Insulin Rapid: lub sijhawm ntawm kev ua thiab cov lus qhia rau kev siv

Cov tshuaj insulin txo cov concentration ntawm cov piam thaj hauv cov ntshav, txhawb cov teebmeem anabolic thiab txo cov teebmeem catabolic. Nws nce cov piam thaj hauv kev thauj mus rau hauv cov hlwb thiab kev tsim cov glycogen hauv cov leeg thiab daim siab, txhim kho kev siv pyruvate, thiab inhibits glycogenolysis thiab glyconeogenesis. Cov tshuaj insulin nce lipogenesis nyob rau hauv daim siab thiab adipose ntaub so ntswg thiab inhibits lipolysis. Txhawb nqa qhov khiav ntawm cov amino acids rau hauv cov hlwb thiab kev sib sau ntawm cov protein, ua kom cov pa roj ntau ntau ntxiv rau hauv lub cell.

Insuman ® Rapid GT yog qhov insulin nrog kev pib sai thiab lub sijhawm ua haujlwm luv. Tom qab cov thawj coj sc, cov nyhuv hypoglycemic tshwm sim li ntawm 30 feeb, nce mus txog qhov siab kawg hauv 1-4 teev, tseem mob siab rau 7-9 teev.

Sau cov analogues

Ua tib zoo mloog! Cov ntawv teev npe muaj cov lus txhais sib txawv rau Insuman Rapid GT, uas muaj cov qauv sib xws, yog li koj tuaj yeem xaiv hloov tus kheej, xav txog daim ntawv thiab ntau npaum li cas ntawm cov tshuaj uas kws kho mob sau los ntawm koj tus kws kho mob. Muab kev nyiam rau cov tuam ntxhab los ntawm Asmeskas, Nyiv, Western Europe, thiab cov tuam txhab lag luam zoo los ntawm Eastern Europe: Krka, Gideon Richter, Actavis, Aegis, Lek, Hexal, Teva, Zentiva.

Kaum ib cov qhua tau qhia txog cov nqi noj haus txhua hnub

Kuv yuav tsum tau noj Insuman Rapid GT ntau npaum li cas?
Cov neeg teb feem ntau yuav tau haus cov tshuaj no ib hnub 3 zaug. Daim ntawv tshaj tawm qhia tias pes tsawg tus neeg teb ntxiv siv cov tshuaj no.

Ib tus qhua qhua tau tshaj tawm txog kev teem caij

Lub sijhawm twg zoo dua los noj Insuman Rapid GT: ntawm lub plab khoob, ua ntej, tom qab lossis nrog zaub mov noj?
Cov neeg siv ntawm thaj chaw feem ntau tau tshaj tawm tias lawv noj cov tshuaj no ua ntej noj mov. Txawm li cas los xij, tus kws kho mob yuav qhia lwm lub sijhawm. Daim ntawv tshaj tawm qhia tias thaum tus neeg mob xam phaj tas cov tshuaj noj.

Cov yam ntxwv dav dav. Muaj pes tsawg leeg:

Cov khoom siv nquag: tib neeg cov insulin (100% solulin tib neeg cov kua dej) - 3,571 mg (100 IU),
kev zam: metacresol (m-cresol), sodium dihydrogen phosphate dihydrate, glycerol (85%), sodium hydroxide (siv los kho pH), hydrochloric acid (siv los kho pH), dej rau kev txhaj tshuaj.
Cov lus piav qhia: ntshiab, tsis muaj kua.

Cov yam ntxwv Pharmacological:

Cov Tshuaj Hauv Tshuaj Insuman® Rapid GT muaj cov tshuaj insulin zoo ib yam hauv cov qauv rau tib neeg insulin thiab tau los ntawm kev tsim kho caj ces siv K12 lim ntshav E. Coli. Tus txheej txheem ntawm kev ua ntawm insulin:
- txo qhov concentration ntawm cov piam thaj hauv cov ntshav, txhawb cov teebmeem anabolic thiab txo cov teebmeem catabolic,
- nce hloov chaw ntawm cov kua nplaum mus rau hauv lub hlwb thiab kev tsim cov glycogen hauv cov leeg thiab mob siab thiab txhim kho kev siv pyruvate, inhibits glycogenolysis thiab glyconeogenesis,
- nce lipogenesis nyob rau hauv daim siab thiab adipose nqaij thiab inhibits lipolysis,
- txhawb cov ndlwg ntawm cov amino acids rau hauv hlwb thiab protein synthesis,
- nce cov vitamins ntawm lub cev mus rau hauv lub hlwb.
Insuman® Rapid GT yog ib qho tshuaj insulin nrog kev pib ua haujlwm thiab lub sijhawm luv luv. Tom qab tswj hwm subcutaneous, cov nyhuv hypoglycemic tshwm sim hauv 30 feeb thiab nce mus txog qhov siab tshaj plaws hauv 1-4 teev. Cov nyhuv ntev li 7-9 teev.

Kev taw qhia rau kev siv:

Mob ntshav qab zib mellitus xav tau kev kho mob insulin.
- Kev kho mob ntshav qab zib tsis xeev plab thiab.
- Kev ua tiav ntawm cov nyiaj metabolic rau cov neeg mob ntshav qab zib mellitus thaum phais mob (ua ntej kev phais mob, thaum phais thiab tom qab lub sijhawm txiav txim siab).

Tseem Ceeb! Txheeb xyuas txoj kev kho mob

Muab thiab kev coj:

Kev xaiv cov koob tshuaj insulin hauv ib tus neeg mob yog nqa los ntawm tus kws kho mob ib tus zuj zus raws li kev noj haus, theem kev ua haujlwm thiab kev ua neej. Qhov kev txhaj tshuaj ntawm cov tshuaj insulin yog txiav txim siab raws li theem ntawm cov piam thaj hauv cov ntshav, nrog rau qhov kev npaj ua ntej ntawm kev qoj ib ce thiab lub xeev ntawm carbohydrate metabolism. Nyeem ntxiv txog kev suav tshuaj rau hom 1 thiab ntshav qab zib hom 2 twg. Kev kho tshuaj Insulin yuav tsum muaj kev paub tus kheej rau tus neeg mob. Tus kws kho mob yuav tsum muab cov lus qhia uas yuav tsum tau txiav txim siab npaum li cas los txiav txim siab txog qib qab zib hauv cov ntshav thiab, tejzaum nws, hauv cov zis, thiab tseem yuav muab cov lus qhia tsim nyog rau thaum muaj kev hloov pauv hauv kev noj zaub mov noj lossis hauv kev kho mob ntawm insulin.
Qhov nruab nrab txhua hnub koob tshuaj insulin yog los ntawm 0.5 txog 1.0 ME ib kg ntawm lub cev qhov hnyav ntawm tus neeg mob, thiab 40-60% ntawm qhov koob tshuaj poob rau tib neeg insulin nrog kev ua ntev.
Thaum hloov los ntawm tsiaj cov tshuaj insulin rau tib neeg cov tshuaj insulin, yuav tsum tau txhaj tshuaj insulin tsawg dua. Kev hloov pauv ntawm lwm yam tshuaj insulin rau cov tshuaj no tsuas yog ua los ntawm kev saib xyuas kev noj qab haus huv xwb. Tshwj xeeb kev soj ntsuam ntau zaus ntawm lub xeev ntawm cov roj av metabolism hauv yog qhov tsim nyog hauv thawj lub lis piam tom qab xws li kev hloov pauv.
Insuman Rapid GT feem ntau yog tswj xyuas kom tob subcutaneously 15-20 feeb ua ntej noj mov. Intramuscular thawj coj ntawm cov tshuaj yog tso cai. Qhov chaw txhaj tshuaj yuav tsum tau hloov txhua zaus. Hloov thaj chaw txhaj tshuaj (piv txwv li, los ntawm lub plab mus rau ncej puab) yuav tsum tau ua tsuas yog tom qab sab laj nrog kws kho mob.
Insuman Rapid GT tuaj yeem muab tshuaj rau hauv kev kho mob ntawm hyperglycemic coma thiab ketoacidosis, ntxiv rau ua tiav cov nyiaj metabolic them ua ntej, rau siab- thiab tom qab lub sijhawm nyob hauv cov neeg mob ntshav qab zib mellitus.
Insuman Rapid GT tsis yog siv rau hauv ntau hom tshuaj insulin (suav nrog cov uas siv cog), qhov twg ib qho tshuaj pleev silicone.
Tsis txhob sib xyaw Insuman Rapid GT nrog cov kua dej ntawm cov tshuaj sib txawv (piv txwv li 40 IU / ml thiab 100 IU / ml), nrog insulin ntawm tsiaj keeb kwm lossis lwm yam tshuaj. Tsuas yog siv cov ntshiab, tsis muaj kob ntawm Insuman Rapid GT cov kev daws teeb meem uas tsis muaj qhov pom ntawm qhov tsis txaus ntseeg.
Nws yuav tsum nco ntsoov tias kev tsim nyog ntawm cov tshuaj insulin hauv lub vial yog 100 IU / ml, yog li koj tsuas yog yuav tsum tau siv cov yas koob txhaj tshuaj tsim rau qhov no cov tshuaj insulin. Cov koob txhaj tshuaj yuav tsum tsis txhob muaj lwm yam tshuaj lossis nws cov seem.
Ua ntej thawj zaug teeb tsa insulin los ntawm vial, tshem lub hau yas (lub xub ntiag ntawm lub hau yog pov thawj ntawm lub vial tsis tau qhib). Txoj kev txhaj tshuaj yuav tsum yog cov pob tshab thiab tsis muaj xim.
Ua ntej cov tshuaj insulin tawm ntawm lub vial, qhov ntim ntawm huab cua sib npaug ntawm cov tshuaj tua kab mob ntawm insulin yog nqus rau hauv cov koob txhaj tshuaj thiab txhaj rau hauv lub thauv (tsis yog kua. Tom qab cov thauv nrog lub koob txhaj tshuaj yog ntxeev tiaj nrog lub koob txhaj tshuaj thiab qhov yuav tsum tau siv cov tshuaj insulin. Ua ntej txhaj tshuaj, tshem cov pa npuas los ntawm lub koob txhaj tshuaj.
Ib daim ntawm daim tawv nqaij yog coj ntawm qhov chaw txhaj tshuaj, ib rab koob raug tso rau hauv qab daim tawv nqaij, thiab cov tshuaj insulin yog maj mam txhaj. Tom qab txhaj tshuaj, rab koob tau maj mam tawm thiab qhov chaw txhaj tshuaj yog nias nrog paj rwb pas rwb mus ntev li ob peb feeb. Hnub tim ntawm thawj cov khoom siv insulin los ntawm lub thauv yuav tsum sau rau ntawm daim ntawv lo ntawm lub vial.
Tom qab qhib lub hwj tuaj yeem khaws cia ntawm qhov kub tsis dhau + 25 ° C rau 4 lub lis piam hauv qhov chaw tiv thaiv los ntawm lub teeb thiab cua sov.

Daim Ntawv Thov Nta:

Yog tias tsis muaj cov tshuaj glycemic tswj lossis lub siab nyiam rau lub sijhawm ntau dhau ntawm hyper- lossis hypoglycemia, ua ntej txiav txim siab yuav kho cov tshuaj insulin, nco ntsoov soj ntsuam cov tshuaj noj ntawm insulin thawj coj, nco ntsoov tias insulin raug txhaj rau hauv thaj chaw pom zoo, xyuas qhov tseeb ntawm cov txheej txheem kev txhaj tshuaj thiab tag nrho lwm yam uas yuav cuam tshuam rau cov nyhuv ntawm insulin.
Txij li thaum tswj hwm kev sib txig ntawm ntau cov tshuaj (saib hauv "Kev Sib Tham Nrog Lwm Cov Tshuaj") tuaj yeem ua kom tsis muaj zog lossis txhim kho qhov tsis zoo ntawm cov tshuaj Insuman® Rapid GT, tsis muaj lwm yam tshuaj yuav tsum tau noj thaum nws siv yam tsis muaj kev tso cai tshwj xeeb ntawm tus kws kho mob.
Kev mob ntshav qab zib tsawg tshwm sim yog tias cov koob tshuaj insulin ntau dua qhov xav tau. Txoj kev pheej hmoo ntawm kev txhim kho hypoglycemia yog qhov siab thaum pib ntawm kev kho tshuaj insulin, thaum hloov mus rau lwm txoj kev npaj tshuaj insulin, hauv cov neeg mob uas tsis muaj kev saib xyuas qis ntawm cov piam thaj hauv cov ntshav.
Ib yam li txhua tus insulins, tshwj xeeb yuav tsum tau saib xyuas thiab soj ntsuam ntshav qabzib ntau hauv cov neeg mob uas tus mob ntshav qab zib tsawg yuav muaj qhov tshwj xeeb hauv kev kho mob, xws li cov neeg mob uas mob hnyav ntawm lub plawv lossis mob hlab ntsha hlwb (kev pheej hmoo ntawm lub plawv lossis mob hlwb ntawm hypoglycemia), pom zoo. , zoo ib yam nkaus li hauv cov neeg mob uas muaj kev tu ncua sai, tshwj xeeb tshaj yog tias lawv tsis tau yauv mus ua photocoagulation (kho laser), vim tias lawv muaj kev pheej hmoo ntawm amaurosis (hloov tag nrho) qhov muag tsis pom) nrog kev txhim kho hypoglycemia.
Muaj qee yam kev mob tshwm sim thiab cov tsos mob uas yuav tsum qhia rau tus neeg mob lossis lwm tus txog kev txhim kho hypoglycemia. Cov no suav nrog: kev tawm hws ntau dhau, noo noo ntawm daim tawv nqaij, lub plawv ua suab tsis sib xws, ntshav nce siab, mob hauv siab, ntxhov siab, tshaib plab, nkees nkees, ntshai, ua tsis taus pa, coj tus cwj pwm txawv, ntxhov siab, mob caj dab hauv lub qhov ncauj thiab ib ncig lub qhov ncauj, pallor ntawm daim tawv nqaij , kev ua tsis tau zoo ntawm kev txav, nrog rau kev hloov chaw mob ntawm lub cev (tsis hnov ​​lus thiab tsis pom kev, cov kab mob tuag tes tuag taw) thiab cov kev hnov ​​tsis meej. Nrog rau qhov ua kom cov piam thaj ntau zuj zus, tus neeg mob yuav plam nws tus kheej thiab txawm tias nws tsis nco qab. Hauv cov xwm txheej zoo li no, kev saib xyuas txias thiab noo noo ntawm daim tawv nqaij, thiab kuj tseem tuaj yeem tshwm sim.
Yog li, txhua tus neeg mob ntshav qab zib uas tau txais insulin yuav tsum kawm kom paub txog cov tsos mob uas yog tus yam ntxwv mob qog ntshav qab zib. Cov neeg mob uas niaj zaus saib xyuas kom cov ntshav qabzib hauv cov ntshav yuav tsis muaj ntshav qab zib tsawg. Tus neeg mob nws tus kheej tuaj yeem kho qhov txo qis cov piam thaj hauv kev saib xyuas hauv nws cov ntshav los ntawm kev noj cov suab thaj los yog cov zaub mov uas muaj cov carbohydrates ntau. Rau lub hom phiaj no, tus neeg mob yuav tsum ib txwm muaj 20 g suab thaj nrog nws. Nyob rau hauv cov mob hnyav dua ntawm cov ntshav qog ntshav qab zib, kev txhaj tshuaj ntshav qab zib ntawm glucagon yog qhia (uas tuaj yeem ua los ntawm tus kws kho mob lossis cov neeg ua haujlwm tu mob). Tom qab txhim kho kom zoo txaus, tus neeg mob yuav tsum noj. Yog tias hypoglycemia tsis tuaj yeem raug tshem tawm sai, ces tus kws kho mob yuav tsum tau hu rau tam sim ntawd. Nws yog ib qho tsim nyog yuav tsum tau qhia rau tus kws kho mob tam sim ntawd txog kev txhim kho hypoglycemia txhawm rau kom nws txiav txim siab ntawm qhov xav tau los kho qhov tshuaj ntawm cov tshuaj insulin.Ua tsis tiav raws li kev noj haus, hla kev txhaj tshuaj insulin, kev xav tau insulin ntau ntxiv los ntawm kev kis tus kabmob lossis lwm yam kabmob, thiab kev qoj ib ce txo qis tuaj yeem ua rau muaj ntshav qabzib ntau ntxiv (hyperglycemia), tej zaum muaj qhov nce ntawm ketone lub cev hauv cov ntshav (ketoacidosis). Ketoacidosis tuaj yeem tshwm sim hauv ob peb teev lossis ob peb hnub. Nyob rau ntawm thawj cov tsos mob (nqhis dej, tso zis heev, tsis qab los, nkees, tawv nqaij qhuav, nqus thiab ua pa sai, cov ntsiab lus ntawm acetone thiab qabzib nyob hauv cov zis), yuav tsum tau muaj kev kho mob sai sai.
Thaum hloov tus kws kho mob (piv txwv li, thaum mus pw hauv tsev kho mob vim muaj kev huam yuaj, mob thaum so haujlwm), tus neeg mob yuav tsum qhia tus kws kho mob tias nws muaj dab tsi.
Cov neeg mob yuav tsum raug ceeb toom txog kev mob thaum lawv yuav hloov, tsis tshua hais lus lossis tsis muaj tsos mob ceeb toom txog kev txhim kho hypoglycemia, piv txwv:
- nrog kev txhim kho tseem ceeb hauv kev tswj glycemic,
- nrog kev paub zuj zus kev txhim kho hypoglycemia,
- hauv cov neeg laus laus,
- hauv cov neeg mob lub cev tsis hlwb,
- hauv cov neeg mob uas muaj keeb kwm mob ntshav qab zib ntev,
- hauv cov neeg mob tib lub sijhawm tau txais kev kho mob nrog qee yam tshuaj (saib Ntu “Kev cuam tshuam nrog lwm cov tshuaj). Cov xwm txheej zoo li no tuaj yeem ua rau muaj kev mob ntshav qab zib ntau (thiab poob nrog tsis nco qab lawm) ua ntej tus neeg mob paub tseeb tias nws tab tom xyaum kho tus mob ntshav qab zib tsawg.
Yog tias ib txwm los yog qis dua glycosylated hemoglobin qhov tseem ceeb tau pom, yuav tsum xav txog kev tsim kho dua, tsis muaj kev paub txog (tshwj xeeb tshaj yog nyob ntawm nocturnal) lub sijhawm ntawm hypoglycemia.
Txo txo ​​qhov kev pheej hmoo ntawm hypoglycemia, tus neeg mob yuav tsum nruj ua raws li cov kev noj tshuaj thiab cov khoom noj khoom haus zoo, tswj cov tshuaj insulin kom raug, thiab ceeb toom cov tsos mob ntawm kev txhim kho hypoglycemia.
Qhov tseeb uas ua rau kom lub siab xav txog qhov kev txhim kho hypoglycemia xav tau kev saib xyuas kom zoo thiab tej zaum yuav tsum muaj kev kho kom haum. Tej yam no suav nrog:
- hloov hauv thaj tsam ntawm kev tswj hwm ntawm insulin,
- muaj kev rhiab ntxiv rau cov tshuaj insulin (piv txwv, tshem tawm cov kev ntxhov siab),
- txawv txawv (nce lossis ntev zog kev ua haujlwm lub cev),
- intercurrent pathology (ntuav,),
- kev noj zaub mov tsis txaus,
- yauv noj mov,
- haus dej haus cawv,
- qee qhov mob tsis muaj qhov xaus ntawm cov kab mob endocrine (xws li tsis txaus ntawm anterior pituitary lossis tsis txaus ntawm adrenal cortex),
- Kev siv qee cov tshuaj (tib ntu kev sib txuam nrog lwm cov tshuaj "). Cov kab mob sib kis
Hauv cov kab mob sib kis, yuav tsum muaj kev tswj kev zom zaub mov ntau. Feem ntau, tso zis rau kuaj pom ntawm ketone lub cev raug qhia, thiab kev kho cov tshuaj insulin feem ntau tsim nyog. Qhov kev xav tau rau insulin feem ntau nce. Cov neeg mob ntshav qab zib hom 1 yuav tsum txuas ntxiv haus tsawg kawg ib qho me me ntawm carbohydrates tsis tu ncua, txawm tias lawv tsuas tuaj yeem noj me me ntawm cov zaub mov lossis yog tias lawv muaj, thiab lawv yuav tsum tsis txhob tso tshuaj insulin ntxiv. Cov tshuaj tiv thaiv kab mob hla
Hauv qhov ncaj ncees ntawm cov neeg mob uas muaj lub siab ntev mus rau insulin ntawm tsiaj keeb kwm, nws yog qhov nyuaj rau hloov mus rau tib neeg insulin vim tus ntoo khaub lig-tiv thaiv kab mob ntawm tib neeg insulin thiab insulin ntawm tsiaj keeb kwm. Nrog rau kev nkag siab ntau ntxiv ntawm tus neeg mob rau insulin ntawm tsiaj keeb kwm, nrog rau m-cresol, kev kam rau ntawm cov tshuaj Insuman® Rapid GT yuav tsum raug soj ntsuam hauv qhov chaw kho mob siv cov kev kuaj mob intradermal.Yog tias thaum lub sijhawm kuaj ntshav tsis haum rau tib neeg cov tshuaj insulin (kuaj tam sim ntawd, xws li Arthus), tom qab ntawd yuav tsum tau kho ntxiv nyob rau hauv kev saib xyuas mob.
Cuam tshuam rau kev muaj peev xwm tsav tsheb lossis lwm yam txheej txheem
Tus neeg mob lub peev xwm mloog tau ceev thiab qhov ceev ntawm psychomotor cov tshuaj tiv thaiv tuaj yeem ua rau tsis muaj txiaj ntsig vim yog qhov mob ntshav qab zib lossis, lossis qhov tshwm sim ntawm cov teeb meem tsis pom kev. Qhov no tuaj yeem ua rau muaj kev pheej hmoo nyob hauv cov xwm txheej uas cov peev xwm no tseem ceeb (tsav tsheb lossis lwm yam).
Cov neeg mob yuav tsum tau qhia rau kom ceev faj thiab zam kom tsis txhob mob ntshav qab zib thaum tsav tsheb. Qhov no yog qhov tshwj xeeb tshaj yog nyob rau hauv cov neeg mob uas tau txo qis lossis tsis paub txog cov tsos mob tshwm sim uas qhia kev txhim kho ntawm lub qog ntshav qab zib, lossis muaj kev pheej hmoo sai ntawm cov ntshav qog ntshav qab zib. Hauv cov neeg mob zoo li no, lo lus nug ntawm kev muaj peev xwm tsav lawv nrog tsheb lossis lwm cov txheej txheem yuav tsum tau txiav txim siab ib leeg.

Phiv los sis:

Kev mob ntshav qab zib, feem ntau cov kev mob tshwm sim, tuaj yeem txhim kho yog tias cov koob tshuaj insulin tau tshaj li qhov xav tau ntawm nws (saib "Kev Ceeb Toom thiab cov lus qhia tshwj xeeb").
Kev hloov pauv hauv cov ntshav qab zib tuaj yeem ua rau lub ntsej muag luv-cuam tshuam. Tsis tas li, tshwj xeeb nrog kev kho mob insulin ntau, qhov luv-luv zuj zus ntawm chav kawm yog qhov ua tau. Hauv cov neeg mob uas muaj kev tu ncua sai, tsis tas siv cov kev kho mob laser, kev mob ntshav qab zib ntau yam tuaj yeem ua rau dig muag.
Qee zaum, ntawm qhov chaw txhaj tshuaj, hypertrophy ntawm adipose cov ntaub so ntswg yuav tshwm sim, uas tuaj yeem zam los ntawm qhov hloov tas mus li qhov chaw txhaj tshuaj. Muaj qee zaus, me liab yuav tshwm sim ntawm qhov chaw txhaj tshuaj, ploj nrog kev kho txuas ntxiv. Yog tias qhov mob erythema tseem ceeb tau tsim, nrog nws khaus thiab o, thiab nws kis tau nrawm dhau ntawm qhov chaw txhaj tshuaj, nrog rau lwm qhov tsis zoo cuam tshuam rau cov tshuaj ntawm cov tshuaj (insulin, m-cresol), nws yog qhov yuav tsum tau hais qhia rau tus kws kho mob, xws li qee kis cov kev coj ua zoo li no tuaj yeem tsim kev hem thawj rau tus neeg mob lub neej. Kev tsis haum ntshav siab yog qhov tsawg. Lawv tuaj yeem ua ke nrog kev txhim kho ntawm mob hlwb, mob ntsws, mob ntshav ntws poob thiab tsis tshua nco qab ua kom poob siab. Kev tsis haum lub siab xav tau kev hloov kho tam sim no hauv kev kho mob txuas ntxiv nrog kev siv tshuaj insulin thiab kev saws los ntawm kev ntsuas thaum tsim nyog.
Tej zaum qhov tsim cov tshuaj tiv thaiv rau cov tshuaj insulin, uas tej zaum yuav xav tau kev kho tshuaj ntawm cov tshuaj insulin. Nws tseem muaj peev xwm tso sodium rov qab los ntawm qhov o ntawm cov ntaub so ntswg, tshwj xeeb tshaj yog tom qab kev kawm kho mob ntxiv nrog cov tshuaj insulin.
Nrog txoj kev mob ntshav qab zib kom tsawg, kev txhim kho (mob hnyav ntawm cov hlab plawv) lossis kev txhim kho ntawm cov hlab hlwb txhaws yog qhov ua tau.
Vim tias muaj qee yam kev mob tshwm sim tuaj yeem ua rau muaj kev phom sij txog lub neej, nws yog qhov yuav tsum tau qhia rau tus kws kho mob uas tuaj koom thaum lawv tshwm sim.
Yog tias koj pom cov kev mob tshwm sim, thov sab laj nrog koj tus kws kho mob!

Kev cuam tshuam nrog lwm cov tshuaj:

Co-administration nrog hypoglycemic tus neeg sawv cev rau kev tswj hwm ntawm qhov ncauj, angiotensin-hloov enzyme inhibitors, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors,
pentoxifylline, propoxyphene, salicylates, amphetamine, anabolic steroids thiab txiv neej poj niam txiv neej cov tshuaj hormones, cybenzoline, cyclophosphamide, fenfluramine, guanethidine, ifosfamide, phenoxybenzamine, phentolamine, somatostatin thiab tetroformofilamine, tetroformon, sulfate sulfon, sulfate sulfon kev txhim kho ntawm hypoglycemia.
Lub neej coj siv corticotropin, corticosteroids, danazol, diazoxide, diuretics, glucagon, Isoniazid, estrogens thiab progestogens (xws li tam sim no nyob rau hauv ib tug neej coj contraceptive), phenothiazine derivatives, kev loj hlob lawm, sympathomimetic tshuaj (e.g., epinephrine, salbutamol, terbutaline), cov thyroid hormones, barbiturates, nicotinic acid, phenolphthalein, phenytoin derivatives, doxazosin tuaj yeem txo cov nyhuv hypoglycemic ntawm insulin.
Beta-blockers, clonidine, lithium ntsev tuaj yeem yog potentiate lossis ua kom cov ntshav tsis muaj zog ntawm insulin.
Nrog ethanol
Ethanol tuaj yeem yog potentiate lossis ua rau cov ntshav tsis muaj zog ntawm insulin. Kev noj tshuaj Ethanol tuaj yeem ua rau cov ntshav qabzib lossis txo qis cov ntshav qabzib dhau mus rau qib txaus ntshai. Kev noj tshuaj Ethanol hauv cov neeg mob uas tau txais insulin yog txo. Tso cai rau haus dej haus cawv ntau npaum yuav tsum yog txiav txim los ntawm koj tus kws kho mob. Nrog pentamidine
Nrog rau kev tswj hwm tib lub sijhawm, kev txhim kho hypoglycemia yog qhov ua tau, uas tuaj yeem qee zaum tig mus rau hauv hyperglycemia.
Thaum ua ke nrog cov neeg mob sympatholytic, xws li beta-blockers, clonidine, guanethidine thiab reserpine, qhov ua kom tsis muaj zog lossis ua kom tiav ntawm cov tsos mob ntawm tus mob reflex (nyob rau hauv teb rau hypoglycemia) kev ua kom zoo ntawm cov leeg hlwb muaj peev xwm ua tau.

Cov Tshuaj Tiv Thaiv:

Kev ntshav siab.
- Kev siv tshuaj tiv thaiv kab mob tsis txaus rau cov tshuaj insulin lossis rau qee yam ntawm cov tshuaj tiv thaiv cov tshuaj.
Yog tias koj muaj ib qho ntawm cov kabmob lossis cov xwm txheej no, nco ntsoov sab laj nrog koj tus kws kho mob ua ntej siv cov tshuaj. Nrog saib xyuas
- Thaum (nws muaj peev xwm txo qis qhov xav tau ntawm insulin vim tias txo qis hauv cov tshuaj insulin metabolism).
- Hauv cov neeg laus neeg mob (txoj kev ua haujlwm hauv lub raum tsawg zuj zus tuaj
ua rau txo qis hauv insulin qhov xav tau).
- Hauv cov neeg mob uas muaj mob hepatic txaus (qhov kev xav tau rau insulin tuaj yeem txo vim qhov txo qis hauv lub peev xwm gluconeogenesis thiab txo qis hauv cov tshuaj insulin metabolism).
- Hauv cov neeg mob uas muaj mob stonosis ntawm txoj hlab ntshav siab thiab txoj hlab ntshav ntawm lub cev ntau dua (cov ntshav lub cev tsis muaj zog yuav muaj qhov tshwj xeeb hauv kev kho mob, vim tias muaj kev pheej hmoo ntawm lub plawv lossis mob hlwb ntau dua ntawm cov ntshav qab zib).
- Hauv cov neeg mob uas muaj kev tu ncua ntau dua, tshwj xeeb tshaj yog cov uas tsis tau txais kev kho mob nrog photocoagulation (kho laser), vim tias lawv muaj kev pheej hmoo ntawm amaurosis dhau los nrog cov hypoglycemia tiav - ua tiav kev dig muag.
- Hauv cov neeg mob uas muaj cov kabmob sib kis (txij li cov kabmob sib kis feem ntau xav tau cov tshuaj insulin).
Yog tias koj muaj ib qho ntawm cov kabmob lossis cov xwm txheej no, nco ntsoov sab laj nrog koj tus kws kho mob ua ntej siv cov tshuaj. Cev xeeb tub thiab lactation
Kev kho mob nrog Insuman® Rapid GT thaum cev xeeb tub yuav tsum txuas ntxiv. Cov tshuaj Insulin tsis hla qhov chaw tiv thaiv. Kev tswj kom zoo ntawm kev tswj lub cev zom zaub mov thoob plaws lub cev xeeb tub yuav tsum muaj rau cov poj niam uas muaj ntshav qab zib ua ntej cev xeeb tub, lossis rau cov poj niam uas tau muaj tus mob ntshav qab zib tsis tsaug zog.
Qhov kev xav tau rau insulin thaum cev xeeb tub tuaj yeem txo qis hauv thawj peb lub hlis thaum cev xeeb tub thiab feem ntau nce nyob rau lub sijhawm thib ob thiab peb lub hlis thaum cev xeeb tub. Tam sim ntawd tom qab yug los, xav tau insulin tsawg dua (muaj kev pheej hmoo ntawm cov ntshav qog ntshav qab zib tsawg dua). Thaum cev xeeb tub thiab tshwj xeeb tshaj yog tom qab yug menyuam tas, yuav tsum ua tib zoo saib xyuas cov ntshav qabzib hauv cov ntshav.
Yog tias koj cev xeeb tub los yog npaj lub cev xeeb tub, nco ntsoov qhia koj tus kws kho mob.
Tsis muaj kev txwv dab tsi rau kev kho mob insulin thaum pub niam mis.
muaj, txawm li cas los xij, yuav tsum tau txhaj tshuaj insulin thiab kev noj haus kev noj zaub mov kom haum.

Noj ntau dhau

Cov tsos mob
Kev noj tshuaj insulin ntau dhau, xws li tswj cov tshuaj insulin ntau dhau piv rau cov zaub mov lossis lub zog noj, tuaj yeem ua rau lub sijhawm ntshav nce siab ntau thiab tuag taus.
Ntau zaus cov ntshav qog ua kom ntshav qis (tus neeg mob puas nco qab) tuaj yeem nres los ntawm kev noj zaub mov carbohydrates. Nws yog qhov yuav tsum tau kho lub koob tshuaj insulin, kev noj zaub mov thiab ua si lub cev.
Yuav muaj ntau yam teeb meem ntshav qab zib tsawg nrog kev hnov ​​qab, txiav tawm los yog mob hlwb tuaj yeem nres los ntawm kev siv tshuaj intramuscular lossis subcutaneous ntawm glucagon los yog kev tswj hwm cov tshuaj ntawm cov tshuaj dextrose. Hauv cov menyuam yaus, qhov ntau npaum li cas ntawm dextrose raug tswj hwm tau tsim raws li qhov ntsuas lub cev ntawm tus menyuam. Tom qab nce qhov kev txiav txim siab ntawm cov piam thaj hauv cov ntshav, yuav tsum tau txais kev txhawb nqa ntawm carbohydrates thiab kev soj ntsuam tej zaum yuav tsum tau ua, txij li tom qab pom tseeb soj ntsuam kev tshem tawm cov tsos mob ntawm cov ntshav qab zib, nws txoj kev rov txhim kho yog tau. Thaum muaj mob ntshav qab zib ntau lossis ntev heev tom qab qhov kev txhaj tshuaj glucagon los yog dextrose, nws raug pom zoo tias qhov kev ua ntshav yuav ua nrog cov tshuaj tsis muaj zog ntau dhau los txhawm rau txhawm rau tiv thaiv qhov rov txhim kho ntawm hypoglycemia. Hauv cov menyuam yaus, nws yog ib qho tsim nyog yuav tsum ua tib zoo saib xyuas qhov kev mloog ntawm cov piam thaj hauv cov ntshav, nyob rau hauv kev sib txuas nrog kev loj hlob tau ntawm kev muaj ntshav ntau dhau.
Qee qhov xwm txheej, nws raug nquahu kom cov neeg mob mus pw hauv tsev kho mob ntau dua kom tau txais kev saib xyuas lawv tus mob kom zoo thiab saib xyuas cov kev kho mob.

Cov sijhawm so:

Kev daws rau kev txhaj tshuaj 100 IU / ml.
5 ml ntawm cov tshuaj hauv lub raj mis pob tshab thiab tsis muaj kob (hom I). Lub raj mis corked, nyem nrog lub hau txhuas thiab them nrog lub hau taub hau yas. 5 vials nrog cov lus qhia rau kev siv rau hauv lub thawv ntawv thawv. 3 ml ntawm cov tshuaj hauv daim cartridge ntawm cov iav tsis muaj tseeb thiab tsis muaj kob (hom I). Daim cartridge yog corked ntawm ib sab nrog cork thiab nyem nrog ib lub hau txhuas, ntawm qhov tod tes - nrog lub plunger. 5 daim cartridges rau qhov hlwv pob ntawm PVC zaj duab xis thiab txhuas ntawv ci. 1 blister sawb ntim ua ke nrog cov lus qhia siv rau hauv thawv ntawv thawv.
3 ml ntawm cov tshuaj hauv daim cartridge ntawm cov iav tsis muaj tseeb thiab tsis muaj kob (hom I). Daim cartridge yog corked ntawm ib sab nrog cork thiab nyem nrog ib lub hau txhuas, ntawm qhov tod tes - nrog lub plunger. Daim cartridge tau nruab rau hauv SoloStar ® tus cwj mem kua siv pov tseg. Ntawm 5 SoloStar ® syringe cwjmem ua ke nrog daim ntawv thov kev qhia hauv cov thawv ntawv cardboard.

Chaw tsim tshuaj paus - Sanofi-Aventis (Fabkis), Sanofi

Npe: Insuman® Rapid GT, Insuman® Ceev GT

Muaj pes tsawg leeg: 1 ml ntawm cov tshuaj nruab nrab rau kev txhaj tshuaj muaj 100 IU ntawm tib neeg cov tshuaj insulin.
Cov kev zam: m-cresol, sodium dihydrogen phosphate dihydrate, glycerol, sodium hydroxide, hydrochloric acid, dej rau kev txhaj tshuaj.

Pharmacological kev txiav txim: Insuman Rapid GT muaj cov tshuaj insulin, zoo ib yam hauv cov qauv rau tib neeg cov tshuaj insulin thiab tau los ntawm kev tsim kho caj ces. Cov suab thaj txo qis tshwm sim sai, nyob rau hauv 30 feeb, thiab nce mus txog qhov siab kawg nkaus hauv 1-4 teev tom qab kev saib xyuas ntawm cov tshuaj. Cov nyhuv ntev li 7-9 teev. Insuman Rapid GT tuaj yeem sib xyaw nrog txhua tus tib neeg insulins tsim los ntawm Hoechst Marion Roussel, tsuas yog muaj kev zam rau cov insulins uas tau npaj rau kev tswj hwm lub twj tso kua mis.

Kev taw qhia rau kev siv: Mob ntshav qab zib-insulin raws mellitus. Insuman Rapid GT yog qhia rau kev kho mob ntshav qab zib tsis mob plab thiab ketoacidosis, nrog rau kev ua tiav cov nyiaj metabolic hauv cov neeg mob ntshav qab zib mellitus nyob rau hauv kev npaj ua ntej,, thaj tsam -, thiab tom qab lub sijhawm ntev.

Txoj kev siv: Insuman Rapid GT feem ntau yog tswj xyuas kom tob subcutaneously 15-20 feeb ua ntej noj mov. Intramuscular thawj coj ntawm cov tshuaj yog tso cai. Qhov chaw txhaj tshuaj yuav tsum tau hloov txhua zaus.Insuman Rapid GT tuaj yeem muab tshuaj rau hauv kev kho mob ntawm hyperglycemic coma thiab ketoacidosis, ntxiv rau ua tiav cov nyiaj metabolic them ua ntej, rau siab- thiab tom qab lub sijhawm nyob hauv cov neeg mob ntshav qab zib mellitus. Insuman Rapid GT tsis yog siv rau hauv ntau hom tshuaj insulin (suav nrog cov uas siv cog), qhov twg ib qho tshuaj pleev silicone.

Phiv los sis: Qee zaum atrophy lossis hypertrophy ntawm daim ntaub adipose tuaj yeem tshwm sim ntawm qhov chaw txhaj tshuaj, uas tuaj yeem zam tau los ntawm qhov hloov tas mus li qhov chaw txhaj tshuaj.

Muaj qee zaus, me liab yuav tshwm sim ntawm qhov chaw txhaj tshuaj, ploj nrog kev kho txuas ntxiv. Yog tias qhov mob erythema tseem ceeb tau tsim, nrog nws khaus thiab o, thiab nws kis tau nrawm dhau ntawm qhov chaw txhaj tshuaj, nrog rau lwm qhov tsis zoo cuam tshuam rau cov tshuaj ntawm cov tshuaj (insulin, m-cresol), nws yog qhov yuav tsum tau hais qhia rau tus kws kho mob, xws li qee kis cov kev coj ua zoo li no tuaj yeem tsim kev hem thawj rau tus neeg mob lub neej.

Kev tsis haum ntshav siab yog qhov tsawg. Lawv tuaj yeem ua ke nrog kev txhim kho ntawm mob hlwb, mob ntsws, mob ntshav ntws poob thiab tsis tshua nco qab ua kom poob siab. Kev tsis haum lub siab xav tau kev hloov kho tam sim no hauv kev kho mob txuas ntxiv nrog kev siv tshuaj insulin thiab kev saws los ntawm kev ntsuas thaum tsim nyog.

Tej zaum qhov tsim cov tshuaj tiv thaiv rau cov tshuaj insulin, uas tej zaum yuav xav tau kev kho tshuaj ntawm cov tshuaj insulin. Nws tseem muaj peev xwm tso sodium rov qab los ntawm qhov o ntawm cov ntaub so ntswg, tshwj xeeb tshaj yog tom qab kev kawm kho mob ntxiv nrog cov tshuaj insulin.

Cov Tshuaj Tiv Thaiv: Kev rov tiv thaiv kab mob tsis haum rau cov tshuaj insulin lossis rau ib qho twg ntawm cov tshuaj, tshwj tsis yog qee qhov kev kho tshuaj insulin tseem ceeb heev. Hauv cov xwm txheej zoo li no, kev siv Insuman Rapid GT tsuas yog ua tau nrog kev saib xyuas kev kho mob kom zoo thiab, yog tias tsim nyog, muaj kev sib xyaw nrog kev siv tshuaj tiv thaiv kev ua xua.

Kev sib txuam tshuaj: Kev qaug zog ntawm qhov kev ua ntawm cov insulin tuaj yeem raug soj ntsuam nrog kev tswj hwm tib lub sijhawm ntawm insulin thiab corticotropin, corticosteroids, diazoxide, heparin, isoniazid, barbiturates, nicotinic acid, phenolphthalein, phenothiazine derivatives, phenytoin, diuretics, danazole, doxazosin, glucrogen thiab estrogen. homons. Hauv cov neeg mob ib txhij tau txais insulin thiab clonidine, reserpine lossis lithium ntsev, ob qho tib si qaug zog thiab muaj zog ntawm kev ua ntawm insulin tuaj yeem pom. Pentamidine yuav ua rau lub qog ntshav qab zib ua raws li los ntawm hyperglycemia. Haus cawv ntau yuav ua rau lub ntsej muag ntshav qab zib lossis txo qis cov ntshav qab zib kom tsawg mus rau hauv theem txaus ntshai. Cawv kev tso dej caw hauv cov neeg mob tau txais cov tshuaj insulin txo. Tso cai rau haus dej haus cawv ntau npaum yuav tsum yog txiav txim los ntawm koj tus kws kho mob. Kev haus cawv ntev ntev, nrog rau mob ntev mus ntev yog siv cov tshuaj tso quav, yuav cuam tshuam rau glycemia. Beta-blockers ua rau muaj kev pheej hmoo ntawm hypoglycemia thiab, nrog rau lwm cov tshuaj sympatholytic (clonidine, guanethidine, reserpine) tuaj yeem ua kom tsis muaj zog lossis tseem npog qhov pom ntawm cov ntshav qog ntshav qab zib.

Cev xeeb tub thiab lactation: Kev kho mob nrog Insuman Rapid GT yuav tsum txuas ntxiv thaum cev xeeb tub. Thaum cev xeeb tub, tshwj xeeb tshaj yog tom qab thawj peb hlis, yuav tsum ua kom muaj cov tshuaj insulin ntau ntxiv. Txawm li cas los xij, tam sim ntawd tom qab yug los, xav tau cov tshuaj insulin feem ntau poob qis, uas ua rau muaj kev pheej hmoo loj ntxiv ntawm lub qog ntshav qab zib. Thaum lub sijhawm pub niam mis, tsis muaj kev txwv dab tsi rau kev kho mob insulin. Txawm li cas los xij, yuav tsum tau txhaj tshuaj thiab kev noj zaub mov kom haum.

Cia rau cov neeg mob: Khaws ntawm qhov kub ntawm + 2 ° C txog + 8 ° C. Tsis txhob cia kom txias, tsis txhob sib chwv lub hwj nrog lub phab ntsa ntawm lub tub yees txias lossis khoom txias cia.

Yeem: Nrog kev ceev faj, qhov ntau dua kev noj tshuaj yog xaiv rau cov neeg mob uas muaj cov kab mob cerebrovascular ua ntej lawm raws li hom ischemic thiab nrog cov ntawv hnyav ntawm ischemic plawv. Qhov xav tau rau insulin tuaj yeem hloov pauv thaum koj hloov mus rau lwm hom insulin (thaum hloov insulin ntawm tsiaj keeb kwm nrog Insuman Rapid, cov koob tshuaj feem ntau raug txo qis), nrog kev hloov pauv ntawm kev noj zaub mov, raws plab, ntuav, qhov hloov pauv ib txwm los ntawm kev ua haujlwm ntawm lub cev, kab mob ntawm lub raum, mob siab, lub qog pituitary, cov thyroid caj pas, hloov chaw txhaj tshuaj. Tus neeg mob yuav tsum tau qhia paub txog cov tsos mob ntawm lub xeev hypoglycemic, txog thawj cov tsos mob ntawm tus mob ntshav qab zib tsis nco qab thiab txog qhov yuav tsum tau qhia rau tus kws kho mob txog txhua yam kev hloov pauv hauv nws tus mob.

Novorapid yog cov khoom lag luam hloov pauv, qhov kev nqus ntawm qhov tsis xav tau cov khoom noj ntxiv, thiab kev txhaj tshuaj tuaj yeem ua tau ob qho tib si tom qab noj mov thiab ua ntej noj mov. Tus txheej txheem kho tau ntev li 4 teev. Insuman Rapid yog ib qho piv txwv ntawm tib neeg cov tshuaj hormones, kev noj uas cuam tshuam nrog kev noj zaub mov los yog khoom noj txom ncauj, nrog rau kev qhia yuav tsum tau txhaj tshuaj subcutaneous 40 feeb ua ntej noj mov. Lub sijhawm siv ntawm cov nyhuv yog li 6 teev. Ob txoj kev daws no tsis luv, thiab kws kho mob feem ntau nyiam hloov chaw ib tus tsis muaj teeb meem rau tus neeg mob lub noj qab haus huv.

Ntshav qab zib tshuaj saib ib muag

Novorapid belongs rau cov tsim kho tshuaj tshiab kawg. Cov tshuaj yuav pab ua kom tiav rau qhov tsis muaj tshuaj txaus rau tib neeg, muaj ntau tus yam ntxwv thiab zoo dua lwm cov tshuaj ntawm tib pab pawg:

• Kev zom zom ceev ceev.
• Kev poob sai hauv cov piam thaj.
• Tsis muaj kev vam khom rau cov khoom noj txom ncauj tas mus li.
• Ultrashort raug.
• Cov ntaub ntawv tso tawm yooj yim.

Novorapid tiv thaiv endocrine pathology muaj nyob hauv daim iav hloov chaw (Penfill) thiab hauv cov qauv ntawm cov npiv npauj (FlexPen). Cov tshuaj lom neeg rau hauv ob hom tso tawm yog zoo tib yam. Cov tshuaj tau ruaj ntseg ntim, thiab qhov tshuaj hormones nws tus kheej tau yooj yim los siv rau hauv ib hom tshuaj pharmacological.

Cheebtsam thiab muaj pes tsawg leeg

Cov ntsiab lus tseem ceeb ntawm Novorapid yog xam raws li tag nrho cov ntsiab lus ntawm cov khoom siv rau ib 1 ml ntawm cov tshuaj. Cov tshuaj phiv yog cov tshuaj insulin aspar 100 units (kwv yees li 3.5 mg). Ntawm ntu ntu, muaj:

• Glycerol (txog 16 mg).
• Metacresol (li ntawm 1.72 mg).
• Zinc chloride (txog 19.7 mcg).
• Sodium chloride (nce txog 0.57 mg).
• Sodium hydroxide (txog 2.2 mg).
• Hydrochloric acid (txog 1.7 mg).
• Phenol (txog li 1.5 mg).
• Cov dej lim (1 ml).

Cov twj yog qhov tseeb daws tsis muaj xim hais, nyob hauv av.

Sib haum

Novorapid muaj lub suab hypoglycemic zoo vim yog lub ntsiab tshuaj insulin aspart. Qhov insulin zoo li no yog kev pev ntawm qhov tsis ntev ntawm tib neeg lub cev. Cov khoom siv tau tau los ntawm ntau cov txheej txheem thev naus laus zis nyob rau theem ntawm cov DNA tso tseg. Cov tshuaj Insulin Novorapid nkag mus rau hauv kev sib raug zoo lom neeg nrog cov cell receptors, tsim ib qho kev nyuaj ntawm cov leeg kawg.

Cov tshuaj no tuaj yeem siv rau txhua hom ntshav qab zib hauv cov neeg laus thiab menyuam yaus txij li 2 xyoos!

Tawm tsam keeb kwm yav dhau los ntawm qhov txo qis hauv qhov glycemic Performance index, ib qho kev nce ntxiv ntawm kev coj ua thaum kawg, kev ua haujlwm ntawm lipogenesis thiab glycogenogenesis cov txheej txheem, nrog rau kev nce ntxiv ntawm kev nqus ntawm ntau cov nqaij mos. Nyob rau tib lub sijhawm, kev ua haujlwm ntawm cov piam thaj los ntawm daim siab ua haujlwm raug txo qis. Novorapid zoo dua nqus los ntawm lub cev, muaj cov nyhuv kho tau sai dua li cov tshuaj insulin. Thawj 3-4 teev tom qab noj mov, insulin aspart txo cov ntshav muaj piam thaj ntau ntau dua li tib neeg cov insulin, tab sis Novorapid cov nyhuv luv dua nrog kev txhaj tshuaj subcutaneous dua li los ntawm insulin ntuj tsim los ntawm tib neeg lub cev.

Kev taw qhia thiab contraindications

Cov tshuaj muaj qhov cim tseem ceeb - ntshav qab zib ntawm ib yam rau cov menyuam yaus txij li 2 xyoo, cov hluas thiab cov neeg laus.

Kev siv cov tshuaj tiv thaiv hypoglycemic yuav tsum tau kho nrog ceev faj vim muaj kev phiv. Novorapid tsis pom zoo rau kev siv nrog tus kheej tsis kam ua rau cov khoom siv, kev tsis haum tshuaj rau ib qho twg ntawm cov tshuaj Novorapid. Cov kev kho mob hauv cov menyuam yaus hnub nyoog qis dua 2 xyoos tsis paub vim tsis muaj kev tshawb fawb hauv cov neeg mob ntawm cov pab pawg hnub nyoog no.

Cov lus qhia tshwj xeeb

Ib qho ntawm cov teeb meem uas nquag muaj nrog cov kev tswj hwm zoo hauv lub cev yog qhov ntshav qab zib tsawg. Feem ntau, qhov tshwm sim yog los ntawm kev siv lub tshuaj tsis yog, ua txhaum txoj cai ntawm cov thawj coj. Novorapid muaj lub sijhawm ua haujlwm luv, tab sis muaj qhov pib sai. Qhov no yuav txo qhov kev pheej hmoo ntawm nocturnal hypoglycemia. Qhov ntau npaum li cas yog xaiv tau nruj me ntsis ntawm tus kheej, uas yog vim qhov kev tshawb nrhiav keeb kwm ntawm tus neeg mob, qhov muaj feem yuav ua rau exacerbations ntawm concomitant kab mob, hnub nyoog thiab xwm ntawm cov chav kawm mob ntshav qab zib. Nrog rau cov xwm txheej muaj keeb kwm mob hnyav, nws raug pom zoo kom saib xyuas cov lej glycemic ntau ntxiv hauv txhua pawg ntawm cov neeg mob. Novorapid tuaj yeem ua rau muaj kev tsis haum tshuaj nyob rau hauv cov menyuam yaus.

Tus txheej txheem ntawm kev ua ntawm cov tshuaj

Tau los ntawm kev tshuaj ntsuam genetic engineering, insulin Insuman Rapid GT zoo ib yam li cov tshuaj hormones uas ua los ntawm tib neeg pancreatic beta hlwb. Cov tshuaj tau tawm hauv cov tshuaj uas tsis muaj xim, uas yog txhaj.

Cov tshuaj nquag siv ntawm cov tshuaj yog tib neeg cov tshuaj insulin. Ntxiv rau nws, qhov kev npaj muaj ib qho me me ntawm lwm qhov: glycerol (85%), sodium hydroxide, m-cresol, hydrochloric acid, sodium dihydrogen phosphate dihydrate thiab dej distilled.

Ib nrab ib teev tom qab cov tshuaj hormones nkag mus rau hauv tib neeg lub cev, nws pib ua. Qhov siab tshaj plaws ua rau kev kho mob tuaj dhau 1-3 teev tom qab txhaj tshuaj thiab kav rau 8 teev. Thaum lub sijhawm nws ua, insulin muaj cov teebmeem hauv qab no ntawm lub cev:

• txo hauv cov ntshav qabzib concentration,
• txhim kho cov txiaj ntsig anabolic, uas yog, hloov kho thiab tsim kho cov hlwb tshiab,
• inhibition of catabolic kev ua - kev zom zaub mov metabolic,
• nce qabzib thauj mus rau hauv lub hlwb, tsim cov glycogen hauv lub siab thiab cov leeg,
• kev siv cov piam thaj feem xaus cov khoom lag luam - pyruvates,
• kev tsuj ntawm glycogenolysis, glyconeogenesis thiab lipolysis,
• nce lipogenesis hauv daim ntaub so ntswg thiab cov nplooj siab,
• txhim kho cov poov tshuaj kom tsawg dua hauv qib qis.

Hauv kev xyaum kho mob, Insuman Rapid yog sib xyaw nrog lwm cov tib neeg insulins, uas yog tsim los ntawm Hoechst Marion Roussel, tshwj tsis yog cov tshuaj hormones uas siv rau hauv cov nqus dej.

Analogs thiab generics

Cov tshuaj hormone Novorapid tuaj yeem hloov nrog lwm cov tshuaj ntawm tib pab pawg. Cov duab qhia yuav raug xaiv tsuas yog tom qab kuaj mob meej. Cov analogues loj muaj xws li Humalog, Actrapid, Protafan, Gensulin N, Apidra, Novomiks thiab lwm tus. Tus nqi ntawm Novorapid hormone hauv cheeb tsam sib txawv nws txawv ntawm 1800 txog 2200 rau ib pob.

Novomix tuaj yeem dhau los ua qhov hloov pauv rau Novorapid.

Hauj lwm lawm

• Cov tshuaj hormones insulin 3,571 mg (100 IU 100% tib neeg soluble hormone).
• Metacresol (txog 2.7 mg).
• Glycerol (kwv yees li 84% = 18.824 mg).
• Dej rau kev txhaj tshuaj.
• Sodium dihydrogen phosphate dihydrate (li ntawm 2.1 mg).

Kev ua neeg insuman sai gt sawv cev los ntawm cov kua tsis muaj kob uas tsis muaj dab tsi. Nws yog rau cov pab pawg ntawm cov neeg sawv cev luv luv hypoglycemic. Insuman tsis tsim cov kev ua kom yuag txawm nyob rau lub sijhawm ntev cia.

Cov chaw muag tshuaj

Insuman Ceev Heev GT muaj cov tshuaj hormones uas yog cov yam ntxwv zoo ib yam li tib neeg cov keeb. Cov tshuaj tau los ntawm kev tsim hluav taws xob. Cov kev ua haujlwm tseem ceeb ntawm kev ua ntawm Insuman suav nrog:

• Txo cov ntshav muaj ntshav qabzib.
• Kev txo qis ntawm cov txheej txheem catabolic.
• Ntxiv dag zog rau qhov hloov chaw ntawm cov piam thaj tob hauv cov hlwb.
• Txhim kho lipogenesis nyob rau hauv nplooj siab qauv.
• Ntxiv dag zog rau kev nkag mus ntawm cov poov tshuaj.
• Kev ua kom muaj protein thiab amino ua kom sib txuas.

Insuman Ceev Heev GT Nws muaj kev pib sai ntawm kev txiav txim, tab sis muaj lub sijhawm luv luv. Qhov ua rau lub ntsej muag hypoglycemic tau tiav twb ib nrab ntawm ib teev tom qab kev coj ua tom qab ntawm cov tshuaj Cov nyhuv kav ntev txog 9 teev.

Cov xwm txheej hauv qab no yuav tsum tau muab ntaus nqi rau cov cim tseem ceeb:

• Ntshav qab zib kab mob (hom insulin-raws hom).
• Coma nyob rau keeb kwm ntawm ntshav qab zib.
• Kev nce qib ketoacidosis.
• Qhov xav tau ntawm kev them nyiaj metabolic (piv txwv, ua ntej lossis tom qab phais mob).

Lub ntsiab contraindications suav nrog hypoglycemia lossis kev pheej hmoo siab ntawm kev txo qis hauv cov ntshav qab zib, kev fab tshuaj rau ib qho twg hauv cov tshuaj tsis haum, tshuaj tiv thaiv ntau dhau.

Thaum muab tshuaj rau ib tug noj tshuaj Insuman Ceev Heev GT tus kws kho mob yuav siv sij hawm mus rau hauv tus account ntau lub ntsiab lus: hnub nyoog, keeb kwm kho mob, feem ntau cov mob ntshav qab zib, muaj cov kab mob mus ntev ntawm cov nruab nrog cev thiab muaj kab mob sib cuam tshuam. Qee zaum siv tshuaj kho mob ntshav qab zib txwv tsis pub tsav tsheb lossis ua haujlwm hauv cov chaw muaj kev phom sij.

Tus nqi nruab nrab ntawm cov tshuaj hauv thaj tsam sib txawv nws txawv ntawm 700 txog 1300 rubles rau ib pob.

Nqi Nyob ntawm ntau yam sib txawv.

Ob qhov tshuaj yog cov tshuaj tiv thaiv hypoglycemic luv luv. Ib qho kev hloov pauv ntawm cov tshuaj tiv thaiv ntshav qab zib yog nqa tawm tsuas yog tom qab sab laj tus kws tshaj lij. Insuman Ceev Heev GT tso cai rau koj tswj lub neej li qub ntawm tus neeg mob nyob rau hauv ntau yam mob ntawm cov ntshav qab zib. Novorapid muaj cov yam ntxwv zoo ib yam Insuman Ceev Heev GT, tab sis yuav luag tag ua rau tib neeg cov insulin.

Insuman Ceev Heev GT muaj cov tshuaj insulin zoo tib yam hauv cov qauv rau tib neeg cov insulin thiab tau los ntawm kev tsim kho caj ces siv K12 limtiam E. Coli.

Cov Ntawv Pov Thawj Tsis Txaus Ntseeg Insuman Sai Sai GT

• ntshav qab zib,
• muaj tshuaj tiv thaiv qhov tsis haum rau insulin lossis rau ib qho twg ntawm cov tshuaj tiv thaiv.

Nrog saib xyuas cov tshuaj yuav tsum tau siv thaum muaj teeb meem lub raum (qhov xav tau ntawm insulin vim tias qhov ua kom cov insulin tsawg dua tuaj yeem ua tau), hauv cov neeg mob laus (maj mam ua haujlwm hauv lub raum ua haujlwm tuaj yeem ua rau muaj kev cuam tshuam mus tas li ntawm kev xav tau cov tshuaj insulin), hauv cov neeg mob uas muaj lub siab tsis ua hauj lwm (xav tau cov tshuaj insulin tuaj yeem txo vim yog rau ib qho kev txo qis hauv kev muaj peev xwm gluconeogenesis thiab kev txo qis hauv cov tshuaj insulin metabolism), hauv cov neeg mob uas mob hnyav ntawm lub plawv thiab cov hlab ntsha hauv lub cev (hypoglycemic episodes yuav ntawm cov ntsiab lus tseem ceeb hauv tsev kho mob, vim tias muaj kev pheej hmoo ntawm lub plawv lossis mob hlwb ntau dua ntawm cov ntshav qab zib (hypoglycemia), hauv cov neeg mob uas muaj kev mob hlwb (tshwj xeeb tshaj yog cov uas tsis tau txais kev kho mob nrog photocoagulation (kho laser), vim tias lawv muaj kev pheej hmoo ntawm amaurosis nrog hypoglycemia tiav - ua tiav qhov muag tsis pom ), hauv cov neeg mob uas muaj cov kabmob sib kis (qhov xav tau ntawm insulin feem ntau nce).

Cov tshuaj yog xaiv ntawm tus kheej, nyob rau hauv kev saib xyuas ntawm kws kho mob. Nkag mus sau txhua txhua 4-6 teev

Kev siv tshuaj hypoglycemic, luv luv ua yeeb yam insulin. Insuman Rapid muaj cov insulin, zoo ib yam hauv cov qauv rau tib neeg insulin thiab tau los ntawm kev tsim kho caj ces siv K12 limtiam E. coli.

Cov tshuaj insulin txo cov concentration ntawm cov piam thaj hauv cov ntshav, txhawb cov teebmeem anabolic thiab txo cov teebmeem catabolic. Nws nce cov piam thaj hauv kev thauj mus rau hauv cov hlwb thiab kev tsim cov glycogen hauv cov leeg thiab daim siab, txhim kho kev siv pyruvate, thiab inhibits glycogenolysis thiab glyconeogenesis. Cov tshuaj insulin nce lipogenesis nyob rau hauv daim siab thiab adipose ntaub so ntswg thiab inhibits lipolysis. Txhawb nqa qhov khiav ntawm cov amino acids rau hauv cov hlwb thiab kev sib sau ntawm cov protein, ua kom cov pa roj ntau ntau ntxiv rau hauv lub cell.

Insuman Rapid yog insulin nrog kev pib sai thiab lub sijhawm luv luv ntawm kev ua. Tom qab cov thawj coj sc, cov nyhuv hypoglycemic tshwm sim li ntawm 30 feeb, nce mus txog qhov siab kawg hauv 1-4 teev, tseem mob siab rau 7-9 teev.

Kev Phiv Phom Kab Mob Insuman Rapid GT

Los ntawm cov kab mob plawv: zaus tsis paub - txo ntshav siab.

Los ntawm sab ntawm cov metabolism thiab khoom noj khoom haus: feem ntau - edema, tsis paub ntau zaus - sodium tuav tseg. Cov teebmeem zoo sib xws yog muaj peev xwm ua tau nrog kev txhim kho ntawm kev tswj kab mob metabolic yav dhau los tsis txaus vim kev siv tshuaj ntau ntxiv kev siv tshuaj insulin.

Los ntawm sab ntawm cov khoom ntawm lub zeem muag: qhov zaus tsis paub txog - kev cuam tshuam txog kev hloov pauv tsis tu ncua (vim kev hloov pauv hloov chaw nyob ib ntus ntawm lub qhov muag ntawm lub qhov muag thiab lawv qhov ntsuas qhov ntsuas tsis tau), kev cuam tshuam ib ntus hauv cov mob ntshav qab zib retinopathy (vim yog muaj kev kho mob insulin ntau dua nrog kev txhim kho glycemic tswj), hloov chaw ntawm amaurosis (hauv cov neeg mob uas muaj kev tiv thaiv kev mob hlwb, tshwj xeeb tshaj yog tias lawv tsis tau txais kev kho mob nrog photocoagulation (kho laser).

Ntawm ib feem ntawm daim tawv nqaij thiab cov nqaij mos subcutaneous: qhov zaus tsis paub meej - kev txhim kho ntawm lipodystrophy ntawm qhov chaw txhaj tshuaj thiab qhov qeeb hauv kev nqus hauv zos ntawm insulin. Hloov cov chaw txhaj tshuaj tsis tu ncua hauv thaj chaw tswj kev pom zoo tuaj yeem pab txo lossis tso tseg cov kev cuam tshuam no.

Kev cuam tshuam dav dav thiab cuam tshuam ntawm qhov chaw txhaj tshuaj: qhov zaus tsis paub meej - liab, mob, khaus, urticaria, o lossis mob tshwm sim ntawm qhov chaw txhaj tshuaj. Cov kev tsis haum siab hais txog cov tshuaj insulin ntawm qhov chaw txhaj tshuaj feem ntau ploj tom qab ob peb hnub lossis ntau lub lis piam.

Cov tsos mob kev noj tshuaj insulin ntau dhau, piv txwv li, kev qhia ntawm cov insulin ntau heev piv nrog kev noj zaub mov lossis lub zog, tuaj yeem ua rau lub cev ntshav qis thiab qee zaum muaj ntshav nce ntshav tsawg.

Kev Kho Mob: kev mob ntshav qog ua si (hypoglycemia) me me (tus neeg mob nco qab) tuaj yeem nres los ntawm kev noj cov tshuaj carbohydrates hauv. Nws yog qhov yuav tsum tau kho lub koob tshuaj insulin, kev noj zaub mov thiab ua si lub cev. Yuav muaj ntau qhov teeb meem mob ntshav qab zib ntau ntau nrog kev tsis nco qab, ua kom mob hlwb lossis mob hlwb puas tuaj yeem nres nrog a / m lossis s / c tswj hwm ntawm glucagon lossis i / v nrog cov tshuaj dextrose. Hauv cov menyuam yaus, qhov ntau npaum li cas ntawm dextrose raug tswj hwm tau tsim raws li qhov ntsuas lub cev ntawm tus menyuam. Tom qab nce lub siab ntawm cov piam thaj nyob rau hauv cov ntshav, txhawb kev noj haus ntawm cov carbohydrates thiab kev soj ntsuam yuav tsum tau ua, raws li tom qab pom tseeb hauv kev kho mob kom tshem tawm cov tsos mob ntawm kev mob ntshav qab zib, nws txoj kev rov txhim kho yog tau. Yog tias muaj teeb meem mob ntshav qab zib ntau lossis ntev heev tom qab qhov kev txhaj tshuaj glucagon los yog dextrose, nws pom zoo tias qhov kev daws teeb meem dextrose tsawg dua yuav ua rau muaj kev tiv thaiv kom rov qab txhim kho hypoglycemia. Hauv cov menyuam yaus, nws yog ib qho tsim nyog yuav tsum ua tib zoo saib xyuas qhov kev mloog ntawm cov piam thaj hauv cov ntshav, nyob rau hauv kev sib txuas nrog kev loj hlob tau ntawm kev muaj ntshav ntau dhau. Qee qhov xwm txheej, nws raug nquahu kom tus neeg mob yuav tsum tau mus pw hauv tsev kho mob kom tau txais kev saib xyuas lawv tus mob kom zoo thiab saib xyuas kev kho kom zoo.

Siv cov tshuaj tsis haum nrog lub qhov ncauj hypoglycemic, ACE inhibitors, disopyramide, fibrates, fluoxetine, MAO inhibitors, pentoxifylline, propoxyphene, salicylates, amphetamine, anabolic steroids thiab txiv neej cov tshuaj hormones, cybenzoline, phenophosphamine, phenophosphamine thiab phenophosphamine nws cov analogues, sulfonamides, tetracyclines, tritokvalin lossis trophosphamide tuaj yeem txhim kho hypoglycemic nyhuv ntawm insulin thiab nce draspolozhennost hypoglycemia.

Lub simultaneous siv corticotropin, corticosteroids, danazol, diazoxide, diuretics, glucagon, Isoniazid, oestrogens thiab gestagens (e.g., tam sim no nyob rau hauv PDA), phenothiazine derivatives, kev loj hlob lawm, sympathomimetic tshuaj (e.g., epinephrine, salbutamol, terbutaline), cov thyroid hormones, barbiturates, nicotinic acid, phenolphthalein, phenytoin derivatives, doxazosin tuaj yeem txo cov nyhuv hypoglycemic ntawm insulin.

Beta-blockers, clonidine, lithium ntsev tuaj yeem yog potentiate lossis ua kom cov ntshav tsis muaj zog ntawm insulin.

Ethanol tuaj yeem ua rau muaj zog lossis ua kom cov nyhuv tsis muaj zog ntawm insulin. Kev noj tshuaj Ethanol tuaj yeem ua rau cov ntshav qabzib lossis txo qis cov ntshav qabzib dhau mus rau qib txaus ntshai. Kev noj tshuaj Ethanol hauv cov neeg mob uas tau txais insulin yog txo. Tus kws kho mob yuav tsum txiav txim siab noj ntau npaum li cas ntawm kev noj tshuaj ethanol.

Nrog rau kev siv ua ke nrog pentamidine, kev txhim kho hypoglycemia yog ua tau, uas muaj peev xwm qee zaum tig mus rau hauv hyperglycemia.

Nrog rau kev siv tib lub sijhawm nrog cov neeg mob sympatholytic, xws li beta-blockers, clonidine, guanethidine thiab reserpine, qhov ua kom tsis muaj zog lossis ua tiav ntawm cov tsos mob ntawm tus mob reflex (nyob rau hauv teb rau hypoglycemia) kev ua kom zoo ntawm cov leeg hlwb muaj peev xwm ua tau.

Cov tshuaj yuav tsum muab cia rau hauv qhov chaw tsaus, tawm ntawm cov menyuam yaus ntawm qhov kub ntawm 2 ° C txog 8 ° C. Txee lub neej: 2 xyoos.

Muaj daim ntawv yuav tshuaj

Ib tus neeg txoj kev xav rau lub neej noj qab nyob zoo, txwv kev siv cov khoom lag luam ua phem, ua si lub cev thiab tsis muaj lub cev tsis zoo yog qhov tseem ceeb rau kev tswj hwm tib neeg kev noj qab haus huv nyob rau hauv Feem ntau. Txawm li cas los xij, qee zaum, tawm tsam ib qho laj thawj, ib tus neeg uas kho nws txoj kev noj qab haus huv thiab ua tib zoo, tau ntsib nrog cov teeb meem ntawm cov metabolism hauv lub cev. Yuav ua li cas qhov no tshwm sim yog tias ib tus neeg tsis haus cawv, tsis ua kom noj ntau dhau hauv zaub mov, zam kev ntxhov siab thiab ua lub cev? Yog vim li cas, hmoov tsis, lus dag hauv cov kab mob hereditary predisposition, uas yog qhov txiav txim siab hauv qhov no, pov thawj ntawm uas tuaj yeem yog tus kab mob ntawm hom 1 ntshav qab zib mellitus. Lub peculiarity ntawm no mob yog dab tsi thiab dab tsi yog qhov mechanism ntawm nws txoj kev loj hlob?

Mob ntshav qab zib yog dab tsi?

Hom 1 mob ntshav qab zib mellitus yog ib qho mob uas tshwm sim vim kev tuag ntawm qee cov cell uas tsim cov tshuaj insulin nyob rau hauv lub txiav. Kev tshem tawm ntawm cov hlwb thiab txuas ntxiv cov tshuaj insulin ua rau muaj kev cuam tshuam tsis zoo ntawm cov metabolism hauv kev ua haujlwm thiab hyperglycemia.

Hauv qhov no, tus neeg mob yuav hnov ​​cov tsos mob li nram no:

Tus kab mob no, tsis yog kuaj tau raws sijhawm, tuaj yeem ua rau tus neeg tsis tuaj yeem hloov pauv hauv lub raum, mob plawv, txiav tes taw thiab tuag taus. Vim li ntawd thiaj li tseem ceeb heev uas yuav tau txeeb tus kab mob thaum nws tsuas tshwm sim kom pib kho tau raws sijhawm.

Vim li cas cov tshuaj insulin thiaj li tseem ceeb rau lub cev?

Txij li thaum hom mob no zoo nkaus li tiv thaiv keeb kwm ntawm insulin tsis txaus, tom qab ntawd kev kho mob yuav tsum cuam tshuam nrog kev rov ua qhov tsis txaus ntawm qhov hormone no rau lub cev. Txawm li cas los xij, rau cov pib me me nws yog qhov tseem ceeb kom nkag siab qhov nws lub luag haujlwm hauv cov txheej txheem hauv kev zom zaub mov.

Cov haujlwm uas nws daws yog muaj raws li hauv qab no:

• Kev cai ntawm kev tawg ntawm cov piam thaj, uas yog lub hauv paus tseem ceeb ntawm kev noj haus rau cov leeg nqaij thiab cov hlwb paj hlwb.
• Ua ke nrog kev nkag mus ntawm cov suab thaj hauv cov phab ntsa ntawm cov hlwb ntawm cov leeg.
• Kho qhov siv ntawm qhov tsim ntawm cov rog thiab cov protein, nyob ntawm qhov xav tau ntawm lub cev.

Txij li thaum cov tshuaj insulin tsuas yog tib qho hormone uas muaj qhov ntau thiab ntau cov haujlwm, nws yog qhov tseem ceeb rau lub cev tib neeg. Yog vim li cas thiaj muaj ntshav qab zib, tus neeg mob tau yuam kom nqa cov tshuaj uas nws muaj nyob ze rau hauv lub cev no.Cov tshuaj no cawm tus neeg mob los ntawm kev txhim kho hauv kev tsis tuaj yeem ntawm lub hauv nruab nrog cev thiab cov hlab ntsha.

Hom mob insulin

Lub ntsiab sib txawv ntawm analogues ntawm tib neeg cov insulin hnub no yog cov yam xws li:

• Cov tshuaj yog dab tsi.
• Lub sijhawm tiv thaiv ntawm cov tshuaj.
• Qhov kev ua kom huv si ntawm cov tshuaj.

Los ntawm cov kev tshwj xeeb ntawm kev tsim khoom, kev npaj tuaj yeem muab faib ua cov nyiaj tau los ntawm nyuj, uas feem ntau ua rau muaj kev phiv thiab ua xua, los ntawm npua thiab tau los ntawm kev tsim caj ces. Xws li cov tshuaj suav nrog, piv txwv li, German Insulin Rapid GT.

Raws li lub sijhawm sib xyaw nrog, cov tshuaj tau muab faib ua hom:

• Cov tshuaj insulin luv luv, uas tau siv sijhawm rau ib hlis twg ntawm ib teev ua ntej noj mov, txhawm rau kom phim qhov kev loj hlob ntawm cov tshuaj hormone hauv tus neeg noj qab haus huv tom qab noj mov. Cov peev nyiaj no suav nrog Insulin Insuman Rapid.
• Lub caij nyoog ntev, uas yuav tsum muaj kev tswj hwm ib zaug lossis ob zaug hauv ib hnub, txhawm rau txhawm rau ua qhov tsis zoo no feem ntau lawm ntawm yam tshuaj no.

Feem ntau, ob hom tshuaj hormones yog muab rau tus neeg mob kom txaus siab qhov xav tau ntawm lub cev txhua hnub. Txawm li cas los xij, rau cov neeg uas tsis tuaj yeem tswj hwm lawv tus mob vim muaj hnub nyoog lossis lub hlwb tsis zoo, suav cov tshuaj kwv yees raws li tau siv. Muaj lub luag haujlwm thiab ua tib zoo saib xyuas kev hloov pauv hauv nws tus mob, ib tug neeg muaj peev xwm suav nws tus kheej qhov koob tshuaj ntawm Insulin Rapid sai.

Nta ntawm kev noj tshuaj

Kev noj tshuaj luv luv tso cai rau tus neeg mob nws tus kheej npaj nws txoj kev noj haus, tsis hais ncaj qha rau kev noj zaub mov kom zoo thiab nyob rau ntawm tus niaj hnub ua. Txhawm rau ua qhov no, nws yog ib qho tseem ceeb kom ntsuas cov khoom noj ntawm carbohydrates thiab theem ntawm cov piam thaj hauv cov ntshav ua ntej noj mov.

Txais tos ntawm Insulin Insuman Rapid GT tuaj yeem txhim kho lub neej kev mob ntawm tus neeg mob, vim nws ua rau nws muaj peev xwm coj mus rau hauv tus kheej lub suab nrov ntawm tus neeg lub neej, nws kev noj haus.

Cov txheej txheem ntawm kev siv tshuaj thiab ntau npaum li cas, nrog rau cov yam ntxwv ntawm kev pub nkag thiab contraindications, yuav tsum tau ua tib zoo kawm raws li cov lus qhia rau Insulin Rapid, thiab tseem tham nrog koj tus kws kho mob. Tsis tas li ntawm qhov tseem ceeb yog tus neeg mob lub peev xwm los kho qhov tseeb ntawm koob tshuaj.

Cov cuab yeej no hais txog cov tshuaj uas siv rau cov neeg mob ntshav qab zib. Cov chaw tsim khoom yog Fabkis lub tuam txhab tshuaj.

Cov yam ntxwv ntawm cov tshuaj yog dab tsi, siv li cas kom raug, nws muaj txiaj ntsig zoo dua lwm cov tshuaj, thiab nws tau qhia rau txhua tus neeg mob? Muaj ntau cov lus nug, tab sis rau txhua ntawm lawv koj tuaj yeem nrhiav lo lus teb hauv kab lus no.

Tus yam ntxwv thiab muaj pes tsawg leeg

Cov tshuaj Insuman sai sai muaj nyob rau hauv daim ntawv ua kua, qhov no yog kev daws teeb meem, nws tau txhaj hauv qab daim tawv. Cov cim tseem ceeb rau kev siv yog kab mob: ntshav qab zib mellitus, ketoacidosis, coma.

Cov tshuaj yeeb dej caw nquag yog tib neeg insulin hauv daim ntawv ntawm 100% tshuaj (3,571 mg).

Cov khoom siv hauv ib puag ncig muaj xws li: m-cresol, sodium dihydrogen phosphate dihydrate, sodium hydroxide, glycerol, hydrochloric acid, dej siv rau kev txhaj tshuaj.

Cov tshuaj tsis muaj xim, nws yog kom pom tseeb.

Cov yam ntxwv ntawm Pharmacological

Cov tshuaj zoo ib yam li tib neeg cov kua dej yog tsim nyob rau hauv txoj kev niaj hnub siv kev tsim hluav taws xob. K 12 hom ntawm E. Coli raug coj los ua cov khoom pib.

Cov chaw muag tshuaj ntawm cov tshuaj muaj raws li nram no:

Insuman Rapid HT yog qhov "insulin ceev" uas muaj peev xwm ua tiav cov nyhuv hypoglycemic nyob rau hauv ib nrab teev tom qab txhaj tshuaj subcutaneous, thiab nyob rau hauv 3-4 teev muaj kev tshaj tawm tag nrho ntawm qhov muaj peev xwm kho tau ntev tshaj plaws, ntev li 9 teev.

Daim ntawv thov, ntau npaum li cas rau ntau pab pawg ntawm cov neeg mob

Nws tsim nyog hais tias qhov muab tshuaj yog txuam nrog ntau yam ntxwv ntawm tus neeg mob nws tus kheej.

Tus kws kho mob hauv ib tus neeg nqa tawm ib qho kev teem sij hawm uas siv cov hauv qab no:

Qhov yuav tsum tau yog tus neeg mob lub peev xwm los kho cov tshuaj insulin, uas suav nrog tsis tsuas yog lub peev xwm los ntsuas cov ntshav qabzib hauv cov zis thiab ntshav, tabsis tseem tuaj yeem siv los txhaj tshuaj.

Raws li kev kho mob zuj zus mus, tus kws kho mob tswj xyuas kev noj haus ntau npaum li cas thiab kho kom haum rau cov khoom noj thiab kho qhov hloov ntawd lossis lwm yam kev hloov pauv ntawm koob tshuaj. Nyob rau hauv ib lo lus, qhov kev lav paub kho tau zoo heev yuav tsum tau ua rau ib tus neeg muaj kev xav ntau thiab mloog nws tus kheej.

Muaj qhov tawm ntawm cov tshuaj, nws yog cim los ntawm qhov nruab nrab ntawm cov tshuaj insulin nyob rau ib phaus ntawm tus neeg mob lub cev qhov hnyav thiab thaj tsam li 0.5 txog 1.0 IU. Hauv qhov no, yuav luag 60% ntawm tsuas tshuaj yog cov neeg siv tshuaj insulin ntev.

Yog tias ua ntej Insuman Rapid HT, ntshav qab zib siv tshuaj yeeb nrog cov tshuaj ua kom muaj zog los ntawm cov tsiaj keeb kwm, ces tus nqi ntawm tib neeg insulin yuav tsum tau pib txo.

Koj yuav tsum tsis txhob hloov ntawm lwm hom tshuaj rau qhov no yam tsis muaj kev paub txog ntawm tus kws kho mob; kev saib xyuas tshwj xeeb yog qhov yuav tsum tau nyob ntawm no, txwv tsis pub muaj cov teeb meem uas tsis paub ua ntej yuav tshwm sim thiab tus mob yuav phem dua. Lub sijhawm hloov pauv no tau hais tawm nyob rau hauv kev hloov pauv hauv cov metabolism hauv cov metabolism hauv ob peb hnub.

Cov lus qhia ntawm cov tshuaj hauv cov lus nug yog nqa tawm tob hauv daim tawv nqaij lossis mus rau hauv cov leeg ua ntej noj mov hauv 20 feeb. Qhov chaw txhaj tshuaj yuav tsum tau hloov tas li, qhov kev txhaj tshuaj tsis tas yuav tsum tau ua haujlwm tas li nyob rau hauv ib thaj chaw ntawm lub cev, tab sis qhov chaw hloov chaw tsuas yog tshwm sim nrog tus kws kho mob, tom qab nws sab laj.

Tseem Ceeb! Nws yog nruj me ntsis txwv tsis pub sib xyaw Insulin Rapid nrog lwm hom tshuaj insulin lossis tshuaj ntawm qhov sib txawv. Rau kev siv, tsuas yog kev daws teeb meem ntawm qhov pom tseeb lossis xim uas tsis muaj qhov pom kev tsis pom kev thiab qhov suav nrog yuav tsum siv.

Cov koob txhaj tshuaj twg yuav tsum tau siv rau kev txhaj tshuaj? Nco ntsoov, koj yuav tsum siv tshuaj yas yas rau kev txhaj tshuaj nkaus xwb, lawv yuav tsum tau tsim tshwj xeeb rau qhov koob tshuaj thiab siab zoo uas yuav siv. Hauv koob txhaj tshuaj yuav tsum tsis muaj lwm yam impurities lossis seem cov tebchaw.

Kev kho mob monotherapy koom tes nrog kev tswj hwm ntawm insulin peb zaug ib hnub nrog kev hloov chaw ntawm kev txhaj tshuaj. Qhov no pab tiv thaiv kev txhim kho ntawm atrophic tshwm sim hauv cov roj ntsha subcutaneous.

Cov lus qhia tshwj xeeb

Cov koob tshuaj yuav tsum tau tsim rau hauv tus account tus yam ntxwv thiab cov kab mob uas yuav tshwm sim, uas suav nrog, ua ntej ntawm:

Rau cov poj niam cev xeeb tub hauv thawj peb lub hlis, txo qis hauv cov tshuaj insulin yog cov yam ntxwv, thiab hauv lub sijhawm tom qab, qhov kev xav tau nce me ntsis. Thaum lub sijhawm yug menyuam thiab nyob rau lub sijhawm ua haujlwm tom qab sijhawm yug menyuam tag, feem ntau xav tau tsawg dua. Rau cov poj niam pub mis niam rau menyuam noj - tshwj xeeb cov kws kho mob xav tau kom txog thaum lub sijhawm ruaj khov, lub sijhawm no tuaj yeem siv sijhawm ntau dua li ib hlis.

Cov neeg mob uas tau txais 100 koob PIECES ntawm cov tshuaj insulin lossis ntau dua toj ib hnub, nyob rau hauv cov xwm txheej ntawm kev hloov tshuaj, cov xwm txheej ntawm lub tsev kho mob yog qhov tsim nyog.

Npaj - analogues

Nqe Insuman Rapid GT kuj yuav txawv raws li thaj av ntawd. Qhov nruab nrab, nws nruab nrab ntawm 1,400 txog 1,600 rubles rau ib pob. Yog lawm, qhov no tsis yog tus nqi qis heev, muab hais tias cov neeg raug yuam kom "zaum" ntawm cov kua dej txhua lub sijhawm.

Cov lus qhia rau kev siv tshuaj

Lub sij hawm rau cov tshuaj insulin thiab cov tshuaj noj yog tsim los ntawm tus kws kho mob koom nrog, uas siv mus rau hauv qhov ntsuas ntawm qab zib thiab qhov hnyav ntawm tus neeg mob lub cev.

Tom qab yuav cov tshuaj, koj yuav tsum nyeem cov lus qhia nyob nrog. Yog tias koj muaj lus nug, koj yuav tsum sab laj nrog koj tus kws kho mob.

Thaum siv yeeb tshuaj, ib qho yuav tsum nruj me ntsis rau cov lus pom zoo tau txais los ntawm tus kws kho mob thiab cov lus pom zoo hauv cov lus qhia rau kev siv.

Cov kev qhia muaj ib qho ua tiav cov xwm txheej uas siv cov tshuaj insulin:

1. ib yam ntshav qab zib uas yuav tsum tau kho tshuaj insulin,
2. kev loj hlob ntawm tus mob ntshav qab zib tsis xeev (ketoacidotic lossis hypersmolar),
3. ketoacidosis - qhov kev ua txhaum ntawm cov metabolism ntawm carbohydrates vim tsis muaj cov tshuaj insulin,
4. ua tiav cov nyiaj them rau cov neeg mob ntshav qab zib uas yuav raug phais lossis thaum ua haujlwm.

Hauv cov lus qhia txuas nrog tsis muaj ntaub ntawv qhia txog kev noj tshuaj, nws tsuas yog kws kho mob sau tseg. Qhov siab tshaj plaws qhov koob tshuaj tsis dhau tshaj li 0.5-1 IU / kg ib hnub. Tsis tas li ntawd, Txoj kev siv tshuaj sai sai yog siv nrog lub cev ntev ntawm cov tshuaj hormones, qhov tshuaj txhua hnub uas tsawg kawg yog 60% ntawm tag nrho cov tshuaj ntawm ob qho tshuaj. Yog hais tias tus neeg mob hloov ntawm lwm cov tshuaj mus rau Insuman Rapid, nws tus mob yuav tsum tau soj ntsuam los ntawm kws kho mob. Koj tuaj yeem qhia lub ntsiab lus tseem ceeb ntawm kev siv cov tshuaj no:

• cov tshuaj yog muab 15-20 feeb ua ntej noj mov,
• kev txhaj tshuaj yog muab subcutaneously thiab intramuscularly,
• qhov chaw rau kev txhaj tshuaj yuav tsum tau hloov tas li
• nrog hyperglycemic coma, ketoacidosis thiab ua tiav cov nyiaj metabolic, cov tshuaj tau muab tshuaj rau txoj leeg,
• cov tshuaj tsis yog siv hauv cov tshuaj insulin,
• 100 IU / ml koob txhaj tshuaj siv rau kev txhaj tshuaj,
• Cov kab mob sai sai tsis yog tov nrog cov tshuaj hormones ntawm tsiaj thiab lwm yam keeb kwm, lwm yam tshuaj,
• ua ntej txhaj tshuaj, tshawb xyuas cov tshuaj, yog tias muaj qee qhov hauv nws - cov lus qhia txwv tsis pub,
• ua ntej kev txhaj tshuaj, huab cua yog coj mus rau hauv cov koob txhaj (qhov ntim yog qhov sib npaug ntawm qhov ntim ntawm insulin), thiab tom qab ntawd tso tawm rau hauv lub vial,
• Cov dej ntim ntawm cov kev xav tau yog sau los ntawm lub raj mis thiab cov npuas raug tshem tawm,
• daim tawv yog tsau thiab cov tshuaj hormones yog maj mam qhia,
• tom qab hle rab koob, rab koob lossis xov paj rwb ntaws ntuav rau ntawm qhov hno,
• hnub tim thawj txhaj koob muaj npe sau rau ntawm lub raj mis.

Cov tshuaj no tau khaws cia rau hauv qhov chaw tsaus nti tsis muaj nkag mus rau cov menyuam yaus me. Kev tso cia qhov kub thiab txias yog 2-8 qib, cov tshuaj yuav tsum tsis txhob txhuam.

Txee lub neej yog 2 xyoos, tom qab lub sijhawm no kev siv cov tshuaj no yog txwv tsis pub.

Cov txheej txheem ua kom tsis xwm yeem, ua kom muaj kev phom sij thiab noj ntau dhau

Cov tshuaj no tsuas muaj ob zaug contraindications - ib tug neeg rhiab rau lub Cheebtsam thiab menyuam yaus hnub nyoog txog ob xyoos.

Qhov kev txwv no vim yog qhov tseeb tias tsis muaj kev tshawb fawb tau ua tiav muaj kev cuam tshuam ntawm cov tshuaj insulin sai rau cov menyuam yaus.

Cov yam ntxwv ntawm yeeb tshuaj yog qhov ua tau ntawm nws txoj kev siv thaum xeeb tub thiab pub niam mis.

Qee zaum, vim kev noj ntau dhau lossis lwm cov laj thawj, cov kev mob tshwm sim ntawm cov tshuaj tshwm sim:

1. Ib lub xeev ntawm cov ntshav ntog ntshav qab zib, cov tsos mob ntawm kev uas tsaug zog, tachycardia, tsis meej pem, xeev siab, thiab ntuav.
2. Lub sijhawm luv ua haujlwm ntawm lub qhov muag pom, qee zaum kev txhim kho ntawm cov teeb meem - cov kab mob ntshav qab zib. Tus kab mob no tshwm sim los ntawm o ntawm cov kab mob retina, uas ua rau daim duab plooj plooj nyob rau hauv pem hauv ntej ntawm lub qhov muag, ntau yam tsis xws luag.
3. Lub ntsej muag rog lossis liab lossis tawv nqaij hauv thaj chaw txhaj tshuaj.
4. Kev ua haujlwm tsis haum ntshav siab yog qhov tsawg. Qhov no tuaj yeem yog angioedema, bronchospasm, txo qis ntshav siab lossis anaphylactic poob siab.
5. Cov txheej txheem ntawm cov tshuaj tiv thaiv rau cov tshuaj tiv thaiv tshaj tawm.
6. Khaws cov tshuaj sodium ntawm tib neeg lub cev, vim qhov tshwm sim ntawm cov tshwm sim ntawm cov nqaij mos o.
7. Txo cov poov tshuaj kom tsawg tsawg hauv lub cev, cov kab mob cerebral edema.

Yog tias tus neeg mob txhaj nws tus kheej nrog ntau dua ntawm cov tshuaj insulin ntau dua li qhov xav tau, hauv txhua txoj kev yuav qhov no yuav ua rau muaj ntshav qab zib hauv ntshav qab zib mellitus. Thaum tus neeg mob nco qab, nws maj nrawm xav noj cov khoom muaj piam thaj ntau, thiab tom qab ntawd nws noj cov khoom noj carbohydrates.

Yog tias tus neeg tsis nco qab lawm, nws tau txhaj koob tshuaj glucagon (1 mg) intramuscularly lossis kua nplaum (20 lossis 30 ml) muab tshuaj. Qhov xwm txheej yog qhov muaj peev xwm ua tau kom rov qab tswj xyuas cov piam thaj hauv qab. Qhov ntau npaum li cas ntawm glucagon los yog piam thaj rau ib tus menyuam yog xam raws nws qhov hnyav.

Pharmacological kev txiav txim

Insuman Rapid muaj cov insulin zoo ib yam hauv cov qauv rau tib neeg insulin thiab tau los ntawm kev tsim kho caj ces siv K12 limtiam E. Coli.

Txo cov ntshav qabzib thiab txhim kho anabolic teebmeem, thiab kuj txo cov teebmeem catabolic,

Nws txhim kho qhov kev thauj ntawm cov kua nplaum mus rau hauv cov hlwb, nrog rau kev tsim cov glycogen hauv cov leeg thiab mob siab, thiab txhim kho kev siv pyruvate. Nws inhibits glycogenolysis thiab glyconeogenesis,

Txhim kho lipogenesis nyob rau hauv daim siab thiab adipose nqaij thiab inhibits lipolysis,

Pab txhawb kom muaj cov amino acids los ntawm cov hlwb thiab ua kom muaj protein synthesis,

Txhawb nqa qhov tau ntawm poov tshuaj los ntawm cov hlwb.

Qhov ua rau lub ntsej muag ntshav tshwm sim nyob rau hauv 30 feeb, thiab nce mus txog qhov siab tshaj plaws hauv 1-4 teev tom qab kev tso tshuaj subcutaneous ntawm cov tshuaj. Cov nyhuv ntev li 7-9 teev.

Cov Tshuaj Pharmacokinetics

Ib nrab-lub neej ntawm cov tshuaj insulin hauv cov ntsiab lus noj qab nyob zoo yog li 4-6 feeb. Hauv kev mob raum tsis ua haujlwm, nws ntev dua.

Nws yuav tsum raug sau tseg tias pharmacokinetics ntawm insulin tsis cuam tshuam nws cov nyhuv metabolic.

Kev Ntsuas Cov Khoom Siv Kev Nyab Xeeb Ua Ntej

Kev kawm txog qhov mob toxicity zoo tau ua tom qab tswjhwm subcutaneous rau cov nas. Tsis pom muaj cov teebmeem mob toxic. Cov kev tshawb fawb ntawm pharmacodynamic teebmeem ntawm subcutaneous cov thawj coj ntawm cov tshuaj mus rau luav thiab dev pom qhov kev xav tias hypoglycemic tshua.

Cev xeeb tub thiab lactation

Tsis muaj kev tshawb nrhiav qhov tseeb txog kev siv cov tshuaj insulin rau tib neeg thaum cev xeeb tub. Cov tshuaj Insulin tsis hla qhov chaw tiv thaiv. Thaum muab tshuaj rau cov poj niam cev xeeb tub, kev ceev faj yuav tsum tau siv.

Nyob rau hauv cov ntaub ntawv ntawm cov neeg mob preexisting los yog mob ntshav qab zib hauv lub cev mellitus, nws yog ib qho tseem ceeb kom tswj tau tus nqi metabolic kom tsim nyog thoob plaws thaum cev xeeb tub. Qhov kev xav tau rau insulin hauv thawj lub hlis ntawm cev xeeb tub yuav txo qis, tab sis nyob rau zaum ob thiab thib peb feem ntau nws nce ntxiv. Tam sim ntawd tom qab yug los, insulin xav kom poob sai (muaj kev pheej hmoo ntawm cov ntshav qog ntshav qab zib tsawg dua). Yuav tsum tau ua tib zoo soj ntsuam ntawm cov ntshav qabzib feem ntau.

Thaum lub sijhawm pub niam mis, tsis muaj kev txwv dab tsi rau kev kho mob insulin. Txawm li cas los xij, cov tshuaj insulin thiab kev noj haus yuav tau ua kom haum.

Sab sij huam

Kev mob ntshav qab zib, feem ntau cov kev mob tshwm sim, tuaj yeem tsim kho yog tias cov koob tshuaj insulin tswj tau tshaj qhov xav tau ntawm nws. Nws tsis tuaj yeem qhia qhov tshwj xeeb tshwm sim ntawm kev mob ntshav qab zib, vim tias tus nqi no hauv kev sim tshuaj thiab nrog kev siv cov tshuaj lag luam yuav txawv nyob ntawm cov pej xeem thiab noj tshuaj. Yog li, nws tsis tuaj yeem qhia txog qhov tsawg zaus. Kev mob ntshav khov ntau heev, tshwj xeeb yog tias lawv rov qab ua dua, tuaj yeem ua rau kev loj hlob ntawm cov tsos mob ntawm lub paj hlwb, nrog rau tsis nco qab, mob plab. Muaj qee kis, qee ntu mob xws li no yuav ua rau neeg tuag taus.

Hauv ntau tus neeg mob, cov cim ntawm hypoglycemic kev puas tsuaj rau lub hauv nruab nrab lub paj hlwb yog ua ntej los ntawm cov cim ntawm adrenergic counterregulation. Raws li txoj cai, ntau dua thiab nrawm dua ntawm cov piam thaj hauv cov ntshav txo, qhov ntau tshaj tawm yog qhov tshwm sim ntawm kev ua haujlwm ntawm kev tawm tsam thiab nws cov tsos mob.

Cov kev mob tshwm sim hauv qab no cuam tshuam nrog kev siv yeeb tshuaj thiab pom nyob rau hauv cov kev tshawb fawb soj ntsuam tau teev los ntawm cov chav kawm ntawm cov kab mob hauv lub cev thiab hauv kev ua kom tsawg zuj zus: muaj ntau (> 1/10), nquag (> 1/100, 1 / 1.000, 1/10000 Tus txheej txheem ntawm kev ua ntawm cov tshuaj

Tau los ntawm kev tshuaj ntsuam genetic engineering, insulin Insuman Rapid GT zoo ib yam li cov tshuaj hormones uas ua los ntawm tib neeg pancreatic beta hlwb. Cov tshuaj tau tawm hauv cov tshuaj uas tsis muaj xim, uas yog txhaj.

Cov tshuaj nquag siv ntawm cov tshuaj yog tib neeg cov tshuaj insulin. Ntxiv rau nws, qhov kev npaj muaj ib qho me me ntawm lwm qhov: glycerol (85%), sodium hydroxide, m-cresol, hydrochloric acid, sodium dihydrogen phosphate dihydrate thiab dej distilled.

Ib nrab ib teev tom qab cov tshuaj hormones nkag mus rau hauv tib neeg lub cev, nws pib ua.Qhov siab tshaj plaws ua rau kev kho mob tuaj dhau 1-3 teev tom qab txhaj tshuaj thiab kav rau 8 teev. Thaum lub sijhawm nws ua, insulin muaj cov teebmeem hauv qab no ntawm lub cev:

• txo hauv cov ntshav qabzib concentration,
• txhim kho cov txiaj ntsig anabolic, uas yog, hloov kho thiab tsim kho cov hlwb tshiab,
• inhibition of catabolic kev ua - kev zom zaub mov metabolic,
• nce qabzib thauj mus rau hauv lub hlwb, tsim cov glycogen hauv lub siab thiab cov leeg,
• kev siv cov piam thaj feem xaus cov khoom lag luam - pyruvates,
• kev tsuj ntawm glycogenolysis, glyconeogenesis thiab lipolysis,
• nce lipogenesis hauv daim ntaub so ntswg thiab cov nplooj siab,
• txhim kho cov poov tshuaj kom tsawg dua hauv qib qis.

Hauv kev xyaum kho mob, Insuman Rapid yog sib xyaw nrog lwm cov tib neeg insulins, uas yog tsim los ntawm Hoechst Marion Roussel, tshwj tsis yog cov tshuaj hormones uas siv rau hauv cov nqus dej.

Kev cuam tshuam nrog lwm yam tshuaj

Thaum lub sij hawm hloov mus rau Insuman Rapid GT, tus kws kho mob ntsuas kev ua siab ntev ntawm cov tshuaj siv cov kev kuaj mob uas tsis muaj kev tiv thaiv kom tsis txhob muaj kev tiv thaiv kab mob. Thaum pib ntawm txoj kev kho, glycemic tawm tsam yog ua tau, tshwj xeeb tshaj yog nyob rau hauv cov neeg mob ntshav qab zib nrog cov ntshav qab zib cov ntsiab lus tsawg.

Kev siv tib lub sij hawm ntawm tib neeg cov tshuaj hormones, hypoglycemic thiab lwm yam kev cuam tshuam tuaj yeem cuam tshuam qhov kev nqis tes ntawm insulin Insuman Rapid hauv txoj kev sib txawv.

Kev siv cov tshuaj tiv thaiv beta-blockers nce ntau txoj kev pheej hmoo ntawm kev tsim lub xeev ntawm cov ntshav qab zib, ntxiv rau, lawv muaj peev xwm los npog nws cov tsos mob. Cov dej cawv haus cawv kuj tseem txo cov ntshav qab zib.

Cov ntshav qabzib tsawg zuj zus ua rau siv cov tshuaj no:

• salicylates, suav nrog acetylsalicylic acid,
• anabolic steroids, amphetamines, txiv neej pw ua ke,
• monoamine oxidase inhibitors (MAO),
• angiotensin hloov mus ua enzyme (ACE) inhibitors,
• suab thaj txo cov tshuaj,
• tetracycline, sulfonamides, trophosphamides,
• cyclophosphamide thiab lwm tus.

Xws li cov tshuaj thiab cov yeeb yaj kiab tuaj yeem tsim kev puas tsuaj rau cov tshuaj insulin thiab nce cov piam thaj hauv cov ntshav:

1. corticotropin,
2. corticosteroids
3. barbiturates
4. danazol
5. glucagon,
6. estrogens, progesterones,
7. nicotinic acid thiab lwm tus.

Kev tawm tsam ntshav ntau ntawm cov ntshav qab zib muaj feem cuam tshuam rau kev mloog zoo, uas yog lub luag haujlwm tseem ceeb hauv kev tswj hwm lub tsheb lossis tsheb. Koj tuaj yeem ua kom cov piam thaj ntxiv yog tias koj noj ib qho qab zib lossis haus cov kua txiv uas qab zib.

Cov xwm txheej zoo li kev noj haus tsis txaus, hla kev txhaj tshuaj, kis kab mob thiab kis kab mob, thiab lub neej kev ua si kuj ua rau muaj suab thaj ntau ntau.

Nqi, tshuaj xyuas thiab analogues

Txhua tus, muaj kws kho mob daim ntawv yuav, tuaj yeem yuav cov tshuaj hauv cov khw muag tshuaj lossis xaj nws online hauv Is Taws Nem. Tus nqi ntawm cov tshuaj insulin nyob ntawm ntau npaum li cas ntawm cov tshuaj daws fwj nyob rau hauv pob. Yeej, tus nqi sib txawv ntawm 1000 txog 1460 Lavxias rubles rau ib pob ntawm cov tshuaj.

Kev ntsuam xyuas ntawm ntau tus neeg mob ntshav qab zib uas tau txhaj tshuaj insulin yog qhov zoo heev. Lawv tau ceeb toom txo qis hauv qab zib cov qib qis dua. Insulin Rapid GT tiag tiag muaj cov nyhuv sai, nws tus nqi kuj qis. Tib qhov tsis zoo ntawm cov tshuaj yog qhov tshwm sim ntawm nws cov kev mob tshwm sim ntawm qhov chaw txhaj tshuaj. Ntau tus tshaj tawm liab thiab khaus ntawm thaj chaw uas tau txhaj tshuaj. Qhov tshwm sim no tuaj yeem tshem tawm los ntawm kev txhaj tshuaj txhua zaus rau lwm qhov chaw lossis lwm qhov chaw.

Feem ntau, ob tus neeg mob thiab kws kho mob suav tias kev npaj tshuaj insulin no ua haujlwm zoo. Cov neeg mob tau txais txiaj ntsig zoo tshaj plaws los ntawm kev kho mob insulin thaum lawv ua raws li kev noj haus uas tsis suav nrog cov khoom noj zom tau yooj yim thiab muaj suab thaj, kev tawm dag zog lub cev thiab tswj lawv lub cev qhov hnyav.

Thaum ib tug neeg tsis kam txais ua ke rau cov tshuaj, tus kws kho mob muaj lub luag haujlwm khaws ib qho insulin ntxiv rau tus neeg mob. Ntawm ntau cov tshuaj, txhais cov ntawv uas muaj tib cov tshuaj nquag tuaj yeem paub qhov txawv. Piv txwv li:

• Actrapid NM
• Biosulin P,
• Rinsulin P,
• Rosinsulin P,
• Humulin Tsis tu ncua.

Qee zaum tus kws kho mob xaiv cov kev kho zoo sib xws uas muaj lwm qhov tseem ceeb, tab sis muaj cov kev kho kom zoo li qub. Qhov no tuaj yeem yog Apidra, Novorapid Penfill, Novorapid Flexspen, Humalog thiab lwm yam tshuaj. Lawv tuaj yeem sib txawv hauv cov ntawv ntau npaum li cas, nrog rau nqi. Piv txwv, tus nqi nruab nrab ntawm cov tshuaj Humalog yog 1820 rubles, thiab pob nyiaj Apidra yog 1880 rubles. Yog li, kev xaiv cov tshuaj yog nyob ntawm ob qho tseem ceeb - qhov ua tau zoo ntawm kev kho mob rau tus neeg mob lub cev thiab nws cov peev nyiaj.

Ntawm ntau cov tshuaj insulin-zoo li, qhov ua tau zoo ntawm Insuman Rapid GT yog qhov ceeb toom. Cov tshuaj no ua rau cov ntshav qab zib tsawg zuj zus mus rau hauv ib qib.

Txij li thaum cov tshuaj muaj qee qhov sib txuam thiab cov kev mob tshwm sim, nws txoj kev siv yog nqa tawm los ntawm kev saib xyuas nruj ntawm tus kws kho mob. Tab sis txhawm rau tshem tawm cov tsos mob ntshav qab zib thiab ua kom lub cev tsis zoo ntawm cov piam thaj, nws tsis yog tsim nyog txhawm rau txhaj tshuaj insulin, tab sis kuj tseem soj ntsuam kom muaj zaub mov noj kom zoo thiab ua lub neej muaj sia. Tsuas yog txoj hauv kev no tuaj yeem ua tus neeg kom ntseeg tau lub neej zoo thiab tag nrho. Daim vis dis aus hauv tsab xov xwm no yuav tham txog qee hom tshuaj insulin.

Cov mob tshwj xeeb

• 1 ml soluble insulin (tib neeg kev tsim tshuaj lom neeg) 3.571 mg (100 IU) Cov Khoom Siv: metacresol (m-cresol) - 2.7 mg, sodium dihydrogen phosphate dihydrate - 2.1 mg, glycerol 85% - 18.824 mg, sodium hydroxide (kom kho pH) - 0.576 mg, hydrochloric acid (los kho pH) - 0.232 mg, dej d / i - txog 1 ml. solulin insulin (tib neeg lub tshuab tsim hluav taws xob) 3.571 mg (100 IU) Cov tsis muaj zog: metacresol (m-cresol), sodium dihydrogen phosphate dihydrate, glycerol 85%, sodium hydroxide (los kho pH), hydrochloric acid (los kho pH), dej / thiab. solulin insulin (tib neeg lub tshuab tsim hluav taws xob) 3.571 mg (100 IU) Cov tsis muaj zog: metacresol (m-cresol), sodium dihydrogen phosphate dihydrate, glycerol 85%, sodium hydroxide (los kho pH), hydrochloric acid (los kho pH), dej / thiab.

Kev Ua Phem Rau Neeg Mob sai

• - hauv txoj kev kho mob nyuaj rau qee qhov qaug dab peg, nrog lossis tsis muaj theem nrab dav dav, hauv cov neeg mob vwm uas muaj hnub nyoog 16 xyoo thiab laus dua Wimpat® nyob rau hauv daim ntawv ntawm infusions yog tus kws kho mob thaum cov tshuaj ib ntus tsis tuaj yeem nqa mus rau sab hauv

Insuman sai heev GT contraindications

• - Cov ntshav qog ntshav qab zib, - kev tsis haum lub cev tsis haum rau cov tshuaj insulin lossis rau ib qho twg ntawm cov tshuaj tiv thaiv cov tshuaj. Nrog kev ceev faj, cov tshuaj yuav tsum tau siv thaum lub raum tsis ua haujlwm (kev txo qis hauv insulin vim qhov txo qis hauv insulin metabolism yog qhov ua tau), hauv cov neeg mob laus (kev txo qis ntawm lub raum ua haujlwm tuaj yeem ua rau txo qis hauv insulin qhov xav tau), hauv cov neeg mob uas tsis muaj kabmob hepatic (insulin yuav tsum tau txo vim muaj kev txo qis hauv lub peev xwm gluconeogenesis thiab txo qis hauv kev ua haujlwm ntawm insulin metabolism), hauv cov neeg mob uas mob hnyav ntawm lub plawv thiab cov hlab ntsha hauv lub cev (hypog kev muaj mob hauv lub cev yuav muaj qhov tshwj xeeb hauv kev kho mob, vim tias muaj kev pheej hmoo ntawm lub plawv lossis mob hlwb ntau dua ntawm cov ntshav qog nqaij hlav hauv cov neeg mob uas muaj kev mob hlwb (tshwj xeeb tshaj yog cov uas tsis tau txais kev kho mob nrog photocoagulation (kho laser), vim tias lawv muaj kev pheej hmoo ntawm amaurosis nrog ua kom tiav hypoglycemia - ua tiav qhov muag tsis pom kev) ,

Kev mob tshwm sim ntawm Insuman Rapid GT

• Kev mob ntshav qab zib ntshav siab heev Hypoglycemia, feem ntau cov kev phiv los ntawm cov tshuaj insulin, tuaj yeem txhim kho yog tias cov koob tshuaj insulin tau tshaj li qhov xav tau rau nws. Kev rov qab mob hnyav dua ntawm cov ntshav qog ntshav qab zib tuaj yeem ua rau kev loj hlob ntawm cov tsos mob ntawm lub paj hlwb, nrog rau tsis nco qab, mob ntswj.Lub caij nyoog ntev los sis mob ceev heev ntawm cov ntshav qab zib hauv lub siab tuaj yeem tsim kev hem thawj rau neeg txoj sia. Hauv ntau tus neeg mob, cov tsos mob thiab cov tsos mob ntawm tus mob neuroglycopenia ua ntej los ntawm cov tsos mob ntawm tus mob reflex (hauv kev teb rau kev txhim kho hypoglycemia) kev ua haujlwm ntawm lub siab xav ntawm lub hlwb. Feem ntau, nrog hais tawm ntau dua los yog nrawm dua qub nyob rau hauv kev mloog zoo ntawm cov piam thaj hauv cov ntshav, qhov tshwm sim ntawm kev rov ua dua ntawm lub siab xav ntawm lub cev thiab nws cov tsos mob tshwm sim ntau dua. Nrog lub ntsej muag txo qis hauv cov concentration ntawm cov piam thaj hauv cov ntshav, kev txhim kho ntawm hypokalemia (mob los ntawm cov hlab plawv) lossis kev txhim kho ntawm cerebral edema tau. Cov hauv qab no yog cov kev tshwm sim tsis zoo uas tau pom hauv qhov kev sim kho mob uas tau faib los ntawm cov chav hauv nruab nrog cev thiab hauv kev ua kom tsawg zuj zus: feem ntau (? 1/10), feem ntau (? 1/100 thiab

Cia rau cov neeg mob

• cia rau hauv qhov chaw qhuav
• Khaws rau hauv qhov txias (t 2 - 5)
• txav deb ntawm menyuam yaus
• muab cia rau hauv qhov chaw tsaus

• Brinsulrapi MK, Brinsulrapi Ch, Insulin Actrapid, Levulin

Kev siv tshuaj ntshav siab yog tsim rau cov ntshav qab zib. Kev kho tshuaj Insulin tso cai rau koj kho koj cov ntshav qab zib. Cov tshuaj pab pawg no suav nrog Insuman Rapid GT.

Soluble insulin (tib neeg kev paub txog engineering).

Tso cov ntaub ntawv thiab cov nyob ua ke

Kev daws yog muaj nyob rau hauv vials lossis cartridges. Ntim nrog Solostar pov tseg injector yog tau ua tiav.

Cov nquag ua yeeb yam hauv cov kua yog tib neeg lub cev. Qhov concentration ntawm kev daws yog 3.571 mg, lossis 100 IU / 1 ml.

Yuav ua li cas coj Insuman Rapid GT

Txoj kev daws teeb meem yog npaj rau kev ua dej num thiab ntu hauv av. Tsis muaj ib yam kev cai tswj hwm kev haus tshuaj. Txoj kev kho yuav tsum yog kho los ntawm tus kws kho mob. Cov neeg mob sib txawv muaj ntau qib sib txawv ntawm cov piam thaj uas tsim nyog los tswj, yog li cov tshuaj thiab cov tshuaj kho tau suav nrog tus kheej. Tus kws kho mob uas tuaj koom yuav siv sij hawm mus ua tus neeg mob lub cev ua ub no thiab tus yam ntxwv noj haus.

Qhov yuav tsum tau hloov qhov tshuaj ntau npaum li cas yuav tshwm sim hauv qee kis:

1. Thaum hloov cov tshuaj nrog lwm hom insulin.
2. Nrog rau kev nkag siab zoo ntxiv rau cov tshuaj vim tias txhim kho metabolic tswj.
3. Thaum poob lossis nce phaus ntxiv los ntawm tus neeg mob.
4. Thaum kho cov khoom noj khoom haus, hloov qhov sib zog ntawm lub nra.

Subcutaneous kev tswj hwm yog qhov tob. Nws raug nquahu kom ua qhov txheej txheem 15 lossis 20 feeb ua ntej noj mov. Nws yog ib qho tsim nyog yuav tau hloov qhov chaw txhaj tshuaj nrog txhua qhov kev txhaj tshuaj. Txawm li cas los xij, nyob ntawm thaj tsam ntawm kev tswj hwm kev daws teeb meem, pharmacokinetics ntawm cov tshuaj yuav hloov pauv, yog li kev hloov thaj tsam ntawm kev tswj hwm yuav tsum pom zoo nrog tus kws kho mob.

Nws yog ib qho tsim nyog yuav tsum them sai sai rau qhov muaj lub hau. Qhov no qhia tau hais tias kev ncaj ncees ntawm lub thawm. Tsis muaj cov xaim yuav tsum muaj nyob hauv cov tshuaj, cov kua yuav tsum yog pob tshab.

Cov hauv qab no yuav tsum tau txiav txim siab:

1. Thaum siv txoj hauv kev daws teeb meem, siv cov kua yas uas haum.
2. Ua ntej, huab cua yog sau hauv cov koob txhaj, qhov ntau npaum li cas ntawm qhov sib npaug ntawm cov tshuaj. Nkag mus rau hauv qhov chaw khoob hauv lub raj mis. Peev xwm yog muab pauv. Txheej txheej ntawm kev daws teeb meem yog nqa tawm. Yuav tsum tsis muaj cua npuas ntxiv rau hauv cov koob txhaj tshuaj. Maj mam nkag mus rau kev daws rau hauv daim tawv nqaij quav tsim los ntawm cov ntiv tes.
3. Ntawm daim ntawv lo koj yuav tsum tau qhia hnub tim uas tau tsim thawj koob tshuaj.
4. Thaum siv daim cartridges, yuav tsum siv cov tshuaj txhaj (koob txhaj tshuaj).
5. Daim cartridge raug pom zoo kom muab sab laug ntawm chav sov li 1 lossis 2 teev, raws li qhia txog muab cov khoom ua kom chilled mob. Ua ntej kev txhaj tshuaj, huab cua yuav tsum tau muab tshem tawm.
6. Lub ntim roj ntim tsis tau ntxiv.
7. Nrog tus cwj mem tsis ua hauj lwm-xem, cov koob txhaj tshuaj haum yog tso cai.

Qhov seem ntawm seem ntawm lwm cov tshuaj hauv koob txhaj tshuaj yog qhov tsis lees txais.

Ntawm ib feem ntawm cov plab hnyuv siab raum ntawm lub zeem muag

Tshaj tawm kev hloov pauv hauv kev tswj glycemic tuaj yeem ua rau kev ntxhov siab ib ntus ntawm cov cell membrane ntawm lub lens ntawm lub qhov muag, qhov hloov pauv ntawm qhov ntsuas qhov ntsuas rov qab. Qhov kev hloov pauv ntawm qhov ntsuas tau vim tias siv zog ntau ntawm kev kho mob yuav nrog rau kev cuam tshuam ib ntus hauv cov xwm txheej ntawm retinopathy.

Hauv cov ntshav qog ntshav qab zib nrog kev loj hlob ntawm lub hlwb retinopathy, kev puas tsuaj rau retina lossis cov hlab qhov muag ntawm lub qhov muag pauv tau.

Contraindicated kev sib txuas ua ke

Kev sib xyaw ua ke ntawm cov tshuaj nrog tsiaj insulin thiab analogues tsis suav nrog.

Kev sib koom tes ntawm Pentamidine ua rau txoj kev txhim kho ntawm cov teeb meem.

Cov tshuaj yeeb dej hauv qab no thiab kev npaj ua kom tsis txhob muaj cov qab zib-txo cov nyhuv:

• corticosteroids
• adrenocorticotropic lawm,
• derivatives ntawm phenothiazine thiab phenytoin,
• glucagon,
• poj niam txiv neej cov tshuaj hormones,
• kev loj hlob lawm,
• nicotinic acid
• phenolphthalein,
• tshuaj kho mob
• tshuaj uas cuam tshuam rau lub paj hlwb,
• hluavtaws androgen Danazole,
• tshuaj tiv thaiv TB yog Isoniazid,
• adrenoblocker Doxazosin.

Sympathomimetics thiab iodinated tyrosine derivatives tsis muaj zog ua yeeb yam ntawm kev daws.

Tej kev sib txuam uas xav tau ceev faj

Cov tshuaj hauv qab no ua rau kev pheej hmoo txaus ntshai:

• endrogens thiab anabolics,
• ib tug xov tooj ntawm cov tshuaj rau kev kho mob ntawm lub plawv thiab leeg ntshav tsis zoo,
• CNS stimulants,
• tshuaj tiv thaiv cybenzoline,
• propoxyphene analgesic,
• Pentoxifylline angioprotector,
• cytostatic tshuaj trophosphamide,
• tus lej ntawm cov tshuaj tiv thaiv kab mob
• sulfonamides,
• ib tug xov tooj ntawm cov tshuaj tswj rau txos roj,
• tetracycline tshuaj tua kab mob,
• npaj raws li somatostatin thiab nws cov analogues,
• cov kab mob hypoglycemic
• qab los noj mov fenfluramine,
• antitumor tshuaj ifosfamide.

Kev ceev faj yuav tsum tau noj tshuaj raws li esters ntawm salicylic acid, tritokvalin, cyclophosphamide, guanethidine thiab phentolamine.

Lithium ntsev yuav ua tau attenuate lossis txhim kho cov nyhuv ntawm cov tshuaj. Reserpine thiab clonidine sib txawv hauv tib qho kev ua.

Kev siv cov beta-blockers nce qhov kev pheej hmoo ntawm cov teeb meem.

Cawv tau zoo

Hauv cov cawv quav cawv ntev, qhov kev hloov pauv ntawm glycemia. Mob ntshav qab zib, kev haus cawv haus tsawg, thiab kws kho mob sab laj yog ib qho tseem ceeb rau kev haus dej haus cawv muaj kev nyab xeeb. Glucose concentration tuaj yeem ua rau poob rau ib qib tseem ceeb.

Tom qab siv thawj zaug, lub raj mis muaj peev xwm muab khaws cia rau 4 teev, daim cartridge - rau 28 hnub tom qab kev teeb tsa. Thaum lub sijhawm khaws cia, kev kov lub teeb yuav tsum raug zam thiab qhov kub thiab txias yuav tsum tsis pub nce siab tshaj + 25 ° C.

Chaw tsim tshuaj paus

Cov tshuaj yog lub tsev tsim los ntawm Sanofi-Aventis. Lub teb chaws ntawm kev tsim khoom siv yog lub teb chaws Yelemees lossis Russia.

Insulin npaj Insuman sai thiab Insuman Bazal

Cov cuab yeej no hais txog cov tshuaj uas siv rau cov neeg mob ntshav qab zib. Cov chaw tsim khoom yog Fabkis lub tuam txhab tshuaj.

Cov yam ntxwv ntawm cov tshuaj yog dab tsi, siv li cas kom raug, nws muaj txiaj ntsig zoo dua lwm cov tshuaj, thiab nws tau qhia rau txhua tus neeg mob? Muaj ntau cov lus nug, tab sis rau txhua ntawm lawv koj tuaj yeem nrhiav lo lus teb hauv kab lus no.