Lwm tiam ntshav qab zib mellitus tshuaj thiab cov tshuaj rau ntshav qab zib hom 2

Cov suab thaj txo cov nyhuv ntawm cov tshuaj yog los txhawb lub hlwb pancreatic los tsim cov tshuaj insulin, txhim kho kev nqus ntawm cov piam thaj los ntawm cov leeg, thiaj li txo nws cov ntshav hauv cov ntshav. Nws inhibits zus tau tej cov piam thaj hauv lub siab.

Cov tshuaj txhim kho cov lipid metabolism, ua kom cov rog hauv cov ntshav tsawg, txo cov ntshav txhaws, tiv thaiv kev mob ntshav qab zib (retinopathy, hlab plawv).

Ua tsaug rau lub micronized qauv, cov tshuaj sai dua thiab ua tiav adsorbed nyob rau hauv lub plab, muaj meej bioavailability.

Kev taw qhia thiab tsuas tshuaj

Hom 2 mob ntshav qab zib mellitus nrog kev tsis ua tiav ntawm cov tshuaj tiv thaiv kab mob thiab kev rog.

Cov tshuaj yog kws kho mob sau ntawv los ntawm kws kho mob. Cov koob tshuaj yog txiav txim siab ntawm tus kheej, noj mus rau hauv tus account qib ntawm cov piam thaj ntawm lub plab khoob thiab 2 teev tom qab noj mov.

Thawj koob tshuaj txhua hnub ntawm 1.75 mg ntawm mannyl yog 0.5-1 ntsiav tshuaj. Maj mam nce lub koob tshuaj kom ib txwm muaj suab thaj. Qhov siab tshaj plaws yog peb ntsiav tshuaj ib hnub.

Txhawm rau nce cov tshuaj, lawv hloov mus rau 3.5 mg mannil pib txij li 0.5-1 ntsiav tshuaj ib hnub.

Maninil 5 mg pib nrog 0.5 ntsiav tshuaj ib hnub. Thaum qhia, kev noj tshuaj rau txhua hnub yog maj mam nce mus rau 15 mg. Kev noj tshuaj ntau dua tsis ua rau muaj suab thaj txo qis ntawm mannyl.

Maninil tau noj ib nrab ib teev ua ntej noj mov. Cov ntsiav tshuaj yog ntxuav nrog dej tsis ntxo. Cov tshuaj txhua hnub ntau dua 2 ntsiav tshuaj tau muab faib rau thaum sawv ntxov thiab yav tsaus ntuj. Nce qhov ntau ntxiv hauv kev saib xyuas ntawm tus kws kho mob.

Yog tias qhov siab tshaj plaws ntawm cov tshuaj yog qhov ua tsis tau zoo, lo lus nug ntawm ntxiv insulin nrog maninil tau raug daws.

Cov Tshuaj Tiv Thaiv:

• ntshav qab zib hom 1
• ntshav qab zib,
• mob ntshav qab zib coma, ketoacidosis,
• decompensated pathologies ntawm ob lub raum thiab mob siab,
• muaj menyuam hauv plab, pub niam mis,
• intolerance rau sulfanilurea npaj.
• Cov tshwm sim tsis zoo:
• ntshav qab zib,
• Cov tsos mob dyspeptic
• kev fab tshuaj tsis haum

Maninil yuav tsum muaj kev ceeb toom rau cov neeg mob tom qab 60 xyoo (kev phom sij ntawm hypoglycemia), zoo li rau cov neeg ua haujlwm uas yuav tsum muaj kev kub siab.

Yuav ua li cas nkag siab cov npe ntawm cov tshuaj uas txo cov ntshav qab zib

Cia kuv nco koj, cov phooj ywg, tias txhua yam tshuaj muaj nws tus kheej thoob ntiaj teb uas tsis yog tus tswv ntawm lub npe, nws yog luv luv hu ua INN. Lub npe no tau qhia nyob rau hauv cov tshuaj uas muaj lub siab nyiam thaum nws tso tawm hauv chaw kho mob. Thiab cov npe uas koj pom ntawm ntim hauv khw muag tshuaj yog cov npe lag luam ntawm lub tuam txhab pharmacological. INN ntawm kev ntim khoom feem ntau sau ua ntawv me me txoj cai nyob rau hauv lub npe lag luam tawm. Qee zaum cov npe no ua ke.

Yog li, kuv yuav tsis tham txog ib tus neeg sawv cev rau hauv qab zib kom tsawg, piv txwv li, tshuaj ntsuab (maninil), tab sis hais txog ib pawg tshuaj raws li cov tshuaj glibenclamide. Thiab ntawm chav kawm, Kuv yuav muab cov piv txwv thiab cov piv txwv ntawm cov npe kev lag luam thiab lub teb chaws ntawm cov chaw tsim tshuaj paus ua suab thaj.

Kuv xav tham txog txhua pab pawg qab zib cov tshuaj txo qis qis, tab sis ua ntej uas kuv txiav txim siab "tshaj tawm tag nrho cov npe", thiab tom qab ntawd piav qhia luv luv txhua pawg nrog kev siv rau kab lus.

Maninil - daim ntawv tso tawm

Manilin, daim duab uas tau muab nthuav tawm hauv ntu no, muaj cov ntsiab lus tseem ceeb ntawm kev siv tivthaiv glibenclamide thiab cov ntsaws:

• Methyl hydroxyethyl cellulose,
• Lactose Monohydrate,
• Qos yaj ywm starch
• Magnesium stearate,
• Silicon dioxide
• Dye Ponceau 4R.

Nws yog qhov yooj yim los txheeb xyuas cov khoom lag luam ntawm German chaw tsim tshuaj lag luam Berlin-Chemie (Menarini Group): cov ntsiav tshuaj nrog cov pinkish tint muaj chamfer thiab txoj kab sib cais ntawm ib sab. Nyob ntawm seb ntau npaum li cas, ib ntsiav tshuaj tuaj yeem muaj 3.5-5 mg ntawm lub ntsiab kev ua haujlwm.

Hauv cov khw muag tshuaj lub khw muag tshuaj, tuaj yeem yuav tshuaj nrog rau cov ntawv yuav tshuaj noj. Hauv Maninil, tus nqi yog peev nyiaj ntau - ntawm 140 txog 185 rubles. Cov tshuaj tsis tas yuav muaj cov xwm txheej tshwj xeeb rau kev cia, tab sis kev nkag ntawm cov menyuam yaus thiab kev tshav ntuj ncaj qha yuav tsum tau txwv. Lub txee lub neej ntawm cov ntsiav tshuaj yog 3 xyoos, cov tshuaj tas sij hawm yog raug pov tseg.

Pharmacological tau

Lub luag haujlwm tseem ceeb ntawm glibenclamide yog los txhawb lub stimulate-hlwb ntawm cov islets ntawm Langerhans, lub luag haujlwm tsim khoom ntawm lawv tus kheej insulin. Activity-kev ua ub ua no tau ncaj qha mus rau theem ntawm glycemia thiab nws ib puag ncig. Tom qab siv, cov ntsiav tshuaj tau nqus nrawm ntawm phab ntsa hnyuv. Tus nqi ntawm kev nqus ntawm qhov ntim ntawm cov ntsiab lus ntawm lub plab thiab lub sijhawm nws tau ntim nrog cov zaub mov tsis cuam tshuam. Nrog plasma protein, cov tshuaj nkag mus rau hauv kev sib cuag los ntawm 98%. Lub ncov ntawm nws qib hauv cov ntshav cov ntshav tau pom tom qab 2 thiab ib nrab teev thiab nce mus txog ntawm 100 ng / ml. Ib nrab-lub neej yog li 2 teev, thaum noj ib os - 7 teev. Nyob ntawm saib ntawm daim duab soj ntsuam kab mob, hauv cov neeg mob ntshav qab zib lub sijhawm no tuaj yeem yog 8 lossis 10 teev.

Cov tshuaj yog metabolized feem ntau hauv daim siab, hloov pauv nrog kev pab ntawm tsis-pathocytes rau ob hom metabolites: 3-cis-hydroxy-glibenclamide thiab 4-trans-hydroxy-glibenclamide.

Nws tau txais kev sim paub tias cov khoom noj metabolites tsis ua rau kev mob ntshav hauv lub ntsej muag, tshem tawm los ntawm lub raum thiab cov kua tsib los ntawm lub cev tag nrho hauv 2-3 hnub.

Yog tias lub siab ua tsis tau zoo, cov tshuaj raug khaws cia hauv cov ntshav ntev dua. Nrog pathologies ntawm ob lub raum nrog zis, nws tau tshem tawm nrog kev ncua, lub sijhawm ntawm uas nyob ntawm qhov mob hnyav ntawm kev ua haujlwm tsis txaus ntseeg ntawm lub cev.

Tshwj xeeb, nrog cov mob me mus rau qib hauv lub raum kev ua haujlwm dhau los, kev nruam taws tsis yog pauv. Nrog creatinine tshem tawm ≤30 ml / min, tus nqi ntawm kev tshem tawm cov metabolites txo, feem nce cov theem ntawm cov tshuaj hauv cov ntshav. Cov xwm txheej zoo sib xws rau Maninil xav tau ib feem kaum ntawm cov ntau npaum lossis tshem tawm (feem ntau yog muaj li ntawd, cov tshuaj insulin hauv qab daus).

Leej twg yog Maninil rau?

Cov tshuaj yog tsim los tswj hom mob ntshav qab zib hom 2 (uas tsis yog-insulin-yam ua qauv). Cov ntsiav tshuaj tau muab rau cov neeg mob ntshav qab zib ntxiv rau qhov tsis tas yuav npaj siv tom qab hloov txoj kev ua neej (kev noj zaub mov kom tsawg, ua kom lub cev tsim nyog, kho lub cev nyhav dhau los, tswj lub xeev kev xav, ua raws li kev pw tsaug zog thiab so).

Tus kws kho mob endocrinologist muab tshuaj, suav kev kho mob mus rau hauv tus account noj haus, lub hnub nyoog neeg mob, theem ntawm tus kabmob, concomitant pathologies, kev noj qab nyob zoo thiab lub cev kev teb rau cov tshuaj. Cov koob tshuaj yog txiav txim siab raws li glycemic profile ntawm tus neeg mob.

Qhov pib txhaj tshuaj yog ib txwm muaj raws li qhov tsawg kawg - ib nrab ib ntsiav tshuaj hnyav 5 mg lossis 3.5 mg ib hnub. Kev saib xyuas tshwj xeeb hauv kev kho mob koob tshuaj yog muab rau cov neeg mob asthenic nrog kev noj zaub mov rau lub cev, nyob hauv keeb kwm ntawm qhov muaj kev tawm tsam hypoglycemic, zoo li rau cov neeg koom nrog kev ua haujlwm hnyav lub cev. Thawj lub limtiam ntawm glycemic tswj txhua hnub yog xav tau. Kev noj tshuaj titration yog ua raws li cov lus tim khawv ntawm lub ntsuas ntsuas thiab kev txiav txim siab ntawm tus kws kho mob.

Txoj kev kho mob ntawm Maninil yog kwv yees li 15 mg / hnub, uas yog 3 ntsiav tshuaj ntawm 5 mg lossis 5 ntsiav tshuaj ntawm 3.5 mg.

Thaum Maninil hloov lwm cov tshuaj rau hypoglycemic, lawv raug coj los ntawm kev pib siv. Tom qab tshem tawm cov kev siv tshuaj yav dhau los, cov lus qhia glucometer thiab cov txiaj ntsig ntawm kev txheeb xyuas cov zis ntawm lub keeb kwm yav dhau los, tsis muaj tshuaj yeeb tshuaj, tau hais meej. Kev tawm tsam ntawm lub cev yog tshawb xyuas los ntawm qhov muaj pes tsawg kawg - 0.5 ntsiav tshuaj ntawm 3.5 lossis 5 mg. Ua raws li kev noj haus thiab lwm yam mob ntawm lub neej noj qab nyob zoo yog qhov yuav tsum tau ua. Txhawm rau kom tsis txhob muaj kev phiv, qhov koob tshuaj ntawm cov tshuaj tshiab yog nce ntau zuj zus. Tus mob ntshav qab zib yuav tsum qhia rau tus kws kho mob uas tau mus kawm txog txhua yam hloov pauv hauv kev noj qab haus huv.

Kev pom zoo rau kev siv

Maninil pom zoo kom siv nws thaum sawv ntxov, ua ntej noj tshais, ntxuav koj cov koob tshuaj ntawm lub khob nrog ib khob dej dawb. Thaum qhov kev cai ntau tshaj 2 pcs / hnub, nws muab faib ua 2 koob tshuaj hauv qhov sib piv ntawm 2: 1. Txhawm rau kom tau txais qhov kho mob siab tshaj plaws, nws raug nquahu kom noj cov tshuaj nyob rau tib lub sijhawm.

Sab sij huam

Raws li cov lus pom zoo los ntawm WHO, lub sijhawm dhau los ntawm kev cuam tshuam tsis zoo los ntawm cov tshuaj raug soj ntsuam rau ntawm qhov ntsuas tshwj xeeb:

• Ntau zaus - los ntawm 10%,
• Feem ntau - txij li 1 txog 10%,
• Qee zaum - los ntawm 0.1 txog 1%,
• Tsis tshua muaj - los ntawm 0.01% rau 0.1%,
• Tsis tshua muaj heev - txog 0.01% lossis cov neeg mob tsis tau sau cia txhua.

Cov xwm txheej ntawm qhov xwm txheej tsis zoo ntawm kev noj Maninil yog yooj yim kawm hauv lub rooj.

Pom kev tsis sib haum yog feem ntau pom thaum lub sijhawm hloov mus rau tshuaj thiab ploj mus ntawm lawv tus kheej, tsis muaj kev cuam tshuam kev kho mob. Dyspeptic cuam tshuam nyob rau hauv daim ntawv ntawm kev tawm tsam ntawm xeev ntuav, ntuav, raws plab tsis tas yuav hloov cov tshuaj thiab kuj ploj nthawv lub sij hawm.

Yog tias muaj hyperergic yam kev tsis haum rau glibenclamide, muaj kev pheej hmoo ntawm cholestasis intracranial nrog rau cov teeb meem mob hauv daim ntawv ua rau lub siab ua haujlwm tsis zoo.

Cov tawv nqaij ua xua feem ntau yog qhov thim rov qab, tab sis, qee zaus muaj peev xwm ua rau muaj kev poob siab uas yuav tsim teeb meem rau lub neej cov ntshav qab zib.

Los ntawm Maninil, kev ua xua thiab lwm yam kev phiv tuaj yeem pom los ntawm ua daus no, kub taub hau, cov tsos mob ntawm daj ntseg, kuaj pom cov protein hauv cov zis. Hauv txhua qhov xwm txheej, kev sab laj ntawm tus kws kho mob uas xav tau yog qhov tseem ceeb.

Hauv qee kis, kev txo qis hauv txhua cov ntshav cov ntshav tau muab sau tseg tam sim ntawd. Thaum cov tshuaj raug muab tso tseg, qhov xwm txheej tsis dhau nthawv. Kev phiv khaub thuas muaj peev xwm ua tau nrog lwm cov tshuaj uas ua rau mob lub siab nyob hauv tus neeg mob. Hauv tshwj xeeb, zas xim E124, uas yog siv rau hauv kev tsim cov tshuaj, yog qhov muaj hwj chim tsis haum.

Maninil - contraindications

Cov tshuaj tsis yog siv rau qhov ua kom txo qis mus rau qhov sib xyaw ntawm cov mis. Thiab, nws tsis pom tias:

• Rau kev fab tshuaj rau diuretics thiab ib qho tshuaj sulfonylurea-raws li, sulfonylamide npaj, probenecid,
• Tus mob ntshav qab zib nrog hom ntshav qab zib hom 1, nrog atrophy ntawm β-hlwb,
• Yog tias tus neeg mob tau tus kabmob metabolic acidosis, mob ntshav qab zib tsis xeev,
• Cov poj niam cev xeeb tub thiab lactating
• Cov neeg mob uas muaj mob rau daim siab thiab lub raum tsis ua haujlwm (qib 3),
• Cov neeg quav dej cawv thiab quav cawv (hem ua rau ntshav qog ntshav qab zib).

Nrog kev haus dej cawv ua rau lub ntsej muag, qhov ua kom lub ntsej muag ntawm glibenclamide zoo tuaj, thiab lub xeev ntawm intoxication npog cov tsos mob ntawm tab tom yuav muaj kev puas tsuaj.

Nrog lub plab ua haujlwm, kev raug mob hnyav, kub hnyiab, noj ib qho tshuaj tiv thaiv kab mob ntshav qab zib raug txwv. Lawv hloov mus ib ntus nrog cov tshuaj insulin, uas tso cai rau koj kom yooj yim thiab ceev kho cov ntsiab lus ntawm cov suab thaj hauv cov ntshav.

Tsis muaj kev txwv kiag li ntawm kev tswj hwm kev thauj khoom thiab lwm yam khoom siv rau lub sijhawm ua kev kho mob nrog Maninil. Tab sis kev mob ntshav qab zib tsawg tuaj yeem cuam tshuam kev xav thiab kev xav, tshwj xeeb hauv kev sib koom ua ke nrog kev noj qab zib. Yog li, cov qib ntawm kev pheej hmoo rau txhua tus mob ntshav qab zib yuav tsum ntsuas nws tus kheej.

Qhia Txog Tshuaj Yeeb

Nyob rau hauv cov kev kho kom zoo ib yam nrog glibenclamide thiab clonidine, thiab ntxiv rau β-adrenergic blockers, reserpine, guanethidine, cov tsos mob ntawm kev mob ntshav qab zib tsis muaj qhov ntsej muag thiab tsis pub ua kom tsis nco qab txog ntshav qab zib tsis nco qab yuav raug lees paub.

Kev siv cov tshuaj tso quav tsis tu ncua uas ua rau muaj qhov tsis zoo ntawm cov quav ua rau lub ntsej muag nyob hauv lub siab thiab ua rau muaj kev pheej hmoo ntawm hypoglycemia.

Ua kom muaj peev xwm ntawm glibenclamide txog kev tawm tsam hypoglycemic, koj tuaj yeem siv cov tshuaj tua kab mob tib yam li cov tshuaj insulin, ACE inhibitors, txo qis cov ntsiav tshuaj, tshuaj raws li txiv neej cov tshuaj hormones, tshuaj steroid, tshuaj tiv thaiv kab mob, β-blockers, clofibrate, tshuaj raws quinolone, coumarin, phenamine, disaminophen miconazole, PASK, pentoxifylline, perhexylin, pyrazolone, probenecid, salicylates, sulfonamidamide tshuaj, tshuaj tua kab mob ntawm chav kawm tetracycline, tritokvalin, cytost lub suab qw.

Nws inhibits qhov kev ua ntawm cov tshuaj, ua rau cov neeg muaj mob hyperglycemic, tib lub sijhawm siv ntawm acetazolamides, β-adrenergic thaiv cov tshuaj tiv thaiv, diazoxide, glucagon, barbiturates, diuretics, tubazide, glucocorticosteroids, phenothiazine chav tshuaj, phenytoin, nicotinates, cov tshuaj tua kab mob pawg, rifampicin pab pawg, tshuaj noj poj niam, sympathim lub qog ua haujlwm.

Coumarin pab pawg tshuaj, ranitidine, pais plab H2 receptor antagonists, pentamidine, reserpine ua kev tsis txaus ntseeg, ua yeeb yam xws li catalysts lossis inhibitors ntawm glibenclamide kev ua si.

Pab nrog overdose

Kev noj tshuaj ntau dua ntawm glibenclamide (ob qho tib si hauv cov qauv mob thiab kev ua kom tsis txaus siab) muab cov ntshav qog ntshav siab - muaj qhov cuam tshuam ntev, mob hnyav thiab ua rau tuag taus ntawm tus neeg raug mob. Cov kab mob kev soj ntsuam ntawm kev tawm tsam hypoglycemic, txhua tus mob ntshav qab zib yuav tsum paub kom raug:

• Tswj tsis tau kev tshaib plab
• Hleev ntawm caj npab thiab txhais ceg,
• Tachycardia
• Ua kom muaj kev ntxhov siab ntau dua
• Tawv tawv nqaij thiab qog ua kua.

Qee lub sij hawm muaj kev cuam tshuam ib ntus ntawm kev nco qab, paresthesia. Yog hais tias tus neeg raug tsim txom tsis tau txais kev kho mob thaum maj nrawm, nws poob rau hauv lub ntsej muag hypoglycemic precoma thiab coma, uas ua rau tuag tau.

Kev kuaj pom ntawm cov kev rau txim tom qab ntawd yog pib ntawm kev sau cov ntaub ntawv hais txog tus raug mob los ntawm cov txheeb ze paub txog cov tshuaj uas tus kab mob ntshav qab zib thiab nws muaj feem cuam noj. Ib lub chaw kuaj sim tshuaj yog nqa tawm.

Kev kuaj xyuas ntawm tus neeg raug mob tso cai rau koj soj ntsuam cov xwm txheej ntawm daim tawv nqaij (txias, txias, ntub). Qhov kub ntawv yuav zoo li qub lossis qis dua. Ua raws li qhov mob hnyav ntawm kev tawm tsam, cov leeg txhaws ntawm lub tonic lossis clonic yam, tsis kho raws kev cai, thiab pom tus mob chua leeg.

Yog hais tias tus neeg mob tseem nco qab, nws tuaj yeem haus dej qab zib nrog cov piam thaj tsis tu ncua, noj tej zaub mov carbohydrates sai sai (khoom qab zib, ncuav qab zib). Yog tias tus mob tseem tsis hloov, cov ntshav qab zib tau pw hauv tsev kho mob.
Nrog rau kev tsis nco qab nyob hauv tsev kho mob, ib qho 40% piam thaj tov (40 ml) yog muab rau iv. Raws li kev saib xyuas ntawm kev sim hauv chaw sim, kev kho txoj kev lis ntshav nrog kev pab ntawm molecular phaus lub cev hnyav yog kho tau.

Cov kab mob hypoglycemic ncua ntev thiab ncua kev tawm tsam raug paub, ua rau muaj kev npau suav ntawm glibenclamide. Cov xwm txheej zoo li no yuav tsum tau soj ntsuam cov neeg raug tsim txom hauv tsev kho mob li 10 hnub lossis ntau dua hnub nrog kev tshuaj xyuas glycemia thiab kho cov tsos mob kom zoo.

Yog tias tus neeg raug tsim txom noj tshuaj ib zaug thiab huam yuaj, nws txaus los yaug lub plab, muab tus neeg nqus thiab ib khob dej qab zib lossis kua txiv.

Analogues ntawm cov tshuaj

Nrog tib yam kev cuam tshuam ntawm Glibenclamide, Glibenclamide thiab Glibamide tuaj yeem hloov Maninyl. Kev taw qhia, contraindications, phiv yog zoo tib yam. Raws li ATX code ntawm qib 4 rau Maninil, Glidiab, Glyclazide, Diabeton, Glurenorm, uas muaj cov kev kho mob zoo sib xws, tuaj yeem siv analogues.

Cov lus pom zoo ntxiv

Rau cov neeg mob paub tab, cov neeg uas muaj zaub mov noj tsis txaus, asthenics, ntshav qab zib nrog concomitant mob siab thiab lub raum pathologies, qhov pib ntawm Maninil yog txo qis mus rau qhov tsawg kawg vim kev pheej hmoo ntawm hypoglycemia. Yog hais tias tus mob ntshav qab zib tau hloov pauv, kev ua neej, kev kho mob kuj tseem tau tshuaj xyuas.

Ua tib zoo saib xyuas rau cov neeg mob senile dementia, kev puas siab puas ntsws thiab lwm yam mob uas cuam tshuam txoj kev sib cuag tag nrho ntawm tus neeg mob nrog kws kho mob. Kuaj hauv chav kuaj ntawm cov neeg mob no yuav tsum ua kom ntau li ntau tau. Txheeb xyuas txhua qhov tshwj xeeb ntawm cov nyhuv ntawm cov tshuaj ntawm lub cev, lawv tau qhia txog cov tshuaj analogues nrog kev tso tawm sai ntawm cov tshuaj yeeb dej caw.

Yog hais tias tus mob ntshav qab zib tsis nqus metformin, nws tau raug muab tshuaj kho mob glitazone xws li rosiglitazone lossis pioglitazone. Nrog rau cov cim qhia tau tsim nyog, Maninil ntsiav tshuaj kuj tseem ntxiv nrog lwm cov tshuaj tiv thaiv kab mob ntshav nrog tshuaj sib txawv ntawm kev ua. Guarem lossis Acarbose, uas, zoo li Maninil, txhawb nqa lub txiav, tsis siv hauv kev kho mob nyuaj.

Kev siv lub sijhawm ntev ntawm glibenclamide depletes cells-hlwb, ua rau necrosis, thiab txhim kho qhov tsis zoo rau Maninil. Txhawm rau pab txhawb nqa tus txiav, ntshav qab zib tau pauv mus rau insulin (tag nrho lossis ib feem, nyob ntawm seb qhov degree ntawm lawv atrophy).

Kev ntsuas tshuaj ntawm cov kws kho mob thiab cov ntshav qab zib

Txog Maninil cov tshuaj xyuas tau sib xyaw. Cov kws kho mob cim nws raws li ib txwm noj tshuaj hypoglycemic nrog cov pov thawj muaj zog ntawm kev ua haujlwm thiab kev nyab xeeb. Cov neeg mob ntshav qab zib tsis txaus siab rau ib qho ntxiv yuav luag lees paub qhov hnyav nce thiab lwm cov kev mob tshwm sim, tab sis txhawm rau soj ntsuam qhov muaj peev xwm ntawm cov tshuaj raws li kev soj ntsuam ntawm ib tus neeg mob tshwj xeeb yog tsawg.

Cov lus pom zoo ntawm lub xaib no yog kev hloov kho ntawm cov lus qhia ntawm nom tswv, npaj rau kev paub dav dav, thiab tsis yog rau kev siv tus kheej. Cov kev xaiv ntawm cov tshuaj thiab kev npaj ntawm kev kho cov tshuaj yog tsuas yog lub luag haujlwm ntawm tus kws kho mob.

Kev piav qhia Maninil thiab kev taw qhia rau kev siv

Maninil yog kev kho rau hom 2 uas tsis muaj tshuaj insulin muaj ntshav qab zib mellitus. Nws yog lub ntsiav tshuaj paj yeeb rau kev tswj hwm qhov ncauj.

Qhov kev txiav txim ntawm cov tshuaj yog raws li kev tsim tawm ntawm kev tsim cov tshuaj insulin los ntawm tus txiav thiab nce ntxiv ntawm qhov rhiab heev rau nws. Raws li qhov tshwm sim, cov kua dej tawm ntxiv thiab nws cov nyhuv raug kho dua. Cov tshuaj noj tshuaj tiv thaiv glycogenolysis (kev rhuav tshem ntawm glycogen rau piam thaj) thiab gluconeogenesis (hluavtaws suab thaj los ntawm cov ntsiab lus tsis-carbohydrate) hauv lub siab. Qhov no tso cai rau koj kom ua tiav cov ntshav qabzib kom tsawg.

Maninil txo cov kev pheej hmoo txaus ntshai ntawm cov mob ntshav qab zib hom 2 - kev puas tsuaj rau cov hlab ntsha hlwb, lub zeem muag, lub plawv, cov hlab ntsha.

Sau ntawv tshuaj rau hauv qhov kis thaum poob phaus, kev noj zaub mov zoo thiab kev tawm dag zog tsis tau rov qab ua cov metabolism hauv lub cev.

Maninil ua rau cov ntshav qab zib ntawm lub cev qib siab

Cov tshuaj yuav tsum tau sau tseg los ntawm tus kws endocrinologist. Tsuas noj yog txiav txim tau tom qab kuaj xyuas thiab kuaj cov ntshav qab zib thiab cov zis thiab tuaj yeem hloov kho lub sijhawm.

Tso tawm daim ntawv thiab muaj pes tsawg leeg

Cov tshuaj nquag muaj tshuaj yog micronized glibenclamide.

Ib ntsiav tshuaj ntawm Maninil muaj los ntawm 1.75 txog 5 mg ntawm glibenclamide.

Vim tias cov ntawv sib txawv ntawm kev tso tawm, nws yog qhov yooj yim rau xaiv cov tshuaj uas yog qhov zoo rau txhua theem ntawm kev kho mob. Ntawm kev muag koj tuaj yeem nrhiav cov khoom ntim hauv qab no:

• 1.75 mg - 120 pcs. (120 rub.),
• 3.5 mg - 120 pcs. (160 rub.),
• 5 mg - 120 pcs. (135 rub.)

Cov kev tshem tawm hauv qab no tam sim no hauv cov ntsiav tshuaj nrog tshuaj ntau npaum 1.75 mg thiab 3.5 mg:

• lactose monohydrate,
• cov hmoov txhuv nplej siab
• methyl hydroxyethyl cellulose,
• colloidal silicon dioxide,
• magnesium stearate,
• zas (E124).

5 mg ntsiav tshuaj muaj daim ntawv sib txawv me ntsis ntawm tus tshaj lij:

• lactose monohydrate,
• magnesium stearate,
• cov hmoov txhuv nplej siab
• zas (E124),
• talcum hmoov
• nkaws.

Cov Yuav Tsum Muaj

Maninil yog qhov sib txawv hauv cov teeb meem hauv qab no:

• ntshav qab zib hom 1
• rhiab rau ib qho ntawm cov khoom siv
• mob siab thiab mob raum,
• ob leeg plob tsis so tswj,
• hypoglycemic coma thiab precoma,
• kev phais plab plab
• paresis ntawm lub plab
• ketoacidosis.

Lub cuab yeej siv tsis tau yog cov poj niam cev xeeb tub thiab cov neeg muaj menyuam tsis taus, cov menyuam yaus thiab cov neeg hluas hnub nyoog qis dua 18 xyoo. Maninil tseem ua rau cov neeg muaj cawv quav yeeb quav cawv ua ke.

Nrog rau kev tswj hwm tib lub sijhawm ntawm Maninil nrog cawv, muaj kev txaus ntshai tuaj yeem tshwm sim hauv daim ntawv ntawm hypoglycemia (ib qho poob hauv qab zib).

Muaj cov tshuaj tsis haum thiab noj tshaj

Yog tias noj tsis raug, Maninil tuaj yeem ua rau cov ntshav qab zib tsawg, tshwj xeeb tshaj yog tias muaj ntau tshaj lossis yuam kev ntawm cov tshuaj, nrog rau kev haus cawv. Txoj kev pheej hmoo nce nrog kev txav tawm ntawm lub cev tam sim, kev tshaib plab, cov metabolism hauv lub cev tsis hnov ​​lus (nrog cov teeb meem endocrine).

Nyob rau theem pib ntawm kev kho, qhov muag pom kev tsis zoo lossis nce siab ntawm lub teeb pom kev zoo yuav tshwm sim. Tus txheej txheem no thim rov qab thiab sijhawm dhau los txhua yam yuav rov qab ua qhov qub.

Cov kev tsis zoo tshwm sim los ntawm txoj hnyuv plab feem ntau tsis tshua pom:

Muaj qee kis tshwj tsis yog cov teeb meem tshwm sim ntsig txog kev tsim cov ntshav (ntshav sib hloov ua ke).

Yuav kom txo qis cov kev pheej hmoo txaus ntshai, kev kho mob ntshav qab zib nrog Maninil yuav tsum tau ua nyob rau hauv kev saib xyuas ntawm tus neeg mob endocrinologist.

Kev tswj hwm ncua ntev ntawm Maninil tej zaum yuav ua rau lub luag haujlwm txo qis cov qog thiab nce ntxiv hauv lub cev.

Yog tias koj noj tshuaj ntau dhau ntawm Maninil, kev tiv thaiv hypoclycemia pheej muaj peev xwm raug kuaj pom. Nws yog tus cwj pwm los ntawm txoj kev xav zoo nkaus li kev tshaib kev nqhis, ntxhov siab, palpitations, pallor ntawm daim tawv nqaij. Yog tias tsis ua raws li kev ntsuas tsim nyog, tsaus muag thiab tsis nco qab tuaj yeem tshwm sim, fraught nrog kev tuag ntawm tus neeg mob. Cov txheej txheem ntawm kev nqis tes ua hauv cov xwm txheej nyuaj yog qhov zoo dua los tham nrog tus kws kho mob ua ntej.

Ua tib zoo mloog! Ib cov tshuaj overdose yog qhov txaus ntshai heev. Tsim txoj kev noj tshuaj txhua hnub yuav tsum tsuas yog tus kws tshaj lij ntawm cov khoom siv ntawm kev tshuaj ntsuam. Kev noj tshuaj rau tus kheej tsis tuaj yeem lees txais.

Nkag Tawm Cov Cai

Tsis zoo li qee cov tshuaj hypoglycemic, Maninil yuav tsum tau noj thaum sawv ntxov ntawm lub plab khoob. Tag nrho cov ntsiav tshuaj muab ntxuav tag nrog lub khob dej. Yog tias tus kws kho mob pom zoo kom faib cov koob tshuaj rau hauv ob lub tshuaj, tom qab ntawv thib ob qhov no yuav tsum tau ua rau thaum yav tsaus ntuj, tab sis tseem ua ntej noj mov.

Tseem Ceeb! Yuav kom ua tiav cov txiaj ntsig zoo, koj yuav tsum haus cov tshuaj nyob rau tib lub sijhawm txhua hnub. Nws tsis tsim nyog mus hla kev ua kom yuam kev.

Vim tias muaj kev sib txawv hauv kev tso tawm, hauv kev kho mob niaj hnub muaj txog nees nkaum qhov qauv rau kev siv Maninil. Lub sijhawm tiv thaiv kev kho mob yog txiav txim los ntawm tus kws kho mob endocrinologist raws li kev mob ntawm tus neeg mob tshwj xeeb. Thaum txoj kev kho, kev saib xyuas txhua lub lim tiam ntawm cov ntshav piam thaj hauv cov ntshav thiab zis yuav tsum tau ua.

Ua tib zoo mloog! Yog tias kev noj zaub mov kom plooj lossis qib qoj ib ce hloov pauv, koj yuav tsum qhia koj tus kws kho mob. Qhov no yuav yog vim li cas rau kev kho qhov ntau ntawm cov tshuaj.

Maninil tuaj yeem siv nrog lwm cov kab mob hypoglycemic (insulin, metformin), tshuaj anabolic, ACE inhibitors, txiv neej cov tshuaj hormones. Nrog rau kev tswj fwm nrog rau lwm cov tshuaj, cov nyhuv ntawm Maninil tuaj yeem nce lossis tsawg dua. Qhov no yuav tsum tau txiav txim siab thaum txiav txim ntau npaum.

Yog tias tsis ua tiav nrog kev kho mob nrog Maninil lossis kev tsis txaus siab ntawm nws cov khoom siv rau kev kho mob ntshav qab zib hom 2, lwm cov tshuaj tuaj yeem xaiv. Muaj cov txheej txheem (los ntawm cov tshuaj yeeb dej caw) thiab tsis-tus yam ntxwv (los ntawm kev kho mob nyhuv) cov qauv ntawm cov tshuaj Maninil. Cia peb xav txog qee qhov ntawm lawv.

Kuv tuaj yeem hloov Maninil - rooj

Kev Ntsuam Xyuas Rau Neeg Mob

Cov tshuaj no raug sau tseg rau cov neeg mob ntshav qab zib hom 2. Cov tshuaj no tau sau los ntawm tus kws kho mob rau peb cov pog. Peb tau txais nws hauv lub tsev muag tshuaj rau qhov nyiam cov zaub mov txawv. Tus nqi ntawm cov tshuaj no yog 164 rubles. Nws yuav tsum tau ceev faj nrog, raws li tus kws kho mob qhia. Thaum lub sijhawm txais tos, nws yog qhov tsim nyog los tswj cov theem ntawm cov piam thaj hauv cov ntshav. Noj khoom raws sijhawm, txwv tsis pub hypoglycemia yuav pib ua haujlwm. Peb tus pog no tau noj cov tshuaj no tau ob lub hlis tam sim no. Nws xav tias zoo heev, nyob puv neej. Cov tshuaj muaj txiaj ntsig zoo, zoo tag nrho nrog nws txoj haujlwm.

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Cov menyuam ntxhais, kuv, ib yam nkaus, nrog koj - Kuv muaj ntshav qab zib ib yam: poob ceeb thawj - qab zib nce mus txog ib txwm, ntxiv nws - nws nkag siab. Kuv lub siab yeej ib txwm npog kuv lub qhov muag thaum peb peb (nrog kuv, nrog nws thiab ntshav qab zib) pib noj. Nov peb rhuav. Tam sim no kuv rov rub kuv tus kheej ua ke - thiab rov pov ib zaug me ntsis. Kuv noj tshuaj Maninil 3.5 - 1 ntsiav tshuaj ua ntej noj mov thiab Glucofage 500 qhov kawg ntawm pluas noj thaum sawv ntxov thiab yav tsaus ntuj. Kuv xav tias kuv tus mob zoo: txawm tias kuv tuaj yeem txiav txim siab kuv qab zib yuav luag zoo.

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Thiab kuv nyiam Maninil, qhov txaus ntshai heev thiab qhov tshwm sim uas xav tau, tab sis, raws li lawv hais, rau txhua tus nws tus kheej.

Androlik500

Yuav ua kom txoj kev kho mob ntshav qab zib ua tau zoo, koj yuav tsum ua raws li cov lus pom zoo. Cov tshuaj ntawm Maninil yog txiav txim los ntawm tus kws kho mob raws li kev soj ntsuam ntawm kev tshawb fawb. Thaum lub sij hawm kho nrog tshuaj, nws yog ib qho tsim nyog yuav tsum tau ntsuas cov piam thaj tsis tu ncua thiab txwv tsis pub haus dej haus cawv.

Ntxiv txog ntshav qab zib:

Thaum sawv ntxov thiab yav tav su tom qab noj mov, Kuv noj ib qho thiab ib nrab ntsiav tshuaj ntawm maninil 3.5 m / g, i.e. 10,5 m / g nyob rau ib hnub. Kuv noj txhua yam, i.e. Kuv noj khoom qab zib ib yam nkaus. Kuv kuaj kuv cov ntshav qab zib thaum sawv ntxov rau qhov khoob ntawm lub plab. Nrog kev noj haus zoo thiab kev kho mob, cov ntshav qab zib cov ntshav tsis siab tshaj 6,5 m / mol. Cov cim ntawm ntshav qab zib tsis ua raws li - hnyav ntxiv, khaus, tso zis ntau zaus, tsis muaj zog, nqhis dej. Nws tsim txoj kev txiav txim no rau nws tus kheej. Kuv paub tias qhov kev txiav txim tsis raug thiab kuv tej zaum noj ntau dhau manila. Qhia rau kuv yuav ua li cas.

Kev faib tawm (cov npe) ntawm cov tshuaj muaj ntshav qab zib rau hom ntshav qab zib hom 2

Txij li thaum muaj ntau cov tshuaj los txo cov ntshav qab zib, Kuv txiav txim siab los qhia koj rau lawv ua ntej. Muaj cai nrog txhua tus neeg hauv tsab xov xwm no. Rau koj kom yooj yim, kuv yuav qhia hauv kab ntawv rau cov lag luam nrov tshaj plaws, tab sis nco ntsoov tias muaj ntau ntxiv. Yog li lawv nyob ntawm no:

1. Pab pawg neeg loj (uanuan) thiab nws tus sawv cev yog metformin (siofor).
2. Pab pawg neeg sulfonylurea thiab nws cov neeg sawv cev yog glibenclamide (maninyl), glyclazide (ntshav qab zib mv 30 thiab 60 mg), glimepiride (amaryl), glycidone (glurenorm), glipizide (minidiab).
3. Cov pab pawg hauv pawg thiab nws tus neeg sawv cev tsuas yog repaglinide (novonorm).
4. Cov thiazolidinedione pab pawg thiab nws cov sawv cev yog rosiglitazone (avandium) thiab pioglitazone (actos).
5. Cov pab pawg ntawm alpha-glucosidase inhibitors thiab nws tus sawv cev yog acarbose (glucobai).
6. Pab pawg ntawm dipeptidyl peptidase-4 inhibitors (DPP-4) thiab nws cov sawv cev yog vildagliptin (galvus), sitagliptin (Januvia), saxagliptin (onglise).
7. Cov pab pawg ntawm glucone-zoo li peptide-1 agonists (GLP-1) thiab nws cov neeg sawv cev yog exenatide (byeta), liraglutide (yeej).
8. Dab neeg Pawg ntawm cov tshuaj tiv thaiv ntawm sodium-glucose-cotransporter hom 2 inhibitors (SGLT2 inhibitors) - dapagliflozin (Forsig), canagliflozin (Invokana), empagliflosin (Jardians)

Biguanide cov ntshav txo cov tshuaj

Pab pawg neeg lojuanide sawv khov kho ntawm cov podium ntawm txhua yam tshuaj muaj suab thaj rau cov ntshav qab zib hom 2.

Tus sawv cev tsuas yog metformin. Cov tshuaj los ntawm cov pab pawg no muaj qhov ua kom zoo ib yam, txo cov tshuaj insulin. Tab sis, raws li nws tig mus, lawv muaj ntau lwm cov txiaj ntsig zoo, piv txwv li, nws yog siv los txo qhov hnyav thiab poob ceeb thawj.

Hauv nws tsab xov xwm "Metformin - cov lus qhia rau siv" Kuv tsis tsuas yog piav qhia nyob rau hauv kev nthuav dav zoo rau cov tshuaj no kom txo qis ntawm cov piam thaj hauv cov ntshav ntawm cov ntshav qab zib, tab sis kuj tau tshaj tawm cov npe kev lag luam tawm thiab cov duab sib piv.

Thiab hauv kab lus "Metformin rau kom poob phaus: txhua qhov zoo thiab tsis pom zoo" Kuv sau txog kev siv tshuaj rau qhov hnyav tsis txaus.

Cov tshuaj ntshav qab zib los ntawm cov pawg sulfonylurea

Cov tshuaj ntshav qab zib los ntawm cov pawg sulfonylurea. Qhov no yog ib pab pawg loj heev, uas kuj tau tsim tawm ntev dhau los. nyob rau hauv lawv muaj pes tsawg leeg lawv muaj ob qho tib si cov tshuaj ntsuab qub raws li glibenclamide (maninyl), ntawm tiam tshiab, zoo li glimepiride (amaryl).

Cov piam thaj hauv cov ntsiav tshuaj raws li sulfanylurea muaj cov nyhuv ntawm cov txiav ua ke thiab tsis tas li rau cov neeg mob ntshav qab zib nrog hom thib ob.

Tam sim no muaj tsuas yog ib tsab xov xwm "Mob ntshav qab zib mv 30 thiab 60 mg hauv kev kho mob ntshav qab zib", tab sis tsis ntev yuav muaj ntawv tshaj tawm rau lwm tus neeg sawv cev, yog li kuv xav kom koj sau npe yuav cov ntawv tshiab kom tsis txhob muaj cov ntaub ntawv luam tawm.

Alpha glucosidase inhibitors - ntsiav tshuaj nrog piam thaj siab

Tus sawv cev los ntawm pawg alpha-glucosidase inhibitors - plab hnyuv plab - txwv qhov nqus ntawm carbohydrates thiab yog li txo cov ntshav qab zib.

Tus sawv cev tsuas yog acarbose (Glucobay). Nws tsis yog lub ntsiab ntawm qhov ncauj tshuaj rau mob ntshav qab zib hom 2, tab sis theej tus pab, vim tias nws tsis muaj suab thaj txo cov nyhuv.

Acarbose feem ntau ua ke nrog lwm cov tshuaj. Nyeem txog cov tshuaj no uas txo cov ntshav qab zib hauv tsab xov xwm "Acarbose thiab txhua yam txog nws."

Nov yog txhua yam kuv xav hais rau koj rau hnub no. Hauv kuv tsab xov xwm tom ntej no, kuv yuav txuas ntxiv zaj dab neeg txog qhov piam thaj txo cov tshuaj ntawm sulfonylurea pab pawg thiab lwm pab pawg. Yog tias koj muaj lus nug lossis ntxiv, thov hais hauv cov lus. Thiab ntawm qhov no kuv hais zoo rau koj. Bye!