Noj ntau dhau

Kev noj tshuaj ntau dhau hwv tuaj yeem ua rau ntshav qognrog los lus muaj mob nkees, tawm hws, ntuav, apathytshee hnyo, tsis hnov ​​mob, tachycardiamob taub hau. Nyob rau tib lub sijhawm, hypoglycemia tuaj yeem tshwm sim tsis yog hauv kev siv tshuaj ntau dhau, tab sis kuj yog qhov tshwm sim kev siv tshuaj insulin ntau ntxivtshwm sim los ntawm lub zog siv los noj. Ua raws li qhov mob hnyav ntawm lub qog ntshav qab zib, cov kev ntsuas tsim nyog yuav tau ua.

Kev sib txuam

Cov nyhuv hypoglycemic ntawm cov tshuaj yog txo, cov tshuaj cov thyroid hormones, GKS, beta 2-adrenergic agonists, tricyclic cov tshuaj tiv thaiv kev ntxhov siab, tshuaj kho mob, Diazoxide,,, derivatives phenothiazine, nicotinic acid.

Kev txo lub plawv tsis zoo ntawm cov tshuaj yog kho kom zoo anabolic tshuaj yuam, beta blockerstshuaj ethanol-muaj cov tshuaj Fenfluramine, tetracyclines, Guanethidine, MAO inhibitors, tshuaj tiv thaiv qhov ncauj hypoglycemic, salicylates, sulfonamides, ACE inhibitors, .

Cov nqe lus ntawm kev muag khoom

Cia rau cov neeg mob

Tsis txhob khov rau hauv tub yees ntawm qhov kub ntawm 2 ° txog 8 ° C.

Hnub tas sij hawm

Cov kev sib tw rau ATX Qib 4 code:

Yawg Hlob, Nruab Nrab HM, Sab Hauv SPP, Iletin II tsis tu ncua, Iletin kuv tsis tu ncua.

Kev Ntsuam Xyuas Kev Ntsuas Xyuas

Kev txheeb xyuas hauv feem ntau muaj qhov zoo. Nws pab pab them nyiaj rau qhov tsis muaj suab thaj hauv cov ntshav. Muaj ob peb xa mus rau cov kev mob tshwm sim.

Halogen nqi, yuav khoom qhov twg

Tus nqi ntawm Humalog 100 IU / ml cartridges 3 ml N5 sib txawv hauv qhov ntau ntawm 1730-2086 rubles rau pob. Koj tuaj yeem yuav cov tshuaj no hauv cov chaw muag tshuaj feem ntau hauv Moscow thiab lwm lub nroog.

  • Cov Tshuaj Yeeb Tshuaj Online hauv Tebchaws Russia
  • Cov Tshuaj Tshuaj Hauv Online Ukraine Ukraine
  • Cov chaw muag tshuaj online hauv Kazakhstan Kazakhstan

Humalog Mix25 daws 100 IU / ml cartridge 3 ml 5 pcs.

Humalog Mix25 raug tshem tawm ntawm 100 IU / ml hauv Kev Ceev Txiag Ceev syringe cwj mem 3 ml 5 pcs. Lilly Eli Lilly & Tuam Txhab

Kev txhaj tshuaj Humalog 100ME / ml cartridge 3 ml 5 pcs. Lilly Eli Lilly & Tuam Txhab

Lub Tsev Muag Tshuaj Dialog * luv nqi 100 rub. los ntawm kev cai tshaj tawm medside (rau kev txiav txim los ntawm 1000 rub.)

Humalog sib tov 50 cartridges. nrog rab koob xaum 100ME / ml 3ml QuickPen No. 5

Humalog Mix 50: cov lus qhia rau kev siv thiab tshuaj xyuas

Humalog Mix 50 yog qhov tshuaj hypoglycemic uas muaj kev sib xyaw ntawm luv luv thiab nruab nrab ntev insulin analogues.

Tso tawm daim ntawv thiab muaj pes tsawg leeg

Dosage form - raug tshem tawm rau kev tswj hwm subcutaneous: cov xim dawb, exfoliating nrog tsim ntawm nag lossis daus thiab pob tshab, yuav luag tsis muaj xim lossis xim tsis muaj xim tshaj plaws, tau nrawm nrawm nrog maj mam tshee (3 ml hauv ib lub taub, 5 cartridges hauv ib lub hlwv, hauv cardboard ntim 1 blister, 3 ml hauv cartridge ua rau hauv Daim Npav Ceev mem phwj, hauv ib daim ntawv los qhia 5 lub pob syringe, txhua lub pob tseem muaj cov lus qhia rau kev siv ntawm Humalog Mix 50).

Kev sib xyaw ntawm 1 ml ntawm kev ncua kev kawm:

  • cov tshuaj ua kom muaj zog: insulin lispro - 100 Cov thoob ntiaj teb (ME),
  • Cov khoom siv pabcuam: sodium hydrogen phosphate heptahydrate, protamine sulfate, phenol kua, glycerol (glycerin), metacresol, zinc oxide, 10% sodium hydroxide tov thiab / lossis 10% hydrochloric acid tov, dej rau kev txhaj tshuaj.

Cov chaw muag tshuaj

Cov Tshuaj Hauv Tshuaj

Humalog Mix 50 yog ib qho kev sib xyaw ua ke uas muaj 50% kev daws teeb meem ntawm lispro insulin (ib qho kev sib piv ntawm tib neeg cov tshuaj insulin) thiab 50% kev tiv thaiv kev ncua ntawm lispro insulin (qhov nruab nrab nruab nrab ntawm tib neeg insulin analog).

Cov cuab yeej tseem ceeb ntawm cov tshuaj yog cov kev cai ntawm cov metabolism hauv cov piam thaj. Nws kuj muaj cov teebmeem tawm tsam catabolic thiab anabolic rau ntau cov ntaub so ntswg ntawm lub cev. Hauv cov leeg nqaij ua raws li cov neeg ntawm Humalog Mix 50, cov ntsiab lus ntawm fatty acids, glycerol thiab glycogen nce, cov synthesis protein tau txhim kho, thiab kev noj ntawm cov amino acids yog nce. Qhov no txo ​​cov glycogenolysis, gluconeogenesis, lipolysis, ketogenesis, protein catabolism thiab kev tso tawm ntawm cov amino acids.

Nws tau tsim tsa hais tias insulin lyspro muaj qhov sib txawv ntawm tib neeg cov insulin, tab sis nws cov nyhuv loj hlob sai dua thiab siv sijhawm tsawg dua.

Tom qab kev tswj hwm nyob rau hauv daim tawv nqaij, qhov pib sai ntawm lyspro insulin kev txiav txim siab thiab qhov pib thaum ntxov ntawm nws cov haujlwm siab tshaj plaws tau sau tseg. Humalog Mix 50 pib kwv yees li ntawm 15 feeb tom qab txhaj tshuaj, yog li nws tuaj yeem siv txoj cai ua ntej noj mov (hauv 0-15 feeb), tsis zoo li cov neeg insulin zoo tib yam.

Kev txiav txim ntawm profile ntawm insulin lysproprotamine zoo ib yam li cov yeeb yam kev sib piv ntawm cov insulin isofan uas ib txwm muaj ntev li 15 teev.

Cov Tshuaj Pharmacokinetics

Lub pharmacokinetics ntawm Humalog Mix 50 yog txiav txim siab los ntawm cov khoom ntiag tug pharmacokinetic ntawm nws ob yam kev ua haujlwm.

Cov qib ntawm kev nqus thiab pib ntawm kev ua yeeb tshuaj yog nyob ntawm qhov chaw tswj hwm ntawm lub sijhawm (qog, hauv plab, pob tw) thiab nws cov koob tshuaj, nrog rau kev ua si ntawm tus neeg mob, nws lub cev kub thiab tso ntshav tawm.

Lyspro insulin tom qab kev tswj hwm kab mob hauv qab yog nqus tau sai. Qhov siab tshaj plaws hauv cov ntshav nce mus txog hauv 30-70 feeb.

Cov chaw muag tshuaj ntawm lysproprotamine insulin zoo ib yam li cov isofan insulin (nruab nrab insulin).

Hauv lub raum thiab hepatic tsis txaus, lyspro insulin yog nqus sai dua soluble tib neeg cov kua dej.

Kev ntsuas rau siv

Humalog Mix 50 siv rau kev kho mob ntshav qab zib mellitus xav tau kev kho mob insulin.

Humalog Mix 50, cov lus qhia rau kev siv: hom thiab siv ntau npaum li cas

Humalog Mix 50 npaj rau kev tswj hwm subcutaneous nkaus xwb. Koj tuaj yeem nkag mus rau nws tam sim ntawd ua ntej noj mov lossis tom qab noj mov. Cov koob tshuaj tau txiav txim los ntawm tus kws kho mob cais ib tus zuj zus rau txhua tus neeg mob, raws theem ntawm cov piam thaj hauv cov ntshav.

Koj tuaj yeem nkag mus rau cov tshuaj hauv plab, ncej, xub pwg lossis pob tw. Qhov chaw txhaj tshuaj yuav tsum tau hloov chaw kom, nyob rau tib qhov chaw, qhov kev ncua yog, yog tias ua tau, tswj tsis pub ntau tshaj ib hlis ib zaug.

Thaum qhia Humalog Mix 50, yuav tsum tau saib xyuas kom tsis txhob raug ncua kev nkag mus hauv lub lumen ntawm cov hlab ntshav. Tsis tas yuav zaws qhov chaw txhaj tshuaj tom qab koj txhaj tas.

Sab sij huam

Cov kev mob tshwm sim feem ntau pom nrog txhua hom tshuaj insulin yog hypoglycemia. Hauv cov xwm txheej hnyav, nws tuaj yeem ua rau tsis nco qab, hauv qee kis tshwj xeeb - ua rau ploj tuag.

Qee zaum cov kev fab tshuaj hauv zos tshwm sim: liab, khaus, lossis o ntawm thaj chaw txhaj tshuaj. Raws li txoj cai, cov xwm txheej no dhau mus ntawm nws tus kheej hauv ob peb hnub / lub lis piam. Hauv cov tib neeg mob, lawv tsis cuam tshuam nrog kev siv cov tshuaj insulin, tab sis raug mob, piv txwv li, los ntawm kev siv tshuaj tsis raug cai los yog tawv nqaij tom qab siv tshuaj ntxuav.

Cov tshuaj Insulin tsis tshua muaj mob ua rau lub cev tsis haum tshuaj, tab sis lawv yuav ua rau hnyav dua. Cov tsos mob hauv qab no tuaj yeem tshwm sim: ua pa luv, ua pa luv, ntshav tawm ntshav tsawg, tachycardia, nce tawm hws, dav dav pruritus. Yog tias muaj qhov ua txhaum fab hnyav, yuav tsum tau siv tshuaj los kho mob sai. Cov neeg mob zoo li no yuav xav tau kev kho kom tsis muaj zog lossis hloov pauv cov kua dej.

Nrog kev kho mob ntev, lipodystrophy yuav pib txhim kho ntawm qhov chaw txhaj tshuaj.

Cov teeb meem sib cais ntawm kev txhim kho ntawm edema tau paub, feem ntau nrog kev ceev ceev ntawm cov ntshav qabzib feem ntau tiv thaiv keeb kwm ntawm kev siv tshuaj insulin ntau dua nrog kev pib tsis txaus siab glycemic tswj.

Kev cuam tshuam rau kev muaj peev xwm tsav tsheb thiab cov txheej txheem nyuaj

Nrog rau kev txhim kho hypoglycemia, qhov kev txo qis ntawm qhov kev hloov pauv thiab kev mloog zoo yog qhov ua tau, uas ua rau muaj kev pheej hmoo ntawm kev raug mob thaum ua cov haujlwm phom sij, nrog rau kev tsav tsheb thiab ua haujlwm nrog cov txheej txheem nyuaj. Hauv qhov no, kev ceev faj yuav tsum tau siv, tshwj xeeb tshaj yog nyob rau cov neeg mob uas cov tsos mob ua ntej ntawm lub qog ntshav qab zib tsis tuaj lossis mob me. Xws li kev txhim kho ntshav nce siab ntau dhau, qhov ua tau ntawm kev nqis tes ua haujlwm nrog rau qhov xwm txheej tsis zoo yuav tsum raug ntsuas.

Nrog lub siab ua haujlwm tsis zoo

Thaum lub siab ua haujlwm tsis txaus siab, Humalog Mix 50 yuav tsum tau siv nrog ceev faj, nyob rau hauv kev saib xyuas ntawm tus kws kho mob, vim tias qhov xav tau cov tshuaj insulin yuav poob vim qhov txo qis hauv lub peev xwm gluconeogenesis thiab txo qis hauv cov tshuaj insulin metabolism. Txawm li cas los xij, nyob rau hauv ntev daim siab tsis ua hauj lwm, nce insulin tsis kam yog ua tau, uas yuav tsum tau nce ntxiv ntawm koob tshuaj.

Yeeb tshuaj sib cuam tshuam

Cov nyhuv hypoglycemic ntawm Humalog Mix 50 yog txo los ntawm beta 2 -adrenergic agonists (piv txwv li, terbutaline, salbutamol, ritodrin), glucocorticosteroids, phenothiazine derivatives, thiazide diuretics, iodine-muaj cov thyroid hormones, tshuaj tiv thaiv qhov ncauj, nicotinazide, isotonazole, dio isoleazole, isotonazole, diodosoleole, diodazole, diozin, dioazin, isotonazole,

Hypoglycemic txiav txim Humalog Mix 50 txhim khu qhov ncauj hypoglycemic agents, sulfa tshuaj tua kab mob, anabolic steroids, beta-blockers, angiotensin converting enzyme inhibitors (captopril, enalapril), angiotensin II receptor antagonists, tej antidepressants (monoamine oxidase inhibitors), salicylates (e.g., acetylsalicylic acid), tetracyclines , ethanol thiab ethanol-muaj npaj, octreotide, guanethidine, fenfluramine.

Nrog rau kev siv cov tshuaj ntawm thiazolidinedione pab pawg, muaj kev pheej hmoo ntawm kev txhim kho edema thiab lub plawv tsis ua haujlwm, tshwj xeeb tshaj yog rau cov neeg mob uas muaj cov kab mob ntawm cov hlab plawv thiab muaj cov kev pheej hmoo ua rau mob plawv tsis ua haujlwm.

Reserpine, clonidine thiab beta-blockers tuaj yeem npog cov tsos mob ntawm kev mob ntshav qab zib uas tau tsim nrog kev siv Humalog Mix 50.

Qhov sib cuam tshuam ntawm Humalog Mix 50 nrog rau lwm cov tshuaj insulin tsis tau kawm.

Txoj hauv kev siv lwm cov tshuaj thaum kho cov ntshav qab zib yuav tsum pom zoo nrog koj tus kws kho mob.

Analogues Humalog Mix 50 yog NovoMiks 30 Penfill, NovoMiks 30 FleksPen, NovoMiks 50 FleksPen, NovoMiks 70 FleksPen, Insulin aspart NovoRapid Penfill, NovoRapid FleksPen, Lantus SoloSTAR, Tudzheo SoloSTAR, Apidra, Homolong 40, insulin detemir, insulin lispro, Rosinsulin, Homo 40 thiab lwm tus.

Cov lus thiab cov xwm txheej ntawm kev cia

Khaws tsis ncav cuag cov menyuam yaus, tiv thaiv los ntawm ncaj qha tshav ntuj thiab tshav kub, ntawm qhov kub ntawm 2-8 ° C. Tsis khov. Cov khoom lag luam hauv kev siv tuaj yeem khaws cia hauv qhov kub txog 30 ° C, tab sis tsis pub dhau 28 hnub.

Txee lub neej yog 3 xyoos.

Ib qhov tsis tseem ceeb hauv lub neej ntawm txhua tus mob ntshav qab zib yog kua cwj mem rau insulin. Qhov kev tsim no ua rau lub neej yooj yim rau ntau lab tus neeg mob thoob ntiaj teb. Tom qab txhua tus, yog tias muaj cwj mem li ntawm tes, tus neeg mob yuav tsis tas yuav tsum tau pabcuam kev pabcuam ntawm cov kws saib mob kom tau txais cov koob tshuaj tsim nyog ntawm insulin. Qhov dhia tsawg tshaj plaws hauv qab zib tuaj yeem ua rau muaj kev phom sij, yog li kev yuav cov tshuaj txhaj yog thawj kauj ruam mus tas lub neej.

Dab tsi ntawm cov koob txhaj tshuaj muaj?

Thaum muaj ntshav qab zib mellitus, cov txheej txheem metabolic maj mam tshwm sim hauv lub cev vim qhov ua haujlwm tsis zoo hauv cov tshuaj tua kab mob ntawm cov kua dej. Kev kho mob ntshav qab zib hom 1 cuam tshuam nrog kev tswj hwm ntawm kev ua haujlwm qub. Lub koob txhaj tshuaj yog tsim los tswj kev siv tshuaj sai rau hauv lub cev thaum muaj xwm txheej ceev. Muaj ntau hom kev txhaj tshuaj:

  • Cov koob txhaj raws cov koob uas tshem tau. Qhov peculiarity ntawm kev ua haujlwm ntawm tus cwj mem yog tias tus neeg mob xav tau ntxig ib rab koob tshiab txhua lub sijhawm ua ntej yuav noj tshuaj thiab tswj hwm nws.
  • Cov koob txhaj tshuaj uas muaj koob xav ua. Hom cuab yeej zoo li no tau qhia tias rab koob muaj lub npe hu ua "cheeb tsam tuag", uas ua rau txo qis kev phom sij.

Yuav ua li cas xaiv cov xwj xaum xaum rau kev insulin?

Txhua rab phom insulin rau cov neeg mob ntshav qab zib tau tsim los ua kom tau raws li txhua yam ntawm cov neeg mob ntshav qab zib. Lub piston ntawm tus kov yuav tsum ua nyob rau hauv txoj kev uas nws yooj yim tshaj plaws los siv cov koob txhaj tshuaj yam tsis muaj qhov mob. Thaum muas lub insulin syringe, nws yog qhov tseem ceeb yuav tsum them sai sai rau cov nplai ntawm lub cuab yeej. Koj yuav tsum xaiv rab koob xaim hluav taws nyob hauv qhov hnyav, nruab nrog lub suab nrov uas tau muab thaum txhaj cov tshuaj hormones.

Tus kws kho mob xaiv cov tshuaj ntau npaum li cas, feem ntau lawv ntaus nqi 0.5 rau cov menyuam yaus, thiab 1 koog rau cov neeg laus.

"Protafan NM Penfil".

Kev siv raug tso cai tsuas yog rau kev txhaj tshuaj subcutaneous, nws yog txwv tsis pub nkag rau qhov quav. Nws raug nquahu kom hloov chaw txhaj tshuaj txhua zaus. Qhov kev ncua yog muab cais ua pawg pab pawg insulin nrog lub sijhawm ua haujlwm ntev. Muaj nyob hauv 5 daim cartridges. Tom qab txhua tus siv Protafan, nws yog ib qho tseem ceeb uas yuav tsum tau ua kom paub tseeb tias cov koob tau tawm ntawm rab koob txhaj tshuaj. Txwv tsis pub, cov tshuaj yuav xau, uas yog txaus ntshai los ntawm kev hloov nws cov kev xav.

Tshuaj yaug R

Qhov kev npaj Rinsulin NPH npaj rau kev siv rov ua haujlwm. Koj tsis tuaj yeem rov ntxiv cov tshuaj yog tias nws raug rau khov. Tau txais cov khoom los ntawm synthesis, muaj lub sijhawm luv luv ntawm kev ua. Tshaj rau siv nrog RinAstra kov. Nws tsuas ua haujlwm yog tias cov tshuaj tau nce mus txog chav kub.

"Cia nqa-N Royal"

Txhawm rau tswj cov tshuaj insulin, koj xav tau Wozulim Pen Royal insulin injector. Cov tshuaj ua ke nruab nrab thiab luv lub sij hawm hluavtaws cov tshuaj insulin. Nws raug nquahu kom xyuam xim nrog rau cov neeg mob uas mob raum. Nws tuaj yeem siv thaum cev xeeb tub, cov tshuaj tsis hla tus kheej. Lub sijhawm tiv thaiv kev rau ncua yog 24 teev.

Rosinsulin

Cov ntaub ntawv rov tuaj yeem siv tus cwj mem "Rosinsulin Comfort Pen" muaj cov ntaub ntawv cov tawv tawv hnyav. Tus neeg siv tuaj yeem hloov kho qhov koob tshuaj, cov cuab yeej muaj cov log muag muag rau ib txheej ntawm cov cuab yeej. Cov cuab yeej muaj qhov kev faib tawm meej nrog nce mus txog 60 ib pawg. Qhov tsim nyog rau cov neeg tsis pom kev zoo. Tus cwj mem ciav yog tsim los rau siv ntau nrog kev muaj peev xwm hloov lub pob txha. Muaj txoj hauv kev hloov lub koob tsis haum. Xws li yog kev qhia ua.

BiomaticPen

Tus kov coj txawv ntawm lwm cov tuam ntxhab hauv kev xuas tes kom zoo dua nrog rab koob nyias, uas txo qhov mob tsawg kawg nkaus. "BiomaticPen" yog qhov tsim nyog rau, uas tuaj yeem muas hauv khw tshwj xeeb lossis hauv cov ntawv teev online. Cov cuab yeej muaj lub tshuab hluav taws xob tsis zoo no feem uas qhia txog qhov ntau npaum li cas ntawm cov tshuaj. Ua ntej koj nkag mus rau "Biosulin", koj yuav tsum nyeem cov lus qhia.

HumaPen Savvio

Cov koob txhaj tshuaj "Humapen Savvio" yog rau qhov ua kom xis nyob thiab tsis muaj mob ntawm cov tshuaj insulin rau cov neeg mob ntshav qab zib. Qhov txawv txav tshwj xeeb yog qhov tsim qauv ntawm cov koob tshuaj txhaj tshuaj. Cov cuab yeej siv hluav taws xob yog txhuas, tiv taus cov khoom siv los tiv thaiv kev tawg thiab khawb hauv rooj plaub. Ua kom tiav nrog ib rooj plaub tuaj hauv hnab tshos tuaj yeem ntim tau li 6 koob. Muaj ob peb xim. Nruab nrog lub tshuab xa khoom siv thiab cov tshuab txiav txim siab koob tshuaj.

Autopen classic

Autopen Classic rov siv cov phom insulin yog sib xws nrog ntau hom tshuaj insulin, xws li Biosulin, Rosinsulin thiab lwm yam. Cov cuab yeej Avtopen tseem tuaj yeem siv nrog txhua yam koob uas xav tau. Lub Autopen syringe cwj mem suav nrog: lub tshuab ua kom sib haum, rooj plaub muag, 3 rab koob koob (8 hli) thiab lub cuab yeej nws tus kheej. Nws raug nquahu kom koj nyeem cov lus qhia ua ntej siv.

Cov tsos ntawm cov tshuaj insulin ua rau lub neej yooj yim dua rau cov neeg mob ntshav qab zib, thiab SoloStar koob txhaj tshuaj tsis muaj qhov zam. Cov no yog cov tshuaj insulin pov tseg. Tsim rau kev siv tus kheej nkaus xwb, kom tsis txhob muaj kev pheej hmoo kis mob. Txhua qhov kev txhaj tshuaj yuav tsum tau siv cov koob tshiab, uas yuav tsum tau txhaj tso ua ntej kev qhia ntawm insulin. Tom qab siv tas, tus kov raug kaw nrog lub hau, rab koob tau muab tshem tawm ua ntej. Nws yog siv nrog insulin "Insuman Comb 25".

Humulin Quick cwj mem

Lub QuickPen koob txhaj tshuaj tsis tau zoo tshaj nyob rau hauv muaj koob npe rau lwm cov tuam ntxhab. Haum rau cov poj niam cev xeeb tub uas muaj ntshav qab zib hom 2. Autopen classic syringe mem thiab Humulin Rapid yog cov thawj coj hauv khw. Tsis zoo li thawj qhov kev xaiv, QuickPen kov yog kev tso pov tseg, rov ua haujlwm. Tom qab txhua tus siv ntawm Humulin, lub cuab yeej raug muab pov tseg, tus xaum yuav tsum tau hloov pauv. Cov khoom siv suav nrog 5 xaum ntawm 3 ml ntawm kev daws hauv txhua.

Cov chaw muag tshuaj

Cov chaw muag tshuaj ntawm lyspro insulin yog pom los ntawm kev nqus sai thiab lub ncov hauv cov ntshav 30 mus rau 70 feeb tom qab txhaj tshuaj subcutaneous. Lyspro insulin muaj qhov pib ua haujlwm sai (kwv yees li 15 feeb tom qab txhaj tshuaj subcutaneous), uas tso cai rau cov tshuaj kom sai ua ntej noj mov (0 txog 15 feeb ua ntej noj mov), tsis zoo li cov tshuaj lom luv luv ntawm insulin, siv 30 mus rau 45 feeb ua ntej noj mov Cov. Lyspro insulin muaj lub sijhawm luv dua (2 mus rau 5 teev) piv nrog tib neeg cov tshuaj insulin.

Lub sijhawm ua haujlwm ntawm cov insulin lispro tuaj yeem sib txawv hauv cov neeg mob sib txawv lossis txawv sijhawm hauv tib tus neeg mob thiab nyob ntawm koob tshuaj, chaw txhaj tshuaj, ntshav ntshav, kub cev thiab kev tawm dag zog.

Thaum cov tshuaj insulin raug txhaj, lyspro qhia tau tias kev nqus sai dua li piv nrog kev lom neeg tib neeg cov kua dej hauv cov neeg mob raum thiab mob hepatic tsis txaus, ntxiv rau kev tshem tawm sai dua rau cov neeg mob uas tsis muaj kabmob hepatic. Hauv cov neeg mob uas muaj hom 2 mob ntshav qab zib mellitus nrog ntau lub raum ua rau lub raum ua haujlwm, qhov txawv ntawm cov tshuaj lyspro insulin thiab insulin luv luv feem ntau ua rau thiab tsis nyob ntawm kev mob raum.

Glucodynamic lo lus teb rau lyspro insulin tsis yog nyob ntawm kev ua haujlwm tsis ua haujlwm ntawm lub siab thiab lub raum.

Lyspro insulin tau pom tias yog ua kom sib luag rau tib neeg cov tshuaj insulin, tab sis nws cov kev ua tshwm sim sai dua thiab kav rau lub sijhawm luv.

Lyspro insulin yog ib qho DNA sib txuas ntawm tib neeg cov tshuaj insulin. Nws txawv ntawm tib neeg cov insulin hauv kev rov qab hloov zuj zus ntawm cov amino acids ntawm txoj haujlwm 28 thiab 29 ntawm cov insulin B saw.

Kev ua tseem ceeb ntawm insulin lyspro yog txoj cai ntawm cov metabolism hauv qabzib. Tsis tas li ntawd, nws muaj anabolic thiab anti-catabolic cuam tshuam rau ntau cov ntaub so ntswg lub cev. Hauv cov leeg nqaij, muaj qhov nce ntawm cov ntsiab lus ntawm glycogen, fatty acids, glycerol, kev nce ntawm synthesis protein thiab nce ntxiv ntawm kev noj cov amino acids, tab sis tib lub sijhawm muaj glycogenolysis, gluconeogenesis, ketogenesis, lipolysis, protein catabolism thiab kev tso tawm ntawm cov amino acids.

Cov chaw muag tshuaj profile ntawm insulin lyspro hauv cov menyuam yaus zoo ib yam li ntawd rau cov laus.

Cov ntaub ntawv dav dav thiab thaj chaw muag tshuaj

Humalog yog nyob rau hauv daim ntawv ntawm ncua kev kawm lossis kev txhaj tshuaj. Kev raug tshem tawm yog txais tos nyob rau hauv cov neeg dawb thiab ib qho nyiam nyiam lub siab. Txoj kev daws teeb meem tsis muaj xim thiab tsis ntxhiab, pob tshab.

Lub ntsiab ntawm cov khoom muaj pes tsawg leeg yog cov tshuaj insulin.

Ntxiv rau nws, cov khoom xyaw xws li:

  • dej
  • metacresol
  • zinc oxide
  • glycerol
  • sodium hydrogen phosphate heptahydrate,
  • Cov kua sodium hydroxide.

Cov khoom lag luam raug muag hauv 3 ml cartridges. Cartridges yog nyob hauv Quicken, 5 daim ib pob.

Tsis tas li ntawd, muaj ntau yam yeeb tshuaj, uas suav nrog kev hais luv luv ntawm cov tshuaj insulin thiab kev txwv tsis pub tshuaj. Lawv hu ua Humalog Mix 25 thiab Humalog Mix 50.

Cov tshuaj Insulin Lizpro yog ib qho tshuaj yeeb yaj kiab thiab tau tsim los ntawm tib qho kev ua. Nws pab txhawm rau ua kom nce tus nqi ntawm cov piam thaj. Cov tshuaj ua yeeb yaj kiab ua haujlwm ntawm lub cell cell, vim tias cov piam thaj hauv cov ntshav nkag mus rau cov ntaub so ntswg thiab muab faib rau hauv lawv. Nws kuj txhawb nqa ua kom cov protein ua haujlwm zoo.

Cov tshuaj no yog tus cwj pwm los ntawm kev ua sai. Cov nyhuv tshwm nyob rau hauv ib lub hlis twg ntawm ib teev tom qab txhaj tshuaj. Tab sis nws mob tsawv rau ib pliag. Rau ib nrab-lub neej ntawm cov tshuaj yeeb yaj kiab, li 2 teev xav tau. Qhov siab tshaj plaws rau lub sijhawm yog 5 teev, uas cuam tshuam los ntawm qee qhov yam ntxwv ntawm tus neeg mob lub cev.

Kev taw qhia thiab contraindications

Qhov taw qhia rau kev siv cov tshuaj insulin-muaj yog:

  • (nyob rau hauv muaj intolerance mus rau lwm yam ntau yam ntawm cov kua dej),
  • (yog tias kho nrog lwm cov tshuaj tsis muaj txiaj ntsig)
  • npaj kev pab rau kev phais mob

Hauv cov xwm txheej no, yuav tsum tau kho cov tshuaj insulin. Tab sis tib lub Humalog yuav tsum tau tsa los ntawm tus kws kho mob tom qab kawm txog daim duab ntawm tus kab mob. Cov tshuaj no muaj qee yam contraindications. Koj yuav tsum xyuas kom meej tias lawv tsis tuaj, txwv tsis pub muaj kev pheej hmoo ntawm cov kev mob tshwm sim.

Cov no suav nrog:

  • kev tshwm sim (los yog qhov tshwm sim ntawm qhov tshwm sim),
  • fab rau cov muaj pes tsawg leeg.

Nrog rau cov ntsej muag no, tus kws kho mob yuav tsum xaiv lwm yam tshuaj sib txawv.Ceev faj kuj tseem ceeb yog tias tus neeg mob muaj qee cov kab mob ntxiv (kab mob ntawm lub siab thiab lub raum), vim tias vim lawv, lub cev xav tau cov tshuaj insulin tuaj yeem ua kom tsis muaj zog. Raws li, cov neeg mob zoo li no yuav tsum kho cov tshuaj ntau ntxiv.

Cov Neeg Mob Tshwj Xeeb thiab Cov Lus Qhia

Thaum siv Humalog, qee qhov yuav tsum tau ceev faj txog qhov tshwj xeeb ntawm cov neeg mob. Lawv lub cev yuav nkag siab dhau los cuam tshuam txog cov tshuaj insulin, yog li koj yuav tsum tau ua tib zoo saib xyuas.

Ntawm lawv yog:

  1. Cov poj niam thaum cev xeeb tub. Raws txoj kev xav, kev kho mob ntshav qab zib hauv cov neeg mob no tau tso cai. Raws li kev tshawb pom, cov tshuaj tsis cuam tshuam rau kev txhim kho ntawm tus me nyuam hauv plab thiab tsis ua rau muaj kev rho menyuam hauv plab. Tab sis nws yuav tsum tau yug los rau hauv lub siab tias lub sijhawm no cov theem ntawm cov piam thaj hauv cov ntshav tuaj yeem sib txawv ntawm cov sijhawm sib txawv. Qhov no yuav tsum raug tswj kom tsis txhob muaj qhov tsis xav ua yam tsis zoo.
  2. Saib xyuas niam cov txiv. Kev nkag mus ntawm cov tshuaj insulin rau hauv niam mis tsis yog qhov kev phom sij rau tus menyuam mos. Qhov khoom siv no muaj cov keeb kwm protein thiab nqus tau ntawm txoj hnyuv zom zaub mov. Qhov ceeb toom tsuas yog tias cov poj niam uas ua raws li kev noj zaub mov zoo yuav tsum yog nyob ntawm zaub mov noj.

Rau cov menyuam yaus thiab cov laus hauv qhov tsis muaj teeb meem kev noj qab haus huv, tsis muaj kev saib xyuas tshwj xeeb. Cov tshuaj Humalog yog qhov haum rau lawv txoj kev kho mob, thiab tus kws kho mob yuav tsum xaiv qhov ntau npaum li cas los ntawm cov yam ntxwv ntawm chav kawm ntawm tus kabmob.

Kev siv ntawm Humalog yuav tsum muaj qee qhov kev xav hauv kev sib raug rau qee yam kabmob sib kis.

Cov no suav nrog:

  1. Kev ua txhaum nyob rau hauv daim siab. Yog tias qhov kev ua haujlwm ntawm lub cev ua haujlwm tsis zoo tshaj li qhov tsim nyog, tom qab ntawd cov nyhuv ntawm cov tshuaj rau nws yuav dhau mus, uas ua rau muaj teeb meem, nrog rau kev txhim kho hypoglycemia. Yog li ntawd, nyob rau hauv qhov muaj kab mob siab, qhov kev noj tshuaj ntawm Humalog yuav tsum raug txo kom tsawg.
  2. Teeb meem lub raum ua haujlwm. Yog tias lawv nyob hauv, nws tseem muaj qhov txo qis hauv lub cev xav tau cov tshuaj insulin. Hauv kev hais txog qhov no, koj yuav tsum ua tib zoo suav seb puas noj ntau npaum li cas thiab saib xyuas txoj kev kho. Lub xub ntiag ntawm cov teeb meem zoo li no yuav tsum muaj kev tshuaj xyuas lub raum ib qho zuj zus.

Humalog muaj peev xwm ua rau cov ntshav qis, vim tias qhov ceev ntawm cov tshuaj tiv thaiv thiab lub peev xwm mloog zoo yog cuam tshuam.

Kiv taub hau, tsis muaj zog, tsis meej pem - tag nrho cov yam ntxwv no tuaj yeem cuam tshuam kev ua haujlwm ntawm tus neeg mob. Kev ua ub no uas xav tau kev nrawm thiab kev xav yuav ua tsis tau rau nws. Tab sis cov tshuaj nws tus kheej tsis cuam tshuam rau cov ntsej muag no.

Tej yam kev mob tshwj xeeb

Hloov chaw ntawm tus neeg mob mus rau lwm hom lossis hom tshuaj insulin yuav tsum tau ua raws li kev saib xyuas mob nkeeg nruj me ntsis. Cov kev hloov hauv kev ua, hom (tsim tawm), hom (piv txwv, tsis tu ncua, NPH, Daim kab xev), hom (tsiaj, tib neeg, tib neeg insulin analogue) thiab / lossis cov qauv kev tsim tawm (DNA recombinant insulin lossis insulin ntawm keeb kwm tsiaj) yuav xav tau hloov pauv cov koob tshuaj.

Cov mob uas cov cim qhia ntxov ntawm hypoglycemia yog qhov tsis tseem ceeb thiab tsis tshua hais tawm muaj xws li txuas ntxiv cov ntshav qab zib mellitus, kev kho mob insulin ntau ntxiv, kab mob hauv cov kab mob ntshav qab zib mellitus, lossis cov tshuaj noj, xws li beta-blockers.

Hauv cov neeg mob hypoglycemic tshua tom qab hloov los ntawm tsiaj los ntawm cov tshuaj insulin rau tib neeg insulin, cov tsos mob thaum ntxov ntawm hypoglycemia yuav tsis tshua pom los yog txawv ntawm cov kev paub dhau los ntawm lawv cov insulin yav dhau los. Kev tswj tsis tau tus mob hypoglycemic lossis hyperglycemic tshua tuaj yeem ua rau tsis nco qab, tsis nco qab, lossis tuag.

Kev noj tshuaj tsis txaus lossis tsis ua haujlwm ntawm kev kho mob, tshwj xeeb tshaj yog muaj cov kab mob ntshav qab zib insulin-tuaj yeem ua rau hyperglycemia thiab ntshav qab zib ketoacidosis, cov xwm txheej uas yuav tsim kev phom sij rau tus neeg mob.

Txoj kev xav tau cov tshuaj insulin tuaj yeem txo qis rau cov neeg mob raum tsis ua haujlwm, zoo li nyob rau hauv cov neeg mob siab tsis ua hauj lwm zoo li txo qis hauv gluconeogenesis thiab insulin metabolism. Txawm li cas los xij, nyob rau hauv cov neeg mob mob siab tsis ua haujlwm ntev, muaj peev xwm tiv thaiv insulin ntau dua tuaj yeem ua rau muaj kev nce ntxiv hauv insulin.

Qhov xav tau ntawm cov tshuaj insulin tuaj yeem nce nrog cov kis kab mob, kev ntxhov siab hauv lub siab, nrog qhov nce ntawm cov carbohydrates hauv cov zaub mov noj.

Yog hais tias tus neeg mob lub cev qoj ib ce ntau zog los yog pauv noj zaub mov zoo ces kuj tseem yuav tsum tau txhaj koob tshuaj. Kev tawm dag zog tam sim ntawd tom qab noj mov tas yuav ua rau muaj ntshav qab zib tsawg dua. Ib qhov tshwm sim ntawm lub pharmacodynamics ntawm kev ua yeeb yam sai insulin analogues yog tias yog tias cov ntshav qog ntshav qab zib, tom qab ntawd nws tuaj yeem txhim kho tom qab txhaj tshuaj dua li thaum txhaj cov tshuaj tiv thaiv tib neeg cov tshuaj insulin.

Tus neeg mob yuav tsum tau ceeb toom tias yog tias tus kws kho mob tau sau ib qho tshuaj insulin nrog kev sib xyaw ntawm 40 IU / ml hauv ib lub vial, ces cov tshuaj insulin yuav tsum tsis txhob noj cov tshuaj cartridge nrog cov tshuaj insulin ntawm 100 IU / ml siv koob txhaj rau insulin nrog rau 40 IU / ml.

Yog tias tsim nyog, noj lwm cov tshuaj thooj txhij nrog cov tshuaj

Mob ntshav qab zib mellitus hauv cov neeg laus thiab cov menyuam yaus, xav tau kev kho tshuaj insulin kom muaj cov suab thaj hauv lub cev.

Kev piav qhia ntawm Insulin Humalog

Luv insulin Humalog yog tsim los ntawm Fabkis lub tuam txhab Lilly Fabkis, thiab cov qauv qauv ntawm nws tso tawm yog qhov pom tseeb thiab tsis muaj kob, muab ntim rau hauv tshuaj ntsiav lossis lub taub hau. Lub tom kawg tuaj yeem muag ob qho tib si ua ib feem ntawm kev npaj tau ceev mem hluav taws xob, lossis cais rau tsib ampoules rau 3 ml hauv ib lub hlwv. Raws li lwm txoj hauv kev, Humalog Mix npaj ua tau tsim nyob rau hauv daim ntawv ntawm kev ncua rau kev tswj hwm subcutaneous, qhov ib txwm Humalog Mix tuaj yeem muab tshuaj nrog dej.

Lub hauv paus ua haujlwm tseem ceeb ntawm Humalog yog insulin lispro - ob-theem tshuaj ntawm qhov kub siab ntawm 100 IU rau 1 ml ntawm kev daws, qhov kev ua ntawm uas tau tswj hwm los ntawm cov khoom siv hauv qab no ntxiv:

  • glycerol
  • metacresol
  • zinc oxide
  • sodium hydrogen phosphate heptahydrate,
  • hydrochloric acid daws,
  • Cov kua sodium hydroxide.

Los ntawm qhov pom ntawm cov pab pawg soj ntsuam thiab chaw muag tshuaj, Humalog yog hais txog cov yeeb yam ntawm cov neeg ua haujlwm insulin, tab sis txawv ntawm lawv hauv cov kab rov qab ntawm cov amino acids. Lub luag haujlwm tseem ceeb ntawm cov tshuaj yog tswj hwm kev nqus ntawm cov piam thaj, txawm hais tias nws tseem muaj cov yam ntxwv ntawm anabolic. Pharmacologically, nws ua raws li hauv qab no: hauv cov leeg nqaij, nce qib ntawm glycogen, fatty acids thiab glycerol yog kho, nrog rau kev nce ntxiv hauv cov concentration ntawm cov protein thiab kev noj cov amino acids los ntawm lub cev. Nyob rau hauv tib yam, cov txheej txheem xws li glycogenolysis, gluconeogenesis, lipolysis, protein catabolism, thiab ketogenesis qeeb.

Cov kev tshawb fawb pom tau tias hauv cov neeg mob uas muaj ob hom mob ntshav qab zib mellitus tom qab noj mov, cov ntshav qab zib nce tsawg dua sai dua yog tias Humalog siv es tsis txhob siv lwm cov tshuaj insulin.

Nws yog ib qho tseem ceeb kom nco ntsoov tias yog tias tus mob ntshav qab zib ib txhij tau txais cov tshuaj insulin luv luv thiab basal insulin, nws yuav tsim nyog kho qhov ntau npaum li cas ntawm ob qho tshuaj thawj thiab thib ob kom tau txais txiaj ntsig zoo tshaj plaws. Dua li ntawm qhov tseeb tias Humalog yog cov insulins luv luv ua haujlwm, lub sijhawm kawg ntawm nws cov kev txiav txim siab raug txiav txim los ntawm ntau yam rau txhua tus neeg mob:

  • tsuas tshuaj
  • chaw txhaj tshuaj
  • lub cev kub
  • kev siv lub cev
  • zoo ntawm cov ntshav txaus.

Nyias, nws yog tsim nyog sau cia qhov tseeb tias Humalog insulin zoo sib xws rau tib neeg cov ntshav qab zib thiab kho cov menyuam yaus lossis cov hluas. Nws tseem tsis hloov pauv tias cov nyhuv ntawm cov tshuaj tsis yog nyob ntawm qhov yuav tshwm sim ntawm lub raum lossis lub siab ua haujlwm hauv tus neeg mob, thiab thaum ua ke nrog cov koob tshuaj sulfonylurea ntau, cov qib ntawm glycated hemoglobin ho txo ​​qis. Feem ntau, tau muaj tus cim txo qis hauv cov neeg mob nocturnal hypoglycemia, los ntawm cov neeg mob ntshav qab zib feem ntau raug kev txom nyem yog tias lawv tsis noj cov tshuaj uas tsim nyog.

Cov yam ntxwv ntawm Humalog insulin qhia hauv cov lej zoo li qhov no: qhov pib ntawm kev nqis tes yog 15 feeb tom qab txhaj, lub sijhawm ua haujlwm yog los ntawm ob txog tsib teev. Ntawm ib sab tes, lub sijhawm ua haujlwm zoo ntawm cov tshuaj qis dua li ntawm cov tshuaj sib piv, thiab ntawm qhov tod tes, nws tuaj yeem siv tsuas yog 15 feeb ua ntej noj mov, thiab tsis yog 30-35, zoo li lwm qhov insulins.

Cov lus thiab cov xwm txheej ntawm kev cia

Cov xov tooj ntawm tes yuav tsum muab tso rau qhov chaw uas cov me nyuam nkag tsis tau rau hauv lub tub yees zoo, ntawm qhov kub ntawm +2 txog +8 degrees Celsius. Cov txheej txheem txee lub neej yog ob xyoos. Yog tias cov pob twb tau qhib lawm, cov tshuaj insulin no yuav tsum ceev cia hauv chav sov li ntawm +15 txog +25 degrees Celsius.

Kev saib xyuas yuav tsum tau ua kom ntseeg tau tias cov tshuaj tsis ua kom sov thiab tsis nyob rau hauv tshav ntuj. Thaum pib siv, lub txee lub neej txo mus rau 28 hnub.

Cov tshuaj tiv thaiv ncaj qha ntawm Humalog yuav tsum xav txog tag nrho cov tshuaj insulin npaj rau cov ntshav qab zib hauv txoj kev zoo sib xws. Ntawm cov muaj npe nrov tshaj plaws yog Actrapid, Vosulin, Gensulin, Insugen, Insular, Humodar, Isofan, Protafan thiab Homolong.

LUS QHIA RAU KEV SIV KHUAJ KHO MOB KHO MOB

Lub Npe Tsis Muaj Npe International

Txhaj Tshuaj 100 IU / ml 3 ml

1 ml ntawm kev daws

cov tshuaj nquag - insulin lispro 100 IU / ml,

kev zam: metacresol, glycerin, zinc oxide, sodium hydrogen phosphate, hydrochloric acid 10% txhawm rau kho cov pH, sodium hydroxide 10% kev daws teeb meem kom kho cov pH, dej rau kev txhaj tshuaj.

Cov kua ntshiab tsis muaj kua

Tshuaj kho mob ntshav qab zib. Cov tshuaj insulin thiab kev ua haujlwm sai.

Tsis siv neeg hloov xov tooj code A10AV04

Qhov pib ntawm lyspro insulin tom qab kev tswj hwm subcutaneous yog kwv yees li 15 feeb, qhov siab tshaj yog los ntawm 30 txog 70 feeb, lub sijhawm ua ntawm 2 mus rau 5 teev. Lub sijhawm ua haujlwm ntawm lyspro insulin tuaj yeem sib txawv raws li kev txhaj tshuaj, chaw txhaj tshuaj, ntshav ntshav, ntsuas kub, kev ua haujlwm ntawm tus neeg mob, thiab lwm yam. Hauv cov ntshav, lyspro insulin khi rau alpha-beta globulins. Nquag, kev khi yog tsuas yog 5-25%, tab sis nws tuaj yeem nce ntxiv ntawm qhov muaj cov tshuaj tiv thaiv uas tshwm sim thaum txoj kev kho mob. Qhov ntim ntawm kev faib tawm ntawm cov tshuaj insulin lyspro zoo ib yam rau tib neeg thiab cov nyiaj yog 0.26 - 0.36 l / kg. Lyspro insulin metabolism tshwm sim hauv daim siab thiab lub raum. Hauv lub siab, thaum lub sijhawm kuaj ntshav ib zaug, nce txog 50% ntawm qhov rho tawm yog qhov tsis ciaj sia, hauv lub raum cov tshuaj hormones yog lim hauv cov glomeruli thiab rhuav tshem hauv cov tubules (txog 30% ntawm qhov tshuaj nqus). Tsawg dua li 1.5% ntawm lyspro insulin yog tawm hauv cov zis tsis hloov pauv. Ib nrab-lub neej yog nyob ntev li 1 teev.

Humalog® yog ib qho piv txwv ntawm tib neeg cov kua dej thiab txawv ntawm nws tsuas yog rov qab ua ntu zus ntawm cov kab muag thiab lysine amino acid seem ntawm txoj haujlwm 28 thiab 29 ntawm cov kab insulin B. Lub luag haujlwm tseem ceeb ntawm Humalog® yog kev tswj ntawm cov metabolism hauv qabzib. Tsis tas li ntawd, txhua qhov insulins muaj qhov sib txawv anabolic thiab anti-catabolic rau ntau cov ntaub so ntswg ntawm lub cev. Hauv cov leeg nqaij thiab lwm cov nqaij (muaj qhov tsis suav ntawm lub hlwb), Humalog® tsim kev thauj mus ntev ntawm cov kua nplaum thiab amino acids, nrawm nrawm anabolic cov txheej txheem thiab inhibits protein catabolism.Hauv daim siab, Humalog® nce qabzib ntxiv thiab zom cov piam thaj hauv daim ntawv ntawm glycogen, inhibits gluconeogenesis thiab ua kom nrawm hloov pauv ntawm cov piam thaj ntau hauv cov rog. Glucodynamic teb rau Humalog® yog ywj siab ntawm daim siab thiab lub raum tsis ua haujlwm. Cov chaw muag tshuaj ntawm Humalog® hauv cov menyuam yaus zoo ib yam rau cov laus.

Kev ntsuas rau siv

mob ntshav qab zib mellitus rau cov neeg laus thiab cov menyuam hnub nyoog tshaj li 3 xyoos, hauv kev kho tshuaj insulin kom pom tias muaj cov piam thaj hauv tsev

stabilization ntshav qab zib nyob rau hauv thawj theem

Tsuas tshuaj thiab tswj hwm

Cov koob tshuaj ntawm Humalog® yog txiav txim los ntawm tus kws kho mob nyob ntawm tus neeg mob lub sijhawm. Qhov rhiab ntawm cov neeg mob rau cov exulinous insulin yog qhov sib txawv, 1 ntu ntawm subcutaneously siv cov tshuaj insulin txhawb qhov nqus ntawm 2 txog 5 g ntawm cov piam thaj. Humalog® pom zoo kom noj tshuaj kom tsis txhob ua ntej 15 feeb ua ntej noj mov lossis sai sai tom qab noj mov 4-6 zaug hauv ib hnub (kho mob monotherapy) lossis 3 zaug hauv ib hnub nyob rau hauv kev sib xyaw nrog cov insulin ntev dua. Cov tshuaj raug cai yuav tsum nyob ntawm chav tsev sov.

Cov qauv ntawm kev tswj hwm ntawm Humalog® hauv cov neeg laus thiab cov menyuam yaus yog tus kheej! Ib koob tshuaj ib zaug thiab txhua hnub tau kho raws li cov txiaj ntsig ntawm kev tshawb fawb ntxiv txog cov piam thaj hauv cov ntshav thiab zis thaum nruab hnub thiab nyob ntawm seb tus neeg mob xav tau metabolic npaum li cas.

Qhov xav tau txhua hnub ntawm Humalog® yuav txawv, feem ntau 0.5-1.0 IU / kg / hnub.

Kev tswj hwm ntawm Humalog® cov tshuaj tiv thaiv kab mob yog ua raws li kev txhaj tshuaj rau niaj zaus. Kev tswj hwm kev mob ntawm Humalog® tuaj yeem ua kom tswj tau ntshav qabzib thaum ketoacidosis, mob hnyav, lossis thaum phais thiab tom qab lub sijhawm txiav. Hauv qhov no, nws yog ib qho tsim nyog feem ntau los tswj cov qib ntawm cov piam thaj hauv cov ntshav. Cov txheej txheem rau kev lis ntshav nrog kev ntsuas ntawm 0.1 IU / ml thiab mus txog 1 IU / ml ntawm Humalog® hauv 0.9% sodium chloride tov lossis 5% dextrose nyob ruaj khov rau chav sov li 48 teev.

Rau subcutaneous Txoj kev lis ntshav ntawm Humalog® nrog lub twj tso kua mis, cov lus qhia rau lub twj tso kua mis yuav tsum ua raws nraim. Txoj kev lis ntshav lub cev yog hloov pauv txhua 48 teev. Yog tias hypoglycemia txhim kho, Txoj kev lis ntshav yog txuas mus ntxiv. Thaum siv lub twj tso kua mis, Humalog® yuav tsum tsis txhob sib xyaw nrog lwm cov insulins.

Txhaj tshuaj subcutaneous yuav tsum tau muab rau lub xub pwg, lub duav, lub pob tw lossis lub plab. Qhov chaw txhaj tshuaj yuav tsum tau hloov chaw kom tib qhov chaw siv tsis ntau tshaj li ib hlis ib zaug. Nrog kev tswj hwm hypodermic ntawm Humalog®, kev saib xyuas yuav tsum tau saib xyuas kom tiv thaiv ib txoj hlab ntsha ntawm qhov nkag mus txhaj tshuaj. Tom qab kev txhaj tshuaj, qhov chaw txhaj tshuaj yuav tsum tsis txhob zaws tawm. Cov neeg mob yuav tsum tau kawm txog cov txheej txheem tseeb rau kev siv tshuaj insulin.

Humalog® cartridges tsis tas yuav rov ua haujlwm dua thiab tsuas yog siv tau yog tias lawv cov ntsiab lus yog cov kua ntshiab, tsis muaj kua, tsis muaj qhov pom pom.

Tsis txhob siv cov khoom yog tias nws muaj plaub ya ri. Cov cuab yeej ntawm lub lub laub txwv tsis pub sib xyaw lawv cov ntsiab lus nrog lwm cov tshuaj insulin amines ncaj qha rau hauv daim cartridge nws tus kheej. Daim cartridges tsis tsim los kom thim. Ua raws li cov khw muag cov lus qhia rau txhua tus neeg xaum xaum thaum tso daim ntawv rau hauv lub taub hau, txuas tus koob, thiab txhaj tshuaj insulin.

Xaiv qhov chaw txhaj tshuaj.

So cov tawv nqaij ntawm qhov chaw txhaj tshuaj nrog ib rab pas rwb pas nrig.

Tshem lub hau tiv thaiv sab nraud ntawm rab koob.

Kho cov tawv nqaij los ntawm rub nws los yog snapping nws mus rau qhov loj.

Ntxig rau rab koob thiab hno.

Tshem tawm rab koob thiab maj mam nias qhov chaw txhaj tshuaj rau ob peb feeb. Tsis txhob txhuam thaj chaw txhaj tshuaj.

Siv cov hau sab nraud ntawm rab koob, tam sim ntawd tom qab qhia cov tshuaj, tshem tawm rab koob thiab nrhiav nws hauv qhov chaw zoo.

Nws yog ib qho tsim nyog yuav tsum tau hloov chaw txhaj tshuaj nyob rau hauv xws li qhov chaw ntawd tsis siv ntau tshaj ib hlis ib zaug.

Tsis txhob sib xyaw cov tshuaj insulin hauv vials nrog cov tshuaj insulin hauv daim cartridges.

Cov kev phiv tshuaj uas tshwm sim ntau dua li ib rooj plaub yog teev raws li cov qib sau hauv qab no: ntau zaus (≥ 10%), feem ntau (≥ 1%, 0.1%, 0.01%, Koj tuaj yeem khaws cov suab thaj kom ruaj Txawm hais tias muaj mob hnyav autoimmune. Thiab ntau heev tshaj dua yog li, nrog cov mob hnyav hom 2 mob ntshav qab zib. Tsis tas yuav ua los ntxiv cov ntshav qabzib hauv koj lub cev txhawm rau kom raug tus kheej tiv thaiv ntshav qabzib ntshav qab zib. Saib cov vis dis aus uas tham txog qhov teeb meem no nrog leej txiv ntawm tus menyuam muaj ntshav qab zib hom 1. Kawm seb yuav ua li cas sib npaug ntawm cov khoom noj thiab cov tshuaj insulin.

Cev xeeb tub thiab pub niam misUltrashort insulin Humalog yog ntse siv los tswj ntshav qab zib thaum cev xeeb tub. Cov tshuaj no nyab xeeb rau poj niam thiab menyuam yaus, qhia tias xaiv tau raug tshuaj yog raug xaiv. Yuav tsum tau saib xyuas tshwj xeeb kom tsis txhob muaj ntshav nce siab ntau. Nyeem kab lus “thiab“ ”kom paub cov ntsiab lus.
Kev cuam tshuam nrog lwm yam tshuajQhov cuam tshuam ntawm cov tshuaj insulin yog me ntsis qaug zog los ntawm kev noj tshuaj txwv, thyroid hormone npaj, tshuaj tiv thaiv kab mob, thiazide diuretics, chlorprotixen, diazoxide, isoniazid, lithium, nicotinic acid, phenothiazine derivatives. Ua kom thoob plaws: beta-blockers, cawv, anabolic steroids, fenfluramine, guanethidine, tetracyclines, ntshav qab zib tshuaj, tshuaj aspirin, MAO inhibitors, ACE inhibitors, octreotide.


Noj ntau dhauQhov tshuaj tiv thaiv yog qhov muaj zog heev hom insulin. Txawm tias siv tshuaj ntau dhau me ntsis ntawm nws tuaj yeem txo cov ntshav qab zib ntau hauv cov menyuam yaus thiab cov neeg laus ntshav qab zib. Kawm paub txog cov tsos mob thiab kev kho mob ntawm cov teeb meem no. Yog tias muaj teeb meem tsis xis nyob hauv tus neeg mob, maj nrawm hu rau lub tsheb thauj neeg mob, thiab thaum nws taug kev, coj mus ntsuas tom tsev.
Daim ntawv tso tawmIb qho kev daws teeb meem rau subcutaneous thiab cov leeg tswj hwm muaj qhov siab ntawm 100 IU / 1 ml. 3 ml cartridges. Lawv tuaj yeem ntim rau hauv 5 daim los yog tsim rau hauv cov xaum xev uas siv pov tseg.
Cov lus thiab cov xwm txheej ntawm kev ciaTshuaj xyuas thiab mob siab rau ua tiav lawv. Cov tshuaj Humalog yuav muab khaws cia rau hauv tub yees kom ntev. Txee lub neej yog 2 xyoos. Kev siv yeeb tshuaj yuav tsum khaws cia hauv chav sov. Txee lub neej - tsis pub dhau 28 hnub.
Muaj pes tsawg leegCov tshuaj nquag: insulin lispro. Cov kev zam: glycerol, metacresol, zinc oxide, sodium hydrogen phosphate heptahydrate, hydrochloric acid daws 10% thiab / lossis sodium hydroxide tov 10%, dej rau kev txhaj tshuaj.

Koj cov piam thaj hauv ntshav yuav zoo dua yog tias koj hloov mus. Nws tsis ntxim rau cov neeg mob ntshav qab zib uas ua raws li cov khoom noj no kom suav cov carbohydrates hauv khob cij. Vim tias kev noj zaub mov zoo txhua hnub tsis pub tshaj 2.5 XE, thiab rau cov menyuam yaus txawm tsawg dua.

Raws li rau menyuam yaus, nws ua rau muaj kev hloov pauv hloov tus menyuam mob ntshav qab zib mus rau kev noj zaub mov kom tsawg, siv Actrapid lossis lwm qhov yeeb tshuaj luv dua li ntawm Humalog insulin, thiab kuj tsis kam siv lub tshuab nqus tshuaj insulin. Nyeem tsab xov xwm "" rau cov ntsiab lus ntxaws ntxiv.

Npaum li cas thiab ntau npaum li cas los ntaus nws?

Humalog sai dua li lwm cov tshuaj tuaj yeem kho cov ntshav qab zib kom ntshav khov. Yog li ntawd, nws yog qhov zoo tshaj kom muaj nws nrog koj thaum muaj xwm txheej. Txawm li cas los xij, qee tus neeg mob ntshav qab zib tau kam siv cov tshuaj insulin luv luv thiab ultrashort. Yog tias koj tswj hwm koj cov piam thaj hauv cov ntshav qis nrog kev noj zaub mov kom tsawg, koj tuaj yeem yuav los ntawm cov yeeb tshuaj luv luv.

Ntev npaum li cas txhaj tshuaj?

Txhua qhov txhaj ntawm cov tshuaj Humalog yuav siv li 4 teev. Tus mob ntshav qab zib uas ua raws li yuav tsum tau txhaj tshuaj insulin tsawg kawg. Nws feem ntau yuav tsum tau diluted kom raug txhaj ib koob uas tsawg dua 0.5-1 ib pawg. Tib neeg cov lus qhia tuaj yeem ua tsis tau tsuas yog rau cov menyuam yaus uas muaj ntshav qab zib hom 1, tab sis kuj yog rau cov neeg mob laus. Vim tias nws yog ib cov tshuaj uas muaj zog heev. Thaum siv cov tshuaj tsawg kawg, insulin nres ua haujlwm sai dua li teev hauv cov lus qhia ntawm nom tswv. Tej zaum qhov kev txhaj tshuaj yuav tas rau hauv 2.5-3 teev.

Tom qab txhaj txhua yam ntawm kev npaj ultrashort, ntsuas ntshav qab zib kom tsis muaj ntxov dua 3 teev tom qab. Vim tias txog lub sijhawm no, cov koob tshuaj insulin tsis muaj sijhawm tsis txaus los qhia nws cov nyhuv tag nrho. Raws li txoj cai, cov kabmob ntshav qab zib tau txhaj cov tshuaj insulin sai, noj, thiab tom qab ntawd ntsuas ntsuas qab zib ua ntej noj mov tom ntej. Tsuas yog nyob hauv cov xwm txheej uas tus neeg mob hnov. Hauv cov xwm txheej zoo li no, koj yuav tsum tau soj ntsuam tam sim ntawd txog qib piam thaj hauv cov ntshav thiab, yog tias tsim nyog, nqis tes ua.

Dab tsi yog qhov sib txawv ntawm Humalog thiab Humalog Mix?

Qhov nruab nrab tshuaj tiv thaiv Hagedorn (NPH), uas ua rau qeeb qis qis ntawm kev ua haujlwm ntawm insulin, tau ntxiv rau Humalog Mix 25 thiab 50. Cov insulin no sib txawv hauv cov ntsiab lus ntawm NPH. Cov khoom ntau dua, qhov ntau txuas ntxiv ua ntawm kev txhaj tshuaj. Cov tshuaj no tseem nrov vim tias lawv tuaj yeem txo cov naj npawb ntawm txhua hnub ntawm kev txhaj tshuaj, ua kom yooj yim rau kev tswj hwm ntawm kev siv tshuaj insulin. Txawm li cas los xij, lawv muab tsis tau kev tswj ntshav qab zib kom zoo. Yog li, lub vev xaib xaib tsis pom zoo siv lawv li.

Nyeem txog kev tiv thaiv thiab kev kho mob ntawm cov teeb meem:

Cov tshuaj insulin twg zoo dua: Humalog lossis NovoRapid?

Tej zaum yuav tsis muaj cov ntaub ntawv raug los teb cov lus nug no, uas feem ntau tau nug los ntawm cov neeg mob. Vim tias ntau hom insulin cuam tshuam rau txhua tus ntshav qab zib ib tus zuj zus. Zoo li Humalog, lawv muaj ntau tus kiv cua. Raws li txoj cai, cov neeg mob txhaj tshuaj uas lawv tau pub dawb.

Kev fab tshuaj yuam kom qee leej hloov los ntawm ib hom tshuaj insulin mus rau lwm tus. Peb rov hais dua, yog tias soj ntsuam sai li insulin ua ntej noj mov, nws yog qhov zoo dua los siv cov yeeb tshuaj luv luv, piv txwv li, dua li ntawm ultrashort Humalog, NovoRapid lossis Apidra. Yog tias koj xav xaiv qhov zoo tshaj plaws ntawm kev txuas ntxiv thiab ceev insulin, ces koj tsis tuaj yeem ua yam tsis muaj kev sim siab thiab qhov tsis raug.

Cov tshuaj ntxiv ntawm cov tshuaj insulin Humalog (lispro) - cov no yog cov tshuaj thiab. Cov qauv ntawm lawv cov lwg me me nws txawv, tab sis rau kev coj ua nws tsis txawv. thov tias Humalog ua nrawm dua thiab muaj zog dua nws cov neeg ua haujlwm. Txawm li cas los xij, tsis yog txhua tus neeg mob lees paub cov ntaub ntawv no. Ntawm cov ntawv sib tham ntawm Lavxias-hais txog tus mob ntshav qab zib, koj tuaj yeem nrhiav cov lus tsis txaus ntseeg.

Cov neeg mob uas muaj ntshav qab zib hom 1 thiab ntshav qab zib hom 2 uas tau soj ntsuam zoo yuav sim hloov cov tshuaj insulin lispro nrog cov tshuaj tiv thaiv luv luv. Piv txwv li, ntawm. Saum toj no nws tau sau hauv kev nthuav dav yog vim li cas qhov no tsim nyog ua. Ntxiv mus, luv luv insulin yog pheej yig dua. Vim tias nws tau nkag mus rau tom khw ntau xyoo dhau los.

Cia Koj Saib