Tsifran OD > Kev khomob thiab kev tiv thaiv

Tsifran OD muaj nyob rau hauv kev tsim ua ntev li ntawm cov ntsiav tshuaj, zaj duab xis-txheej: los ntawm yuav luag dawb dawb, dawb oval, ntawm daim nyias nyias zaj duab xis muaj cov ntawv sau hauv cov kua zaub dub "Cifran OD 500 mg" lossis "Cifran OD 1000 mg" (5 pcs. , hauv kab ntawv thawv los ntawm 1 lossis 2 lub hlwv).

1 ntsiav tshuaj muaj:

cov tshuaj nquag: ciprofloxacin - 500 mg lossis 1000 mg,
Cov khoom siv pabcuam: sodium bicarbonate, sodium alginate (Kelton LVCR), crospovidone (Kollidon CLM), hydroxypropyl methylcellulose, magnesium stearate, aerosil 200, talc,
lub plhaub muaj pes tsawg leeg: Opadry 31B58910 dawb (lactose monohydrate, hypromellose, macrogol 400, titanium dioxide), talc, hydroxypropyl methylcellulose, dej lim.

Cov Tshuaj Hauv Tshuaj

Tsifran OD yog cov tshuaj tua kab mob. Lub tshuab ntawm nws cov kev ua yog vim muaj cov kab mob bactericidal ntawm ciprofloxacin (fluoroquinolone), uas cuam tshuam kev ua ntawm topoisomerase II, tus kab mob enzyme tsim nyog rau kev rov ua haujlwm ntawm cov kab mob DNA (deoxyribonucleic acid). Qhov tsis muaj topoisomerase hauv cov txheej txheem biochemical ua rau muaj kev ua txhaum ntawm cov hluavtaws sib xyaw ua ke ntawm cov kab mob hauv cov kab mob.

Ciprofloxacin nquag tawm tsam txhua yam ntawm cov kab mob hauv qab no:

Gram-positive aerobic: Listeria monocytogenes, Bacillus anthracis, Enterococcus faecalis (kev sib raug zoo ntawm cov kab mob feem ntau), Streptococcus pyogenes, Staphylococcus epidermidis, Staphylococcus aureus (methicillin-rhiab thiab ua rau penicillococcus-tiv thaiv, tiv thaiv tsis tau, tiv thaiv tsis taus, tiv thaiv tsis taus, tiv thaiv tsis taus).
Gram-negative aerobic: Citrobacter diversus, Campylobacter jejuni, Citrobacter freundii, Escherichia coli, Enterobacter cloacae, Moraxella catarrhalis, Haemophilus parainfluenzae, Haemophilus influenzae, Klebsiella pneumoniae, Morganella gerogorererererer. , Shigella boydii, Shigella flexneri, Shigella dysenteriae, Shigella sonnei, Salmonella typhi.

Hauv cov tshuaj vitro, ciprofloxacin tsawg kawg ntawm cov tshuaj tiv thaiv tsis pub tshaj (MIC) ntawm 0.001 mg / ml yog nquag tawm tsam ntau dua 90% ntawm cov kab mob ntawm cov kab mob hauv qab no (cov tshuaj muaj txiaj ntsig ntawm qhov haujlwm no tsis tau hais meej):

aerobic gram-zoo: Staphylococcus haemophilus, Staphylococcus hominis,
Gram-negative aerobic: Edwardsiella tarda, Aeromonas hydrophila, Acinetobacter lwoffii, Brucella melitensis, Salmonella nkag>

Kev tawm tsam rau ciprofloxacin yog pom los ntawm: Burkholderia cepacia (feem ntau cov leeg), Stenotrophomonas maltophilia (qee hom), Bacteroides fragilis, Clostridium difficile thiab ntau lwm cov kab mob anaerobic.

Cov Tshuaj Pharmacokinetics

Tom qab kev tswj hwm ntawm qhov ncauj, qhov nqus ntawm ciprofloxacin los ntawm kev mob plab zom mov tshwm sim sai. Kev hnav ib ntus ntev tso tawm ntawm ciprofloxacin ua kom muaj kev saib xyuas ntawm nws qhov tsim nyog nyob rau hauv cov ntshav ntshav thaum noj Cifran OD 1 zaug hauv ib hnub.

Kev siab tshaj plaws (C_max) cov tshuaj muaj sia nyob hauv cov ntshav ntshav tau mus txog 6 teev thiab tuaj yeem kwv yees 0.0013 mg / ml tom qab siv ib zaug Cyfran OD 500 mg thiab 0.0024 mg / ml ntsiav tshuaj - Tsifran OD 1000 mg. Tag nrho cov ntshav plasma concentration (AUC) ntawm ciprofloxacin hauv qhov no sib raug kwv yees li 0.0083 thiab 0.0189 mg / ml / h.

Nrog cov ntshav plasma proteins khi 20-40%.

Ciprofloxacin yoojyim nkag mus rau hauv lub cev thiab cov nqaij. Nws muaj nyob hauv cov qaub ncaug, lub tso pa tawm ntawm cov qog ua kua ntawm lub qhov ntswg thiab bronchi, lymph, peritoneal fluid, phev, thiab lub tso pa ntawm caj pas prostate. Nws muab faib rau hauv lub ntsws, daim tawv nqaij, cov leeg, adipose, pob txha mos thiab pob txha pob txha, mob caj pas.

Hauv daim siab, ciprofloxacin yog qee cov metabolized.

T_1/2 (Ib nrab-lub neej) - 3.5-4.5 teev.

Li ntawm 50% ntawm cov tshuaj noj qhov ncauj yog tawm los ntawm ob lub raum tsis hloov, kwv yees li 15% hauv kev ua kom siv cov tshuaj metabolites. Kwv yees li ntawm 35% ntawm qhov koob tshuaj tau txais undergoes enterohepatic ncig.

Hauv kev mob raum uas tsis zoo thiab cov laus, T_1/2 tej zaum yuav raug txuas kom ntev, yog li ntawd, ntau dua kev noj tshuaj yuav tsum tau muab coj los kho rau hauv tus account creatinine tshem tawm (CC) ntawm tus neeg mob.

Nrog rau cov chav kawm nyob ruaj khov ntawm cov kab mob siab, cov tshuaj pharmacokinetics ntawm ciprofloxacin tsis hloov pauv ntau. Kev ceev faj yuav tsum tau siv rau hauv kev mob siab tsis zoo vim tias tsis muaj ntaub ntawv ntawm kinetics ntawm cov tshuaj nquag.

Kev ntsuas rau siv

Raws li cov lus qhia, Tsifran OD yog qhov qhia rau kev kho mob kis thiab kis mob los ntawm cov kab mob ua tau:

mob ntsws, exacerbation ntawm mob ntsws txhaws ntev, mob tshwm sim ntawm cystic fibrosis thiab lwm yam kev mob ntawm cov hlab ntsws qis ntawm kev kis tus kab mob sib kis,
mob sinusitis
cystitis, pyelonephritis (suav nrog cov ntawv nyuaj),
gonorrhea
kab mob ntev prostatitis,
cholecystitis, cholangitis, empyema ntawm lub zais plab, peritonitis, mob plab hauv plab thiab lwm yam kev mob plab hauv plab - hauv kev sib xyaw nrog metronidazole,
dermatological mob
mob hnyav thiab mob ntev ua rau osteomyelitis thiab lwm yam kev kis mob ntawm cov pob qij txha thiab pob txha,
anthrax,
zawv plab uas muaj mob kis (nrog rau "neeg mob raws plab"),
typhoid ua npaws.

Cov Yuav Tsum Muaj

mob raum tsis ua haujlwm (nrog CC tsawg dua 29 ml / min, suav nrog cov neeg mob ntawm hemodialysis),
mob plab pseudomembranous,
kho nrog tizanidine,
hnub nyoog txog 18 xyoo
cev xeeb tub lub sijhawm
pub niam mis
muaj tshuaj tiv thaiv kom haum rau cov tshuaj fluoroquinolone pawg,
kev tsis qaug rau lub zog ntawm cov tshuaj.

Nrog kev ceev faj, nws yog qhov yuav tsum tau los sau kev siv Tsifran OD hauv kev mob siab tsis ua haujlwm, lub raum tsis ua haujlwm nrog CC ntawm 35-50 ml / min, kev mob qog nqaij hlav, mob hlwb tsis zoo, mob hlwb, mob hlwb, mob vwm, mob puas thaum lub sijhawm kho mob yav dhau los nrog fluoroquinolones, hauv lub hnub nyoog laus.

Cov lus qhia rau kev siv Tsifran OD: txoj kev thiab qhov ntau npaum li cas

Cov tshuaj Cifran OD noj ntawm qhov ncauj, tom qab noj mov, nqos tag nrho (tsis rhuav tshem daim nyias nyias) thiab haus dej kom ntau.

Tus neeg mob yuav siv sij hawm noj tshuaj 1 zaug nyob rau ib hnub.

Pom zoo ntau npaum ntawm Tsifran OD:

cov kab mob sib kis thiab cov kab mob sib kis ntawm cov qis ntawm cov kab mob ua pa: mob hnyav thiab mob hnyav - 1 g rau 7-14 hnub, cov qauv mob hnyav thiab nyuaj - 1.5 g rau 7-14 hnub,
Mob ntsws mob sai: mob hnyav mus rau mob hnyav - 1 g rau 10 hnub,
mob txeeb zig: mob tsis txaus ntseeg daim ntawv - 0.5 g rau 3 hnub, mob hnyav thiab mob hnyav - 0.5 g rau 7-14 hnub, cov ntaub ntawv hnyav thiab tsis yooj yim - 1 g rau 7 –14 hnub
kab mob gonorrhea: mob tsis yooj yim rau daim ntawv - 0.5 g rau 1 hnub, nyuaj - 0.5 g rau 3-5 hnub,
tus kab mob ua rau mob prostatitis: mob me thiab mob hnyav - 1 g txhua, lub sijhawm ntev ntawm kev kho mob yog 28 hnub,
mob intraperitoneal (ua ke nrog metronidazole): cov ntawv nyuaj - 1 g rau 7-14 hnub,
kev kis kab mob ntawm daim tawv nqaij: mob hnyav thiab mob hnyav - 1 g rau 7-14 hnub, mob hnyav thiab nyuaj ntawm kev kis - 1.5 g, chav kawm ntawm kev kho mob - 7-14 hnub,
kis kab mob ntawm cov pob qij txha thiab pob txha: mob hnyav thiab mob hnyav - 1 g rau 28-42 hnub, cov ntawv hnyav thiab tsis yooj yim - 1.5 g rau 28-42 hnub lossis ntau dua,
zawv plab ntawm kev kis mob etiology: mob me, mob hnyav lossis hnyav - 1 g rau 5-7 hnub,
typhoid fever: mob hnyav, mob hnyav - 1 g rau 10 hnub,
anthrax (kev tiv thaiv thiab kev kho mob): 1 g txhua, lub sijhawm kawm - 60 hnub.

Kev lees txais ntawm cov tshuaj no yuav tsum txuas ntxiv mus yam tsawg 2 hnub tom qab kev ploj tag ntawm cov tsos mob ntawm tus kab mob.

Hauv lub raum tsis ua haujlwm, kev kho ntawm qhov tshuaj ntau npaum ntawm Tsifran OD tau nqa tawm mus rau hauv tus account tus neeg mob QC hauv cov hauv qab no:

QC saum toj no 50 ml / min: ib txwm koob,
KK 30–50 ml / feeb: 0.5–1 g ib hnub,
QC 5–29 ml / min, cov neeg mob ntawm lub hemodialysis lossis peritoneal lim ntshav: siv tsis pom zoo.

Rau cov txiv neej, QC tuaj yeem txiav txim siab los ntawm sib npaug ntawm tus neeg mob qhov hnyav (kg) los ntawm qhov sib txawv tau tom qab rho tawm ntawm 140 ntawm nws lub hnub nyoog hauv xyoo. Qhov tshwm sim tau muab faib los ntawm cov khoom - tus lej tau los ntawm sib npaug 72 los ntawm kev saib xyuas ntawm creatinine hauv cov ntshav ntshav (mg / dl).

Rau cov poj niam, QC sib raug rau qhov ntsuas taw qhia tau xam raws li phiaj xwm rau cov txiv neej, thiab sib ntxiv sib npaug los ntawm ib qho ntawm 0.85.

Hauv cov neeg mob laus, lub sij hawm teem ntawm fluoroquinolones yuav tsum ua rau suav txog qhov muaj hnub nyoog txog kev txo qis hauv lub raum kev ua haujlwm.

Sab sij huam

los ntawm cov kab mob hauv lub cev: photophobia, insomnia, txob taus, mob taub hau, kiv taub hau, nce nkees, mob plab, npau suav phem, ntxhov siab, tshee, tsis meej, peripheral tuag tes tuag taw (tsis hnov mob mob rhiab), kev nyuaj siab, ntau ntxiv intracranial siab, hallucinations, tsaus muag, tshwm sim kev xav tshwm sim hauv lub hlwb (suav nrog nrog kev ua rau tus kheej), mob hlwb txha caj qaum, mob taub hau,
los ntawm cov plab hnyuv siab tuaj ntawm lub cev: tsis hnov qhov hnov tsw thiab hnov qab, diplopia, hnov lus tsis zoo, tinnitus,
los ntawm cov txheej txheem hauv plab: mob plab, mob plab, xeev siab, ntuav, tsis nco qab, mob plab, mob siab, mob daj ntseg (feem ntau tiv thaiv keeb kwm yav dhau los ntawm kab mob siab), mob hepatonecrosis,
los ntawm cov hlab plawv: txo cov ntshav siab (BP), tachycardia, yaug ntsej muag, lub plawv dhia tsis xis,
los ntawm cov kab mob ntshav hematopoietic: leukopenia, granulocytopenia, eosinophilia, ua kom muaj ntshav liab, ntshav zais, mob ntshav txha ntshav, mob ntshav hlab plawv, mob ntshav qab zib, mob ntshav txhaws,
los ntawm cov kab mob tso zis: tso zis cia, hematuria, dysuria, polyuria, crystalluria (feem ntau tiv thaiv keeb kwm ntawm cov tshuaj tiv thaiv ntawm cov zis, tso zis tsawg), mob ntsig tsis ua haujlwm ntawm nephritis, albuminuria, glomerulonephritis, urethral los ntshav, lub raum tsis ua haujlwm, txo raum tsis ua haujlwm,
los ntawm kev tiv thaiv kab mob: tawv nqaij ua pob khaus, kub cev tshuaj, urticaria, petechiae, tawm ntsej muag (suav nrog los ntshav), cov tsos ntawm cov nodules me me ua rau pob, ua pa luv, o ntawm lub ntsej muag thiab / lossis larynx, erythema nodosum, vasculitis, erythema multiforme, tshuaj lom neeg muaj mob ua paug (Lyell's syndrome), mob siab rau mob erythema (Stevens-Johnson syndrome),
los ntawm cov leeg ua haujlwm: mob caj dab, mob raum tsis ntev, mob pob txha caj qaum, mob caj dab, leeg txhaws,
kev kuaj ntsuas: hypercreatininemia, hypoprothrombinemia, hyperglycemia, kev ua si ntau ntawm hepatic transaminases, hyperbilirubinemia, kev ua haujlwm ntawm lactate dehydrogenase thiab alkaline phosphatase,
lwm tus: qhov tsis muaj zog ntau, tawm hws ntau dhau, pseudomembranous colitis, candidiasis, photosensitivity.

Noj ntau dhau

Cov tsos mob: thim rov mob lom rau ob lub raum.

Kev Kho Mob: Tsis muaj ib qho tshuaj tua kab mob tshwj xeeb. Hauv qhov no, nws yog kev ceev nrawm los ntxias ntxias ua kom ntuav lossis yaug lub plab. Tom ntej yog kev teem sijhawm kho cov tsos mob, suav nrog infusions thiab lwm yam kev ntsuas rau kom muaj dej txaus, kho kev kho mob. Kev siv ntawm hemo- thiab peritoneal lim ntshav tsis muaj txiaj ntsig; nce txog li 10% ntawm kev lees txais qhov koob tshuaj ciprofloxacin tuaj yeem tshem tawm.

Cov lus qhia tshwj xeeb

Vim tias qhov kev pheej hmoo ntawm cov duab hluav taws xob tsis zoo cuam tshuam nrog kev siv fluoroquinolones, kev cuam tshuam ntau dhau los ntawm kev tiv thaiv hluav taws xob ultraviolet, suav nrog kev tshav ntuj ncaj qha, yuav tsum zam kom dhau lub sijhawm kho. Yog tias qhov kev tawm tsam qhov pom tshwm sim, cov ntsiav tshuaj yuav tsum txuas mus ntxiv.

Thaum kuaj pom qhov ua rau mob raws plab thiab ntev heev uas tau tshwm sim lub sijhawm lossis tom qab kho nrog Cifran OD, kev txhim kho ntawm kev muaj mob ua paug rau pseudomembranous yuav tsum tau txiav txim siab. Yog hais tias pseudomembranous mob plab yog paub tseeb, yuav tsum tau tshem tawm sai ntawm cov tshuaj thiab kev teem caij ntawm kev kho mob tsim nyog.

Txhawm rau tiv thaiv kev loj hlob ntawm crystalluria thaum lub sijhawm noj cov ntsiav tshuaj, nws yuav tsum haus cov kua txaus, tswj cov tshuaj tiv thaiv acidic thiab tiv thaiv kom tsis txhob muaj cov tshuaj ntau dua li niaj hnub noj.

Txij li thaum muaj keeb kwm ntawm cov organic puas rau lub hlwb, mob voos, mob vwm, lossis qaug dab peg, ciprofloxacin ua rau muaj kev txhim kho cov kev mob tshwm sim los ntawm cov leeg hlwb, cov neeg mob cov pathologies tuaj yeem kho Tsifran OD rau kev noj qab haus huv xwb.

Cov neeg mob yuav tsum tau qhia paub txog qhov yuav tsum tau txiav tawm cov tshuaj tam sim ntawd thaum muaj mob ntawm cov leeg thiab thawj cov tsos mob ntawm tus mob raosynovitis.

Dosage daim ntawv

Yeeb-tshuaj ntsiav tshuaj nrog kev txhawb nqa tso 500 mg thiab 1000 mg

Ib ntsiav tshuaj muaj

cov tshuaj heev - ciprofloxacin 500 mg thiab 1000 mg

intragranulate: sodium alginate, hypromellose, sodium bicarbonate, crospovidone, magnesium stearate,

extragranulate: magnesium stearate, huv talc, silicon dioxide colloidal anhydrous,

plhaubtab sis: Opadry 31V58910 dawb (hypromellose, lactose monohydrate, titanium dioxide (E171), macrogol 400, hypromellose, huv huv talc,

mem kuaOpacodeQha-1-17823 (Dub): lub ntsej muag zoo nkauj plhaw, isopropyl cawv, kua roj oxide / ferric oxide dub (E 172), butyl cawv, propylene glycol, 28% ammonia tov.

Cov ntsiav tshuaj zoo li dawb lub hau coated nrog zaj duab xis txheej los ntawm dawb mus rau yuav luag dawb, nrog cov ntawv sau "Cifran OD 500 MG" nyob rau hauv mem kua ntawm ib sab. Ntev 17.1  0.1 hli, dav 8.1  0.1 hli, tuab 5.6  0.3 hli (rau qhov ntau npaum li 500 mg).

Cov ntsiav tshuaj zoo li dawb kheej kheej, coated nrog zaj duab xis txheej los ntawm dawb mus rau yuav luag dawb, nrog cov ntawv sau "Cifran OD 1000 MG" nyob rau hauv mem kua ntawm ib sab. Ntev 21.2  0.1 hli, qhov dav 10.6  0.1 hli, tuab 7.6  0.3 hli (rau qhov muab ntau npaum li 1000 mg).

Yeeb tshuaj sib cuam tshuam

Nrog tib lub sijhawm siv Tsifran OD:

metronidazole, beta-lactams, clindamycin, aminoglycosides thiab lwm yam tshuaj tua kab mob: ua rau mob synergism. Rau kev kho mob kom zoo rau kev mob kis los ntawm Pseudomonas tshwj xeeb, kev sib xyaw nrog ceftazidime thiab azlocillin, kab mob streptococcal nrog cov tshuaj tua kab mob beta-lactam (meslocillin, azlocillin), staphylococcal kab mob nrog vancomycin, isoxazolpenicillin kab mob, anaerobic aminerocytamines, anaerob
theophylline: ua rau kom nws cov siab xav hauv ntshav ntshav,
tizanidine: Ua rau muaj kev pheej hmoo ntawm cov lus txo hauv cov ntshav siab, cov tsos ntawm kev nkees,
cov tshuaj tiv thaiv kab mob thiab tshuaj thaiv kab mob: txo qhov nqus ntawm Cyfran OD thaum noj qhov ncauj,
didanosine: pab txo qhov nqus ntawm ciprofloxacin,
cov tshuaj tiv thaiv kab mob uas suav nrog aluminium lossis magnesium hydroxide nyob rau hauv muaj pes tsawg leeg: pab txhawb kom txo qis hauv kev nqus ntawm ciprofloxacin, yog li no kev sib xyaw no yog contraindicated,
tshuaj uas thaiv cov tubular tso pa tawm, suav nrog probenecid: txo qis raum tsis ua haujlwm ntawm ciprofloxacin,
analgesics: ua rau muaj kev cuam tshuam ntau ntxiv los ntawm ciprofloxacin los ntawm lub hauv nruab siab,
phenytoin: yuav txo qis lossis nce koj cov ntshav plasma concentration,
sucralfate: txo qhov nqus ntawm Cyfran OD,
antagonists ntawm H₂- histamine receptors: tsis muaj kev cuam tshuam loj hauv kev kho mob rau lub bioavailability ntawm ciprofloxacin,
qhov ncauj anticoagulants, suav nrog warfarin thiab nws cov lus qhia: txhim kho lawv cov txiaj ntsig, yog li ntawd, thaum ua ke nrog cov tshuaj, kev tshawb fawb tsis tu ncua ntawm cov ntshav coagulation system yuav tsum,
glyburide: tuaj yeem ua rau mob ntshav qab zib siab heev,
qhov ncauj hypoglycemic tus neeg sawv cev, caffeine thiab lwm yam xanthines: nce lawv cov qib siab thiab lengthen T_1/2,
metoclopramide: nrawm nws qhov nqus,
uricosuric cov neeg sawv cev: yuav luag 50% ua rau qeeb ntawm kev tshem tawm ciprofloxacin, ua rau muaj kev nce ntxiv hauv nws cov ntshav siab,
cyclosporine: txhim kho nws cov nyhuv nephrotoxic. Txij li thaum muaj kev nce qib hauv cov ntshiab creatinine, nws qib yuav tsum raug tswj 2 zaug hauv ib lim tiam.

Cov qauv ntawm Cifran OD yog: Cifran, Ciprofloxacin, Vero-Ciprofloxacin, Ifippro, Quintor, Basigen, Betaciprol, Nircip, Procipro, Ciprinol, Ciprobay, Ciprolaker, Cipromed, Ciprofloxabol, Ciploxinal, Ciproxx.

Cov chaw muag tshuaj

Ciprofloxacin pab txhawb cov ntsiav tshuaj tso tawm yog tsim los tso tawm cov tshuaj ntawm tus nqi qis dua piv rau cov ntsiav tshuaj tawm sai.

Cov ntaub ntawv pharmacokinetic ntawm ciprofloxacin pab txhawb-tso cov ntsiav tshuaj 1000 mg ib hnub ib zaug yog piv nrog cov ntaub ntawv ntawm 500 mg ciprofloxacin ntsiav tshuaj nrog kev tso tawm ceev ib hnub ob zaug, nyob rau hauv cov nqe lus ntawm kev sib piv AUC tshaj li 24 teev ib koob tshuaj.

Tom qab kev tswj hwm ntawm qhov ncauj, ciprofloxacin yog nqus nrawm feem ntau yog ua rau txoj hnyuv me. Qhov siab tshaj plaws ntawm ciprofloxacin hauv cov dej ntshiab yog ua tiav tom qab 1-2 teev. Bioavailability yog li 70-80%. Cov txiaj ntsig ntawm qhov kev xav ntau tshaj plaws hauv ntshav (Cmax) thiab thaj chaw hauv qab nkhaus "concentration - sijhawm" (AUC) nce siab hauv qhov sib piv rau cov koob tshuaj.

Kev sib txuas ntawm ciprofloxacin nrog plasma proteins yog 20-30%, cov tshuaj nquag muaj nyob rau hauv cov ntshav ntshav feem ntau hauv cov ntawv tsis-ionized. Ciprofloxacin yog faib dawb hauv cov nqaij thiab dej hauv lub cev. Qhov ntim ntawm kev faib tawm hauv lub cev yog 2-3 l / kg. Qhov kev tso siab ntawm ciprofloxacin hauv cov ntaub so ntswg yog ntau dua li cov siab nyob hauv cov ntshav cov ntshav.

Biotransformed hauv lub siab. Plaub ciprofloxacin metabolites nyob rau hauv kev muaj peev xwm me me tuaj yeem tshawb pom hauv cov ntshav: diethylcycrofloxacin (Ml), sulfociprofloxacin (M2), oxociprofloxacin (MZ), formylcycrofloxacin (M4), peb ntawm cov (M1-MZ) qhia cov tshuaj tiv thaiv kev ua haujlwm ntawm cov dej num hauv cov tshuaj tiv thaiv kab mob kua qaub. Cov tshuaj tiv thaiv kab mob ua si nyob rau hauv vitro ntawm M4 metabolite, uas yog tam sim no cov nyiaj tsawg dua, zoo ib yam nrog cov kev ua ntawm norfloxacin.

Ciprofloxacin raug cais tawm feem ntau los ntawm lub raum los ntawm kev pom cov txhaws thiab lub raj rau txoj hlab ntshav, ib qho me me los ntawm kev mob plab. Kev tso zis tawm hauv lub sijhawm 24 teev tom qab siv tshuaj. Los ntawm 1 mus rau 2% ntawm cov koob tshuaj tau noj yog tawm hauv daim ntawv ntawm metabolites nrog cov kua tsib, li 20-35% ntawm cov tshuaj tau tawm hauv cov quav hauv 5 hnub tom qab kev tswj hwm. Ntshav dej ib nrab-lub neej nyob rau hauv cov neeg mob uas lub raum kev ua haujlwm yog kwv yees li 7 teev.

Pharmacokinetic tshuaj ntsuam ntawm cov tshuaj tawm ntawm lub qhov ncauj tam sim (ib koob) thiab ciprofloxacin cov ntaub ntawv rau kev tswj hwm tshuaj (ib qho thiab ntau koob) qhia tias plasma ntau ntau ntawm ciprofloxacin ntau dua rau cov neeg laus (tshaj 65) piv nrog cov neeg hluas. Cmax nce li ntawm 16% mus rau 40%, thiab nruab nrab AUC nce txog li 30%, uas tsawg kawg yog qee qhov vim kev txo qis hauv lub raum hauv cov neeg laus. Ib nrab-lub neej tsuas yog siv sijhawm me ntsis rau cov laus (

20%). Cov kev sib txawv no tsis yog qhov tseem ceeb hauv tsev kho mob.

Hauv cov neeg mob uas lub raum tsis ua haujlwm, lub sijhawm ib nrab ntawm ciprofloxacin yuav txuas ntxiv. Kev txhaj tshuaj tsis tsim nyog rau cov neeg mob uas tsis tuaj yeem tiv thaiv tus kab mob tso zis tau txais 500 mg ntawm kev tso tawm ciprofloxacin ntau npaum li cas daim ntawv tshuaj. Rau cov mob nyuaj tso zis thiab mob tsis yooj yim xws li pyelonephritis, qhov twg ib koob ntawm 1000 mg siv, kev noj tshuaj ntawm ciprofloxacin nrog qhov ua ntev yuav tsum txo qis rau 500 mg ib hnub ib zaug (creatinine tshem tawm hauv qab 30 ml / min).

Hauv kev kawm ntawm cov neeg mob uas muaj lub qog mob ntshav siab ruaj khov ntawm daim siab, tsis muaj qhov hloov pauv ntau hauv cov chaw muag tshuaj ntawm ciprofloxacin. Nyob rau tib lub sijhawm, kinetics ntawm ciprofloxacin hauv cov neeg mob uas muaj lub siab tsis ua haujlwm yog paub tsis txaus.

Ciprofloxacin yog cov tshuaj siv hluavtaws ntau los ntawm cov tshuaj fluoroquinolones.

Ciprofloxacin muaj nyob rau hauv cov dej num hauv vitro tiv thaiv ntau cov kab mob gram-negative thiab gram-zoo. Cov kab mob ua haujlwm ntawm ciprofloxacin yog ua los ntawm inhibiting hom II cov kab mob topoisomerases (topoisomerase II (DNA gyrase) thiab topoisomerase IV), uas tsim nyog rau kev rov ua dua, hloov pauv, kho thiab rov ua kom zoo ntawm cov kab mob DNA.

Hauv tshuaj tiv thaiv vitro tiv thaiv rau ciprofloxacin feem ntau tshwm sim los ntawm kev sib kis ntawm cov kab mob topoisomerases thiab DNA gyrase thiab kev loj hlob maj mam dhau los ntawm kev hloov pauv ntawm multistage.

Kev hloov pauv ib leeg tuaj yeem ua rau txo qis rhiab ntau dua li kev tsim kho cov kev tiv thaiv kev kho mob, txawm li cas los xij, ntau kev sib hloov tseem ceeb ua rau kev txhim kho cov chaw kuaj mob tseem ceeb rau ciprofloxacin thiab hla kev tiv thaiv cov tshuaj quinolone. Kev tawm tsam ciprofloxacin, zoo li ntau lwm yam tshuaj tua kab mob, tuaj yeem tsim los ntawm qhov txo qis permeability ntawm cov kab mob ntawm cov xov tooj ntawm phab ntsa (raws li feem ntau yog Pseudomonas aeruginosa) thiab / lossis kev ua haujlwm ntawm kev nthuav tawm los ntawm microbial cell (efflux). Kev txhim kho ntawm kev tsis kam tiv thaiv vim yog coding Qnr gene hauv ib cheeb tsam ntawm plasmids tau tshaj tawm. Cov txheej txheem los tiv thaiv uas ua rau cov tsis muaj zog ntawm penicillins, cephalosporins, amino glycosides, macrolides, thiab tetracyclines tej zaum tsis cuam tshuam nrog cov tshuaj tua kabmob ntawm ciprofloxacin. Cov kab mob me tiv taus cov tshuaj no tej zaum yuav nkag siab zoo rau ciprofloxacin. Kev siv tshuaj tua kab mob tsawg kawg nkaus (MBC) feem ntau tsis tshaj qhov qis tshaj plaws inhibitory concentration (MIC) ntau dua 2 zaug.

Hla tsis kam. Tsis pom tus kab mob sib kis ntawm ciprofloxacin thiab cov tshuaj tua kab mob ntawm lwm cov chav kawm.

Ciprofloxacin nquag tawm tsam ntau feem ntau ntawm cov kab mob hauv qab no uas yog hauv cov xwm txheej hauv vitro, thiab hauv kev kho mob kev kho mob ntawm kev kho mob.

Aerobic Gram-Zoo Cov kab mob sib kis : Bacillus anthracis, Staphylococcus aureus (methicillin-rhiab) Staphylococcus saprophyticus, Streptococcus spp.Aerobic gram-cov kab mob tsis zoo : Aeromonas spp., Moraxella catarrhalis, Brucella spp., Neisseria meningitidis, Citrobacter koseri, Pasteurella spp., Francisella tularensi, Salmonella spp., Haemophilus ducreyi, Shigella spp., Haemophilius influenzae, Vibri.Cov kab mob Anaerobic : Mobiluncus spp .

Lwm yam kab mob me : Chlamydia trachomatis, Chlamydia mob ntsws, Mycoplasma hominis, Mycoplasma pneumoniae. Ib qho txawv ntawm kev nkag siab zoo rau ciprofloxacin tau pom tias muaj cov kab mob hauv qab no: Acinetobacter baumann, Burkholderia cepacia, Campylobacter spp., Citrobacter freundii, Enterococcus faecalis, Enterobacter aerogenes, Enterobacter cloacae, Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Morganeria ganorerroman morana gomororrinos. Pseudomonas fluorescens, Serratia marcescens, Streptococcus pneumoniae, Peptostreptococcus spp., Propionibacterium acnes. Nws ntseeg tias ciprofloxacin muaj peev xwm tiv taus ntuj. Dab Tsi Staphylococcus aureus (methicillin-resistant) Stenotrophomonas maltophilia, Actinomyces spp., Enteroccus faecium, Listeria monocytogenes, Mycoplasma genitalium, Ureaplasma urealitycum, anaerobic microorganisms (tshwj tsis yog Mobiluncus spp., Peptostreptococus spp., Mob (Propionibacterium acnes) .

Kev txheeb xyuas txog Tsifran OD

Kev tshuaj xyuas ntawm Tsifran OD yog qhov zoo, lawv qhia tias muaj kev ua haujlwm ntau los ntawm cov tshuaj hauv kev kho mob ntau yam kab mob.

Cov neeg mob qhia tias muaj kev mob siab rau ncaj ncees ntawm Cifran OD, tsis muaj cov kev mob tshwm sim los ntawm txoj kev mob tshwm sim sai sai, qhov pib sai ntawm kev kho nrog mob hnyav.

Tsuas tshuaj thiab tswj hwm

Cov ntsiav tshuaj yuav tsum tau nqos yam tsis muaj ntxo, ntxuav nrog dej. Lawv tuaj yeem noj tsis hais lub sijhawm noj mov. Thaum noj rau ntawm lub plab tas, cov tshuaj nquag yuav nqus sai dua.

Cifran OD ntsiav tshuaj noj ib hnub ib zaug.

Qhov ntau npaum li cas thiab cov chav kawm ntawm kev kho yog nyob ntawm qhov ntsuas, qhov hnyav thiab hauv zos ntawm kev kis tus kab mob, kev cuam tshuam ntawm cov kab mob pathogenic rau cov ciprofloxacin, lub raum muaj nuj nqi ntawm cov neeg mob, thiab ntawm kev soj ntsuam thiab bacteriological zoo.

Txog kev kho qee yam kab mob (piv txwv li Pseudomonas aeruginosa, Acinetobacter lossis Staphylococci) tej zaum yuav tsum tau txhaj ntau dua ntawm ciprofloxacin thiab kev tswj hwm nrog lwm cov tshuaj tiv thaiv zoo.

Txog kev kho qee yam mob (piv txwv li cov kab mob ntawm lub plab mob hauv plab, mob plab, mob hauv cov neeg mob neutropenic, thiab kab mob ntawm cov pob txha thiab pob qij txha), kev koom tes nrog lwm cov kab mob antibacterial uas tsim nyog yuav tsim nyog nyob ntawm cov kab mob koom nrog.

Lub sijhawm kho (feem ntau suav nrog kev pib kho mob nrog kho nrog ciprofloxacin)

Cov kab mob ua pa qis dua

Sab saud mob ntsws

Exacerbation ntawm kev mob caj dab ntev

1000 mg - 1500 mg

Ntev li mob otitis media

1000 mg - 1500 mg

Malignant otitis sab nraud

28 hnub txog 3 hlis

Mob txeeb zig

500 mg - 1000 mg

Rau cov poj niam ntawm lub hnub nyoog premenopausal, 500 mg (ib koob tshuaj)

Mob cystitis, mob tsis yooj yim rau pyelonephritis

1000 mg -1500 mg

tsawg kawg 10 hnub, yuav nyob ntev dua 21 hnub rau qee kis mob hnyav (piv txwv li ua tsis tau)

2 txog 4 lub lis piam (mob) 4 txog 6 lub lis piam (mob)

Chaw mos ua paug

Gonococcal mob rau txoj hlab zis thiab lub ncauj tsev menyuam

500 mg (ib koob tshuaj xwb)

1 hnub (ib koob tshuaj xwb)

Orchoepididymitis thiab mob txha caj qaum ntawm cov plab hnyuv siab raum

1000 mg -1500 mg

yam tsawg kawg 14 hnub

Mob plab hnyuv thiab mob rau sab hauv plab

Zawv plab los ntawm cov kab mob pathogens, incl. Ntxaug Yaj spp., tsuas yog hom 1 Shigella dysenteriae thiab qhov kev kho mob ntawm cov neeg taug kev mob raws plab heev

Hom 1 mob raws plab Shigella dysenteriae

Hnub tas sij hawm:

Cov sijhawm so:
Tso tshuaj los ntawm cov tshuaj.

Daim Ntawv Tso Npe Sau Npe
Ranbaxy Laboratories Limited / Ranbaxy Laboratories Txwv
Sahibzada Ajit Singh Nagar (Mohali) - 160055, (Punjab), Is Nrias teb / Sahibzada
Ajit Singh Nagar (Mohali) - 160055, (Punjub), Is Nrias teb
Kev thov cov neeg tau txais kev pabcuam yuav tsum muab xa mus rau qhov chaw sawv cev ntawm lub tuam txhab
Lub Chaw Ntsuas Hluav Taws Xob Chaw Nyob ntawm chaw nyob: 129223, Moscow, Prospect Mira, Chaw Lavxias Lavxias Txhua Chaw Tso Khoom, Chaw Ua Lag Luam Technopark, tsim tsev 537/4, chaw haujlwm 45-48.

Chaw tsim tshuaj paus
Ranbaxi Laboratories Limited, Paonta Sahib, Dist. Sirmur 173025, Himachal Pradesh, Is Nrias teb.
Ranbaxy Laboratories Limited, Paonta Sahib, Dist. Sirmour 173025, Himachal Pradesh, Is Nrias teb.

Dab Tsi yog Tsifran ST

Raws li kev faib cov tshuaj thiab pharmacological, Tsifran ST yog pawg ntawm cov tshuaj tua kabmob (tshuaj tua kab mob) los ntawm chav kawm ntawm fluoroquinolones. Cov tshuaj hauv cov ntsiav tshuaj hom yog tsim los ntawm lub tuam txhab Indian. Kev xaiv CT ntawm Cyfran 250 mg thiab 500 mg yog muaj. Lawv muag hauv cov thawv ntawv thawv, cov ntsiav tshuaj yog nyob rau hauv cov hlwv ntsej muag ua los ntawm txhuas ntawv nyiaj, cov lus qhia rau kev siv yog qhov tsim nyog ntxiv. Cov ntsiav tshuaj yog oval, daj hauv cov xim, zaj duab xis-txheej.

Yam khoom muaj sia

Cifran ST muaj ob yam khoom xyaw - 250 lossis 500 mg ntawm ciprofloxacin hydrochloride thiab 300 lossis 600 mg ntawm tinidazole. Cov kev zam yog microcrystalline cellulose, colloidal anhydrous silicon magnesium stearate, sodium starch glycolate, sodium lauryl sulfate. Cov khaubncaws sab nraud povtseg ntawm cov ntsiav tshuaj muaj sodium hmoov txhuv nplej siab glycolate, purified talc, sodium lauryl sulfate, microcrystalline cellulose, colloidal anhydrous silicon, thiab magnesium stearate. Lub plhaub muaj cov dej lim dej, opadra daj.

Ciprofloxacin

Txhawm rau txwv cov enzymes uas tsim nyog rau kev loj hlob ntawm cov kab mob, ciprofloxacin yog ntxiv rau cov tshuaj tua kabmob ua kom muaj kabmob ST Cifran. Nws inhibits cov metabolism hauv ib txwm ntawm cov neeg sawv cev ntawm tus kab mob, muaj cov kab mob bactericidal ntawm cov hlwb hauv cov theem so. Cov tshuaj yog nkag siab rau cov kab mob gram-tsis zoo thiab cov kab mob gram-zoo - cov no yog cov kab mob enterobacteria, morganella, chlamydia. Ciprofloxacin nkag mus rau hauv lub cell, inhibits cov kab mob me me uas tsim cov beta-lactamases.

Qhov tsim kho ntawm nitroimidazole yog ib feem ntawm Cyphran ST, uas ua tawm tsam anaerobes thiab protozoa. Tinidazole ua tau zoo, nkag mus rau cov hlwb, ua rau DNA ntawm cov kab mob lossis tiv thaiv nws cov synthesis. Nws rhuav tshem cov kab mob clostridia, peptococci, gardnerella, kab mob fusobacteria thiab lwm yam kev sib kis mob feem ntau. Kev siv cov tinidazole yog ua haujlwm tawm tsam qhov yooj yim thiab feem ntau ua rau anaerobes.

Los ntawm cov ntsiav tshuaj twg Tsifran ST

Ib pob ntawm cov ntsiav tshuaj muaj 10 lossis 100 daim nrog cov lus qhia rau kev siv. Cov kabmob dabtsi Tsifran ST siv rau:

mob ntsws ntev
lub ntsws ua qias neeg
empyema
osteomyelitis mob,
zawv plab
siab tawm
periodontitis, mob periostitis, lwm yam kab mob hniav ntawm qhov ncauj kab noj hniav,
Ciprofloxacin tuaj yeem kho kho mob raws plab, amoebic los yog sib xyaw plab tsis haum.

Mechanism ntawm kev ua

Kev npaj tshuaj tua kab mob Tsifran nrog kev sib xyaw ua ke yog npaj rau kev kho mob sib xyaw ua ke los ntawm kev mob hlwb thiab aerobes, kis kab mob ntawm txoj hnyuv plab. Kev sib xyaw ntawm tinidazole thiab ciprofloxacin cuam tshuam rau ob hom kab mob me, muab cov tshuaj tua kab mob nrog cov kev ua kom dav. Ob qhov tshuaj yeeb dej cawv tau zoo nyob rau hauv txoj hnyuv, mus txog qhov siab kawg nyob rau hauv ob peb teev.

Lub bioavailability ntawm tinidazole yog 100%, ntshav protein khi yog 12%. Cov tshuaj sib xyaw ua ke sai sai rau hauv cov ntaub so ntswg, nce mus rau qhov chaw siab. Tinidazole pom nyob rau hauv cov kua dej ua kom siav, cov tshuaj tawm hauv cov zis thiab quav. Ciprofloxacin yog nqus tom qab siv, nws txoj kev noj qab haus huv yog 70%. Lwm 30% khi rau cov protein nyob hauv plasma concentration. Cov tshuaj nkag rau hauv lub ntsws, daim tawv nqaij, rog, cov leeg, pob txha mos, pob txha.

Tsifran ST tshuaj tua kab mob - cov lus qhia rau kev siv

Cov tshuaj ua kom sib xyaw ua ke yog muag hauv cov chaw muag tshuaj, khaws cia hauv qhov kub txog 25 degrees hauv qhov chaw huv, huv, tsis muaj me nyuam yaus. Txee lub neej yog 2 xyoos. Cov lus qhia siv ST Tsifran muaj cov lus qhia tshwj xeeb:

tsis txhob muab tshuaj rau cov neeg mob qis dua 12 xyoos,
tsis siv tom qab hnub tas sij hawm,
thaum ua ke nrog kev tiv thaiv tsis ncaj rau lub cev muaj peev xwm txhim kho lawv cov hauj lwm zoo thiab kev ua ntawm ethanol,
sib xyaw nrog sulfonamides, tshuaj tua kab mob, tab sis tsis sib haum nrog ethionamide,
thaum ua ke nrog phenobarbital accelerates metabolism hauv,
kev siv sib xyaw ua ke ua rau kom muaj siab dua ntawm theophylline, kev sib xyaw ua ke, txo cov txheej txheem prothrombin,
Cifran nrog cov lus sau ua ntej ST ua rau lub zog lom ntawm cyclosporin, nce ntshiab cov creatinine,
tib lub sij hawm siv nrog cov tshuaj uas tsis yog tshuaj steroidal ua rau muaj kev pheej hmoo ntawm qaug dab peg,
thaum noj cov ntsiav tshuaj, tsis txhob siv lub hnub ntev dhau los kom tsis txhob muaj kev cuam tshuam ntawm phototoxicity,
tsis txuam nrog haus dej cawv - muaj mob, mob plab, xeev siab, ntuav,
cuam tshuam qhov ceev ntawm qhov tshuaj tiv thaiv, yog li ntawd nws yog txwv tsis pub thaum tsav tsheb, ua haujlwm txaus ntshai,
kev siv tshuaj kho mob rau kev noj qab haus huv yog tsim rau cov neeg mob vwm, kev huam ywb, mob ntshav vog thiab mob hlwb, mob hlab ntsha hlwb,
kev noj tshuaj yog nres yog tias muaj mob thoj plab heev, mob leeg, cov tsos mob tendovaginitis,
thaum lub sij hawm kho cov tshuaj tua kab mob, cov kws kho mob soj ntsuam cov xwm txheej ntawm cov ntshav peripheral suav.

Tso cov ntaub ntawv thiab cov nyob ua ke

Cov tshuaj yog muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj. Lawv yog them nrog zaj duab xis daim nyias nyias, muaj oval duab thiab dawb xim.

Cov tshuaj muaj 1000 mg ntawm cov tshuaj nquag, uas yog siv ciprofloxacin. Qhov kev npaj muaj cov ntu pabcuam:

crospovidone
shellac
hypromellose,
talcum hmoov
isopropanol
oxide dub hlau
silica
ammonia aqueous
sodium bicarbonate,
sodium alginate
propylene glycol
magnesium stearate.

Cov tshuaj yog muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj. Lawv yog them nrog zaj duab xis daim nyias nyias, muaj oval duab thiab dawb xim.

Pharmacological kev txiav txim

Cuab yeej muaj cov nyhuv bactericidal. Cov tshuaj siv tau zoo tsis yog tawm tsam kev tawm tsam kab mob, tab sis kuj muaj ntau yam kab mob ntawm cov kab mob uas nyob hauv lub xeev zoo.

Tsifran yog qhov tsim nyog rau kev tshem tawm cov kab mob tshwm sim los ntawm kev ua ub no ntawm gram-negative thiab gram-positive microflora.

Dab tsi pab

Cov cuab yeej pab tua cov kab mob hauv qab no:

mob sinusitis
zis mob (cystitis),
hom mob raws plab,
mob peritonitis
cov txheej txheem mob hauv zos hauv lub zais khoom,
kev puas tsuaj rau lub raum hlab (pyelonephritis),
exacerbation ntawm mob ntsws ntev,
ntev kab mob prostatitis
o ntawm lub bile ducts,
gonorrhea
mob ntsws
typhoid ua npaws
pathologies ntawm cov pob txha thiab pob qij txha, suav nrog mob txha thiab mob txha,
kis kab mob ntawm daim tawv nqaij.

Tsifran OD tso cai rau koj tuaj yeem kho mob ntawm lub zais zis (cystitis).

Nrog saib xyuas

Nws yog ib qho tsim nyog yuav tsum them sai sai rau cov teeb meem hauv qab no thiab pathologies:

daim siab ua hauj lwm
cerebral arteriosclerosis thiab teeb meem nrog cov ntshav mus rau lub nruab nrog cev,
leeg mob puas yog los ntawm txoj kev kho siv cov tshuaj fluoroquinolone,
kev nyuaj siab mob hlwb
qaug dab peg
lub siab ua tsis taus haujlwm,
lub raum tsis ua hauj lwm.

Hauv cov rooj plaub no, cov tshuaj tau sau tseg nrog ceev faj.

Yuav noj li cas Cifran OD

Cov tshuaj yog siv 1 zaug nyob rau ib hnub, i.e. txhua 24 teev.

Cov tshuaj yuav tsum tau noj ntawm qhov ncauj, ntxuav lub ntsiav tshuaj nrog ib khob dej huv.

Cov tshuaj yuav tsum tau noj ntawm qhov ncauj, ntxuav lub ntsiav tshuaj nrog ib khob dej huv. Tus kws kho mob koom nrog kev noj tshuaj, vim tias thaum sau tshuaj, ib qho yuav tsum coj mus rau hauv lub hnub nyoog, qhov mob ntawm tus neeg mob thiab theem ntawm kev txhim kho pathology.

Lub sijhawm kho yog xaiv rau hauv kev txiav txim siab mob hnyav ntawm tus kabmob. Nws yuav tsum nco ntsoov tias cov chav kawm ntawm kev kho mob yuav tsum txuas ntxiv rau 2 hnub ntxiv tom qab ploj ntawm cov tsos mob.

Noj cov tshuaj rau ntshav qab zib

Thaum lub sij hawm tsim kho cov ntshav qab zib mellitus, cov tshuaj siv tau raws li cov lus qhia. Ua ntej koj pib noj cov tshuaj, koj yuav tsum sab laj nrog tus kws tshaj lij.

Thaum lub sij hawm tsim kho cov ntshav qab zib mellitus, cov tshuaj siv tau raws li cov lus qhia.

Lub plab zom mov

Los ntawm cov hnyuv zom, cov tsos mob hauv qab no yuav tshwm sim:

cholestatic mob daj ntseg
daim siab mob hlwb necrosis,
poob phaus
zawv plab
flatulence
kab mob siab
mob hauv plab
ntuav thiab xeev siab.

Ntawm ib feem ntawm cov hnyuv plab, cov kev mob tshwm sim tuaj yeem pom los ntawm ntuav thiab yaum kom xeev siab.

Hematopoietic plab hnyuv siab raum

Cov kev mob tshwm sim tom qab no tuaj yeem tshwm sim los ntawm cov kabmob hemopoietic:

hemolytic yam anemia,
nce platelet suav hauv cov ntshav,
nce ntshav dawb ntawm tes suav,
platelet suav txo,
granulocytopenia,
leukopenia
hloov pauv tus naj npawb ntawm eosinophils.

Nruab nrab hauv lub paj hlwb

Cov tsos mob hauv qab no tshwm sim:

mob taub hau, suav nrog migraine,
tsaus muag
ntshai ntawm lub teeb
tshee hnyo
kev xav ntawm kev ntxhov siab
txob taus
kev ntxhov siab vim pw tsaug zog
kiv taub hau
tsis hnov qab ntawm qhov mob,
npau suav phem
qaug zog,
kev nyuaj siab mob
lus txhais.

Noj Tsifran OD tuaj yeem ua rau mob taub hau, suav nrog migraines.

Los ntawm cov kab mob zis

Cov kev mob tshwm sim los ntawm qhov mob txeeb zig yog cov tsos mob hauv qab no:

kev tso zis cia
los ntshav, suav nrog thaum lub sij hawm mickey
cov zis hnyav tawm los
ua txhaum kev tso zis txoj cai,
kev puas tsuaj rau lub raum glomeruli,
tso cov protein nrog zis.

Los ntawm cov hlab plawv system

Cov tshuaj tuaj yeem cuam tshuam rau cov hlab plawv cov ntshav, vim qhov tshwm sim hauv qab no tshwm sim:

maj ntshav mus rau lub ntsej muag,
lub plawv dhia rau lub siab
txo qis siab
hloov pauv hauv lub plawv dhia.

Cov tshuaj tuaj yeem cuam tshuam rau lub plawv kev mob plawv, uas ua rau ntshav qis.

Hauv kev siv tshuaj, cov cim hauv qab no ntawm kev fab tshuaj yog muaj peev xwm ua tau:

kev tawm tsam ntawm daim tawv nqaij: hlwv, khaus, urticaria,
Lyell's syndrome, sawv cev los ntawm pob khaus, hlwv nrog cov ntsiab lus, tev tawv nqaij,
txog siav
me me scab nodules
daim tawv nqaij los ntshav,
kub cev ntawm cov tshuaj keeb kwm,
o kev mob ntawm lub suab thiab lub ntsej muag,
o ntawm daim tawv nqaij thiab cov qog ua kua xoos, ua rau muaj qhov tsim ntawm malignant exudative erythema.

Cawv tau zoo

Haus dej cawv thaum kho yuav ua mob rau daim siab thiab lwm yam hauv nruab nrog cev, vim tias cov tshuaj muaj qhov tsis zoo nrog haus cawv.

Siv rau lub sijhawm qub

Cov tshuaj yog contraindicated rau hauv kev kho mob hauv cov neeg laus neeg laus.

Lub sij hawm ntawm kev xeeb tub yog ib qho kev tawm tsam kev noj tshuaj.
Cov tshuaj kis mus rau niam mis, yog li ntawd, kom siv cov khoom, tus menyuam yuav tsum pauv mus rau ib qho khoom noj khoom haus lossis xaiv cov tshuaj sib txawv.
Lub hnub nyoog ntawm 18 xyoo yog contraindication, yog li Cifran tsis siv rau hauv kev kho menyuam yaus.
Cov tshuaj yog contraindicated rau hauv kev kho mob hauv cov neeg laus neeg laus.

Yuav ua li cas haus Tsifran

Cov ntsiav tshuaj ntawm cov tshuaj tua kab mob Cifran nrog rau cov lus ua ntej ST tau noj ntawm qhov ncauj tom qab noj mov. Lawv yuav tsum muab cov tshuaj ntxuav kom txaus nrog qhov ntau ntawm cov dej tsis muaj carbonated - txog iav. Nws tsis pom zoo kom tawg, ntxo ib ntsiav tshuaj. Cov neeg mob yuav tsum tau soj ntsuam qhov ntau npaum li cas ntawm kev noj tshuaj, zam kev noj tshuaj ntau dhau, uas yog fraught nrog cov teeb meem uas dhau los thaum cov tshuaj kho.

Raws li cov lus qhia rau kev siv Tsifran ST, cov tshuaj siv tom qab noj mov nrog cov kua haus txaus. Qhov pom zoo rau noj qhov ncauj txhua hnub rau cov laus tshaj 18 xyoo yog ob ntsiav tshuaj ib hnub ob zaug (ib qho tshuaj uas muaj ciprofloxacin thiab tinidazole 250/300 mg) lossis ib ntsiav tshuaj ib hnub ob zaug nrog noj ntau npaum cov tshuaj 500/600 mg. Lub chav kawm ntawm txoj kev kho yog nyob ntawm qhov mob hnyav ntawm cov kab mob thiab cov chaw kuaj mob thiab cov kab mob bacteriological.

Tsawg kawg peb hnub yuav tsum tau txais kev kho txuas ntxiv tom qab ploj ntawm kev kub taub hau, thiab lub caij nyoog nruab nrab yuav yog:

hnub nrog uncomplicated mob gonorrhea,
ob lub hlis nrog osteomyelitis,
tsawg kawg 10 hnub nyob rau hauv muaj xub ntiag ntawm streptococci thiab chlamydia,
thaum tsis muaj peev xwm coj cov ntsiav tshuaj ntawm lawv tus kheej los ntawm cov txheej txheem ntawm qhov ncauj, tus neeg mob tau txais kev sib tw infusion hauv kev poob qis los ntawm cov leeg ntshav.

Kuv tuaj yeem siv Cyfran thaum cev xeeb tub?

Nws tsis pom zoo kom sau ntawv siv CT ntawm Tsifran thaum cev xeeb tub, vim tias tinidazole muaj cov nyhuv carcinogenic thiab mutagenic, thiab ciprofloxacin hla tus txiv neej thiab cuam tshuam rau kev loj hlob ntawm tus me nyuam hauv plab. Ob qho tshuaj yeeb dej cawv tau pom nyob hauv mis ntawm tus pojniam thaum lactation, yog li ntawd kev pub mis niam tsis pom zoo. CT Digital tsis raug txwv rau kev pub niam mis. Koj yuav tsum tsis txhob pub mis niam lossis xaiv lwm qhov kev kho mob.

Cov yam ntxwv ntawm kev siv thaum tseem yog menyuam yaus

Cov lus qhia rau kev siv ST Tsifran tau hais tias nws yog txwv tsis pub rau cov menyuam yaus hnub nyoog qis dua 18 xyoo, tab sis nws raug tso cai siv cov tshuaj rau cov teeb meem tshwm sim los ntawm cov kab mob, nrog mob ntsws ntsws cystic fibrosis. Tom qab ntawd tus menyuam yaus ntawm 5-17 xyoo tuaj yeem haus dej haus ib qho tshuaj tua kab mob, lwm qhov kev zam yog kev tiv thaiv thiab kev kho mob ntawm tus mob ntsws ntsig. Tsis muaj ntaub ntawv qhia txog kev kawm ntawm cov tshuaj ntau npaum li cas rau cov menyuam yaus uas muaj kabmob hepatic thiab lub raum tsis ua haujlwm.

Cov tshuaj Cifran rau lub siab thiab lub raum ua haujlwm tsis zoo

Nrog kev ceev faj, nws raug nquahu kom noj Tsifran nrog cov tsiaj ntawv ua ntej ST rau cov neeg mob raum thiab mob siab tsis txaus, nrog rau cov neeg laus laus. Rau cov neeg mob zoo li no, cov tshuaj no raug txo mus txog ib nrab, ntxiv rau cov kws kho mob koom nrog saib lawv thaum lub sijhawm kho tag nrho. Nws yog ib qho tsim nyog yuav tsum tau soj ntsuam txhua lub sijhawm ntawm lub siab thiab lub raum, daim duab ua ntshav, qhov txawv me me ntawm qhov tsis zoo.

Sab nraud thiab contraindications

Cov lus qhia rau kev siv tshuaj tua kab mob ST Tsifran qhia cov kev sib txuas hauv qab no:

hypersensitivity tshua los yog cross-allergic cov lus rau derivatives ntawm cov tshuaj,
keeb kwm ntawm cov kab mob hematologic,
contraindicated nyob rau hauv cov neeg mob nrog inhibition ntawm pob txha hlwb hematopoiesis, nrog mob porphyria,
ua xua
cov leeg mob
organic txhab
cov me nyuam tsis tau muaj 18 xyoo,
nrog kev ceev faj nyob rau hauv cerebral arteriosclerosis, cerebrovascular kev raug mob, kev mob hlwb, mob vwm.

Kev phiv tshuaj los ntawm kev siv tshuaj tua kab mob Cifran yog cov kev tsis zoo hauv qab no los ntawm qee cov kab ke hauv lub cev:

tsis qab los noj mov, ntuav, raws plab, choleostatic jaundice (raws li pom), pom, kab mob siab,
mob taub hau, kiv taub hau, muaj zog dhau, mob hlwb, mob plab, mob plab, tshee tshee, pw tsis tsaug zog,
nce intracranial siab, kev nyuaj siab, tsis meej pem, thrombosis, tsaus muag, yastaw yauv tawm, pom kev,
tsis pom kev, hnov lus tsis zoo,
tachycardia, lub plawv dhia tsis ua hauj lwm, tsis muaj ntshav siab,
leukopenia anemia, thrombocytopenia, anemia,
hematuria, polyuria, tso zis cia, nephritis, dysuria, zam kev quaj,
mob taub hau, mob tso zis heev, tso quav, mob ntshav,
arthralgia, mob caj dab, mob caj dab, tendovaginitis, asthenia, myalgia, candidiasis, mob plab, mob hlwb.

Npaum licas

Xaj hauv online chaw muag tshuaj nrog xa lossis yuav los ntawm tus kws muag tshuaj tuaj yeem ua ntsiav tshuaj Tsifran. Thaum muas nyob rau hauv Moscow thiab St. Petersburg, koj tuaj yeem xaiv qhov kev coj ua ntawm cov tshuaj nquag ntawm cov tshuaj. Yog li, 10 ntsiav tshuaj ntawm 500 + 600 mg yuav raug nqi 357 rubles, thiab 250 + 300 mg nyob rau hauv tib tus nqi - 151 rubles. Hauv Is Taws Nem, tus nqi no raug txo los ntawm kwv yees li 10%, tab sis tus nqi xa los ntawm courier ntxiv.

Los ntawm cov tshuaj yeeb dej caw, kev txiav txim ntawm pharmacological thiab cov yam ntxwv, cov piv txwv ntawm Tsifran ST, tsim los ntawm Indian thiab domestic cov lag luam, muaj qhov txawv:

ntsiav tshuaj Tsiprolet, Tsipro-TK, Tsifomed-TZ, Grandazole, Zoksan-TZ, Zoloxacin, Orzipol, Ofor, Polymik, Tifloks, Roksin, Stillat,
Grandazole Txoj kev lis ntshav kua
hmoov rau Norzidime tov,
Cephoral, Quintor, Tsiprobay.

Maxim, 23 xyoo, Tsifran ST tau sau ntawv rau kuv los ntawm kws kho mob tom qab kuaj pom mob raws ntu. Kuv coj ib chav kawm ntawm cov tshuaj tua kab mob thiab pom ib qho kev txhim kho - cov pos hniav nres whining, qhov mob pib ploj mus, nws muaj peev xwm mus txuas ntxiv kev kho mob thiab muab ib lub kaus mom. Cov tshuaj siv nyiaj zoo!

Nina, muaj 30 xyoo. Muaj mus ncig, Kuv ntes tau mob plab zom mov. Nws phem heev, tus kws kho mob tau sau tshuaj tua kabmob rau kho kom sai. Nws tshuaj rau kuv Tsifran ntau npaum li cas, ntxiv rau kev noj tshuaj ntxiv. Peb tau tswj kom tshem tawm tus kabmob hauv ib lub lim tiam.

Kev cuam tshuam nrog lwm yam tshuaj

Tsifran yog tsim los ntawm cov yam ntxwv hauv qab no ntawm kev sib cuam tshuam nrog lwm yam tshuaj:

Txo cov kev nqus ntawm cov khoom nquag thaum siv antacids nyob rau hauv uas muaj txhuas hydroxide lossis magnesium hydroxide.
Ib qho kev nce siab ntawm cov tshuaj uas muaj cov piam thaj kom txo qis, cov tshuaj anticoagulants, xanthines thiab Theophylline.
Txo kev nqus ntawm ciprofloxacin thaum siv cov didanosine.
Cov tsos ntawm kev poob cev thiab lub ntsej muag poob siab vim qhov siv tizanidine.
Kev nce ntxiv ntawm kev pheej hmoo ntawm kev tshwm sim phiv thaum noj cov tshuaj tsis-steroidal anti-inflammatory tshuaj thiab analgesics.
Txo cov poom phenytoin ntau.
Ib qho kev nce tsis zoo rau lub raum thaum kho nrog Cyclosporine.
Kev nce ntxiv hauv kev ua tau zoo thaum siv ua ke nrog metronidazole, clindamycin thiab aminoglycosides.
Kev maj mam tshem tawm ntawm lub cev thiab nce qhov kev xav ntawm cov khoom nquag thaum siv cov tshuaj uricosuric.
Kev nrawm nrawm ntawm Cyfran vim yog siv cov tshuaj metoclopramide.

Txais tos ntawm Tsifran OD yog qhov txawv txav ntawm kev muaj peev xwm ntawm kev txhim kho cov kev mob tshwm sim thaum noj cov tshuaj tsis-steroidal anti-inflammatory tshuaj thiab analgesics.

Cov tshuaj ntawm cov tshuaj suav nrog:

Ciprobay yog cov tshuaj hauv tebchaws German uas muaj 250 lossis 500 mg ntawm ciprofloxacin.
Ciprinol ntsiav tshuaj nrog cov nyhuv antibacterial.
Siflox yog yeeb tshuaj nrog ntau yam kev cuam tshuam cov kab mob bactericidal.
Qhov tseeb yog cov tshuaj tua kab mob hauv cov dej uas cov tshuaj nquag hu ua hemifloxacin mesylate.
Leflobact yog ib qho tshuaj tiv thaiv kev ua kom rog nrog 250 lossis 500 mg ntawm levofloxacin hemihydrate. Cov tshuaj tau zoo tawm tsam chlamydia, staphylococci, ureaplasma, legionella, enterococci thiab kab mob gram-negative.
Gatifloxacin yog cov tshuaj tua kab mob los ntawm cov pab pawg ntawm fluoroquinolones. Nws zwm rau tiam 4 lawm.
Cifran ST yog ib qho tshuaj antimicrobial uas muaj 500 mg ntawm ciprofloxacin thiab 600 mg ntawm tinidazole. Muaj nyob hauv Is Nrias teb. Nws yog siv los ua kab mob uroanaseptic hauv kev kho mob, thiab hauv kev kho hniav, otolaryngology thiab lwm thaj chaw ntawm cov tshuaj.

Dab tsi yog qhov txawv ntawm Tsifran thiab Tsifran OD

Qhov peculiarity ntawm Cifran OD cuam tshuam nrog cov nyhuv elongated, uas txo qis zaus ntawm kev tswj hwm ntawm cov tshuaj.

Kev tshuaj xyuas ntawm cov kws kho mob thiab cov neeg mob txog Tsifran OD

Evgeny Alexandrovich, cov kws kho mob dav dav

Kev siv Cifran OD pab daws cov teeb meem sib kis ntau, txij li ntau tus kab mob yog rhiab rau ciprofloxacin. Cov tshuaj yog tus cwj pwm los ntawm lub sijhawm ntev, uas muaj qhov cuam tshuam zoo ntawm kev kho.

Irina, 41 xyoo, Togliatti

Vim yog cov nqaij mos muag kab mob hauv ntshav qab zib, Cifran tau raug muab tshuaj. Cov tshuaj tau pab nyob rau hauv ob peb hnub kom txo cov tsos mob thiab kev hnyav ntawm o. Cov kev kho mob ntxiv tau coj tawm hauv tsev kho mob vim tias yuav tsum tau muaj kev tswj hwm. Qhov tsis zoo ntawm cov tshuaj yog qhov loj ntawm cov ntsiav tshuaj, yog li nws nyuaj rau kev nqos lawv.

Elena, 39 xyoo, Irkutsk

Nrog kev pabcuam ntawm Tsifran, OD tau tshem ntawm tus kabmob. Txawm li cas los xij, kev kho mob tau cuam tshuam los ntawm cov kev mob tshwm sim, uas muaj ntau yam. Tom qab noj thawj lub ntsiav tshuaj, kev iab tawm nyob rau hauv lub qhov ncauj, vim tias cov khoom noj tau hloov mus rau ib qho kev sim. Tom qab kiv taub hau, tsaug zog, thiab xeev siab. Cov tshuaj muaj txiaj ntsig, tab sis vim tias muaj cov kev mob tshwm sim tom qab no, kuv yuav txwv tsis pub siv cov khoom lag luam rau lwm zaus.

Kev cuam tshuam rau kev muaj peev xwm tsav tsheb thiab cov txheej txheem nyuaj

Nyob rau tag nrho lub sijhawm ntawm kev kho mob, koj tsis tuaj yeem koom rau hauv kev nqis tes ua cov haujlwm uas muaj peev xwm, suav nrog kev tswj hwm kev thauj mus los, vim Tsifran OD tuaj yeem ua rau txo qis ntawm psychomotor cov kev cuam tshuam thiab saib xyuas.

Cev xeeb tub thiab lactation

Nws tsis pom zoo kom siv Tsifran OD thaum lub sijhawm siv cev xeeb tub.

Txij li thaum ciprofloxacin tawm hauv niam mis, yog tias yuav tsum tau muab tshuaj rau lub sijhawm thaum lactation, kev pub mis niam yuav tsum tsis ua mus ntxiv.

Siv rau thaum yau

Lub sijhawm teem ntawm Cyfran OD rau kev kho mob ntawm cov neeg mob hnub nyoog qis dua 18 xyoo yog contraindicated, vim hais tias cov txheej txheem ntawm pob txha tsis tau ua tiav.

Thaum tsis ua haujlwm lub raum

Kev siv Cifran OD yog contraindicated rau hauv cov neeg mob uas mob raum tsis ua haujlwm nrog CC tsawg dua 29 ml / min, suav nrog cov mob ntawm hemodialysis thiab peritoneal lim ntshav.

Kev ceev faj yuav tsum siv nyob rau hauv lub raum poob nrog CC 35-50 ml / min.

Nrog lub siab ua haujlwm tsis zoo

Nrog kev ceev faj, nws yog ib qho tsim nyog yuav tsum tau sau ntawv rau Tsifran OD nrog daim siab ua haujlwm siab.

Siv rau lub sijhawm qub

Kev ceev faj yuav tsum tau muab rau kev teem sij hawm ntawm fluoroquinolones rau cov neeg mob laus, suav txog qhov ua rau muaj feem cuam tshuam ntawm lub hnub nyoog txo qis hauv lawv lub raum kev ua haujlwm, thiab kev kho cov tshuaj ntau ntxiv piv rau qhov kev ua txhaum cai.

Nrog tib lub sijhawm siv Tsifran OD:

metronidazole, beta-lactams, clindamycin, aminoglycosides thiab lwm yam tshuaj tua kab mob: ua rau mob synergism. Rau kev kho mob kom zoo rau kev mob kis los ntawm Pseudomonas tshwj xeeb, kev sib xyaw nrog ceftazidime thiab azlocillin, kab mob streptococcal nrog cov tshuaj tua kab mob beta-lactam (meslocillin, azlocillin), staphylococcal kab mob nrog vancomycin, isoxazolpenicillin kab mob, anaerobic aminerocytamines, anaerob
theophylline: ua rau kom nws cov siab xav hauv ntshav ntshav,
tizanidine: Ua rau muaj kev pheej hmoo ntawm cov lus txo hauv cov ntshav siab, cov tsos ntawm kev nkees,
cov tshuaj tiv thaiv kab mob thiab tshuaj thaiv kab mob: txo qhov nqus ntawm Cyfran OD thaum noj qhov ncauj,
didanosine: pab txo qhov nqus ntawm ciprofloxacin,
cov tshuaj tiv thaiv kab mob uas suav nrog aluminium lossis magnesium hydroxide nyob rau hauv muaj pes tsawg leeg: pab txhawb kom txo qis hauv kev nqus ntawm ciprofloxacin, yog li no kev sib xyaw no yog contraindicated,
tshuaj uas thaiv cov tubular tso pa tawm, suav nrog probenecid: txo qis raum tsis ua haujlwm ntawm ciprofloxacin,
analgesics: ua rau muaj kev cuam tshuam ntau ntxiv los ntawm ciprofloxacin los ntawm lub hauv nruab siab,
phenytoin: yuav txo qis lossis nce koj cov ntshav plasma concentration,
sucralfate: txo qhov nqus ntawm Cyfran OD,
histamine H2 receptor antagonists: tsis muaj kev cuam tshuam los ntawm kev sib tw tshuaj rau qhov muaj kev nyab xeeb ntawm kev noj tshuaj ciprofloxacin,
qhov ncauj anticoagulants, suav nrog warfarin thiab nws cov lus qhia: txhim kho lawv cov txiaj ntsig, yog li ntawd, thaum ua ke nrog cov tshuaj, kev tshawb fawb tsis tu ncua ntawm cov ntshav coagulation system yuav tsum,
glyburide: tuaj yeem ua rau mob ntshav qab zib siab heev,
qhov ncauj hypoglycemic tus neeg sawv cev, caffeine thiab lwm yam xanthines: nce lawv cov qib siab thiab txuas ntxiv ua kom ntev T1 / 2,
metoclopramide: nrawm nws qhov nqus,
uricosuric cov neeg sawv cev: yuav luag 50% ua rau qeeb ntawm kev tshem tawm ciprofloxacin, ua rau muaj kev nce ntxiv hauv nws cov ntshav siab,
cyclosporine: txhim kho nws cov nyhuv nephrotoxic. Txij li thaum muaj kev nce qib hauv cov ntshiab creatinine, nws qib yuav tsum raug tswj 2 zaug hauv ib lim tiam.

Cov lus thiab cov xwm txheej ntawm kev cia

Khaws tsis ncav cuag ntawm cov menyuam yaus.

Muab cia rau qhov kub thiab txias li 25 ° C hauv qhov chaw qhuav.

Txee lub neej yog 2 xyoos.

Cov Cai Siv Tshuaj So

Tso tawm los ntawm kev kho mob.

Kev txheeb xyuas txog Tsifran OD

Kev tshuaj xyuas ntawm Tsifran OD yog qhov zoo, lawv qhia tias muaj kev ua haujlwm ntau los ntawm cov tshuaj hauv kev kho mob ntau yam kab mob.

Cov neeg mob qhia tias muaj kev mob siab rau ncaj ncees ntawm Cifran OD, tsis muaj cov kev mob tshwm sim los ntawm txoj kev mob tshwm sim sai sai, qhov pib sai ntawm kev kho nrog mob hnyav.

Tus nqi ntawm Tsifran OD hauv cov khw muag tshuaj

Tus nqi ntawm Tsifran OD 1000 mg rau ib pob uas muaj 10 ntsiav tshuaj yuav yog 267–325 rubles. 10 ntsiav tshuaj ntawm Tsifran OD 500 mg nqi 170–206 rubles.

Cov yam ntxwv dav dav. Muaj pes tsawg leeg:

Cov ntsiav tshuaj, coated, ua lub sijhawm ntev, hauv 1 lub rooj.
ciprofloxacin 500 mg, 1000 mg
hauv qhov ncauj tawm 5 pcs., nyob hauv ib pob ntawv thawv los yog 1 hlwv.

Kev piav qhia Ntsiav tshuaj "Tsifran® OD 500 mg": oval, los ntawm dawb mus yuav luag dawb, zaj duab xis-txheej, luam tawm nrog cov kua zaub mov dub - "Cifran OD 500 mg".
Cifran® OD 1000 mg ntsiav tshuaj: oval, los ntawm dawb mus yuav luag dawb, zaj duab xis-txheej, luam tawm nrog cov zaub mov xim dub - Cifran OD 1000 mg.

Daim Ntawv Thov Nta:

Hauv qee cov neeg mob uas tau txais fluoroquinolones, kev tsom xam qhov muag tau pom tau. Kev tiv thaiv tshav ntuj ntev thiab ntsuas UV ntau dhau yuav tsum zam. Yog tias qhov kev tawm tsam qhov txawv txav, pom zoo kom tsis txhob siv cov tshuaj no. Txij li thaum Cifran is OD yog ib qho tshuaj uas muaj peev xwm thim rov qab los ua rau lub raum, nws tsis pom zoo rau kev siv rau cov neeg mob uas tsis ua haujlwm lub raum, nrog Cl creatinine

Tsifran OD - kev noj tshuaj ntawm lub sijhawm ntev, ntsiav tshuaj hauv lub plhaub. Lub npe txais yuav nyob rau hauv kev kho mob thoob ntiaj teb yog ciprofloxacin.

Kev piav qhia thiab tshuaj noj

Cov tshuaj yog nthuav tawm nyob rau hauv daim ntawv ntawm oval dawb ntsiav tshuaj. Txhua tus yog them nrog zaj duab xis. Ntawm ib sab tes muaj qhov cim - Cifran ODSOOMG. Tus cwj mem khoom noj yog siv los sau khoom. Ntawm scrapping, lub ntsiav tshuaj kuj yuav muaj qhov zas me ntsis.

Qhov no tseem ceeb heev! Kev txiav txim ntawm cov tshuaj yog tsom rau kev puas tsuaj ntawm ntau qhov kev tiv thaiv kab mob microflora (kab mob). Cov tshuaj yog kws kho rau cov txheej txheem pathological ntawm kev kis tus kab mob.

Daim ntawv qhia tshuaj - ntsiav tshuaj, ntim hauv hlwv ntawm 5 daim. Hauv lub thawv 1 lossis 2 lub hlwv.

Cov tshuaj tiv thaiv tseem ceeb ntawm cov tshuaj yog ciprofloxacin.

"Tsifran OD" (500 mg) - muaj 500 mg ntawm cov nquag ua haujlwm,
"Tsifran OD" (1000 mg) - 1000 mg ntawm cov tshuaj ua kom nquag plias.

Alginate thiab sodium bicarbonate,
Magnesium stearate,
Talc,
Silica

Tshuaj lom neeg muaj pes tsawg leeg ntawm lub plhaub:

Cov ntsiav tshuaj yog siv raws li kev kho mob rau pathologies provoked by pathological microorganisms:

Kev mob pob txha
Pathologies ntawm lub ntsws ua pa ntawm qhov kis tau, uas yog nrog los ntawm o,
Txawv ntawm cystitis, pyelonephritis,
Tus mob prostatitis yog ib hom kab mob,
Gonorrhea
Kev mob plab hauv plab nrog cov teeb meem (kev kho yog kho nrog metronidazole),
Cov txheej txheem pathological ntawm daim tawv nqaij ntawm ib qho kev sib kis,
Kis kab mob pathological hauv pob qij txha thiab cov pob txha pob txha,
Cov quav ua rau mob los ntawm tus kab mob,
Tus mob typhoid fever,
Tus mob cholecystitis.

Noj cov tshuaj los ntawm pab pawg tshwj xeeb ntawm cov neeg mob

Nrog mob hnyav rau lub raum ua haujlwm.

Nrog cov ua haujlwm tsis zoo hauv lub cev, ib nrab-lub neej ntawm cov tshuaj nquag nce ntxiv. Muab qhov tseeb no, tus kws kho mob yuav tsum kho cov kev siv ntau npaum li cas thiab lub sijhawm kho mob li cas.

Nrog lub siab ua haujlwm tsis zoo.

Cov kev tshawb fawb tau tshawb fawb hauv cov neeg mob qog ntshav, kev hloov pauv tseem ceeb ntawm cov tshuaj tsis tau soj ntsuam. Thaum muab tshuaj kho, nws yuav tsum tau yug los hauv lub siab tias tsis muaj kev tshawb fawb tau ua rau cov neeg mob siab tsis ua haujlwm.

Tsifran OD thiab cev xeeb tub.

Kev pom zoo lub peev xwm tob tob ntawm cov tshuaj, noj Cifran OD thaum cev xeeb tub thiab lactation tsis pom zoo.

Qhov no tseem ceeb heev! Lub sijhawm pub mis, kev teem sijhawm siv cov tshuaj muaj peev xwm ua tau yog tias muaj kev pheej hmoo rau leej niam lub neej ntau dua qhov phom sij rau menyuam, tabsis kev pub mis rau menyuam yuav tsum tau tsum.

Sab sij huam

Digestive plab hnyuv siab raum:

Xeev siab (nyob rau hauv tsis tshua muaj mob, ntuav)
Lub rooj zaum thab
Kev tsis xis nyob thiab tsam plab hauv plab,
Zoo nkaus li tsam plab hauv plab
Kev Mob Nkeeg
Kab mob siab
Yog tias tus neeg mob tau mob siab rau lub siab, cov tsos mob daj ntseg yuav pom.

Mob leeg:

Kev ntshai ntawm lub teeb
Pw tsaug zog cuam tshuam
Vauv
Kiv taub hau
Qaug zog
Hnov Tias Txoj Kev Plees
Tsis meej pem txoj kev xav
Nyuaj siab hauv lub xeev.

Hnov kabmob siab:

Saj distortion,
Distortion ntawm kev pom xim,
Tsis hnov tsw
Lub suab txuas rau hauv pob ntseg.

Lub plawv mob:

Tachycardia
Siab surges,
Ua ntsej muag tawm ntawm lub ntsej muag
Lub plawv dhia jumps.

Hematopoietic system:

Mob Leukocytosis
Mob Kev Plab
Leukopenia
Eosinophilia.

Cov kab mob zis:

Cov hlab ntsws ua paug (thaum tsis tshua muaj mob, lub raum tsis ua haujlwm),
Hematuria
Dysuria
Tso zis cia rau hauv lub cev,
Albuminuria

Ua xua:

Khaus thiab khaus
Cov hlwv yuav tshwm sim uas nrog los ntshav,
Cov kiav txhab thiab pob tw me me tshwm sim,
Ntawm daim tawv nqaij, taw tes rau cov ntshav hem,
Muaj qee zaus, o ntawm lub ntsej muag thiab lub suab npe yog ua tau,
Ua tsis taus pa
Vasculitis
Ntau hom erythema,
Necrolysis.

Musculoskeletal system:

Mob caj dab
Neej Hmoob
Arthralgia,
Tenovaginitis.

Qhov no tseem ceeb heev! Muaj qee kis, cov neeg mob ua rau tawm hws ntau dhau, feem ntau tsis muaj zog, candidiasis yuav tsim muaj.

Kev cuam tshuam nrog lwm yam tshuaj

Thaum kho nrog Cifran OD thiab glucocorticosteroids, cov neeg mob hnub nyoog 60 xyoo rov nce siab tseem yuav muaj kev puas tsuaj rau cov leeg.
Thaum cov tshuaj uas txhawb kev ua pa ntawm cov zis yog tshuaj ua ke nrog Cifran OD, qhov ntxim nyiam ntawm nephrotic nce.
Muaj kev pheej hmoo siab heev tshwm sim los ntawm cov teebmeem neurotoxic thaum kho nrog Cifran OD thiab lwm cov tshuaj tsis-steroidal los tiv thaiv.
Nws yog ib qho tseem ceeb kom muaj ob-teev so ntawm kev txais tos ntawm antacids, tshuaj raws li hlau thiab Cyfran OD. Qhov so qis tshaj plaws yog ob teev, txwv tsis pub ua haujlwm ntawm cov tshuaj txo qis zuj zus.
Cov khoom lag luam muaj kev cuam tshuam tsis zoo txaus siab npaum li cas ntawm kev nqus ntawm cov khoom xyaw nquag.

Dab tsi los saib

Cov neeg mob uas tau txais kev kho mob fluoroquinol qhia pom tias muaj kev sib deev ntau dua. Rau lub sijhawm ntawm kev kho, koj yuav tsum txwv qis kev tiv thaiv tshav ntuj thiab duab ci hluav taws xob. Yog tias qhov ua rau muaj teeb meem tshwm sim ntau ntxiv, tus kws kho mob txiav txim siab txo qhov ntau npaum lossis txiav cov tshuaj, hloov nws nrog lwm cov tshuaj.

Tsifran OD muaj kev cuam tshuam tshuaj lom ua rau lub raum. Nws tsis pom zoo kom sau ntawv tshuaj rau:

Mob raum tsis zoo,
Hemodialysis
Kev lim ntshav.

Tsifran OD tuaj yeem ua rau kev txhim kho pseudomembranous colitis. Cov kab mob pathological tuaj yeem tshwm sim hauv cov ntawv me lossis hauv ib daim ntawv uas ua rau muaj kev phom sij rau tus neeg mob lub neej. Yog tias kev kho mob nrog nrog mob plab zawv thiab lub caij ntev, yog tias qhov quav tsis zoo tshwm sim sai sai tom qab nws, kev tshawb nrhiav yuav tsum tau ua kom tshem tawm qhov ntxim nyiam ntawm pseudomembranous mob plab. Yog tias kev kuaj mob tau lees paub, nws yog ib qho tsim nyog yuav tsum tso tseg Tsifran OD tam sim ntawd thiab kev kho mob cov tsos mob.

Txhawm rau tshem tawm qhov ntxim nyiam ntawm crystalluria, koj tsis tuaj yeem dhau qhov tso cai tso cai thiab haus dej kom ntau thoob plaws hauv lub chav kawm ntawm kev kho.

Cov tshuaj yog yam siv rau kev noj qab haus huv, yog tias tus neeg mob muaj:

Tshuaj qaug dab peg
Cramps
Vascular pathology,
Hlwb puas tsuaj.

Cov kev tawm tshiab no tuaj yeem ua rau muaj kev phom sij tsis zoo los ntawm lub hauv nruab siab.

Hauv kev kho mob, muaj qee kis ntawm cov leeg txiav thaum kho fluoroquinol kho tau. Ntawm thawj qhov xwm txheej phom sij - tsis xis nyob rau ntawm cov leeg thiab cov tsos mob ntawm lub raum mob raum - koj yuav tsum tau sab laj rau tus kws kho mob tshwj xeeb los kho qhov tshuaj ntau npaum lossis tshem tawm cov tshuaj.

Qhov no tseem ceeb heev! Rau lub sijhawm ntawm txoj kev kho, ib qho yuav tsum tau txwv tsis txhob cuam tshuam nrog lub hnub thiab tshem tawm cov hom kev ua haujlwm uas qhov kev mloog zoo yog qhov tsim nyog, thiab txwv kev tswj kev thauj.

Cia thiab txee lub neej

Cov tshuaj raug muab khaws cia ntawm kub txog +25 degrees, hauv qhov chaw tsaus thiab qhuav. Tsifran OD tseem muaj txiaj ntsig ib xyoos.

Basigen - los ntawm 15 rubles,
Ciprofloxacin - los ntawm 17 rubles,
Ciprofloxacin AKOS - los ntawm 20 rubles,
Ciprofloxacin Bufus - los ntawm 25 rubles,
Ciprofloxacin SOLOpharm - los ntawm 30 rubles.

Cov kws kho mob hais li cas txog cov tshuaj.

Nikolai Petrovich, kws kho mob: Kuv sau ntawv rau tshuaj rau purulent-inflammatory pathological txheej txheem. Cov kev kho mob tau pom nyob rau hauv thawj hnub. Kuv sau cifran OD ua ib txoj kev kho, nrog rau rau prophylaxis ua ntej kev phais mob. Raws li rau qhov luv luv - cov ntsiav tshuaj muaj qhov loj txaus, nws nyuaj rau nqos.

Olga Petrovna, kws kho mob poj niam: Hauv kev sib piv nrog lwm cov tshuaj tua kab mob, Tsifran OD muaj cov txiaj ntsig zoo tshaj plaws, qhov tsawg kawg ntawm cov kev mob tshwm sim yog pom. Kuv xav nco ntsoov lub siab ua haujlwm ntawm cov ntsiav tshuaj. Yog tias muaj cov ntaub ntawv pov thawj tsim nyog, nws yog Tsifran OD uas tau raug tsa los ua thawj qhov chaw.

Yuav ua li cas cov neeg mob hais txog cov tshuaj.

Vera, 39 xyoo: Tsifran OD ua ke nrog Smartprost tau pab kuv tus txiv los ntawm prostatitis.

Oksana, 28 xyoo: Ntau tus ua tsaug rau tus kws kho mob uas cawm kuv tus tub los ntawm tsev kho mob nrog ob leeg mob ntsws. Nws tau tsa Tsifran OD, thiab tom qab 3 hnub nws tus tub pib rov zoo, thiab ob lub lis piam tom qab lub sijhawm sib tw ntawm lub ntsws tau pom tias qhov kev hem thawj ntawd dhau mus.

Nikita, 57 xyoo: Kuv haus yeeb tshuaj thaum mob qa, qhov kub rov tuaj nyob li qub thaum yav tsaus ntuj. Txawm li cas los xij, Tsifran OD ua rau kuv muaj kev phiv - qhov ncauj qhuav, mob taub hau, zoo li nkees.