Acekardol: cov lus qhia rau kev siv, tshuaj ntsuam xyuas thiab tshuaj xyuas, cov nqi hauv cov khw muag tshuaj ntawm Russia

Pom tau tsa tes yeeb ncuab MUSHROOM ntawm ntsia hlau! Koj cov ntsia hlau yuav raug ntxuav hauv 3 hnub! Coj nws.

Yuav ua li cas kom ceev cov leeg nrawm tom qab 40 xyoo? Daim ntawv qhia yooj yim, sau cia.

Nkees hemorrhoids? Muaj ib txoj kev tawm! Nws tuaj yeem raug kho nyob hauv tsev hauv ob peb hnub, koj xav tau.

Txog qhov muaj cov cab li hais tias ODOR los ntawm lub qhov ncauj! Ib zaug ib hnub, haus dej nrog ib tee ..

Sab sij huam

Raws li kev txheeb xyuas, Acecardol thiab nws cov analogue tuaj yeem ua rau cov kev mob tshwm sim hauv qab no:

• Hematopoietic system: ntshav khov, muaj feem yuav los ntshav,
• Kab mob ntsws: bronchospasm,
• Ua xua: urticaria, tawv nqaij ua pob khaus, khaus, Quincke's edema, kev mob plawv ntawm lub ntsws, o rau qhov ntswg ntawm lub qhov ntswg, anaphylactic ceeb,
• Lub hauv nruab nrab hauv lub paj hlwb: hnov ​​lus tsis zoo, ua haujlwm me me, kiv taub hau, mob taub hau Lub plab zom mov: mob plab, kub siab, xeev siab, ntuav, mob plab thiab ua rau mob plab duodenal, muaj kev ua haujlwm ntawm daim siab ua haujlwm siab.

Ib qho kev tshaj tawm tsis zoo li yuav tsis zoo, vim tias cov tshuaj nquag, acetylsalicylic acid, muaj nyob hauv ib qho me me. Kev siv tshuaj ntau dhau ntawm ASA tuaj yeem ua rau mob plab zom mov tau.

Cev xeeb tub thiab lactation

Cev xeeb tub thiab lactation yog lub ntsiab lus tseem ceeb rau kev siv tshuaj Acekardol. Tus neeg sawv cev siv tshuaj tiv thaiv yog raug txwv tsis pub dhau lub hlis 1 thiab 3 ntawm kev cev xeeb tub, hauv lub hlis thib ob kom ceev faj nrog kev ceev faj thiab tsuas yog tus kws kho mob hais kom ua. Nkag mus nyob rau lub sijhawm thib 2 lub tswv yim tsuas yog hais txog kev mob uas qhov txiaj ntsig ntawm kev kho mob rau leej niam ho dhau qhov kev hem thawj rau tus me nyuam hauv plab.

Cov Lus Cim Acekardol

Cov qauv ntawm cov qauv ua haujlwm:

• Tshuaj tua hluav taws,
• NUG-cardio,
• Aspicore
• Aspinat
• Aspirin York
• Tshuaj aspirin
• Tshuaj aspirin 1000,
• Aspirin Cardio,
• Aspirin Qhia Tawm,
• Acenterin,
• Acetylsalicylic acid
• Acylpyrine,
• Atsbirin,
• Npauj Npaim
• CardiASK,
• Cardiomagnyl
• Colpharite
• Mikristin
• Plidol 100,
• Plidol 300,
• Tus txhav yeeb,
• Taspir
• Thrombo ACC,
• Thrombogard 100,
• Thrombopol
• Walsh Asalgin,
• Upsarin UPSA,
• HSN Payne.

Xim: kev siv cov analogues yuav tsum pom zoo nrog tus kws kho mob koom.

Tus nqi nruab nrab ntawm ATSECARDOL, cov ntsiav tshuaj hauv cov khw muag tshuaj (Moscow) yog 25 rubles.

Tso tawm daim ntawv thiab muaj pes tsawg leeg

Acecardol yog tsim nyob rau hauv daim ntawv puag ncig biconvex ntsiav tshuaj, coated nrog lub plhaub dawb.

1 ntsiav tshuaj muaj:

• Cov khoom siv cuam tshuam: acetylsalicylic acid (ASA) - 50, 100 lossis 300 mg,
• Ntu cov khoom siv: lactose, titanium dioxide, magnesium stearate, roj taum castor, microcrystalline cellulose, povidone, pob kws nplej.

Sab sij huam

Cov kev qhia ceeb toom ceeb toom txog qhov ua tau ntawm kev txhim kho cov kev mob tshwm sim hauv qab no thaum muab tshuaj Acekardol:

• Ntawm ib feem ntawm cov txheej txheem ua pa: bronchospasm,
• Los ntawm sab nruab nrab ntawm lub hauv nruab nrab lub paj hlwb: tinnitus, hnov ​​lus tsis zoo, kiv taub hau, mob taub hau,
• Los ntawm cov kab mob hemopoietic: mob ntshav tsis txaus, muaj feem yuav los ntshav,
• Los ntawm lub plab zom mov: kub siab, ntuav, xeev siab, duodenal rwj, pais plab mucosa, lub plab zom mov tuaj, ua rau lub siab ua haujlwm tsis zoo,
• Kev tsis haum tshuaj: tawv nqaij ua pob khaus, tawm pob, urticaria, rhinitis, Quincke's edema, kev tsis nco qab uas tsis haum.

Cov Yuav Tsum Muaj

Acekardol yog contraindicated nyob rau hauv cov teeb meem hauv qab no:

• mob plawv tsis ua hauj lwm
• mob raum thiab siab mob tsis zoo,
• exacerbation ntawm erosive thiab ulcerative txhab ntawm lub gastrointestinal ib ntsuj av,
• hemorrhagic diathesis,
• mob hnyuv los ntshav,
• cov tshuaj tiv thaiv kab mob rau acetylsalicylic acid,
• bronchial hawb pob,
• lactase deficiency, qab zib-galactose malabsorption, lactose tsis haum,
• noj tshuaj methotrexate hauv ib lub lis piam 15 mg lossis ntau dua, thaum cev xeeb tub thiab lactation, hnub nyoog qis dua 18 xyoo.

Cob rau kev ceev faj thaum:

• raum tsis ua haujlwm thiab lub siab ua haujlwm,
• hyperuricemia, gout,
• keeb kwm mob rwj lub plab thiab lub rwj duodenal,
• cov kab mob ua pa ntev, mob qhov ntswg polyposis, quav nyab kub taub hau, ua xua,
• siv tshuaj tiv thaiv kev mob siab,
• noj cov tshuaj methotrexate hauv kev noj tshuaj ib lis piam tsawg dua 15 mg, hauv lub hlis thib ob ntawm cev xeeb tub thiab ua ntej thov kev phais mob (suav nrog cov me me).

Noj ntau dhau

Cov tsos mob ntau dhau muaj xws li kiv taub hau, xeev siab, mob taub hau, tsis meej pem, mob taub hau, tawm hws ntau heev, tachypnea, thiab hyperventilation.

Pom zoo kom lub plab zom mov, kev siv cov roj carbon tshuab txais hluav taws xob thiab rov ua dej-electrolyte sib npaug.

Nrog rau kev siv ntau tshaj, ua tau - lub cev kub heev, ua pa nyuaj, mob plawv, hlab ntshav hlwb, ntshav qabzib cov ntshav, ntshav tawm hauv lub plab thiab cov hnyuv.

Hauv qhov no, maj mam pw hauv tsev kho mob thiab kho kev kub ntxhov, suav nrog kev ntxuav lub plab zom mov, rov qab siv cov pa roj carbon activated, hemodialysis, yuam alkaline diuresis, kho kom rov qab ua haujlwm ntawm acid-base xeev thiab dej-electrolyte tshuav nyiaj, nrog rau kev teem sijhawm kho mob kom zoo rau kev tshem tawm cov tsim kev ua txhaum.

Cov lus qhia tshwj xeeb

Acekardol tuaj yeem ua rau mob ntsws mob ntsws thiab mob ntsws asthma. Cov muaj feem muaj mob: keeb kwm ntawm qhov ntswg polyposis, quav nyab kub taub hau, phiv tshuaj, mob ntsws asthma.

Qhov ua tiav ntawm kev cuam tshuam los ntawm kev ua kom cov ntshav platelet txuas ntxiv tau ntev mus ob peb hnub, uas tuaj yeem ua rau ntshav los ntshav thaum kev phais mob thaum muaj xwm ceev. Ua ntej txoj haujlwm tau teem tseg, cov tshuaj tau raug muab tso tseg tsawg kawg 7 hnub ua ntej.

Hauv cov neeg mob uas ntxim nyiam, Acecardol hauv kev txhaj tshuaj me me tuaj yeem ua rau mob gout. Ntawm kev pheej hmoo yog cov uas txo qis uric acid excretion.

Nrog rau qhov nce ntxiv ntawm cov tshuaj, cov kev pheej hmoo ntawm los ntshav ntawm lub plab zom mov nce ntau.

Nws tsis muaj kev cuam tshuam nrog lub peev xwm ntawm kev tsav tsheb. Hauv kev kho mob ntawm glucocorticosteroids, nws yuav tsum tau yug los hauv lub siab tias nrog lawv tshem tawm txoj cai, kev noj ntau dhau ntawm salicylates yog ua tau.

Kev sib txuam

Acecardol ua kom muaj zog nce lub tshuaj lom ntawm methotrexate, txo nws lub raum kev tshem tawm, valproic acid. Txhim kho qhov cuam tshuam ntawm lwm cov NSAIDs, tshuaj yeeb tshuaj analgesics, tshuaj tiv thaiv hypoglycemic hauv qhov ncauj, heparin, indirect anticoagulants, thrombolytics thiab antiplatelet agents, sulfonamides (suav nrog co-trimoxazole), T3. Txo cov nyhuv ntawm cov tshuaj uricosuric (benzbromarone, sulfinpyrazone), cov tshuaj tiv thaiv kab mob, diuretics (spironolactone, furosemide).

GCS, ethanol thiab ethanol-muaj cov tshuaj ua rau muaj kev puas tsuaj tshwm sim ntawm lub plab hnyuv, ua rau muaj kev pheej hmoo hauv cov hnyuv ntshav.

Tsub kom cov concentration ntawm digoxin, barbiturates, thiab Li + ntsev rau hauv ntshav.

Cov tshuaj tiv thaiv kab mob muaj Mg2 + thiab / lossis Al3 + qeeb thiab ua rau cov teeb meem tsis haum ntawm ASA.

Myelotoxic tshuaj ntxiv rau qhov ua kom pom qhov hematotoxicity ntawm cov tshuaj.

Acecardol, cov lus qhia rau kev siv (Txoj kev thiab ntau npaum li cas)

Cov tshuaj yog pom zoo kom noj ua ntej noj mov. Nws raug nquahu kom haus cov ntsiav tshuaj nrog qhov muaj kua txaus. Cov tshuaj tau kho rau lub sijhawm ntev. Tshaj tawm ntawm kev pub nkag - 1 zaug nyob rau ib hnub.

Yog tias mob myocardial infarction yog xav tias yuav tiv thaiv teem 100 mg txhua txhua hnub lossis 300 mg rau txhua lwm hnub. Cov tshuaj txhuam hniav muab cov nyhuv sai dua, uas yog qhov tseem ceeb hauv thawj cov sijhawm ntawm myocardial infarction. Yog tias muaj ntau yam kev pheej hmoo ib zaug, 300 mg txhua txhua lwm hnub, lossis 100 mg txhua hnub, tau raug tshaj tawm rau kev tiv thaiv kab mob siab myocardial infarction.

Kev tiv thaiv ntawm tsis khov kho lub hlwb angina pectoris, rov ua dua lub plawv nres, tiv thaiv kev hloov kab mob cerebrovascular, ischemic mob stroke: 100-300 mg txhua hnub.

Rau kev tiv thaiv ntawm pulmonary embolism, sib sib zog nqus hlab ntsha thrombosis teem 300 mg rau txhua lwm hnub, lossis 100 mg txhua hnub.

Noj ntau dhau

Cov tsos mob me me xws li kiv taub hau, xeev siab, mob taub hau, tsis meej pem, mob taub hau, tawm hws ntau dhau, tachypnea, thiab hyperventilation yog ua tau. Hauv qhov no, txoj kev kho yuav koom nrog kev mob plab, kev noj cov roj carbon ntau, thiab rov qab kho cov dej-electrolyte tshuav nyiaj li cas.

Nrog rau kev mob hnyav dhau ntawm kev siv ntau dhau, ua tau: lub cev kub heev, ua pa nyuaj, hlab plawv, cov hlab ntsha hlwb, ntshav qabzib cov ntshav, los ntshav hauv lub plab thiab cov hnyuv. Thiab hauv qhov no yuav tau pw hauv tsev kho mob ceev ceev.

Cov Tshuaj Pharmacokinetics

Tom qab kev tswj hwm ntawm qhov ncauj, ASA tau nrawm thiab nrawm los ntawm txoj hnyuv, lub sijhawm ntawd nws nrog qee qhov khoom noj. Thaum lub sijhawm thiab tom qab nqus, ASA hloov mus rau hauv qhov tseem ceeb metabolite - salicylic acid, uas yog metabolized feem ntau hauv daim siab (nyob rau hauv kev cuam tshuam ntawm enzymes) los tsim cov metabolites xws li salicylic acid, salicylic acid glucuronide thiab phenyl salicylate. Lawv muaj nyob hauv ntau cov ntaub so ntswg thiab zis. Rau cov poj niam, cov txheej txheem metabolic qeeb dua li txiv neej.

Tom qab noj Acecardol sab hauv, qhov siab tshaj plaws ntawm ASA hauv cov ntshav ntshav yog pom tom qab 10-20 feeb, salicylic acid - tom qab 0.3-2 teev.

Cov ntsiav tshuaj Acecardol yog coated nrog cov tshuaj tiv thaiv acid-tiv thaiv, uas tiv thaiv cov tshuaj los ntawm kev ua kom lub plab zom mov, yog li cov tshuaj nquag tso tawm hauv alkaline ib puag ncig ntawm duodenum. Hauv qhov no, qhov nqus ntawm ASA yog 3-6 teev qeeb dua li thaum noj cov ntsiav tshuaj (tsis muaj coated nrog lub plhaub).

Acetylsalicylic thiab salicylic acids khi rau cov ntshav plasma protein (nyob ntawm qhov koob tshuaj, qhov ntsuas no yog 66–98%) thiab tau faib sai sai hauv lub cev. Salicylic acid kis tau los ntawm cov hno mis thiab mus rau hauv niam cov kua mis.

Kev siv cov metabolism ntawm salicylic acid yog txwv los ntawm kev muaj peev xwm ntawm cov txheej txheem enzymatic, yog li ntawd, nws qhov kev nthuav tawm yog koob tshuaj.Ib nrab-lub neej kav ntev txog 2-3 teev (nyob rau hauv cov koob tshuaj qis) mus rau 15 teev (thaum siv cov koob tshuaj loj ua ib qho tshuaj tiv thaiv kab mob thiab ua kom loog).

Nrog rau siv ntev, non-hydrolyzed ASA tsis ntau ntau hauv cov ntshav cov ntshav, tsis zoo li lwm yam salicylates.

Salicylic acid thiab nws cov metabolites yog ua tawm los ntawm lub raum. Nrog rau lub raum kev ua haujlwm, txij li 80 txog 100% ntawm ib zaug ntawm ASA raug tso tawm nyob rau hauv 24-7 teev.

Tsuas tshuaj thiab tswj hwm

Acecardol ntsiav tshuaj noj ntawm qhov ncauj ua ntej noj mov, ntxuav nrog dej. Cov tshuaj yog npaj rau kev siv sijhawm ntev.

Yog tias xav tias myocardial infarction, Acecardol tau noj 100 mg ib zaug ib hnub lossis 300 mg txhua lwm hnub. Rau qhov pom kev kho kom zoo tshaj plaws, thawj ntsiav tshuaj yuav zom.

Txhawm rau tiv thaiv kom tsis txhob mob myocardial infarction, txhaws ntawm cov hlab ntsws thiab nws cov ceg nrog ntshav txhaws, nqus ntshav ntawm cov leeg ntshav thiab nrog lub plawv tsis khov, Acecardol noj 100-300 mg ib hnub.

Txhawm rau tiv thaiv thromboembolism tom qab kev tawm tsam thiab kev phais mob, kev noj tshuaj ntawm Acecardol yog 100-300 mg txhua hnub.

Cev xeeb tub thiab lactation

Hauv thawj peb lub hlis thaum cev xeeb tub, salicylates nyob rau hauv cov koob tshuaj loj ua rau muaj kev pheej hmoo ntawm tsim muaj cov tsis xws luag hauv plab (cais tawm ntawm lub plab, lub plawv tsis zoo), yog li ntawd Acecardol yog nruj me ntsis contraindicated rau kev siv.

Hauv ob lub hlis thib ob ntawm kev xeeb tub, cov tshuaj tuaj yeem tsuas yog tsim nyog yog tias cov txiaj ntsig tau pom zoo yog qhov muaj txiaj ntsig tshwj xeeb tshaj qhov kev pheej hmoo. Nyob rau tib lub sijhawm, nws raug nquahu kom siv Acecardol nyob rau hauv cov koob tshuaj tsis ntau tshaj 150 mg rau cov kev kawm luv tshaj.

Hauv lub hlis thib peb ntawm cev xeeb tub, salicylates hauv kev txhaj tshuaj ntau dua (ntau dua 300 mg / hnub) ua rau lub zog tsis muaj zog, ua rau muaj ntshav ntau ntxiv rau leej niam thiab tus menyuam hauv plab, thiab lub sijhawm ntxov ua haujlwm ntawm tus mob ductus arteriosus hauv cov menyuam hauv plab. Noj tshuaj ASA ua ntej yug tau tuaj yeem ua rau mob ntshav liab, tshwj xeeb tshaj yog cov menyuam yaus ua ntej. Hauv qhov no, hauv lub caij nyoog dhau los ntawm cev xeeb tub, Acecardol yog nruj me ntsis contraindicated rau kev siv.

Salicylates thiab lawv cov metabolites kis tau rau hauv niam cov kua mis, uas yog vim li cas Acecardol yog contraindicated rau cov poj niam uas pub niam mis. Yog tias noj cov tshuaj muaj yees zoo, koj yuav tsum tsis txhob pub mis niam.

Yeeb tshuaj sib cuam tshuam

Thaum muaj kev sib txig, siv cov tshuaj acetylsalicylic acid ua rau tsis muaj zog ntawm cov tshuaj hauv qab no: diuretics, angiotensin-hloov enzyme inhibitors (ACE), tshuaj uricosuric (benzbromarone).

Kev siv thaum tib lub sijhawm, acetylsalicylic acid ua rau kev ua ntawm cov tshuaj hauv qab no: cov tshuaj tiv thaiv kab mob thiab cov tshuaj thrombolytic, digoxin, heparin thiab tsis siv tshuaj anticoagulants, methotrexate, valproic acid, hypoglycemic tshuaj (insulin thiab sulfonylurea derivatives).

Tsis tas li, kev sib xyaw ntawm ASA nrog methotrexate yog txuam nrog kev pheej hmoo ntawm kev phiv tshuaj los ntawm hemopoietic plab hnyuv siab raum, nrog thrombolytics, tshuaj antiplatelet thiab anticoagulants - kev pheej hmoo ntawm los ntshav.

ASA txhim kho kev lom rau cov tshuaj lom los ntawm ethanol nyob rau hauv nruab nrab lub paj hlwb. Qhov no ua rau muaj kev puas tsuaj ntxiv rau cov qog ua pa ntawm lub plab thiab txoj hlab ntaws ntev.

Systemic glucocorticosteroids txhim kho txoj kev tshem tawm ntawm cov tshuaj, dua li nws cov nyhuv tsis muaj zog.

Cov qauv ua haujlwm ntawm cov qauv Acecardol yog qhov npaj Thrombo ACC, Aspirin, Cardiopyrine, Aspinate, Aspicor, Taspir, Thrombopol, Acetylsalicylic acid.

Kev txheeb xyuas txog Acecardol

Raws li kev tshuaj xyuas, Acekardol yog ib qho kev tiv thaiv kab mob antiplatelet zoo uas ua kom ntshav thiab tiv thaiv kom tsis txhob mob thrombosis. Nws cov txiaj ntsig ntxiv muaj xws li tus nqi qis (piv rau feem ntau cov yeeb yaj kiab), kev yooj yim ntawm kev tswj hwm (1 zaug hauv ib hnub), daim ntawv tshuaj (cov txheej txheem nkag tau tiv thaiv lub plab los ntawm cov teeb meem ntawm acetylsalicylic acid), nrog rau muaj ntau cov tshuaj ntawm cov ntsiav tshuaj (50, 100 thiab 300 mg), uas tso cai rau koj xaiv qhov kev xaiv zoo tshaj plaws.

Qhov tsis zoo ntawm Acecardol suav nrog cov tsis muaj contraindications. Txawm li cas los xij, lawv muaj rau txhua tus salicylates, yog li tus kws kho mob yuav tsum muab tshuaj rau kev kho.