Cov lus qhia rau kev siv tshuaj, tshuaj yeeb dawb, tshuaj xyuas

Lyspro insulin yog ib qho tshuaj ntawm tib neeg cov tshuaj insulin. Lyspro insulin txawv ntawm tib neeg insulin hauv kev rov qab ntawm cov kab sib txuas thiab lysine amino acid seem ntawm txoj haujlwm 28 thiab 29 ntawm cov kab insulin B. Lyspro insulin tswj cov metabolism hauv qabzib. Tsis tas li, insulin lyspro muaj cov teebmeem ntawm kev tiv thaiv catabolic thiab anabolic rau ntau cov ntaub so ntswg ntawm lub cev. Hauv cov leeg nqaij, cov ntsiab lus ntawm glycogen, fatty acids, glycerol nce, muaj kev noj cov amino acid thiab nce synthesis protein ntau, tab sis qhov no txo qis gluconeogenesis, glycogenolysis, lipolysis, ketogenesis, protein catabolism thiab tso cov amino acids. Lyspro insulin tau pom tias yog ua kom sib npaug rau tib neeg cov tshuaj insulin. Thaum piv nrog luv luv ua yeeb yam insulin npaj, lispro insulin yog tus cwj pwm los ntawm kev pib sai dua thiab qhov kawg ntawm cov nyhuv. Qhov no yog vim muaj qhov nqus tau ntxiv los ntawm cov subcutaneous depot vim yog kev txuag ntawm monomeric qauv ntawm lyspro insulin lwg me me hauv cov tshuaj. 15 feeb tom qab kev tswj hwm subcutaneous, cov nyhuv ntawm insulin lispro tau pom, cov nyhuv siab tshaj plaws tau pom ntawm 0.5 thiab 2.5 teev, lub sijhawm ua ntawm 3-4 teev. Hauv cov neeg mob uas muaj hom 1 thiab hom 2 mob ntshav qab zib mellitus, hyperglycemia, uas tshwm sim tom qab noj mov, poob qis dua thaum siv lyspro insulin thaum piv nrog soluble tib neeg cov kua dej. Rau cov neeg mob uas tau txais cov qis qis thiab ua yeeb yaj kiab luv luv, koob tshuaj ntawm ob qho tshuaj yuav tsum raug xaiv thiaj li ua tiav cov ntshav qabzib hauv lub hnub thawm hnub. Lub sijhawm ntawm cov kev ua ntawm insulin lispro, raws li rau txhua txoj kev npaj tshuaj insulin, tuaj yeem sib txawv hauv cov neeg mob lossis sijhawm sib txawv ntawm cov tib neeg thiab nyob ntawm lub koob tshuaj, kev muab ntshav, qhov chaw txhaj tshuaj, kev tawm dag zog thiab lub cev kub. Cov chaw muag tshuaj ntawm cov kua dej lyspro hauv cov menyuam yaus zoo ib yam li tau pom hauv cov neeg laus. Hauv cov neeg mob uas muaj ntshav qab zib hom 2 uas tau txais ntau tshaj plaws ntawm sulfonylurea derivatives, qhov sib ntxiv ntawm lyspro insulin ua rau txo qis glycosylated hemoglobin hauv pawg ntawm cov neeg mob no. Lyspro insulin txoj kev kho rau cov neeg mob uas muaj hom 1 thiab ntshav qab zib hom 2 yog nrog nws cov neeg tsawg zuj zus mus ntawm nocturnal hypoglycemia. Glucodynamic teb rau lyspro insulin yog ywj siab ntawm daim siab los yog lub raum ua haujlwm.
Thaum muab tshuaj subcutaneously, lyspro cov tshuaj insulin yog nqus sai thiab nce mus txog qhov siab tshaj plaws hauv cov ntshav tom qab 30 - 70 feeb. Qhov ntim ntawm kev faib tawm ntawm cov tshuaj insulin lispro yog 0.26 - 0.36 l / kg thiab zoo tib yam rau qhov ntim ntawm kev faib tawm ntawm tib neeg cov insulin. Ib nrab-lub neej ntawm insulin lyspro nrog subcutaneous saib xyuas yog kwv yees li 1 teev. Hauv cov neeg mob uas tsis zoo lub cev ua haujlwm ntawm lub siab thiab / lossis ob lub raum, qhov siab dua ntawm kev nqus ntawm lispro insulin tseem yog thaum piv nrog cov tshuaj insulin tib neeg.

Hom 1 mob ntshav qab zib mellitus (insulin-dependant), xav tau cov tshuaj insulin los kho cov ntshav qabzib hauv lub siab, suav nrog kev tsis haum rau lwm yam tshuaj insulin, kev tiv thaiv insulin tsis txaus (ua kom tsis muaj zog hauv zos insulin), postprandial hyperglycemia, uas tsis tuaj yeem kho los ntawm lwm cov tshuaj insulin.
Hom 2 mob ntshav qab zib mellitus (non-insulin-dependant), xav tau cov tshuaj insulin los tswj cov ntshav qabzib hauv lub cev: nrog kev nqus tsis tau ntawm lwm yam tshuaj insulin, kev tiv thaiv kab mob hauv lub qhov ncauj, tsis raug kho tom qab lub zog hyperglycemia, nrog cov kabmob sib kis, kev khiav haujlwm.

Lyspro insulin tswj hwm thiab ntau npaum li cas

Lyspro insulin yog muab tshuaj subcutaneously, intramuscularly thiab mob leeg 5 mus rau 15 feeb ua ntej noj mov. Qhov ntau npaum cov tshuaj thiab txoj kev ntawm cov thawj coj tau teeb tsa ua ib tus zuj zus.
Lyspro insulin tuaj yeem siv ua ntej ua ntej noj mov. Yog tias tsim nyog, Lyspro insulin tuaj yeem muab sijhawm sai tom qab noj mov.
Tus neeg mob yuav tsum tau kawm siv cov txheej txheem kev txhaj tshuaj kom raug. Subcutaneously yuav tsum tau txhaj rau hauv tus ncej puab, xub pwg, plab lossis pob tw. Qhov chaw txhaj tshuaj yuav tsum tau hloov chaw kom tib qhov chaw siv tsis ntau tshaj ib hlis ib zaug. Nrog kev tswj hwm subcutaneous ntawm insulin lyspro, kev saib xyuas yuav tsum tau saib xyuas kom tsis txhob txais cov tshuaj rau hauv cov hlab ntshav. Tom qab txhaj tshuaj, qhov chaw txhaj tshuaj yuav tsum tsis txhob zaws.
Yog tias tsim nyog (mob hnyav, ketoacidosis, lub sijhawm ntawm kev ua haujlwm lossis sijhawm ua haujlwm tom qab), lisproin insulin tuaj yeem muab tshuaj rau hauv cov leeg ntshav.
Nws yog ib qho tsim nyog yuav tsum tau soj ntsuam nruj ntawm txoj hauv kev ntawm kev tswj hwm, uas yog npaj rau kev siv ntau npaum ntawm cov tshuaj insulin lispro.
Koob tshuaj yuav tau kho thaum hloov mus rau cov neeg mob rau lyspro insulin nrog kev siv tshuaj insulin npaj sai ntawm cov tsiaj keeb kwm. Cov kev hloov pauv hauv cov kev ua, hom (tus tsim khoom), hom, hom, hom ntawm kev tsim cov tshuaj insulin tuaj yeem ua rau qhov kev xav tau ntawm kev hloov koob tshuaj. Kev hloov chaw ntawm cov neeg mob los ntawm ib hom tshuaj insulin mus rau lwm qhov yuav tsum tau ua nyob rau hauv kev saib xyuas mob nkeeg nruj me ntsis, thiab cov neeg mob uas tau txais insulin hauv ib hnub ntau dua 100 chav nyob hauv tsev kho mob.
Nrog rau kev mob siab, thaum kis cov kab mob, thaum ntxiv kev noj tshuaj nrog rau hyperglycemic kev ua si (glucocorticoids, cov thyroid hormones, thiazide diuretics, tshuaj tiv thaiv hauv qhov ncauj), nrog rau kev nce hauv carbohydrates hauv zaub mov, qhov kev xav tau rau insulin yuav nce.
Qhov xav tau rau cov insulin tuaj yeem txo nrog qhov txo qis hauv carbohydrates hauv cov zaub mov, daim siab thiab / lossis lub raum tsis ua haujlwm (vim tias txo qis gluconeogenesis thiab insulin metabolism), kev ua haujlwm hauv lub cev ntau ntxiv, siv cov tshuaj ntxiv nrog cov kev ua haujlwm hypoglycemic (tsis xaiv beta-blockers, monoamine oxidase inhibitors, sulfonamides). Tab sis hauv cov neeg mob mob siab tsis ua hauj lwm ntev, muaj peev xwm tiv thaiv insulin ntau dua tuaj yeem ua rau muaj kev nce siab ntxiv ntawm insulin.
Cov kev mob uas cov cim qhia ntxov ntawm hypoglycemia tej zaum yuav tsis tshua tau hais thiab tsis paub meej suav nrog kev kho mob ntau ntxiv nrog insulin, txuas ntxiv cov ntshav qab zib mellitus, kab mob ntawm cov hlab ntsha hauv ntshav qab zib mellitus, thiab siv cov tshuaj, xws li beta-blockers.
Hauv cov neeg mob hypoglycemia, tom qab hloov chaw los ntawm tsiaj cov tshuaj insulin rau tib neeg cov tshuaj insulin, cov tsos mob thaum ntxov ntawm hypoglycemia yuav tsis tshua tshaj li cov neeg tau ntsib nrog lawv txoj kev kho insulin yav dhau los. Cov kev tsis pom zoo hyperglycemic lossis hypoglycemic tshua tuaj yeem ua rau tsis nco qab, rau leej twg, tuag.
Kev siv cov koob tshuaj tsis txaus los sis tsis txiav kev kho mob, tshwj xeeb tshaj yog rau cov neeg mob ntshav qab zib hom 1 tuaj yeem ua rau hyperglycemia thiab ntshav qab zib ketoacidosis, uas muaj feem yuav ua rau tuag tau rau tus neeg mob.
Koob tshuaj yuav tau noj yog hais tias tus neeg mob ib txwm noj mov hloov lossis ua si lub cev ntau ntxiv. Kev tawm dag zog tam sim ntawd tom qab noj mov tuaj yeem nce qhov kev pheej hmoo ntawm lub qog ntshav qab zib.
Thaum siv cov tshuaj insulin ua ke nrog cov tshuaj ntawm thiazolidinedione pab pawg, qhov kev pheej hmoo ntawm kev txhim kho edema thiab mob plawv tsis ua haujlwm nce, tshwj xeeb tshaj yog nyob rau cov neeg mob uas muaj kab mob ntawm cov hlab plawv thiab muaj cov kev pheej hmoo ua rau mob plawv tsis ua haujlwm.
Kev nrawm ntawm cov tshuaj tiv thaiv thiab tus neeg mob lub peev xwm mloog zoo tuaj yeem ua rau hyperglycemia lossis hypoglycemia, uas cuam tshuam nrog kev noj tshuaj tsis raug cai ntawm insulin lispro, uas tuaj yeem ua rau muaj xwm txheej nyob rau hauv cov xwm txheej uas cov peev xwm no muaj qhov tseem ceeb (piv txwv, ua haujlwm nrog kev siv tshuab, tsav tsheb thiab lwm tus). Cov neeg mob yuav tsum tau ceev faj kom tsis txhob mob ntshav qab zib thaum tsav tsheb lossis ua haujlwm uas qhov chaw nce siab thiab ceev ntawm lub hlwb kev xav tau. Qhov no tseem ceeb tshwj xeeb tshaj yog rau cov neeg mob uas tsis muaj lossis tsis tshua hnov qab los ntawm kev mob tshwm sim ntawm kev ua qog ntshav lossis ua rau leej twg muaj ntshav tsis txaus yog feem ntau pom. Hauv cov xwm txheej no, qhov tsim nyog ntawm kev ua cov haujlwm uas yuav tsum muaj kev saib xyuas ntau ntxiv thiab ceev ntawm lub hlwb kev xav, suav nrog kev tsav tsheb, yuav tsum raug ntsuas.
Cov Yuav Tsum Muaj
Kev ua haujlwm tsis txaus siab, kev ua ntshav qab zib.

Cev xeeb tub thiab lactation

Nyob rau lub sijhawm tam sim no, tsis muaj qhov tsis xav tau ntawm Lyspro insulin rau kev xeeb tub lossis rau kev noj qab haus huv ntawm tus menyuam hauv plab thiab cov menyuam tshiab tau pom. Cov kev tshawb fawb cuam tshuam txog kev sib kis thoob plaws niaj hnub no tsis tau ua. Thaum cev xeeb tub, qhov tseem ceeb yog tswj cov glycemic zoo hauv cov neeg mob ntshav qab zib uas tau txais kev kho mob insulin. Qhov kev xav tau rau insulin thaum cev xeeb tub feem ntau poob rau thawj peb hlis thiab nce hauv qib thib ob thiab thib peb. Qhov xav tau rau insulin tuaj yeem txo qis heev thaum yug menyuam thiab tam sim ntawd. Cov neeg mob ntshav qab zib yuav tsum sab laj nrog kws kho mob yog tias lawv xeeb tub los yog npaj ua cev xeeb tub. Thaum cev xeeb tub hauv cov poj niam muaj ntshav qab zib, qhov tseem ceeb yog ua tib zoo saib xyuas cov piam thaj thiab kev noj qab haus huv txhua yam. Tsis paub meej tias cov lyspro insulin kis mus rau leej niam mis ntau npaum li cas. Hauv cov neeg mob uas mob ntshav qab zib mellitus thaum pub niam mis, yuav tsum tau txhaj tshuaj insulin thiab / lossis noj zaub mov kom haum.

Phiv los ntawm insulin lyspro

Kev mob ntshav qab zib (nce hws, pallor, palpitations, pw tsaug zog, tshee tshee, mob puas hlwb), mob ntshav qab zib ua ntej thiab coma (suav txog qhov txiaj ntsig tuag), kev hloov pauv hloov pauv tsis raug, kev tsis haum (hauv zos - liab, o, khaus ntawm qhov chaw txhaj tshuaj, dav dav - urticaria, khaus thoob plaws lub cev, angioedema, ua tsis taus pa, kub taub hau, txo cov ntshav siab, tawm hws, tachycardia), lipodystrophy, edema.

Kev cuam tshuam ntawm cov tshuaj insulin lispro nrog lwm yam tshuaj yeeb dej caw

Amprenavir, betamethasone, hydrocortisone, hydrochlorothiazide, glucocorticosteroids, danazole, diazoxide, dexamethasone, isoniazid, nicotinic acid, salbutamol, terbutaline, rhytodrin, cov tshuaj tiv thaiv kab mob hauv lub qhov ncauj, cov tshuaj tiv thaiv thyroid antipyretic, thiazide antipyret ua kom tsis muaj zog ntawm cov tshuaj insulin lyspro, nws yog qhov ua tau ntawm kev loj hlob ntawm hyperglycemia, ib qho kev nce ntawm koob tshuaj insulin lispro.
Acetylsalicylic acid, bisoprolol, sulfanilamide tshuaj tua kab mob, captopril, qee cov tshuaj tiv thaiv kab mob (monoamine oxidase inhibitors), beta-blockers, octreotide, phenfluramine, enalapril, acarbose, anabolic steroids, tetracyclines, guanorotin agenitrogen inhibitors, tshuaj noj , ethanol thiab ethanol-muaj cov tshuaj txhim kho cov nyhuv ntawm insulin lispro.
Diclofenac hloov cov nyhuv ntawm insulin lispro, tswj ntshav qabzib yog tsim nyog.
Thaum siv ua ke nrog cov tshuaj insulin, lyspro beta-blockers, clonidine, reserpine, bisoprolol tuaj yeem zais qhov tshwm sim ntawm cov tsos mob ntawm kev ua qog ntshav qab zib.
Lyspro insulin yuav tsum tsis txhob xyaw nrog tsiaj tshuaj insulin.
Ntawm kev pom zoo los ntawm tus kws kho mob, Lyspro insulin tuaj yeem siv nrog kev ua haujlwm ntev ntawm tib neeg cov kua dej lossis nrog cov ncauj lus sulfonylurea npaj.
Thaum siv lwm yam tshuaj nrog lyspro insulin, sab laj koj tus kws kho mob.

Noj ntau dhau

Yog hais tias muaj ntau dhau ntawm cov tshuaj insulin nrog lyspro, kev ua rau lub ntsej muag ntshav qab zib: tsim ua pa, tshaib plab, tawm hws, tshee tshee, mob taub hau, tachycardia, kiv taub hau, ntuav, pom kev plooj, tsis meej pem, tsis nco qab, tuag.
Cov teeb meem me me ntawm lub cev tsis muaj ntshav qab zib yog nres los ntawm kev noj ntawm cov piam thaj, cov piam thaj, cov khoom uas muaj suab thaj (tus neeg mob ib txwm qhia kom muaj tsawg kawg 20 g ntawm qabzib nrog nws)
Kev kho cov ntshav qog ntshav me ntsis tuaj yeem nqa tawm los ntawm kev siv tshuaj subcutaneous lossis intramuscular ntawm glucagon nrog kev noj haus ntxiv ntawm cov carbohydrates tom qab ua kom tus neeg mob tus mob, dextrose (kua nplaum) daws yog muab rau cov neeg mob uas tsis teb rau glucagon.
Yog tias tus neeg mob tsis nco qab, tom qab ntawd kev noj qab haus huv subcutaneous lossis intramuscular ntawm glucagon yog qhov tsim nyog, thaum tsis muaj glucagon lossis qhov tshuaj tiv thaiv rau nws txoj kev tswj hwm, kev daws teeb meem dextrose yuav tsum tau txhaj tshuaj rau tom qab, tom qab rov qab nco qab, tus neeg mob yuav tsum tau muab cov zaub mov uas muaj protein ntau, ntxiv kev soj ntsuam ntawm tus neeg mob thiab kev noj haus carbohydrate yog qhov tsim nyog rau kev tiv thaiv ntawm kev rov ua dua ntawm hypoglycemia, nws yog ib qho tsim nyog yuav tau qhia rau tus kws kho mob uas tau mus kawm txog kev mob ntshav qab zib yav dhau los.

Qhia txog ntawm cov tshuaj

Tsis zoo li lwm cov tshuaj thaiv kab mob luv luv, Insulin Lizpro pib thiab nres nws qhov teebmeem sai. Xws li cov nyhuv ntawm cov tshuaj yog tshwm sim los ntawm kev nrawm ntawm nqus, yog li koj tuaj yeem nqa nws tam sim ntawd ua ntej noj mov. Qhov nqus ntawm kev pib thiab qhov pib ntawm kev sib kis tau cuam tshuam los ntawm qhov chaw nyob ntawm lub cev uas qhov kev txhaj tshuaj tau ua. Cov tshuaj tawm nws cov nyhuv ntau tshaj plaws ib nrab teev tom qab kev tswj hwm, thaum tswj qhov theem siab no rau 2 teev. Hauv lub cev, cov tshuaj muaj txog 4 teev.

Nyob rau hauv nws cov muaj pes tsawg leeg, "Insulin Lizpro" muaj cov khoom qub ib yam uas muaj kev ua haujlwm, nrog rau qee yam tshuaj txuam nrog dej. Cov tshuaj nws tus kheej yog cov tshuaj pob tshab uas tsis muaj kab mob uas tau muab tshuaj rau pob ntseg thiab subcutaneously. Lub tshuaj Insulin Lizpro "tau ntim rau hauv cov thawv ntawv hauv cov hlwv los yog cov xaum xaum tshwj xeeb uas muaj tsib cartridges ntawm 3 ml ntawm cov tshuaj.

"Insulin Lizpro" yog tshuaj rau:

ntshav qab zib hom 1, yog tias lub cev tsis zam rau lwm cov insulins,
nce ntxiv nyob rau hauv lub cev, uas tsis kho los ntawm lwm cov insulins,
ntshav qab zib hom 2, yog tias tsis tuaj yeem noj tshuaj kom txo tau cov ntshav qab zib,
lub impossibility ntawm assimilation los ntawm lub cev cov ntaub so ntswg ntawm lwm yam insulins,
phais kev ua haujlwm
lub xub ntiag ntawm concomitant mob ntshav qab zib mellitus

Qhov ntau npaum ntawm cov tshuaj "Insulin Lizpro" yog tus kws kho mob sau tseg. Nws yog suav raws li koj cov piam thaj hauv ntshav. Cov koob tshuaj txhua hnub yuav tsum tau nce ntxiv yog tias tus neeg mob muaj kab mob kis, nce hauv kev ntxhov siab hauv lub siab, qhov nce ntawm cov carbohydrates hauv zaub mov, thiab kev hloov pauv ntawm kev ua haujlwm hauv lub cev. Daim ntawv sau yuav ua tau nyob rau hauv kev sib xyaw nrog lwm cov tshuaj insulins.

Cov kws kho mob cov lus

Kev npaj tshuaj insulin yog qhov tsim nyog rau cov neeg mob ntshav qab zib hom 1 thiab rau 40% ntawm cov neeg mob uas mob hom mob thib ob.Cov tshuaj insulin yog polypeptide hormone. Raws li txoj cai, cov tshuaj tau muab tshuaj subcutaneously, tab sis thaum muaj xwm txheej ceev, kev siv tshuaj intramuscular lossis leeg ntshav yog ua tau. Nws qhov nqus ntshav ncaj qha nyob ntawm qhov chaw txhaj tshuaj, kev ua haujlwm ntawm cov leeg, cov yam ntxwv ntshav txaus thiab txheej txheem kev txhaj tshuaj.

Kev sib cuag cov receptors ntawm cell qog, cov tshuaj hormones pib ua rau nws lub zog tshwm sim:

Kev ua kom ntshav qabzib tsawg.
Ua kom cov glycogen synthesis.
Kev pom kev tsim ntawm ketone lub cev.
Kev txwv tsis pub muaj suab thaj los ntawm kev sib txuas nrog cov tsis muaj carbohydrate.
Kev ua kom muaj qhov tsim ntawm triglycerides thiab qis lipoproteins.
Kev txwv tsis pub cov rog rog vim qhov tsim los ntawm cov roj ntsha los ntawm carbohydrates.
Tsim kho glycogen, uas ua raws li lub zog cia ntawm lub cev.

Kev npaj rau kev kho tshuaj insulin yog cais raws lawv cov keeb kwm:

1. Cov tsiaj (nqaij npuas) - Insulrap GPP, Ultralente, Ultralente MS, Monodar Ultralong, Monodar Ntev, Monodar K, Monosuinsulin.
2. Tib neeg (semi-hluavtaws thiab engineering caj) - Actrapid, Novorapid, Lantus, Humulin, Humalog, Novomiks, Protafan.
3. Cov khoom cua sib txuam - Lizpro, Aspart, Glargin, Detemir.

Cov tshuaj tau muab faib los ntawm lub sijhawm ua:

Cov tshuaj insulin ultrasonic

Raug rho tawm sai dua li lwm hom tshuaj. Nws pib ua raws li 10-20 feeb tom qab kev tswj hwm, ua rau txo cov ntshav qab zib. Cov peev txheej siab tshaj plaws tsim tawm hauv 30-180 feeb thiab kav ntev li 3-5 teev.

Ob-theem sib xyaw ntawm kev kub ceev hauv insulin thiab kev tawm tsam tshuaj tiv thaiv ntawm kev ncua ntev. Cov tshuaj yog cov DNA recombinant analogue ntawm tib neeg cov tshuaj hormones, txawv tsuas yog rov qab qib ntawm cov proline thiab lysine amino acid seem. Regulates glucose metabolism thiab muaj cov nyhuv anabolic.

Equimolar rau tib neeg cov tshuaj insulin. Kev nkag mus rau hauv cov leeg nqaij ua kom nrawm nrawm hloov mus rau cov piam thaj thiab amino acids mus rau rog. Nws siv sijhawm 15 feeb tom qab tswj hwm. Qhov siab nqus tau tso cai rau koj siv cov tshuaj kom sai ua ntej noj.

Kev ntsuas rau kev siv: mob ntshav qab zib mellitus ntawm thawj hom, intolerance rau tshuaj ntawm lwm hom, postprandial hyperglycemia (tsis tuaj yeem kho tsis tau), nrawm hauv zos cuam tshuam ntawm cov tshuaj hormones ntawm lub txiav. Ntshav qab zib Hom 2, tiv taus cov tshuaj hypoglycemic hauv qhov ncauj, cuam tshuam cov kab mob sib kis, kev phais mob.
Txoj kev thov thiab muab ntau npaum li cas: tau txiav txim siab ntawm tus kheej rau txhua tus neeg mob, nyob ntawm qib glycemia hauv cov ntshav. Cov tshuaj raug muab tsuas yog subcutaneously. Yog tias tsim nyog, nws tuaj yeem ua ke nrog cov tshuaj kho mob ntev los yog sulfonylureas rau kev tswj hwm qhov ncauj.
Cov Txheej Txheem: Txoj kev tsis lees paub rau cov tshuaj, insulinoma.
Cov mob tshwm sim: kev fab tshuaj, lipodystrophy, hypoglycemia, hypoglycemic coma, ua txhaum cai ib ntus ntawm kev tshem tawm.
Noj ntau dhau: ua rau lub cev qaug zog, tsaug zog thiab qaug zog, tawm hws ntau ntau, tawm tsam, tachycardia, kev tshaib plab, qhov ncauj ntawm lub cev, mob taub hau, ntuav thiab xeev siab, ua tsis taus pa thiab mob siab. Pom kev tsis hnov lus, nriaj, glycemic coma.

Kev kho mob ntawm cov tsos mob tsis zoo thiab kev siv ntau tshaj muaj xws li subcutaneous, i / m lossis iv kev tswj hwm ntawm glucagon, iv kev tswj hwm ntawm hypertonic dextrose tov. Nrog rau kev txhim kho hypoglycemic coma, kev tswj xyuas lub dav hlau ntawm 40 ml ntawm 40% dextrose kev daws teeb meem yog qhia txog thaum tus neeg mob tawm ntawm lub cev tsis xeev.

Ib qho khoom sib piv ntawm tib neeg cov tshuaj hormones nrog ultrashort kev txiav txim siab. Qhov kev npaj tau tau los ntawm kev siv DNA thev naus laus zis thev naus laus zis siv kev ua ntawm Saccharomyces cerevisiae strain. Nws muaj cov nyhuv hypoglycemic. Nws pib ua 10-20 feeb tom qab tswj hwm subcutaneous thiab nce mus txog nws cov txiaj ntsig kho siab kawg tom qab 1-3 teev.

Nws yog siv rau ntshav qab zib mellitus ntawm thawj thiab hom thib ob. Aspart tsuas yog siv rau kev tswj hwm subcutaneous, kev noj tshuaj yog txiav txim los ntawm tus kws endocrinologist. Cov tshuaj yog contraindicated nyob rau hauv cov ntaub ntawv ntawm hypoglycemia thiab hypersensitivity rau nws lub Cheebtsam. Nws tsis yog siv los kho mob rau cov neeg mob hnub nyoog qis dua 6 xyoo, nrog rau thaum cev xeeb tub thiab lactation.

Thaum tus neeg noj ntau dhau, muaj cov tsos mob ntawm lub qog ntshav qab zib, kev huam yuaj thiab muaj qhov pheej hmoo ntawm qhov tshwm sim hypoglycemic coma. Txhawm rau tshem tawm cov ntshav qog ntshav qab zib thiab ua kom qhov xwm txheej zoo li qub, nws txaus los noj qab zib lossis zaub mov nplua nuj hauv kev zom cov zaub mov uas yooj yim. Lwm cov xwm txheej, kev tswj hwm ntawm 40% kev daws teeb meem yog qhov tsim nyog.

, , , , , ,

Kev daws rau subcutaneous thawj coj. Nws yog qhov sib txig ntawm tib neeg cov kua dej, sib haum rau nws hauv lub zog ntawm kev ua. Nws tau nce kev ua si, tab sis lub sijhawm luv luv ntawm kev nqis tes ua hauv kev sib piv nrog tib neeg lub cev.

Nws siv los them rau cov roj metabolism hauv lub cev uas tsis muaj cov tshuaj insulin. Pom zoo siv rau hauv kev kho mob menyuam yaus muaj hnub nyoog ntau dua 6 xyoo. Nws yog muab tshuaj subcutaneously 15 feeb ua ntej lossis tom qab noj mov. Qhov ntau npaum li cas thiab cov chav kawm ntawm kev kho yog txiav txim los ntawm tus kws kho mob koom nrog, tus kheej rau txhua tus neeg mob.
Cov tshuaj tiv thaiv tsis haum: hypersensitivity rau glulisin lossis lwm yam tshuaj ntawm cov tshuaj. Nrog rau kev saib xyuas tshwj xeeb yog siv rau cov poj niam cev xeeb tub thiab cov neeg mob lub sijhawm pub mis.
Cov kev mob tshwm sim: hypoglycemia thiab lwm yam teeb meem ntawm lub cev zom zaub mov, xeev siab thiab ntuav, txo qis qhov muag, pom lub qhov muag, qhov tsis haum ntawm qhov chaw txhaj tshuaj. Qee qhov tsis tshua muaj, nws muaj peev xwm tsim kev tsis haum xaum qhuav, mob lub hauv siab hauv siab, anaphylactic kev hloov.
Kev noj ntau dhau yog pom tshwm los ntawm cov tsos mob rau me ntsis lossis mob ntshav nce siab ntau. Hauv thawj kis, cov piam thaj lossis piam thaj muaj cov khoom yog qhia rau kev kho. Hauv rooj plaub thib ob, tus neeg mob tau txais tshuaj intramuscular lossis intravenous drip ntawm glucagon lossis dextrose.

Luv luv (siv cov tshuaj insulin rau tib neeg) - kev kho mob muaj txiaj ntsig tshwm sim tsis pub dhau 30-50 feeb tom qab kev tswj hwm. Lub ncov ntawm kev ua ntev ntev li 1-4 teev thiab kav 5-8 teev.

, , , , ,

Soluble Human Genetic Engineering

Txhaj tshuaj tov uas suav nrog tib neeg caj engineering engineering insulin, glycerol, metacresol thiab lwm yam. Nws muaj luv luv hypoglycemic nyhuv. Kev nkag mus rau hauv lub cev cuam tshuam nrog ib qho kev tshwj xeeb rau sab nraud cytoplasmic membrane ntawm cov hlwb.

Txhawb nqa qhov tsim ntawm kev tsim cov tshuaj insulin. Stimulates txheej txheem intracellular, kev sib txuas ntawm cov enzymes tseem ceeb. Qhov pib ntawm kev ua ntawm cov tshuaj tau muab sau tseg 30 feeb tom qab kev tswj hwm, thiab cov txiaj ntsig siab tshaj plaws tsim tawm hauv 2-4 teev, lub sijhawm ua haujlwm yog 6-8 teev.

Kev Qhia: hom ntshav qab zib hom 1 thiab tsis-insulin-ywj siab daim ntawv ntawm tus kab mob, cov kab mob sib kis, cov xwm txheej uas yuav tsum tau ua kom yoo mov tsis ua rau cov metabolism.
Kev noj tshuaj thiab kev tswj hwm: subcutaneously, intramuscularly lossis intravenously 30 feeb ua ntej noj mov nrog cov ntsiab lus siab ntawm carbohydrates. Kev siv tshuaj rau txhua hnub yog los ntawm 0.5 txog 1 IU / kg lub cev hnyav.
Cov tshuaj tiv thaiv tsis txaus: hypersensitivity rau lub Cheebtsam ntawm cov tshuaj, hypoglycemia, cev xeeb tub thiab lactation.
Cov kev mob tshwm sim: nce tawm hws thiab ntxhov siab, palpitations, tshee ntawm lub extremities, kev tshaib kev nqhis, daim tawv nqaij hauv lub qhov ncauj thiab lwm cov tsos mob hypoglycemic. Cov tshuaj tiv thaiv hauv zos: o ntawm thaj chaw txhaj tshuaj, khaus, lipodystrophy, kev fab tshuaj, tawm pob.
Overdose: muaj cov tsos mob zoo xws li kev phiv tshuaj. Nrog rau kev txhim kho hauv lub xeev hypoglycemic, cov zaub mov uas muaj carbohydrate ntau yog pom zoo, thiab muaj mob loj, kev qhia txog dextrose lossis glucagon tov.

Biosulin muaj nyob rau hauv hwj ntawm 10 ml txhua thiab hauv cartridges ntawm 3 ml.

Ib cov tshuaj uas them rau cov tsis muaj txaus ntawm cov tshuaj insulin hauv cov ntshav qab zib mellitus. Nws muaj ob peb daim ntawv uas sib txawv hauv feem pua ntawm cov tshuaj nruab nrab ntawm cov tshuaj insulin thiab cov tshuaj tiv thaiv. Txhua hom tau nws tus kheej pharmacokinetics, uas yog, yam ntxwv ntawm kev faib khoom hauv lub cev. Txhua daim foos tau tshwm sim los ntawm qhov pib sai thiab nruab nrab lub sijhawm ua.

Insuman Comb 15/85 - yog nquag 30-45 feeb tom qab kev tswj hwm, qhov kho tau zoo tshaj plaws tau tshwm sim tom qab 3-5 teev. Lub sijhawm tiv thaiv yog 11-20 teev.
Insuman Comb 25/75 - pib ua 30 feeb tom qab thov, qhov siab tshaj plaws pib tom qab 1.5-3 teev, lub sijhawm ua yog 12-18 teev.
Insuman Comb 50/50 - ua 30 feeb tom qab tswj hwm, qhov siab tshaj plaws tau pom tom qab 1-1.5 teev, lub sijhawm ua yog 10-16 teev.

Nws yog siv rau cov tshuaj insulin-tiv thaiv kev mob ntshav qab zib. Kev daws yog muab tshuaj subcutaneously ib teev ua ntej noj mov. Qhov ntau npaum li cas yog teem los ntawm tus kws kho mob tuaj koom.

Cov kev mob tshwm sim: tawv nqaij ua xua, lipodystrophy, insulin tsis kam, mob raum, mob lub cev ntau dhau. Overdose muaj qhov zoo sib xws, tab sis tshaj tawm cov tsos mob symptomatology. Txoj kev tiv thaiv tsis sib xws: txo tshuaj tiv thaiv mus rau cov tshuaj ntawm cov tshuaj, mob ntshav qab zib ua rau tsis nco qab tuaj. Muaj nyob rau hauv daim ntawv ntawm kev ncua rau kev txhaj tshuaj hauv vials ntawm 10 ml txhua.

Kev siv tshuaj insulin nrog cov txheej txheem monocomponent thiab luv luv. Kev ua kom zoo dua tuaj 30 feeb tom qab kev tswj hwm thiab nce mus txog nws qhov siab tshaj plaws hauv 2-5 teev. Kev kho mob nyhuv ntev rau 6-8 teev.

Kev qhia rau kev siv: mob ntshav qab zib insulin, kev kho mob ntawm cov neeg mob uas tsis txaus siab rau lwm hom tshuaj, kev phais yav tom ntej hauv cov neeg mob uas muaj hom mob ntshav qab zib thib ob, lipodystrophy.
Txoj kev ntawm daim ntawv thov: yog tias cov tshuaj tau sau hauv nws daim ntawv ntshiab, tom qab ntawd nws raug tswj 3 zaug hauv ib hnub subcutaneously, intramuscularly lossis intravenously. 30 feeb tom qab txhaj, koj yuav tsum noj zaub mov. Qhov ntau thiab tsawg yog txiav txim los ntawm tus endocrinologist, tus kheej rau txhua tus neeg mob.
Qhov tshwm sim: qhov txo qis hauv cov ntshav qab zib, cov tawv nqaij liab ntawm thaj chaw txhaj tshuaj thiab khaus, ua xua ntawm daim tawv nqaij.
Cov tshuaj tiv thaiv kom tsis txhob mob: cov qog hormonal ntawm lub txiav, mob ntshav qab zib. Siv thaum cev xeeb tub thiab lactation yog ua tau tsuas yog nrog cov tshuaj kho mob.

Actrapid NM muaj nyob rau hauv ampoules ntawm 10 ml ntawm cov khoom muaj sia nyob hauv txhua.

Brinsulrapi

Ib qho yeeb tshuaj luv luv, qhia nws cov haujlwm 30 feeb tom qab kev tswj hwm subcutaneous. Kev kho mob siab tshaj plaws tsim kho tau hauv 1-3 teev thiab kav ntev txog 8 teev.

Kev siv rau: hom 1 thiab 2 mob ntshav qab zib hauv menyuam yaus thiab neeg laus, ua rau cov tshuaj tiv thaiv ntshav qab zib hauv qhov ncauj.
Txoj kev ntawm daim ntawv thov: qhov ntau npaum li cas ntawm cov tshuaj hormones rau kev tswj hwm subcutaneous yog txiav txim los ntawm tus kws kho mob mus kawm, ib tus zuj zus rau txhua tus neeg mob. Kev daws yog txhaj tam sim tom qab sau mus rau hauv cov phwj. Yog tias qhov koob tshuaj txhua hnub yog ntau dua li 0.6 U / kg, tom qab ntawd cov tshuaj tau muab faib ua ob zaug thiab txhaj rau hauv qhov sib txawv ntawm lub cev.
Cov kev mob tshwm sim: cov tawv nqaij ua pob, mob caj dab, mob anaphylactic, lub cev lipodystrophy, hloov mus rau lwm qhov tsis raug, qhov nqaij hyperemia ntawm qhov chaw txhaj tshuaj.
Cov Txheej Txheem: Tus neeg tsis kam txais ua ke rau cov tshuaj, cov kev mob hypoglycemic. Kev kho mob thaum cev xeeb tub thiab lactation tsuas yog ua tau rau kev kho mob nkaus xwb. Nws yog siv nrog kev ceev faj thaum muaj kev ua haujlwm hauv lub cev lossis hlwb ntau ntxiv.

, ,

Neej Neeg P100

Kev ua yeeb yaj kiab luv luv tib neeg ib nrab hluavtaws cov kua dej. Nws cuam tshuam nrog receptors ntawm cytoplasmic cell week, ua ib qho insulin-receptor complex uas txhawb cov txheej txheem intracellular.

Kev kho cov ntshav qab zib ib txwm nyob ntawm kev nce ntxiv hauv kev thauj mus los tso rau hauv cov tshuaj no, txhim kho kev nqus thiab assimilation ntawm cov ntaub so ntswg. Cov tshuaj pib ua 30 feeb tom qab kev tswj hwm thiab nce mus txog qhov siab tshaj plaws tom qab 1-2 teev, qhov kev kho mob cuam tshuam rau 5-7 teev.

Kev taw qhia rau kev siv: mob ntshav qab zib ntawm hom thawj thiab hom thib ob. Ib nrab lossis ua tiav tsis kam rau cov tshuaj hypoglycemic hauv qhov ncauj, ketoacidosis uas mob ntshav qab zib, mob ntshav qab zib hauv lub cev, mob ntshav qab zib hauv lub cev thaum hloov mus rau lub sij hawm ntev insulin.
Txoj kev ntawm kev coj thiab ntau npaum li cas: cov tshuaj yog npaj rau subcutaneous, intramuscular thiab leeg thawj tswj hwm. Qhov nruab nrab qhov ntau npaum li cas yog los ntawm 0.5 txog 1 IU / kg lub cev hnyav. Qhov tshuaj hormones no siv 30 feeb ua ntej noj mov hauv cov carbohydrates. Cov tshuaj txhaj yuav tsum nyob ntawm chav tsev sov. Yog tias cov tshuaj tau hais tseg rau kev kho mob monotherapy, ces ntau zaus ntawm kev tswj hwm yog 3-5 zaug hauv ib hnub.
Cov tshuaj tiv thaiv tsis txaus: ib tug neeg tsis kam ua rau cov tshuaj, cov tsos mob ntawm tus mob ntshav qab zib. Siv thaum cev xeeb tub yog txwv tsis pub, kev txhaj tshuaj thaum pub niam mis yog ua tau rau kev kho mob nkaus xwb.
Cov kev mob tshwm sim: blanching ntawm daim tawv nqaij, nce tawm hws, palpitations, tshee ntawm lub siab, ntxhov siab, xeev siab thiab ntuav, mob taub hau. Ua xua rau ntawm qhov chaw txhaj tshuaj nws kuj muaj peev xwm ua tau.
Overdose: hypoglycemic lub xeev ntawm sib txawv heev. Txoj kev kho yog muaj noj cov suab thaj lossis cov khoom noj uas muaj carbohydrate. Hauv cov xwm txheej hnyav, qhov kev qhia ntawm 40% daws teeb meem ntawm dextrose lossis glucagon yog qhia.

Humodar P100 raug tso tawm hauv 10 ml vials thiab hauv cov cartridges ntawm 3 ml ntawm kev daws txhua.

Berlinsulin N ib txwm U-40

Cov tshuaj noj nrog cov nyhuv hypoglycemic. Hais txog cov tshuaj ntawm qhov kev txiav txim sai thiab luv. Kev kho mob siab tshaj plaws tshwm sim tom qab 1-3 teev thiab kav ntev li 6-8 teev.

Nws yog siv los kho txhua hom mob ntshav qab zib thiab ntshav qab zib tsis xeev plab. Koob tshuaj yog teem ib leeg zuj zus rau txhua tus neeg mob. Raws li txoj cai, cov tshuaj yog muab tshuaj subcutaneously 10-15 feeb ua ntej noj mov 3-4 zaug hauv ib hnub. Cov koob tshuaj rau txhua hnub yog 6-20 units. Rau cov neeg mob uas muaj lub siab ntsws tsis zoo rau qhov tshuaj, qhov ntau dua yog txo, nrog qhov mob rhiab, lawv nce.

Cov tshuaj yog contraindicated nyob rau hauv cov ntaub ntawv ntawm intolerance mus rau nws lub Cheebtsam thiab cov cim qhia ntawm hypoglycemia. Cov tsos mob tshwm sim los ntawm cov tsos mob ntawm daim tawv nqaij hauv zos, ua kom tsis zoo rau kev noj qab haus huv.

Nruab Nrab Sijhawm Insulins

Maj mam nqus thiab muaj cov nyhuv kho tau 1-2 teev tom qab txhaj tshuaj subcutaneous. Qhov siab tshaj plaws tau tiav nyob rau hauv 4-12 teev, lub sijhawm ua haujlwm yog 12-24 teev.

Ncua rau lub subcutaneous thawj coj. Nws ua kom lub phosphatidylinositol system, hloov kev thauj cov kua nplaum. Ntau cov poov tshuaj nkag mus rau hauv lub cell. 1 ml ntawm kev ncua kev kawm muaj 40 IU ntawm tib neeg cov tshuaj insulin ntawm biosynthetic keeb kwm. Nws yog siv rau cov tshuaj insulin-tiv thaiv ntshav qab zib mellitus, rau kev ua xua rau lwm hom insulin, qhia txog kev mob ntshav qab zib ntawm ntshav qab zib.

Cov tshuaj yog siv rau subcutaneous thiab intramuscular thawj coj. Cov koob tshuaj thiab ntau npaum li cas ntawm kev txhaj tshuaj yog txiav txim los ntawm tus kws kho mob koom nrog, ua rau txhua tus neeg mob. Isofan yog contraindicated hauv hypoglycemic thiab coma. Cov kev mob tshwm sim los ntawm cov kev tshaib kev nqhis, ua haujlwm dhau, tshee ntawm lub siab, ua xua.

Monotard MS

Kev siv tshuaj insulin nrog qhov nruab nrab ncua sijhawm. Muaj 30% amorphous thiab 70% crystalline lawm. Cov nquag ua haujlwm yog zinc raug tshem tawm ntawm monocomponent porcine insulin. Nws pib ua yeeb yaj kiab 2.5 teev tom qab kev tswj hwm, qhov ua haujlwm siab tshaj plaws tsim tawm tom qab 7-15 teev thiab tawm tsam ib hnub.

Kev siv rau kev siv: txhua hom mob ntshav qab zib mellitus, ua rau cov tshuaj tiv thaiv kab mob hauv lub qhov ncauj, ntau yam mob ntshav qab zib mellitus, phais mob, cev xeeb tub thiab lactation.
Txoj kev ntawm daim ntawv thov: qhov koob tshuaj yog xaiv los ntawm tus kws kho mob tshwj xeeb rau txhua tus neeg mob. Cov tshuaj yog txhaj rau tob tob subcutaneously, txhua zaus hloov chaw txhaj tshuaj. Yog tias cov koob tshuaj ntau dua li 0.6 U / kg, ces nws yuav tsum tau muab faib ua ob qhov kev txhaj tshuaj rau ntau qhov chaw. Cov neeg mob uas tau txais ntau tshaj li 100 ib pawg ntawm cov tshuaj ib hnub yuav raug coj mus pw hauv tsev kho mob.
Cov kev mob tshwm sim: hypoglycemic tej yam kev mob ntawm ntau yam mob hnyav, precoma, coma. Hyperemia ntawm qhov chaw txhaj tshuaj, kev tawm tsam ntawm daim tawv nqaij.
Cov tshuaj tiv thaiv: hypoglycemic tej yam kev mob thiab hypoglycemic coma.

Monotard MS muaj nyob rau hauv daim ntawv ntawm ncua kev kawm rau kev txhaj tshuaj hauv 10 ml vials.

Insulong SPP

Hypoglycemic tus neeg sawv cev ntawm nruab nrab ntev. Nws yog siv los kho ntshav qab zib 1 thiab 2 daim ntawv. Cov tshuaj yog siv rau kev txhaj tshuaj subcutaneous hauv thaj chaw hauv ncej puab; nws tseem raug tso cai los tswj cov tshuaj rau hauv pem hauv ntej plab phab ntsa, pob tw, thiab deltoid leeg ntawm lub xub pwg. Kev noj tshuaj yog xam los ntawm tus neeg endocrinologist, tsom mus rau theem ntawm cov piam thaj hauv tus neeg mob cov ntshav thiab lwm yam ntxwv ntawm nws lub cev.

Cov tshuaj yog contraindicated nyob rau hauv cov ntaub ntawv ntawm hypersensitivity rau nws lub Cheebtsam, hypoglycemia. Cov kev mob tshwm sim yog qhia los ntawm kev ua txhaum ntawm kev thim rov qab thiab o ntawm cov nqua. Yog tias muaj teeb meem tsis zoo thaum kho mob lossis siv tshuaj ntau dua, yuav ua rau lub qog ntshav nce ntshav. Kuj tseem muaj peev xwm nyob hauv zos tom qab txhaj tshuaj: liab liab, o thiab khaus.

Ntev insulins

Nws pib ua yeeb yam 1-6 teev tom qab tswj hwm. Tusyees txo cov ntshav qabzib. Nws muaj qhov ua tiav ntawm qhov tsis pom tseeb ntawm lub zog thiab tseem siv tau 24 teev. Tso cai rau koj kom txhaj ib zaug 1 zaug nyob rau ib hnub.

Kev npaj tshuaj insulin hypoglycemic nrog cov nquag ua haujlwm yog glargine (ib qho tshuaj ntawm tib neeg lub cev). Nws muaj tsawg solubility nyob rau hauv qhov nruab nrab thaj chaw. Thaum muab tshuaj subcutaneously, cov kua qaub yog neutralized thiab ua microprecipitate, tso cov tshuaj insulin.

Cov lus qhia rau kev siv: insulin-tiv thaiv kev mob ntshav qab zib hauv cov neeg laus thiab cov menyuam hnub nyoog tshaj 6 xyoo.
Txoj kev ntawm daim ntawv thov: lub sijhawm ntev ua raws li kev qhia ntawm cov nquag hloov mus rau hauv cov rog muaj rog. Cov nyhuv ntawm cov tshuaj no tso cai rau koj siv nws ib hnub ib zaug. Koob tshuaj yog xam rau txhua tus neeg mob ib tus zuj zus.
Qhov tshwm sim: cov teeb meem ntawm cov khoom noj tsis haum rau lub cev sib txawv. Feem ntau, muaj kev txo qhov muag pom, lipoatrophy, lipohypertrophy, dysgeusia, kev tsis haum tshuaj hauv zos. Tsis tshua muaj tshwm sim, anaphylactic shock, myalgia, bronchospasm tshwm sim.
Cov tshuaj tiv thaiv tsis txaus: hypersensitivity rau yeeb tshuaj, hypoglycemia, mob ntshav qab zib ketoacidosis. Cov tshuaj tsis pom zoo rau kev kho mob ntawm poj niam cev xeeb tub thiab menyuam yaus.
Overdose: kev tsis ua raws li kev noj haus hem thawj qhov kev txhim kho ntawm lub caij nyoog ntev ntawm cov mob ntshav qab zib ntau, uas yog qhov txaus ntshai rau tus neeg mob. Cov tsos mob tsis muaj zog nres qhov kom tsawg ntawm cov carbohydrates. Thaum muaj mob hnyav, tswj kev tso ntshav ntawm cov tshuaj muaj qabzib nyob nrog.

Lantus muaj nyob rau hauv daim ntawv ntawm kev daws rau kev txhaj tshuaj, nyob rau hauv 3 ml cartridges.

Levemir Penfill

Antidiabetic tus neeg sawv cev, ib qho analogue ntawm tib neeg basal hormone nrog kev ua ntev. Cov nyhuv ntev ntev yog nyob ntawm kev sib cuam tshuam ntawm cov roj molecules ntawm cov tshuaj nquag nrog albumin los ntawm cov saw hlau ntawm cov roj ntsha ntawm qhov chaw txhaj tshuaj. Kev siv tshuaj hypoglycemic nyob rau 24 teev, tab sis kuj yuav txawv nyob ntawm qhov ntau npaum li cas. Lub sijhawm ntev ua rau tso cai siv cov tshuaj 1-2 zaug ib hnub.

Nws raug siv los kho hom ntshav qab zib 1. Qhov kev daws teeb meem yog muab cov tshuaj subcutaneously, qhov ntau npaum li cas yog xaiv tau rau txhua tus neeg mob, nyob ntawm qhov xav tau ntawm nws lub cev thiab cov yam ntxwv ntawm tus kab mob.
Cov kev mob tshwm sim: paler dua li daim tawv nqaij, tshee tshee ntawm qhov kawg, ua rau muaj kev poob siab, txhawj xeeb, tsaug zog, plawv dhia nrawm, tsis pom kev thiab tsis pom kev, ua pob txha caj qaum. Cov kev tawm tsam hauv zos nyob rau hauv daim ntawv ntawm cov nqaij mos o, ua pob, khaus, lipodystrophy thiab hyperemia ntawm daim tawv nqaij kuj tseem tuaj yeem. Ib qho overdose muaj cov tsos mob zoo sib xws. Kev kho yog muaj nyob rau hauv kev noj zaubmov uas muaj carbohydrate.
Cov tshuaj tiv thaiv: kom tsis haum rau cov tshuaj ntawm cov tshuaj. Siv thaum cev xeeb tub thiab lactation yog ua tau tsuas yog rau cov hom phiaj kho mob thiab nyob rau hauv kev tswj hwm nruj ntawm cov kws endocrinologist.

Levemir Penfill muaj nyob rau hauv 3 ml cartridges (300 units) nyob rau hauv daim ntawv ntawm kev daws teebmeem rau kev tswj hwm niam txiv.

Tresiba FlexTouch

Ib qho piv txwv ntawm tib neeg cov tshuaj hormones ntawm superlong kev ua. Tus txheej txheem ntawm kev ua ntawm cov tshuaj yog ua raws kev sib cuam tshuam nrog kev txais ntawm tib neeg cov tshuaj insulin. Qhov ua rau lub ntsej muag ntshav yog vim muaj kev siv cov kua nplaum ntau ntxiv los ntawm cov ntaub so ntswg tom qab cov tshuaj hormones khi rau cov receptors roj thiab cov leeg nqaij.

Cov tshuaj yog siv los kho mob ntshav qab zib hauv cov neeg laus thiab cov hluas, thiab cov menyuam yaus hnub nyoog qis dua 1 xyoos. Cov tshuaj yog siv rau kev coj noj coj ua, kev noj tshuaj yog xam los ntawm tus kws kho mob uas tuaj koom, ib tus zuj zus rau txhua tus neeg mob.
Cov Tshuaj Tiv Thaiv: kev tsis txaus ntseeg rau cov tshuaj, cev xeeb tub thiab lactation.
Qhov tshwm sim: hypoglycemia, kev tsis haum ntawm qhov chaw txhaj tshuaj, lipodystrophy. Kev tiv thaiv kab mob hauv lub nruab nrog cev, ua kom mob pob txha, thiab qhov mob txhaws yog qhov tuaj yeem. Ib qho overdose muaj cov tsos mob zoo sib xws. Txhawm rau tshem tawm cov tsos mob mob, nws raug nquahu kom noj cov khoom muaj piam thaj sab hauv. Yog tias hypoglycemia yog nyob rau hauv daim ntawv hnyav, yuav tsum tau qhia txog kev daws teeb meem dextrose.

Tresiba FlexTouch muaj nyob hauv cov koob txhaj tshuaj rau kev txhaj tshuaj subcutaneous ntawm 100 thiab 200 units / ml.

Ntxiv rau cov pab pawg saum toj no ntawm cov tshuaj, muaj cov sib xyaw ntawm cov tshuaj insulins ntawm ntau cov kev ua haujlwm ntev: aspart ob-theem NovoMix 30/50, FlexPen, Penfill, Lizpro, ob-theem Humalog Mix 25/50.

Kev taw qhia thiab cov lus qhia rau siv

Insulin Lizpro yog siv rau hauv kev kho mob rau cov neeg mob ntshav qab zib, tsis hais poj niam txiv neej thiab hnub nyoog li cas. Lub cuab yeej muab cov cim qhia tau zoo hauv qhov xwm txheej uas tus neeg mob coj tus yam ntxwv txawv txav, uas tshwj xeeb tshaj yog cov menyuam yaus.

Phau ntawv qhia tshuaj ntawm tes yog kws kho mob tshwj xeeb nrog:

Hom 1 thiab hom 2 mob ntshav qab zib mellitus - nyob rau tom kawg, tsuas yog thaum noj lwm yam tshuaj tsis coj zoo tshwm sim,
Hyperglycemia, uas tsis tau maj mam siv lwm cov tshuaj,
Npaj tus neeg mob rau kev phais,
Intolerance rau lwm cov tshuaj uas muaj cov tshuaj insulin,
Qhov tshwm sim ntawm pathological mob complicating chav kawm ntawm tus kab mob.

Cov txheej txheem ntawm kev tswj hwm tshuaj pom zoo los ntawm cov neeg tsim khoom yog subcutaneous, tab sis nyob ntawm qhov xwm txheej ntawm tus neeg mob, tus neeg sawv cev tuaj yeem muab rau ob leeg thiab intramuscularly. Nrog rau txoj kev subcutaneous, qhov chaw uas tsim nyog tshaj plaws yog lub duav, lub xub pwg, pob tw thiab lub plab.

Kev tswj hwm tas mus li ntawm Insulin Lizpro nyob rau tib lub sijhawm yog contraindicated, vim tias qhov no tuaj yeem ua rau kev puas tsuaj ntawm daim tawv nqaij qauv hauv daim ntawv ntawm lipodystrophy.

Tib ntu tsis tuaj yeem siv los tswj cov tshuaj ntau dua 1 zaug hauv ib hlis. Nrog rau kev tswj hwm subcutaneous, cov tshuaj yuav siv tau yam tsis muaj ib tus kws kho mob, tab sis tsuas yog tias cov koob tau tau xaiv yav tas los ntawm cov kws tshaj lij.

Lub sijhawm ntawm kev tswjhwm ntawm cov tshuaj kuj raug txiav txim los ntawm tus kws khomob mus koom, thiab nws yuav tsum raug saib xyuas nruj me ntsis - qhov no yuav tso cai rau lub cev kom hloov kho rau tsoomfwv, nrog rau muab lub sijhawm ntev ntawm cov tshuaj.

Xav tau koob hloov thaum lub sij hawm:

Hloov kev noj haus thiab hloov mus rau cov zaub mov tsis muaj roj lossis siab dua,
Kev ntxhov siab
Kis tau cov kab mob
Kev siv lwm cov tshuaj tsis meej
Hloov los ntawm lwm cov tshuaj muaj txiaj ntsig sai uas cuam tshuam rau cov piam thaj,
Qhov qhia raum tsis ua hauj lwm,
Cev xeeb tub - nyob ntawm peb lub hlis, lub cev xav tau cov insulin hloov, yog li nws tsim nyog
Mus ntsib koj tus kws kho mob tsis tu ncua thiab ntsuas koj qib qab zib.

Ua cov kev hloov kho txog kev noj tshuaj kuj tseem yuav tsim nyog thaum hloov chaw tsim tshuaj lub tuam txhab Insulin Lizpro thiab hloov chaw ntawm cov tuam txhab sib txawv, vim lawv txhua tus ua rau nws tus kheej hloov pauv ntawm qhov muaj pes tsawg leeg, uas yuav cuam tshuam rau cov txiaj ntsig ntawm kev kho mob.

Sab nraud thiab contraindications

Thaum teem tshuaj, cov kws kho mob yuav tsum coj mus rau hauv txhua tus cwj pwm ntawm tus neeg mob lub cev.

Insulin Lizpro yog cov neeg tsis sib haum:

Nrog rau kev nkag siab ntxiv rau lub ntsiab lossis ntxiv cov khoom siv txuam,
Nrog lub siab ntsuas rau qhov ntshav qab zib tsawg,
Hauv qhov muaj tshuaj insulinoma.

Thaum lub sijhawm siv cov tshuaj hauv cov ntshav qab zib, cov kev mob tshwm sim hauv qab no tuaj yeem pom:

Mob Hypoglycemia - yog qhov txaus ntshai tshaj plaws, tshwm sim vim kev xaiv tsis raug, nrog rau kev noj tshuaj rau tus kheej, tuaj yeem ua rau tuag lossis cuam tshuam tsis zoo ntawm lub hlwb kev ua ub no,
Lipodystrophy - tshwm sim los ntawm kev txhaj tshuaj hauv tib thaj chaw, rau kev tiv thaiv, nws yog ib qho tsim nyog los hloov lwm qhov chaw pom zoo ntawm daim tawv nqaij,
Kev ua xua - ua rau nws tus kheej nyob ntawm tus neeg mob lub cev, pib los ntawm liab ntawm qhov chaw txhaj tshuaj, xaus nrog kev poob siab anaphylactic,
Kev tsis sib haum ntawm lub qhov muag pom - nrog rau cov koob tshuaj tsis zoo lossis ib tus neeg tsis haum rau lub Cheebtsam, retinopathy (kev puas tsuaj rau lub laj kab ntawm lub qhov muag vim muaj kev puas siab puas ntsoog) lossis pom tseeb ib nrab, feem ntau feem ntau nws ua nws tus kheej thaum tseem yau lossis nrog kev puas tsuaj rau cov hlab plawv.
Cov tshuaj tiv thaiv hauv ib cheeb tsam - ntawm qhov chaw txhaj tshuaj, liab liab, khaus, liab thiab o tuaj yeem tshwm sim, uas dhau tom qab lub cev tau dhau los ua ib txwm muaj.

Qee cov tsos mob yuav pib tshwm tom qab lub sijhawm ntev. Yog tias muaj kev mob tshwm sim, nres siv tshuaj insulin thiab sab laj nrog koj tus kws kho mob. Yuav luag txhua qhov teeb meem feem ntau yog kho los ntawm kev hloov kho koob tshuaj.

Kev cuam tshuam nrog lwm yam tshuaj

Thaum sau ntawv yuav ntawm cov tshuaj Humalog, tus kws kho mob koom yuav tsum xav txog hom tshuaj uas koj tau noj lawm. Qee qhov ntawm lawv tuaj yeem ob leeg txhim kho thiab txo qis qhov kev ua haujlwm ntawm insulin.

Cov nyhuv ntawm Insulin Lizpro kho kom zoo dua yog tias tus neeg mob siv tshuaj thiab pab pawg hauv qab no:

MAO inhibitors,
Sulfonamides,
Ketoconazole,
Sulfonamides.

Nrog rau kev sib xyaw siv cov tshuaj no, nws yog ib qho tsim nyog yuav tau txo qis ntawm cov tshuaj insulin, thiab tus neeg mob yuav tsum, yog tias ua tau, tsis kam noj lawv.

Cov tshuaj yeeb dej hauv qab no tuaj yeem txo qhov kev ua tau zoo ntawm Insulin Lizpro:

Hormonal tshuaj tiv thaiv
Estrogens
Glucagon,
Nicotho.

Cov koob tshuaj ntawm cov tshuaj insulin hauv qhov xwm txheej no yuav tsum nce ntxiv, tab sis yog tias tus neeg mob tsis kam siv cov tshuaj no, nws yuav tsum hloov kho zaum ob.

Nws kuj tseem tsim nyog xav txog qee cov nta thaum kho nrog Insulin Lizpro:

Thaum xam xyuas qhov ntau npaum li cas, tus kws kho mob yuav tsum xav txog ntau npaum li cas thiab hom zaub mov twg tus neeg mob noj,
Hauv kab mob siab thiab mob hauv lub raum, cov tshuaj yuav tsum raug txo,
Humalog tuaj yeem txo qhov kev ua haujlwm ntawm cov dej ntws ntawm cov hlab ntsha cuam tshuam, uas cuam tshuam rau cov tshuaj tiv thaiv, thiab qhov no ua rau muaj kev phom sij, piv txwv, rau tus tswv tsheb.

Cov tshuaj Insulin Lizpro (Humalog) muaj tus nqi them tus nqi siab, vim tias cov neeg mob feem ntau mus nrhiav hauv cov duab tsis zoo.

Cov tshuaj hauv qab no tuaj yeem pom nyob rau hauv kev ua lag luam uas muaj tib lub hauv paus ntsiab lus ntawm kev ua:

Monotard
Protafan
Rinsulin
Mob siab
Actrapid.

Nws yog txwv tsis pub ywj siab los hloov cov tshuaj no. Ua ntej koj yuav tsum tau txais tswv yim los ntawm koj tus kws kho mob, vim kev haus tshuaj pab tus kheej tuaj yeem ua rau tuag taus.

Yog tias koj tsis ntseeg koj lub peev xwm ntawm cov khoom siv, ceeb toom cov kws tshaj lij txog qhov no. Cov tshuaj sib xyaw ntawm txhua cov tshuaj yuav txawv nyob ntawm tus tsim khoom lag luam, vim qhov ntawd qhov ua kom lub zog ntawm cov tshuaj ntawm tus neeg mob lub cev yuav hloov.

Qhov kev hais daws no feem ntau siv rau cov tsis muaj tshuaj insulin-hom mob ntshav qab zib (1 thiab 2), ntxiv rau kev kho rau menyuam yaus thiab poj niam cev xeeb tub. Nrog rau qhov tseeb qhov tseeb suav nrog, Humalog tsis ua kev mob tshwm sim thiab maj mam cuam tshuam rau lub cev.

Cov tshuaj muaj peev xwm muab tau los ua ob peb txoj hauv kev, tab sis feem ntau zoo li subcutaneous, thiab qee cov tuam ntxhab muab cov twj nrog cov txhaj tshwj xeeb uas ib tus neeg tuaj yeem siv txawm nyob hauv lub xeev tsis ruaj khov.

Yog tias tsim nyog, tus neeg mob ntshav qab zib tuaj yeem nrhiav tau cov tshuaj noj hauv cov chaw muag tshuaj, tab sis yog tsis muaj kev sib tham ua ntej nrog tus kws tshaj lij, lawv txoj kev siv txwv yog txwv tsis pub. Cov tshuaj Insulin Lizpro sib txuam nrog lwm cov tshuaj, tab sis qee qhov xwm txheej yuav tsum muaj kev hloov kho tshuaj.

Kev siv cov tshuaj tsis raug cai tsis raug ntxiv, tab sis tus neeg mob yuav tsum ua raws li kev coj tshwj xeeb uas yuav pab tau lub cev kom hloov mus rau qhov xwm txheej tshiab.

Yuav noj li cas INSULIN LIZPRO

Qhov kev txhaj tshuaj yog nqa tawm hauv qab daim tawv nqaij hauv qab plab, xub pwg, ncej puab lossis pob tw. Nws yog ib qho tsim nyog yuav tsum tau hloov chaw txhaj tshuaj kom tsis txhob txhaj rau ntau qhov chaw ntau dua ib hlis ib zaug. Kev saib xyuas yuav tsum tau saib xyuas thaum kev txhaj tshuaj kom tsis txhob ua kom cov hlab ntshav puas. Nws yog txwv tsis pub noj cov tshuaj rau lwm txoj kev dhau ntawm kev txhaj tshuaj.

Cov Yuav Tsum Muaj

Cov tshuaj "Insulin Lizpro" muaj qee qhov contraindications rau nws siv hauv:

ib tug neeg intolerance mus rau active tshuaj,
muaj mob qog hauv lub txiav,
ntshav qab zib tsawg

Nyob rau hauv qhov muaj mob hepatic lossis lub raum tsis ua haujlwm, cov tshuaj tsis txwv tsis pub siv, tab sis nws lub ntim yuav tsum tau tswj tas li.

Sab sij huam

Siv cov tshuaj insulin Lizpro, tus neeg mob yuav tsum tau npaj rau qhov tshwm sim ntawm qee qhov kev mob tshwm sim, tshwm sim ntawm daim ntawv tsis haum, kub taub hau me ntsis, pom tsis meej, txo cov ntshav qab zib, thiab poob phaus. Kev siv tshuaj ntau dhau ntawm cov tshuaj no tuaj yeem ua rau lub siab poob qis, txob taus, pw tsaug zog, mob taub hau, plooj tsis pom kev, cramps thiab ua rau rov qab.