Ofloxin - cov lus qhia rau kev siv, muaj pes tsawg leeg, tso tawm daim ntawv, ntau npaum li cas, ua piv txwv thiab tus nqi

• Cov yeeb yaj kiab xim-ua yeeb yaj kiab: yuav luag dawb lossis dawb, puag ncig biconvex, sau nrog "200" ntawm ib sab thiab faib cov cim ntawm lwm tus, cov qauv sab hauv lub sijhawm so yog dawb lossis yuav luag dawb (hauv cov hlwv: 7 pcs., Ib cardboard pob 2 blisters, 10 pcs., hauv daim thawv ntawv 1 los yog 2 hlwv),
• Kev daws rau Txoj kev lis ntshav: lub ntshiab, lub teeb ua kua nrog lub xim daj-ntsuab zas (100 ml hauv lub khob tsis muaj kob, 1 lub raj mis hauv ib pob ntawv).

Lub thawv ntawv thawv kuj tseem muaj cov lus qhia rau kev siv Ofloxin.

Cov khoom xyaw dhia - ofloxacin:

• 1 ntsiav tshuaj - 0.2 g
• 1 lub raj mis ntawm kev daws - 0.2 g.

• Ntsiav tshuaj: povidone 25, lactose monohydrate, crospovidone, pob kws hmoov txhuv nplej siab, magnesium stearate, poloxamer, talc,
• Tshuaj: disodium edetate dihydrate, concentrated hydrochloric acid, sodium chloride, dej rau kev txhaj tshuaj.

Tsis tas li ntawd, nyob rau hauv muaj pes tsawg leeg ntawm lub plhaub ntsiav tshuaj: macrogol 6000, hypromellose 2910/5, titanium dioxide, talc.

Cov Tshuaj Hauv Tshuaj

Ofloxin cov tshuaj nquag, ofloxacin, yog cov tshuaj tiv thaiv kab mob uas muaj ntau yam nrog cov kab mob bactericidal ua tau zoo. Cov neeg koom nrog pab pawg ntawm fluoroquinolones. Lub tshuab ntawm nws cov kev ua yog vim muaj peev xwm los thaiv DNA gyrase ntawm cov kab mob me me - ib qho enzyme uas koom nrog hauv cov txheej txheem ntawm kev hloov pauv thiab rov ua cov deoxyribonucleic acid (DNA) cov kab mob.

Ofloxacin muaj cov tshuaj tiv thaiv kab mob tawm tsam gram-zoo thiab gram-tsis zoo, xws li Proteus spp., Enterobacteriaceae (Citrobacter spp., Enterobacter spp., Escherichia coli, Klebsiella spp., Providencia spp., Salmonella spp., Shigella spp. Yersinia spp.). Nws yog zoo tiv thaiv kab mob tshwm sim los ntawm cov nram qab no cov kab mob: Acinetobacter spp, Branhamella catarrhalis, Brucella melitensis, Campylobacter spp, Gardnerella vaginalis, Haemophilus influenzae, Haemophilus ducreyi, Helicobacter pylori, Neisseria meningitidis, Neisseria gonorrhoeae, Pasteurella multocida, Pseudomonas aeruginosa, Pseudomonas spp, ... Vibrio spp.

Ofloxin kuj tseem nyob hauv staphylococci, suav nrog rau cov neeg ua paug rau penicillinase thiab methicillin tiv thaiv kab mob ntawm ntau yam kab mob (Chlamydia trachomatis, Chlamydia pneumoniae, Mycobacterium tuberculosis, Mycobacterium leprae, Mycoplasma pneumoniae, Ureaplasma urealy).

Ofloxacin muaj kev txwv tsawg rau kev tiv thaiv kev sib kis los ntawm pawg A, B thiab C. streptococci.

Anaerobes (tshwj tsis yog Clostridium perfringens) thiab tus neeg sawv cev ntawm cov mob syphilis tiv thaiv Ofloxin.

Cov Tshuaj Pharmacokinetics

Tom qab qhov ncauj tswj hwm ntawm Ofloxin, ofloxacin nrawm sai los ntawm kev mob plab zom mov. Qhov siab tshaj plaws hauv cov ntshav (Cmax) nce mus txog hauv 60-120 feeb.

Plasma protein khi 25%. Txoj kev ntawm bioavailability yog 96-100%. Nws nkag mus rau hauv cov ntaub so ntswg zoo, faib rau txhua qhov ntawm lub cev, suav nrog tus txha caj qaum. Hauv qhov siab, nws tau txiav txim siab hauv lub zais zis thiab lub zais zis. Nkag tau los ntawm thaj chaw tiv thaiv hniav dawb thiab hauv niam mis.

Nws yog metabolized rau ofloxacin-N-oxide thiab ofloxacin-desmethyl. Kev tshem tawm ib nrab-lub neej yog 5-8 teev, nws muaj peev xwm nce ntau ntxiv yog tias lub raum tsis ua haujlwm - txog li 15-60 teev. Kwv yees li 80% ntawm qhov tau txais yog raug tshem tawm los ntawm lub raum los ntawm tubular kev tso pa tawm thiab lim, uas tsis pub ntau tshaj 5% yog metabolites, tus so yog tsis hloov pauv tshuaj. Lwm 4–8% ntawm qhov koob tshuaj tau tawm ntawm txoj hnyuv. Kev nqig tau qeeb hauv cov neeg mob mob siab mob siab.

Kev tshem tawm tag nrho yog 214 ml / min, lub raum - 173 ml / min. Hauv cov khoom me me, nws yog tawm thaum lub sijhawm hemodialysis. Ib nrab-lub neej nyob rau lub sijhawm hemodialysis yog 8-12 teev, nrog peritoneal lim ntshav - 22 teev.

Tom qab kev tso ntshav tawm ntawm 200 mg ofloxine, Cmax ofloxacin pom tom qab kwv yees li 1 teev. Kev saib xyuas qhov sib luag ntawm cov tshuaj yog pom tom qab kev tswj hwm ntawm 4 infusions. Kev tshem tawm ib nrab-lub neej yog 6-7 teev.

Kev ntsuas rau siv

Kev siv Ofloxin yog qhia hauv kev kho mob kis mob thiab mob tshwm sim los ntawm cov kab mob me me rau cov tshuaj:

• Mob ntsws ntsws, ntsws txham,
• Ua mob rau daim tawv nqaij
• Mob Sinusitis, mob otitis, mob pharyngitis, laryngitis,
• Sib koom tes thiab pob txha mob
• Cov kab mob kis tau ntawm daim tawv nqaij, cov nqaij mos,
• Kev kis mob thiab mob ntawm txoj hnyuv, ua haujlwm ua ke thiab lwm yam plab hnyuv ntawm lub plab,
• Endometritis, oophoritis, salpingitis, cervicitis, prostatitis, parametritis,
• Pyelonephritis, cystitis, mob ruas,
• Gonorrhea
• Chaw mos (orchitis, colpitis, epididymitis),
• Chlamydia

Cov neeg mob neutropenia thiab lwm yam tsis muaj zog tiv thaiv kab mob Ofloxin yog raug kho rau kev tiv thaiv kev kis mob.

Tsis tas li ntawd, txoj kev daws teeb meem yog siv rau hauv kev kho mob ntawm septicemia.

Cov Yuav Tsum Muaj

• Qaug dab peg (suav nrog hauv keeb kwm),
• Cov piam thaj-6-phosphate dehydrogenase tsis txaus,
• Kev ua kom qis ntawm qhov pib ntawm kev ua rau lub hlwb muaj zog, suav nrog cov xwm txheej tom qab mob stroke, mob hlwb lossis raug mob rau hauv nruab nrab lub paj hlwb (CNS),
• Tsis txog 18 xyoo
• Lub caij muaj menyuam thiab kev pub niam mis,
• Hypersensitivity rau cov tshuaj.

Nrog kev ceev faj, Nws raug pom zoo tias Ofloxin raug kho rau cov neeg mob uas mob cerebral arteriosclerosis, qhov qhia txog keeb kwm ntawm cerebrovascular kev sib tsoo, organic kev puas tsuaj rau lub hauv nruab nrab lub paj hlwb, thiab mob raum tsis ua haujlwm.

Tsis tas li ntawd, Ofloxin ntsiav tshuaj yog contraindicated nyob rau hauv cov neeg mob uas muaj kev puas tsuaj rau cov leeg tom qab kev kho mob quinolone dhau los, thiab nrog ceev faj thaum ua ntev ntawm QT interval electrocardiography.

Zaj duab xis-coated ntsiav tshuaj

Ofloxin ntsiav tshuaj noj ua ntej noj mov lossis thaum noj mov, los ntawm qhov ncauj, nqos tag nrho thiab haus dej kom ntau.

Tus kws kho mob tau sau ntawv rau lub koob tshuaj thiab lub sijhawm ua haujlwm ntawm cov tshuaj raws li kev qhia soj ntsuam, suav txog qhov mob hnyav ntawm tus neeg mob, hom kabmob kis thiab lub luag haujlwm ntawm lub siab thiab lub raum.

Qhov pom zoo txhua hnub koob tshuaj Ofloxin tuaj yeem yog los ntawm 0.2 txog 0.6 g, yog li ib qho koob tshuaj ntau txog 0.4 g ib hnub twg noj 1 zaug, nyiam dua thaum sawv ntxov, thiab qhov koob tshuaj ntau dua 0.4 g tau muab faib ua ob sab sib luag thiab coj ntawm kev sib luag sib luag sij hawm 2 zaug ib hnub. Lub sijhawm kho yog 7-10 hnub.

Hauv cov ntawv hnyav ntawm cov kab mob sib kis lossis thaum tus neeg mob rog dhau, cov tshuaj txhua hnub yuav raug nce rau 0.8 g.

Hauv kev kho mob ntawm kev mob kis tsis yooj yim ntawm cov mob txeeb zig qis dua, 0.2 g ib hnub yog kho rau 3-5 hnub, muaj kab mob gonorrhea - 0.4 g ib zaug.

Kev kho mob thaum pib nrog Ofloxin ua ib qho kev daws teeb meem tom qab kev txhim kho ntawm tus neeg mob tuaj yeem txuas ntxiv los ntawm kev noj cov ntsiav tshuaj hauv tib lub tshuaj.

Kev siv qhov tseeb nrog antacids yog contraindicated.

Txoj kev lis ntshav daws

Ofloxin daws yog muab tshuaj ua leeg ntshav.

Cov koob tshuaj yog sau tseg ib leeg zuj zus, suav mus rau hauv qhov hnyav thiab hauv zos ntawm tus kab mob, qhov mob rhiab ntawm cov kab mob me me, qhov mob ntawm tus neeg mob, lub raum thiab lub siab ua haujlwm.

Kev kho mob pib nrog kev txhaj tshuaj ib zaug qeeb ntawm 0.2 g ntawm cov tshuaj rau 0.5-1 teev. Tom qab txhim kho tus neeg mob tus mob, lawv raug xa mus rau hauv cov ntsiav tshuaj hauv tib hnub.

Pom zoo Dosing Ofloxin:

• Cov mob txeeb zig: 0.1 g 1-2 zaug ib hnub,
• Kev kis mob ntawm qhov chaw mos thiab raum: 0.1-0.2 g 2 zaug ib hnub,
• Kev kis mob ntawm lub ntsws ua pa, pob ntseg, lub caj pas thiab lub qhov ntswg (pharyngitis, sinusitis, otitis media, laryngitis), cov nqaij mos thiab tawv nqaij, pob txha thiab pob qij txha, mob plab, septic kab mob: 0.2 g 2 zaug hauv ib hnub, kom ua tiav txoj kev kho mob, koob tshuaj tuaj yeem nce ntxiv rau 0.4 g 2 zaug ib hnub,
• Kev tiv thaiv ntawm kev kis kab mob nrog lub suab txo qis hauv kev tiv thaiv: 0.2 g, tov nrog 5% kua nplaum tov, lub sijhawm ntawm infusion - 0.5 teev (sib tov cov kev daws teeb meem tam sim ntawd ua ntej tswjhwm).

Ib koob tshuaj Ofloxin rau kev kho mob rau cov neeg mob uas lub raum ua haujlwm tsis zoo (kev tsim kho lub cev muaj peev txheej (CC) 50-20 ml / min) yuav tsum sib xws li 1/2 ntawm qhov nruab nrab pom zoo thiab thov 1-2 zaug hauv ib hnub. Nrog CC tsawg dua 20 ml / min, ib koob tshuaj ntawm 0.2 g yog tshuaj, tom qab ntawd - txhua lwm hnub, 0.1 g ib hnub.

Nrog rau cov mob hemodialysis thiab peritoneal lim ntshav - 0.1 g ib hnub ib zaug.

Rau cov neeg mob uas muaj daim siab tsis ua hauj lwm, koob tshuaj txhua hnub yuav tsum tsis pub ntau dua 0.4 g.

Sab sij huam

• Cov kab mob hauv lub cev: xeev siab, ntuav, mob pob qij txha, raws plab, mob plab, mob plab thiab lwm yam mob plab, pseudomembranous enterocolitis, nce kev ua haujlwm ntawm daim siab enzymes, cholestatic jaundice, hyperbilirubinemia,
• Kev mob plawv: txo cov ntshav siab (BP), vasculitis, tachycardia, vau,
• Lub cev tsis muaj zog: mob taub hau, cramps, tsis ruaj ntseg ntawm kev txav, kiv taub hau, tshee tshee, teeb tsa thiab tawv nqaij ntawm qhov kawg, ua rau muaj kev ntxhov siab ntau ntxiv, mob siab thiab / los yog npau suav npau suav, ntxhov siab vim, kev puas siab puas ntsws, phobias, nce siab kev npau taws, kev nyuaj siab, hnov ​​qab, tsis meej,
• Hematopoietic system: ua haujlwm ntshav liab, agranulocytosis, leukopenia, pancytopenia, thrombocytopenia, aplastic thiab hemolytic anemia,
• Hnov kabmob plab hnyuv siab raum: hnov ​​qhov tsis hnov ​​tsw tsw, hnov ​​qab, hnov ​​lus, sib npaug, sib npaug, daim ntawv pov thawj, lub ntsej muag xim tsis zoo,
• Musculoskeletal system: tendosynovnovitis, myalgia, leeg mob, mob caj dab, mob caj dab,
• Cov kab mob hauv lub raum: lub raum lub raum tsis ua haujlwm, ntshav urea siab ntxiv, mob ntshav txhaws, mob hypercreatininemia,
• Cov tshuaj tiv thaiv kab mob: petechiae (taw tes los ntshav), mob ntshav liab los yog nqaij tawv, tawv nqaij, tawv nqaij daj,
• Kev tsis haum tshuaj: ua npaws, khaus, ua pob rau ntawm daim tawv nqaij, urticaria, tshuaj tiv thaiv mob ntsws, eosinophilia, ua xua nephritis, Quincke's edema, Stevens-Johnson syndrome, bronchospasm, erythema multiforme, Lyell's syndrome, anaphylactic shock,
• Lwm yam: superinfection, dysbiosis, nrog ntshav qab zib - hypoglycemia, vaginitis.

Tsis tas li ntawd, Ofloxin tuaj yeem ua rau muaj kev phiv cov yam ntxwv ntawm ib qho ntawm cov tshuaj:

• Cov ntsiav tshuaj: los ntawm lub plab zom mov - kab mob siab, musculoskeletal system - cov leeg tsis muaj zog, rhabdomyolysis,
• Tshuaj rau txoj kev lis ntshav: cov tshuaj tiv thaiv nyob rau hauv qhov chaw txhaj tshuaj hauv daim ntawv ntawm qhov mob, liab, thrombophlebitis.

Cov lus qhia tshwj xeeb

Nrog rau kev mob ntsws txhaws mob ntsws thiab mob tonsillitis, Ofloxin tsis yog siv rau kev siv.

Lub sijhawm kho nrog cov tshuaj yuav tsum tsis pub ntau tshaj 2 hli.

Tus neeg mob yuav tsum zam kom txhob raug tshav ncaj qha thiab duab hluav taws xob.

Thaum cov tsos mob tshwm sim los ntawm lub hauv nruab nrab ntawm lub paj hlwb, pseudomembranous colitis, kev txhim kho kev ua xua tshwm sim, kev kho yuav tsum tau tsum tsis ua ntxiv. Txog kev kho mob rau kev kuaj ntshav kuaj kab mob pseudomembranous colitis, kev tswj hwm ntawm daim ntawv ntawm qhov ncauj ntawm vancomycin thiab metronidazole yog qhia.

Kev siv Ofloxin hauv qee qhov tsis tshua muaj tshwm sim ua rau kev txhim kho ntawm txoj leeg mob, uas tuaj yeem ua rau lub caj dab tawg (Achilles leeg), ntau zaus hauv cov neeg laus. Yog li no, thaum txoj kev sib thooj tshwm sim, nws yog qhov yuav tsum tau ua kom tsis muaj dab tsi hauv Achilles leeg thiab txais kev sab laj orthopedic.

Cov poj niam tsis pom zoo kom siv cov tampons ntawm lub paum thaum kho vim muaj kev pheej hmoo siab ntawm kev mob candidiasis.

Cov nyhuv ntawm Ofloxin tuaj yeem ua rau txoj kev tsis zoo ntawm myasthenia gravis, hauv cov neeg mob uas nquag muaj kabmob porphyria - ua rau muaj kev nce ntxiv ntawm qhov mob chua leeg, nrog kev kuaj mob bacteriological ntawm tuberculosis - muab cov txiaj ntsig tsis zoo.

Yog tias lub raum ua rau lub raum lossis lub cev tsis ua haujlwm zoo, yuav tsum saib xyuas txhua zaus ntawm qib ofloxacin hauv cov ntshav ntshav. Vim tias qhov phom sij muaj teeb meem, cov neeg mob uas lub raum loj thiab lub siab tsis txaus yuav tsum tau txhaj tshuaj.

Kev haus dej cawv thaum lub sijhawm kho nrog Ofloxin yog contraindicated.

Kev siv cov tshuaj daws teeb meem rau txoj kev kho mob hauv tsev menyuam yog ua tau tsuas yog thaum muaj kev hem thawj rau lub neej ntawm tus menyuam, thaum nws tsis tuaj yeem siv lwm yam, kev siv tshuaj lom tsawg, tom qab ua tib zoo ntsuas ntawm cov kev cia siab tias yuav muaj txiaj ntsig thiab muaj kev pheej hmoo ntawm kev phiv. Thaum sau tshuaj, qhov nruab nrab ib hnub twg pom zoo hauv qhov ntau npaum li ntawm 0.0075 g rau 1 kg ntawm tus menyuam qhov hnyav, qhov siab tshaj plaws yuav tsum tsis pub ntau tshaj 0.015 g ib 1 kg.

Yeeb tshuaj sib cuam tshuam

Nrog rau kev siv ua ke ntawm Ofloxin:

• Cimetidine, methotrexate, furosemide thiab cov tshuaj uas thaiv cov hlab zais pa - nce qib ntawm ofloxacin hauv cov ntshav ntshav,
• Nonsteroidal anti-inflammatory tshuaj, derivatives ntawm methylxanthines thiab nitroimidazole - ua rau muaj kev pheej hmoo ntawm cov teebmeem neurotoxic,
• Glucocorticosteroids - ua rau muaj kev pheej hmoo ntawm caj dab, tshwj xeeb tshaj yog rau cov neeg laus,
• Cov tshuaj tiv thaiv ntawm carbonic anhydrase, sodium bicarbonate, citrates (tshuaj uas ua rau cov roj ntsha ua pa) - ua rau muaj kev pheej hmoo ntawm kev tsim cov teebmeem nephrotoxic, crystalluria.

Thaum muab sib xyaw nrog ofloxacin, theophylline tshem tawm kom tsawg li 25%, thiab qib glibenclamide hauv cov ntshav plasma nce ntxiv.

Xav tau kev saib xyuas ntawm cov ntshav coagulation system thaum lub sijhawm sib txuas nrog kev kho mob nrog kev tiv thaiv tsis tau - kev thaiv ntawm cov tshuaj vitamin K.

Cov khoom lag luam thiab cov tshuaj tua kab mob uas muaj cov tshuaj calcium, aluminium, hlau ntsev lossis hlau ntsev txo qhov nqus ntawm ofloxacin, yog li ntawd lub sijhawm nruab nrab ntawm lawv txoj kev tswj hwm thiab kev tswj hwm ntawm Ofloxin yuav tsum yog 2 lossis ntau teev.

Txoj kev pheej hmoo ntawm ncua ntev QT ncua yog nce nrog kev sib xyaw ntawm Ofloxin nrog cov tshuaj tiv thaiv kev puas tsuaj ntawm chav kawm IA thiab III, macrolides, tricyclic antidepressants (tshuaj uas txuas ntxiv QT luv).

Ofloxin tov yog tshuaj sib xyaw nrog 0.9% sodium chloride tov, 5% kev daws teeb meem fructose, Ringer cov kua, 5% piam thaj (dextrose) tov, tab sis nws tsis tuaj yeem tov nrog heparin.

Ofloxin's analogues yog: Zanocin, Zoflox, Ofloxacin, Ofloxacin Protekh, Oflotsid, Lofloks, Vero Ofloxacin, Glaufos, Dancil, Tarivid, Uniflox, Phloxal.

Ofloxine Kev txheeb xyuas

Raws li kev txheeb xyuas feem ntau, Ofloxin yog cov tshuaj tua kab mob muaj txiaj ntsig zoo rau kev kis kab mob kis tau los ntawm cov kab mob me me nkag siab nws.

Hauv qee qhov kev qhia txog kev coj tsis zoo, cov kev mob tshwm sim tau piav qhia, suav nrog kev poob qis, qab plab, mob plab, tsaug zog, qaug zog, tsaus ntuj, thiab ua kom muaj tus mob candidiasis.

Tus nqi ntawm Ofloxin hauv cov chaw muag tshuaj

Kwv yees tus nqi ntawm Ofloxin: kev daws rau Txoj kev lis ntshav 2 mg / ml - 127-163 rubles. rau 1 lub fwj ntawm 100 ml zaj duab xis-txheej ntsiav tshuaj 200 mg - 172–180 rubles. ib pob ntawm 10 pcs.

Kev Kawm Ntawv: Thawj Moscow State Medical University muaj npe tom qab I.M. Sechenov, tshwj xeeb "Tshuaj General".

Cov ntaub ntawv hais txog cov tshuaj raug muab dav dav, muab rau kev qhia tawm thiab tsis hloov chaw cov lus qhia. Kev siv tshuaj rau tus kheej yog qhov txaus ntshai rau kev noj qab haus huv!

Hauv tebchaws Askiv muaj txoj cai lij choj raws li uas tus kws phais neeg tuaj yeem tsis kam ua haujlwm rau tus neeg mob yog tias nws haus luam yeeb lossis rog dhau. Ib tug neeg yuav tsum tso tawm tus cwj pwm tsis zoo, thiab tom qab ntawd, tej zaum, nws yuav tsis xav tau kev phais mob.

Ntau cov tshuaj tau xub pib ua lag luam li tshuaj. Piv txwv li yeeb dawb, tau pib ua lag luam ua tshuaj hnoos. Thiab cocaine tau pom zoo los ntawm cov kws kho mob ua tshuaj loog thiab yog lub zog ntawm kev ua kom lub siab ntev.

Tus neeg noj tshuaj tiv thaiv kab mob feem ntau yuav rov qab muaj kev nyuaj siab. Yog tias ib tug neeg mob nrog kev nyuaj siab ntawm nws tus kheej, nws muaj txhua lub sijhawm tsis nco qab txog lub xeev no tas mus li.

Kev ua haujlwm uas ib tus neeg tsis nyiam yuav muaj kev phom sij rau nws lub siab ntau dua li qhov uas tsis muaj haujlwm hlo li.

Qhov ua kom pom kev vibrator ua ntej nyob rau xyoo 19th. Nws ua haujlwm ntawm lub tshuab tso hluav taws xob thiab nws tau npaj kho qhov mob poj niam.

Muaj ntau cov kev kho mob nthuav tawm heev, xws li kev siv khoom tsis nco qab ntawm cov khoom.Hauv plab ntawm ib tus neeg mob uas tau mob los ntawm tus txiv neej no, 2500 cov khoom txawv teb chaws tau pom.

Yog tias koj poob los ntawm tus nees luav, koj nyiam yob koj lub caj dab ntau dua li yog koj ntog los ntawm nees. Tsuas tsis sim rau refute nqe lus no.

Cov tib neeg uas tau noj tshais ua ntu zus feem ntau yog cov muaj rog.

Raws li kev tshawb fawb, cov poj niam uas haus ob peb khob npias lossis cawv txiv hmab ib lim tiam muaj feem ntau yuav muaj mob khees xaws mis.

Txhua tus neeg muaj tsis tsuas yog nyias tus ntiv tes, tab sis kuj hais lus.

Nrog kev mus saib xyuas lub txaj tanning, txoj kev pheej hmoo ntawm kev mob qog tawv nqaij yuav nce 60%.

Qhov nruab nrab lub neej ntawm cov laug yog tsawg dua ntawm txoj cai.

Cov kws tshawb fawb Asmeskas tau sim cov nas thiab tau xaus lus tias cov kua txiv mab txiv ntoo txwv tsis pub muaj kev txhim kho ntawm cov hlab ntshav ntawm cov ntshav. Ib pawg nas haus dej dawb, thiab lub thib ob ua kua txiv. Raws li qhov tshwm sim, cov hlab ntsha ntawm cov pab pawg thib ob yog pub dawb cov plahaum roj.

Ntau tshaj $ 500 lab tau ib xyoo yog siv rau cov tshuaj tiv thaiv ua xua nkaus xwb nyob hauv Tebchaws Meskas. Koj puas tseem ntseeg tias txoj hauv kev uas thaum kawg kov yeej kev ua xua yuav pom?

Thaum cov neeg nyiam hnia, lawv ib leeg poob 6.4 kcal ib feeb, tab sis tib lub sijhawm lawv sib pauv yuav luag 300 ntau hom kab sib txawv.

Tus naj npawb ntawm cov neeg ua haujlwm hauv chaw ua haujlwm tau nce siab hauv lub cev. Cov qauv no yog tshwj xeeb tshaj yog cov yam ntxwv ntawm cov nroog loj. Kev ua haujlwm hauv chaw ua haujlwm nyiam cov txiv neej thiab poj niam.

Kev Sib Sau thiab daim ntawv ntawm kev tso tawm

Ntawm kev lag luam pharmacological, cov tshuaj tau nthuav tawm ua ob daim ntawv: ntsiav tshuaj rau kev tswj hwm qhov ncauj thiab ib qho kev daws rau infusion. Hloov biconvex ntsiav tshuaj ntawm cov xim dawb los yog daj ntseg daj, ntim hauv lub hlwv ntim ntawm 7 pcs., Hauv daim ntawv cardboard ntawm 2 lub hlwv nrog cov lus qhia rau kev siv. Kev daws yog ntshiab kua daj-ntsuab kua nrog lub yam ntxwv ntawm tus kws tshuaj tsw, muab tso rau hauv lub khob fwj. Cov lus sib xyaw ua ke ntawm ntau yam ntaub ntawv ntawm kev tso tawm tshuaj:

Daim ntawv tso tawm khoom tawm

Coated ntsiav tshuaj

ofloxacin 200 lossis 400 mg (hauv 1 lub tshuaj)

• povidone
• lactose monohydrate,
• crospovidone
• magnesium stearate,
• talcum hmoov
• pob kws nplej siab
• poloxamer.

Txoj kev lis ntshav daws

ofloxacin 200 mg (hauv 1 lub raj mis)

• disodium dihydrate,
• dej rau kev txhaj tshuaj.

Kev siv ofloxine

Ofloxin yog muaj nyob ntawm qhov muaj ntau yam mob kis thiab mob. Cov lus qhia rau kev siv cov tshuaj tua kab mob no yog:

• mob ntsws
• mob ntsws
• mob rau daim npluag qhwv
• rwj
• blepharitis
• vaginitis
• vasculitis
• dermatitis
• laryngitis
• pom mob pob txha
• colpitis
• jade
• enterocolitis
• prostatitis
• salpingitis
• gonorrhea
• dacryocystitis
• pyelonephritis.

Kev siv ofloxine siv li cas

Ofloxin ntsiav tshuaj yuav tsum noj qhov ncauj thaum noj mov lossis tom qab noj mov. Cov koob tshuaj thiab lub sijhawm siv tshuaj kho yog raug xaj los ntawm kws kho mob tom qab kuaj thiab tau txais cov txiaj ntsig sim. Tus qauv pom zoo siv tshuaj tua kab mob:

• Hauv cov mob sib kis thiab mob sib kis tau yooj yim, kev siv Ofloxin yog qhia rau 0.4 g ib zaug thaum sawv ntxov. Lub sijhawm kho yog tsis ntau tshaj 10 hnub.
• Hauv cov ntawv hnyav lossis hnyav dua, qhov tsuas tshuaj tau nce rau 0.8 g.
• Txog kev kho mob ntawm cov kab mob tsis yooj yim ntawm cov mob ntawm lub qhov zis nqaum, 0.2 g yuav tsum tau noj nyob rau 3-5 hnub.

Cov tshuaj nyob rau hauv daim ntawv ntawm tov rau Txoj kev lis ntshav yog muab tshuaj rau hauv intravenously. Kev kho mob pib nrog kev txhaj tshuaj ib zaug qeeb ntawm 0.2 g ntawm cov tshuaj rau 40-60 feeb. Tom qab kev txhim kho, tus neeg mob pauv mus rau kev txais tos ntawm cov ntsiav tshuaj hauv tib lub tshuaj. Rau cov neeg mob uas muaj mob raum lossis lub siab tsis ua haujlwm, mob ntsws, txhua hnub cov tshuaj yuav tsum tsis pub ntau dua 0.4 g.

Noj ntau dhau

Qhov tseem ceeb tshaj plaws ntawm kev siv ib zaug lossis niaj hnub ntawm Ofloxin tuaj yeem ua rau cov tsos mob hauv qab no ntawm kev siv ntau tshaj:

• kiv taub hau
• ntuav
• lus txhais
• tsis nco qab
• cev qhuav dej
• qog ntshav,
• bronchospasm
• tsis meej pem,
• tsaug zog

Yog tias Ofloxin raug coj mus rau hauv cov ntsiav tshuaj, kev mob plab yuav tsum tau ua. Txoj kev kho ntxiv yog nyob ntawm qhov chaw kuaj mob.

Cov nqe lus ntawm kev muag khoom thiab kev cia khoom

Ofloxin kev daws teeb meem thiab cov ntsiav tshuaj yog faib los ntawm cov khw muag tshuaj los ntawm cov tshuaj. Cov tshuaj yuav tsum muab cia rau qhov kub ntawm +10 ° C txog +25 ° C hauv qhov chaw tsis zoo rau cov menyuam yaus me. Lub txee lub neej ntawm cov ntsiav tshuaj yog 3 xyoos, kev daws teeb meem tau muab ntim - 1 xyoos, hauv pob qhib - 30 hnub. Nws yog txwv tsis pub siv cov tshuaj tom qab hnub tas sij hawm.

Tso Tawm Cov Ntawv

• Cov ntsiav tshuaj: puag ncig hauv cov duab, coated nrog ib qho ntxoov ntxoo dawb, kev siv tshuaj ntawm 200 mg thiab 400 mg.
• 0.2% kev daws teeb meem rau kev tswj hwm: kev daws teeb meem ntshiab, tej zaum yuav muaj xim daj, muaj nyob hauv 100 ml vials.
• Tshuaj pleev - dawb, tej zaum yuav nrog zas daj, yog muaj nyob rau hauv txhuas leeg ntawm 15 mg thiab 30 mg.

Ofloxacin Kev Kho Mob

Ofloxacin Cov Tshuaj Txhaj
Qhov ntau npaum li cas ntawm cov tshuaj tua kab mob no rau ntau yam kabmob txawv, thiab nws yuav tsum yog kws kho mob sau tseg.

Yog li, rau kev kho mob ntawm cov mob genitourinary, 1 ntsiav tshuaj (200 mg) feem ntau yog hais qhia 1-2 zaug ib hnub rau 7-10 hnub.

Hauv kev mob gonococcal mob siab, ib koob tshuaj 4 txog 6 ntsiav tshuaj (200 mg) yog qhia.

Rau kev kho mob ntawm prostatitis, 1.5 mus rau 2 ntsiav tshuaj (200 mg) tau sau tseg 2 zaug hauv ib hnub.

Txog rau mob ncauj plab, noj 1 ntsiav tshuaj (200 mg) 2 zaug hauv ib hnub rau 5 hnub. Raws li kev cog lus, 2 ntsiav tshuaj (200 mg) ib hnub ib zaug.

Raws li kev txhim kho ntawm sepsis, noj 2 ntsiav tshuaj (200 mg) 3 zaug hauv ib hnub.

Rau cov kab mob hauv lub raum, kev kho mob yog kho raws tus kheej, nrog thawj koob yog 1 ntsiav tshuaj (200 mg), tom qab ntawd 1 ntsiav tshuaj ib hnub lossis 1 ntsiav tshuaj hauv 2 hnub.

Nrog kev ua txhaum loj ntawm daim siab, tsis txhob haus ntau tshaj 2 ntsiav tshuaj (200 mg) ib hnub.

Nyob rau hauv kev kis mob hnyav ntawm cov genitourinary plab hnyuv siab raum thiab kab mob hauv lub raum, ib qho kev daws teeb meem ntawm cov tshuaj yog kws kho nyob rau hauv daim ntawv ntawm dauv, 100 ml ntawm cov tshuaj 1-2 zaug ib hnub.

Nrog rau tus kab mob gonococcal, cov tshuaj tau muab tshuaj rau hauv ib koob tshuaj 200 mg 2 zaug hauv ib hnub.

Ofloxacin rau mob chlamydia

Rau kev kho mob chlamydia, ib chav kawm ntawm kev kho mob nrog cov tshuaj nyob rau hauv daim ntawv ntawm kev txhaj tshuaj lossis ntsiav tshuaj yog tshuaj, thaum cov nyhuv ntawm kev kho mob tsis txawv.

Cov koob tshuaj yog sau tseg ib tus zuj zus, feem ntau 1 ntsiav tshuaj (txhaj tshuaj) 1-2 zaug ib hnub.

Thaum kho, nws tsis pom zoo kom siv cov tshuaj uas txo cov kua qaub ntawm lub plab.
Ntau Txog Chlamydia

Ofloxacin nrog ureaplasmosis

Cov tshuaj yog rau cov tshuaj tua kab mob sab-spectrum, yog li ntawd, nws tau sau tseg rau kev kho mob ntawm ureaplasmosis. Tib lub sijhawm, Ofloxacin suav hais tias yog cov tshuaj zoo tshaj plaws los kho tus mob no.

Siv cov tshuaj hauv daim ntawv ntawm cov ntsiav tshuaj ntawm 400 mg 2 zaug ib hnub rau 7-10 hnub.
Ntau txog ureaplasmosis

Kev cuam tshuam ntawm ofloxacin nrog lwm yam tshuaj

• Ua rau cov tshuaj noj npaj muaj antacids, sulfates, calcium, hlau, zinc yuav tsum yog ob teev tom qab noj Ofloxacin rau kev nqus zoo dua.
• Nws tsis pom zoo rau kev noj tshuaj nrog tshuaj tiv thaiv kev tiv thaiv kom tsis txhob ntxiv kev txhawb nqa ntawm lub hauv nruab nrab ntawm cov hlab ntsha txhawm.
• Ntawm cov ntshav qab zib mellitus, nws yog qhov tsim nyog los tswj cov theem ntawm cov piam thaj.

Kev tshuaj xyuas txog cov tshuaj

Raisa, 68 xyoo
"Ofloxacin tau sau tseg rau hauv tsev kho mob tom qab kev ua haujlwm. Kuv tau mob o, muaj mob hnyav heev. Tom qab 2 hnub uas tau noj cov tsos mob, cov tsos mob ploj thiab pib sai sai."

Nikolay, 28 xyoo
"Lawv kuaj tus mob ureaplasmosis, Kuv xav tias nws tsis tuaj yeem siv tau. Kuv tau coj ofloxacin, muaj kev noj qab nyob zoo hauv ib lub lis piam."

Natalia, hnub nyoog 52 xyoo
"Kuv khaws cov pob qij txha, sim ib pawg tshuaj pleev, tsis muaj kev cuam tshuam, thaum kawg kuv yuav tsum mus ntsib kws kho mob. Ofloxacin qhia, nws raug kho rau ob peb hnub, txhua yam raug tshem tawm."

Yuav luag txhua tus neeg mob hauv kev txheeb xyuas pom tias tus nqi qis ntawm cov tshuaj hauv kev sib xyaw nrog txoj kev kho kom zoo.

Tsuas tshuaj thiab tswj hwm

Kev noj tshuaj ntau npaum li cas yog nyob ntawm hom thiab qhov mob kis tau, nrog rau kev nkag siab ntawm cov kab mob me me mus rau qhov kev txiav txim ntawm cov tshuaj, cov xwm txheej dav dav ntawm tus neeg mob, lub xeev ua haujlwm ntawm lub raum thiab mob siab.

Ntsiav tshuaj
Ofloxin noj ntawm qhov ncauj, ntxuav nrog dej, ua ntej lossis thaum noj mov. Cov ntsiav tshuaj yuav tsum noj tag nrho. Txuag siv nrog antacids yuav tsum zam.

Qhov pom zoo txhua hnub koob tshuaj Ofloxin yog 200-600 mg, cov neeg mob hnyav lossis cov neeg mob nyhav dhau los nws yuav nce ntxiv mus rau 800 mg (koob ntawm 400 mg tuaj yeem noj ib hnub ib zaug, zoo dua thaum sawv ntxov, ntau dua qhov koob tshuaj tuaj yeem faib 2 txais tos).

Lub sijhawm siv ntawm kev kawm yog 7-10 hnub.

Nrog rau kev kis tsis yooj yim ntawm cov mob txeeb zig qis dua, Ofloxin raug kho rau 3-5 hnub nyob rau ib hnub 200 mg, nrog mob gonorrhea - ib zaug 400 mg.

Tom qab tus neeg mob lub mob zoo dua, kev kho mob siab pib los ntawm ofloxacin tuaj yeem txuas nrog Ofloxin sab hauv tsis tas hloov cov tshuaj.

Txoj kev lis ntshav daws
Ofloxin yog tshuaj kom paub txog pob qij txha.

Qhov tshuaj thawj zaug yog 200 mg ib zaug, tus nqi tswj hwm yog nyob rau hauv 30-60 feeb. Tom qab tus neeg mob hloov kho, Ofloxin yuav tsum pauv mus hauv sab hauv yam tsis tas pauv cov koob tshuaj.

Cov tshuaj pom zoo kom noj tshuaj (nyob ntawm thaj chaw muaj tus mob):

• Cov hlab zis: 1-2 zaug hauv ib hnub, 100 mg txhua,
• Cov mob hauv ENT, ua pa ntawm daim tawv nqaij, tawv nqaij, pob txha, cov nqaij mos, mob plab, pob qij txha, nrog rau cov leeg mob: 2 zaug hauv ib hnub, 200 mg txhua qhov (nce 2 zaug hauv ib zaug xwb),,
• Mob raum thiab chaw mos: 2 zaug ib hnub, 100-200 mg.

Cov neeg mob uas muaj lub cim txo qis hauv kev tiv thaiv kev tiv thaiv kom tsis txhob muaj kab mob, Ofloxin yog muab rau cov leeg (200 mg ntawm Ofloxin hauv 5% kua nplaum). Lub sijhawm tiv thaiv ntawm Txoj kev lis ntshav yog 30 feeb. Koj tuaj yeem siv cov kev qhia ntawv uas nyuam qhuav kho tshiab.

Tag nrho cov ntaub ntawv cov tshuaj ofloxine
Nrog kev ua haujlwm tsis zoo rau lub raum, cov koob tshuaj yuav tsum tau kho (nyob ntawm creatinine tshem tawm):

• Los ntawm 50 txog 20 ml ib feeb: 2 zaug hauv ib hnub, 50% ntawm ib zaug tshuaj lossis 1 zaug ib hnub, 100% ntawm ib zaug,
• Tsawg dua 20 ml ib feeb: qhov tshuaj thawj zaug yog 200 mg, thiab tom qab ntawd ces txhua lwm hnub, 100 mg rau ib hnub.

Nrog peritoneal lim ntshav thiab tshuaj lom neeg mob, Ofloxin yog tshuaj txhua 24 teev ntawm 100 mg.

Cov neeg mob siab tsis ua haujlwm siab yuav tsum tsis pub tshaj qhov siab tshaj plaws txhua hnub ntawm 400 mg.