Lub luag haujlwm ntawm glucophage hauv kev kho mob ntawm hom 2 mob ntshav qab zib

Luam tawm hauv phau ntawv journal:
Tus Kab Mob Khees Xog Vol. 18, No. 10, 2010

Cov Ph.D. I.V. Kononenko, xibfwb O.M. Smirnova
Tsoomfwv Meskas Lub Chaw Haujlwm Kev Tshawb Fawb Kev Tshawb Nrhiav Kev Kawm Qib Siab, Moscow

Ntshav qab zib Hom 2 yog ib hom mob ntev mus ntev uas ua rau muaj tus kabmob hyperglycemia, uas yog qhov tshwm sim ntawm kev tsis txaus siab nyob rau hauv kev zais thiab kev ua haujlwm ntawm cov tshuaj insulin. Nov yog tus mob hnyav, mob nyhav thiab tas mus li. Kev tsis pom qhov tsis zoo nyob hauv cov neeg mob uas muaj hom 2 mob ntshav qab zib mellitus (hom ntshav qab zib 2) yog txiav txim siab los ntawm kev txhim kho ntawm macro- thiab microvascular cov teeb meem. Qhov ua rau mob macrovascular yog atherosclerotic lesion ntawm cov hlab ntsha tseem ceeb, ua rau txoj kev txhim kho cov hlab plawv thiab nws cov teeb meem nyuaj, kab mob cerebrovascular thiab obliterating qhov txhab ntawm cov hlab ntsha ntawm qhov qis qis. Cov teeb meem microvascular raws li kev puas tsuaj tshwj xeeb ntawm microvasculature, tshwj xeeb rau ntshav qab zib, txuam nrog cov tuab ntawm cov hlab ntsha hauv capillary. Cov kab mob soj ntsuam ntawm microangiopathy yog mob ntshav qab zib nephropathy thiab retinopathy. DM yog qhov ua rau ntau yam dig muag ntawm cov laus. Lub hom phiaj ntawm kev kho ntshav qab zib yog los normalize glycemia thiab txo kev pheej hmoo ntawm loj heev- thiab cov teeb meem microvascular. Cov teeb meem pheej hmoo tseem ceeb tshaj plaws cuam tshuam rau kev txhim kho cov hlab plawv mob hauv cov neeg mob ntshav qab zib hom 2 yog lub xeev ntawm cov metabolism hauv cov metabolism, cov ntshav siab thiab lipid spectrum ntawm ntshav ntshav. Cov lus 1 qhia txog cov txiaj ntsig tseem ceeb ntawm cov cim tseem ceeb, kev ua tiav ntawm kev ua kom muaj kev ua tau zoo ntawm kev kho mob ntawm cov neeg mob ntshav qab zib hom 2.

Cov lus 1. Kev tswj cov kab mob (cov hom phiaj kho) rau hom 2 mob ntshav qab zib mellitus (Cov qauv txheej txheem rau kev saib xyuas tshwj xeeb rau cov neeg mob ntshav qab zib mellitus, 2009)