Kev sib xyaw rau kev quav dej cawv: daim ntawv thov
Unitiol muaj nyob rau hauv daim ntawv ntawm kev daws teeb meem rau kev tswj hwm intramuscular thiab subcutaneous: ntshiab, pinkish lossis tsis muaj kob, nrog me ntsis hydrogen sulfide tsw (5 ml hauv iav ampoules, 5 ampoules hauv blister pob, 2 pob hauv ib pob ntawv ci).
Cov lus sib xyaw ntawm 1 ml ntawm cov tshuaj:
- cov tshuaj nquag: unitiol (dimercaptopropanesulfonate sodium monohydrate) - 50 mg,
- Cov khoom ua haujlwm pabcuam: sulfuric acid 0.1 M, Trilon B (disodium edetate), dej rau kev txhaj tshuaj.
Tsuas tshuaj thiab tswj hwm
Unitiol raug muab tshuaj intramuscularly lossis subcutaneously.
- arsenic lom: 5-10 ml (5 mg rau 1 kg ntawm lub cev qhov hnyav) 3-4 zaug rau thawj hnub, 2-3 zaug rau hnub thib ob thiab 1-2 zaug ntawm hnub tom qab,
- lom neeg mob mercury: raws li cov txheej txheem saum toj no, rau 6-7 hnub (kom txog thaum cov tsos mob ntawm intoxication ploj),
- mob ntshav glycoside lom: 5-10 ml ntawm cov tshuaj 5% aqueous ntawm cov tshuaj 3-4 zaug ib hnub rau thawj ob hnub, tom qab ntawd 5-10 ml 1-2 zaug ib hnub (txog thaum cov txiaj ntsig cardiotoxic ploj mus),
- nyem ntawm delirium: 4-5 ml ntawm Unithiol ib zaug,
- Wilson-Konovalov's mob: 5-10 ml ntawm 5% aqueous tov intramuscularly 1 zaug hauv ib hnub txhua hnub lossis txhua lwm hnub, 25-30 kev txhaj tshuaj yog qhov xav tau rau ib chav kho mob, yog tias tsim nyog, chav kawm tau rov ua dua tom qab 3-4 lub hlis,
- cawv ntev ntev: 3-5 ml 2-3 zaug ib lub lim tiam.
Unitiol: tus nqi hauv cov khw muag tshuaj online
UNITIOL 5% 5ml 10 pcs. txhaj tshuaj siv
Unitiol 50 mg / ml tov rau cov tshuaj intramuscular thiab subcutaneous ntawm 5 ml 10 pcs.
Unitiol 50 mg / ml tov rau cov tshuaj intramuscular thiab subcutaneous ntawm 5 ml 10 pcs.
Cov ntaub ntawv hais txog cov tshuaj raug muab dav dav, muab rau kev qhia tawm thiab tsis hloov chaw cov lus qhia. Kev siv tshuaj rau tus kheej yog qhov txaus ntshai rau kev noj qab haus huv!
Hauv tebchaws Askiv, muaj txoj cai lij choj raws li uas tus kws phais neeg tuaj yeem tsis kam ua haujlwm rau tus neeg mob yog tias nws haus luam yeeb lossis rog dhau. Ib tus neeg yuav tsum tso tawm tus cwj pwm tsis zoo, thiab tom qab ntawd, tej zaum, nws yuav tsis xav tau kev phais mob.
Ntau lab tus kab mob tau yug, ciaj thiab tuag hauv peb lub plab. Lawv tuaj yeem pom tsuas yog txhawb nqa siab, tab sis yog tias lawv tuaj ua ke, lawv yuav haum rau hauv lub khob kas fes.
Qhov ua kom pom kev vibrator ua ntej nyob rau xyoo 19th. Nws ua haujlwm ntawm lub tshuab tso hluav taws xob thiab nws tau npaj kho qhov mob poj niam.
Hauv kev mob siab kom tau tus neeg mob tawm, cov kws kho mob feem ntau mus deb dhau. Yog li, piv txwv li, qee yam Charles Jensen nyob rau lub sijhawm txij xyoo 1954 txog 1994. muaj sia nyob ntau dua 900 lub neoplasm tshem tawm txoj haujlwm.
Ntau tshaj $ 500 lab tau ib xyoo yog siv rau cov tshuaj tiv thaiv ua xua nkaus xwb nyob hauv Tebchaws Meskas. Koj puas tseem ntseeg tias txoj hauv kev uas thaum kawg kov yeej kev ua xua yuav pom?
Thaum cov neeg nyiam hnia, lawv ib leeg poob 6.4 kcal ib feeb, tab sis tib lub sijhawm lawv sib pauv yuav luag 300 ntau hom kab sib txawv.
Tib neeg cov pob txha yog plaub zaug muaj zog dua li cov pob zeb.
Tib neeg cov ntshav "khiav" los ntawm cov hlab ntsha hauv qab qhov siab, thiab yog tias nws txoj kev ncaj ncees tau ua txhaum, nws tuaj yeem tua txog 10 meters.
Qhov nruab nrab lub neej ntawm cov laug yog tsawg dua ntawm txoj cai.
Muaj 74 xyoo nyob hauv tebchaws Australian yawg James Harrison tau los ua neeg muab ntshav li 1,000 zaus. Nws muaj ib hom ntshav uas tsis tshua muaj, cov tshuaj tiv thaiv uas pab cov menyuam mos liab uas muaj ntshav tsawg txaus kom ciaj sia taus. Yog li, Australian thiaj cawm tau ntau txog ob lab tus menyuam.
Cov tshuaj hnoos "Terpincode" yog ib tus thawj coj hauv kev muag, tsis muaj vim tias nws muaj tshuaj.
Yog tias koj luag nyav tsuas yog ob zaug ib hnub, koj tuaj yeem txo cov ntshav siab thiab txo qhov kev pheej hmoo ntawm lub plawv thiab mob nkees.
Nws tau siv los ua yawning enriches lub cev nrog oxygen. Txawm li cas los xij, qhov kev pom no tau nthuav dav. Cov kws tshawb fawb tau ua pov thawj tias yawning, ib tus neeg ua kom lub hlwb txias thiab txhim kho kev ua haujlwm.
Ntau cov tshuaj tau xub pib ua lag luam li tshuaj. Piv txwv li yeeb dawb, tau pib ua lag luam ua tshuaj hnoos. Thiab cocaine tau pom zoo los ntawm cov kws kho mob ua tshuaj loog thiab yog lub zog ntawm kev ua kom lub siab ntev.
Kev ua haujlwm uas ib tus neeg tsis nyiam yuav muaj kev phom sij rau nws lub siab ntau dua li qhov uas tsis muaj haujlwm hlo li.
Txhua tus tuaj yeem ntsib cov xwm txheej uas nws plam hniav. Nov yog txheej txheem ib txwm ua los ntawm kws kho hniav, los yog ua rau raug mob. Hauv txhua thiab.
Daim ntawv tso tawm
Cov kua roj ntshiab thiab tsis muaj xim.
- 5 ml ntawm xws li kev daws teeb meem nyob rau hauv ampoule, 10 ampoules hauv ib pob ntawm cardboard.
- 5 ml ntawm xws li kev daws teeb meem nyob rau hauv ampoule, 100 lossis 75 ampoules hauv daim ntawv thawv.
- 5 ml ntawm xws li kev daws teeb meem nyob rau hauv ampoule, 10 ampoules hauv ib lub hlwv pob - ob, kaum tsib lossis nees nkaum pob hauv ib thawv ntawv.
Pharmacodynamics thiab pharmacokinetics
Cov Tshuaj Hauv Tshuaj
Unitiol muaj Kev tso detoxification ntawv. Tshem tawm qhov tsis zoo sulfhydryl pawgCov. Raws li hom kev txiav txim, nws yog nyob ze rau complexones. Sulfhydryl pawg hnov mob nrog thiol lom nyob rau hauv cov ntaub so ntswg thiab hauv cov ntshav, tsim kev lom zem rau cov nyom uas tso nrog cov zis. Kev thaiv cov tshuaj lom rov qab ua kom rov ua haujlwm ntawm cov kab mob enzyme hauv hlwb cuam tshuam los ntawm cov tshuaj lom neeg. Nws yog siv ua tshuaj tiv thaiv rau kev lom. hnyav hlau, arsenic thiab lawv cov sib txuas.
Hauv cov neeg uas muaj theem nrab amyloidosis thiab polyneuropathy ntawm ntshav qab zib keeb kwm pab txo qis qhov mob, txhim kho kev ua haujlwm ntawm lub paj hlwb, tswj kev capillary permeability.
Cov Tshuaj Pharmacokinetics
Tom qab txhaj, cov tshuaj lwg me me koom tes rau hauv cov ntshav. Qhov siab tshaj plaws nyob rau hauv cov ntshav yog sau cia ib nrab teev tom qab txhaj tshuaj intramuscular. Qhov kev tshem tawm ib nrab-lub neej ncav 2 teev. Nws yog tawm hauv cov zis, tsuas yog nyob rau hauv daim ntawv ntawm cov khoom ntawm tsis tiav oxidation.
Kev ntsuas rau siv
- hepatocerebral dystrophy (Wilson-Konovalov mob),
- qaug cawvmuaj mercury, arsenic, chromium, bismuthlossis mob glycosides,
- ntawm quav cawv hom mob thiab dej cawv txiv cawvraws li ib feem ntawm txoj kev kho mob.
Cov Yuav Tsum Tau Ua
- daim siab ua hauj lwm,
- xob deevrau cov tshuaj
- hnub nyoog txog 18 xyoo
- cev xeeb tub lossis kev pub mis,
- leeg ntshav siab.
Cov lus qhia rau kev siv Unithiol (Txuj ci thiab ntau npaum li cas)
Cov lus qhia rau kev siv Unithiol tshuaj tawm los tswj cov tshuaj intramuscularly lossis subcutaneously.
Hauv kev kho mob arsenic toxicity cov tshuaj yog muab rau tus nqi ntawm 50 mg ntawm cov tshuaj nquag rau 10 kg ntawm qhov hnyav (250-500 mg), nyob rau thawj hnub nws raug qhia kom tswj hwm qhov tshuaj zoo li no 4 zaug, nyob rau hnub thib ob - txog 3 zaug, nyob rau hnub tom qab - ib hnub ib zaug.
Hauv kev kho mob lom nrog mercury ntsev cov tshuaj yog siv raws li cov txheej txheem saum toj no rau ib lub lim tiam lossis txog thaum cov tsos mob ploj mus.
Hauv kev kho mob mob caj dab glycoside lom nyob rau thawj hnub thiab thib ob, cov tshuaj tau muab rau tus nqi ntawm 50 mg ntawm cov tshuaj nquag rau 10 kg ntawm qhov hnyav (250-500 mg) txog plaub zaug hauv ib hnub, nyob rau hnub tom qab - ob zaug ib hnub kom txog thaum cov tsos mob ploj. cardiotoxicity.
Hauv kev kho mob hepatocerebral dystrophy nws raug qhia kom txhaj tshuaj intramuscularly 5-10 ml ntawm ib qho kev siv tshuaj txheem (50 mg / ml) txhua hnub lossis txhua ob hnub, sijhawm kho yog feem ntau 26-30 hno, yog tias tsim nyog, chav kawm ntawm txoj kev kho yog rov qab tom qab 4 lub hlis.
Kev haus cawv rau cov dej cawv
Hauv kev kho mob haus cawv ntev zuj zus 4-5 ml ntawm kev siv tshuaj txheem ib qho tshuaj yog muab txog li peb zaug hauv ib as thiv.
Thaum kho delirium 5 ml ntawm qhov kev ntsuas txheem txheem yog txhaj ib zaug.
Cov lus qhia tshwj xeeb
Hauv kev kho mob ntawm kev mob hnyav, cov tshuaj yog kws kho nrog rau cov txheej txheem kev kho ntxiv: kev kho oxygen, kev kho plab, tso tshuaj Dextrose.
Unitiol-Binergia, R-X-1, Unitiol-Ferein, Zorex.
Siv tsis tau rau cov neeg muaj hnub nyoog 18 xyoo rov hauv.
Yuav siv li cas: noj ntau thiab hom tshuaj kho
V / m, s / c. Nrog rau cov tshuaj ua kom tsis haum arsenic - 250-500 mg ntawm cov tshuaj (5-10 ml ntawm 5% kua aqueous), ntawm tus nqi 0.05 g / 10 kg, nyob rau thawj hnub - 3-4 zaug, nyob rau hnub thib ob - 2-3 zaug, nyob rau hnub tom ntej - 1-2 zaug. Thaum muaj tshuaj lom nrog Hg sib txuas - raws li cov qauv qub rau 6-7 hnub. Txoj kev kho yog nqa tawm kom txog thaum cov tsos mob ntawm intoxication ploj. Nrog digitalis intoxication, 250-500 mg (5-10 ml ntawm 5% kua aqueous) tau muab 3-4 zaug ib hnub hauv thawj 2 hnub, tom qab ntawv 1-2 zaug hauv ib hnub kom txog thaum cov txiaj ntsig cardiotoxic nres. Nrog rau hepatocerebral dystrophy - IM 250-500 mg (5-10 ml ntawm 5% kev daws) txhua hnub lossis txhua lwm hnub, chav kawm ntawm kev kho mob - 25-30 hno, yog tias tsim nyog, rov ua dua tom qab 3-4 lub hlis. Hauv cov cawv cawv ntev ntev, 150-250 mg (3-5 ml ntawm 5% kev daws) yog kho 2-3 zaug hauv ib lub lis piam. Rau kev txiav cov delirium - ib zaug 200-250 mg (4-5 ml ntawm 5% kev daws). Hauv kev mob ntshav qab zib polyneuropathy - iv, 250 mg (5 ml ntawm 5% kev daws), chav kawm ntawm kev kho mob yog 10 hnoos.
Sab hauv, 30 feeb ua ntej noj mov, nrog dej me me.
Cawv tshem tawm tus mob cawv, lom nrog As sib xyaw thiab ntsev ntawm cov hlau loj: 250-500 mg (1-2 tsiav tshuaj) ib hnub, yog tias tsim nyog, qhov koob tshuaj tuaj yeem raug nce ntxiv rau 750 mg (3 tsiav tshuaj) ib hnub, muab faib ua ob peb zaug tshuaj. Txoj kev kho yog nqa tawm kom txog thaum cov tsos mob ntawm intoxication tsum.
Kev haus cawv mus ntev: 500 mg ntawm cov tshuaj (2 tsiav tshuaj) 2 zaug ib hnub twg ua ib feem ntawm txoj kev kho mob.
Mob ntshav qab zib polyneuropathy: 250 mg (1 tshuaj ntsiav) ib hnub rau 10 hnub.
Pharmacological kev txiav txim
Qhov tshwj xeeb ua tus sawv cev, muaj cov nyhuv detoxifying. Active sulfhydryl pawg, sib cuam tshuam nrog thiol cov tshuaj lom thiab tsim cov tshuaj lom neeg tsis muaj tshuaj lom nrog lawv, rov ua lub luag haujlwm ntawm cov kab mob enzyme ntawm lub cev cuam tshuam los ntawm tshuaj lom. Nce kev tshaj tawm ntawm qee qhov kev suav (tshwj xeeb tshaj yog Cu2 + thiab Zn2 +) los ntawm cov hlau uas muaj cov cell enzymes.
Hauv kev mob ntshav qab zib polyneuropathy, nws txo cov kev mob tsis xis nyob, txhim kho cov kev mob ntawm cov hlab ntsha hlwb thiab ua kom lub zog tsis haum ntawm capillaries.
Kev piav qhia ntawm cov tshuaj thiab nws muaj pes tsawg leeg
"Unithiol" yog cov tshuaj uas siv dav hauv toxicology. Ua tsaug rau nws lub zog, nws pab lub cev tiv thaiv nrog kev lom, tshem tawm cov tshuaj lom muaj kuab lom los ntawm nws.
Cov tshuaj yog tsim tawm hauv txoj hauv kev daws, uas yog npaj rau kev taw qhia rau hauv cov leeg nqaij los yog hauv qab daim tawv. Unitiol yog tshuaj tiv thaiv kab mob. Thaum cov tshuaj nkag mus rau hauv lub cev, nws pib cuam tshuam nrog co toxins. Nws txuas rau lawv, hloov lawv mus rau qhov chaw nyab xeeb uas tsis muaj kev hem thawj rau tib neeg, thiab tshem lawv tawm ntawm lub cev.
Cov tshuaj muaj nyob hauv ampoules, hauv txhua qhov ntawm 5 millilitic ntawm kev daws. Nws suav nrog:
Siv cov tshuaj kom quav cawv
“Unitiol” rau kev haus cawv yog muaj ntau yam. Dua li ntawm qhov no, nws tsis yog txoj kev kho mob tseem ceeb rau qhov teeb meem no, thiab tsis ua rau muaj lub siab xav haus cawv. Cov tshuaj tau kho nyob rau hauv nrog lwm tus neeg sawv cev.
Unitiol raug tshuaj vim qhov tseeb tias ethyl cawv yog cov tshuaj lom muaj zog. Nrog nws cov khoom noj tsis tu ncua mus rau hauv lub cev, thiab txawm tias hauv cov khoom loj, kev txuam nrog cov co toxins tshwm sim, cov hlau hnyav tau tso. Qhov no yog lub nra hnyav rau nws.
Cov tshuaj no tau sau tseg rau cov neeg haus cawv haus cawv kom:
- Txhawm rau tiv thaiv thiab, yog tias tsim nyog, rov kho lub hauv nruab nrab cov hlab ntsha, uas feem ntau ntsib kev haus ib txwm muaj. Cov tshuaj ua rau muaj ntau pawg sulfide nyob rau theem kom raug. Nws muaj qhov cuam tshuam zoo ntawm cov neurons thiab lawv cov txheej txheem, vim nws txhawb lawv lub meej mom thiab tso cai rau lawv ua haujlwm zoo li qub.
- Tiv thaiv qhov pom ntawm cawv delirium. Cov neeg feem ntau uas haus dej haus cawv tsis tu ncua thiab nyob rau hauv ntau rau ib lub sij hawm ntev kev hnov lus thiab pom tau qhov sib txawv. Qhov no tshwm sim, raws li txoj cai, ntawm lub hauv paus tsis lees muab haus cawv. Nyob rau hauv lub sijhawm ntawm cov tsos ntawm delirium, ib tus neeg yog qhov txaus ntshai rau tib neeg thiab tuaj yeem tsim txom nws tus kheej.
Saib xyuas! Nws yog tsim nyog sau cia tias "Unithiol" tsis yog siv los daws cov tsos mob tshwm sim ntawm hangover lossis ua ib qho yeeb tshuaj rau luam yeeb cawv. Ntxiv mus, yog tias koj noj nws ib txhij nrog dej cawv, koj tuaj yeem ua rau qaug tshuaj lom.
Cov tshuaj yuav tsum tau saib xyuas los ntawm kws kho mob. Yog li, txhaj koob tshuaj thib ib raug pom zoo kom muab rau tus kws tshaj lij hauv tsev kho mob. Qhov no yuav ua rau nws muaj peev xwm taug qab lub cev qhov tshuaj tiv thaiv rau cov tshuaj, thiab yog tias muaj qhov tsis haum tshuaj tshwm sim, muab tus neeg mob nrog kev pab tsim nyog.
Thaum siv ceev xwmphem delirium 4-5 milliliters ntawm 5% kev daws yog muab ib zaug
Kev kho ntxiv tuaj yeem nqa tawm tom tsev. Hauv qhov no, nws yog ib qho tsim nyog yuav tsum tau soj ntsuam nruj ntawm cov tshuaj, uas tus kws kho mob tau sau tseg ib tus zuj zus rau txhua tus neeg mob.
Hauv kev haus dej cawv tsis tu ncua, tus neeg mob feem ntau yog 2-3 koob tshuaj rau lub lim tiam. Nyob rau hauv ib lub sijhawm, 3 mus rau 5 milliliters ntawm 5% daws yog txhaj. Hauv qhov xwm txheej no, "Unithiol" ua yeeb yam ntxiv hauv kev kho mob cawv quav.
Thaum siv ceev xwmphem delirium 4-5 milliliters ntawm 5% kev daws yog qhia ib zaug.
Qhov tshwm sim los ntawm kev noj tshuaj thiab phiv
Unitiol qhia tau hais tias muaj txiaj ntsig zoo hauv kev kho mob ntawm cawv cawv. Nws muaj peev xwm ntxuav lub cev ntawm co toxins, tiv thaiv nws cov tshuaj lom thiab tiv thaiv cov hlab hlwb ntawm kev rhuav tshem. Hauv qhov no, kev txheeb xyuas txog nws feem ntau zoo.
Tab sis nws tseem tshwm sim tias cov tshuaj zoo no ua rau tib neeg lub cev puas tsuaj. Raws li txoj cai, qhov no tshwm sim vim qhov tseeb tias ntau npaum li cas ntawm cov kev daws tau hais los ntawm tus kws kho mob tsis tau pom. Hauv qhov no, koj yuav ntsib tus mob tshaj plaws, uas yog tus cwj pwm los ntawm cov tsos mob hauv qab no:
- Teeb meem ua pa, txog siav. Nws ua rau neeg lub zog ua tsis taus pa thiab ua pa tawm. Nws xav tias lub cev tsis muaj pa, yog li nws siv sijhawm ntau dua pa, uas qee qhov tuaj yeem ncav cuag 20 zaug hauv 1 feeb.
- Vim tias qhov ua tsis taus pa tshwm sim, thiab ntshav ncig kuj cuam tshuam, daim tawv nqaij ua daj ntseg, thiab daim di ncauj thiab nqaj tawv tuaj yeem pib xiav.
- Lub plawv dhia ua ntau zaus, tachycardia tshwm sim. Qee qhov xwm txheej, cov mem tes maj mam qeeb.
- Cramps tshwm sim hauv nqua, feem ntau lawv tuaj yeem tuaj yeem yoo.
- Tus neeg raug tiv thaiv lub xeev thiab tuaj yeem poob mus rau hauv lub xeev tsis xeev (coma).
Qhov tshwm sim ntawm kev noj tshuaj ntau dhau yog qhov loj heev. Yog tias, tom qab txhaj koob tshuaj tau qhia, cov kev hloov saum toj no pib tshwm sim hauv lub cev, nws yog qhov yuav tsum tau qhia rau tus kws kho mob kom sai li sai tau - yog tias koj nyob hauv tsev kho mob. Nyob rau hauv rooj plaub thaum kev kho mob tawm hauv tsev, koj yuav tsum hu rau lub tsheb thauj neeg mob tam sim ntawd.
Ua rau kev tsis quav ntsej cov tsos mob ntawm kev haus ib qho dhau hwv lawm, kev tsis muaj lub sijhawm pab tau tuaj yeem ua rau tuag tau.
Kev phiv tshuaj kuj yog vim ib leeg tsis quav yeeb rau cov tshuaj. Hauv qhov no, cov tsos mob hauv qab no yuav tshwm sim:
- Cov tawv nqaij ua xua lossis Quincke's edema tshwm.
- Kev tsis xis nyob xeev siab, ntuav tshwm.
- Mob los yog kiv taub hau.
- Muaj tus tsis muaj zog.
- Daim tawv nqaij daj ntseg.
- Qhov zaus ntawm lub plawv dhia nce.
Yog tias cov tsos mob zoo li no tshwm sim, koj yuav tsum tsis kam noj tshuaj ntxiv. Raws li txoj cai, qhov no txaus los coj lub xeev ntawm lub cev.
Qhov tshwm sim ntawm kev noj tshuaj ntau dhau yog qhov loj heev
Cov tshuaj no ntau npaum li cas
"Unithiol" yog ib qho tshuaj pheej pheej yig, ntxiv rau, nws tsis nyuaj rau yuav nws. Ua qhov no tau pom zoo nyob hauv cov chaw muag tshuaj uas muag cov tshuaj muaj txiaj ntsig zoo uas muaj tag nrho cov ntaub ntawv xav tau.
Cov tshuaj tsis zoo thaum lub sijhawm zoo tshaj plaws yuav tsis muab ib qho txiaj ntsig ntawm kev txais tos. Nyob rau hauv qhov xwm txheej phem tshaj plaws, qhov cuav yuav ua rau muaj kev cuam tshuam tsis zoo rau lub cev ntawm cov neeg haus cawv, thiab tseem ua rau tuag taus.
Tus nqi ntawm cov tshuaj hauv khw muag tshuaj hauv Lavxias yog los ntawm 290 txog 500 rubles.
Unithiol yog txoj kev daws thoob ntiaj teb. Nws tsis tsuas yog pab ua rau kev kho mob hauv cawv quav tshuaj rau ntau cov khoom lag luam, tab sis kuj tseem raug samfwm rau lwm yam tshuaj lom. Cov tshuaj pab tshem ntawm lub cev:
- Arsenic
- Hnyav hlau ntsev.
- Mob glycosides.
Kev piav qhia, muaj pes tsawg leeg, tso tawm cov tshuaj ntawm cov tshuaj thiab nws ntim,
Ua li cas thiaj li nrhiav tau cov tshuaj "Unithiol" hauv cov tsev muag tshuaj? Cov lus qhia rau kev siv (cov tshuaj no tsis ua nyob rau hauv cov ntsiav tshuaj) qhia tau hais tias tus neeg sawv cev muaj nyob hauv hom tshuaj ntshiab, uas tau npaj rau subcutaneous lossis intramuscular thawj coj. Nws muaj qhov tsaus muag tsis hnov tsw ntawm hydrogen sulfide, ntxiv rau lub teeb xim liab (tej zaum yuav tsis muaj xim).
Cov khoom ntawm Unithiol npaj ua dab tsi? Cov lus qhia rau kev siv hais tias cov nquag ua hauj lwm ntawm tus neeg sawv cev no yog sodium dimercaptopropanesulfonate monohydrate. Tsis tas li ntawd, cov tshuaj muaj xws li cov koom haum pabcuam hauv cov qauv ntawm sulfuric acid, disodium edetate (Trilon B) thiab dej rau kev txhaj tshuaj.
Ntawm kev muag, cov tshuaj no tuaj hauv 5 ml iav ampoules. Lawv tau ntim rau hauv contour hlwb, uas tau muab tso rau hauv pob ntawv ntawm cov ntawv.
Cov chaw muag tshuaj
Unitiol tshuaj ua haujlwm li cas? Cov lus qhia rau kev siv paub tias nws yog tus neeg saib xyuas tshem tawm uas tshem tawm qhov sai ntawm sulfhydryl pawg. Hauv nws hom kev txiav txim, cov tshuaj no ze heev rau ntawm complexones.
Raws li cov kws tshaj lij, cov pawg sulfhydryl tuaj yeem hnov mob nrog thiol cov tshuaj lom hauv cov ntshav thiab cov ntaub so ntswg, thaum tsim cov khoom tawg tsis muaj teebmeem raug tshem tawm nrog zis.
Kev thaiv cov tshuaj lom pab ua kom rov ua haujlwm ntawm tag nrho cov kab mob enzyme hauv cov hlwb uas raug cuam tshuam los ntawm cov khoom lom. Cov tshuaj no yog siv los ua cov tshuaj tiv thaiv kev lom los ntawm arsenic, cov hlau hnyav thiab lawv cov khoom sib xyaw.
Hauv cov neeg muaj mob polyneuropathy ntawm mob ntshav qab zib keeb kwm thiab nrog amyloidosis ntxiv, cov tshuaj no tsis muaj zog mob, txhim kho kev ua haujlwm ntawm NS, thiab tseem tswj qhov permeability ntawm capillaries.
Kinetic nta
Lub zog ua tau zoo li cas yog muab xam nrog hauv cov tshuaj Unithiol? Cov lus qhia rau kev siv hais tias tom qab subcutaneous lossis txhaj tshuaj rau hauv lub cev, cov tshuaj lwg me me nkag mus rau hauv cov hlab ntshav. Qhov siab tshaj plaws ntawm cov tshuaj tau muab sau cia tom qab kwv yees li 40 feeb (tom qab i / m tswj hwm).
Ib nrab-lub neej ntawm cov tshuaj yog ob teev. Cov tshuaj tawm yog ua tiav nrog cov zis nyob rau hauv daim ntawv ntawm cov khoom ntawm tsis tiav oxidation.
Kev daws teeb meem
Ntawm cov cim qhia dab tsi tuaj yeem muab tshuaj rau tus neeg mob Unithiol noj tshuaj? Cov lus qhia rau kev siv (txhaj tshuaj yuav tsum tau nqa tawm tsuas yog tus kws paub txog kev kho mob) qhia tias qhov cuab yeej no siv rau:
- intoxication nrog bismuth, arsenic, chromium, muaj tshuaj lom lossis mob plawv glycosides,
- kev haus cawv ntev thiab tshee tshee tshee ua ib feem ntawm txoj kev kho mob ua ke,
- hepatocerebral dystrophy (Wilson-Konovalov syndrome).
Cov tshuaj "Unithiol": cov lus qhia rau kev siv
Hauv ampoules, qhov cuab yeej no tuaj yeem muas tau ntawm txhua lub tsev muag tshuaj. Raws li cov lus qhia, cov tshuaj no yuav tsum muab tshuaj subcutaneously lossis intramuscularly.
Hauv kev kho tshuaj ntawm arsenic intoxication, cov tshuaj yog siv ntawm tus nqi ntawm 50 mg ntawm cov nquag sib xyaw ib 10 kg ntawm tus neeg raug mob hnyav (uas yog 250-500 mg). Nyob rau thawj hnub ntawm kev kho mob, qhov koob tshuaj hais qhia yuav tsum tau siv ntau txog 4 zaug, rau zaum thib ob - txog 3 zaug, thiab ntxiv rau ib zaug.
Hauv kev kho mob ntawm kev lom nrog cov tshuaj lom mercury, cov tshuaj tau siv raws li cov txheej txheem saum toj no rau xya hnub lossis txog thaum cov tsos mob ntawm intoxication ploj tag.
Hauv kev kho mob ntawm cov mob glycoside lom rau thawj hnub thiab thib ob, cov tshuaj tau muab rau tus nqi ntawm 50 mg ntawm cov tshuaj tiv thaiv ib 10 kg ntawm tus neeg mob lub cev hnyav (i.e. 250-500 mg) plaub zaug hauv ib hnub, thiab hnub tom qab ob zaug lossis txog thaum cov tsos mob ntawm cardiotoxicity ploj.
Hauv kev kho mob ntawm hepatocerebral dystrophy, cov tshuaj tau muab tso rau hauv intramuscularly ntawm koob tshuaj 5-10 ml ntawm tus qauv concentration txhua txhua hnub lossis ob hnub tom qab. Lub sijhawm ntawm kev kho yog 26-30 hno. Yog tias yuav tsum tau ua, kev kawm raug rov ua dua tom qab 4 lub hlis.
Txog kev kho mob ntawm tus mob cawv cawv mus ntev, cov tshuaj tau siv hauv qhov tshaj li ntawm 4-5 ml hauv kev suav kom txog li 3 zaug hauv ib lub lis piam.
Hauv kev kho mob ntawm delirium, cov tshuaj yeeb tshuaj tau muab ib zaug (5 ml hauv kev suav txheem)
Kev siv ntau dhau thiab kev sib txuam yeeb tshuaj
Yog hais tias haus dej ntau dhau, tus neeg mob ua tsis taus pa, hyperkinesis, qaug zog, nkees thiab nkees. Hauv qhov no, kev kho cov tsos mob raug ua.
Cov tshuaj no yog pharmacologically tsis haum nrog cov neeg sawv cev uas suav cov hlau nyhav, nrog rau alkalis. Tsis tas li, nws tsis raug tsa nrog "Atsizol."
Cov neeg siv khoom tshuaj xyuas txog cov khoom siv hauv nqe lus nug yog qhov tsis tshua muaj siab. Qhov no yog vim muaj qhov tseeb tias cov tshuaj no siv tshwj xeeb hauv kev coj ua mus pw.
Raws li rau cov kws kho mob uas paub dhau los, lawv hais txog kev daws teebmeem ntawm Unitiol yog qhov ua tau zoo thiab muaj txiaj ntsig zoo uas tshem tawm cov co toxins, suav nrog thaum muaj cawv lom.
Cov Tshuaj Pharmacokinetics
Qhov siab tshaj plaws hauv cov ntshav ntshav tau mus txog 15-30 feeb tom qab txhaj tshuaj intramuscular. Cov tshuaj raug faib tsuas yog nyob rau theem aqueous (ntshav ntshav). Kev tshem tawm ib nrab-lub neej yog 1-2 teev. Muaj kev zam los ntawm lub raum, feem ntau yog nyob rau hauv daim ntawv ntawm cov khoom tsis ua tiav lossis ib feem ntawm oxidation, ib feem nyob rau hauv daim ntawv tsis hloov. Tsis cumulate.
Tsuas tshuaj thiab tswj hwm
Txog kev kho mob mob hnyav thiab mob ntev dhau los ntawm arsenic thiab mercury compound Unitiol muab tshuaj rau cov tshuaj intramuscularly lossis subcutaneously (5-10 ml ntawm kev daws ntawm 50 mg / ml). Txoj kev kho yuav tsum pib thaum ntxov tshaj plaws. Thaum muaj tshuaj lom nrog arsenic sib txuas, txhaj tshuaj yog tsim txhua 6-8 teev nyob rau thawj hnub, 2-3 hno txhua 8-12 teev nyob rau hnub thib ob, 1-2 txhaj rau hnub tom qab.
Ntawm mercury ntsev lom kev kho mob yog nqa tawm nyob rau hauv tib lub sij hawm tsawg kawg 6 hnub.
Ntawm mob caj dab glycoside lom hauv thawj 2 hnub, 5 lossis 10 ml ntawm ib qho kev daws teeb meem ntawm 50 mg / ml unitiol yog muab tshuaj intramuscularly lossis subcutaneously. Cov lus qhia yog nqa tawm 3-4 zaug hauv ib hnub, tom qab ntawd 1-2 zaug hauv ib hnub kom txog thaum cov txiaj ntsig cardiotoxic tsis ua haujlwm lawm.
Ntawm hepatocerebral kev tsis zoo tsa intramuscularly 5-10 ml ntawm ib qho kev daws ntawm 50 mg / ml txhua hnub lossis txhua txhua lwm hnub, chav kawm yog 25-30 txhaj tshuaj nrog kev so ntawm kev kawm ntawm 3-4 lub hlis.
Ntawm mob ntshav qab zib polyneuropathy Siv 5 ml ntawm ib qho kev daws ntawm 50 mg / ml rau 10 hnub.
Ntawm haus cawv ntev zuj zus txhaj tshuaj intramuscularly 3-5 ml ntawm kev daws ntawm 50 mg / ml 2-3 zaug ib lub lim tiam.
Kev tiv thaiv kev nyab xeeb
Kev qhia ntawm unitiol hauv kev mob lom tsis txwv tsis pub siv lwm yam kev ntsuas (kho lub plab, nqus tau pa, ua pa ntawm cov ntshav, cov ntshav qab zib).
Siv rau menyuam yaus. Tsis muaj cov ntaub ntawv qhia txog kev ua tau zoo thiab kev nyab xeeb ntawm kev siv tshuaj Unithiol hauv cov menyuam yaus.
Cuam tshuam rau lub peev xwm tsav tsheb thiab lwm yam uas muaj peev xwm txaus ntshai. Vim tias muaj kev pheej hmoo ntawm qhov tshwm sim tsis zoo thaum siv Unitiol (kiv taub hau, nce ntshav siab, tachycardia), thaum kho cov tshuaj, ib qho yuav tsum tsis kam tsav tsheb thiab tsis koom nrog kev ua si uas yuav tsum muaj kev mloog zoo.