Cov tshuaj Pentoxifylline 100: cov lus qhia rau kev siv
Pentoxifylline 100 yog cov tshuaj siv rau hauv kev kho mob ntawm cov kab mob nrog los ntawm cov ntshav ntau ntxiv. Nws muaj contraindications thiab phiv, yog li ntawd nws yog kws kho tom qab kawm cov kev soj ntsuam los ntawm kev tsom xam.
Tso tawm daim ntawv thiab muaj pes tsawg leeg
Cov tshuaj yuav zoo li:
- Kev daws rau kev tswj hwm ntawm intravenous thiab intraarterial. 1 ml muaj 0.1 g ntawm pentoxifylline, sodium tshuaj dawb tov, monovalent sodium phosphate, dej rau kev txhaj tshuaj. Cov tshuaj muaj daim ntawv tsis muaj xim tsis muaj kua uas tau hliv rau hauv 5 ml iav ampoules. Cov thawv ntim khoom muaj 10 ampoules thiab cov lus qhia.
- Cov ntsiav tshuaj yog coated nrog zaj duab xis liab soluble. Txhua tus muaj 100 mg ntawm pentoxifylline, stearic acid, povidone, pob kws nplej siab, mis qab zib, cellulose hmoov, cellacephate, titanium dioxide, castor roj, kua paraffin, talc, beeswax. Cov pob muaj xws li 10, 30, 50 lossis 60 ntsiav tshuaj.
Pharmacological kev txiav txim siab ntawm Pentoxifylline 100
Pentoxifylline muaj cov khoom hauv qab no:
- normalizes peripheral vascular ncig,
- txhim kho rheological zog ntawm cov ntshav,
- inhibits phosphodiesterase, nce qib ntawm adenosine monophosphate hauv platelets thiab adenosine triphosphate hauv cov ntshav liab,
- ua kom ntau ntxiv ntawm lub zog tso tawm los ntawm cov qe ntshav, uas pab txhawb kev nthuav dav ntawm cov hlab ntshav,
- txo peripheral vascular tsis kam,
- tsub kom cov txiaj ntsig rau lub plawv yam tsis cuam tshuam rau lub plawv dhia,
- nce qhov khoob ntawm cov hlab ntsha loj, muab cov pa oxygen rau cov leeg plawv,
- nthuav tawm cov hlab ntsws, ua kom ntshav muaj pa oxygen,
- nce cov ntshav ntws los ntawm hla kev hla ntawm lub nkoj,
- tshem tawm cov kab mob ntshav viscosity, tiv thaiv platelet adhesion, nce cov ntshav liab ua kom lub cev txav taus,
- txhim kho cov ntshav muab rau cov nqaij ischemic,
- tshem tawm kev ua pob ntawm lub plab hlaub nqaij uas cuam tshuam nrog kev cuam tshuam ntawm cov hlab ntshav ntawm qhov qis qis.
Nrog kev tswj hwm ntawm qhov ncauj thiab niam txiv, pentoxifylline nkag mus rau hauv lub siab, qhov chaw nws hloov pauv mus ua 2 metabolites nrog cov khoom zoo ib yam li cov khoom ntawm cov pib. Qhov siab tshaj plaws ntawm cov tshuaj hauv cov ntshav tau txiav txim siab tom qab 90-120 feeb. Qhov kev tshem tawm ib nrab-lub neej kav 3 teev. Feem ntau cov tshuaj nquag tso tawm los ntawm lub raum, qhov seem ntawm pentoxifylline tawm hauv lub cev nrog zis.
Kev Qhia Tawm Pentoxifylline 100
Cov npe ntawm cov cim qhia rau kev qhia ntawm cov tshuaj muaj xws li:
- circulatory ntshawv siab cuam tshuam nrog atherosclerotic lossis ntshav qab zib qhov txhab ntawm peripheral hlab ntsha,
- ischemic txhab qhov txhab ntawm cov nqaij mos,
- encephalopathies cuam tshuam nrog atherosclerosis ntawm cerebral cov hlab ntsha thiab cov mob hlwb cerebrovascular,
- Raynaud's syndrome
- cov nqaij hauv lub cev tsis muaj teeb meem cuam tshuam nrog kev ua txhaum ntawm lub luag haujlwm ntawm cov hlab plawv hlab ntsws (trophic ulcers, frostbite, gangrene, mob post-thrombophlebitis),
- obliterating endarteritis,
- circulatory mob nyob rau hauv cov hlab ntsha ntawm lub txhab nyiaj thiab cov roj ntsha ntawm lub qhov muag
- hnov lus tsis zoo vim muaj teeb meem vascular.
Yuav noj li cas
Txoj kev siv nyob ntawm daim ntawv tshuaj
- Cov ntsiav tshuaj tau noj tom qab noj mov. Lawv nqos tsis tau zom, thiab ntxuav nrog qhov uas muaj dej txaus. Qhov pom zoo kom noj txhua hnub yog 600 mg. Nws muab faib ua 3 koob. Tom qab kev txhim kho, qhov koob tshuaj yog txo kom txij nkawm (300 mg ib hnub). Lub chav kawm ntawm kev kho mob kav 7-14 hnub. Qhov koob tshuaj txhua hnub yuav tsum tsis pub tshaj 12 ntsiav tshuaj.
- Kev daws rau Txoj kev lis ntshav. Thaum lub sij hawm tus txheej txheem, tus neeg mob yuav tsum nyob rau hauv txoj hauj lwm supine. Kev daws yog muab kua nrog maj mam. Ua ntej siv, cov ntsiab lus ntawm ampoule tau pauv mus rau hauv ib lub hnab nrog 250-500 ml ntawm kua ntsev los yog dextrose tov. 300 mg ntawm pentoxifylline yog muab rau ib hnub. Nrog kev siv hauv txoj leeg ntshav, 5 ml ntawm cov tshuaj tau muab sib xyaw nrog 20-50 ml ntawm cov tshuaj isotonic. Thaum cov hlab ntsha hlwb dhau mus lawm, pentoxifylline tsis tuaj yeem raug txhaj rau hauv cov leeg carotid.
Qhov tshwm sim phiv ntawm Pentoxifylline 100
Thaum siv Pentoxifylline, koj yuav ntsib kev:
- cov leeg mob (qhov mob ntawm thaj chaw ntawm sab xub ntiag thiab sab nqaij daim tawv, kiv taub hau, ntxhov siab ntxhov siab, hmo ntuj tsis tsaug zog thiab nruab hnub pw tsaug zog, mob huam)
- cov cim qhia ntawm kev puas tsuaj rau cov tawv nqaij thiab cov nqaij mos (liab ntawm daim tawv nqaij, kub ntxig mus rau lub ntsej muag thiab lub hauv siab, o ntawm cov nqaij mos subcutaneous, muaj qhov tsis zoo ntawm cov ntsia hlau),
- ua txhaum ntawm lub luag haujlwm ntawm lub plab zom mov (tsis muaj qab los noj mov, lub plab hnyuv tsis tuaj yeem, mob rau lub plab hauv plab, ua kom lub siab ua haujlwm)
- txo hauv kev pom tseeb, scotoma,
- hlab plawv pathologies (mob plawv atherosclerosis disturbances, mob hauv lub plawv, nce zaus ntawm kev tawm tsam angina, hlab ntsha hypotension),
- kev cuam tshuam los ntawm cov ntshav hematopoietic (txo qis ntawm cov platelets thiab leukocytes, nce prothrombin lub sijhawm, los ntshav ntawm cov pos hniav thiab cov qog ua pa, plab hnyuv, mob rau qhov ntswg thiab lub cev).
- cov kab mob ua xua (liab thiab khaus ntawm daim tawv nqaij, tawm pob zoo li khaus, o ntawm lub ntsej muag thiab lub ntsej muag, qhov tshuaj tiv thaiv anaphylactoid),
- nce kev ua si ntawm daim siab enzymes thiab alkaline phosphatase.