Qhov ntsuam xyuas rau hom ntaus nqi ntshav qab zib hom 2 npaum li cas?

Nws tag nrho yog nyob ntawm cov kabmob tshwj xeeb. Tus nqi li ntawm ob rau ob peb kaum tawm txhiab txhiab rubles. Ntawm no yog ib daim ntawv teev luv ntawm cov kab mob uas tau soj ntsuam ntawm UnionMed:

- insulin thiab hom II.

Tus nqi ntawm kev txheeb xyuas DNA kuj tseem yuav yog nyob ntawm seb muaj pes tsawg tus kabmob tau kawm thiab nthuav dav ntawm kev kawm txog yam.

Kev tshuaj ntsuam caj ces tso cai rau koj txheeb xyuas qhov kev xav ua ntej rau cov kab mob hauv qab no:

• Arterial kub siab,
• Tawg siab
• Atherosclerosis ntawm aorta thiab hlab ntshav hlab ntsha,
• Txoj kev pheej hmoo ntawm kev tuag sai
• Thrombophilia thiab varicose leeg.
• Kev txheeb xyuas ntawm txhua daim npav cardio.

• Hom I ntshav qab zib mellitus (insulin-dependant),
• Mob ntshav qab zib Hom II
• Ntshav qab zib nephropathy nyob rau hom ntshav qab zib hom I.

Kab mob ua pa:

• Bronchial hawb pob,
• Mob raum tsis zoo.

Mob hnyuv plab kab mob:

• Crohn's mob
• Qhov tsis zoo ulcerative mob.

Kab mob ntawm cov pob txha metabolism:

Cov kab mob ua rau koj cov thyroid:

• Mob qog noj ntshav
• Graves tus kab mob
• Tus kab mob autoimmune hypothyroiditis.

• Endometriosis
• Noj niam ntiav mis
• Kev kho mob ntawm cov hlab hlwb overgrowth,
• Ua rau lub plab mob hauv plab,
• Kev nyiam huv huv gestosis,
• Phem Loj Ntshiab,

Kev kuaj mob ntawm tus kab mob ntshav siab yug menyuam loj:

• Huntington Chorea,
• Adrenogenital syndrome (kev tsis txaus siab 21-hydroxylase deficiency),
• Cystic fibrosis,
• Phenylketonuria,
• Duchenne myodystrophy,
• Myotonic dystrophy,
• Martin Bell Syndrome,
• Kev mob hlwb pob txha caj qaum (mob Werdnig-Hoffmann).

Kuaj cov ntawv kuaj mob ntawm chaw kuaj mob ARMED yog qhov kev xaiv zoo

• Peb lub tsev kho mob muaj ntawv lees paub thiab raug lees paub los ua txhua yam kev tshawb fawb uas peb muab rau cov neeg mob,
• Muaj ntawv tso cai kho mob siv tau
• Lub chaw sim tshuaj yog nruab nrog cov khoom siv niaj hnub,
• Kev ntsuas cov txiaj ntsig tau muab nyob rau hauv ib lub sijhawm luv luv thiab yog txiav txim siab los ntawm cov kws kho mob paub,
• Tus neeg mob yuav lav nrog kev lees paub tsis pub lwm tus paub.

Hauv kev kuaj mob ntawm lub chaw kuaj mob "ARMED", koj muaj ntawm koj cov kev pabcuam tag nrho cov kev tshuaj ntsuam thiab kev tshawb nrhiav ntau yam uas tsim nyog rau kev kuaj pom lub sijhawm muaj qee yam kab mob lossis kev hloov pauv:

Xaiv hom kev ntsuas uas koj xav tau.

• Kev tsom xam
• Cov cim ntsuas ntshav qab zib
• Tom qab

Tsom xam kev npaj npaj *

Khoom siv sijhawm lub sijhawm *

Lub sij hawm xa tawm *

Ntshaw thaum sawv ntxov, ntawm ib qho kev npliag plab

7 a.m. - 2 teev tsaus ntuj Sat 7 a.m. - 12 p.m. tshav. 8 a.m. - 11 a.m.

Hnub xa cov khoom siv roj ntsha ntawm 16: 00-19: 00, tshwj tsis yog hnub Saturday thiab Hnub Sunday

7 a.m. - 2 teev tsaus ntuj Sat 7 a.m. - 12 p.m. tshav. 8 a.m. - 11 a.m.

Hnub xa cov khoom siv roj ntsha ntawm 16: 00-19: 00, tshwj tsis yog hnub Saturday thiab Hnub Sunday

7 a.m. - 12 teev tsaus ntuj 7 a.m. - 10 a.m.

Hnub xa cov khoom siv roj ntsha ntawm 16: 00-19: 00, tshwj tsis yog hnub Saturday thiab Hnub Sunday

7 a.m. - 12 teev tsaus ntuj 7 a.m. - 11 a.m. tiv tshav. 8 a.m. - 11 a.m.

Hnub ntawm kev xa khoom ntawm biomaterial tom qab 6 teev, tsuas yog Hnub Saturday thiab Hnub Sunday

7 a.m. - 12 teev tsaus ntuj 7 a.m. - 11 a.m. tiv tshav. 8 a.m. - 11 a.m.

Hnub xa cov khoom siv roj ntsha ntawm 16: 00-19: 00, tshwj tsis yog hnub Saturday thiab Hnub Sunday

7 a.m. - 12 teev tsaus ntuj 7 a.m. - 11 a.m. tiv tshav. 8 a.m. - 11 a.m.

Hnub ntawm kev xa khoom ntawm biomaterial tom qab 6 teev, tsuas yog Hnub Saturday thiab Hnub Sunday

Ntshaw thaum sawv ntxov, ntawm ib qho kev npliag plab

7 a.m. - 6.30 p.m. Sat 7 a.m. - 1 teev tsaus ntuj. 8 a.m. - 11 a.m.

Hauv 12 hnub ua haujlwm

Ntshaw thaum sawv ntxov, ntawm ib qho kev npliag plab

7 a.m. - 12 teev tsaus ntuj 7 a.m. - 11 a.m.

Hauv 14 hnub ua haujlwm

* Qhia meej lub sijhawm thiab cov xwm txheej ntawm cov qauv khoom siv rau kev tshawb fawb thiab kev tshaj tawm hauv cov ceg hauv xov tooj +7 (861) 205-02-02.

** Hauv cov poj niam cev xeeb tub, qhov kev kawm no tau ua kom txog rau 28 lub lim tiam ntawm cev xeeb tub.

Kuaj ntshav Qab zib

Cov zej zog kev kho mob niaj hnub pom zoo kom kuaj ntshav qab zib hauv qee pawg neeg. Ua ntej tshaj plaws, nws yog qhov tsim nyog rau cov neeg uas tau nce mus txog 45 xyoos lossis ntau dua. Yog tias qhov txiaj ntsig tsis zoo, kev ntsuam xyuas yog nqa tawm txhua peb lub xyoos.

Cov neeg mob uas hnub nyoog yau yuav tsum ua cov txheej txheem nrog:

• thawj
• coj muaj keeb,
• haiv neeg lossis pawg neeg ntawm ib pab pawg,
• mob ntshav qab zib gestational
• ntshav siab
• cov me nyuam yug hnyav dua 4.5 kg,
• siab glycemia ntawm lub plab khoob.

Txog kev soj ntsuam kev ua haujlwm nruab nrab thiab hauv nruab nrab, nws raug pom zoo los txiav txim siab txog qib piam thaj thiab hemoglobin A1c. Qhov no yog hemoglobin, qhov uas cov kua nplaum nyob hauv qab nrog cuam tshuam nrog hemoglobin molecule.

Glycosylated hemoglobin cuam tshuam nrog cov ntshav piam thaj. Nws ua raws li qhov taw qhia ntawm theem ntawm cov khoom noj metabolism hauv peb lub hlis ua ntej kev txheeb xyuas. Tus nqi ntawm HbA1c tsim yog nyob ntawm lub siab ntawm hyperglycemia. Kev kho kom yooj yim ntawm nws qib hauv cov ntshav tshwm sim 4-5 lub lis piam tom qab euglycemia.

Tus nqi ntawm HbA1c yog txiav txim siab yog tias nws yuav tsim nyog los tswj cov metabolism hauv kev ua kom yuag thiab paub meej tias nws cov nyiaj them rov qab rau cov neeg mob ntshav qab zib uas tau mob ntev.

Kev kuaj mob nta

Txhawm rau txhawm rau txheeb xyuas thiab ua tiav kev soj ntsuam ntawm tus kab mob, koj yuav tsum dhau los ntawm ntau cov txheej txheem kuaj mob.

Ua ntej tshaj plaws, cov no yog cov ntawv tshawb pom nyob hauv cov laus, uas yog kev kawm txog cov piam thaj los ntawm kev kuaj cov zis thiab ntshav, nrog rau kev sim rau ketones thiab kev kuaj ntshav qabzib.

Ib qho ntxiv, kev tshuaj ntsuam yog kwv rau:

1. HbA1c,
2. fructosamine
3. microalbumin,
4. tso zis creatinine
5. lipid profile.

Muaj ib qho kev soj ntsuam ntxiv ntawm kev tshawb fawb txog ntshav qab zib, uas ua rau nws tuaj yeem tswj hwm kev txhim kho ntshav qab zib, cov lus txhais no:

• C peptide
• cov tshuaj tiv thaiv rau cov tshuaj insulin
• tshuaj tiv thaiv rau islets ntawm Langengars thiab tyrosine phosphatase,
• glutamic acid decarboxylase cov tshuaj tiv thaiv,
• ghrelin, raschistina, leptin, adiponectin,
• HLA ntaus ntawv.

Txhawm rau txiav txim siab pathology rau ob peb xyoo lawm, cov kws kho mob pom zoo ua ib qho kev soj ntsuam ntawm cov piam thaj sai. Xyoo tsis ntev los no, nws tau pom tias muaj kev sib txuam ntau dua ntawm cov ntshav qab zib cov ntshav, kev vascular kev tsis txaus ntseeg thiab lawv qib kev loj hlob, nws pom tsis yog nrog kev yoo qab zib, tab sis nrog nws cov qib nce tom qab noj mov. Qhov no yog hu ua postprandial hyperglycemia.

Txhua tus ntaus cim ntawm ntshav qab zib hom 1 tuaj yeem faib raws li hauv qab no:

1. caj ces
2. tshuaj tiv thaiv kab mob
3. metabolic.

HLA ntaus ntawv

Mob ntshav qab zib mellitus, raws li lub tswv yim ntawm cov tshuaj niaj hnub, muaj qhov pib mob hnyav, tab sis lub sijhawm ntev mus ntev. Rau rau qib paub hauv kev tsim cov kab mob no. Thawj thawj ntawm cov no yog theem ntawm kev mob tshwm sim los yog tsis muaj cov noob caj noob ces cuam tshuam nrog ntshav qab zib hom 1.

Nws yog tsim nyog taw qhia tias qhov muaj ntawm HLA antigens, tshwj xeeb ntawm chav kawm thib ob: DR 3, DR 4, DQ, yog qhov tseem ceeb. Txoj kev pheej hmoo ntawm pathology tsim nyob rau hauv cov ntaub ntawv no nce ntau zaus. Tam sim no, ib qho keeb kwm kab mob rau cov tsos ntawm cov kab mob ntawm thawj hom tau suav hais tias yog kev sib txuas ntawm ob peb lub cev sib txawv ntawm cov ib txwm muaj.

Cov cim ntaus cim tshaj plaws rau hom 1 yog HLA antigens. Tus yam ntxwv haplotypes uas yog yam ntxwv ntawm tus kabmob ntshav qab zib hom 1 pom nyob hauv 77% ntawm cov neeg mob ntshav qab zib. 6: muaj haplotypes uas pom tau tias tiv thaiv.

Tshuaj tua kab mob rau Langerhans Islet Cell

Vim tias kev tsim cov autoantibodies mus rau lub hlwb ntawm cov islets ntawm Langerhans, tom kawg tau raug rhuav tshem, uas ua rau lub cev tsis muaj zog ntawm cov tshuaj lom neeg thiab ua kom pom cov duab ntawm cov ntshav qab zib hom 1.

Xws li cov tshuab yuav raug txiav txim caj los sis tshwm sim vim los ntawm ntau yam.

Ntawm cov feem ntau muaj:

• kab mob kis
• lom ntsiab
• ntau yam kev ntxhov siab.

Tus kab mob ntawm thawj hom yog cim los ntawm theem ntawm kev mob ntshav qab zib uas tsis muaj tsos mob, nws tuaj yeem kav mus ntau xyoo. Qhov kev ua kom sib xyaw thiab tso pa tawm ntawm cov kua dej hauv lub sijhawm no tsuas yog tuaj yeem pom los ntawm kev kawm txog cov kua nplaum nyob nruab nrab.

Hauv cov tshuaj, muaj mob ntawm kev kuaj pom ntawm cov tshuaj tiv thaiv li yim xyoo lossis ntau xyoo ua ntej qhov pib ntawm kev saib xyuas cov duab hauv tus neeg mob. Lub ntsiab lus ntawm cov tshuaj tiv thaiv kab mob yuav tsum tau siv los ua kev kuaj mob thaum ntxov ntawm hom 1 ntshav qab zib.

Hauv cov neeg muaj cov tshuaj tiv thaiv zoo li no, islet cell ua haujlwm poob qis, uas yog pom los ntawm kev ua txhaum ntawm cov tshuaj insulin zais cia. Yog hais tias lub sij hawm ua tiav pov tseg, tom qab ntawv soj ntsuam symptomatology ntawm ntshav qab zib ntawm ntau yam no tshwm sim.

Ntau cov kev tshawb fawb qhia tias cov tshuaj tiv thaiv kab mob no muaj nyob rau hauv 70% ntawm cov neeg teb nrog tus mob ntshav qab zib hom 1 nyuam qhuav tshwm sim tshiab. Hauv kev tswj hwm cov tsis mob ntshav qab zib pawg, muaj tsuas yog 0.1-0.5% ntawm cov kis ntawm cov tshuaj tiv thaiv.

Cov tshuaj tiv thaiv kab mob no tseem tuaj yeem nrhiav pom hauv cov txheeb ze ntawm tus mob ntshav qab zib. Cov pab pawg ntawm cov neeg no muaj lub siab nrog qhov tshwm sim. Ntau cov kev tshawb fawb qhia pom tias cov txheeb ze uas muaj cov tshuaj tiv thaiv kab mob ntshav qab zib hom 1 nyob rau sijhawm.

Cov cim ntawm qee hom mob ntshav qab zib hom 2 mob ntshav qab zib kuj tseem suav nrog qhov kev kawm no. Cov kws tshawb fawb tau ua pov thawj tias kev txiav txim siab theem ntawm cov tshuaj tiv thaiv kab mob hauv cov ntshav qab zib muaj hom mob thib ob pab kom pom tseeb nws txawm tias ua ntej cov duab hauv chaw kho mob tshwm sim, thiab pab txhawb kev teeb tsa cov tshuaj tiv thaiv kab mob insulin. Yog li, hauv cov neeg mob ntshav qab zib nrog hom mob thib ob, nws muaj peev xwm twv seb kev tsim cov kev vam khom ntxiv ntawm cov tshuaj insulin.

Tshuaj tua kab mob rau cov tshuaj insulin muaj nyob hauv kwv yees li 40% ntawm cov neeg muaj ntshav qab zib hom 1. Muaj kev xav ntawm kev sib txheeb ntawm cov tshuaj tiv thaiv rau cov tshuaj insulin thiab cov tshuaj tiv thaiv rau islet cells.

Lub qub yuav nyob rau theem ntawm kev mob ntshav qab zib thiab nrog rau qhov pib ntawm cov tsos mob ntawm tus mob ntshav qab zib hom 1.

Glutamic acid decarboxylase

Tsis ntev los no, cov kws tshawb fawb tau txheeb xyuas lub ntsiab antigen, uas yog lub hom phiaj rau autoantibodies uas cuam tshuam nrog kev tsim cov tshuaj insulin-tiv thaiv mob ntshav qab zib. Nws yog decarboxylase ntawm glutamic acid.

Cov kua qaub no yog cov enzyme membrane uas biosynthesizes tus neurotransmitter ntawm lub hauv nruab nrab cov hlab hlwb - gamma-aminobutyric acid. Qhov enzyme tau pom thawj zaug hauv cov neeg muaj teeb meem ntawm lub paj hlwb poob siab.

Tshuaj tua kab mob rau GAD yog qhov kev ntaus cim tshaj plaws rau kev kuaj pom cov mob ntshav qab zib. Yog li, qhov kev pheej hmoo siab ntawm kev tsim cov ntshav qab zib hom 1 tuaj yeem txheeb tau. Nrog kev tsim cov asymptomatic ntawm tus kab mob no, cov tshuaj tiv thaiv mus rau GAD tuaj yeem kuaj pom hauv tib neeg xya xyoo ua ntej pom qhov tseeb ntawm tus kab mob.

Cov neeg ntseeg siab tshaj plaws thiab cov ncauj lus ntawm cov kws tshawb fawb tau suav hais tias yog kev tsom xam ua ib txhij ntsuas ntawm ntau lub cim hauv cov ntshav. 1 tus cim sawv cev rau 20% ntawm cov ntaub ntawv, ob lub cim taw qhia 44% ntawm cov ntaub ntawv, thiab peb tus cim sawv cev 95% ntawm cov ntaub ntawv.

Cov Cim Ntshav Qab Zib Autoimmune

Hauv cov ntshav qab zib, qhov profile ntawm autoantibodies yog nyob ntawm poj niam txiv neej thiab hnub nyoog. Cov tshuaj tua kab mob ua rau antigens thiab tshuaj tiv thaiv rau islet cells, raws li txoj cai, yog nyob hauv cov menyuam yaus dua li cov neeg laus. Cov tshuaj tua kab mob rau glutamic acid decarboxylase, feem ntau, pom hauv cov poj niam.

Qhov kev xav ua ntej rau kev tsim qee yam sib txawv ntawm cov kab mob autoantibodies feem ntau yuav txiav txim siab los ntawm cov caj ces sib txawv ntawm HLA, vim hais tias autoantibodies rau insulin, islet hlwb thiab islet antigen 2 feem ntau pom muaj nyob hauv cov neeg uas muaj HLA - DR 4 / DQ 8 (DQA 1 * 0301 / DQB 1 * 0302). Nyob rau tib lub sijhawm, tshuaj tiv thaiv rau glutamic acid decarboxylase muaj nyob hauv cov neeg muaj HLA genotypes - DR 3 DQ 2 (DQA 1 * 0501 / DQB 1 * 0201).

Ntau hom kab mob autoantibodies feem ntau muaj nyob rau ntawm cov neeg mob ntshav qab zib, thaum cov neeg muaj tus mob ntshav qab zib ua lub cev muaj ntshav qab zib muaj tsuas yog ib hom mob autoantibody.

Cov tshuaj tua kab mob rau glutamic acid decarboxylase yog ntawm cov neeg mob ntshav qab zib nrog thawj hom pathology, tab sis kuj tseem muaj tus mob siab rau cov neeg uas muaj phenotypes ntawm yam thib ob ntawm tus kab mob.

Kev txiav txim siab ntawm cov tshuaj tiv thaiv no ua rau nws muaj peev xwm txheeb xyuas ntau qhov xwm txheej ntawm autoimmunity, yog tias qhov no tsuas yog cim rau cov neeg laus.

Kev tsom xam nqi

Cov neeg uas xav tias muaj ntshav qab zib feem ntau txaus siab nyob rau hauv ntau npaum li cas cov kev ntsuas mob ntshav qab zib npiav cim cov nqi. Muaj qee qhov profiles uas tau hais tawm los ntawm ntau cov khoom siv tshuaj ntsuam.

Ib qho kev sim dav dav hu ua kev tswj ntshav qab zib muaj xws li kuaj ntshav qab zib thiab creatinine.

Tsis tas li, cov profile muaj:

1. tsom xam hemoglobin tshuaj,
2. triglycerides
3. tag nrho cov roj (cholesterol)
4. Roj HDL,
5. LDL roj,
6. tso zis albumin
7. homocestein,
8. Reberg xeem,
9. piam thaj hauv cov zis.

Tus nqi ntawm xws li cov kev tsom xam muaj kwv yees li 5 txhiab rubles.

Kev soj ntsuam suav nrog:

1. ntshav qabzib tsom
2. glycated hemoglobin.

Tus nqi tshuaj ntsuam yog kwv yees li 900 rubles.

• cov tshuaj tiv thaiv rau cov tshuaj insulin
• tshuaj tiv thaiv kom tyrosine phosphatase.
• glutamate decarboxylase cov tshuaj tiv thaiv,
• tshuaj tiv thaiv kom tyrosine phosphatase.

Qhov kev tshawb xyuas no yuav raug nqi txog li 4 txhiab rubles.

Qhov kev kuaj ntshav ntawm cov tshuaj insulin yuav raug nqi li 450 rubles, kev kuaj C-peptide yuav raug nqi 350 rubles.

Kev kuaj mob thaum cev xeeb tub

Kev kuaj ntshav qab zib yog kuaj hauv plab tas. Qhov taw qhia ntawm 4.8 mmol / los ntawm tus ntiv tes thiab 5.3 - 6.9 mmol / l los ntawm cov leeg ntshav yuav ua rau muaj kev txhawj xeeb. Ua ntej xeem ntsuas, tus poj niam yuav tsum tsis txhob noj zaub mov ntev li 10 teev.

Thaum xeeb tus me nyuam hauv plab, kuaj ntshav qabzib tuaj yeem ua. Rau qhov no, tus poj niam haus 75 g ntawm cov piam thaj hauv ib khob dej. Tom qab 2 teev, kuaj ntshav rov ua dua. Ua ntej kev txheeb xyuas, koj tsis tas yuav txwv koj tus kheej hauv kev noj haus. Cov khoom noj yuav tsum paub txog.

Yog tias pom cov tsos mob ntshav qab zib, koj yuav tsum tsis txhob laug sib tham nrog koj tus kws kho mob. Txheeb xyuas tus kab mob thaum ntxov yuav pab tau tiv thaiv tus mob thiab kev loj hlob ntawm lub neej muaj teeb meem. Cov txiaj ntsig kev tshawb fawb yuav tsum yog qhov tseeb, rau qhov no koj yuav tsum ua raws txhua txoj cai ntawm kev npaj rau kev tsom xam.

Kev kuaj ntshav qab zib li cas qhia tus kws tshaj lij hauv cov yeeb yaj kiab hauv tsab xov xwm no.