Formine yog ib qho tshuaj tiv thaiv kab mob ntawm cov kawm biguanide

Tshis Extract Galega officinalis ) siv rau hauv kev kho mob ntshav qab zib hauv tshuaj kho mob hauv nruab nrab teb chaws Europe. Lub hom phiaj ntawm kev siv cov lus qhia yog tias cov zis ua rau lub ntsej muag tsawg dua (txo cov piam thaj hauv cov zis). Qhov kawg ntawm lub xyoo pua puv 19, isoamylene-guanidine tau pom nyob rau hauv cov extract. Hauv xyoo 1918, nws tau dhau los ua pov thawj tias guanidine muaj kev ua haujlwm hypoglycemic hauv cov tsiaj. Nyob rau tib lub sijhawm, nws muaj tshuaj lom ua rau daim siab.

Sintalin hloov |

Formine yog ib qho tshuaj tiv thaiv kab mob ntawm cov kawm biguanide

Cov lus qhia qauv tshuaj rau kev siv yog tus cwj pwm li ua tshuaj tiv thaiv kev ua kom zoo ntawm chav kawm biguanide. Cov peculiarity ntawm cov tshuaj yog nws cov versatility: ntsiav tshuaj tuaj yeem siv rau hauv kev kho mob ntawm hom 2 mob ntshav qab zib, noj Formin thiab cov uas nws hom rog tsis pub poob phaus tsuas yog los ntawm kev noj zaub mov thiab kis las.

Cov neeg mob ntshav qab zib feem ntau zam txoj kev kho kom yooj yim, qhov tsis xav ua yuav tshwm sim ntau dua yog tias cov lus qhia thiab cov cai uas kws kho mob sau tseg tsis ua raws. Cov lus qhia ntawm cov lus qhia ntawm lub xaib no tau yooj yim, ntxiv los ntawm kev txheeb xyuas thiab cov lus pom. Nws yog tsis yooj yim sua kom pom nws cov lus qhia rau kev coj tus kheej.

Dosage daim ntawv thiab cia tej yam kev mob

Sab nraud, cov tshuaj zoo li niaj zaus zoo li lub qe kheej kheej lub ncoo nrog cov kab sib faib tsis muaj qhov tshwj xeeb tsis hnov tsw lossis tsis hnov tsw. Cov ntsiav tshuaj tau ntim rau hauv cov hlwv, hauv ib lub thawv muaj peev xwm muaj 10 lossis 12 daim ntawm ntau qhov ntau: 0.5 g, 0.85 g lossis 1 g txhua. Lawv yog npaj rau kev siv qhov ncauj.

Cov tshuaj tsis tas yuav tshwj xeeb rau kev khaws cia. Hauv chav tsev kub (+ 25 ° C) kom deb ntawm lub teeb ci ntsa iab thiab cov menyuam yaus mloog, Formin tuaj yeem khaws cia rau 2 xyoo - lub neej txee no tau qhia ntawm pob. Hauv lub neej yav tom ntej, cov tshuaj yog raug pov tseg.

Tus txheej txheem ntawm kev ua ntawm formin

Qhov pib ua haujlwm tseem ceeb ntawm cov tshuaj yog metformin hydrochloride. Ntxiv nrog rau cov khoom tseem ceeb, tseem muaj cov neeg tsis paub nyob hauv cov lus muaj pes tsawg leeg: magnesium stearate, croscarmellose sodium, povidone.

Lub peev xwm ntawm Formetin, uas nws cov duab tuaj yeem pom hauv tshooj no, yog multivariate:

Lowers glycemia
Tsub kom cov cell hloov pauv mus rau insulin,
Nws inhibits qhov nqus ntawm cov suab thaj,
Tswj cov metabolism hauv lipid:
Tsis provoke hnyav nce.

Cov tshuaj tsis txhim kho kev tsim cov tshuaj tua kab mob endogenous, β-hlwb ntawm cov txiav, lub luag haujlwm rau nws cov khoom cua, tsis txhob thauj khoom ntau dhau. Metformin nrawm nrawm: qhov kawg hauv nws qhov kev tsom xam tau pom tom qab ob teev.

Lwm qhov zoo dua ntawm metformin yog nws cov koom haum tsis zoo nrog cov ntshav protein. Formmetin tsis yog qhov muaj txiaj ntsig rau kev txhim kho hypoglycemia. Cov nquag ua haujlwm txuam hauv cov leeg, raum, siab, qog qaub ncaug. Nws yog tawm tsuas yog los ntawm lub raum. Cumulation ntawm metformin yog ua tau nrog tsuas yog loj pathologies ntawm ob lub raum. Tom qab ib teev thiab ib nrab, kev tso tawm ntawm cov tshuaj nquag nrog zis pib.

Txij li thaum cov tshuaj muaj lub nra hnyav ntxiv rau cov kab mob genitourinary, qhov xwm txheej ntawm lub raum thiab ntshav qab zib yuav tsum kuaj xyuas tsawg kawg ob zaug hauv ib xyoos.

Yog tias xav tias muaj myalgia, lub sijhawm lactate hauv cov ntshav yuav tsum kuaj xyuas.

Yuav noj tshuaj li cas

Qhov kev txhaj tshuaj txhua hnub yog feem ntau muab faib ua ob zaug. Cov lus qhia meej dua yog npaj los ntawm tus kws kho mob uas koom nrog. Kev kho mob pib nrog kev txhaj tshuaj tsawg kawg nkaus (0.5-0.85 g / hnub), ib zaug ib asthiv endocrinologist tuaj yeem kho qhov kev siv tshuaj nyob ntawm kev soj ntsuam ntshav. Qhov siab tshaj plaws yog 3 pcs / hnub.

Metformin ib txwm noj 20 feeb ua ntej noj mov. Tom qab ntawd cov theem ntawm kev zom zaub mov thiab kev noj tshuaj ib yam nkaus.

Tsis noj zaub mov tom qab noj cov tshuaj yog qhov txaus ntshai: koj tuaj yeem ua rau cov piam thaj poob qis.

Formimetin yog dawb do los ntawm cov neeg mob ntshav qab zib uas tswj kev thauj khoom thiab cov txheej txheem nyuaj, vim nws tsis ua rau tsis muaj qhov cuam tshuam uas txo qis qhov kev mloog thiab qhov ceev ntawm cov tshuaj tiv thaiv.

Hauv kev kho txoj kev nyuaj, phiv yog ua tau, yog li ntawd, xws li nuances yuav tsum muaj kev pom tseeb los ntawm tus kws kho mob endocrinologist.

Metformin rau cov kev poob phaus: yuav ua li cas coj thiab ua tau zoo: cov lus qhia rau kev siv thiab tshuaj xyuas, twv kom meej txog kev noj qab haus huv ntawm iLive

Ntawm ntau cov kev noj haus tshuaj, Metformin tuaj yeem paub qhov txawv. Cov cuab yeej no, nrog kev siv tas li, tuaj yeem txo qhov hnyav hauv lub cev.

Metformin feem ntau qhia rau cov neeg mob ntshav qab zib, tab sis cov neeg rog rog tuaj yeem poob ceeb thawj los ntawm kev noj cov tshuaj no.

Cov tshuaj Metformin tsuas muaj nyob hauv daim ntawv ntawm cov ntsiav tshuaj rau kev tswj hwm qhov ncauj. Cov pob ntim muaj 30, 50, 60, 120 ntsiav tshuaj, nws tag nrho yog nyob ntawm lub teb chaws ntawm kev tsim khoom.

Qhov tseem ceeb tshuaj ntawm cov tshuaj no yog metformin. Pharmacological kev txiav txim ntawm cov ntsiav tshuaj yog hypoglycemic.

Qhov kev ua ntawm Metformin rau ntawm lub cev:

Carbohydrates yog ua tiav sai, uas ua rau poob phaus,
Nce tus nqi ntawm oxidation ntawm fatty acids,
Txo cov hnyuv nqus ntawm carbohydrates,
Nws tsis pab txhawb kev tsim cov tshuaj insulin, uas txo cov kev xav ntawm kev tshaib plab,
Lowers ntshav qab zib.

Txawm li cas los xij, ua ntej noj tshuaj, nws yog ib qho tsim nyog yuav tsum ua tib zoo kawm tag nrho cov khoom ntawm cov tshuaj.

Nws yog ua tau kom txo qhov hnyav nrog Metformin tsuas yog tias cov tshuaj insulin txaus tsim hauv lub cev. Kev siv suab thaj yuav tsis ncua rau daim duab hauv daim ntawv ntawm cov rog, vim yog qhov nqus qis ntawm cov piam thaj los ntawm lub siab thaum noj cov tshuaj no.

Yog li, yuav ua li cas noj Metformin rau qhov hnyav phaus? Txhawm rau qhov tshwm sim ntawm kev noj cov tshuaj kom zoo, thiab cov ntsiav tshuaj tsis muaj kev phom sij, koj yuav tsum ua raws li cov lus qhia los ntawm cov kws kho mob.

Koj tsis tuaj yeem noj cov tshuaj no ntau tshaj 22 hnub, thiab kev noj tshuaj txhua hnub yuav tsum tsis pub tshaj 1500 mg.

Cov cai ntxiv rau kev noj cov tshuaj Metformin, kev ua raws nrog uas yuav ua rau kom poob phaus:

Thaum lub sijhawm noj cov ntsiav tshuaj, kev tawm dag zog lub zog yog yuav tsum ua,
Lub hauv paus ntawm cov khoom noj khoom haus yuav tsum yog lub teeb thiab yooj yim zom cov zaub mov,
Haus dej kom ntau
Txwv koj tus kheej kom noj.

Txhua tus paub cov khoom lag luam uas txhawb nqa nce hnyav. Hmoov nplej thiab nplej zom, mov, qos yaj ywm, nqaij rog, mov thiab dej cawv yuav tsum muaj tsawg tsawg li qhov ua tau.

Tus kws kho mob nws tus kheej tau sau ntawv noj cov tshuaj Metformin rau txhua tus neeg mob ib leeg zuj zus. Cov neeg uas tsis rog dhau los, tab sis nws nquag rog, tuaj yeem noj cov ntsiav tshuaj nrog 200 mg, thiab tus kws tshaj lij rog yuav tshaj tawm txog 1500 mg rau ib hnub.

Nws yog qhov ua tau kom poob ceeb thawj nrog kev pab ntawm Metformin, tab sis qee qhov koj yuav tau txwv koj tus kheej kom noj. Thaum lub sijhawm noj cov tshuaj, lub cev hnyav dua li qub. Cov naj npawb rau qhov hnyav tuaj yeem ncav cuag 15 kg.

Nws yuav tsum tau yug los hauv koj lub siab uas koj tuaj yeem tsis tuaj yeem yuag ntau heev hauv lub sijhawm luv luv, qhov no yog kev ntxhov siab rau lub cev, yog li 5-6 kg hauv 22 hnub yog qhov tshwm sim ib txwm muaj.

Ib yam li ib yam yeeb tshuaj twg, Metformin muaj ib tug xov tooj ntawm contraindications rau siv thiab phiv. Koj yuav tsum ua tib zoo kawm cov ntaub ntawv no ua ntej noj cov tshuaj.

Cov neeg uas muaj contraindications rau Metformin:

Cev xeeb tub thiab lactating poj niam
Nrog rau kev mob hnyav ntawm cerebrovascular,
Kev txom nyem los ntawm cov kab mob ntawm lub raum, mob siab, mob ntsws thiab lub siab,
Quav Cawv
Cov neeg mob ntshav qab zib nyob hauv lub xeev tsis nco qab lossis tus poj koob yawm txwv.

Tsis txhob hnov qab tias lub cev ntawm txhua tus neeg yog qhov tshwj xeeb thiab tuaj yeem tshwm sim qhov tsis zoo rau qhov tshuaj tsis tau paub. Hypersensitivity rau ib qho tshuaj twg yuav tshwm sim yam tsis tau xav txog, nws tsim nyog xav txog qhov no ua ntej haus cov ntsiav tshuaj yam tsis muaj kev saib xyuas mob.

Cov kev mob tshwm sim tuaj yeem mob sib khuav xwb thiab tsis hnov ntev, tab sis qee zaus tus mob no yuav siv sijhawm ntev thiab yuav tsum tau sab laj nrog kws kho mob. Thaum muaj qhov tshwm sim tsis zoo ntawm lub cev rau kev noj cov ntsiav tshuaj, koj yuav tsum tso tseg tsis noj lawv tam sim ntawd.

Xeev siab thiab ntuav
Mob plab thiab mob raws plab
Tsawg tus nqi qis lossis ua tiav tsis qab los noj mov,
Cov pob me me rau ntawm lub cev,
Saj cov hlau hauv qhov ncauj
Lactic acid coma (cov tuag taus thiab tsis tshua muaj teeb meem).

Ua ntej noj cov tshuaj Metformin, nws yog qhov yuav tsum tau qhia rau tus kws kho mob txog txhua yam teeb meem kev mob nkeeg, mob ntev thiab mob ntawm cov kws kho mob sab laj. Kev zais ntawm cov ntaub ntawv tseem ceeb no tuaj yeem ua rau muaj kev cuam tshuam txaus ntshai.

Tus nqi ntawm Metformin tej zaum yuav txawv. Hauv cov khw muag tshuaj muaj cov tshuaj uas tus nqi 50-3000 rubles. Cov kev xaiv rau ntsiav tshuaj ntawm cov tshuaj no ntau. Tus kws kho mob yuav sau ntawv muab cov tshuaj kom raug rau txhua tus neeg mob sib cais, tsom rau nws kev noj qab haus huv thiab lwm yam.

Cov tshuaj ntawm cov tshuaj muaj nyob rau txhua qhov, tab sis lawv tus nqi yog siab dua. Cov nyhuv ntawm analogues thiab Metformin yuav luag zoo ib yam, tab sis tus nqi sib txawv. Vim li cas them nyiaj ntau rau qhov tshuaj yog tias koj tuaj yeem yuav nws pheej yig dua.

Thiab ntawm no koj yuav pom cov npe tshuaj zoo cov khoom poob ceeb thawj uas tau muag hauv khw muag tshuaj. Txawm li cas los xij, ceev faj txog kev noj tshuaj; sab laj nrog koj tus kws kho mob.

Nyeem txog cov txiaj ntsig thiab kev ua phem ntawm muv subpestilence ntawm no. Nws hloov tawm tias lawv tuaj yeem kho ntau yam kabmob.

Txhua yam tshuaj tsim los kho tus mob yuav tsum tsis txhob noj rau lwm lub hom phiaj. Tib neeg lub cev ua haujlwm hauv qee lub suab nrov thiab koj tsis tuaj yeem tsoo nws yog tias koj xav poob phaus. Hnub no koj tuaj yeem nrhiav ntau cov ntaub ntawv hais txog kev poob phaus, tab sis koj tsis tuaj yeem ntseeg nws yam tsis muaj tseeb.

Ib qho ntxiv, kom poob ceeb thawj nrog kev pab ntawm Metformin, koj yuav tsum ua kom muaj kev sib zog, tsuas yog noj cov tshuaj noj yuav tsis tawm qhov hnyav, yog li vim li cas thiaj li muaj kev phom sij rau koj tus kheej yog tias nws ua tiav los tshem tawm cov phaus ntxiv lawm.

Boris Anatolyevich, tus kws kho keeb

Ua ib tus kws kho mob, Kuv ntseeg tias koj yuav tsum yuag yuag zuj zus thiab tsis tas yuav noj tshuaj. Metformin tuaj yeem pab txo kev poob phaus, tab sis muaj ntau yam tshwm sim thiab contraindications. Cov neeg, tau nyeem hauv Is Taws Nem txog qhov peev xwm ntawm Metformin los hlawv cov rog, rushed kom haus nws yam tsis tau kawm cov ntaub ntawv.

Qhov tshwm sim ntawm qhov ua rau koj lub cev raug mob ntau dua qhov tshwm sim ntawm qhov poob phaus. Thaum kawg, cov neeg uas xav kom poob ceeb thawj yuav tsum nkag siab tias qhov no tsis tuaj yeem ua tiav yog tsis muaj kev txwv zaub mov, thiab kev ua kom lub cev yog qhov tseem ceeb. Metformin tsis yog panacea rau cov neeg rog.

Cov tshuaj no tau sau rau kuv los ntawm kws kho mob, vim tias kuv cov piam thaj hauv kuv lub cev tau nce ntxiv. Kuv xav hais tias cov txiaj ntsig ntawm kev noj nws ua rau kuv xav tsis thoob. Kuv pib zoo siab, thiab tseem ceeb tshaj, Kuv rog dhau heev. Kuv poob 5 kg thiab kuv zoo siab heev. Nws yog qhov kev ntxhov siab me me uas kuv muaj teeb meem lub plab mus tas li, tab sis kuv tuaj yeem ua li cas.

Cov menyuam ntxhais, Kuv tau sim haus Metformin rau qhov poob phaus. Qhov hnyav tseem yuav luag nyob rau hauv chaw, thiab mob taub hau thiab xeev siab haunted kuv tau ntev. Kuv tsis tau noj mov, tej zaum yog vim li cas nws thiaj li tsis pab kuv.

Kuv tau raug tshuaj Metformin hauv tsev kho mob. Kuv haus nws rau ib hlis thiab tsis pom tias kuv poob li cas 8 kg. Thaum xub thawj kuv tsis to taub dab tsi tau tshwm sim, thiab tom qab ntawd kuv nyeem nws. Tej zaum kuv cov khoom noj tseem cuam tshuam nrog, kuv hloov pauv, li qab zib pib nce. Feem ntau, Kuv txaus siab txog qhov tshwm sim.

Thiab kuv tau pib haus Metformin tshwj xeeb rau kev poob phaus. Ua ntej ntawd, Kuv tau kawm txog txhua qhov kev pom zoo hauv Is Taws Nem. Kuv tau noj tshuaj rau 20 hnub, ua kev kawm paub lub cev thiab noj me ntsis khoom noj, kuv poob 9 kg thaum lub sijhawm no. Tau kawg muaj cov nyhuv, tab sis koj yuav tsum sim siv zog. Tom qab ib ntus kuv yuav rov ua dua chav kawm dua.

Kuv tau sim ntau ntsiav tshuaj noj zaub mov noj thiab kuv xav tias Metformin tsis txawv ntawm lwm qhov. Kuv haus nws txog kwv yees li ib hlis thiab tsis tau txo qhov hnyav, nws poob tsuas yog 3 kg. Kuv noj zaub mov tsis tu ncua thiab tsis ua lub cev qoj ib ce, tej zaum nws cuam tshuam.

Kuv tau xaj tshuaj metformin (Glucofage) los ntawm tus kws endocrinologist ua kom yuag thiab lub cev tsis ua haujlwm (muab cov teeb meem metabolic tsis txaus), kuj tau tawm lus pom zoo rau kev noj zaub mov kom zoo. Cov tshuaj daws cov teeb meem ntawm kev ua txhaum, thiab kuv tswj kom yuag los ntawm 9 phaus.

Metoformin 500 pib haus cawv thiab cov quav tam sim ntawd npau taws. Yog tias qhov txuas ntxiv no, nws yuav tsum raug tso tseg! Tau kawg koj yuav poob phaus nrog kev ua txhaum ntawm txoj hnyuv.

Formmetin rau qhov hnyav dua - kev txheeb xyuas - Cov ntawv qhia txog pluas noj thiab yuag poob

Cov tshuaj tiv thaiv kev rog muab los ntawm cov kws kev lag luam niaj hnub no yog ntau haiv neeg. Tab sis ntau ntawm lawv muaj ib qho tshuaj yeeb tshuaj xws li metformin. Xws li, raws nws, cov khoom lag luam hu ua Formmetin tau ua.

Hauv txoj ntsiab cai, nws tsis txawv ntau ntawm lwm cov tshuaj metformin uas muaj cov tshuaj. Tab sis tseem, kev nqis tes tiag tiag ntawm cov khoom lag luam zoo li tsim nyog paub hauv kev nthuav dav.

Tom qab ntawd nws yuav dhau los ua pom tseeb dua seb nws puas meej pem los siv nws rau qhov kev poob phaus, lossis seb nws yog qhov zoo dua los xaiv qee lwm txoj hauv kev.

Forminein rau qhov hnyav dua - cov yam ntxwv ntawm kev ua

Ua ntej tshaj plaws, nws yog ib qho tsim nyog yuav tsum nco ntsoov tias Formethine tsis yog chiv keeb tshwj xeeb los ua kom tshem tawm qhov hnyav hauv lub cev. Tab sis nws cuam tshuam qeeb ntawm cov txheej txheem ntawm kev nqus ntawm carbohydrates los ntawm cov khoom noj.

Feem ntau cov tshuaj ua rau ntawm carbohydrates ceev ceev. Raws li qhov tshwm sim, cov piam thaj hauv qab no tsawg zuj zus, thiab cov haujlwm ntawm pancreatic rov qab los rau hauv qub.

Tab sis vim li cas txhua yam no cuam tshuam nrog kev poob phaus? Qhov tseeb, qhov kev sib txuas lus ncaj qha.

Nrog kev pab ntawm Formetin, koj tuaj yeem tsim cov xwm txheej uas cov txheej txheem ntawm kev ua kom poob ceeb thawj yuav yooj yim dua thiab sai dua. Txawm hais tias koj tseem yuav tau ua qee yam ntxiv qee yam mob. Ua kom poob phaus thaum noj cov tshuaj xws li, koj yuav tsum xav txog cov hauv qab no:

yuav tau tso tseg kev siv cov khoom noj muaj suab thaj,
tej cov carbohydrates yuav tsum ua kom tsawg
Txhawm rau kom yuag, koj yuav tsum tau muab koj tus kheej lub cev ua si.
tom qab 20 hnub ua ke, lawv yuav tsum los so ib hlis.

Yog li, Formethine tsis muaj qhov tshwj xeeb tshaj yog muaj txiaj ntsig zoo. Thiab cov lus cog tseg tias nws yuav "yaj roj" tsuas yog hais ncaj ncaj xwb.

Tab sis txawm li cas los xij, nws muaj peev xwm heev kom ua tiav cov phaus poob nrog nws siv. Thiab kev tshuaj xyuas tau nthuav tawm ntawm Formmetin rau qhov poob phaus tsuas yog paub meej tias qhov kev xav no.

Nws tseem raug pom tias yog dab tsi xyov yog qhov tshwj xeeb ntawm kev siv cov ntsiav tshuaj zoo li no. Tom qab ntawd qhov txiaj ntsig ntawm lawv txais mus kawm yuav yog qhov zoo tshaj plaws.

Kev Sib Sau thiab daim ntawv ntawm kev tso tawm

Cov lus qhia rau kev siv formin qhia tau tias cov tshuaj faib rau hauv cov ntsiav tshuaj uas muaj xws li muaj pes tsawg leeg:

Dosage ntawm active tshuaj

500 mg
850 mg
1 g

croscarmellose sodium,
magnesium stearate,
nruab nrab molecular phaus povidone (polyvinylpyrrolidone).

Cov chaw muag tshuaj

Cov tshuaj Formethine yog hais txog cov kab mob hypoglycemic (biguanides). Cov ntsiav tshuaj yog npaj rau cov thawj coj hauv qhov ncauj. Cov tshuaj nquag pab txo qis kev ua haujlwm ntawm daim siab gluconeogenesis, txhim kho kev siv ntshav qabzib ntau dua, thiab nce insulin rhiab heev rau lub cev nqaij. Cov tshuaj ua kom zoo, tsis muaj qhov ua rau cov ntshav tsis haum, tsis muaj qhov cuam tshuam rau lub cev ntawm cov kua dej los ntawm cov kab mob ntawm cov txiav.

Nrog kev siv tshuaj kho, qib ntawm triglycerides thiab lipoproteins hauv cov ntshav txo qis. Formmetin muaj cov nyhuv fibrinolytic, pab ua kom qhov hnyav ntawm cov neeg mob ntshav qab zib, thiab yog siv rau qhov poob phaus. Metformin yog nqus hauv lub plab, ncav ntau qhov kev xav hauv cov ntshav tom qab 2.5 teev, yog tawm hauv lub raum.

Tsuas tshuaj thiab tswj hwm

Thawj zaug siv tshuaj kho qhov nruab nrab ntawm cov tshuaj nruab nrab 500-1000 mg / hnub. Kev noj tshuaj ntau npaum li cas thiab cov tshuaj uas yuav tsum tau tsim yuav tsum tau tsim los ntawm kws kho mob tom qab ua kev tshawb fawb, ntsuas tus neeg mob muaj mob thiab loj npaum li cas ntawm tus kab mob. Rau cov neeg laus, qhov siab tshaj plaws niaj hnub noj yog 1 g ntawm kev noj tshuaj. Yuav tsum noj cov ntsiav tshuaj tom qab noj mov.

Cov lus qhia tshwj xeeb

Thaum kho nrog Formetin, cov lus qhia tau hais kom saib xyuas lub xeev ntawm kev ua haujlwm ntawm lub raum. Nws raug nquahu kom ua qhov kev ntsuas ntshav txhawm rau txiav txim siab txog qib ntshav piam thaj thiab creatinine. Cov tshuaj tsis cuam tshuam rau lub peev xwm tsav tsheb, lub tshuab phom sij. Nrog rau kev tswj hwm tib txhij ntawm sulfonylurea derivatives, insulin, cov kev qhia tau sau tseg kom tso tseg cov kev ua ub no uas muaj kev nce siab ntxiv.

Yeeb tshuaj sib cuam tshuam

Ua ke nrog qee cov tshuaj, formin yuav ua rau tsis muaj kev tiv thaiv. Kev qhia rau kev siv tsis pom zoo kom muab cov tshuaj nrog cov tshuaj hauv qab no:

Cimetidine - ib qho tshuaj uas ua rau qeeb qeeb ntawm kev siv tshuaj metformin tawm hauv lub cev.
Chlorpromazine - Kev sib xyaw ua ke nce kev pheej hmoo ntawm kev txhim kho glycemia.
Danazole - metformin txhim kho cov nyhuv hyperglycemic ntawm cov tshuaj.
Anticoagulants (coumarin derivatives) - cov tshuaj nquag ntawm Formetin txo lawv cov hauj lwm zoo.
Cov tshuaj tiv thaiv tsis haum, cov thyroid hormones, derivatives ntawm phenothiazine, nicotinic acid, thiazide diuretics, glucagon - cov tshuaj tiv thaiv kom tsis muaj zog ntawm cov tshuaj metformin.
Acarbase, Clofibrate derivatives, sulfonylureas, non-steroidal anti-inflammatory tshuaj, angiotensin-hloov enzyme inhibitors, monoamine oxidase, β-blockers, oxytetracycline - cov tshuaj no ua rau muaj kev cuam tshuam ntawm formin.
Antipsychotics - yog tias tsim nyog, ib qho kev sib xyaw ua ke yuav tsum tau muab tshuaj ntau dua ntawm metformin.

Phiv thiab haus tshaj

Yog tias cov koob tshuaj ntawm cov tshuaj qhia hauv cov lus qhia yog dhau, tus neeg mob yuav tsim muaj cov kab mob lactic acidosis. Qhov tsis muaj kev kho kom txaus ua rau tuag. Noj tshuaj yuav ua rau muaj kev phiv. Nrog rau cov tsos mob hnyav, cov kws kho mob tau sau ntawv tshuaj antispasmodics, antacids. Raws li cov lus qhia rau kev siv, muaj kev pheej hmoo:

xeev siab, ntuav,
txo los sis tsis qab los noj mov,
daim tawv nqaij ua pob
mob plab, pom pob,
zawv plab
anemia
ntshav qab zib,
lactic acidosis,
hypovitaminosis B12.

Cov Yuav Tsum Tau Ua

Cov lus qhia rau kev siv Formetin sau ntawv yuav cais tawm ntawm kev siv tshuaj 2 hnub ua ntej thiab tom qab siv hluav taws xob xoo hluav taws xob lossis xoo hluav taws xob. Koj tsis tuaj yeem sau cov tshuaj rau cov neeg laus 60 xyoo uas ua haujlwm lub cev hnyav. Formmetin muaj ib tug xov tooj ntawm lwm cov contraindications:

cev xeeb tub thiab lactation
kev haus cawv ntev dhau mus, cawv lom,
tshuaj mob ntsws
lub cev tsis haum rau cov khoom lag luam,
cov khoom noj tsis muaj calorie tsawg
kev ua haujlwm ntawm lub siab, ob lub raum,
insulin txoj kev kho tom qab raug mob, pab kev phais mob,
mob ketoacidosis,
cov kab mob ntawm ib qho kev sib kis uas ua rau cov nqaij mos hypoxia (mob plawv, ua pa tsis ua haujlwm, myocardial infarction), lub raum tsis ua haujlwm (sepsis, poob siab, hypoxia, kub taub hau, lub cev qhuav dej),
mob ntshav qab zib coma, precoma.

Kev lag luam kws tshuaj tau tsim cov tshuaj uas zoo sib xws thiab muaj cov nyhuv rau hauv formin. Cov qauv ntawm cov tshuaj yog:

Leej twg xav kom noj thiab thaum cov tshuaj yog contraindicated

Formmetin tau tsim los tswj hom mob ntshav qab zib hom 2. Nws ua tiav cov tshuaj insulin nyob rau hauv kev kho mob sib xyaw, tuaj yeem siv rau kev kho mob monotherapy yog tias kev hloov kho hauv lub neej (noj cov zaub mov qis, ua kom lub cev zoo) tsis muab qhov kev cia siab tshwm sim.

Kev txiav txim los ntawm kev txheeb xyuas, formatein rau kev poob phaus yog qhia rau hauv android hom kev rog rog ntawm tus neeg mob ntshav qab zib nrog hom mob thib ob, thaum cov rog ua rau thaj chaw hauv plab, feem ntau hauv plab.

Kev siv tshuaj kho mob kom kho qhov luaj li neeg noj qab haus huv yog qhov txaus ntshai.

Tsis txhob siv cov tshuaj:

Nrog rau qhov ua kom tsis haum rau cov khoom siv ntawm lub mis,
Yog tias qhov kev pheej hmoo ntawm cov kab mob lactic acidosis yog tus siab,
Nrog rau daim siab ua rau lub siab ua haujlwm siab,
Thaum muaj cawv qaug cawv thiab keeb kwm kev haus cawv,
Yog tias muaj concomitant loj sib kis kab mob,
Yog tias tus mob ntshav qab zib nyob rau ntawm tus tshaib plab plab (txog 1000 kcal / hnub),
Nrog ketoacidosis,
Hauv lub raum thiab cov kab mob hauv lub raum,
Yog tus neeg raug tsim txom tsis nco qab los yog qhov mob ua ntej nws,
Thaum muaj keeb kwm ntawm cov hlab plawv, qhov kev ua txhaum ntawm cerebral ntshav txaus.

Nrog kev kub nyhiab, ua rau raug mob hnyav, ua ntej thiab tom qab kev khiav haujlwm, tus neeg mob tseem raug xa mus rau cov tshuaj insulin. Yog tias ib lub cim iodine-raws li tau teem tseg rau mob ntshav qab zib, 2 hnub ua ntej thiab 3 hnub tom qab kuaj, Formmetin thim tawm.

Nrog rau cov kev txwv, lawv siv Formetin rau cov neeg muaj hnub nyoog 65 xyoos, txij li ob lub raum thiab lwm yam hauv cov neeg mob ntshav qab zib nrog cov laus tsis nyob hauv txoj kev mob zoo, thiab qhov kev pheej hmoo ntawm lactic acidosis nce.

Phiv thiab haus tshaj

Kev txiav txim los ntawm kev tshuaj xyuas ntawm cov ntsiab lus sib tham, formimetin diabetics tiv taus ib txwm. Txawm li cas los xij, kev qhia muaj ib tug xov tooj ntawm cov qhia ntawm yuav tshwm sim nyob rau hauv cov ntaub ntawv ntawm overdose los yog tus yam ntxwv ntawm lub cev.

Lub plab zom mov. Qee lub sijhawm (hauv 3% ntawm tus neeg mob) mob plab tsis ua haujlwm, ua txhaum ntawm lub suab tawm ntawm lub cev ntawm txoj kev tso quav, tsis qab los noj mov, thiab mob hauv lub epigastrium yog kaw.
Kev ua xua Cov kev tawm tsam yog ua kom pom kev ua pob (txhais tes, hauv siab, lub puab tsaig), khaus thiab nce ntawm daim tawv. Muaj qee zaus, kub taub hau yuav ua tau.
Endocrine system. Kev mob ntshav qab zib tshwm sim thaum muaj qhov tsis sib luag ntawm lwm cov tshuaj uas ua kom muaj peev xwm ntawm metformin, nrog rau kev hloov pauv ntawm cov tshuaj thiab cov tshuaj ntawm formin.
Kev zom zaub mov. Hauv cov xwm txheej huab, lactic acidosis raug pom - qhov xwm txheej txaus ntshai uas yuav tsum muaj kev tshem tawm yeeb tshuaj tam sim ntawd thiab kev kho mob tshwj xeeb.
Nrog lub sijhawm ntev ntawm kev siv cov metformin, nws nqus tau zuj zus, qhov no cuam tshuam cov ntsiab lus ntawm cov vitamins B12 (ib qho kev siv ntau tshaj yog ua tau).
Kev kaw lus hauv lub cev. Muaj tsawg (tsawg) ntu kev mob ntshav ntawm megaloblastic anemia.

Raws li kev txheeb cais, cov kev mob tshwm sim feem ntau tshwm sim thaum pib ntawm kev kho, kom txog thaum lub cev tau yoog raws li cov xwm txheej tshiab. Nrog kev siv tsis tu ncua tom qab ib hlis, feem ntau cov tsos mob ploj yam tsis kho ntawm kev kho mob kiag. Nrog rau cov kev mob tshwm sim loj heev, kws kho mob tuaj yeem sau tshuaj antispasmodic lossis antacid.

Yog tias koj huam yuaj lossis txhob txwm nce qib ntau zaus, qhov tshwm sim tuaj yeem yog qhov tseem ceeb (txog thaum tuag). Lactic acidosis tuaj yeem tshwm sim yog tias ntau npaum li cas tau pom, yog tias lub raum tsis lees ua cov tshuaj metabolites hauv lub sijhawm.

Thawj cov tsos mob ntawm tus kab mob lactic acidosis:

Kev mob ntshav siab heev,
Neej Hmoob
Ua npaws lossis ua daus no
Lub plawv dhia qeeb
Tsis muaj kev sib koom tes
Txog siav
Mob qab zib coma.

Yog tias muaj txawm tias ob peb yam ntawm cov tsos mob tau teev tseg, kev siv cov tshuaj raug tso tseg, tus neeg raug tsim txom tau muab cov khoom nqus tau tso txoj hnyuv tawm ntawm cov tshuaj tsis tau ua tiav, thiab lawv hu rau kev pab kho mob. Thaum mus pw hauv tsev kho mob, kho mob hemodialysis, kev kho mob yam ntxwv yog yam tshuaj.

Qhia Txog Tshuaj Yeeb

Formmetin yog ib qho tshuaj kho mob thoob plaws ntiaj teb: nws tuaj yeem siv rau kev kho mob monotherapy lossis txuas nrog rau lwm cov tshuaj hypoglycemic, suav nrog cov tshuaj insulin.

Tab sis qee qhov xwm txheej, hauv kev kho cov kab mob concomitant, kev kho nyuaj tuaj yeem muaj cov nyom zoo.

Nrog rau kev tswj hwm tib lub sijhawm ntawm Danazol, nws muaj kev pheej hmoo ntawm lub qog ntshav qab zib, yog li cov tshuaj ntawm cov tshuaj yuav tsum raug tswj hwm nruj lossis hloov nrog ib qho analog.
Thaum ua ke nrog cimetidine, qhov kev nthuav tawm ntawm metformin yog inhibited, nws cov tsub zuj zuj hauv lub cev tuaj yeem muab cov nyhuv uas tsis tuaj yeem tswj tau hypoglycemic.
Muaj peev xwm ua tau ntawm cov khoom coj tuaj muag yog tshuaj tiv thaiv los ntawm metformin.
Ua ke nrog kev kho mob nrog carbazole, NSAIDs, clofibrate, insulin, ACE inhibitors, cytophosphamide, β-blockers, sulfonylureas, oxytetracycline txhim kho cov kev ua ntawm metformin.
Cov thawj coj ua ke ntawm glucagon, epinephrine, thiazide diuretics, cov thyroid hormones tiv thaiv kev ua haujlwm ntawm formin.

Thaum siv tshuaj tiv thaiv qhov ncauj, tus poj niam yuav tsum ceeb toom cov hom tshuaj mus rau endocrinologist kom kho qhov koob ntawm Formetin. Tsis txhob sau nws thiab ua ke nrog Nifedipine, uas nce qib ntawm cov metformin hauv cov hlab ntshav, ua kom nrawm nws qhov nqus, txo kev tshem tawm. Yog tias muaj teeb meem nrog lub raum, cov txiaj ntsig zoo li no tuaj yeem ua rau tus neeg tsis xeev rov qab.

Yog tias cov tshuaj ua rau lub hauv paus ntawm ethyl cawv, ua ke nrog metformin, qhov kev pheej hmoo ntawm mob lactic acid nce ntau.

Formmetin - analogues

Hauv pawg (cov tshuaj tiv thaiv kab mob hauv qhov ncauj) thiab cov tshuaj tiv thaiv (metformin hydrochloride), cov tshuaj hauv qab no sib luag: Metamine, Bagomet, NovoFormin, Formin.

Raws li cov tshuaj muaj peev xwm ntawm Formetin zoo sib xws:

Lymphomyozot,
Qhuas Tub Ntxawg,
Pioglar
Levemir Flekspen,
Levemir Penfill,
Av ‡ Q

Cov kev xaiv ntawm lwm cov kua qab zib qis hauv kev lag luam tshuaj muaj peev xwm loj heev, txawm tias tus kws tshaj lij tshwj xeeb yog qhov nyuaj rau kev nkag mus hauv cov kev tawm tsam no. Zoo, thiab cov ntshav qab zib kom sim nrog lawv txoj kev noj qab haus huv ntau dua. Yog li, koj yuav tsum tsis txhob tso siab rau lub tswv yim ntawm cov neeg nyob ze lossis kev tshaj tawm hauv cov teeb meem no. Tsuas yog tus kws kho mob yuav xaiv qhov kev hloov pauv zoo, suav nrog qhov hnyav ntawm tus kab mob thiab kev noj qab haus huv feem ntau.

Cov Ntshav Qab Zib Cov Lus Qhia ntawm Formetin

Txog Formin, kev ntsuam xyuas ntawm tus mob ntshav qab zib yog sib xyaw. Cov neeg uas noj tshuaj ntev, nco txog nws cov txiaj ntsig zoo. Cov pib yws txog kev phiv. Dyspeptic mob ploj mus ntawm lawv tus kheej tom qab ob peb lub lis piam, yog tias koj tsis sim nrog kev teem caij ntawm tus kws kho mob. Txawm hais tias lub hnub nyoog txwv nyob rau hauv cov lus qhia yuav tsum tau coj mus rau hauv tus account.

Formformin-based metformin yog tshuaj hauv tsev muaj cov ntawv pov thawj loj. Feem ntau, tshwj xeeb tshaj yog muaj ntshav qab zib hom 2, tsuas yog tsis muaj lwm txoj kev xaiv rau metformin derivatives. Yog li, tsis txhob maj maj rau cov lus xaus hais txog nws cov txiaj ntsig, nws yog qhov zoo dua los pab lub cev hloov mus rau kev noj tshuaj tshiab nrog kev pab los ntawm kev noj zaub mov, kev coj tus cwj pwm kom zoo rau kev kho mob thiab cov kev tawm dag zog kom haum rau kev noj qab haus huv. Yog tias tsis muaj txoj hauv kev no, tshuaj tshiab tshaj plaws yuav tsis muaj qab hau.