Espa Lipon (600 mg

Raws li cov lus qhia rau Espa-Lipon, cov tshuaj muaj detoxification, hypoglycemic, hypocholesterolemic thiab hepatoprotective kev ua haujlwm, koom tes hauv cov kev cai ntawm cov metabolism. Thioctic acid, uas yog ib feem ntawm Espa-Lipon, yog koom nrog oxidative cov tshwm sim ntawm alpha-keto acids thiab pyruvic acid, txhim kho daim siab ua haujlwm, thiab txhawb cov metabolism hauv roj.

Los ntawm qhov kev nqis tes ua, thioctic acid zoo ib yam li cov vitamins ntawm pab pawg B. Espa-Lipon pab txhawm rau nce glycogen hauv daim siab ua haujlwm, txo qis cov ntsiab lus ntawm cov piam thaj hauv cov ntshav, thiab kov yeej kev ua txhaum ntawm kev muaj peev xwm ntawm cov hlwb ua rau kev ua haujlwm ntawm insulin. Cov tshuaj pab tshem tawm cov co toxins hauv lub cev, tiv thaiv lub siab ua haujlwm los ntawm cov tshuaj lom, tiv thaiv lub cev thaum muaj tshuaj lom nrog ntsev ntawm cov hlau nyhav.

Cov nyhuv neuroprotective ntawm Espa-Lipon yog los tiv thaiv lipid peroxidation hauv cov hlab ntsha cov hlab ntsha, ua kom cov ntshav endoneural txaus, thiab pab txhawb cov txheej txheem ntawm kev ua cov hlab ntaws mus rau lub hlwb.

Noj cov tshuaj hauv cov neeg mob uas lub cev muaj zog neuropathy, raws li kev tshuaj xyuas ntawm Espa-Lipon, ua rau pom qhov tshwm sim ntawm cov neeg coob ntawm cov macroergic tebchaw hauv cov leeg.

Thaum noj ntawm qhov ncauj, Espa-Lipon zoo thiab sai sai los ntawm lub plab zom mov, thiab kev siv tshuaj ib txhij nrog cov zaub mov txo qhov nrawm thiab zoo ntawm kev nqus ntawm cov tshuaj.

Kev txhim kho ntawm thioctic acid yog nqa los ntawm kev sib txuas thiab sib xyaw ntawm cov leeg ib sab. Cov tshuaj nquag ua si Espa-Lipon raug ntuav tawm hauv cov zis hauv daim ntawv ntawm metabolites. Ib nrab-lub neej ntawm cov tshuaj los ntawm cov ntshav ntshav yog 10-20 feeb.

Espa-Lipon muaj cov txiaj ntsig "dhau los" los ntawm lub siab - uas yog, cov khoom ua haujlwm nquag ntawm cov tshuaj yog qee yam qis qis los ntawm tus neeg tiv thaiv ib txwm los ntawm cov tshuaj txawv teb chaws nkag mus rau hauv lub cev.

Dosage daim ntawv

Mloog zoo rau kev daws rau kev lis ntshav 600 mg / 24 ml

24 ml thiab 1 ml ntawm cov tshuaj muaj

cov tshuaj heev: thioctic acid nyob rau hauv 24 ml-600.0 mg thiab 1 ml-25.0 mg

hauvtus pabse tshuaj yeeb dej cawa: ethylenediamine, dej rau kev txhaj tshuaj.

Cov kua pob tshab los ntawm lub teeb daj mus rau xim daj ntsuab.

Cov chaw muag tshuaj

Cov Tshuaj Pharmacokinetics

Xuas. Nrog kev tswj hwm lub sijhawm, lub sijhawm kom mus txog qhov siab tshaj plasma ntshav yog 10-11 feeb, qhov siab tshaj plaws yog 25-38 μg / ml, thaj chaw hauv qab-ua haujlwm nkhaus yog li 5 μg h / ml. Bioavailability yog 100%.

Kev zom zaub mov: Thioctic acid ua rau cov "ua ntej dhau" los ntawm lub siab.

Faib: qhov ntim ntawm kev faib tawm yog li 450 ml / kg.

Thim: thioctic acid thiab nws cov metabolites yog cov tawm ntawm cov raum (80-90%). Qhov kev tshem tawm ib nrab-lub neej yog 20-50 feeb. Tag nrho cov ntshav tshem tawm yog 10-15 feeb.

Cov Tshuaj Hauv Tshuaj

Espa-lipon - ib qho kev tiv thaiv tsis zoo (khi dawb radicals), yog tsim nyob rau hauv lub cev los ntawm oxidative decarboxylation ntawm alpha-keto acids. Raws li coenzyme ntawm mitochondrial multienzyme complexes, nws koom nrog oxidative decarboxylation ntawm pyruvic acid thiab alpha-keto acids. Nws pab txhawm rau txo qis kev mloog ntawm cov piam thaj hauv cov ntshav thiab nce glycogen hauv lub siab, ntxiv rau kov yeej cov tshuaj insulin. Los ntawm qhov kev txiav txim siab biochemical, nws yog nyob ze rau cov vitamins B. Koom rau hauv kev tswj hwm kev ua haujlwm ntawm lipid thiab carbohydrate, txhawb cov roj cholesterol, txhim kho daim siab ua haujlwm, txo cov kev puas tsuaj ntawm cov tshuaj lom thiab ua tsis tau zoo rau nws. Txhim kho trophic neurons.

Cov Tshuaj Hauv Tshuaj

Thioctic acid — antioxidant, uas yog tsim nyob rau hauv lub cev los ntawm decarboxylation ntawm alpha-keto acids. Nws muaj cov nyhuv zoo li B vitaminsCov. Nws lub luag haujlwm hauv lub zog hauv lub cev metabolism, tswj cov lipid (cov metabolism hauv roj) thiab cov metabolism hauv cov metabolism. Kev qiv tawm lipotropicthiab detoxification nyhuvCov. Ntxim rau carbohydrate metabolism ua rau nce ntxiv glycogennyob rau hauv daim siab thiab txo qis piam thajhauv cov ntshav.

Nws pab txhim kho trophism ntawm neurons, vim nws nthuav tawm hauv lawv thiab txo cov ntsiab lus ntawm cov dawb radicals thiab daim siab ua haujlwm (nrog rau chav kawm ntawm kev kho mob).

Kev qiv tawm lipid-txos, tshuaj qog ntshav, hepatoprotectivethiab cov nyhuv hypocholesterolemic.

Tsuas tshuaj thiab tswj hwm

Thaum pib ntawm kev kho mob, cov tshuaj yog tswj niam txiv. Tom qab, thaum ua txoj kev kho kev saib xyuas, lawv hloov mus rau kev noj tshuaj hauv.

Mloog zoo rau kev daws rau infusion:

Cov tshuaj yog muab tshuaj rau hauv daim ntawv ntawm infusions tom qab ua ntej dilution hauv 200-250 ml ntawm isotonic sodium tshuaj dawb tov.

Ntawm Cov foos hnyav ntawm cov mob ntshav qab zib polyneuropathy cov tshuaj yog muab ib hnub ib zaug tso rau hauv ib qho poob ntawm 24 ml ntawm cov tshuaj hauv ib qho isotonic sodium chloride tov (uas sib haum rau 600 mg ntawm thioctic acid hauv ib hnub). Lub sijhawm tiv thaiv ntawm Txoj kev lis ntshav yog 30 feeb. Lub sijhawm tiv thaiv ntawm kev lis ntshav txoj kev kho yog 5-28 hnub.

Npaj Txoj kev lis ntshav cov kev daws teeb meem yuav tsum tau muab cia rau hauv qhov chaw tsaus thiab siv tsis dhau 6 teev tom qab kev npaj. Thaum lub sij hawm Txoj kev lis ntshav yuav tsum qhwv lub raj mis nrog ntawv tsaus. Tom ntej no, koj yuav tsum hloov mus rau kev saib xyuas kev kho mob hauv daim ntawv ntawm cov ntsiav tshuaj ntawm koob tshuaj ntawm 400-600 mg ib hnub. Lub sijhawm tsawg kawg nkaus ntawm kev kho mob hauv cov ntsiav tshuaj yog 3 hli.

Qee qhov xwm txheej, kev noj cov tshuaj cuam tshuam nrog kev siv ntev dua, lub sijhawm uas txiav txim los ntawm tus kws kho mob koom nrog.

Sab sij huam

- Ua pob rau ntawm daim tawv nqaij, urticaria, khaus

- cov kev tsis haum tshuaj tawm rau lub cev (anaphylactic shock)

xeev siab, ntuav, hloov saj

-paus hemorrhage, nyiam kev los ntshav

platelet ua hauj lwm

-zoo ntxiv rau hauv qab zib cov qib (vim tias txhim kho cov piam thaj hauv siab), tej zaum yuav nrog nws kiv taub hau, ntau qhov muag pom kev tsis zoo, tawm hws

- mob taub hau (dhau mus nthawv), muaj zog intracranial siab, ua pa nyuaj (tom qab kev tso ntshav sai)

Cov tshuaj sib cuam tshuam

Nrog rau kev siv ua ke ntawm Espa-Lipon nrog cov tshuaj insulin thiab tshuaj tiv thaiv kab mob hauv lub qhov ncauj, qhov ntxim nyiam hypoglycemic ntawm tom kawg yog qhov txhim kho.

Thioctic acid cov ntaub ntawv nyuaj nyuaj ua kom yooj yim nrog cov suab thaj (piv txwv li, kev daws teeb meem ntawm levulose).

Txoj kev daws teeb meem yog tsis sib haum nrog cov kua dej qab zib, Lub hauv paus kev daws teeb meem, nrog rau cov kev daws teeb meem uas tuaj yeem sib cuam tshuam nrog SH-pawg lossis cov choj disulfide.

Thioctic acid (raws li kev daws rau Txoj kev lis ntshav) txo cov nyhuv ntawm cisplatin.

Kev noj zaub mov zoo tib yam ntawm cov hlau, magnesium, calcium uas muaj cov khoom noj siv mis nyuj tsis pom zoo (noj tsis pub ntxov dua 6-8 teev tom qab kev siv tshuaj yeeb).

Cov lus qhia tshwj xeeb

Thaum nqa tawm Espa-Lipon txoj kev kho hauv cov neeg mob ntshav qab zib mellitus, tshwj xeeb tshaj yog thaum pib kho, tsis tu ncua (raws li kws kho mob pom zoo) kev saib xyuas cov ntshav qabzib yog tsim nyog. Qee qhov xwm txheej, yuav tsum tau txhaj tshuaj kom tsawg ntawm cov kab mob hypoglycemic.

Thaum kho, nws yog ib qho tsim nyog yuav tsum txwv tsis pub haus dej cawv, txij li kev kho kom thioctic acid tsis muaj zog.

Kev daws rau Txoj kev lis ntshav yog muab tshuaj rau hauv lub cev, namely nyob rau hauv 2-4 lub lis piam hauv thawj theem ntawm kev kho mob.

Rau kev tswj hwm kev ncaj qha, cov ntsiab lus ntawm Espa-Lipon 600 mg ampoule yog diluted nrog 250 ml ntawm 0.9% sodium chloride tov, nyob rau hauv daim ntawv ntawm luv luv-infusion rau tsawg kawg 30 feeb.

Vim lub siab hnyav dhau los ntawm cov tshuaj nquag, ib qho kev sib xyaw infusion yuav tsum tau npaj tam sim ua ntej kev tswj hwm, ampoules yuav tsum tau muab tshem tawm ntawm lub ntim tsuas yog ua ntej siv, lub vial yuav tsum muab qhwv nrog ntawv dub thaum lub sijhawm infusion. Lub txee lub neej ntawm kev daws teeb meem npaj rau siv tom qab daws nrog ib qho tshuaj sodium istonic sodium chloride ntau yog 6 teev thaum khaws cia hauv qhov chaw tsaus.

Cev xeeb tub thiab lactation

Vim tias qhov kev paub tsis txaus nrog rau kev siv tshuaj, Espa-Lipon tsis tau raug sau tseg rau cov poj niam cev xeeb tub.

Nws tsis pom zoo kom siv cov tshuaj thaum lactation, raws li tsis muaj ntaub ntawv qhia txog kev muaj peev xwm los ntawm cov tshuaj nrog niam mis.

Muaj feem xyuam rau lub peev xwm ntawm kev tsav tsheb lossis cov tshuab muaj khoom txaus ntshai

Muab cov kev mob tshwm sim uas yuav tshwm sim (convulsions, diplopia, kiv taub hau), yuav tsum tau saib xyuas thaum tsav tsheb lossis ua haujlwm nrog lub tshuab txav.

Noj ntau dhau

Cov tsos mob mob taub hau, xeev siab, ntuav.

Kev noj tshuaj ntau dhau tuaj yeem ua rau cov chaw kuaj mob ua rau qaug cawv nrog kev hloov pauv hauv lub hauv nruab nrab cov hlab hlwb (kev ntxhov siab thiab kev tsis haum xeeb), cov kab mob lactic acidosis, mob ntshav qab zib, thiab kev txhim kho ntawm DIC.

Kev Kho Mob: kev kho mob, yog tias tsim nyog - kho cov tshuaj tiv thaiv kev tiv thaiv, ntsuas kom ua haujlwm ntawm cov haujlwm tseem ceeb. Tsis muaj ib qho tshuaj tua kab mob tshwj xeeb.

Daim Ntawv Tso Npe Sau Npe

Esparma GmbH, Seepark 7, 39116 Magdeburg, Lub Tebchaws Yelemees

Chaw nyob ntawm lub koom haum uas lees txais ntawv thov nyiaj los ntawm cov neeg siv khoom ntawm cov khoom lag luam zoo hauv Republic of Kazakhstan

Tus sawv cev chaw haujlwm ntawm Pharma Garant GmbH

Zhibek Zholy 64, off.305 Almaty, Kazakhstan, 050002

Kev qhia rau siv Espa-Lipona

Raws li cov lus qhia, Espa-Lipon tau sau tseg rau cov neeg mob hauv qab no:

• Polyneuropathies (suav nrog rau tus mob ntshav qab zib thiab haus dej cawv tshuaj),
• Cov kab mob siab (nrog rau mob qog thiab mob rau daim siab ntev),
• Mob nyhav ntev los yog mob hnyav ua rau cuam tshuam nrog kev haus dej nrog cov ntsev ntawm cov hlau nyhav, nceb, thiab lwm yam.

Tsis tas li, cov tshuaj muaj tshuaj tiv thaiv atherosclerosis, siv rau kev kho mob thiab tiv thaiv cov kab mob arterial.

Cov Yuav Tsum Muaj

Espa-Lipon tsis yog cov kws kho mob rau cov neeg mob uas muaj kev tiv thaiv kev quav cawv, muaj cov ntshav qabzib-galactose malabsorption syndrome, zoo li cov neeg muaj mob tsis txaus rau lub cev.

Nrog ceev faj, kev siv ntawm Espa-Lipon raug pom zoo rau cov neeg mob ntshav qab zib mellitus - nrog rau kev kho qhov yuav tsum tau txhaj ntawm cov koob tshuaj hypoglycemic. Cov menyuam yaus yuav tsum tsis txhob hla Espa-Lipon kev kho mob rau cov menyuam yaus hnub nyoog qis dua 18 xyoo - vim tsis muaj ntaub ntawv qhia txog kev nyab xeeb ntawm kev siv tshuaj rau cov neeg mob no. Yog tias muaj cov cim tseem ceeb, cov tshuaj no tuaj yeem nqa los ntawm cov neeg hauv pab pawg hnub nyoog nruj me ntsis raws li kws kho mob pom zoo, suav rau hauv tus kheej qhov ntau npaum li cas.

Kev nyab xeeb tag nrho ntawm Espa-Lipon rau kev noj qab haus huv ntawm menyuam hauv plab thaum noj cov tshuaj thaum cev xeeb tub kuj tseem tsis tau muaj pov thawj. Yog tias nws yuav tsum tau kho tus poj niam nrog Espa-Lipon thaum lactation, nws yog qhov yuav tsum tau los daws qhov teebmeem ntawm kev tu menyuam tsis pub mis ib ntus ntawm lub mis.

Yeeb tshuaj sib cuam tshuam

Kev tswj hwm tib lub sijhawm ntawm Espa-Lipon nrog qhov ncauj tshuaj hypoglycemic thiab insulin tuaj yeem ua rau muaj qhov nce ntawm cov nyhuv hypoglycemic - kev nce siab ntawm cov kab mob ntawm cov nqaij hauv lub cev mus rau insulin.

Kev siv ntawm Espa-Lipon raws li cov lus qhia ua ke nrog ethyl cawv txo cov haujlwm thioctic acid. Lub sijhawm kho mob nrog cov tshuaj, nws raug nquahu kom tsis txhob noj cov khoom uas muaj cawv thiab haus cawv.

Tsis tas li ntawd, cov kev ua ntawm thioctic acid nrog rau kev sib khi hlau tau pom, yog li ntawd, kev siv ntawm Espa-Lipon ib txhij nrog cov tshuaj muaj hlau, calcium, calcium ions muaj peev xwm nrog ob teev nyob nruab nrab ntawm cov koob tshuaj.

Noj Espa-Lipon nrog cisplatin txo cov tshuaj ua tau zoo.

Espa-Lipon, cov lus qhia rau kev siv (Txoj kev thiab ntau npaum li cas)

Feem ntau, kev kho pib nrog iv infusions, tom qab ntawd hloov mus rau Espa-Lipon ntsiav tshuaj. Cov ntsiav tshuaj tau noj ntawm qhov ncauj, tsis tau ntxo, 30 feeb ua ntej noj mov 1 zaug hauv ib hnub. Cov koob tshuaj txhua hnub yog 600 mg. Lub 3 hli muaj kev cob qhia Raws li kws kho mob sau tseg, cov tshuaj no tuaj yeem siv sijhawm ntev.

Ntawm mob ntshav qab zib xav tau kev tswj hwm piam thajhauv cov ntshav. Thaum kho lub sijhawm, siv tsis suav nrog dej cawvuas attenuates cov nyhuv ntawm cov tshuaj.

Kev sib txuam

Ib qho kev nce hauv cov nyhuv hypoglycemic yog sau tseg thaum siv nrog tshuaj insulin los yog qhov ncauj tshuaj hypoglycemic.

Txo qhov ua hauj lwm zoo Cisplatin sijhawm mus ntsib nrog thioctic kua qaub.

Ethanolua kom tsis muaj teebmeem txog cov tshuaj.

Txhim kho anti-inflammatory nyhuv GKS.

Binds hlau, yog li ntawd hlau npaj tsis tuaj yeem muab tso rau tib lub sijhawm. Txais tos cov tshuaj no tau muab faib rau hauv lub sijhawm (2 teev).

Espa Lipon tshuaj xyuas

Tsis muaj ntau qhov kev txheeb xyuas txog kev siv cov tshuaj no, vim tias Espa-Lipon tsis tshua siv los ua kev kho mob monotherapy. Feem ntau feem ntau muaj kev txheeb xyuas txog nws qhov kev siv hauv mob ntshav qab zib polyneuropathyCov. Cov neeg mob nco ntsoov tias kev txais tos ntev ntev tau pab tshem tawm qhov mob ntawm ob txhais ceg thiab txhais taw, qhov hnov ​​mob, "txhaws qa", mob plab thiab rov zoo dua.

Ntawm rog ua daim siab mob ntshav qab zib cov tshuaj pab rau cov kua tsib tso pa tawm thiab tshem tawm cov tsos mob dyspeptic. Kev txhim kho cov neeg mob tau lees paub los ntawm kev soj ntsuam (ua haujlwm li qub transaminase) thiab qhov raug zoo ntawm cov cim ultrasound.

Muaj cov pov thawj thaum Espa-Lipon tau ua tiav kev siv ntse hauv kev kho atherosclerosis.

Hauv txhua qhov xwm txheej, kev kho mob pib nrog kev tswj hwm drip (10-20 cov neeg mob me me) hauv tsev kho mob, thiab tom qab ntawd cov neeg mob tau noj cov ntsiav tshuaj, qee zaum kev noj tshuaj txhua hnub yog 1800 mg (3 ntsiav tshuaj).

Ntawm cov kev mob tshwm sim, xeev siab thiab kub siab tau sau tseg thaum noj tshuaj thiab thrombophlebitis nrog kev tswj hwm intravenous.

Lub Npe:

Espa-Lipon (tov rau txhaj) (Espa-Lipon)

1 ampoule ntawm Espa-Lipon 300 muaj:
Ethylene bisatsan-ntsev cov tshuaj alpha lipoic acid (nyob rau hauv alpha lipoic acid) - 300 mg,
Cov muaj mob: dej rau kev txhaj tshuaj.

1 ampoule ntawm Espa-Lipon 600 muaj:
Ethylene bisatsan-ntsev cov tshuaj alpha lipoic acid (nyob rau hauv alpha lipoic acid) - 600 mg,
Cov muaj mob: dej rau kev txhaj tshuaj.

Cev xeeb tub

Lub sijhawm no, tsis muaj ntaub ntawv ntseeg tau txog kev nyab xeeb ntawm kev siv tshuaj Espa-Lipon thaum cev xeeb tub. Cov tshuaj tuaj yeem tsim tawm thaum cev xeeb tub los ntawm tus kws kho mob tuaj koom yog tias qhov tsim nyog tau txais txiaj ntsig rau leej niam ua rau muaj kev pheej hmoo ntau rau cov menyuam hauv plab.
Yog tias nws yuav tsum tau siv cov tshuaj thaum lactation, nws yog qhov yuav tsum tau sab laj nrog koj tus kws kho mob thiab txiav txim siab txog qhov cuam tshuam ntawm kev pub mis niam.

Cia rau cov neeg mob

Cov tshuaj tau pom zoo kom khaws cia rau hauv qhov chaw qhuav kom deb ntawm kev tshav ntuj ncaj qha ntawm qhov kub ntawm 15 txog 25 degrees Celsius. Alpha lipoic acid muaj qhov kev ua haujlwm siab, yog li cov ampoule yuav tsum tau muab tshem tawm hauv lub thawv tam sim ua ntej siv.
Lub txee lub neej ntawm cov tshuaj yog 3 xyoos.
Txoj kev lis ntshav tiav npaj yuav khaws cia rau hauv qhov chaw tsaus rau tsis ntau tshaj 6 teev.