Flowerpot: cov lus qhia rau kev siv, tshuaj xyuas thiab tus nqi

Vasonite muaj cov tshuaj pharmacological hauv qab no:

• txhim kho microcirculation ntshav rau hauv cov chaw ntawm cov ntshav ncig vim qhov kev txhim kho rheological ntshav cov ntshav (fluidity),
• tiv thaiv cov phab ntsa ntawm cov hlab ntsha los ntawm kev puas tsuaj (angioprotectivetxiav txim)
• relaxes cov leeg du ntawm cov phab ntsa ntawm cov hlab ntshav (cov nyhuv vasodilating),
• inhibits lub peev xwm ntawm cov ntshav mus mob ntsws vwm (anti-aggregation txiav txim)
• txhim kho cov pa oxygen rau cov ntaub so ntswg.

Tso tawm daim ntawv thiab muaj pes tsawg leeg

Cov tshuaj muaj nyob rau hauv daim ntawv ntawm lub caij nyoog-tso cov ntsiav tshuaj, zaj duab xis-coated, 600 mg (10 daim hauv ib lub hlwv, 2 lub hlwv hauv ib lub thawv ntawv).

Cov tshuaj muaj zog ntawm Wasonite yog pentoxifylline, raws li cov ntu pabcuam, cov tshuaj muaj:

• Microcrystalline cellulose - 13.5 mg,
• Colloidal silicon dioxide - 3 mg,
• Magnesium stearate - 4.5 mg,
• Hypromellose 15000 cp - 104 mg,
• Crospovidone - 15 mg.

Lub plhaub suav nrog:

• Talc - 11.842 mg
• Hypromellose 5 cP - 3.286 mg,
• Macrogol 6000 - 3.943 mg,
• Titanium dioxide - 3.943 mg,
• Polyacrylic acid (li 30% kev tawg) - 0.986 mg.

Cov Tshuaj Hauv Tshuaj

Pentoxifylline yog hais txog xanthine derivatives, uas ua rau kev txhim kho microcirculation hauv cov cheeb tsam uas tsis muaj ntshav txaus. Nws ua rau muaj kev txhim kho ntawm rheological tsis dhau ntawm cov ntshav (fluidity) vim muaj kev cuam tshuam rau kev deformability ntawm cov ntshav liab uas tau hloov pauv pathological. Pentoxifylline tseem normalizes lub elasticity ntawm erythrocyte membranes, inhibits platelet thiab erythrocyte kev sib xyaw thiab txo cov viscosity ntawm cov ntshav nce ntxiv.

Cov txheej txheem ntawm kev ua ntawm cov tshuaj nquag ntawm Wasonite yog qhia nyob rau hauv kev txwv tsis pub phosphodiesterase thiab kev sib txuam ntawm cyclic adenosine monophosphate (cAMP) hauv cov ntshav thiab cov hlwb ua rau cov leeg nqaij ntawm cov hlab ntsha. Pentoxifylline txo cov ntsiab lus ntawm fibrinogen hauv cov ntshav ntshav thiab ua kom cov ntshav fibrinolysis, uas ua rau txo qis ntshav viscosity thiab kev txhim kho ntawm nws qhov rheological, thiab tseem txhim kho cov ntaub so ntswg oxygen saturation nyob rau hauv thaj chaw uas cov hlab ntsha tsis tuaj yeem raug kuaj, tshwj xeeb hauv nruab nrab lub paj hlwb, nqua thiab ua kom tsawg dua ob lub raum. Nrog occlusive qhov txhab ntawm cov hlab ntsha peripheral, nrog kev sib cav sib ceg, Wazonite pab txo qhov mob thaum so, tshem tawm qhov tawv ncauj ntawm plab hlaub thaum hmo ntuj thiab nce kev deb ntawm taug kev. Nrog cerebrovascular cuam tshuam, pentoxifylline txhim kho cov tsos mob. Cov tshuaj pom muaj cov cim me ntsis myotropic vasodilating nyhuv thiab nthuav dav ntawm cov hlab ntshav hlab ntsha, nrog rau qhov txo qis me ntsis ntawm tag nrho cov kev tawm tsam mob vascular.

Cov Tshuaj Pharmacokinetics

Tom qab lub qhov ncauj tswj hwm, pentoxifylline yog yuav luag yaim los ntawm cov hnyuv. Nws yog tso tawm hauv lub cev ntev, uas ua kom muaj kev sib txuas ntxiv ntawm cov tshuaj thiab nws cov teeb meem tsis sib xws hauv lub cev. Pentoxifylline yog cov tshuaj tiv thaiv kab mob hauv lub siab, ua haujlwm kom dhau thawj qhov kev sib txuas nrog kev tsim ob lub tshuaj kws kho mob cov tshuaj: 1-5-hydroxyhexyl-3,7-dimethylxanthine (metabolite I) thiab 1-3-carboxypropyl-3,7-dimethylxanthine (metabolite V). Qib ntawm cov metabolites Kuv thiab V hauv cov ntshav ntshav, feem, yog 5 thiab 8 npaug ntau dua li uas ntawm pentoxifylline nws tus kheej. Thaum tswj hwm qhov ncauj ntawm Wazonite hauv cov qauv tshuaj, cov ntsiab lus siab tshaj plaws ntawm pentoxifylline thiab nws cov tshuaj tiv thaiv kab mob hauv cov ntshav ntshav tau pom nyob 3-4 teev tom qab kev tswj hwm, thiab cov txiaj ntsig kho tau ntev ntev li 12 teev. Kev nqhis dej ntawm cov tshuaj yog nqa tawm feem ntau los ntawm lub raum (li ntawm 94%) hauv daim ntawv ntawm metabolites. Nws kis mus rau niam cov kua mis thiab. Nrog rau daim siab ua rau lub siab ua haujlwm tsis zoo, qhov nthuav tawm ntawm metabolites ua rau qis qis. Nrog lub siab ua haujlwm tsis zoo, kev nce siab hauv kev ua haujlwm ntawm bioavailability thiab nce ntxiv hauv ib nrab lub neej.

Kev ntsuas rau siv

Raws li cov lus qhia, Vasonite yog siv rau hauv cov xwm txheej hauv qab no:

• Ntev thiab mob hnyav cerebrovascular ntawm ischemic keeb kwm,
• Dyscirculatory thiab atherosclerotic encephalopathy, angioneuropathy (Tus Kab Mob Raynaud, paresthesia),
• Circulatory mob ntawm lub qhov muag (mob ntev thiab mob circulatory tsis ua hauj lwm hauv choroid lossis retina ntawm lub qhov muag),
• Kev puas siab puas ncig ntawm peripheral ncig tiv thaiv keeb kwm ntawm cov ntshav qab zib, atherosclerotic thiab cov txheej txheem mob (suav nrog kev cuam tshuam tsis sib haum los ntawm obliterating endarteritis, atherosclerosis, thiab mob ntshav qab zib angiopathy),
• Cov mob ntawm cov nqaij mos uas tshwm sim rau keeb kwm yav dhau los ntawm cov leeg nqaij lossis cov hlab ntsha tsis huv ntawm cov leeg (trophic ulcers, frostbite, post-thrombophlebitis syndrome, gangrene),
• Kev txiav txim siab ntawm nruab nrab pob ntseg ntawm keeb kwm vascular, nrog cov lus tsis hnov ​​zoo.

Tsis tas li, Vasonitis yog raug kho rau qhov kev mob tshwm sim ntawm kev rau txim ntawm cerebrovascular kev huam yuaj ntawm atherosclerotic keeb kwm (kiv taub hau, tsis hnov ​​qab thiab tsis nco qab).

Cov Yuav Tsum Muaj

Cov Lus Cog Tseg txog kev siv Wazonite yog:

• Loj heev los ntshav
• Mob ntshav siab hauv lub hlwb
• Mob myocardial infarction,
• Mob ntshav dhia,
• Hypersensitivity rau lub Cheebtsam ntawm cov tshuaj thiab lwm cov methylxanthine derivatives,
• Cev xeeb tub thiab lactation
• Hnub nyoog qis dua 18 xyoo (kev nyab xeeb thiab kev ua haujlwm ntawm cov tshuaj rau cov pab pawg hnub nyoog no tseem tsis tau tsim).

Nrog kev ceev faj, Vasonite yog tshuaj rau:

• Cov leeg ntshav siab,
• Mob plawv nres
• Lub plawv tuaj kev ntxhov siab
• Atherosclerosis ntawm hlab ntshav / thiab hlab hlwb,
• Raum thiab mob siab mob raum,
• Nce los ntshav ntau
• Peptic rwj ntawm lub plab thiab duodenum,
• Cov xwm txheej tom qab kev phais tsis ntev los no (vim yog qhov txaus ntshai los ntshav).

Cov lus qhia rau kev siv vasonite: txoj kev thiab qhov ntau npaum li cas

Cov tshuaj yuav tsum tau noj nyob rau hauv lub qhov ncauj tom qab noj mov, tsis tas ua txhaum lub sam xeeb ntawm kev ncau thiab haus dej haus dej kom ntau.

Feem ntau, nws raug nquahu kom noj 1 lub tshuaj ntawm 600 mg ntawm Wazonite thaum sawv ntxov thiab yav tsaus ntuj. Qhov siab tshaj plaws niaj hnub noj tshuaj yog 1200 mg.

Lub sijhawm ua haujlwm ntawm kev kho thiab qhov ntau npaum li cas yog txiav txim los ntawm tus kws kho mob raws li kev soj ntsuam daim duab ntawm tus kab mob thiab ua tiav cov txiaj ntsig kho tau.

Hauv kev kho mob ntawm cov neeg mob kev txom nyem los ntawm kev mob raum tsis zoo (CC tsawg dua 30 ml / min), ib koob tshuaj ntawm Wasonit 600 mg yuav tsum tsis txhob siv.

Hauv cov neeg mob uas muaj mob nyhav rau daim siab hnyav, yuav tsum tau txo qhov hno kom noj tshuaj kom zoo rau ib leeg.

Kev kho mob ntawm cov neeg mob ntshav qis, nrog rau cov neeg mob uas muaj kev pheej hmoo vim tias qhov txo qis yuav ua rau muaj ntshav siab (hemodynamically tseem ceeb stenosis ntawm cov hlab ntsha hlwb, ib daim ntawv hnyav ntawm cov mob plawv), nws raug nquahu kom pib nrog kev noj me me. Hauv cov xwm txheej zoo li no, tsuas yog nce me ntsis hauv koob tshuaj tso cai.

Sab sij huam

Kev siv vasonite tuaj yeem ua rau cov kev mob tshwm sim hauv qab no:

• Los ntawm lub plab zom mov: mob raws plab, xeev siab thiab ntuav, mob epigastric, qhov ncauj qhuav, tsis qab los noj mov, kev hnov ​​qab ntawm lub cev thiab lub siab nyob rau hauv lub plab, plab hnyuv atony, mob cholestatic mob siab, exacerbation ntawm cholecystitis, nce kev ua si ntawm alkaline phosphatase thiab daim siab enzymes,
• Los ntawm lub hauv nruab nrab hauv lub paj hlwb: mob taub hau thiab kiv taub hau, pw tsaug zog ntxhov siab, ntxhov siab, mob plab, raug mob ntawm kev txhim kho cov mob aseptic meningitis,
• Los ntawm cov hlab plawv: tachycardia, arrhythmia, txo cov ntshav siab, muaj mob ntawm angina pectoris, cardialgia,
• Los ntawm cov kab mob hemopoietic thiab homeostasis: tsis tshua muaj - thrombocytopenia, pancytopenia, ntshav qog ntshav tsis txaus, mob qog ntshav, mob ntshav tsis txaus, ntshav tawm (los ntawm txoj hnyuv, hlab plab, cov leeg thiab cov tawv nqaij). Hauv cov txheej txheem ntawm kev kho, kev saib xyuas txhua zaus ntawm daim duab paj ntshav peripheral yog tsim nyog,
• Ntawm ib feem ntawm daim tawv nqaij thiab cov rog rog subcutaneous: yaug ntawm lub ntsej muag thiab lub hauv siab, nce ntawm qhov tsis zoo ntawm cov ntsia hlau, plhu ntawm lub ntsej muag, o,
• Ntawm feem ntawm cov plab hnyuv siab raum ntawm lub zeem muag: pom qhov tsis zoo, scotoma,
• Kev tsis haum cov tshuaj tiv thaiv: hyperemia ntawm daim tawv nqaij, Quincke's angioedema, pruritus, urticaria, anaphylactic shock.

Noj ntau dhau

Nrog kev noj tshuaj ntau dhau ntawm Vasonitis, qhov tshwm sim ntawm cov tsos mob xws li tsis muaj zog, tsaug zog, kiv taub hau, hyperemia ntawm daim tawv nqaij, qhov cim tseg ntawm cov ntshav siab, tachycardia, areflexia, ua npaws (ua daus no), thiab tsaus muag yog ua tau. Qee zaum kev siv tshuaj ntau dhau nrog nrog ntuav ntawm hom "kas fes thaj av", uas qhia txog txoj hnyuv txhaws ntshav, thiab tonic-clonic qaug dab peg.

Raws li kev kho mob, kev ua kom lub plab zom mov yog qhov pom zoo, tom qab los ntawm kev noj cov roj carbon activated. Yog tias ntuav tshwm sim nrog ntshav tawm, mob plab zom mov yog ua kom nruj. Yav tom ntej, kev kho cov tsos mob yog kws kho, tswj kev ua kom ntshav siab thiab lub ntsws ua haujlwm. Txog kev chua leeg, diazepam yog kev pom zoo.

Cov lus qhia tshwj xeeb

Thaum kho, nws yog qhov tsim nyog los tswj ntshav siab. Rau cov neeg mob uas tsis muaj ntshav khov thiab tsis ruaj khov, qhov tshuaj yuav tsum raug txo kom tsawg.

Thaum lub raum tsis zoo, kev kho mob raug pom zoo los ntawm kev saib xyuas zoo ntawm tus kws kho mob.

Yog tias muaj hemorrhage hauv retina ntawm lub qhov muag, kev siv Wazonite yuav tsum tsis ua mus ntxiv.

Kev tswj hwm ntawm hematocrit thiab hemoglobin yog qhov tsim nyog hauv kev kho mob ntawm cov neeg mob uas nyuam qhuav phais mob.

Nrog rau kev siv ua ke ntawm cov tshuaj tiv thaiv thiab vasonitis, ntsuas qhov ntsuas ntawm cov ntshav coagulation system (suav nrog INR) yuav tsum tau saib xyuas.

Hauv kev kho mob ntawm cov neeg mob ntshav qab zib mellitus noj tshuaj hypoglycemic, yuav tsum tau txhaj tshuaj kho, vim tias kev sib xyaw ua ke ntawm Wazonite hauv kev noj tshuaj ntau yuav ua rau kev txhim kho hypoglycemia.

Kev kho txoj kev kho mob rau cov neeg laus laus yuav tsum tau txo koob tshuaj, vim txo qis hauv qhov ua kom tshem tawm thiab ua kom lub cev muaj zog tuaj.

Hauv kev kho mob, nws raug nquahu kom tsis pub haus dej haus cawv.

Kev haus luam yeeb tuaj yeem pab txo cov nyhuv kho mob ntawm Wazonite.

Thaum tsav tsheb thiab kev pabcuam kev pabcuam nyuaj, yuav tsum saib xyuas, txij li thaum siv cov tshuaj yuav ua rau kiv taub hau.

Yeeb tshuaj sib cuam tshuam

Pentoxifylline muaj peev xwm txhim kho cov nyhuv ntawm cov tshuaj ua rau cov ntshav coagulation system (thrombolytics, tsis ncaj qha thiab ncaj qha anticoagulants), valproic acid, tshuaj tua kab mob (suav nrog cephalosporins - cefotetan, cefoperazone, cefamandol). Ntxiv cov txiaj ntsig ntawm hypoglycemic cov neeg sawv cev rau kev tswj hwm ntawm qhov ncauj, insulin thiab cov neeg sawv cev antihypertensive.

Cimetidine nce qib ntawm pentoxifylline hauv ntshav ntshav (tejzaum nws kev loj hlob tshwm sim). Kev siv ua ke ntawm vasonite nrog lwm cov xanthines tuaj yeem ua rau poob siab. Hauv qee tus neeg mob, kev sib xyaw ntawm theophylline thiab pentoxifylline tuaj yeem ua rau qhov nce ntawm theophylline concentration, uas yog nrog kev pheej hmoo ntawm kev mob tshwm sim cuam tshuam nrog theophylline.

Cov Lus Cim ntawm Wasonite yog: Pentilin, Pentilin Forte, Pentoxifylline-Acre, Trental 400.

Kev txheeb xyuas txog Wasonite

Kev tshuaj xyuas ntawm Wazonite ntawm cov neeg mob feem ntau zoo. Thaum siv cov tshuaj nyob rau hauv txoj kev kho mob ntawm ntau yam kab mob nrog los ntawm kev tiv thaiv peripheral ncig, ib tug maj mam txhim kho nyob rau hauv lub zwj ceeb ntawm cov neeg mob yog pom. Txawm li cas los xij, nws yuav tsum nco ntsoov tias txhua yam vascular nyuaj rau kev kho mob, uas yuav tsum tau kho txoj kev kho mob ntev ntev nyob rau hauv kev saib xyuas ntawm tus kws tshaj lij.

Tseem tseem muaj kev tshuaj xyuas tsis zoo txog cov tshuaj cuam tshuam nrog kev noj ntau dhau thiab phiv pentoxifylline. Yog li, kev noj haus Vasonitis yog kev pom zoo tsuas yog tom qab teem caij ntawm tus kws kho mob, uas yuav siv mus rau hauv txhua tus cim thiab contraindications.

Cov nyhuv Pharmacological

Vasonite txhim kho microcirculation thiab rheological zog ntawm cov ntshav, muaj cov nyhuv vasodilating. Nws muaj pentoxifylline, ib qho xanthine derivative, ua cov tshuaj nquag. Lub tshuab ntawm kev ua yog txuam nrog kev txwv tsis pub phosphodiesterase thiab kev txuam nrog cAMP hauv cov leeg nqaij mos ntawm cov hlab ntsha, hauv cov khoom tsim ua kom ntshav, hauv lwm cov nqaij thiab cov plab hnyuv siab raum.

Cov tshuaj inhibits kev sib sau ntawm platelets thiab cov ntshav liab, ua rau lawv cov elasticity, txo qib fibrinogen hauv cov ntshav plasma thiab ua kom cov fibrinolysis, uas txo cov viscosity ntawm cov ntshav thiab txhim kho nws cov rheological. Nws txhim kho cov ntaub so ntswg oxygen muab rau hauv thaj chaw ntawm qhov tsis muaj zog, tshwj xeeb tshaj yog nyob rau ntawm cov nqua, cov hlab ntsha hauv nruab nrab, thiab, kom tsis muaj qis dua, hauv lub raum. Tsawg me ntsis dilates cov hlab ntshav hlab ntsha.

Sab sij huam

Thiab kev tshuaj xyuas ntawm Wasonite, thiab cov kws kho mob sau tseg tias muaj kev phiv los ntawm ntau yam kev siv lub cev, xws li:

1. Los ntawm ib sab ntawm lub hauv nruab nrab hauv lub paj hlwb: mob taub hau thiab kiv taub hau, nrog rau kev pw tsaug zog, ntxhov siab vim, txawm hais tias muaj qhov tshwm sim tsawg tsawg,
2. Los ntawm lub plab zom mov: tsis qab los noj mov, raws plab, xeev siab thiab ntuav, mob epigastric, zoo nkaus li muaj puv plab zom mov,
3. Los ntawm hemopoietic thiab cov ntshav coagulation system: los ntshav hauv cov leeg nqaij, daim tawv nqaij, lub plab zom mov, ntxiv rau qhov mob ntshav tsis txaus, thrombocytopenia. Thaum noj Wasonite, yuav tsum saib xyuas cov ntshav tas mus li,
4. Los ntawm cov hlab plawv: tachycardia, ntsej muag ntxig dej, txo ntshav siab, angina pectoris, mob plawv atherosclerosis - cov tsos mob no tshwm sim nrog kev siv tshuaj ntau,
5. Kev tsis haum tshuaj: tawv nqaij ua pob khaus, khaus, urticaria, anaphylactic ceeb (tsis tshua muaj heev), Quincke's edema.

Cov tshuaj Vasonit - phiv

Vasonite muaj ntau qhov kev phiv los ntawm lwm qhov hauv nruab nrog cev thiab kab ke.

Los ntawm cov leeg hauv nruab nrab - Qhov no yog kiv taub hau heev, suav nrog tsaus muag, mob taub hau, tsaug zog, lossis insomnia, kev tuaj yeem nyeem ntawv, kev cais tawm ntawm kev nthuav dav mob hlwbCov. Kiv taub hau tuaj yeem tsim ib qho kev cuam tshuam rau kev tsav tsheb, yog li thaum kho tsis tsav tsheb.

Los ntawm circulatory system - lub plawv dhia ntau ntxiv, lub plawv dhia nrhoo, mob plawv (suav nrog hauv chua leeg) angina pectoris), txo qis ntshav siab (qee zaum ntse thiab tseem ceeb).

Txij li ntawv los xav - ua txhaum ntawm qhov pom tseeb tseeb, ploj ntawm qhov pom kev pom kev pom.

Los ntawm lub plab zom mov - Tsis qab los noj mov, qhov ncauj qhuav, xeev siab, ntuav, raws plab, hloov nrog cem quavmob hnyav thiab mob hauv plab.

Los ntawm daim siab thiab nplooj siab- mob nyob rau hauv txoj cai hypochondrium, hloov pauv lub siab ua haujlwm, exacerbation ntawm mob ua haujlwm ntawm cov kua tsib cov leeg thiab mob zais zis (mob ntev cholangitis thiab cholecystitis).

Los ntawm cov ntshav system - nce ntshav tawm los, los ntshav los ntawm cov plab hnyuv siab raum, cov pos hniav, txha ntswg, txo qis ntshav ntawm tag nrho cov xovtooj ntawm tes, feem ntau platelet suav thiab ntshav dawbCov. Kev loj hlob los kuj ua tau. anemia.

Ntawm ib feem ntawm daim tawv nqaij thiab nws txuas- Tso dej tawm ntshav mus rau sab saud ib nrab ntawm lub cev thiab lub ntsej muag, o, tawg yooj yim ntawm cov ntsia hlau.

Cov tshuaj yuav ua tau ua xua, uas manifests nws tus kheej hauv daim ntawv urticaria, Quincke edemadaim tawv nqaij ua pob thiab khaus. Tej zaum qhov kev loj hlob ntawm kev tsis haum tshuaj loj nyob rau hauv daim ntawv ntawm anaphylactic poob siab.

Vazonit - cov lus qhia rau kev siv

Lub lauj kaub Nws raug nquahu kom noj 600 ntsiav tshuaj ib hnub ob zaug tom qab noj mov, tsis tas yuav zom thiab haus nrog dej.
Rau cov neeg mob ib leeg, ntau npaum li cas ntawm cov tshuaj, tib lub sijhawm ntawm kev noj cov ntsiav tshuaj yog xaiv ib tus zuj zus los ntawm tus kws kho mob.

Yog li, cov lus qhia rau kev siv Wazonite rau kev kho mob ntawm cov neeg mob uas muaj lub siab thiab lub raum tsis ua haujlwm, ntshav siab thiab nyob rau hauv lub hnub nyoog laus pom zoo txo ​​cov tshuaj tsawg.

Kev sib cuam tshuam ntawm Wazonite nrog lwm yam tshuaj

Cov tshuaj cuam tshuam nrog ntau cov tshuaj muaj zog, nws ua rau kom muaj txiaj ntsig:

• tshuaj uas tsim kev txiav txim ntawm cov ntshav coagulation system - ncaj qha thiab tsis ncaj tshuaj thaiv tsev thiab lwm tus
• tshuaj tua kab los ntawm pab pawg cephalosporins(Xws li. ceftriaxone),
• valproic acid - cov tshuaj nrog cov nyhuv anticonvulsant,
• tshuaj kho ntshav siab,
• tshuaj kho mob ntshav qab zib.

Thaum noj nrog theophylline kev siv dhau ntawm qhov kawg yuav tshwm sim.

Thaum noj nrog cimetidine muaj kev pheej hmoo ntawm kev siv ntau tshaj ntawm Wasonite.

Analogs ntawm Wasonite

Analogs yog cov tshuaj ntawm cov pab pawg sib txawv uas tau siv los kho tib yam kab mob. Ib qho piv txwv ntawm Wasonite yog Xanthinol Nicotinate (Kev qhuas, Thiokol) - cov tshuaj uas muaj cov nyhuv zoo sib xws, tab sis cov tshuaj ua kom lub zog sib txawv. Nws txhim kho peripheral ntshav ncig (nrog rau cov ntshav ncig hauv lub hlwb thiab hloov khoom hauv lub zeem muag), nce qhov kev xa tawm thiab kwv yees pa oxygen los ntawm lub hlwb hlwb, txo qis platelet aggregation.

Tso tawm daim ntawv, muaj pes tsawg leeg tshuaj

Flowerpot tau ua tsuas yog hauv ib hom. Daim ntawv muab tshuaj - ua ntev ntsiav tshuaj. Txhua tus rub tawm yog npog nrog cov nyias zaj duab xis, muaj ib lub qe kheej tiv thaiv ntawm ob tog. Lub ntsiab ua haujlwm tseem ceeb yog pentoxifylline.

Txhua lub ntsiav tshuaj muaj 600 mg ntawm cov tshuaj. Muaj pes tsawg leeg ntawm lub plhaub suav nrog macrogol 6000, polyacrylic acid, titanium dioxide, talc. Cov ntsiav tshuaj tau ntim rau hauv lub hlwv ntawm 10 daim txhua. Paj Ntoo tau muab tso rau hauv cov thawv thawv ntawv nrog rau cov lus xaiv. Hauv ib pob muaj peev xwm muaj 1-2 lub hlwv.

Tus txheej txheem ntawm kev txiav txim, pharmacokinetics

Vasonite yog tsim los ua kom microcirculatory, rheological zog ntawm cov ntshav. Nws muaj cov vasodilating, cov tshuaj angioprotective. Pentoxifylline, ib qho ntawm cov xanthine derivatives, ua lub luag haujlwm tseem ceeb. Lub cuab yeej inhibits phosphodiesterase, txhawb kev tsub zuj zuj ntawm cyclic adenosine monophosphates.

Cov tshuaj thaiv txoj kev ua kom cov ntshav liab, platelets, nce ntxiv rau lawv txoj kev ywj pheej, txo qib fibrinogen. Pentoxifylline tseem muaj cov txiaj ntsig nthuav dav rau cov hlab ntsha hlab ntsha, rov qab thauj cov pa oxygen hauv cov cheeb tsam uas tsis muaj peev xwm ua haujlwm. Muaj txiaj ntsig zoo ntawm cov hlab ntsha hauv nruab nrab, cov hlab hlwb ncig mus rau ib qho me me ntawm lub raum.

Pentoxifylline tseem muaj qhov ua tau zoo ntawm kev yeej ntawm cov hlab ntsha peripheral, tshem tawm cov leeg mob yav hmo ntuj, thiab txo qhov hnyav ntawm qhov mob. Cov lus qhia rau cov tshuaj kuj piav qhia me ntsis myotropic, vasodilating nyhuv.

Kev kho kom haum tuaj yeem ntev txog 12 teev.

Nrog kev tswj hwm qhov ncauj ntawm Wazonite, cov tshuaj ua kom nquag plias yuav luag 100% nqus los ntawm lub plab zom mov. Tus neeg sawv cev muaj qhov cuam tshuam lub sijhawm ntev, thaum lub ntsiab lus raug tso tawm tsis tu ncua, thiab tom qab ntawd tusyees nqus tau. Qhov ntau kawg ntawm cov tshuaj nyob rau hauv cov ntshav tom qab kev tswj hwm yog tsau tom qab 3-4 teev. Cov tshuaj yuav raug tshem tawm yuav luag tag nrho los ntawm lub raum. Qhov kev cia siab nrog lub mis niam sau tseg.

Ntau yam ntawm kev pub nkag, txhaj tshuaj

Raws li cov lus piav qhia, Vasonite noj qhov ncauj tom qab noj mov, tsis muaj qhov tawg, ntxuav tawm nrog cov kua uas yuav tsum muaj. Cov qauv muab tshuaj yog 1 600 mg ntsiav tshuaj thaum sawv ntxov thiab yav tsaus ntuj. Qhov tshuaj ntau ntau rau ib hnub yog 1200 mg. Lub sijhawm rau kev kho kom zoo yog kho los ntawm tus kws kho mob nyob ntawm qhov mob hnyav, cov duab hauv chaw soj ntsuam ntawm tus kab mob.

Hauv kev kho mob hauv cov neeg mob uas muaj kev puas tsuaj rau daim siab thiab lub raum, kev txo qis hauv cov qauv tshuaj yog yuav tsum nyob ntawm kev kam ntawm cov tshuaj. Yog tias cov creatinine tshem tawm tsawg dua 30 ml / min, qhov ntau tshaj plaws tau tso cai rau khob yuav tsis pub tshaj 600 mg. Hauv kev kho mob ntawm cov neeg mob ntshav qis, txoj kev kho mob pib nrog kev txhaj tshuaj me me (150-300 mg), maj mam nce ntxiv, thaum ntsuas cov ntsuas.

Cov tshuaj zoo sib xws

Yog tias nws tsis tuaj yeem siv Wazonit, nws yog qhov tsim nyog yuav tshuaj rau lwm cov tshuaj uas zoo sib xws hauv kev nqis tes ua. Qee qhov analogues pheej yig dua li cov tshuaj tau piav, yog li cov neeg mob nyiam xaiv lawv.

Cov tshuaj muaj npe tuaj yeem nthuav tawm nyob rau hauv hom kev daws teebmeem kev txhaj tshuaj. Hauv kev kho mob hnyav, nws yog qhov zoo dua rau kev txhaj tshuaj, txij li kev txhaj tshuaj ntawm cov tshuaj tau lees paub tias ua haujlwm tau zoo dua.

Tsuas tshuaj thiab tswj hwm

Los ntawm cov lus qhia rau Wazonit, koj tuaj yeem pom tias cov tshuaj yuav tsum tau noj tom qab noj mov, tsis tas yuav zom thiab haus cov dej haus ntau. Feem ntau, tus kws kho mob txiav txim qhov ntau thiab ntau npaum li cas ntawm kev kho mob raws li keeb kwm, hom thiab theem ntawm tus kab mob. Tab sis, qhov pib, qhov nruab nrab qhov ntau yog 1 ntsiav tshuaj ib hnub ob zaug.

Qhov siab tshaj plaws rau kev noj tshuaj yog 1.2 g ib hnub.

Cov lus qhia rau kev siv Vazonit 600 mg, noj ntau npaum

Cov ntsiav tshuaj yuav tsum tau noj ntawm qhov ncauj, tsis tas yuav zom thiab haus dej kom ntau, zoo dua yog tom qab noj mov tas.

Cov qauv tshuaj rau, raws li cov lus qhia rau kev siv Vazonit - 1 ntsiav tshuaj ntawm Vazonit 600 mg 2 zaug hauv ib hnub. Qhov siab tshaj plaws niaj hnub noj tshuaj yog 1200 mg (2 ntsiav tshuaj).

Lub sijhawm ua haujlwm ntawm kev kho thiab qhov ntau npaum li cas yog txiav txim los ntawm tus kws kho mob raws li kev soj ntsuam daim duab ntawm tus kab mob thiab ua tiav cov txiaj ntsig kho tau.

Cov ntaub ntawv tseem ceeb

Hauv cov neeg mob uas muaj lub siab tsis ua hauj lwm hnyav, yuav tsum tau txhaj tshuaj tsawg dua yog xav txog ntawm ib leeg lub siab.

Kev kho mob ntawm cov neeg mob ntshav qis, nrog rau cov neeg mob uas muaj kev pheej hmoo vim tias qhov txo qis yuav ua rau muaj ntshav siab (hemodynamically tseem ceeb stenosis ntawm cov hlab ntsha hlwb, ib daim ntawv hnyav ntawm cov mob plawv), nws raug nquahu kom pib nrog kev noj me me. Hauv cov xwm txheej zoo li no, tsuas yog nce me ntsis hauv koob tshuaj tso cai.

Hauv cov neeg mob uas mob raum tsis ua haujlwm (CC tsawg dua 30 ml / min), qhov tshuaj txhua hnub yog txo rau 600 mg.

Txhais ntawm Wasonite

Kuj tseem muaj ntau lub ntsej muag ntawm Wazonite, uas yog, cov tshuaj uas nws nquag muaj pentoxifylline. Nws yog Ntshoo, AgapurinTrental, Latren, Pentoxifylline thiab lwm tus

Cov qauv ntawm vasonite, tus nqi hauv cov chaw muag tshuaj

Yog tias tsim nyog, koj tuaj yeem hloov Vasonite nrog ib qho tshuaj ntawm cov khoom nquag - cov no yog cov tshuaj:

Thaum xaiv cov tshuaj analogues, nws yog ib qho tseem ceeb kom nkag siab tias cov lus qhia rau kev siv Vazonit 600 mg, tus nqi thiab tshuaj xyuas cov tshuaj nrog cov teebmeem zoo sib xws tsis siv. Nws yog ib qho tseem ceeb kom kws kho mob sab laj thiab tsis txhob hloov pauv cov tshuaj ywj siab.

Tus nqi hauv cov khw muag tshuaj ntawm Russia: Vazonit 600 mg retard 20 ntsiav tshuaj - los ntawm 393 txog 472 rubles, raws li 582 lub tsev muag tshuaj.

Txee lub neej yog 5 xyoos. Muab khaws cia rau qhov kub thiab txias tsis tshaj 25 ° C hauv qhov chaw qhuav thiab tsaus ntuj. Qhov xwm txheej ntawm kev faib tawm los ntawm cov khw muag tshuaj yog daim ntawv yuav tshuaj.

Txoj kev ntsuam xyuas hais li cas?

Feem ntau ntawm kev tshuaj xyuas yog qhov zoo, nrog kev qhia ntawm Vazonit ntsiav tshuaj rau hauv txoj kev kho mob ntawm ntau yam kab mob nrog kev tiv thaiv peripheral ncig, qhov mob ntawm cov neeg mob yog maj mam txhim kho. Tab sis tag nrho cov vascular cov kab mob yog qhov nyuaj los kho thiab xav tau txoj kev kho lub sijhawm ntev nyob hauv kev saib xyuas ntawm tus kws kho mob.

Cov kev xav tsis zoo txog Wazonit 600 mg cuam tshuam nrog kev phiv thiab kev siv tshuaj ntau dhau. Tias yog vim li cas nws yuav tsum yog tus kws kho mob sau tseg, coj mus rau hauv tus account tag nrho cov ntsuas thiab contraindications.

2 kev txheeb xyuas rau "Wazonite 600 mg"

Peb yuav cov tshuaj no rau niam nyob rau ib asthiv. Nws mob stroke tuag tes nrog rau tes tuag tes tuag taw. Lawv tau rov qab los ntawm tsev kho mob nrog rau cov tshuaj no, peb tos kom nws ua haujlwm. Txog rau tam sim no, tsawg kawg qee qhov ntsuas tsis pom.

Pentoxifylline yog qhov pheej yig dua li analogues nrog tib cov ntsiab lus tab sis nrog lub npe txawv