Ciprolet® (250 mg) Ciprofloxacin

• zaj duab xis-ntsiav tshuaj: puag ncig biconvex, nrog rau ib qhov chaw du, lub plhaub thiab lub hauv paus ntawm cov ntsiav tshuaj yuav luag tag nrho cov xim dawb lossis dawb (10 daim ib leeg, hauv daim duab los qhwv 1 lossis 2 blisters),
• Txoj kev daws teeb meem: tsis muaj kob lossis lub teeb daj ua kua dej (100 ml txhua lub raj mis yas, 1 lub raj mis hauv ib pob ntawv ntawv)
• qhov muag tso tawm: ntshiab lub teeb daj lossis xim tsis muaj kua (5 ml txhua tus hauv lub raj mis yas dropper, 1 lub raj mis hauv pob ntawv yas).

1 ntsiav tshuaj muaj:

• cov tshuaj nquag: ciprofloxacin hydrochloride - 291.106 mg lossis 582.211 mg, uas yog sib npaug nrog cov ntsiab lus ntawm 250 mg lossis 500 mg ntawm ciprofloxacin (feem),
• Cov khoom siv pabcuam: croscarmellose sodium, cov hmoov txhuv nplej pob kws, colloidal silicon dioxide, microcrystalline cellulose, magnesium stearate, talc,
• lub plhaub muaj pes tsawg leeg: sorbic acid, hypromellose (6 cps), macrogol 6000, polysorbate 80, titanium dioxide, dimethicone, talc.

1 ml ntawm cov tshuaj muaj:

• cov tshuaj nquag: ciprofloxacin - 2 mg,
• Cov khoom siv pabcuam: hydrochloric acid, sodium chloride, lactic acid, disodium edetate, sodium hydroxide, citric acid monohydrate, dej rau kev txhaj tshuaj.

1 ml tee muaj:

• cov tshuaj nquag: ciprofloxacin hydrochloride - 3.49 mg, uas yog sib npaug nrog cov ntsiab lus ntawm 3 mg ntawm ciprofloxacin,
• Lub cev ntu: disodium edetate, 50% kev daws teeb meem ntawm benzalkonium chloride, hydrochloric acid, sodium chloride, dej rau kev txhaj tshuaj.

Zaj duab xis-coated ntsiav tshuaj thiab infusion daws

Kev siv Ciprolet nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj thiab kev daws yog qhia rau kev kho mob kis mob thiab mob los ntawm cov kab mob me me nkag siab ciprofloxacin, suav nrog:

• kis kab mob ntawm cov hniav, lub qhov ncauj, lub puab tsaig, lub plab zom mov,
• mob ntawm lub pob ntseg, qhov ntswg thiab caj pas,
• ua pa ntawm kab mob
• gallbladder thiab biliary huam mob,
• mob raum thiab mob txeeb zig
• musculoskeletal mob,
• kev kis tus mob ntawm cov qog ua kua, tawv nqaij thiab cov nqaij mos,
• tom qab kis tas
• mob kis ntawm chaw mos (prostatitis, gonorrhea, adnexitis),
• sepsis
• mob peritonitis.

Tsis tas li ntawd, cov ntsiav tshuaj thiab cov tshuaj daws tau siv yog ib feem ntawm txoj kev kho mob nyuaj nrog cov tshuaj tiv thaiv kab mob hauv kev tiv thaiv thiab kho mob ntawm cov mob hauv cov neeg mob uas txo qis kev tiv thaiv.

Qhov muag tee

Kev siv cov tee yog qhia rau kev kho mob ntawm kev sib kis thiab cov kab mob ntawm lub qhov muag thiab nws cov lus qhib tshwm sim los ntawm cov kab mob uas nkag siab cov tshuaj:

• subacute thiab mob pob txha caj qaum,
• blepharoconjunctivitis, blepharitis,
• corneal mob rwj ntawm cov kab mob etiology,
• keratoconjunctivitis, kab mob keratitis,
• mob ntev ntawm meibomite thiab dacryocystitis,
• kis mob hnyav tom qab kev phais mob,
• kis tau yooj yim tom qab raug mob rau lub qhov muag lossis lub cev txawv teb chaws nkag mus (nrog rau kev tiv thaiv).

Tsis tas li ntawd, tee raug siv hauv ophthalmic phais rau kev tiv thaiv kev ntxhov siab.

Cov Yuav Tsum Tau Ua

• lub caij nyoog ntawm cev xeeb tub thiab pub niam mis,
• tus kheej tsis kam txais fluoroquinolone pab pawg npaj,
• ua kom lub cev tsis haum rau cov tshuaj ntawm cov tshuaj.

Nrog kev ceev faj, Cyprolet yuav tsum tau siv rau kev mob hlwb, mob hlwb tsis ua haujlwm, mob tuag tes tuag taw.

Ntxiv rau, cais cov contraindications rau txhua daim ntawv tshuaj noj.

Txoj kev lis ntshav daws

Kev daws yog npaj rau kev ua dej num (iv) nrog kev tswj hwm.

Txoj kev daws teeb meem tuaj yeem tov nrog 0.9% sodium chloride tov, 10% kev daws teeb meem fructose, 5% thiab 10% dextrose daws, Ringer txoj kev daws teeb meem, tov nrog 5% dextrose tov thiab 0.225% lossis 0.45% sodium chloride tov.

Thaum kws kho mob muab koob tshuaj, cov cim kev kuaj mob, hom kev kis tus mob, mob, hnub nyoog thiab qhov hnyav ntawm tus neeg mob, cov kab mob sib cuam tshuam yuav tsum ua tib zoo xav.

Lub sijhawm ntawm infusion yuav tsum nyob ntawm tus nqi ntawm 0.5 teev rau kev qhia ntawm 200 mg ntawm cov tshuaj.

Cov tshuaj pom zoo: cov mob me ntsis - 200 mg 2 zaug ib zaug khob, hnyav - 400 mg 2 zaug ib hnub. Lub sijhawm kho yog 7-14 hnub lossis ntau dua.

Hauv kev mob gonorrhea, tus neeg mob tau sau ntawv 100 mg ib zaug.

Kev tiv thaiv ntawm kev mob postoperative yog nqa tawm los ntawm kev tswj 200-400 mg ntawm yeeb tshuaj 0.5-1 teev ua ntej kev phais mob.

Cov lus qhia tshwj xeeb

Vim txoj kev pheej hmoo ntawm kev phiv los ntawm lub hauv nruab nrab lub paj hlwb, cov neeg mob uas muaj keeb kwm ntawm qaug dab peg, qaug dab peg, mob hlwb rau lub hlwb, thiab cov kab mob vascular pathologies tuaj yeem kho Ziprolet ib leeg rau kev mob nkeeg.

Yog tias mob raws plab thiab mob ntev ua rau pom tshwm sim thaum kho, nws yog qhov tsim nyog kom tshem tawm qhov muaj pseudomembranous mob plab, yog tias kev pom tseeb ntawm kev kuaj mob, tshem tawm cov ntsiav tshuaj sai thiab daws tau.

Vim tias qhov tshwm sim ntawm txoj kev mob ntawm txoj leeg nqaij lossis pob txha caj dab vim yog siv cov ntsiav tshuaj thiab daws cov tshuaj, kev kho mob yuav tsum tsis ua haujlwm ntxiv thaum thawj cov tsos mob ntawm tus mob tendovaginitis lossis mob hauv cov leeg tau tshwm sim.

Kev siv tshuaj ntawm qhov ncauj thiab niam txiv yuav tsum tau nrog cov kua hauv lub cev txaus rau cov neeg mob uas muaj diuresis ib txwm.

Thaum kho, nws pom zoo kom zam lub hnub ncaj qha.

Tsis txhob coj iav lo ntsiab muag thaum siv tee.

Cov tshuaj rau qhov muag tsis tuaj yeem raug txhaj rau hauv chav txuas sab xub ntiag ntawm lub qhov muag lossis subconjunctivally.

Nrog rau kev siv rau lwm qhov kev daws teeb meem ophthalmic, kev so ntawm cov txheej txheem yuav tsum yog 5 lossis ntau feeb.

Kev siv Tsiprolet muaj qhov tsis zoo rau tus neeg mob lub peev xwm los tsav lub tsheb thiab cov twj.

Yeeb tshuaj sib cuam tshuam

Nrog tib lub sijhawm siv Cyprolet:

• didanosine txo qhov nqus ntawm ciprofloxacin,
• theophylline tuaj yeem nce ntshav plasma concentration thiab qhov kev pheej hmoo ntawm kev txhim kho nws cov nyhuv ua rau mob lom,
• cov tshuaj muaj txhuas, zinc, hlau lossis magnesium ions, thiab antacids tuaj yeem txo qhov nqus ntawm ciprofloxacin, yog li lub sijhawm nruab nrab ntawm kev noj cov tshuaj no yuav tsum yog tsawg kawg 4 teev,
• cyclosporin txhim kho nws cov nyhuv nephrotoxic,
• lwm cov tshuaj tua kab mob (aminoglycosides, beta-lactams, clindamycin, metronidazole) ua rau cov nyhuv synergistic,
• cov tshuaj uas tsis yog tshuaj steroidal (tshwj tsis yog acetylsalicylic acid) ua rau kom muaj kev pheej hmoo ntawm cov qaug dab peg,
• metoclopramide nrawm mus rau kev nqus ntawm ciprofloxacin,
• uricosuric cov neeg sawv cev ntxiv ua kom ntshav muaj peev xwm ntawm ciprofloxacin,
• qhov ua tsis ncaj rau cov tshuaj tiv thaiv txhim kho lawv cov nyhuv, ua kom ntev dua lub sijhawm los ntshav.

Pom zoo kom sib xyaw rau kev kho qee yam kab mob:

• muaj mob los ntawm Pseudomonas spp: azlocillin, ceftazidime,
• cov kab mob streptococcal: meslocillin, azlocillin thiab lwm yam tshuaj tua kab mob beta-lactam,
• mob staph: isoxazolylpenicillins, vancomycin,
• cov kab mob anaerobic: metronidazole, clindamycin.

Lub acidity (pH) ntawm ciprofloxacin infusion daws yog 3.5-4.6; yog li ntawd, nws yog pharmaceutically incompatible nrog tsis ruaj khov infusion daws thiab kev npaj. Rau kev tswj hwm iv, nws tsis tuaj yeem tov nrog kev daws teeb meem nrog pH ntau dua 7.

Cov qauv ntawm Ciprolet yog: cov ntsiav tshuaj - Ciprofloxacin, Cifran, Ciprinol, Ciprobay, cov kev daws teeb meem - Ififpro, Ciprobid, Quintor, tee - Cipromed, Rocip, Ciprofloxacin-AKOS.

Ntsiav tshuaj thiab kev daws rau Txoj kev lis ntshav

Kev kis mob thiab mob kis los ntawm cov kab mob me me uas rhiab rau ciprofloxacin.

• cov kab mob ua pa tsawg dua (mob ntsws, mob ntsws, mob ntsws, mob ntsws thiab ua rau mob ntsws txhaws ntev, mob sib kis ntawm cystic fibrosis),
• Cov mob ENT (mob ntsws mob sai),
• mob ntawm lub raum thiab mob txeeb zig (cystitis, pyelonephritis),
• muaj mob kis ntawm qhov chaw mos
• cov kab mob kis tau ntawm lub plab (kab mob hauv plab, lub plab zom mov),
• kis kab mob ntawm cov tawv nqaij thiab cov nqaij mos: mob txhab, mob, kub hnyiab, ua npaws, phlegmon,
• muaj mob los ntawm kev tiv thaiv kab mob thaum noj tshuaj tiv thaiv kab mob, nrog rau cov neeg mob neutropenia,
• sepsis
• mob peritonitis
• kis kab mob ntawm cov pob txha thiab pob qij txha: mob caj dab mob txha caj qaum, txha osteomyelitis,
• kev tiv thaiv thiab kho mob ntsig txog mob ntsws anthrax.

Cov menyuam yaus hnub nyoog 5 txog 17 xyoo:

• kev kho mob ntawm kev mob tshwm sim los ntawm Pseudomonasaeruginosa hauv cov menyuam yaus mob ntsws ntsig,
• kev tiv thaiv thiab kho mob ntsig txog mob ntsws ntsws (Bacillusanthracis).

Tsis tas li ntawd, rau kev daws teeb meem: ua mob hnyav rau hauv plab (ua ke nrog metronidazole), nrog rau tus mob shigellosis, tus neeg mus ncig ua si raws plab, mob ntsws, peritonitis, campylobacteriosis, tiv thaiv kev kis kab mob thaum kev phais mob.

Qhov muag tee

Kev kis tus kab mob ntawm lub qhov muag thiab nws cov tshwm sim los ntawm cov kab mob me me nkag siab rau cov tshuaj:

• mob sib xws thiab subacute conjunctivitis,
• blepharoconjunctivitis,
• blepharitis
• cov mob txhab ua pob rau lub ntsej muag,
• cov kab mob keratitis thiab keratoconjunctivitis,
• mob dacryocystitis thiab mob meibomites.

Kev tiv thaiv thiab kho kab mob sib kis mob tom qab kev phais mob, raug mob, txawv teb chaws lub cev.

Dosage daim ntawv

Coated ntsiav tshuaj, 250 mg, 500 mg

Ib ntsiav tshuaj muaj

cov tshuaj heev - ciprofloxacin 250 mg lossis 500 mg,

zam txim: pob kws hmoov txhuv nplej siab, microcrystalline cellulose, croscarmellose sodium, colloidal silicon dioxide, purified talc, magnesium stearate,

plhaub muaj pes tsawg leeg: hypromellose, sorbic acid, titanium dioxide, lim talc, macrogol (6000), polysorbate 80, dimethicone.

Cov ntsiav tshuaj dawb yog qhov puag ncig, nrog qhov chaw biconvex thiab du rau ob sab, nrog qhov siab (4.10  0.20) mm thiab lub cheeb (11.30  0.20) mm (rau qhov ntau npaum li 250 mg) lossis qhov siab (5.50  0.20) mm thiab lub cheeb ( 12.60  0.20) mm (rau qhov tau ntau npaum 500 mg).

Cov chaw muag tshuaj

Cov Tshuaj Pharmacokinetics

Sai sai nqus los ntawm kev mob plab zom mov. Txoj kev ntsuam xyuas kev nyab xeeb tau tom qab tswj hwm ntawm qhov ncauj yog 70%. Noj khoom ib nyuag qhov cuam tshuam kev nqus ntawm ciprofloxacin. Lub plasma profile ntawm qhov kev txiav txim siab ntawm ciprofloxacin rau kev tswj hwm qhov ncauj yog zoo ib yam li ntawd rau kev tswj hwm kev tso ntshav, yog li ntawd, qhov ncauj ntawm txoj kev nkag thiab txoj haujlwm ntawm kev tswj hwm tuaj yeem txiav txim siab hloov pauv. Kev sib txuas lus nrog cov protein ntshav yog 20 - 40%. Qhov kev tshem tawm ib nrab ntawm lub neej ntawm ciprofloxacin yog 6 mus rau 8 teev tom qab ib koob lossis ntau koob. Ciprofloxacin nkag mus rau hauv cov plab hnyuv siab raum thiab cov ntaub so ntswg: lub ntsws, hnoos qeev ntawm lub ntsws thiab hnoos qeev, cov kab mob ntawm cov genitourinary system, nrog rau cov qog ua kua rau lub caj pas, cov leeg pob txha, kua dej ua kua, polymorphonuclear leukocytes, alveolar macrophages. Nws yog faib tsuas yog nrog tso zis thiab kua tsib.

Cov Tshuaj Hauv Tshuaj

Ciprolet® yog ib qho tshuaj tua kab mob ntau los ntawm pab pawg ntawm fluoroquinolones. Txhawb kev tiv thaiv cov kab mob DNA gyrase (topoismerases II thiab IV, lub luag haujlwm ntawm cov txheej txheem ntawm supercoiling ntawm chromosomal DNA nyob ib ncig ntawm nuclear RNA, uas tsim nyog rau kev nyeem cov ntaub ntawv keeb kwm), cuam tshuam DNA synthesis, kab mob loj hlob thiab faib, ua rau muaj kev hloov morphological (suav nrog cov xovtooj ntawm tes thiab daim nyias nyias) thiab kev tuag sai sai ntawm ib tus kab mob cell. Nws ua rau gram-negative microorganisms thaum dormancy bacteriostatically thiab thaum lub sijhawm faib division bactericidal (vim nws cuam tshuam tsis tsuas DNA gyrase, tab sis kuj ua rau lysis ntawm lub cell phab ntsa), thiab ntawm gram-positive microorganisms nws yog bactericidal tsuas yog thaum lub sijhawm faib. Tsis tshua muaj tshuaj lom rau macroorganism hlwb tau piav qhia los ntawm qhov tsis muaj DNA gyrase hauv lawv. Ciprolet® ua rau tawm tsam feem ntau ntawm cov kab mob me me hauvvitro thiab hauvvivo:

- aerobic gram-cov kab mob zoo: Corynebacterium diphtheriae, Enterococcus faecalis, Listeria monocytogenes, Staphylococcus spp., Suav nrog Staphylococcus aureus, epidermidis, Streptococcus pyogenes, agalactiae, pneumoniae, Streptococcus (pawg C, G), Viridans pawg

- aerobic gram-cov kab mob tsis zoo: Acinetobacter spp. Xws li Acinetobacter anitratus, baumannii, calcoaceticus, Actinobacillus actinomycetemcomitans, Bordetella pertussis, Citrobacter freundii, ua yeeb yam, Enterobacter spp. parainfluenzae, Helicobacter pylori, Klebsiella spp., suav nrog Klebsiella oxytoca, pneumoniae, Moraxella catarrhalis, Morganella morganii, Neisseria gonorrhoeae, Neisseria meningitides, suav nrog Pasteurella canis, mob ntsws, mondiais, priaisisisis, muv, thiab lwm yam. Salmonella spp., Serratia spp., Suav nrog Serratia marcescens,

- anaerobic microorganisms: Bifidobacterium spp., Clostridium perfringens, Fusobacterium spp., Peptostreptococcus, Propionibacterium spp., Veillonella spp.,

- intracellular microorganisms: Tus kab mob Streptococcus pneumoniae, Enterococcus faecalis, Chlamydia pneumoniae, psittaci, trachomatis, Legionella spp., Suav nrog Legionella pneumophila, Mycobacterium spp., Suav nrog Mycobacterium leprae, mob ntsws, Mycoplasma pneumoniae, Rickettsia spp.

Ciprolet® tiv taus Ureaplasma urealyticum, Clostridium difficile, Nocardia asteroids, Bacteroides fragilis, Pseudomonas cepatica, Pseudomonas maltophilia, Treponema pallidum

Kev ntsuas rau siv

Kev kis tsis yooj yim thiab mob uas cuam tshuam los ntawm cov kab mob me me rau ciprofloxacin:

- kis kab mob ntawm ENT kabmob (otitis media, sinusitis, frontal sinusitis, mastoiditis, tonsillitis)

- kis mob ntawm cov pa hauv qis ua rau muaj cov kab mob gram-tsis zoo tshwm sim los ntawm Klebsiella spp., Enterobacter spp., Proteus spp., Esherichia coli, Pseudomonas spp., Haemophilus spp., Branhamella spp., legionella spp., Staphylococcus spp. (exacerbation ntawm mob ntsws ob leeg nyob rau hauv lub ntsws, mob ntsws bronchopulmonary nrog rau cystic fibrosis lossis bronchiectasis, mob ntsws)

- mob txeeb zig (mob los ntawm tus kab mob gonococcus mob thiab mob ncauj tsev menyuam)

- cov kab mob sib kis los ntawm kev sib deev uas tau muaj Neisseriagonorrhoeae (kab mob gonorrhea, chancre me me, urogenital chlamydia)

- Kev mob sib kis mob ntsws, nrog rau cov mob tshwm sim los ntawm Neisseriagonorrhoeae.

- mob ntawm lub plab hu ua pelvic plab hnyuv siab raum nyob rau hauv cov poj niam (mob kab mob ntawm lub plab hu ua), suav nrog cov mob los ntawm Neisseria gonorrhoeae

- mob plab (kab mob ua rau lub plab zom mov lossis mob hnyuv, mob peritonitis)

- kis ntawm daim tawv nqaij, cov nqaij mos

- septicemia, bacteremia, kev kis kab mob lossis kev tiv thaiv kab mob hauv cov neeg mob uas lub cev tsis muaj zog tiv thaiv kab mob (piv txwv, hauv cov neeg mob noj tshuaj tiv thaiv kab mob lossis nrog neuropenia)

- kev tiv thaiv thiab kho mob ntsig txog mob ntsws (mob Bacillus anthracis)

- kis kab mob ntawm cov pob txha thiab pob qij txha

Menyuam yaus thiab tub ntxhais hluas

- Hauv kev kho mob ntawm kev mob tshwm sim los ntawm Pseudomonas aeruginosa hauv cov menyuam yaus hnub nyoog qis dua 6 xyoo nrog cystic fibrosis

- ua mob hnyav ntawm mob txeeb zig thiab pyelonifrita

- kev tiv thaiv thiab kho mob ntsig txog mob ntsws (mob Bacillus anthracis)

Tsuas tshuaj thiab tswj hwm

Ciprolet® ntsiav tshuaj tau muab rau cov neeg laus noj ntawm qhov ncauj, ua ntej noj mov lossis nruab nrab ntawm cov pluas noj, tsis tas yuav zom, haus dej kom ntau. Thaum noj rau ntawm lub plab tas, cov tshuaj nquag yuav nqus sai dua. Ciprofloxacin ntsiav tshuaj yuav tsum tsis txhob noj nrog cov khoom noj siv mis (piv txwv, mis, kua mis nyeem qaub) lossis kua txiv hmab txiv ntoo nrog qhov sib ntxiv ntawm cov zaub mov.

Cov koob tshuaj tau txiav txim siab ntawm qhov xwm txheej thiab qhov mob hnyav, nrog rau qhov rhiab ntawm cov kab mob tsis txaus ntseeg, tus neeg mob lub raum kev ua haujlwm, thiab hauv cov menyuam yaus thiab cov hluas, tus neeg mob lub cev qhov hnyav tau raug suav.

Qhov koob tshuaj tau txiav txim siab raws li kev qhia, hom thiab mob hnyav ntawm tus kabmob, mob rhiab rau ciprofloxacin, kev kho mob yog nyob ntawm qhov mob hnyav, nrog rau kev kuaj mob thiab cov kab mob.

Hauv kev kho mob kis mob los ntawm qee cov kab mob (e.g.,Pseudomonas aeruginosa, Acinetobacter lossis Qhatafilococ) Kev txhaj tshuaj ntau dua ntawm ciprofloxacin yog qhov yuav tsum tau ua thiab tuaj yeem txuas nrog ib lossis ntau dua lwm cov tshuaj tiv thaiv kabmob.

Hauv kev kho qee yam mob (piv txwv li, mob pelvic inflammatory rau cov poj niam, mob plab, mob sib kis hauv cov neeg mob neutropenia, mob sib kis ntawm cov pob txha thiab pob qij txha), kev sib xyaw ntawm ib lossis ntau cov tshuaj tua kab mob sib kis tau, nyob ntawm cov kab mob pathogenic uas ua rau lawv. Cov tshuaj yog pom zoo nyob rau hauv cov koob tshuaj hauv qab no:

Cov Khoom Qhia

Mg noj txhua hnub

Ntev ntawm tag nrho kev kho mob (suav nrog kev pib kho mob kho mob nrog kho nrog ciprofloxacin)

Tsawg kis kab mob

2 x 500 mg rau

7 txog 14 hnub

Sab saud mob ntsws

Exacerbation ntawm kev mob caj dab ntev

2 x 500mg rau

7 txog 14 hnub

Ntev li mob otitis media

2 x 500mg rau

7 txog 14 hnub

Malignant otitis sab nraud

Txij li 28 hnub txog 3 hlis

Mob txeeb zig

2 x 500mg txog 2 x 750mg

cov poj niam thaum lub cev ntas - ib zaug 500 mg

Mob cystitis, mob tsis yooj yim rau pyelonephritis

2 x 500mg txog 2 x 750mg

Tsawg kawg 10 hnub nyob hauv qee kis (piv txwv, muaj kev mob tshwm sim) - txog 21 hnub

2 x 500mg txog 2 x 750mg

2-4 lub lis piam (mob), 4-6 lub lis piam (mob)

Chaw mos kis tau tus mob

Kab mob ntsws thiab mob ncauj tsev menyuam

ib koob 500 mg

Orchoepididymitis thiab mob txha caj qaum ntawm cov plab hnyuv siab raum

2 x 500mg txog 2 x 750mg

tsis pub tsawg tshaj 14 hnub

Mob plab hnyuv thiab mob rau sab hauv plab

Zawv plab tshwm sim los ntawm kab mob kis, suav nrog Shigella spptshwj tsis yog Shigella dysenteriae hom I thiab kev kho mob rau cov neeg mob raws plab heev

Zawv plab los ntawm Shigella dysenteriae hom Kuv

Ciprolet tshuaj (ciprofloxacin) ntsiav tshuaj - dab tsi lawv pab los ntawm

Muaj ntau ntau yam kabmob uas "Tsiprolet" cov ntsiav tshuaj tau siv. Dab tsi lawv pab los ntawm:

• Cov mob ENT tshwm sim los ntawm kev kis mob,
• Mob ntsws, mob ntsws, mob ntsws,
• Cystitis, glomerulonephritis, pyelonephritis, mob ntawm cov hlab zis,
• Qhov chaw mos mob tshwm sim, cov kab mob hauv qhov,
• Cov mob txhab ntawm cov pob txha thiab pob qij txha,
• Lub plab zom mov
• O o thiab suppuration ntawm daim tawv nqaij.

Cov tshuaj muaj pes tsawg leeg

Cov Cheebtsam Me

Plhaub

Tsiprolet thiab Tsiprolet A: puas muaj qhov sib txawv

Ciprolet yog tshuaj tua kab mob uas yog los ntawm ib cov tshuaj, txij li thaum

Vim li cas Cyprolet A ntsiav tshuaj tau piav qhia hauv ntu no

ciprofloxacin ua raws li tus tshuaj tiv thaiv nkaus xwb ntawm cov tshuaj no.

Ciprolet A yog suav tias yog cov tshuaj sib xyaw ua keCov. Nws muaj 2 cov tshuaj nquag - ciprofloxation 500 mg thiab tinisadol 600 mg.

Qhov kev sib xyaw ua ke no ua rau nws muaj peev xwm kho tau ntau yam mob sib kis ntawm hom sib xyaw, thaum cov kab mob me me tau txuas rau lawv. Cov npe ntawm cov lus pom zoo thiab cov cim qhia rau kev nkag mus rau Tsiprolet thiab Tsiprolet A yog qhov qub, tsuas yog qhov thib ob yog siv rau hauv kev kho mob ntawm ntau qhov hnyav thiab qib ntxiv ntawm cov txhab txhab.

Cyprolet ntsiav tshuaj 250, 500 mg: cov lus qhia rau kev siv

Cov ntsiav tshuaj yuav tsum tau noj ntawm qhov ncauj tag nrho lub plab, ntxuav nrog me me ntawm cov dej. Thaum noj rau ntawm lub plab khoob, cov khoom xyaw nquag yog nqus tau sai dua.

Lub sijhawm ntawm kev pub nkag yog txiav txim siab los ntawm ntau qhov ntsuas:

• kev txhim kho ntawm tus kabmob
• hom mob
• los ntawm lub hnub nyoog
• xeev tiv thaiv kab mob
• cov yam ntxwv ntawm lub raum thiab mob siab.

Cov tshuaj tua kab mob tsis nres tom qab tshem cov tsos mob uas cuam tshuam, nws raug nquahu kom noj cov ntsiav tshuaj rau 2-3 hnub ntxiv. Lub sijhawm kho yog txiav txim los ntawm tus kws khomob tuaj koom.

Yuav haus li cas Tsiprolet: ntau npaum

Cov tshuaj pom zoo rau cov neeg laus:

Cyprolet hauv kev kho hniav

Ciprolet yog siv dav hauv kev kho hniav nrog rau lwm cov tshuaj tua kab mob. Cov ntsiav tshuaj ntawm cov tshuaj tua kab mob no pabcuam tawm tsam ntau yam mob ntawm tus mob thiab kis tau tus mob.

Cov kws kho mob hais tias lawv tseem ua tau zoo ntawm kev tiv thaiv ntawm suppuration tom qab kev phais mob.

Tom qab rho hniav

Kev siv tshuaj tua kab mob yog qhov tsim nyog tom qab rho hniav, txawm li cas los xij, ntawm kev txiav txim siab ntawm tus kws kho hniav, nws tuaj yeem raug tshem tawm lossis siv tsis txhua yog tias kev tshem tawm tsis cuam tshuam. Ciprolet ntsiav tshuaj tau sau tseg rau siv nyob rau hauv chav kawm ntawm 5 hnub 2 zaug hauv ib hnub, ib ntsiav tshuaj, uas ua rau txo kev pheej hmoo ntawm o, suppuration thiab tus kab mob.

Rau mob hniav

Cov tshuaj Ciprolet thaum nws nkag rau hauv lub cev pib nkag siab rau hauv cov ntshav. Tshuaj tua kab mob sai sai tshem tawm qhov mob, daws qhov mob thiab rhuav tshem cov kab mob. Cov tshuaj siv sijhawm li 4-5 teev, tom qab ntawd nws raug tso tawm los ntawm lub raum, los ntawm qhov nws tau khwv tau nws cov koob meej thiab siv thoob plaws.

Tshuaj tua kab mob zoo rau flux hauv thawj theem, thaum lub ntsej muag tsis tau tshwm sim, tom qab ntawd Ciprolet yuav tsum tau siv tsuas yog tom qab qhib qhov tsim. Cov kev kho mob niaj zaus yog 5 hnub, 1 ntsiav tshuaj txhua 12 teev.

Cyprolet nrog mob ntsws

Hauv cov xwm txheej uas ua rau mob ntsws txhawm rau mob voos, yog vim li cas rau kev teem caij kho tshuaj tua kab mob. Thaum hnoos qeev pom nyob rau hauv hnoos qeev lossis nrog feem ntau rov ua dua tus mob ntsws, cov tshuaj tua kab mob kuj tseem raug kho. Qhov zoo dua ntawm no yog muab rau cov ntsiav tshuaj.

Ciprolet pab tau zoo thaum nyuam qhuav pib mob ntawm mob ntsws lossis thaum lwm yam tshuaj tsis zoo. Lub chav kawm ntawm kev kho mob thiab kev noj tshuaj yog txiav txim siab tom qab tshuaj xyuas thiab sab laj nrog kws kho mob. Feem ntau, Ciprolet cov thawj coj kav tsis pub ntev tshaj 10 hnub, ib ntsiav tshuaj 2 zaug ib hnub.

Nrog angina

Nyob rau hauv cov xwm txheej txaus ntshai ntawm purulent tonsillitis thiab ua xua rau lwm cov tshuaj tiv thaiv kab mob, Ciprolet ntsiav tshuaj yog cov tshuaj, uas ua rau lawv tsis tuaj yeem tiv thaiv kev kho mob ntawm tus kab mob no. Feem ntau, nyob rau hauv cov mob huam mob plawv ntawm angina, cov tshuaj tua kab mob ntawm cov tshuaj penicillin thiab macrolide series tsis muaj zog.

Hauv kev mob siab heev ntawm angina, Ciprolet yog siv nyob rau hauv daim ntawv ntawm qhov kev daws teeb meem.

Cov koob tshuaj pom zoo ntawm cov tshuaj hauv cov ntsiav tshuaj rau cov laus hauv kev kho mob tonsillitis yog ib nrab ntsiav tshuaj 2-3 zaug hauv ib hnub. Siv tshuaj yaj yeeb los ntawm 7 mus rau 10 hnub.

Rau cov foos hnyav, 1-1.5 ntsiav tshuaj tau sau tseg 2-3 zaug, kuj yog 7-10 hnub. Thaum cov tsos mob tsis tshua muaj siab ntseeg, cov tshuaj tseem yuav raug noj rau lwm 3 hnub. Txog rau purulent tonsillitis, cov tshuaj tau muab tshuaj rau hauv cov tib neeg cov tshuaj hauv lub lim tiam 3-4 lub lim piam, txhawm rau txhawm rau tiv thaiv cov teeb meem.

Cov tshuaj Ciprolet nrog cov hlab ntsws mob

Cyprolet nrog cov leeg ntshav yog siv thaum cov kab mob kis tau rau nws. Cov tshuaj muaj cov kev mob tshwm sim, los ntawm qhov uas nws yog siv rau hauv qhov xwm txheej qhov kev kho mob nrog lwm cov tshuaj tau ua tsis muaj txiaj ntsig.

Cov neeg laus raug pom zoo kom noj 1 lub tshuaj ntawm Ciprolet 2 zaug ib hnub rau 5-7 hnub, nyob ntawm seb tus mob hnyav npaum li cas.

Cyprolet nyob rau hauv kev kuaj mob poj niam rau cystitis rau cov poj niam

Cyprolet tuaj yeem coj nyob rau txhua ntu thiab theem twg ntawm cystitis. Qhov ntau npaum li cas tau sau tseg los ntawm tus kws kho mob raws li tus neeg mob cov ntaub ntawv - hnub nyoog, qhov hnyav, nrog rau qhov mob hnyav thiab muaj cov kab mob concomitant.

Cov koob tshuaj pom zoo rau kev kho mob cystitis rau cov poj niam yog 2 ntsiav tshuaj hauv ib hnub nrog rau kev so 12 teev. Txoj kev kawm ntev li 5 txog 14 hnub. Cov kws tshaj lij qhia cov poj niam lub raum ua haujlwm kom txo qis qhov ntau npaum ntawm 2 cov tshuaj.

Nrog mob prostatitis

Hauv daim ntawv qhia meej txog tus mob prostatitis, kev tswj hwm ntawm kev siv tshuaj Ciprolet yog tus kws kho mob rov qab kho txoj kev, tom qab nws dhau mus rau theem ntawm kev tshem tawm, ntsiav tshuaj yog tshuaj. Hloov mus rau kev tswj hwm qhov ncauj tau ua haujlwm tau rau hnub 4 ntawm kev txhaj tshuaj.

Cov koob tshuaj pom zoo rau cov txiv neej nrog prostatitis yog 500 mg txhua 12 teev. Kev tos txais ntev 10 hnub, tuaj yeem txuas ntxiv nyob ntawm kev txiav txim siab ntawm tus kws kho mob. Nws kuj tsim nyog sau cia tias nyob rau ntawm qhov muaj lub raum lossis lub siab tsis ua haujlwm, ntau npaum ntawm Ciprolet yuav tsum tau txo qis 2 zaug.

Cyprolet rau menyuam: cov lus qhia rau kev siv

Cov tshuaj tua kab mob tsis raug tso cai rau cov menyuam yaus nyob rau lub sijhawm loj hlob mus txog 18 xyoo.

Yog tias cov duab hauv chaw kuaj mob yog qhov nyuaj, tom qab ntawv noj Ciprolet raug tso cai nyob rau hauv kev saib xyuas mob nkeeg los ntawm hnub nyoog 15, thaum muab tshuaj yuav tsum tau xam thiab kho ib tus zuj zus.

Cov koob tshuaj pom zoo kom tshem tawm cov kev mob tshwm sim los ntawm Pseudomonas aeruginosa hauv cov menyuam yaus uas muaj muscid pulmonary fibrosis nyob rau thaum hnub nyoog 5-17 xyoo yog 20 mg rau 1 kg ntawm lub cev qhov hnyav txhua 12 teev (qhov siab tshaj txhua hnub rau tus menyuam yuav tsum tsis pub tshaj 1500 mg). Txoj kev kawm ua haujlwm ntev 10-14 hnub.

Txog kev kho thiab tiv thaiv anthrax hauv daim ntawv ntsws, koj yuav tsum noj 15 mg rau 1 kg ntawm lub cev qhov hnyav txhua 12 teevCov. Qhov koob tshuaj ntau rau ib tus menyuam yuav tsum tsis pub ntau tshaj 500 mg, thiab qhov koob tshuaj txhua hnub yuav tsum tsis pub ntau tshaj 1000 mg. Lub sijhawm ua haujlwm kav 60 hnub.

Sab sij huam

Cov kev mob tshwm sim thaum noj cov tshuaj tuaj yeem pom los ntawm ob sab:

Tsis tas li ntawd, qhov tshwm sim ntawm kev ua kom tsis muaj zog thiab superinfection muaj peev xwm ua tau - candidiasis thiab pseudomembranous colitis.

Kuv tuaj yeem coj Cyprolet thaum cev xeeb tub?

Cov tshuaj tua kab mob Ciprolet hais txog cov tshuaj feem ntau uas txwv tsis pub siv thaum cev xeeb tub thiab thaum pub niam mis. Ciprolet tsis tau raug kuaj rau cov poj niam cev xeeb tub, yog li nws cov nyhuv ntawm tus menyuam hauv plab tsis tau kawm. Kev ntsuam xyuas tau ua los ntawm cov tsiaj.

Cyprolet thiab cawv - sib xyaw: yog tau haus

Thaum sib cuam tshuam nrog haus dej cawv, kev sib txuas ntawm daim siab enzymes uas ua cov tshuaj ethanol thiab nws cov khoom lwj tsis ua haujlwm.

Tom qab ntawd cov tsos mob ntawm intoxication intensify thiab lawv lub sijhawm, raug lom hnyav tshwm sim. Lawv cov qib raug cuam tshuam los ntawm cov neeg haus cawv thiab cov cawv hauv lub cev.

Kev cuam tshuam nrog lwm yam tshuaj

• thaum siv nrog cov tshuaj uas cuam tshuam rau qib acid ntawm lub plab kua txiv (antacids), cov khoom lag luam muaj aluminium hydroxide, magnesium, ntsev ntsev, hlau thiab zinc tuaj yeem pab txo qis kev nqus ntawm ciprofloxacin los ntawm lub cev, yog li koj yuav tsum tswj kev so kom ntev li 1 mus rau 4 teev nruab nrab ntawm lawv ,

• thaum noj cov theophylline, koj yuav tsum saib xyuas nws qhov kev xav, txij li nws tuaj yeem sawv siab hauv cov ntshav ntshav,
• thaum noj nrog cyclosporine, nyob rau qee kis, kev cia siab ntawm cov ntshav creatinine nce,
• thaum noj nrog warfarin, cov nyhuv ntawm ciprofloxacin tau txhim kho nyob rau qee kis,
• nyob rau ntawm lub koob tshuaj ntawm quinols thiab lwm yam tshuaj los tiv thaiv tsis ntaus tshuaj, txwv tsis pub muaj qhov cim tseg,
• cov tshuaj tuaj yeem ua ke thaum lub sijhawm kho nrog azlocillin, ceftazidime, meslocillin, azlocillin, azoxazoylpenicillins, vancomycin, metronidazole, clindamycin.

Tsuas tshuaj thiab tswj hwm

Cov ntsiav tshuaj yuav tsum tau noj ntawm qhov ncauj (sab hauv), tsis hais zaub mov, nrog kua me me. Cov ntsiav tshuaj yuav tsum nqos tag nrho yam tsis ntxo. Thaum noj Ciprolet rau ntawm lub plab khoob, nws yuav nqus sai dua, thiab koj yuav tsum tsis txhob haus cov tshuaj nrog cov khoom noj siv mis lossis haus uas muaj cov calcium. Cov calcium uas nyob hauv cov zaub mov tsis cuam tshuam rau kev nqus ntawm cov tshuaj.

• cov kab mob ua pa: 500-700 mg 2 zaug ib hnub,
• kev kis mob ntawm cov genitourinary system: mob hnyav, tsis mob - 250-500 mg 2 zaug hauv ib hnub, cystitis rau cov poj niam (ua ntej lub cev ntas) - 500 mg 1 lub sijhawm, muaj teeb meem - 500-750 mg 2 zaug hauv ib hnub, muaj mob ntawm chaw mos (tshwj tsis yog kab mob gonorrhea) - 500 –750 mg 2 zaug hauv ib hnub, kab mob gonorrhea - 500 mg 1 zaug hauv ib hnub, raws plab - 500 mg 2 zaug ib hnub,
• lwm yam mob: 500 mg 2 zaug ib hnub,
• Cov mob hnyav rau lub neej muaj sia (nrog rau mob ntsws, mob ntsws, mob pob txha thiab pob qij txha, mob txhaws ntswg, mob peritonitis): 750 mg 2 zaug ib hnub.

Pom zoo kom noj tshuaj rau cov neeg mob tshwj xeeb:

• cov neeg mob hnub nyoog tshaj 65 xyoos: koob tshuaj yuav tsum tau txo nyob ntawm qhov mob hnyav ntawm tus kabmob thiab creatinine ntshiab,
• lub raum tsis ua haujlwm: nrog creatinine tshem tawm los ntawm 30 txog 60 ml / min, qhov siab tshaj plaws ntawm ciprofloxacin yog 1000 mg / hnub, nrog creatinine tshem tawm hauv qab 30 ml / min - 500 mg / hnub, yog tias tus neeg mob nyob ntawm hemodialysis, Ciprolet yuav tsum tau noj tom qab nws. Rau kev kho mob sab nrauv qhov kev tawm tsam peritoneal lim ntshav tas mus li, qhov siab tshaj plaws niaj hnub noj tshuaj yog 500 mg.
• daim siab ua hauj lwm: koob tshuaj yuav tsis tas kho.

Lub sijhawm kho yog nyob ntawm tus mob hnyav, kab mob thiab kev tswj xyuas tus mob. Tom qab cov tsos mob ploj, kev tswj hwm kev siv tshuaj zoo yuav tsum tau txuas ntxiv mus yam tsawg 3 hnub ntxiv. Qhov nruab nrab ntawm kev kho mob ntev:

• mob tsis haum luag mob gonorrhea, cystitis: 1 hnub,
• kis kab mob ntawm lub raum, tso zis tawm, mob plab mob: txog 7 hnub,
• neutropenia hauv cov neeg mob immunocompromised: nws tag nrho lub sijhawm,
• osteomyelitis: tsis pub ntau tshaj 2 hlis,
• lwm yam mob: 7-14 hnub,
• mob tau los ntawm tus kab mob Streptococcusspp. thiab Chlamydiaspp.: tsawg kawg 10 hnub.

Txog kev tiv thaiv thiab kho mob ntsig txog mob ntsws anthrax: 500 mg 2 zaug ib hnub rau 60 hnub. Nws yuav tsum pib noj cov tshuaj tam sim ntawd tom qab kis tau tus kab mob (xav tias yog lossis paub tseeb).

Menyuam yaus thiab tub ntxhais hluas

Xav pom zoo muab tshuaj rau hauv qab no (tshwj tsis yog muaj lwm yam kev qhia):

• kev kho mob ntawm kev mob tshwm sim los ntawm Pseudomonas aeruginosa hauv cov menyuam yaus hnub nyoog 5-17 xyoo nrog mob ntsws ntsig: 20 mg / kg lub cev hnyav 2 zaug hauv ib hnub (ntau kawg noj ib hnub - 1500 mg). Lub sijhawm tiv thaiv tshuaj yog 10-14 hnub,
• kev tiv thaiv thiab kho mob ntsig txog mob ntsws (Bacillus anthracis): 15 mg / kg lub cev hnyav 2 zaug hauv ib hnub. Qhov nyiaj pab ntau tshaj txhua hnub yog 1000 mg. Lub sijhawm tiv thaiv ntawm cov tshuaj yog 60 hnub.

Txuas ntxiv rau kev daws teeb meem

Cov tshuaj tiv thaiv hauv zos muaj peev xwm ua tau: nrog lub sijhawm ntawm infusion tsawg dua 30 feeb, edema yog ntau dua (mob ntawm daim tawv nqaij ua xua). Qhov tshuaj tiv thaiv no tshwm sim nws tus kheej tom qab qhov kawg ntawm Txoj kev lis ntshav thiab tsis yog qhov tsis sib haum rau kev siv tshuaj ntxiv (yog tias nws qhov kev kawm tsis nyuaj).

Nws yog ib qho tsim nyog yuav tsum xav txog cov ntsiab lus ntawm sodium chloride nyob rau hauv kev daws rau cov neeg mob uas tsis muaj ntsev ntau.

Txuas ntxiv rau ntsiav tshuaj

Kev sib koom tes nrog cov kev npaj cationic, cov tshuaj muaj ntxhia muaj hlau, calcium, magnesium, hauv lub siab, tshuaj tiv thaiv kab mob, tshuaj tua kab mob, polymer phosphate tebchaw, aluminium, nrog rau kev npaj nrog lub peev xwm loj uas muaj cov khoom siv magnesium, calcium, aluminium, txo qhov nqus ntawm ciprofloxacin. Hauv qhov no, nws raug nquahu kom noj nws li 1-2 teev ua ntej lossis 4 teev tom qab noj cov tshuaj no. Qhov kev txwv no tsis siv rau chav kawm ntawm H2-histamine receptor blockers.

Cov khoom noj siv mis thiab dej haus uas muaj nplua nuj ntxiv yuav tsum tsis txhob noj ib txhij nrog Ciprolet, vim tias lawv tuaj yeem txo qhov nqus ntawm ciprofloxacin.

Tsifran lossis Tsiprolet: uas yog qhov zoo dua

Tsifran yog ib qho piv txwv ntawm Tsiprolet. Nws tseem ua haujlwm tawm tsam gram zoo thiab gram tsis zoo rau cov kab mob; fungi, virus, pathogens ntawm mob syphilis thiab qee yam muaj sia muaj zog tiv taus nws.

Ob qho tshuaj yeeb tshuaj muaj cov cim qhia zoo sib xws thiab sib kis.Tsis zoo li Cifran, Ciprolet cuam tshuam ntau dua nrog lwm cov tshuaj.

Tsipromed lossis Tsiprolet: uas yog qhov zoo dua

Tsipromed yog lwm qhov sib piv ntawm Tsiprolet, hauv nws cov muaj pes tsawg leeg ua tib yam nkaus. Cov 2 tshuaj no sib txawv ntawm tus nqi - yog tias Ciprolet tee yog 50-60 rubles hauv chaw muag tshuaj, ces Cipromed muaj txog 100-140 rubles. Cypromed muaj nyob rau hauv daim ntawv ntawm pob ntseg thiab qhov muag.

Cov tshuaj Ciprolet hauv cov ntsiav tshuaj zoo rau kev kho mob ntawm ntau yam kab mob thiab cov kab mob sib kis, los ntawm qhov nws nquag siv hauv tshuaj. Tus nqi qes thiab qhov muaj peev xwm siab, thaum xaiv cov tshuaj tua kab mob, tso cai rau koj ua tus xaiv hauv nws txoj kev nyiam.