Protaphane® HM (Protaphane® HM)

Tus neeg sawv cev hypoglycemic, nruab nrab insulin.
Npaj: PROTAFAN® NM
Cov tshuaj nquag ntawm cov tshuaj: isophane insulin tib neeg raug tshem tawm
ATX Encoding: A10AC01
KFG: Nruab Nrab Sij Hawm Rau Tib Neeg Qhov Insulin
Reg. tooj: P No. 014722/01
Hnub sau npe: 04/20/07
Tswv reg reg. acc .: NOVO NORDISK A / S

Daim ntawv tso tawm Protafan nm, ntim tshuaj thiab muaj pes tsawg leeg.

Kev ncua rau sc tswj hwm ntawm cov xim dawb, thaum stratified, tsim cov dej nag dawb thiab xim tsis muaj xim lossis yuav luag tsis muaj xim zoo nkauj, nrog kev nplawm, qhov nag lossis daus yuav tsum rov ua dua.

1 ml
isofan insulin (tib neeg kev tsim kho tshuab)
100 IU *

* 1 IU sib raug rau 35 μg ntawm cov tshuaj insulin tsis txaus rau tib neeg.

10 ml - lub khob ntawm cov iav tsis muaj xim (1) - pob ntawv los ntawm cov duab los qhia.

LUS PUB HUAM TXHEEJ TXHEEM MOO ZOO.
Txhua cov lus qhia tau muab nthuav tawm tsuas yog ua rau kom paub txog cov tshuaj, koj yuav tsum sab laj nrog tus kws kho mob txog kev siv.

Pharmacological kev ua ntawm Protafan nm

Tus neeg sawv cev hypoglycemic, nruab nrab insulin tau los ntawm kev tsim hluav taws xob, yog zoo tib yam rau tib neeg cov insulin.

Sib cuam tshuam nrog ib qhov tshwj xeeb receptor rau ntawm sab nraud ntawm lub hlwb, tsim cov txheej txheem insulin. Los ntawm nce cov synthesis ntawm cAMP (hauv cov roj ntsha thiab lub siab hlwb) lossis nkag ncaj qha rau hauv lub cell (leeg), insulin receptor complex stimulates intracellular processes, suav nrog synthesis ntawm cov lej ntawm cov enzymes tseem ceeb (suav nrog rau hexokinase, pyruvate kinase, glycogen synthetase).

Kev txo qis hauv cov concentration ntawm cov piam thaj hauv cov ntshav yog tshwm sim los ntawm kev nce ntxiv hauv nws txoj kev thauj mus los, kev nqus thiab pov tseg ntau los ntawm cov nqaij mos, ua kom muaj zog ntawm lipogenesis, glycogenogenesis, synthesis protein, thiab txo tus nqi ntawm cov piam thaj los ntawm lub siab (txo qis hauv glycogen tawg).

Pharmacokinetics ntawm cov tshuaj.

Kev nqus thiab pib ntawm kev nqis tes yog nyob ntawm txoj kev ntawm kev coj (sc lossis intramuscularly), qhov chaw nyob (plab, ncej puab, pob tw) thiab qhov ntim ntawm kev txhaj tshuaj, qhov concentration ntawm insulin hauv tshuaj. Nws muab faib ua qhov tsis sib luag hauv daim ntaub, tsis nkag mus rau hauv qhov chaw nres thiab nkag mus rau niam mis. Nws yog rhuav tshem los ntawm insulinase, feem ntau yog nyob hauv daim siab thiab lub raum. Nws yog tawm los ntawm lub raum (30-80%).

Dosage thiab txoj hauv kev ntawm kev tswj hwm tshuaj.

Nkag s / c, 1-2 zaug / hnub, 30-45 feeb ua ntej noj tshais. Qhov chaw txhaj tshuaj yuav tsum tau hloov txhua zaus. Hauv qhov xwm txheej tshwj xeeb, a / m cov lus qhia yog ua tau.

Hauv / hauv kev qhia ntawm cov tshuaj insulin ntawm lub sijhawm nruab nrab tsis tso cai.

Cov koob tshuaj tau teeb tsa ib tus zuj zus, nyob ntawm cov ntsiab lus ntawm cov piam thaj hauv cov ntshav thiab zis, cov yam ntxwv ntawm chav kawm ntawm tus kabmob.

Qhov tshwm sim los ntawm Protafan nm:

Cov kev tawm tsam vim qhov cuam tshuam ntawm cov metabolism hauv kev ua kom yuag: hypoglycemia (pallor ntawm daim tawv nqaij, nce tawm hws, palpitations, tshee tshee, tshaib plab, ntxhov siab, teeb meem hauv lub qhov ncauj, mob taub hau). Kev mob ntshav qog ntshav qis tuaj yeem ua rau txhim kho kev mob hypoglycemic coma.

Kev ua xua: tsis tshua muaj - tawm pob ntawm daim tawv nqaij, Quincke's edema, qee qhov - anaphylactic ceeb.

Cov tshuaj tiv thaiv hauv zos: hyperemia, o, khaus, nrog siv ntev - lipodystrophy.

Lwm yam: kab mob edema, qhov hloov pauv sai sai (feem ntau thaum pib kho).

Siv thaum cev xeeb tub thiab lactation.

Thaum cev xeeb tub, nws yog ib qho tsim nyog yuav tsum coj mus rau hauv qhov kev txo qis hauv qhov xav tau ntawm cov tshuaj insulin hauv thawj peb lub hlis lossis nce ntxiv ntawm zaum ob thiab thib peb. Thaum lub sijhawm thiab yug tom qab yug, insulin yuav tsum poob ntau.

Thaum lub sijhawm lactation, kev soj ntsuam txhua hnub yog xav tau rau ntau lub hlis (txog thaum qhov xav tau cov tshuaj insulin yuav ruaj khov)

Cov lus qhia tshwj xeeb rau kev siv Protafan nm.

Nrog kev ceev faj, qhov ntau ntawm cov tshuaj raug xaiv hauv cov neeg mob uas muaj cov kab mob cerebrovascular ua ntej lawm raws li hom ischemic thiab nrog cov ntawv hnyav ntawm ischemic mob plawv.
Qhov xav tau ntawm insulin tuaj yeem hloov pauv ntawm cov xwm txheej hauv qab no: thaum hloov mus rau lwm hom insulin, thaum hloov pauv kev noj zaub mov, raws plab, ntuav, thaum hloov qhov ib txwm ntawm kev ua haujlwm ntawm lub cev, hauv cov kab mob ntawm lub raum, mob siab, pituitary, thyroid caj pas, thaum hloov chaw txhaj tshuaj.
Yuav tsum tau txhaj tshuaj insulin rau cov mob sib kis, cov thyroid tsis ua haujlwm, Addison's disease, hypopituitarism, mob raum tsis ua haujlwm, thiab mob ntshav qab zib mellitus hauv cov neeg mob uas muaj hnub nyoog 65 xyoos.

Qhov hloov ntawm tus neeg mob mus rau tib neeg cov tshuaj insulin yuav tsum yog ib qho kev txiav txim siab ncaj thiab nqa tawm tsuas yog nyob hauv kev saib xyuas ntawm kws kho mob.

Cov laj thawj ntawm kev ua ntshav siab tuaj yeem yog: insulin noj ntau dhau, hloov tshuaj, hla zaub mov, ntuav, raws plab, kev ntxhov siab ntawm lub cev, cov kab mob uas txo qis qhov xav tau ntawm insulin (mob raum thiab mob siab, nrog rau kev ua haujlwm ntawm adrenal cortex, pituitary lossis thyroid caj pas), hloov chaw txhaj tshuaj (piv txwv, tawv nqaij ntawm lub plab, xub pwg, ncej puab), ntxiv rau kev sib cuam tshuam nrog lwm yam tshuaj. Nws muaj peev xwm ua kom txo qis ntawm cov piam thaj hauv cov ntshav thaum hloov mus rau tus neeg mob los ntawm tsiaj insulin mus rau tib neeg cov insulin.

Tus neeg mob yuav tsum tau qhia paub txog cov tsos mob ntawm lub xeev hypoglycemic, txog thawj cov tsos mob ntawm tus mob ntshav qab zib tsis nco qab thiab txog qhov yuav tsum tau qhia rau tus kws kho mob txog txhua yam kev hloov pauv hauv nws tus mob.

Yog hais tias qhov ua rau lub ntsej muag tsis txaus, yog tias tus neeg mob nco qab, nws tau txiav txim siab dextrose sab hauv, s / c, i / m lossis iv txhaj tshuaj glucagon lossis iv hypertonic dextrose tov. Nrog rau kev txhim kho lub ntsej muag tsis nco qab, 20-40 ml (txog 100 ml) ntawm 40% dextrose tov yog txhaj iv rau hauv qhov dej kom txog thaum tus neeg mob tawm ntawm lub cev tsis nco qab.

Cov neeg mob ntshav qab zib tuaj yeem nres cov ntshav qabzib uas tau txais los ntawm lawv los ntawm kev noj cov piam thaj lossis cov zaub mov uas muaj cov khoom noj (carbohydrates) (cov neeg mob tau pom zoo kom muaj tsawg kawg 20 g suab thaj nrog lawv).

Cawv kev haus dej haus cawv rau cov neeg mob tau txais cov tshuaj insulin yuav txo.

Cuam tshuam rau kev muaj peev xwm tsav tsheb thiab tswj cov tshuab

Kev ntsuam xyuas kev txhim kho hypoglycemia tuaj yeem cuam tshuam cov peev xwm ntawm cov neeg mob tsav tsheb thiab ua haujlwm nrog cov qauv.

Kev sib cuam tshuam ntawm Protafan nm nrog lwm yam tshuaj.

Cov nyhuv hypoglycemic yog txhim kho los ntawm sulfonamides (suav nrog cov tshuaj tiv thaiv hypoglycemic qhov ncauj, sulfanilamides), MAO inhibitors (suav nrog furazolidone, procarbazine, selegiline), carbonic anhydrase inhibitors, ACE inhibitors, NSAIDs (suav nrog salicylides), anabolic (suav nrog stanozolol, oxandrolone, methandrostenolone), androgens, bromocriptine, tetracyclines, clofibrate, ketoconazole, mebendazole, theophylline, cyclophosphamide, fenfluramine, lithium npaj, pyridoxine, quinidine, quinine, chloroquin.

Glucagon, somatropin, GCS, tshuaj tiv thaiv muaj qhov ncauj, estrogens, thiazide thiab "voj" diuretics, calcium channel blockers, cov thyroid hormones, heparin, sulfin pyrazone, sympathomimetics, danazole, tricyclic antidepressants, calcium chloride, moron, txo cov nyhuv hypoglycemic. nicotine, phenytoin, epinephrine, histamine H1 receptor blockers.

Beta-blockers, reserpine, octreotide, pentamidine tuaj yeem ob leeg txhim kho thiab txo cov nyhuv hypoglycemic ntawm insulin.

Cov tshuaj tsis sib haum nrog kev daws thiab lwm yam tshuaj.

Nosological kev faib tawm (ICD-10)

Protafan ® HM Penfill ®

Cov Chaw Tshuaj Kho Mob

Cov nyhuv tsim tawm 1.5 teev tom qab kev tswj hwm sc, nce mus txog qhov siab tshaj plaws tom qab 4-12 teev thiab kav ntev li 24 teev. Protafan NM Penfill rau cov tshuaj tiv thaiv kabmob ntshav qab zib mulinitus yog siv los ua cov kab mob basal insulin nyob rau hauv kev sib xyaw nrog luv-insulin, rau qhov tsis-insulin-dependant - raws li kev kho mob monotherapy , thiab kev sib xyaw ua ke nrog cov kab hluav taws xob ua haujlwm sai.

Tsuas tshuaj thiab tswj hwm

Protafan ® HM Penfill ®

P / c. Cov tshuaj yog npaj rau subcutaneous thawj coj. Kev ncua ntawm insulin tsis tuaj yeem nkag mus rau hauv / hauv.

Cov koob tshuaj ntawm cov tshuaj tau xaiv ib tus zuj zus, ua raws li qhov xav tau ntawm tus neeg mob. Feem ntau, cov tshuaj insulin yog nyob nruab nrab ntawm 0.3 thiab 1 IU / kg / hnub. Cov kev xav tau txhua hnub rau insulin tuaj yeem siab dua nyob rau hauv cov neeg mob uas muaj insulin tsis kam (piv txwv li, thaum pub, nrog rau cov neeg mob rog rog), thiab qis dua hauv cov neeg mob uas muaj cov insulin endogenous ntau lawm.

Protafan ® NM tuaj yeem siv tau ob qho tib si hauv monotherapy thiab muaj kev sib xyaw nrog sai los luv luv ua yeeb yam insulin.

Protafan ® NM feem ntau yog ua rau subcutaneously hauv tus ncej puab. Yog tias qhov no yooj yim, tom qab ntawd hno tuaj yeem ua rau hauv pem hauv ntej lub plab phab ntsa, hauv thaj chaw gluteal lossis hauv thaj av ntawm deltoid leeg ntawm lub xub pwg. Nrog kev qhia txog cov tshuaj rau hauv tus ncej puab, muaj qhov nqus qis dua li thaum qhia mus rau lwm thaj chaw. Yog tias kev txhaj tshuaj tau ua rau hauv daim tawv nqaij txuas ntxiv, qhov kev pheej hmoo ntawm kev tsis txaus ntshai ntawm cov thawj coj ntawm cov tshuaj no raug txo kom tsawg.

Lub koob yuav tsum nyob twj ywm hauv qab ntawm daim tawv nqaij tsawg kawg 6 vib nas this, uas tuaj yeem lav ua kom puv koob. Nws yog ib qho tsim nyog los hloov qhov chaw txhaj tshuaj tsis pub dhau thaj chaw anatomical kom tiv thaiv kev txhim kho ntawm lipodystrophy.

Protafan ® NM Penfill ® tsim los siv nrog Novo Nordisk insulin txhaj tshuaj thiab NovoFine ® lossis NovoTvist. Koob. Cov lus qhia ntxaws ntxaws rau kev siv thiab kev tswj hwm ntawm cov tshuaj yuav tsum tau ua kev cai.

Cov kab mob tsis haum, tshwj xeeb tshaj yog kis thiab nrog kub taub hau, feem ntau ua rau lub cev xav tau cov tshuaj insulin. Koob tshuaj kuj tseem yuav tsum tau ua yog tias tus neeg mob tau muaj cov kab mob ntawm lub raum, mob siab, ua haujlwm tsis zoo hauv lub qog, lub caj pas pituitary lossis lub qog ua haujlwm. Qhov xav tau kom haum rau kev txhaj tshuaj kuj tuaj yeem tshwm sim thaum hloov lub cev lossis cov neeg mob ib txwm noj. Koob tshuaj yuav tau tuaj yeem hloov kho thaum hloov tus neeg mob los ntawm ib hom tshuaj insulin mus rau lwm tus

Noj ntau dhau

Cov tsos mob kev txhim kho hypoglycemia (tawm hws txias, tawm hws, tshee tshee, tshaib plab, ntxhov siab, chim siab, pallor, mob taub hau, tsaug zog, tsis muaj zog, hais lus thiab pom kev tsis pom kev zoo, kev nyuaj siab). Kev mob ntshav khov ntau heev tuaj yeem ua rau lub hlwb ua haujlwm ib ntus lossis tas mus li, tsis nco qab, thiab tuag.

Kev Kho Mob: qab zib lossis kua qab zib tov sab hauv (yog tias tus neeg mob nco qab zoo), s / c, i / m lossis iv - glucagon lossis iv - qabzib.

Cov nqi hauv cov khw muag tshuaj hauv Moscow

Cov ntaub ntawv muab ntawm cov nqi tshuaj tsis yog qhov muag rau muag lossis yuav khoom.
Cov ntaub ntawv yog npaj tsuas yog los sib piv cov nqi hauv cov chaw muag tshuaj hauv kev ua haujlwm raws li Nqe Lus 55 ntawm Tsoomfwv Txoj Cai "ntawm Kev Tswj Xyuas Tshuaj" hnub tim 12.04.2010 N 61-ФЗ.

Tso tawm daim ntawv thiab muaj pes tsawg leeg

Dosage form - raug tshem tawm rau kev tswj hwm subcutaneous: dawb, thaum sawv exfoliates rau hauv cov kua tsis muaj xim thiab cov dej nag sai sai, nws nthuav tawm nrog nplawm (10 ml hauv lub khob tsis muaj xim, 1 lub khob hauv pob ntawv los).

Cov khoom siv nquag: insulin-isophan (tib neeg kev tshawb fawb txog tshuaj lom neeg), hauv 1 lub raj mis - 100 Thoob ntiaj teb, uas tau sib haum rau 3.5 mg ntawm insulin tib neeg lub cev tsis txaus.

Cov khoom siv ntxiv: cov tshuaj protamine sulfate, phenol, metacresol, sodium hydrogen phosphate dihydrate, glycerol, zinc chloride, sodium hydroxide thiab / lossis hydrochloric acid, dej rau kev txhaj tshuaj.

Tsuas tshuaj thiab tswj hwm

Protafan NM muab tshuaj subcutaneously.

Cov koob tshuaj tau xaiv ib qho zuj zus raws li cov kev xav tau ntawm tus neeg mob, feem ntau nws yog 0.3-1 IU / kg ib hnub. Qhov kev xav yuav qis dua nyob rau hauv cov neeg mob uas muaj cov tshuaj endulinous insulin ntau dua lossis ntau dua hauv cov neeg mob insulin tsis kam (piv txwv, rog dhau thiab pub pub).

Protafan NM tuaj yeem siv tau los ua ib qho yeeb tshuaj thiab hauv kev sib xyaw nrog kev siv tshuaj insulin sai lossis luv.

Nyob rau hauv rooj plaub thaum muaj qhov xav tau kev siv tshuaj insulin ntau ntxiv, qhov kev ncua yuav siv tau li insulin basal (kev txhaj tshuaj thaum yav tsaus ntuj thiab / lossis thaum sawv ntxov) ua ke nrog luv luv lossis ceev ua yeeb yam insulin (nws txoj kev txhaj tshuaj yuav tsum txuas nrog zaub mov). Yog tias nws muaj peev xwm ua tiav kev tswj hwm kev noj qab haus huv ntawm glycemia, ces cov teeb meem ntshav qab zib feem ntau tshwm sim tom qab, hauv kev sib txuas nrog ib tus twg yuav tsum siv zog ua kom zoo tshaj ntawm cov tswj kev zom zaub mov, ua tib zoo tswj cov qib ntawm cov piam thaj hauv cov ntshav.

Protafan HM feem ntau yog tswj xyuas subcutaneously hauv thaj chaw hauv ncej puab. Koj tuaj yeem txhaj tshuaj mus rau sab xub ntiag lub plab phab ntsa, mus rau hauv thaj chaw deltoid ntawm lub xub pwg, lossis mus rau thaj chaw gluteal. Txawm li cas los xij, hauv thawj kis, kev nqus sai dua ntawm cov tshuaj tau sau tseg.

Txo txoj kev pheej hmoo ntawm qhov kev txhaj tshuaj intramuscular tshaj plaws, kev txhaj tshuaj yuav tsum tau ua rau lub cev nqaij txuas ntxiv. Txhawm rau tiv thaiv kev txhim kho ntawm lipodystrophy, nws pom zoo kom hloov chaw txhaj tshuaj hauv thaj av anatomical.

Hauv cov neeg mob uas tsis zoo lub raum thiab hepatic muaj nuj nqi, qhov xav tau ntawm insulin yog txo, yog li ntawd, kev kho tshuaj Protafan NM yog yuav tsum tau kho.

Qhov kev ncua tsuas yog muab nrog cov tshuaj insulin nrog cov nplai uas tso cai rau koj los ntsuas qhov kev ntsuas uas xav tau hauv cov kev ua. Vials tsuas yog siv rau tus kheej nkaus xwb.

Ua ntej siv Protafan NM, nws yog qhov tsim nyog:

• Kuaj cov ntawv ntim thiab xyuas kom meej tias hom tshuaj insulin raug xaiv,
• Cia cov tshuaj kom sov rau chav sov thiab tsuas yog tom qab sib xyaw kev txwv,
• Txhawm rau rho tawm roj hmab nres.

Cov tshuaj txwv tsis pub siv rau qee yam hauv qab no:

• Hauv cov tshuaj insulin
• Lub hau npog lub raj mis ploj lawm los yog xoob
• Cov tshuaj tau muab khaws cia tsis raug los yog khov,
• Tom qab sib tov, cov tshuaj tsis rov mob dua qub (tsis dhau los ua huab thiab dawb).

Cov txheej txheem kev txhaj tshuaj thaum siv tsuas yog Protafan NM:

• Caw qhov muab ncua, kom ua li no, yob lub raj mis nruab nrab ntawm xib teg (preheating nws mus rau chav sov),
• Kos cua rau hauv lub taub hau hauv ib qho npaum li cas raws li qhov yuav tsum tau txhaj ntawm insulin,
• Qhia cov pa mus rau hauv lub vial los ntawm kev tho lub taub roj hmab nres thiab nias lub taub dej nqus cov nqus dej,
• Tig lub raj mis sab hauv qis dua, tau txais qhov tsim nyog koob tshuaj insulin,
• Tshem tawm cov koob txhaj tshuaj ntawm lub khob thiab tshem tawm cov cua los ntawm rab koob txhaj tshuaj,
• Kuaj qhov tseeb
• Hno tam sim.

Cov txheej txheem kev txhaj tshuaj thaum siv Protafan NM txuam nrog luv luv ua yeeb yam insulin:

• Do cov kev ncua (raws li tau piav los saum no),
• Nqa cov pa mus rau hauv cov koob txhaj tshuaj hauv lub ntim sib haum rau qhov tshuaj ntawm Protafan NM, ntxig rau nws rau hauv lub raj mis kom tsim nyog thiab tshem tawm cov koob,
• Txhawm rau kom nqus huab cua mus rau hauv cov phwj hauv qhov ntim uas sib xyaw nrog cov koob tshuaj luv luv ntawm kev tiv thaiv insulin (ICD), nkag rau hauv lub raj mis uas tsim nyog,
• Tig lub raj mis sab xub ntiag thiab ntaus lub koob tshuaj ntawm ICD,
• Noj tawm rab koob, tshem tawm cov cua ntawm lub koob txhaj thiab tshuaj xyuas qhov tseeb ntawm cov koob tshuaj sau,
• Ntxig lub koob rau hauv lub raj mis nrog Protafan NM, tig lub raj mis sab hauv thiab ntaus lub koob txhaj tshuaj,
• Tshem tawm cov koob txhaj tshuaj ntawm lub khob thiab cua los ntawm cov koob txhaj tshuaj, xyuas qhov tseeb ntawm cov koob tshuaj sau,
• Tam sim ntawd txhaj cov tshuaj pleev ntev thiab ua yeeb yam luv luv.

Yuav tsum sau cov tshuaj Insulin hauv cov kab uas hais los saud!

Cov kev cai ntawm kev tswj hwm tshuaj:

• Nrog ob tug ntiv tes, muab daim tawv nqaij ua ib daim, ntxig ib rab koob rau hauv nws lub hauv paus ntawm kaum ntawm 45 ° thiab txhaj tshuaj insulin hauv qab daim tawv nqaij,
• Tseg tawm rab koob tso rau hauv qab ntawm daim tawv nqaij tsawg kawg 6 vib nas this kom ntseeg tau tias qhov koob tau siv tau.

Sab sij huam

Cov kev mob tshwm sim thaum kho nrog Protafan NM feem ntau yog koob tshuaj thiab yog vim qhov pharmacological ua ntawm insulin. Feem ntau cov kev phiv tshuaj yog hypoglycemia, uas ib txwm muaj kev txhim kho thaum muaj qhov hnyav tseem ceeb ntawm cov koob tshuaj insulin hauv kev cuam tshuam nrog qhov xav tau. Kev mob ntshav nce siab ntau tuaj yeem nrog kev ploj thiab tsis nco qab, thiab ua rau lub hlwb ua haujlwm tsis zoo thiab ua rau tuag taus.

Cov tshuaj phiv:

Los ntawm ib sab hauv lub cev tiv thaiv kab mob: ncaug ((1/1000, 5 11111 Ntsuas: 5 - 1 pov npav

Cev xeeb tub thiab lactation

Tsis muaj kev txwv txog kev siv cov tshuaj insulin thaum cev xeeb tub, vim tias cov tshuaj insulin tsis hla qhov chaw tiv thaiv.

Ob lub qog ntshav qab zib thiab hyperglycemia, uas tuaj yeem tsim kho thaum muaj kev xaiv tsis zoo, ua rau muaj kev pheej hmoo ntawm cov mis tsis ua haujlwm thiab kev tuag ntawm tus menyuam hauv plab. Cov poj niam cev xeeb tub uas muaj ntshav qab zib yuav tsum tau saib xyuas thoob plaws lub sijhawm lawv cev xeeb tub, lawv yuav tsum tau tawm dag zog tswj ntshav qabzib hauv cov ntshav, cov lus qhia zoo ib yam rau cov poj niam uas npaj xeeb menyuam.

Qhov kev xav tau rau insulin feem ntau poob qis hauv thawj peb lub hlis thaum cev xeeb tub thiab maj mam nce ntxiv hauv qib thib ob thiab thib peb.

Tom qab yug menyuam, xav tau cov tshuaj insulin, raws li txoj cai, rov qab sai sai rau qib uas tau pom ua ntej muaj menyuam hauv plab.

Kuj tseem tsis muaj kev txwv rau kev siv cov tshuaj Protafan® NM lub sijhawm pub niam mis. Ua cov tshuaj insulin rau cov poj niam lub sijhawm pub niam mis yog tsis muaj kev phom sij rau tus menyuam. Txawm li cas los xij, nws yuav tsim nyog kho qhov tshuaj ntau npaum li cas ntawm cov tshuaj Protafan® NM thiab / lossis kev noj haus.

Kev cuam tshuam nrog lwm yam tshuaj

Muaj ntau tus yeeb tshuaj uas cuam tshuam rau kev xav tau cov tshuaj insulin.

Hypoglycemic nyhuv ntawm insulin txhim khu qhov ncauj hypoglycemic agents, monoamine oxidase inhibitors, angiotensin converting enzyme inhibitors, carbonic anhydrase inhibitors, xim beta-blockers, bromocriptine, sulfonamides, anabolic steroids, tetracyclines, clofibrate, ketoconazole, mebendazole, pyridoxine, theophylline, cyclophosphamide, fenfluramine, tshuaj lithium salicylates Cov.

Cov nyhuv hauv lub ntsej muag ntawm insulin tsis muaj zog los ntawm kev tiv thaiv hauv qhov ncauj, glucocorticosteroids, cov thyroid hormones, thiazide diuretics, heparin, tricyclic antidepressants, sympathomimetics, kev loj hlob hormone (somatropin), danazol, clonidine, qeeb calcium channel blockers, diafenin, diazoxide.

Beta-blockers tuaj yeem npog cov tsos mob ntawm kev mob ntshav qab zib thiab kev ua kom rov qab sai sai tom qab kev txo ntshav qis.

Octreotide / lanreotide tuaj yeem nce ntxiv thiab txo qis qhov xav tau ntawm lub cev.

Cawv yuav ua kom cov ntshav qis los tsis txaus. Incompatibility

Insulin kev ncua yuav tsum tsis muab ntxiv rau cov kev daws teeb meem.

Daim ntawv thov nta

Qhov tsis txaus siv ib koob tshuaj lossis kev tsis ua tiav ntawm kev kho mob, tshwj xeeb tshaj yog nrog hom 1 mob ntshav qab zib mellitus, tuaj yeem ua rau kev loj hlob ntawm hyperglycemia.

Raws li txoj cai, thawj cov tsos mob ntawm hyperglycemia tshwm sim maj, dhau ob peb teev lossis hnub. Cov tsos mob ntawm hyperglycemia suav nrog kev nqhis dej, ntxiv tso zis, xeev ntuav, ntuav, nkees, liab thiab tawv nqaij ntawm daim tawv nqaij, lub qhov ncauj qhuav, tsis qab los noj mov, thiab cov tsos ntawm cov ntxhiab tsw phem hauv cov pa tawm. Yog tias tsis muaj kev kho mob uas tsim nyog, hyperglycemia hauv cov neeg mob uas muaj ntshav qab zib hom 1 tuaj yeem ua rau ketoacidosis mob ntshav qab zib, uas yog ib qho mob uas yuav ua rau tuag taus.

Kev mob ntshav qab zib tsawg tuaj yeem tsim yog tias muaj cov tshuaj insulin ntau dhau los ua rau cuam tshuam nrog tus neeg mob cov kev xav tau.

Noj zaub mov los sis ua tej yam qoj ib ce tsis txaus yuav ua rau lub qog ntshav qab zib.

Tom qab them nyiaj rau cov pluas noj carbohydrate, piv txwv li, thaum lub sij hawm sib zog kho insulin, cov neeg mob cov tsos mob uas tshwm sim rau lawv tej zaum yuav hloov - cov mob ntshav sai ua ntej, hais txog qhov twg cov neeg mob yuav tsum tau qhia. Cov paib ceeb toom ib txwm yuav ploj thaum muaj ntshav qab zib ntev.

Hloov chaw ntawm cov neeg mob mus rau lwm hom tshuaj insulin lossis insulin ntawm lwm qhov chaw tsim khoom yuav tsum tau ua nyob rau hauv kev saib xyuas kev kho mob nkaus xwb. Yog tias koj hloov lub siab, cov chaw tsim khoom, hom, hom (tib neeg insulin, kev sib piv ntawm tib neeg cov insulin) thiab / lossis cov qauv kev tsim khoom, koj yuav tsum hloov cov koob tshuaj insulin. Cov neeg mob uas tau txais kev kho mob nrog Protafan® NM tej zaum yuav tau hloov koob tshuaj lossis nce ntau zaus ntawm kev txhaj tshuaj piv rau kev siv tshuaj insulin uas tau siv yav dhau los. Yog tias kev hloov kho koob tshuaj yog tsim nyog thaum hloov cov neeg mob mus rau kev kho mob nrog Protafan® NM, qhov no tuaj yeem ua tiav nrog kev qhia ntawm thawj koob tshuaj lossis hauv thawj lub lis piam lossis hli ntawm kev kho.

Ib yam li lwm cov tshuaj insulin, cov tshuaj tiv thaiv tuaj yeem tsim kho ntawm qhov chaw txhaj tshuaj, uas pom los ntawm qhov mob, liab liab, ua xua, mob o, hematoma, o thiab khaus. Hloov pauv chaw txhaj tshuaj ntawm tib thaj chaw ib puag ncig yuav pab txo cov tsos mob lossis tiv thaiv kev txhim kho ntawm cov kev cuam tshuam no. Cov kev tawm tsam feem ntau ploj li ntawm ob peb hnub mus rau ntau lub lis piam. Tsawg tsawg zaus, tsis muaj kev tiv thaiv ntawm Protafan® NM yog qhov tsim nyog vim tias cov tshuaj tiv thaiv nyob ntawm thaj chaw txhaj tshuaj.

Ua ntej taug kev nrog kev hloov chaw ntawm lub sijhawm, tus neeg mob yuav tsum sab laj nrog lawv tus kws kho mob, vim tias hloov chaw ntawm lub sijhawm txhais tau tias tus neeg mob yuav tsum noj thiab siv tshuaj insulin rau lwm lub sijhawm. Kev siv tshuaj insulin tsis tuaj yeem siv hauv cov twj insulin.

Kev siv tshuaj ib txhij ntawm thiazolidinedione pab pawg thiab tshuaj insulin npaj

Cov kab mob ntawm kev loj hlob ntawm kev mob plawv ntev tau qhia tawm hauv kev kho mob ntawm cov neeg mob thiazolidinediones sib xyaw nrog kev npaj tshuaj insulin, tshwj xeeb tshaj yog tias cov neeg mob no muaj kev pheej hmoo rau kev loj hlob ntawm lub plawv tsis ua haujlwm. Qhov tseeb no yuav tsum raug coj los txiav txim siab thaum sau ntawv kho kev sib xyaw nrog thiazolidinediones thiab tshuaj insulin rau cov neeg mob. Nrog rau kev teem sijhawm ntawm txoj kev kho ua ke, nws yog ib qho tsim nyog yuav tsum ua kev soj ntsuam kev kho mob ntawm cov neeg mob kom paub cov cim thiab cov tsos mob ntawm kev mob plawv tsis xwm yeem, hnyav nce thiab muaj cov edema. Yog hais tias cov tsos mob ntawm lub plawv tsis zoo nyob rau hauv cov neeg mob, kev kho mob nrog thiazolidinediones yuav tsum tau tsum txiav.

Kev cuam tshuam rau lub peev xwm tsav tsheb thiab ua haujlwm nrog cov txheej txheem

Lub peev xwm ntawm cov neeg mob kom pom tseeb thiab tus nqi tshuaj tiv thaiv tej zaum yuav ua rau lub sijhawm tsis muaj ntshav qab zib, uas tuaj yeem tsim kev puas tsuaj nyob rau hauv cov xwm txheej uas cov peev xwm no tsim nyog tshwj xeeb (piv txwv li, thaum tsav tsheb lossis ua haujlwm nrog cov tshuab thiab tshuab). Cov neeg mob yuav tsum qhia rau kev ntsuas kom tiv thaiv kev txhim kho hypoglycemia thaum tsav tsheb. Qhov no yog qhov tshwj xeeb tshaj yog rau cov neeg mob uas tsis muaj los yog ploj zuj zus ntawm cov tshwm sim ntawm kev muaj ntshav qab zib lossis kev txom nyem los ntawm kev pheej muaj ntshav tsis txaus. Hauv cov xwm txheej no, kev tsim nyog ntawm kev tsav tsheb thiab ua cov haujlwm no yuav tsum raug txiav txim siab.

Cia rau cov neeg mob

Khaws ntawm qhov kub ntawm 2 ° C txog 8 ° C (hauv tub yees), tab sis tsis txhob nyob ze ntawm lub taub yees txias. Tsis khov.

Khaws lub raj mis tso rau hauv lub thawv ntawv los tiv thaiv los ntawm lub teeb.

Rau lub raj mis qhib: tsis txhob cia hauv tub yees. Khaws ntawm qhov kub thiab txias tsis tshaj 25 ° C rau 6 lub lis piam.

Protafan® NM yuav tsum muaj kev tiv thaiv los ntawm tshav kub ntau dhau thiab lub teeb. Khaws tsis ncav cuag ntawm cov menyuam yaus.