Mob ntshav qab zib mellitus thiab nws cov kev kho mob
Rosinsulin yog ib qho tshuaj insulin uas tau siv ua qee yam ntshav qab zib. Nws yuav tsum tau qhia meej tam sim ntawd hais tias muaj ntau ntau yam ntawm cov tshuaj no:
- Rosinsulin P – Cov tshuaj insulin luv luv nrog qhov pib ntawm cov nyhuv, tom qab ib nrab teev los ntawm lub sijhawm ntawm kev tswj hwm thiab nws txoj kev loj hlob tshaj plaws nyob rau hauv 1-3 teev. Lub sijhawm tag nrho ntawm qhov kev txiav txim yog txog li 8 teev,
- Rosinsulin M sib tov – Qhov “Nruab Nrab” Insulinmuaj ob ntu (ib qho tshuaj lom neeg muaj tshuaj thiab cov khoom lag luam ntawm kev tsim kho tshuab, sib npaug rau tib neeg cov tshuaj hormones). Thawj cov cim ntawm kev ua ntawm cov tshuaj no tshwm sim li ib nrab teev tom qab kev tswj hwm, qhov siab tshaj plaws tshwm sim los ntawm plaub mus rau kaum ob teev, thiab tag nrho lub sijhawm ntawm cov nyhuv yog txog ib hnub,
- Rosinsulin C – Qhov “Nruab Nrab” Insulinmuaj tag nrho ntawm cov tshuaj insulin-isophan tau los ntawm kev tsim hluav taws xob. Tsis zoo li Rosinsulin M sib xyaw, cov nyhuv ntawm cov tshuaj no txhim kho nyob rau hauv ib teev thiab ib nrab, thiab nce mus txog qhov siab thiab kav ntev - ntev npaum li cov kev kho mob dhau los,
Cov tshuaj zoo sib xws xav tau rau cov neeg uas muaj cov tshuaj insulin tsis txaus. Qhov no ua rau muaj kev nce ntxiv hauv kev mloog zoo ntawm cov piam thaj hauv cov ntshav, ib qho kev ua txhaum ntawm nws txoj kev nqus los ntawm cov ntaub so ntswg, uas yog qhov txaus ntshai heev thiab tuaj yeem ua kom tsis muaj mob ntawm lub cev. Cov neeg mob ntshav qab zib, tau nkag siab txog cov txheej txheem nyuaj ntawm cov metabolism hauv qabzib, kawm paub ntsuas lawv tus mob kom zoo (ntsuas ntsuas nrog lub ntsej muag) thiab siv cov "ntev", "nruab nrab" lossis "luv" los kho nws.
Cov tshuaj no yog siv rau:
- Ntshav qab zib mob ntshav insulin-yam mob (yam I),
- Cov ntshav qab zib tsis yog-insulin-hom mob ntshav qab zib hom (hom II), thaum lub cev tsis raug tshuaj txaus rau cov tshuaj hypoglycemic,
- Tus kab mob ntshav qab zib ketoacidosis thiab coma,
- Mob ntshav qab zib los ntawm kev muaj menyuam hauv plab,
- Tswj qab zib nyob rau hauv cov neeg mob uas yuav tsum tau muaj kev phais mob, raug mob, raug kev txom nyem nyob rau theem mob kis tus kab mob kis tau yooj yim - nyob rau kis uas siv lwm yam kab mob ntshav qab zib tsis yooj yim sua,
Rosinsulin tso cov ntawv - kev daws thiab ncua kev txhaj tshuaj. Cov tshuaj no yog muab tshuaj subcutaneously (hauv qee qhov xwm txheej, mob leeg lossis intramuscularly). Tus nqi ntawm kev txau ntawm cov tshuaj no kuj nyob ntawm qhov chaw txhaj tshuaj - cov neeg mob paub txog qhov twg nws zoo dua rau kev txhaj tshuaj insulin hauv ntau yam xwm txheej. Nws yog ib qho tseem ceeb uas hloov qhov chaw txhaj tshuaj tas li kom tsis txhob muaj kab mob rau ntawm cov nqaij mos (lipodystrophy, thiab lwm yam).
Lub sijhawm ntawm cov thawj coj ntawm cov tshuaj sib txawv yog sib txawv thiab txuas nrog kev noj zaub mov. Piv txwv li, "luv" Rosinsulin P muab tshuaj rau kaum tsib mus rau nees nkaum feeb ua ntej noj mov. Thiab "qhov nruab nrab" Rosinsulin C, uas siv ib hnub ib zaug, feem ntau yog noj ib nrab ib teev ua ntej noj tshais. Txhua tus neeg mob tau txhim kho nws cov phiaj xwm rau kev siv ntau yam insulins, raws li cov ntaub ntawv glucometer ntawm kev saib xyuas cov kua nplaum hauv cov ntshav, cov yam ntxwv ntawm nws tus kab mob thiab kev ua neej.
Cov tshuaj yog contraindicated nyob rau hauv:
- Intolerance rau ib qho twg
- Kev Ntshav Qab Zib,
Cov poj niam cev xeeb tub thiab lactating tuaj yeem thiab yog tsim nyog, siv cov tshuaj insulin. Nws muaj kev nyab xeeb rau tus menyuam hauv plab thiab tus menyuam tshiab. Tab sis tus neeg mob yuav tsum tau soj ntsuam cov qib qab zib tas li, vim cov metabolism hauv cov piam thaj nws txawv heev thaum cev xeeb tub thiab tom qab yug menyuam.
Phiv thiab haus tshaj
Kev tsis haum siab rau qee hom tshuaj insulin tuaj yeem ua rau ua kev tsis haum tshuaj - los ntawm urticaria, ua npaws, ua tsis taus pa, txog kev npau taws.
Tsis tas li, kev loj hlob ntawm cov ntshav qab zib yog qhov ua tau, thawj cov cim ntawm uas yog pallor, tshee, ntxhov siab, palpitations, thiab lwm yam (nyeem ntxiv hauv tsab xov xwm tshwj xeeb txog tus mob no). Txhawm rau ua kom tus mob no hnyav ntxiv, qhov nce ntawm cov tshuaj tiv thaiv kev tiv thaiv cov ntshav hauv cov ntshav tuaj yeem ua rau hnyav dua.
Thaum pib, kev kho mob tej zaum yuav muaj nrog edema thiab qhov muag tsis pom. Ntawm qhov chaw txhaj tshuaj, liab liab, o, khaus, thiab kev puas tsuaj ntawm cov ntaub so ntswg adipose yog ua tau (nrog kev hno nquag nyob hauv tib thaj chaw).
Kev siv tshuaj ntau dhau ntawm Rosinsulin ua rau cov ntshav qab zib tsawg thiab yuav tsum muaj kev ntsuas xwm txheej ceev - los ntawm kev noj cov piam thaj nws tus kheej rau tus neeg mob, qhia txog cov piam thaj thiab glucagon daws teeb meem (nrog tsis nco qab).
Cov qauv ntsuas yog qhov pheej yig dua li Rosinsulin
Txij li thaum Rosinsulin tam sim no tsis muaj muag, thiab tau tshaj tawm rau cov tshuaj dawb xwb, hauv cov khw muag tshuaj koj yuav tsum xaiv nws cov tshuaj analogues thiab, dua li, lawv pheej yig dua. Piv txwv li, "insulin luv luv" yog:
Ntawm no, feem ntau kev lag luam Actrapid.
Kev ntsuas ntawm "nruab nrab" insulin Rosinsulin S thiab M sib tov yuav yog:
Ntawm no, Biosulin yog qhov pheej yig tshaj.
Kev txheeb xyuas txog Rosinsulin
Cov tshuaj no yog ntawm cov khoom lag luam hauv tsev - yog li ntawd, nws tau mob siab rau hauv kev kho mob ntshav qab zib. Nrog rau, nws yog cov tshuaj uas tam sim no, feem ntau nyob rau hauv daim ntawv tsis-txwv tsis pub hloov, tau muab tshuaj dawb rau hauv chaw kho mob. Yog lawm, qhov no ua rau muaj kev txhawj xeeb loj rau cov neeg mob thiab lawv cov kev txheeb xyuas ntawm Rosinsulin kom meej meej qhia qhov no:
- Kuv tus kws kho mob tau ntev ntev los qhia kuv txog Rosinsulin, qhuas nws. Tab sis kuv tiv. Txog tam sim no, muaj ib hnub lawv ncaj qha qhia kuv tias tam sim no tsuas yog siv cov tshuaj no. Thiab txhua tus neeg txawv teb chaws tuaj yeem yuav nrog lawv tus kheej siv. Lawv tseg kuv tsis muaj kev xaiv. Ua Vajtswv tsaug, Kuv tau dhau mus ib txwm. Tab sis tam sim no tsis muaj kev thaj yeeb nyab xeeb - Kuv niaj hnub tos kev tsim txom.
- Rau lub hlis dhau los ntawm Rosinsulin (txhais los ntawm kev siv dag zog yuam). Qab zib pib dhia. Thaum kho qhov koob tshuaj, tab sis qee zaum kuj cia li ntshai.
Qee tus neeg mob tau yoog cov tshuaj insulin no thiab tseem qhuas nws:
- Kuv pom tau hais tias feem ntau ntawm cov teeb meem yog los ntawm kev ntshai thiab kev tsis ntseeg. Yuav luag ib xyoos tam sim no kuv tau txhaj tshuaj Rosinsulin thiab kuv pom tias nws ua haujlwm zoo heev.
- Kuv tam sim pib txhaj tshuaj Rosinsulin hauv tsev kho mob. Qab zib tuav raws li nws yuav tsum tau. Yog li tsis txhob ntshai.
Qhov laj thawj tseem ceeb ua rau kev tsis txaus siab ntawm cov neeg mob ntshav qab zib yog tias rau lawv txoj kev siv ib lossis ntau dua insulin yog tus yuam sij rau ib txwm muaj. Tau ntau xyoo, cov neeg mob tau xaiv cov tshuaj, kho kev kho mob, kho lawv txoj kev ua neej ... Hauv qhov xwm txheej no, hloov (thiab feem ntau los ntawm kev txiav txim) rau lwm yam tshuaj yuav zoo li muaj kev puas tsuaj. Txawm hais tias qhov cuab yeej no yuav ua tau zoo heev.
Qhov laj thawj thib ob yog qhov tsis muaj kev ntseeg siab nyob hauv insulins nyeg. Cov tshuaj uas tau tsim nyob hauv peb lub teb chaws ua ntej yog qhov tsis zoo thiab tsis tuaj yeem sib tw, thiab tseem muaj ntau dua, hloov cov tshuaj yeeb tshuaj txawv teb.
Qhov tseeb, qhov zoo, nws yuav zoo rau txhua tus neeg mob kom tau txais "nws" cov tshuaj insulin - qhov kev kho mob uas zoo tshaj plaws rau nws. Tab sis, alas, hauv qhov xwm txheej tam sim no qhov no ua tsis tau. Txawm li cas los xij, kev cia siab thiab kev txiav txim siab ib txwm yuav tsum raug tswj hwm. Feem ntau ntawm cov neeg mob tau hloov lawv cov tshuaj ntau dua ib zaug - kev tswj tus kheej ntawm cov piam thaj thiab cov lus qhia kho mob raws sijhawm yog qhov tseem ceeb ntawm no. Thiab nws zoo li tias Rosinsulin yuav ua pov thawj nws cov hauj lwm zoo.
Re: Puas yog TseemYeej kom tes nrog Lee Teng Tua?
QVikin "Lub Yim Hli 28, 2010 9:57 teev tsaus ntuj
Re: Puas yog TseemYeej kom tes nrog Lee Teng Tua?
Chanterelle25 »Aug 29, 2010 10:44 AM
Re: Puas yog TseemYeej kom tes nrog Lee Teng Tua?
Irina "Lub Yim Hli 29, 2010 3:48 teev tsaus ntuj
Chanterelle 25 sau: Irina
Koj puas xav tias yooj yim nrhiav tus txiv nplua nuj hauv Ivanovo?
Los yog kev ua haujlwm muaj nyiaj txaus rau insulin thiab strips?
muaj tseeb tiag. nws yog twv yuav raug hu tsis yog hais txog Eve!
Txog txais insulin. Nws tau txais los ntawm kev sau npe. Kuv twb hais qhia koj txog qhov xwm txheej hauv Ivanovo. Kuv tsis paub ib qho mob ntshav qab zib ib zaug ntawm kuv lub hnub nyoog nrog peb uas yuav muab cov tshuaj insulin hauv vials. Feem ntau, tsuas yog hauv cov tsev kho mob ua qhov no rau cov pog xwb.
thiab yog, Kuv nco qab qhov tam sim no kuv tau rov qab rau koj nyob rau hauv LS cov lus nug. Kuv tabtom xav, tej zaum tom qab ntawd kuv yuav sau npe hauv Yves - Kuv yuav tsis muaj teeb meem dab tsi ntawm kev sau npe ntawm no.
Re: Puas yog TseemYeej kom tes nrog Lee Teng Tua?
Irina "Lub Yim Hli 29, 2010 3:53 teev tsaus ntuj
QVikin sau tau tias: Irina
Koj insulin thaum lub sijhawm muab rau qhov twg koj tau txais?
Kuv tau txais lawv nyob hauv thaj av Sverdlovsk, vim tias kuv muaj daim ntawv pom zoo nyob rau ntawd ..
Puas yog cov khoom lag luam uas koj sau txog coj los ntawm Sverdlovsk Cheeb Tsam? Thiab tag nrho cov xyoo thaum lawv tseem kawm, lawv tau tsav tsheb? Koj yuav nyob qhov twg?
yog, txawm tias nws tsav nws tus kheej lossis leej txiv - kuv niam kuv txiv nyob ntawd. thiab kuv yuav nyob rau - tamsim no - ntawm no. nws yog vim li cas kuv tsis mus sau npe ntawm no - Kuv tau sau (saum toj), tab sis yog tias kuv tuaj yeem tau txais lawv ib txwm nyob ntawm no, ces nws txhais tau tias kuv yuav tsum tau sau npe ntawm no, tej zaum hmm, Kuv xav paub tias yuav cia li yuav muaj ntau yam teeb meem los yog ntau ntawm lawv?
Re: Puas yog TseemYeej kom tes nrog Lee Teng Tua?
Elechka "Lub Yim Hli 29, 2010 11:09 PM
Re: Puas yog TseemYeej kom tes nrog Lee Teng Tua?
Irina "Aug 30, 2010 2:04 teev tsaus ntuj
Ua tsaug, El !!
cov lus txhawb tau yog bye.
Re: Puas yog TseemYeej kom tes nrog Lee Teng Tua?
Ntxhi Rau Hli 28, 2011 9:12 p.m.
Re: Puas yog TseemYeej kom tes nrog Lee Teng Tua?
ECB Vladimir »Jun 29, 2011 1:52 teev tsaus ntuj
Re: Puas yog TseemYeej kom tes nrog Lee Teng Tua?
Ntxhi »Jun 29, 2011 7:31 tsaus ntuj
Re: Puas yog TseemYeej kom tes nrog Lee Teng Tua?
ECB Vladimir Lub Rau Hli 30, 2011 03:06 AM
Re: Puas yog TseemYeej kom tes nrog Lee Teng Tua?
Ntxhi Lub Rau Hli 30, 2011 07:44
Re: Puas yog TseemYeej kom tes nrog Lee Teng Tua?
ECB Vladimir Rau Hli 30, 2011 10:36
Rosinsulin: tshuaj xyuas ntawm kev siv cov tshuaj insulin, cov lus qhia
Rosinsulin C yog muab tshuaj subcutaneously 1-2 zaug hauv ib hnub, txog ib nrab ib teev ua ntej noj mov. Txhua zaus, qhov chaw txhaj tshuaj yuav tsum tau hloov.
Hauv qee kis, tus kws endocrinologist tuaj yeem sau ntawv rau tus neeg mob txhaj tshuaj ntawm cov tshuaj.
- mob ntshav qab zib mellitus yam 1 thiab 2,
- nyob rau theem ntawm kev ua haujlwm rau hypoglycemic tshuaj hauv qhov ncauj,
- nrog kev kho ua ke (ib nrab tsis kam rau hypoglycemic qhov ncauj tshuaj),
- nrog mono - lossis kev sib txuas ua ke thaum lub sijhawm phais mob,
- nrog cov kab mob sib,
- nrog mob ntshav qab zib hauv cov poj niam cev xeeb tub, thaum kev noj zaub mov noj tsis tau ua rau cov nyhuv xav tau.
Tsuas tshuaj thiab tswj hwm
Raug tshem tawm rau kev txhaj tshuaj subcutaneous. Cov tshuaj tiv thaiv yog hypoglycemia, kev tiv thaiv tsis txaus.
Rosinsulin C yog muab tshuaj subcutaneously 1-2 zaug hauv ib hnub, txog ib nrab ib teev ua ntej noj mov. Txhua zaus, qhov chaw txhaj tshuaj yuav tsum tau hloov. Hauv qee kis, tus kws endocrinologist tuaj yeem sau ntawv rau tus neeg mob txhaj tshuaj ntawm cov tshuaj.
Ua tib zoo mloog! Kev tswjhwm ntawm insulin ntawm ib nrab sijhawm yog txwv tsis pub! Hauv txhua kis, tus kws kho mob ib leeg xaiv cov koob tshuaj, uas yuav yog nyob ntawm cov yam ntxwv ntawm chav kawm ntawm tus kab mob thiab cov ntsiab lus ntawm cov piam thaj hauv cov ntshav thiab zis.
Cov koob tshuaj li niaj zaus yog 8-24 IU, uas muab 1 zaug nyob rau ib hnub, rau qhov no koj tuaj yeem siv insulin koob txhaj nrog ib rab koob tshem tau.
Hauv cov menyuam yaus thiab cov neeg laus uas muaj qhov tsis txaus siab rau qhov tshuaj hormones, qhov koob tshuaj yuav raug txo mus rau 8 IU toj ib hnub, thiab, hloov pauv, rau cov neeg mob uas tsis tshua hnov qab - nce mus rau 24 IU ib hnub lossis ntau dua.
Yog tias qhov koob tshuaj txhua hnub ntau dua li 0.6 IU / kg, nws raug tswj hwm 2 zaug hauv ib hnub nyob rau ntau qhov chaw. Yog tias cov tshuaj tau muab tshuaj tso rau hauv ib qho ntawm 100 IU ib hnub lossis ntau dua, tus neeg mob yuav tsum tau pw hauv tsev kho mob. Qhov kev hloov ntawm ib qho tshuaj insulin mus rau lwm qhov yuav tsum tau ua nyob ntawm kev saib xyuas ntawm kws kho mob.
Cov Tshuaj Pharmacokinetics
Cov tshuaj yog hais txog cov tshuaj insulins nruab nrab, uas tau qhia:
- kom txo ntshav ntshav qab zib
- kom nce nqus ntawm cov piam thaj los ntawm cov ntaub so ntswg,
- lug txhim khu glycogenogenesis thiab lipogenesis,
- kom txo tus nqi ntawm cov piam thaj tso tawm los ntawm daim siab,
- rau cov synthesis protein.
Sab sij huam
- angioedema,
- txog siav
- urticaria
- txo hauv cov ntshav siab,
- npaws.
- tawm hws zoo,
- pallor ntawm daim tawv nqaij,
- kev tshaib kev nqhis
- lub plawv dhia
- ntxhov siab
- hws
- kev zoo siab
- tshee hnyo
- paresthesia nyob rau hauv lub qhov ncauj,
- tsaug zog
- nyuaj siab maum
- cwj pwm txawv
- txob taus
- tsis meej kev tsiv
- ntshai
- kev hais lus thiab pom kev qhov muag tsis zoo,
- insomnia
- mob taub hau.
Nrog kev ncua tsis tau txhaj, ib koob tshuaj qis, tawm tsam keeb kwm ntawm kev kis mob lossis kub taub hau, yog tias kev noj zaub mov tsis ua raws li, ntshav qab zib acidosis thiab hyperglycemia yuav pib:
- tsis qab los
- kev nqhis dej
- tsaug zog
- hyperemia ntawm lub ntsej muag,
- tsis nco qab txog thaum lub xeev tsis nco qab,
- transient tsis pom kev thaum pib ntawm txoj kev kho.
Cov lus pom zoo tshwj xeeb
Ua ntej koj sau cov tshuaj los ntawm cov vial, nco ntsoov tias txoj kev daws teeb meem kom pom tseeb. Yog tias muaj kev txo qis lossis cov hws khov hauv qhov kev npaj, tom qab ntawd nws siv tsis tau.
Qhov kub ntawm cov tshuaj rau kev tswj hwm yuav tsum sib haum rau chav tsev kub.
Tseem ceeb! Yog tias tus neeg mob tau mob kis, mob qog, hypopituitarism, Addison tus kab mob, mob raum tsis ua haujlwm, nrog rau cov neeg muaj hnub nyoog 65 xyoos, yuav tsum tau txhaj tshuaj kho cov tshuaj insulin.
Cov laj thawj ntawm kev ua ntshav siab tuaj yeem yog:
- Hloov chaw ntawm cov tshuaj.
- Noj ntau dhau.
- Tsis noj mov.
- Cov kab mob uas txo qis qhov xav tau ntawm cov tshuaj.
- Ntuav, raws plab.
- Kev ua haujlwm ntawm lub adrenal cortex.
- Kev ntxhov siab ntawm lub cev.
- Hloov thaj chaw txhaj tshuaj.
- Kev cuam tshuam nrog lwm yam tshuaj.
Thaum pauv tus neeg mob los ntawm tsiaj cov tshuaj insulin rau tib neeg cov tshuaj insulin, ua rau cov ntshav qab zib tsawg zuj zus.
Kev piav qhia ntawm kev nqis tes ntawm cov tshuaj Rosinsulin P
Rosinsulin P hais txog cov tshuaj uas muaj cov nyhuv luv luv hypoglycemic. Ua ke nrog cov receptor ntawm cov roj ntsha ntawm sab nraud, cov tshuaj ua rau cov insulin receptor complex. Qhov no ua:
- nce lub synthesis ntawm cyclic adenosine monophosphate nyob rau hauv daim siab thiab rog hlwb,
- txhawb cov txheej txheem intracellular (pyruvate kinases, hexokinases, glycogen synthases thiab lwm tus).
Txo hauv cov ntshav qab zib cov ntsiab lus tshwm sim vim yog:
- nce kev thauj intracellular,
- stimulation ntawm glycogenogenesis, lipogenesis,
- protein ua kom sib haum
- txhim kho kev nqus ntawm cov tshuaj los ntawm cov ntaub so ntswg,
- txo qis hauv kev puas tsuaj ntawm glycogen (vim txo qis ntawm cov piam thaj los ntawm nplooj siab).
Tom qab tswj hwm subcutaneous, cov nyhuv ntawm cov tshuaj tshwm sim hauv 20-30 feeb. Qhov siab tshaj plaws nyob rau hauv cov ntshav tau tiav tom qab 1-3 teev, thiab txuas ntxiv ntawm kev nqis tes ua yog nyob ntawm qhov chaw thiab txoj kev ntawm kev tswj hwm, koob tshuaj thiab tus yam ntxwv ntawm tus neeg mob.