Atoris ntsiav tshuaj analogues

Siv Atoris (lossis analogues), cov txiaj ntsig zoo heev tuaj yeem ua tiav hauv kev kho mob hyperlipidemia thiab kab mob plawv. Lwm qhov tshuaj tau siv tawm los tiv thaiv cov mob no hauv cov neeg laus dua 55 xyoos. Atoris siv tau zoo heev, yog li koj yuav tsum xav txog cov yam ntxwv ntawm nws siv, nrog rau qhov tshwj xeeb ntawm nws qhov hloov pheej yig. Cov no suav nrog cov tshuaj xws li Lipoford, Atomax, thiab Atorvastatin. Cov npe tshuaj analogues ntawm cov tshuaj thiab Atoris nws tus kheej muaj nyob rau hauv lawv cov muaj pes tsawg leeg ib yam muaj sia nyob ua ke - atorvastatin calcium.

Qhia me ntsis ntawm Atoris

Atoris cov tshuaj muaj nyob rau hauv pob uas muaj ntau npaum ntawm 10, 20, 30, 40, 60 lossis 80 mg. Qhov no yog ib qho tshuaj yeeb tshuaj statin uas ua ib txoj kev. Atorvastatin calcium pab txo cov haujlwm ntawm enzyme, uas yog lub hauv paus rau kev hloov pauv ntawm HMG-CoA rau mevalonic acid. Kev txhawb nqa ntawm qhov kev hloov pauv no khi qee qhov ntawm cov roj (cholesterol) phem, tshem tawm lawv los ntawm cov hlab ntsha. Qhov no thiaj li ua rau muaj qhov LDL cholesterol nyob hauv cov ntshav siab.

Atoris ntsiav tshuaj muaj cov nyhuv los tiv thaiv atherosclerotic, uas ua tau nws tus kheej los ntawm kev ua ntawm cov tshuaj tseem ceeb ntawm cov hlab ntsha thiab cov ntshav sib xyaw.

Cov txiaj ntsig zoo ntawm atorvastatin nyob rau saum npoo ntawm cov hlab ntsha yog ua kom paub tseeb los ntawm kev cuam tshuam ntawm cov synthes ntawm isoprenoids, uas txo txoj kev pheej hmoo ntawm kev loj hlob ntawm lawv cov qog puab, uas txhais tau tias txo qis hauv lawv qhov khoob.

Ntawm cov lus qhia dav dav rau kev noj tshuaj, cov hauv qab no tuaj yeem sib txawv:

1. Kev tswj nruj rau kev noj haus (ua ntej thiab thaum kho) yuav pab txo ntshav lipids.
2. Cov tshuaj yuav tsum noj nyob rau tib lub sijhawm 1 zaug hauv ib hnub.
3. Nws yog ib qho tsim nyog yuav tsum tau soj ntsuam tas li ntawm lub siab ua haujlwm.
4. Nrog kev txhim kho cov leeg mob lossis ua kom tsis muaj zog ntawm qhov tsis paub, nrog nrog mob ua npaws, nws raug nquahu kom tsis txhob noj tshuaj Atoris thiab sab laj nrog kws kho mob.
5. Atoris yog contraindicated rau cov menyuam yaus, thiab poj niam lub sijhawm thaum lactation thiab cev xeeb tub.
6. Ntawm cov contraindications yog mob siab tsis ua haujlwm, mob ntsws, mob pob txha mob pob txha.
7. Yog tias muaj kev fab tshuaj rau ib qho ntawm cov tshuaj, nws cov thawj coj kuj tseem tsis tau pom zoo.
8. Nrog kev ceev faj yuav tsum tau coj mus rau cov neeg mob kev txom nyem los ntawm kev haus cawv.

Tom qab 2 lub lim piam ntawm kev kho mob, ntshav hauv cov ntshav qis yuav poob. Qhov no yuav tshwm sim hauv kev tshuaj ntsuam xyuas. Qhov siab tshaj plaws yuav hnov ​​qab tom qab 25-30 hnub. Qhov kev kho kom zoo dua qub los ntawm kev kho mob yuav tsuas kav ntev dua tsuas yog thaum ua tiav tag nrho cov chav kawm tau teev tseg los ntawm kws kho mob. Hauv qhov no, ntau npaum li cas yuav raug txiav txim los ntawm theem pib ntawm LDL cov roj (cholesterol) hauv cov ntshav thiab qhov mob hnyav.

Cov yam ntxwv ntawm kev siv cov tshuaj-analog Lipoford

Lipoford yog ntawm Indian keeb kwm thiab yog qhov pheej yig dua ntawm Atoris. Cov tshuaj muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj nrog kev saib xyuas ntawm cov nquag muaj ntawm 10 lossis 20 mg. Lipoford yog pawg ntawm lipid-txo cov tshuaj uas tau siv rau kev tiv thaiv thiab kho cov kab mob plawv los ntawm cov roj hauv siab.

Qhov tshwj xeeb ntawm kev nqis tes ntawm Lipoford thiab Atoris yuav luag zoo ib yam, txij li ob qho tib si suav nrog atorvastatin calcium ua lub ntsiab lus tseem ceeb tshuaj sib xyaw. Tab sis txhawm rau hloov Atoris nrog cov pheej yig dua, nws yog qhov yuav tsum tau sab laj nrog tus kws kho mob uas tau kho tus mob.

Qhov taw qhia rau kev siv Lipoford yuav yog ib qho ntawm cov xwm txheej:

• muaj zog ntxiv ntawm cov roj (cholesterol) tag nrho,
• cov roj (cholesterol) LDL ntau ntxiv
• ntshav siab ntawm apolipoprotein B thiab triglycerides,
• thawj, roj ntsha heterozygous tsev neeg thiab tsis-tsev neeg hypercholesterolemia (yog tias LDL cov ntshav siab dhau heev),
• homozygous tsev neeg hypercholesterolemia,
• sib xyaw hyperlipidemia,
• siab ntshiab ntshiab triglyceride ntau,
• dysbetalipoproteinemia,
• pathology ntawm cov hlab plawv system,
• kev pheej hmoo ntawm kev tsim mob plawv: hnub nyoog laus, kev quav yeeb dawb, ntshav qab zib, thiab lwm yam.

Thaum siv Lipoford, koj yuav tsum ua raws li kev noj zaub mov tshwj xeeb. Kev noj zaub mov zoo yuav tsum yog los ntawm cov tais diav muaj roj tsawg thiab khoom noj.

Atomax yog lwm qhov tshwj xeeb Atoris

Atomax yog lwm qhov chaw ntawm Indian Atoris hloov nrog cov nqi pheej yig dua. Daim foos tso tawm yog tib yam. Cov tshuaj ntsiav muaj nyob rau hauv tsuas yog ob qhov tshuaj: 10 thiab 20 mg. Lub ntsiab ntawm cov Atomax yog atorvastatin calcium trihydrate. Cov lus sib xyaw ua ke muaj txog 10 yam khoom ntxiv, suav nrog lactose, crospovidone, hmoov txhuv nplej siab, thiab lwm yam.

Atomax yog noj ntawm qhov ncauj, tsis hais leej twg noj mov. Cov tshuaj yog zoo nqus, thiab tom qab 1-2 teev cov ntsiab lus siab tshaj plaws ntawm cov tshuaj nquag tau pom nyob hauv cov ntshav.

Cov tshuaj tiv thaiv thaum noj Atomax tuaj yeem yog:

• kev fab tshuaj rau cov khoom hauv cov khoom muaj pes tsawg leeg,
• cev xeeb tub nyob rau txhua lub sijhawm
• pub niam mis
• exacerbation ntawm daim siab mob siab,
• muaj ntshiab transaminase kev ua si,
• cov me nyuam muaj hnub nyoog
• quav cawv
• tej kab mob siab (siv cov khoom nrog ceev faj thiab ib txwm nyob hauv kev saib xyuas ntawm tus kws kho mob),
• ntxhov siab electrolyte tshuav nyiaj li cas,
• kev cuam tshuam nyob rau hauv endocrine system,
• exacerbation ntawm cov txheej txheem sib kis (piv txwv, sepsis),
• phais cov haujlwm, thiab lwm yam.

Qhov tseem ceeb uas tus neeg mob yuav tsum nco ntsoov: Atomax nrog cov roj (cholesterol) tuaj yeem siv, tab sis tsuas yog raws li kws kho mob sau tseg. Qhov no yog vim qhov tseeb tias nrog cov khoom noj tsis zoo, qhov ntxim nyiam ntawm ntau yam kev mob tshwm sim ntau ntxiv ntau zaus.

Hloov chaw hauv Atorvastatin

Ntawm cov tshuaj hauv tsev uas tuaj yeem hloov Atoris, cov tshuaj tau raug faib uas muaj lub npe zoo nrog cov tshuaj nquag - Atorvastatin. Nws raug nqi tsawg dua li txhua Atoris analogues, raws li nws yog tsim hauv Lavxias Lavxias thiab tsis sia mus thoob ntiajteb. Tab sis hais txog qhov ua tau zoo, cov tshuaj yeeb tshuaj tsis muaj kabmob ntau dua. Cov ntsiav tshuaj yog tsim nrog ntau qhov sib txawv ntawm cov tshuaj nquag: 10-40 mg.

Cov kab ke no tuaj yeem kho rau tib qho kev ntsuas raws li cov tshuaj saum toj no, txij li lawv cov tshuaj tiv thaiv yuav luag zoo ib yam. Ntawm cov ntsiab lus contraindications yog cev xeeb tub, pub niam mis, mob siab nyob rau theem mob huam tuaj, thiab ib leeg tsis quav ntsej.

Ntawm cov kev mob tshwm sim tuaj yeem tshwm sim:

• kev ntxhov siab vim pw tsaug zog
• mob taub hau
• ua txhaum ntawm cov quav (raws plab, cem quav),
• xeev siab
• kev siv roj ntxiv hauv cov hnyuv,
• dav malaise
• rov qab mob
• cramps
• daim tawv nqaij ua pob, thiab lwm yam.

Yog tias cov roj (cholesterol) nce siab, cov cuab yeej yuav pab daws qhov teeb meem, tab sis raug rau cov tshuaj zoo. Yog li, nws yog ib qho tseem ceeb heev uas yuav tsum ua raws li kev kho mob muab tso ua ke los ntawm kws kho mob. Nyob rau hauv rooj plaub ntawm overdose, cov tshuaj yog tso tseg. Tom qab kev nqus tuaj yeem tiv thaiv tau los ntawm kev ntxuav lub plab, noj tshuaj laxative lossis qee qhov nqus. Tsis tas li ntawd, tus kws kho mob tuaj yeem sau ntawv kho cov tsos mob, uas yuav ua kom saib xyuas thiab tuav cov haujlwm tseem ceeb.

Pheej Yig Atoris Hloov

Cov analogue yog pheej yig dua los ntawm 250 rubles.

Qhov hloov pauv no yog tsim nyob rau hauv Russia, yog li nws raug nqi tsawg dua li "cov tshuaj qub". Nws muaj tib cov npe ntawm cov ntsuas rau kev teem caij. Contraindicated nyob rau hauv rooj plaub ntawm hypersensitivity rau yeeb tshuaj, mob siab, thaum cev xeeb tub thiab lactation.

Cov analogue yog pheej yig dua los ntawm 211 rubles.

Cov tsim tawm: Oxford (Is Nrias teb)
Cov Ntawv Tso Tawm:

• 20 mg ntsiav tshuaj, 30 pcs.

Lwm cov tshuaj raws li atorvastatin calcium hauv cov qauv tshuaj. Cov muaj pes tsawg leeg ntawm Lipoford tsis txawv ntau ntawm Atoris, yog li cov ntsuas, contraindications thiab phiv yuav luag zoo ib yam.

Atomax (ntsiav tshuaj) → hloov Chaw: 127 Sab saum toj

Cov analogue yog pheej yig dua los ntawm 179 rubles.

Chaw tsim tshuaj paus: Hetero Drags Limited (Is Nrias teb)
Cov Ntawv Tso Tawm:

• 20 mg ntsiav tshuaj, 30 pcs.

Atomax yog Indian hloov chaw rau Atoris muaj tib hom kev tso tawm. Kuj tseem siv rau cov tshuaj lipid-txo qis thiab siv tib lub DV. Contraindicated thaum cev xeeb tub thiab lactation. Kev phiv yog qhov ua tau, ua ntej kev sib tham nrog kws kho mob yog qhov tsim nyog.

Analogs hauv kev muaj pes tsawg leeg thiab qhia txog kev siv

Cov npe saum toj no ntawm cov yeeb tshuaj analogues, uas qhia Atoris hloov chaw, yog qhov tsim nyog tshaj plaws vim tias lawv muaj tib cov tshuaj sib luag thiab sib luag ua ke raws li kev taw qhia rau kev siv

Analogs los ntawm qhov taw qhia thiab cov qauv ntawm kev siv

Sib txawv muaj pes tsawg leeg, tuaj yeem ua ke nyob rau hauv kev taw qhia thiab cov qauv ntawm daim ntawv thov

Yuav ua li cas thiaj nrhiav tau qhov pheej yig tshuaj ntawm cov tshuaj kim?

Txhawm rau kom pom qhov pheej yig cov khoom sib piv rau cov tshuaj, cov dav dav lossis cov lus sau, ua ntej txhua yam peb pom zoo kom them sai sai rau qhov muaj pes tsawg leeg, uas yog rau tib cov tshuaj nquag thiab qhia tau rau kev siv. Cov tshuaj sib xyaw zoo ib yam ntawm cov tshuaj yuav qhia tau tias cov tshuaj cuam tshuam nrog cov tshuaj, kws tshuaj sib npaug lossis chaw muag tshuaj. Txawm li cas los xij, tsis txhob hnov ​​qab txog qhov ua tsis muaj zog ntawm cov tshuaj uas zoo sib xws, uas tuaj yeem cuam tshuam kev nyab xeeb thiab ua haujlwm. Tsis txhob hnov ​​qab txog cov lus qhia ntawm cov kws kho mob, kev noj tshuaj rau nws tus kheej tuaj yeem tsim kev puas tsuaj rau koj kev noj qab haus huv, yog li nco ntsoov sab laj nrog koj tus kws kho mob ua ntej siv cov tshuaj.

Pharmacological kev txiav txim

Atorvastatin yog tus neeg saib xyuas hypolipidemic los ntawm pab pawg ntawm statins. Lub tshuab tseem ceeb ntawm kev ua ntawm atorvastatin yog qhov inhibition ntawm kev ua si ntawm HMG-CoA reductase, ib qho enzyme uas catalyzes hloov dua siab tshiab ntawm HMG-CoA rau mevalonic acid. Qhov kev hloov pauv no yog ib qho ntawm thawj kauj ruam ntawm kev sib luag (cov roj (cholesterol)) cov khoom sib txuas hauv lub cev. Atorvastatin kev tiv thaiv ntawm cov roj (synthesis) ua rau cov tshuaj tiv thaiv kab mob LDL ntau zog hauv lub siab, ntxiv rau cov ntaub so ntswg. Cov receptors khi LDL cov roj ntsha thiab tshem tawm cov ntshav ntshav, uas ua rau kom txo qis hauv cov concentration ntawm LDL-C hauv cov ntshav.

Cov nyhuv antiatherosclerotic ntawm atorvastatin yog qhov tsim nyog ntawm nws cov nyhuv rau ntawm phab ntsa ntawm cov hlab ntsha thiab cov ntshav ua haujlwm. Atorvastatin inhibits kev sib txuas ntawm isoprenoids, uas yog kev loj hlob ntawm cov hlwb ntawm cov roj ntsha sab hauv. Raws li kev cuam tshuam ntawm atorvastatin, endothelium-dependability ntawm cov hlab ntshav txhim kho, qhov kev sib txuam ntawm cov cholesterol-LDL, apolipoprotein B, triglycerides (TG) poob qis, cov concentration ntawm cov roj-HDL thiab apolipoprotein A nce ntxiv.

Atorvastatin txo qis viscosity ntawm ntshav ntshav thiab cov kev ua ntawm qee yam coagulation yam thiab platelet aggregation. Vim qhov no, nws txhim kho hemodynamics thiab normalizes qhov mob ntawm coagulation system. HMG-CoA reductase inhibitors tseem cuam tshuam cov metabolism hauv macrophages, thaiv lawv cov kev ua kom zoo thiab tiv thaiv kev tawg ntawm atherosclerotic plaques.

Raws li txoj cai, txoj kev kho mob ntawm atorvastatin kev txhim kho tom qab 2 lub lis piam ntawm kev siv Atoris®, thiab cov txiaj ntsig siab tshaj plaws tau tiav tom qab 4 lub lis piam.

Tseem ceeb txo txoj kev pheej hmoo ntawm kev tsim ischemic muaj teeb meem (suav nrog kev tuag los ntawm myocardial infarction) los ntawm 16%, kev pheej hmoo ntawm rov qab pw tsev kho mob rau angina pectoris, nrog cov cim ntawm myocardial ischemia, los ntawm 26%.

• Txo cov ntsiab lus ntawm cov roj (cholesterol) tag nrho, cov roj cholesterol-LDL, apolipoprotein B thiab triglycerides nyob rau hauv cov ntshav cov ntshav ntawm cov neeg mob uas muaj thawj hyperlipidemia (Fredrickson yam IIa thiab IIb), suav nrog polygenic hypercholesterolemia, tsev neeg heterozygous hypercholesterolemia thiab sib xyaw hyperlipidemia.
• Txo cov kev xav ntau ntxiv ntawm cov roj (cholesterol) tag nrho, cov roj cholesterol-LDL thiab apolipoprotein B hauv cov neeg mob homozygous tsev neeg hypercholesterolemia.
• Atoris® tsub kom lub siab ntawm HDL-C hauv ntshav dej thiab txo qhov feem ntawm LDL-C / HDL-C.
• Nws yog siv nyob rau hauv cov ntaub ntawv ntawm tsis txaus ntseeg ntawm kev noj zaub mov noj thiab lwm yam tsis-pharmacological txoj kev kho mob.

Kev Tiv Thaiv Kab Mob:

• Kev tiv thaiv kab mob plawv hauv cov neeg mob tsis muaj kev soj ntsuam kab mob ntsig txog lub plawv, tab sis nrog ntau yam kev pheej hmoo rau nws txoj kev loj hlob: hnub nyoog laus dua 55 xyoos, kev quav yeeb dawb, mob ntshav siab, ntshav qab zib mellitus, ntshav muaj roj ntshav tsawg HDL roj ntshav, ntshav sib chwv, suav nrog tawm tsam keeb kwm ntawm dyslipidemia.
• Kev tiv thaiv kab mob thib ob hauv kev mob plawv hauv cov neeg mob plawv mob plawv txhawm rau txhawm rau txo qis kev phom sij tag nrho, mob ntshav hlab plawv, mob hlab ntsha tawg, rov qab pw tsev kho mob rau angina pectoris thiab qhov xav rov kho dua.

Cov Yuav Tsum Muaj

• Hypersensitivity rau ib yam ntawm cov tshuaj.
• Kev muaj mob rau daim siab (nrog rau mob siab ua mob ntev, mob siab hom mob voos).
• Daim siab ua haujlwm.
• Cov mob cirrhosis ntawm lub siab ntawm ib qho kev etiology.
• Ib qho kev nce ntawm cov kev ua ntawm hepatic transaminases ntawm cov tsis paub keeb kwm los ntawm ntau dua 3 zaug piv nrog VGN.
• Skeletal leeg mob.
• Lactase deficiency, lactose intolerance, qabzib-galactose malabsorption syndrome.
• Cev xeeb tub thiab lub sijhawm pub mis niam.
• Lub hnub nyoog txog 18 xyoo (qhov ua tau zoo thiab kev nyab xeeb ntawm kev siv tsis tsim).

Nrog kev ceev faj: kev haus cawv, keeb kwm ntawm kab mob siab.

Cev xeeb tub thiab lactation

Atoris® yog sib kis thaum cev xeeb tub thiab thaum pub niam mis. Kev tshawb fawb tsiaj qhia tias kev pheej hmoo rau tus me nyuam hauv plab yuav dhau qhov txiaj ntsig tau rau leej niam.

Hauv cov poj niam ntawm lub hnub nyoog yug me nyuam uas tsis siv txoj hauv kev txhim kho kom muaj txiaj ntsig, kev siv Atoris® tsis pom zoo. Thaum npaj kev cev xeeb tub, koj yuav tsum tsum tsis siv Atoris® yam tsawg 1 hlis ua ntej koj npaj cev xeeb tub.

Tsis muaj pov thawj ntawm kev faib cov atorvastatin nrog rau niam mis. Txawm li cas los xij, hauv qee hom tsiaj, qhov kev nkag siab ntawm atorvastatin hauv cov ntshav thiab cov kua mis yog qhov zoo sib xws. Yog tias yuav tsum tau siv cov tshuaj Atoris® lub sijhawm lactation, txhawm rau kom tsis txhob muaj kev phom sij ntawm cov menyuam mos, kev pub niam mis yuav tsum tau tsum.

Cov lus qhia tshwj xeeb

Ua ntej pib txoj kev kho mob nrog Atoris®, tus neeg mob yuav tsum yog tus kws kho mob hypocholesterolemic noj cov zaub mov, uas nws yuav tsum ua raws lub sijhawm kho tag nrho.

Kev nce ntxiv ntawm kev ua si ntawm hepatic enzymes hauv ntshav cov ntshav tuaj yeem pom thaum lub sijhawm kho Atoris®. Qhov nce no feem ntau me me thiab tsis muaj qhov tseem ceeb hauv lub chaw kuaj mob. Txawm li cas los xij, nws raug nquahu kom soj ntsuam kev ua haujlwm ntawm daim siab enzymes hauv cov ntshav cov ntshav ua ntej kev kho mob, tom qab 6 thiab 12 lub lis piam thiab nrog kev nce ntxiv ntawm koob tshuaj atorvastatin. Yog tias muaj qhov peb-zaug ntxiv hauv kev ua ntawm ACT thiab / lossis ALT tus txheeb ze rau HBV, kev kho nrog Atoris® yuav tsum tsis ua ntxiv.

Atorvastatin tuaj yeem ua rau nce ntawm kev ua ntawm CPK thiab aminotransferases.

Hauv cov poj niam ntawm lub hnub nyoog yug me nyuam uas tsis siv kev tswj kom tsis pub muaj txiaj ntsig, kev siv Atoris® tsis pom zoo. Yog tias tus neeg mob npaj lub cev xeeb tub, nws yuav tsum tsum tsis txhob noj Atoris® tsawg kawg ib hlis ua ntej lub sijhawm npaj xeeb menyuam.

Cov neeg mob yuav tsum tau ceeb toom tias lawv yuav tsum sab laj nrog kws kho mob sai sai yog tias tsis hnov ​​qhov mob lossis cov leeg tsis muaj zog. Tshwj xeeb yog hais tias lawv nrog tus mob malaise lossis kub taub hau.

Kev kho mob nrog Atoris® tuaj yeem ua rau myopathy, uas qee zaum nrog rhabdomyolysis, ua rau lub raum tsis ua haujlwm. Txoj kev pheej hmoo ntawm cov kev mob hnyav no nce ntxiv thaum noj ib lossis ntau dua ntawm cov tshuaj hauv qab no nrog Atoris®: fibroic acid derivatives, niacin, cyclosporine, nefazodone, qee cov tshuaj tua kab mob, azole antifungals, thiab HIV tiv thaiv kab mob tiv thaiv.

Hauv kev soj ntsuam cov tsos mob ntawm tus mob myopathy, nws tau pom zoo tias ntshav ntau ntawm CPK raug txiav txim siab. Nrog kev nce siab 10 npaug ntawm VHF kev ua haujlwm ntawm KFK, kev kho mob nrog Atoris® yuav tsum tsis ua mus ntxiv.

Muaj cov ntawv tshaj tawm txog kev txhim kho ntawm atonic fasciitis nrog kev siv atorvastatin, txawm li cas los xij, kev sib txuas nrog kev siv cov tshuaj yog ua tau, tab sis tseem tsis tau muaj pov thawj, tus etiology tseem tsis tau paub.

Cov neeg mob yuav tsum tau ceeb toom tias lawv yuav tsum tau sab laj nrog kws kho mob tam sim ntawd yog tias tsis hnov ​​qhov mob lossis cov leeg tsis muaj zog, tshwj xeeb yog tias lawv nrog mob lossis kub taub hau.

Atoris® muaj lactose, thiab yog li ntawd nws siv los ntawm cov neeg mob uas tsis muaj lactase, lactose intolerance thiab glucose-galactose malabsorption syndrome yog contraindicated.

Cuam Tshuam rau kev muaj peev xwm tsav tsheb thiab ua haujlwm nrog tshuab.

Muab cov tseem muaj kiv taub hau, ceev faj yuav tsum tau siv thaum tsav tsheb thiab lwm cov cuab yeej ua haujlwm uas yuav tsum muaj kev mloog zoo thiab ceev ntawm lub cev kev xav.

1 ntsiav tshuaj muaj:

Yam tshuaj muaj sia: atorvastatin calcium 10.36 mg, (sib npaug ntawm 10 mg atorvastatin, feem).

Cov muaj tswv yim: povidone - 5.8 mg, sodium lauryl sulfate - 2.9 mg, calcium carbonate - 31.84 mg, MCC - 29 mg, lactose monohydrate - 57.125 mg, croscarmellose sodium - 7.25 mg, magnesium stearate - 0.725 mg.

Plhaub zaj duab xis: Opadry II HP 85F28751 dawb (polyvinyl cawv, titanium dioxide (E171), macrogol 3000, talc) - 4.35 mg.

Tsuas tshuaj thiab tswj hwm

Sab hauv, tsis hais txog pluas noj.

Ua ntej pib siv cov tshuaj Atoris®, tus neeg mob yuav tsum pauv mus rau qhov kev noj haus uas ua kom muaj qhov txo qis ntawm cov lipids hauv cov ntshav, uas yuav tsum tau pom thaum lub sijhawm kho tag nrho nrog cov tshuaj. Ua ntej pib txoj kev kho mob, koj yuav tsum tau sim ua kom tiav kev tswj hwm ntawm hypercholesterolemia los ntawm kev tawm dag zog thiab kev poob phaus hauv cov neeg mob rog, nrog rau kev kho mob rau lwm tus kab mob.

Kev kho mob pib nrog kev pom zoo kom pib ntawm 10 mg. Cov koob tshuaj ntawm cov tshuaj txawv ntawm 10 txog 80 mg ib hnub ib zaug thiab raug xaiv los xav txog thawj zaug kev xav ntawm LDL-C, lub hom phiaj ntawm txoj kev kho thiab cov tib neeg siv tshuaj kho kom zoo.

Atoris® tuaj yeem nqa ib zaug thaum lub sijhawm txhua hnub, tab sis tib lub sijhawm txhua hnub. Kev kho mob nyhuv yog pom tom qab 2 lub lis piam ntawm kev kho mob, thiab cov txiaj ntsig siab tshaj plaws yuav tshwm sim tom qab 4 lub lis piam. Yog li, cov koob tshuaj yuav tsum tsis txhob hloov ua ntej 4 lub lis piam tom qab pib siv tshuaj nyob hauv koob tshuaj dhau los.

Thaum pib kho thiab / lossis thaum qhov nce ntxiv, nws yog qhov yuav tsum tau saib xyuas qhov kev nkag siab ntawm cov lipids hauv cov ntshav ntshav txhua 2-4 lub lis piam thiab kho qhov tshuaj raws li.

Thawj (kab mob heterozygous muaj keeb thiab polygenic) hypercholesterolemia (hom IIa) thiab sib xyaw hyperlipidemia (hom IIb): kev kho mob pib nrog kev pom zoo kom pib koob tshuaj, uas tau nce ntxiv tom qab 4 lub lis piam, nyob ntawm tus neeg mob teb. Qhov nyiaj pab ntau tshaj txhua hnub yog 80 mg.

Homozygous muaj keeb tiv thaiv hypercholesterolemia: cov koob tshuaj ntau yog tib yam li nrog lwm hom hyperlipidemia. Thawj koob tshuaj tau xaiv ib tus zuj zus, nyob ntawm qhov mob hnyav ntawm tus kab mob. Hauv feem ntau cov neeg mob homozygous kab mob hypercholesterolemia, cov txiaj ntsig zoo tshaj plaws yog pom nrog kev siv tshuaj hauv ib hnub ntawm 80 mg (ib zaug). Atoris® yog siv los ua kev kho rau lwm txoj hau kev kho mob (plasmapheresis) los yog kev kho mob tseem ceeb yog tias kev kho nrog lwm txoj kev tsis tuaj yeem ua.

Cov pab pawg neeg tshwj xeeb.

Cov neeg laus cov neeg mob.

Hauv cov neeg mob laus, cov koob tshuaj ntawm Atoris® yuav tsum tsis txhob hloov pauv.

Lub raum khiav tsis zoo.

Nws tsis cuam tshuam rau qhov kev txiav txim ntawm atorvastatin hauv ntshav ntshav los yog cov neeg kawm poob qis hauv kev saib xyuas ntawm LDL-C nrog kev siv atorvastatin, yog li, hloov cov tshuaj ntawm cov tshuaj tsis tas yuav tsum tau ua.

Lub siab ua haujlwm tsis zoo.

Hauv cov neeg mob uas muaj lub siab ua haujlwm tsis zoo, kev ceev faj yog qhov tsim nyog (vim kev ua haujlwm qeeb hauv kev tshem tawm cov tshuaj tawm hauv lub cev). Thaum muaj qhov xwm txheej zoo li no, cov chaw kuaj mob thiab kuaj ntsuas yuav tsum tau ua tib zoo saib (kev soj ntsuam ACT thiab ALT kev ua haujlwm). Nrog txoj kev nce siab ntawm hepatic transaminases, koob tshuaj Atoris® yuav tsum tau txo lossis txoj kev kho yuav tsum tau txiav tawm.

Siv nrog rau lwm cov tshuaj.

Yog tias tsim nyog, kev siv tib lub sijhawm ntawm cyclosporine koob tshuaj Atoris® yuav tsum tsis pub tshaj 10 mg.

Atoris - cov ncauj lus dav dav

Tus neeg sawv cev hypolipidemic Atoris (Atoris) yog ib feem ntawm pab pawg ntawm statins uas thaiv qhov ua haujlwm ntawm enzyme hauv lub siab (HGM-CoA), uas yog lub luag haujlwm tsim cov roj (cholesterol).

Cov tshuaj yog tsim hauv cov ntsiav tshuaj hauv cov tshuaj sib txawv: 10 mg, 20 mg thiab 40 mg ntawm cov tshuaj tiv thaiv nquag ntawm atorvastatin. Ib ntsiav tshuaj muaj ib qho me me ntawm excipients - povidone, sodium lauryl sulfate, magnesium stearate, lactose monohydrate, thiab lwm yam.

Lub tshuab ntawm kev ua ntawm cov tshuaj cuam tshuam nrog kev tsub tawm ntawm cov roj hluav taws xob ua kom zoo dua qub thiab muaj zog ntawm cov LDL receptors hauv cov nqaij mos thiab lub siab. Tom ntej no, cov khi khi khi cov ntshav LDL, tshem lawv ntawm cov hlab ntshav. Yog li, muaj kev ua kom ntshav cov ntshav tsawg.

Tus kws kho mob tau sau ntawv Atoris rau cov xwm txheej zoo li no:

• cov neeg mob uas tsis tas kho mob rau lub plawv mob txhawm rau txhawm rau txo qis kev phom sij myocardial infarction, mob stroke, angina pectoris thiab xav tau tus mob myocardial revascularization sai,
• cov neeg mob uas muaj mob ntshav qab zib tsis yog-insulin-mob ntshav qab zib mellitus (yam 2) tsis muaj cov kws kho mob ntsig txog lub plawv mob txhawm rau txo qis kev pheej hmoo ntawm lub plawv thiab mob hlab ntsha tawg,
• cov neeg mob uas tau hais tawm lub plawv mob txhawm rau txhawm rau txo qis kev pheej hmoo tsis mob ntshav qab zib, mob ntshav khov thiab tsis tuag, mob ntshav tawm hauv lub plawv, txoj kev xav rau myocardial revascularization thiab pw hauv tsev kho mob vim lub plawv tsis ua haujlwm,
• raws li kev ntxiv rau cov khoom noj tshwj xeeb rau thawj (tsev neeg / tsis yog tsev neeg) thiab sib xyaw (hom IIa thiab IIb) hypercholesterolemia,
• raws li kev noj haus ntxiv rau kev noj haus rau hypertriglyceridemia (hom IV), thawj dysbetalipoproteinemia (hom III), nrog rau homozygous tsev neeg hypercholesterolemia,
• cov neeg mob hnub nyoog 10-17 xyoo uas muaj keeb kwm tsev neeg muaj mob plawv thaum ntxov los yog ntau tshaj ob yam ntawm lawv txoj kev loj hlob.

Atoris muaj tsawg tsawg ntawm cov contraindications. Ntawm lawv, nws yog qhov yuav tsum tau hais txog qhov tsis haum lub ntsej muag rau lub Cheebtsam ntawm cov ntsiav tshuaj, cev xeeb tub thiab lub sijhawm lactation, daim siab ua haujlwm siab thiab nce qib ntawm qhov hloov pauv hloov.

Pheej yig analogues thiab hloov chaw ntawm cov tshuaj atoris rau cov menyuam yaus thiab cov laus

Atoris yog tshuaj ntawm lub hauv paus chiv keeb. Cov tshuaj Analogues pheej yig dua Atoris muaj cov khoom zoo tib yam los yog sib xws, tsim nyob rau txawv teb chaws, suav nrog cov tuam ntxhab. Cov tshuaj nws tus kheej nyob rau hauv Russia raug nqi txog 400 - 1000 rubles. Qhov kev hloov pauv ntawm tus nqi no vim yog qhov sib txawv ntawm cov naj npawb ntawm cov ntsiav tshuaj hauv pob thiab hauv lawv qhov ntau npaum li cas ntawm cov tshuaj yeeb dej caw.

Cov lus qhia rau kev siv qhia tsis tau txaus rau cov neeg yuav khoom feem ntau lo lus hyperlipidemia. Qhov tseeb, qhov no txhais tau tias kev nce qib hauv lipids hauv cov ntshav (ua piv txwv, cov roj (cholesterol) tuaj yeem hu ua, tab sis muaj ntau yam khoom siv), cov no yog ntau yam muaj kev ywj pheej ntawm cov tshuaj uas insoluble hauv cov ntshav thiab tuaj yeem ua rau vascular blockage.

Lawv muaj qhov cuam tshuam kev ua txhaum ntawm cov rog metabolism. Cov tshuaj ntawm hom no tuaj yeem tshem cov lipids los ntawm cov ntshav thiab txo lawv qib.

Kev nce ntxiv ntawm cov tshuaj nquag yog tsim nyog rau cov neeg mob uas muaj ntau theem ntawm tus kab mob.

Analogs ntawm Lavxias teb sab ntau lawm

Pheej yig analogues ntawm cov tshuaj ntawm cov chaw tsim tshuaj paus muaj peev xwm tiv nrog kev nce ntxiv ntawm cov qib ntawm lipid formations. Thiab tsis tas li cov tshuaj pheej pheej yig dua nws txawv hauv cov yam ntxwv zoo. Hauv cov lus hauv qab no peb sau cov feem ntau.

Ukrainian hloov pauv

Cov npe ntawm Ukrainian-ua analogues muaj ntuj npaj. Hloov nrog cov tshuaj pheej yig yog pom zoo nyob rau hauv thawj theem ntawm tus kabmob lossis ua cov khoom siv ntxiv.

1. Alfalfa kua rojCov. Cov tshuaj, tsim nyob rau hauv lub hauv paus ntawm lub ntuj sib xyaw, yog tsim nyog rau cov hluas thiab cov laus. Txais los ntawm kev kawm. Nws raug nqi 210 rubles.
2. AterovitCov. Pab ua kom cov hlab ntshav muaj zog thiab txo cov roj cholesterol. Cov tshuaj muaj pes tsawg leeg yog tshuaj noj. Lawv raug nqi 140 rubles.
3. CardiochistinCov. Nws yog tsim rau cov ntshav siab cov ntshav siab. Txhim kho kev noj qab haus huv nrog atherosclerosis. Kev noj tshuaj yog txwv thaum cev xeeb tub thiab thaum lactation. Nws raug nqi 200 rubles.
4. Omega Ntxiv TxojCov. Ib qhov ua tiav ntawm Omega acids ntawm hom 3 thiab 6. Kuaj cov haujlwm ntawm cov hlab plawv plawv. Tsis pub tsim los ntawm cov ntshav txhaws. Cov tshuaj muaj tau kuaj mob saib tsis tau. Tus nqi nyob rau hauv Russia yog 330 rubles.
5. Dioscorea NtxivCov. Lowers ntshav cov roj cholesterol thiab txo qis ntshav siab. Tiv thaiv cov hlab ntshav ntawm kev puas tsuaj. Tag nrho-natural muaj pes tsawg leeg. Nws raug nqi txog 250 rubles.

Belarusian generics

Belarusian generics tsis pheej yig. Cov no yog cov sib hloov ze nrog cov khoom sib txawv thiab cov txheej txheem sib thooj ntawm cov neeg mob lub cev.

Lwm cov lus piv txwv txawv teb chaws

Cov tshuaj ntshuam muaj nqi ntau dua. Txoj kev xaiv zoo tshaj plaws rau txhua kis yog tus neeg. Qhov kev txiav txim siab zoo dua yog coj ua ke nrog kws kho mob. Atoris txhais txawv lawv tus kheej cov yam ntxwv.

• VasilipCov. Nws tau tsim nyob rau hauv Slovenia. Haum rau cov neeg mob ntshav qab zib. Kuaj roj, tab sis tsuas yog noj zaub mov. Nyob ntawm seb muaj pes tsawg ntawm cov tshuaj hauv pob, nws raug nqi los ntawm 160 txog 340 rubles.
• ZokorCov. Nws yog tsim nyob rau hauv Netherlands. Kev noj cov tshuaj yuav yog qhov tsim nyog thaum muaj qhov pheej hmoo siab heev ntawm kev muaj kab mob plawv. Tshuaj nqi tus nqi 750 rubles.
• Neeg CoobCov. Ua hauv UK. Haum rau cov neeg mob atherosclerosis lossis ntau hom hypercholesterolemia.Tus nqi ntawm ib cov tshuaj ntawm ntau cov tshuaj nws txawv ntawm 700 txog 3600 rubles.
• RosulipCov. Ua hauv Hungary. Tsis pub tsim los ntawm cov nyiaj tso cia cov cholesterol. Nws raug tso tawm tsuas yog ntawm cov tshuaj noj. Ib qho tshuaj sib txawv ntawm cov ntsiav tshuaj tus nqi ntawm 700 txog 1200 rubles.
• MertenilCov. Nws yog tsim nyob rau hauv Hungary. Qhov cuam tshuam rau cov menyuam yaus nrog cov tshuaj no tseem tsis tau kawm thiab nws raug txwv tsis pub coj mus rau cov menyuam yaus. Ntau qhov ntau yog nyob ntawm kev muag, lawv tus nqi pib txij 700 rubles thiab nce mus txog 1400 rubles.
• RosucardCov. Czech koom pheej Cov tshuaj muaj pes tsawg leeg suav nrog kev ua haujlwm nquag tshuaj rosuvastatin. Kev thov muaj peev xwm ua tau tsuas yog tom qab teem caij kws kho mob. Cov tshuaj pheej pheej pheej yig, nws tus nqi tsis tshaj 500 rubles.

Yuav ua li cas los hloov atoris yog qhov yooj yim daws. Muaj ntau ntau yam analogues. Lawv cov nqi sib txawv, cov npe ntawm cov cim taw qhia yog txawv, muaj cov tshuaj nrog cov txheej txheem ntawm lub cev, muaj cov lus qhia ncaj qha.

Cov tshuaj tsim nyog zoo tshaj plaws xaiv tom qab ntau ntawm kev tshawb fawb tsim nyog hauv kev kuaj lossis chaw soj ntsuam.

Atoris ntsiav tshuaj: cov lus qhia rau kev siv, kev phiv, analogues, tus nqi, tshuaj xyuas

Cov tshuaj Atoris, cov lus qhia rau kev siv uas tau muab rau peb cov neeg nyeem, nyob rau hauv qeb ntawm lipid-txo cov tshuaj, uas yog lub cim thib peb ntawm statins - tshuaj uas pab txo qis cov tshuaj lipoproteins tsawg (LDL) - qhov hu ua "cov roj (cholesterol) tsis zoo" - hauv cov qog cell, cov ntaub so ntswg thiab cov chaw siv roj ntsha ( ntshav, lymph, cerebrospinal kua, synovial thiab interstitial kua) ntawm tib neeg lub cev.

Kev siv cov tshuaj ntawm hom no txo ​​txoj kev ntxim nyiam ntawm cov hlab plawv hauv cov neeg mob ntawm cov hnub nyoog nruab nrab, txawm hais tias nyob rau cov tib neeg laus dua li xya caum xyoo cov qauv no tsis yog li hais tawm.

Lub cuab yeej raug pom zoo rau kev siv tsuas yog thaum muaj kev tiv thaiv kev tiv thaiv kev tiv thaiv (ua raws li cov roj ntsha muaj roj tsawg, kev ua kis las tsis tu ncua thiab kev ua si kom txo lub cev qhov hnyav) tsis tau pab txhawb rau qhov qub ntawm lipid metabolism.

Cov ntaub ntawv ntawm cov sib xyaw ua ke, daim ntawv tso tawm thiab ntim khoom

Atoris muaj ib daim ntawv tsuas tshuaj noj thiab muaj nyob hauv daim ntawv dawb - me ntsis biconvex - puag ncig ntsiav tshuaj nrog cov zaj duab xis txheej. Cov tshuaj phiv tshuaj ntawm cov tshuaj no yog atorvastatin.

Nws cov ntsiab lus hauv txhua cov ntsiav tshuaj tuaj yeem yog: 10, 20, 30, 40, 60 thiab 80 mg.

Lwm cov tshuaj tiv thaiv ntawm cov tshuaj lom neeg muaj npe tau nthuav tawm:

• Microcrystalline cellulose,
• Sodium lauryl sulfate,
• Magnesium stearate,
• Calcium carbonate
• Lactose sib tham,
• Povidone
• Crospovidone
• Croscarmellose sodium.

Tus Opadry II zaj duab xis sheath yog tsim los ntawm:

• Talc,
• Titanium dioxide (khoom noj ntxiv E171),
• Polyethylene glycol (hauv qee qhov chaw nws hu ua macrogol-3000 lossis khoom noj ntxiv E1521),
• Cawv polyvinyl.

Lub hauv paus tseem ceeb ntawm cov ntsiav tshuaj ntawm qhov txhaum thiaj li zoo li cov tshuaj dawb uas muaj qhov ntxhib. Txo cov pob khoom me me (cov hlwv) nrog cov ntsiav tshuaj tso rau hauv cov thawv ntawv los qhia.

Ua raws feem loj ntawm cov tshuaj nquag, txhua pob ntawv yuav muaj li ntawm kaum txog rau cuaj caum ntsiav tshuaj. Cov lus qhia rau kev siv yuav tsum muaj ntim rau hauv txhua pob nrog cov tshuaj.

Cov chaw muag tshuaj

Cov tshuaj atoris, uas zwm rau cov pab pawg ntawm statins, muaj qhov tshaj tawm lipid-txo qis vim qhov muaj peev xwm ntawm nws txoj kev ua haujlwm tseem ceeb, atorvastatin, los tiv thaiv (qeeb qeeb) kev ua haujlwm ntawm cov enzyme tshwj xeeb (HMG-CoA reductase), uas koom nrog cov theem pib ntawm cov roj ntshav hluav taws xob ua haujlwm los ntawm daim siab hlwb (hepatocytes )

Ua tsaug rau kev cuam tshuam ntawm atorvastatin, cov roj cholesterol ua los ntawm hepatocytes yog txo qis, muab kev cuam tshuam rau thaum pib ntawm qhov kev rov qab ua kom ntau ntxiv ntawm cov LDL receptors nrog rau kev ntes ib txhij thiab siv cov roj lipoprotein tsawg nyob rau hauv cov ntshav.

Hauv qhov no, cov metabolism ntawm lipoproteins, uas suav nrog apolipoprotein - apoB protein, uas yog cov neeg nqa khoom ntawm cov "cholesterol" phem thiab tau lees paub los ntawm LDL cov kab mob siab hauv lub siab, kuj nce ntxiv.

Raws li cov txheej txheem saum toj no, cov thooj ntawm cov lipoprotein tsawg ntom, ib zaug khi, tom qab qee lub sijhawm raug tshem tawm ntawm cov ntshav ntshav, uas txhais tau hais tias nws tseem cia li txo qis cov qog lipoprotein tsawg.

Raws li qhov tshwm sim ntawm cov nyhuv no tshwm sim:

• Kev tsuj ntawm kev rov ua dua ntawm cov tshuaj ntuj - isoprenoids tsim nyob rau hauv tib neeg lub cev los ntawm acetic
• Acids thiab kev loj hlob-txhawb cov qauv ntawm tes los ua cov ntawv mos rau hauv lub hlwb.
• Ua kom muaj zog ntawm cov endothelium-so so ntawm cov hlab ntsha,
• Txo cov roj triglycerides, apoB protein thiab cov roj lipoprotein tsawg,
• Kev nce siab ntawm cov tshuaj apolipoprotein AI (apoA-I protein) thiab cov lipoproteins ntau ntom, uas yog cov neeg nqa "cov roj (cholesterol) zoo,"
• Txo cov ntshav plasma viscosity
• Lub extinction ntawm cov txheej txheem ntawm coagulation thiab gluing (sib sau ua ke) ntawm platelets,
• Txhim kho cov hemodynamics (kev txav ntawm ntshav los ntawm cov kab mob ntawm cov hlab ntshav los ntawm thaj chaw siab mus rau thaj chaw qis),
• Kev txhim kho ntawm cov ntshav coagulation system,
• Kev txwv cov kev ua haujlwm ntau dhau ntawm cov macrophages (cov hlwb ua lub luag haujlwm rau kev ntes thiab ua cov kab mob, cov kab mob tuag thiab qhov chaw nyob rau hauv lub cev), uas yuav pab tiv thaiv kom txhob muaj cov kua muag los ntawm cov ntawv ua hu ua atherosclerotic plaques.

Thawj qhov tshwm sim ntawm atorvastatin raug pom tom qab ob lub lim tiam ntawm kev noj tshuaj, nce mus txog qhov siab tshaj plaws tom qab ib hlis. Hauv chav kawm ntawm kev kho mob, nws tau ua pov thawj tias atoris yog cov ntsiav tshuaj uas koj tuaj yeem txo qhov kev pheej hmoo ntawm ischemic, qhov xav tau rov qab mus pw hauv tsev kho mob ntawm cov neeg mob thiab cov neeg tuag.

Cov Tshuaj Pharmacokinetics

• Qhov siab tshaj plaws ntawm cov tshuaj atoris hauv cov ntshav ntshav yog pom 1-2 teev tom qab noj cov ntsiav tshuaj.
• Cov tshuaj pharmacokinetics ntawm atorvastatin tsis nyob ntawm poj niam txiv neej lossis lub hnub nyoog ntawm cov neeg mob.
• Nws tau pom tias nyob rau hauv lub cev ntawm cov neeg mob kev txom nyem los ntawm kev haus dej cawv ntawm daim siab, tus nqi ntawm kev tshwm sim ntawm qhov siab tshaj plaws ntawm atorvastatin tuaj yeem yog kaum rau zaus siab dua li cov cai.
• Tom qab noj mov, tus nqi ntawm qhov nqus (nqus dej) ntawm cov tshuaj tsawg dua me ntsis, txawm hais tias qib ntawm cov roj lipoprotein tsawg yuav tsis hloov txhua.
• Txoj kev noj qab haus huv ntawm atorvastatin, uas ua ntej dhau los ntawm tus neeg mob daim siab, nws tsis tshua muaj: nws tsis ntau tshaj 12% (qhov no tau piav qhia los ntawm kev siv ntawm cov txheej txheem ntawm metabolic). Lub kaw lus bioavailability ntawm lub inhibitory nyhuv ntawm atorvastatin ntawm HMG-CoA reductase ze rau 30%.
• Cov kev sib raug zoo ntawm cov tshuaj nquag ntawm cov tshuaj atoris nrog cov ntshav plasma protein yog 98%.
• Atorvastatin tsis kov yeej cov ntshav-hlwb teeb meem, nws cov metabolism hauv feem ntau tshwm sim hauv cov qauv ntawm daim siab uas raug rau cytochrome P4503A4. Pharmacologically nquag metabolites tsim los ua cov txiaj ntsig ntawm cov txheej txheem no muab qhov loj (kwv yees li 70%) ib feem ntawm qhov kev siv tshuaj ntawm cov tshuaj Atoris, uas kav ntev li nees nkaum rau peb teev.
• Ib nrab-lub neej ntawm cov tshuaj no yog kwv yees li kaum plaub teev. Feem ntau ntawm cov tshuaj tawm hauv tus neeg mob lub cev nrog cov kua tsib, me dua (ze li 45%) - nrog quav. Nrog rau cov zis, tsis pub ntau tshaj 2% ntawm cov tshuaj tau tso tawm.

Atoris - analogues

Txo cov qib triglycerides, lipids thiab cov roj cholesterol hauv ntshav ntshav, statins yog tshuaj. Atoris tseem hais txog lawv - cov tshuaj analogues ntawm cov tshuaj yuav tsum muaj thaum tsis txaus siab rau cov tshuaj no lossis yog tias, rau qee qhov, nws tsis tuaj yeem yuav nws. Nws yog tsim nyog sau cia tias ntau cov generics muaj ntau pheej yig dua.

Analogues ntawm cov tshuaj Atoris

Qhov npaj tau nthuav tawm yog tsim los ntawm atorvastatin calcium - ib yam khoom tsim los txo cov kev kub siab ntawm cov lipids hauv cov ntshav. Atoris tseem ua cov tshuaj antisclerotic rau ntawm cov phab ntsa ntawm cov hlab ntshav, txo cov viscosity thiab ntom ntawm ntshav, txhim kho hemodynamics, thiab txo qhov kev pheej hmoo ntawm kev tsim kab mob plawv.

Cov tshuaj hauv qab no muaj cov txiaj ntsig zoo thiab muaj pes tsawg leeg:

• Torvalip
• Tulip
• Keebkwm
• Liptonorm,
• Thorvacard
• TG-tor
• Torvazin
• Atorvastatin
• Liprimar
• Atorvox
• Lipoford
• Vazator
• Lipona
• Amvastan
• Astin Neeg
• Atocor
• Cov Atorvacor
• Atotex
• Atorvasterol,
• Atormak
• Lipodemin,
• Limistin
• Lipimax
• Vasocline
• Livostor
• Torvazin
• Lithuania,
• Khawv Koob
• Etset,
• Torzaks,
• Actastatin
• Abitor
• Aztor
• Liperosis
• Thaub laus
• Escolan
• Emstat
• Torvadak
• Lipitin
• Atrok.

Qhov twg yog qhov ua tau zoo dua thiab ua haujlwm zoo dua - Atoris lossis Torvakard?

Ob qho tshuaj nyob rau hauv kev txiav txim siab tau txiav txim siab los ntawm tib yam muaj txiaj ntsig, qhov sib xyaw ua ke ntawm cov khoom xyaw ntxiv kuj zoo ib yam. Cov kws kho plawv ntseeg tias tsis muaj qhov sib txawv ntawm cov tshuaj, qhov sib txawv ntawm tus nqi yog tias Torvard yog me ntsis pheej yig dua, txawm tias qhov siab tshaj (40 mg).

Qhov twg yog qhov zoo dua mus yuav - Atorvastatin lossis Atoris?

Cov tshuaj no tseem muaj qhov muaj pes tsawg leeg, tso tawm hauv daim ntawv thiab cov ntsiab lus ntawm cov tshuaj. Atorvastatin feem ntau nyiam, vim tias nws zoo dua tiv thaiv thiab ua rau muaj kev cuam tshuam tsawg dua. Hauv qhov xwm txheej no, tus neeg sawv cev yog tus neeg siv nyiaj ntau dua li Atoris, uas tau piav qhia los ntawm qib siab ntawm kev ua kom huv ntawm cov tshuaj ntawm cov ntsiav tshuaj.

Krestor lossis Atoris - qhov twg zoo dua?

Thawj cov tshuaj qhia tau raws li lwm cov tshuaj - rosuvastatin. Nws ua haujlwm zoo ib yam li Atoris, tab sis kwv yees qhov tshuaj tsawg dua, vim tias 5 mg ntawm rosuvastatin sib raug rau lub zog ntawm 10 mg ntawm atorvastatin.

Yog li, Krestor tau suav hais tias yog ib qho tshuaj yooj yim dua, uas tuaj yeem siv sij hawm tsawg dua. Nyob rau tib lub sijhawm, nws raug nqi ntau dua li Atoris, txog 2.5 npaug.

Zoo tshaj Atoris lossis Liprimar, thiab dab tsi yog qhov zoo dua los yuav?

Cov tshuaj siv sib piv tau ua rau lub hauv paus ntawm atorvastatin. Ntawm qhov zoo ntawm Liprimar nws yog ib qho tsim nyog sau cia:

• cov tshuaj loj dua (10, 20, 40 thiab 80 mg),
• zoo tshuaj ntxuav cov khoom xyaw, uas muab kev pheej hmoo tsawg heev rau cov kev mob tshwm sim,
• zoo thev taus
• siab bioavailability thiab yooj yim.

Txawm li cas los xij, Liprimar tsis tshua muaj tshuaj vim los ntawm tus nqi siab, nws yog 4.5 npaug tshaj li Atoris.

Dab tsi yog qhov zoo rau haus - Atoris lossis Simvastatin?

Cov tshuaj thov muaj cov khoom siv sib txawv, thiab kom ua tiav cov txiaj ntsig xav kom zoo ntawm simvastatin, 20 mg yuav tsum ua tiav, thaum atorvastatin yuav tsum 10 mg.

Tsis muaj qhov sib txawv ntawm cov tshuaj, tshwj tsis yog rau lawv cov nqi. Atoris raug nqi li 4 npaug kim. Thaum xaiv nruab nrab ntawm nws thiab Simvastatin nws yog ib qho tseem ceeb uas yuav tsum tau coj mus rau hauv tus kheej tus yam ntxwv ntawm tus neeg mob, muaj kev tsis haum tshuaj thiab muaj qhov cuam tshuam rau cov tshuaj ntawm cov tshuaj.

Roxer lossis Atoris - uas yog ib qho zoo?

Cov tshuaj sib xyaw nrog cov tshuaj no kuj tseem txawv, roxuvastatin yog lub hauv paus ntawm Roxers. Raws li twb tau hais lawm, cov tshuaj no yog qhov zoo dua, vim tias nws ua tau zoo dua, tsis tas yuav tsum tau tswj hwm ntau zaus thiab noj tshuaj ntau. Ntau tus kws kho mob tau sau ntawv rau Roxer ntau dua, vim tias cov tshuaj no, ntxiv rau kev ua haujlwm zoo, nws pheej yig heev, nws yog 2 zaug pheej yig dua li Atoris.

Atoris analogues thiab nqi

Ua ntej pib txoj kev kho mob nrog Atoris®, tus neeg mob yuav tsum yog tus kws kho mob hypocholesterolemic noj cov zaub mov, uas nws yuav tsum ua raws lub sijhawm kho tag nrho.

Kev nce ntxiv ntawm kev ua si ntawm hepatic enzymes hauv ntshav cov ntshav tuaj yeem pom thaum lub sijhawm kho Atoris®. Qhov nce no feem ntau me me thiab tsis muaj qhov tseem ceeb hauv lub chaw kuaj mob.

Txawm li cas los xij, nws raug nquahu kom soj ntsuam kev ua haujlwm ntawm daim siab enzymes hauv cov ntshav cov ntshav ua ntej kev kho mob, tom qab 6 thiab 12 lub lis piam thiab nrog kev nce ntxiv ntawm koob tshuaj atorvastatin.

Yog tias muaj qhov peb-zaug ntxiv hauv kev ua ntawm ACT thiab / lossis ALT tus txheeb ze rau HBV, kev kho nrog Atoris® yuav tsum tsis ua ntxiv.

Atorvastatin tuaj yeem ua rau nce ntawm kev ua ntawm CPK thiab aminotransferases.

Hauv cov poj niam ntawm lub hnub nyoog yug me nyuam uas tsis siv kev tswj kom tsis pub muaj txiaj ntsig, kev siv Atoris® tsis pom zoo. Yog tias tus neeg mob npaj lub cev xeeb tub, nws yuav tsum tsum tsis txhob noj Atoris® tsawg kawg ib hlis ua ntej lub sijhawm npaj xeeb menyuam.

Cov neeg mob yuav tsum tau ceeb toom tias lawv yuav tsum sab laj nrog kws kho mob sai sai yog tias tsis hnov ​​qhov mob lossis cov leeg tsis muaj zog. Tshwj xeeb yog hais tias lawv nrog tus mob malaise lossis kub taub hau.

Kev kho mob nrog Atoris® tuaj yeem ua rau myopathy, uas qee zaum nrog rhabdomyolysis, ua rau lub raum tsis ua haujlwm.

Txoj kev pheej hmoo ntawm cov kev mob hnyav no nce ntxiv thaum noj ib lossis ntau dua ntawm cov tshuaj hauv qab no nrog Atoris®: fibroic acid derivatives, niacin, cyclosporine, nefazodone, qee cov tshuaj tua kab mob, azole antifungals, thiab HIV tiv thaiv kab mob tiv thaiv.

Hauv kev soj ntsuam cov tsos mob ntawm tus mob myopathy, nws tau pom zoo tias ntshav ntau ntawm CPK raug txiav txim siab. Nrog kev nce siab 10 npaug ntawm VHF kev ua haujlwm ntawm KFK, kev kho mob nrog Atoris® yuav tsum tsis ua mus ntxiv.

Muaj cov ntawv tshaj tawm txog kev txhim kho ntawm atonic fasciitis nrog kev siv atorvastatin, txawm li cas los xij, kev sib txuas nrog kev siv cov tshuaj yog ua tau, tab sis tseem tsis tau muaj pov thawj, tus etiology tseem tsis tau paub.

Cov neeg mob yuav tsum tau ceeb toom tias lawv yuav tsum tau sab laj nrog kws kho mob tam sim ntawd yog tias tsis hnov ​​qhov mob lossis cov leeg tsis muaj zog, tshwj xeeb yog tias lawv nrog mob lossis kub taub hau.

Atoris® muaj lactose, thiab yog li ntawd nws siv los ntawm cov neeg mob uas tsis muaj lactase, lactose intolerance thiab glucose-galactose malabsorption syndrome yog contraindicated.

Cuam Tshuam rau kev muaj peev xwm tsav tsheb thiab ua haujlwm nrog tshuab.

Muab cov tseem muaj kiv taub hau, ceev faj yuav tsum tau siv thaum tsav tsheb thiab lwm cov cuab yeej ua haujlwm uas yuav tsum muaj kev mloog zoo thiab ceev ntawm lub cev kev xav.

Atoris: cov lus qhia rau kev siv, analogues thiab tshuaj xyuas

Atorvastatin txo ntshav plasma cov ntshav qab zib thiab lipoprotein ntau ntau los ntawm inhibiting GMC-CoA reductase, thiab tom qab ntawd, biosynthesis cov roj cholesterol nyob rau hauv lub siab, thiab tseem nce tus naj npawb ntawm hepatic LDL receptors nyob rau ntawm tes, uas ua rau kom muaj kev nce siab thiab LDL catabolism.

Txo LDL kev tsim thiab cov naj npawb ntawm LDL hais. Atoris ua rau muaj qhov qhia tau zoo thiab tsis tu ncua nyob rau hauv qhov kev ua haujlwm ntawm LDL receptors nrog kev hloov pauv uas muaj txiaj ntsig zoo hauv LDL cov kab mob uas nthuav tawm.

Zoo txo ​​LDL cov roj cholesterol hauv cov neeg mob homozygous tsev neeg hypercholesterolemia, thiab qhov no yog pab pawg uas tsis tau teb tas li rau kev kho hypolipidemic.

Hauv cov lus yooj yooj yim, txoj kev siv Atoris pab nres qhov kev tsim cov roj cholesterol hauv lub cev, txo qis cov roj lipoprotein tsawg hauv lub siab.

Kev kho mob nyhuv ntev li 2 lub lis piam tom qab pib siv tshuaj yeeb, qhov siab tshaj plaws tau tiav tom qab 4 lub lis piam. Ua ntej pib kev kho mob, tus neeg mob yuav tsum pauv mus rau kev noj cov zaub mov lipid, uas yuav tsum pom thaum lub sijhawm kho cov tshuaj.

Atoris muaj nyob rau hauv ntsiav tshuaj daim ntawv nrog atorvastatin hauv ib lub ntim ntawm 10, 20 thiab 40 mg rau ib ntsiav tshuaj.

Kev ntsuas rau siv

Dab tsi pab Atoris los ntawm? Qhia cov tshuaj hauv cov kis hauv qab no:

• rau kev kho mob ntawm cov neeg mob uas muaj thawj (hom 2a thiab 2b) thiab sib xyaw hyperlipidemia.
• kev tswj hwm ntawm cov tshuaj yog qhia rau cov neeg mob nrog tsev neeg homozygous hypercholesterolemia nrog nce: cov roj (cholesterol) feem ntau, cov roj lipoprotein tsawg, cov roj triglyceride lossis apolipoprotein B.

Cov lus qhia rau kev siv Atoris, ntau npaum li cas

Cov tshuaj tau noj ntawm qhov ncauj, tsis hais noj mov.

Qhov pom zoo kom pib lub koob tshuaj yog 1 ntsiav tshuaj ntawm Atoris 10 mg txhua hnub. Raws li cov lus qhia, qhov ntau npaum li cas ntawm cov tshuaj txawv ntawm 10 mg rau 80 mg ib hnub ib zaug, thiab raug xaiv coj mus rau hauv tus lej theem pib ntawm LDL-C, lub hom phiaj ntawm txoj kev kho thiab cov txiaj ntsig kho tus kheej. Qhov ntau npaum li cas ntawm cov tshuaj yog xaiv los ntawm tus kws kho mob mus koom, suav rau hauv cov txiaj ntsig ntawm kev tshuaj ntsuam thiab theem pib ntawm cov roj (cholesterol).

Thaum pib kho thiab / lossis thaum qhov nce ntxiv, nws yog qhov yuav tsum tau saib xyuas cov ntshav lipid cov ntsiab lus txhua 2-4 lub lis piam thiab kho qhov tshuaj raws li.

Hauv thawj (cov kab mob heterozygous muaj keeb thiab polygenic) hypercholesterolemia (hom IIa) thiab sib xyaw hyperlipidemia (hom IIb), kev kho mob pib nrog kev pom zoo pib koob, uas tau nce ntxiv tom qab 4 lub lis piam nyob ntawm tus neeg mob cov lus teb. Qhov nyiaj pab ntau tshaj txhua hnub yog 80 mg.

Rau cov neeg laus neeg mob thiab cov neeg mob lub raum uas lub raum tsis ua haujlwm, tsis tas yuav hloov kho dua.

Hauv cov neeg mob uas lub siab tsis ua hauj lwm zoo, cov tshuaj yog tshuaj nrog kev ceev faj hauv kev sib txuas nrog kev ua kom qeeb ntawm kev tshem tawm cov tshuaj tawm hauv lub cev.

Sab sij huam

Raws li cov lus qhia rau kev siv, kev teem sij hawm ntawm Atoris tuaj yeem nrog cov tshuaj phiv no:

• Ntawm lub siab ntsws: kev nyuaj siab, pw tsaug zog, suav nrog insomnia thiab npau suav phem.
• Los ntawm kev tiv thaiv kab mob: kev ua xua, anaphylaxis (suav nrog kev poob siab anaphylactic).
• Cov kab mob hauv lub cev: hyperglycemia, mob ntshav qab zib, rog phaus, tsis nco qab, mob ntshav qab zib mellitus.
• Los ntawm cov kab ke deev thiab qog mammary qog: kev sib deev ua tsis tiav, impotence, gynecomastia.
• Los ntawm cov kab mob hauv lub cev: mob taub hau, paresthesia, kiv taub hau, hypesthesia, dysgeusia, amnesia, peripheral neuropathy.
• Los ntawm cov kab mob ua pa: interstitial mob ntsws, mob caj pas thiab larynx, txhaws ntswg.
• Cov kab mob sib kis thiab mob: nasopharyngitis, mob txeeb zig.
• Los ntawm cov kab ke ntshav thiab cov kab mob lymphatic: thrombocytopenia.
• Los ntawm sab ntawm lub cev ntawm kev pom kev: qhov muag plooj tsis pom kev, pom kev tsis hnov ​​lus.
• Los ntawm cov hlab plawv system: mob hlab ntsha tawg.
• Ntawm ib feem ntawm cov khoom hnov: tinnitus, hnov ​​lus tsis zoo.
• Los ntawm cov hnyuv plab hnyuv: cem quav, pom pob, mob plab, xeev siab, raws plab, ntuav, mob nyob rau sab saud thiab hauv qab plab, ntuav, mob caj pas.
• Los ntawm kab mob hepatobiliary: kab mob siab, mob cholestasis, mob siab.
• Nyob rau ntawm daim tawv nqaij thiab subcutaneous cov ntaub so ntswg: urticaria, tawv nqaij ua pob khaus, khaus, alopecia, angioedema, mob tawv nqaij dermatitis, suav nrog exudative erythema, Stevens-Johnson syndrome, tshuaj lom epidermal necrolysis, mob caj dab txhaws.
• Los ntawm cov leeg mus rau hauv lub cev: myalgia, mob pob txha caj qaum, mob tes taw, mob nqaij ntshiv, mob pob qij txha, mob nraub qaum, mob caj dab, mob leeg tsis muaj zog, myopathy, myositis, rhabdomyolysis, mob leeg (qee zaum kuj nyuaj los ntawm nqaij leeg).
• Cov teeb meem nquag: malaise, asthenia, mob hauv siab, peripheral edema, nkees, ua npaws.

Cov Yuav Tsum Muaj

Atoris yog contraindicated nyob rau hauv cov nram no:

• kev tsis qaug rau cov tshuaj,
• galactosemia,
• malabsorption ntawm qabzib galactose,
• lactose tsis txaus,
• mob raum,
• cov leeg pob txha pathology,
• cev xeeb tub
• pub niam mis
• hnub nyoog txog 10 xyoo.

Xyuam xim yuav tsum tau haus dej cawv, kab mob siab. Pab pawg no tseem suav nrog cov neeg uas lawv cov haujlwm tshaj lij muaj feem cuam tshuam rau kev tsav tsheb thiab cov txheej txheem nyuaj.

Noj ntau dhau

Yog tias dhau ntawm kev siv tshuaj ntau dhau, tsim nyog yuav tsum muaj cov tsos mob thiab kev txhawb nqa kev kho mob. Nws yog ib qho tsim nyog los tswj lub siab ua haujlwm thiab CPK kev ua haujlwm hauv cov ntshav dej. Hemodialysis tsis muaj txiaj ntsig. Tsis muaj ib qho tshuaj tua kab mob tshwj xeeb.

Atoris analogs, tus nqi hauv cov chaw muag tshuaj

Yog tias tsim nyog, Atoris tuaj yeem hloov nrog ib qho tshuaj tiv thaiv ntawm cov tshuaj nquag - cov no yog cov tshuaj:

Thaum xaiv cov analogues, nws yog ib qho tseem ceeb kom nkag siab tias cov lus qhia rau kev siv Atoris, tus nqi thiab tshuaj xyuas cov tshuaj uas muaj cov txiaj ntsig zoo sib xws tsis siv. Nws yog ib qho tseem ceeb kom kws kho mob sab laj thiab tsis txhob hloov pauv cov tshuaj ywj siab.

Khaws ntawm qhov kub thiab txias tsis tshaj 25 ° C. Txee lub neej yog 2 xyoos. Hauv cov khw muag tshuaj, nws raug muag los ntawm cov tshuaj noj.

Muaj ntau qhov kev txheeb xyuas txog Atoris, raws li ntau tus hais tias tus nqi siab ntawm cov tshuaj tau muab pov thawj los ntawm nws cov hauj lwm zoo thiab kam rau ua tau zoo.

Nws raug sau tseg tias thaum kho, cov lus qhia ntawm tus kws kho mob hais txog kev noj haus thiab kev siv lub cev, thiab thaum xaiv thiab kho lub koob tshuaj, cov tshuaj lipoproteins tsawg tsawg yuav tsum tau siv.

Raws li qee tus neeg siv, cov tshuaj tsis muaj qhov tsim nyog kho tau thiab muaj qhov ua tsis tau zoo, ua rau muaj kev tsis zoo.

Atoris analogues yog pheej yig dua

Txo cov qib ntawm lipids hauv cov hlab ntsha, cov kws kho mob siv ntau yam tshuaj, ntawm cov Atoris thiab nws cov analogues nrov heev. Lawv nrhiav kev txo cov ntshav siab hauv cov roj ntshav, thiaj li txhim kho txoj kev noj qab haus huv tag nrho ntawm ib tus neeg.

Hais txog yeeb tshuaj

Atoris ntsiav tshuaj yog tsim hauv Slovenia. Cov tshuaj no yog koom nrog cov xwm txheej ntawm "statins" thiab yog cov kws kho mob rau cov neeg mob kom txo qis cov lipoproteins tsawg (cov roj txaus phom sij) hauv lub cev.

Atorvastatin yog lub ntsiab sib txuas ntawm cov tshuaj. Kev nkag los ntawm cov ntshav mus rau hauv lub lumen ntawm lub siab, atorvastatin nres ua ke ntawm cov roj uas txhaws los ntawm cov qog hlwb.

Tawm tsam cov keeb kwm yav dhau los no, hauv lub cev pib siv cov lipoproteins uas tau nkag rau hauv cov ntshav, muaj cov lej tsawg.

Raws li qhov txiaj ntsig ntawm qhov no, qhov ua tau zoo ntawm Atoris thiab nws cov analogues, uas muaj cov kev ua haujlwm zoo sib xws, nce ntxiv.

Kev tshem tawm cov atherogenic lipids los ntawm Atoris tsis ua rau sedimentation ntawm tom kawg rau ntawm cov hlab ntsha. Tib lub sijhawm, atherosclerosis tsis tsim thiab cov ntshav txhaws tsis ua. Yog tias ischemia loj zuj zus hauv tib neeg lub cev, kev noj tshuaj Atoris thiab cov tshuaj sib hloov ua rau txo qis ntawm kev pheej hmoo ntawm kev tsim mob hlab ntsha tawg nrog lub plawv nres.

Daim ntawv ntau npaum li cas ntawm Atoris thiab nws cov qauv sib cuam tshuam kev siv ib hom tshuaj raws li kws kho mob tau hais tseg.

Feem ntau, raws li kev mob ntawm lub cev thiab cov hlab plawv, tus kws kho mob txiav txim siab qhov tsim nyog ntawm cov tshuaj txhawm rau txhawm rau txhim kho kev zoo.

Feem ntau feem ntau, Atoris thiab nws cov analogues tau sau tseg nyob rau hauv qhov tsis tshua muaj ntau, vim qhov no txo ​​qhov ntxim nyiam ntawm cov kev mob tshwm sim.

Atoris analogues uas tsis tau qis dua hauv kev ua tau zoo rau kev siv tshuaj nws tus kheej tau siv hauv kev kho mob rau ntau tshaj kaum xyoo. Qhov no yog paub tseeb los ntawm kev txheeb xyuas ntau ntawm kws kho mob thiab cov neeg mob. Nrog hypercholesterolemia, Atoris thiab nws cov analogues tuaj yeem txo cov roj cholesterol mus rau theem uas tsim nyog rau lub sijhawm luv luv, thaum txo lub load rau ntawm lub siab.

Txog hnub, ntau Atoris analogues tau ua tiav cov kws kho mob tau siv los txo cov ntshav hauv cov ntshav siab. Hauv Lavxias, nyob rau ntawm txee ntawm cov khw muag tshuaj, cov tshuaj sib cuam tshuam tau nthuav tawm tsis tsuas yog hauv kev tsim khoom txawv teb, tab sis kuj hauv kev tsim khoom hauv tsev. Txhua Atoris analogue muaj ib qho kev qhia tshwj xeeb thiab hom kev ua, uas tus kws kho mob yuav tsum coj mus rau hauv tus account ua ntej sau ntawv yuav cov tshuaj.

Rosuvastatin

Rosuvastatin yog qhov ncauj ntawm lub teeb liab lossis liab xim. Raws li lub ntsiab nquag khoom sib xyaw yog molecules ntawm rosuvastatin, ntawm ntau qhov ntau. Ntxiv rau nws, cov ntsiav tshuaj muaj:

• stearate magnesium
• hmoov txhuv nplej siab fibers
• colloidal daim ntawv ntawm silicon dioxide,
• hypromellose txoj,
• tshwj xeeb zas
• triacetin
• microcrystalline cellulose,
• titanium dioxide.

Cov kev ua haujlwm nquag ntawm cov ntsiav tshuaj tau piav qhia yog tus cwj pwm los ntawm kev tsuj ntawm kev ua ub no ntawm ib tus neeg enzymes lub luag haujlwm rau kev tsim mevalonate lwg me me hauv lub cev. Ntawm qhov kawg, roj yog sib txuas.

Cov pab pawg ntawm cov tshuaj, uas Rosuvastatin belongs, nres qhov kev sib txuas ntawm mevalonate lwg me me.

Tom qab siv los ntawm nws cov kev ua, cov tshuaj tau tawm hauv qhov tsis txawv ntawm lub cev nrog rau hauv quav.

Cov lipid-txo cov tshuaj analogue, uas yog rosuvastatin, yog kho rau cov neeg mob nrog:

• thawj daim ntawv ntawm hypercholesterolemia,
• hypertriglyceridemia,
• homozygous (tsev neeg) qhov xwm txheej ntawm hypercholesterolemia.

Kev siv tshuaj ntawm cov tshuaj nquag thaum noj ib qho tshuaj ib txwm siv los ntawm kws kho mob txhawm rau txhawm rau txo kev pheej hmoo ntawm kev tsim cov kev tiv thaiv ntawm cov mob atherosclerosis. Rosuvastatin feem ntau yog kho rau cov neeg mob hauv cov laus, txij lub sijhawm no lub lumens ntawm ntau ntawm lawv cov hlab ntsha muaj qhov ntev tshaj plaws, txij li lawv tau daig nrog cov roj (cholesterol).

Tus ntoo khaub lig yog paj yeeb ib puag ncig uas muaj cov calcium ntau ntau rosuvastatin. Nws yog nws leej twg ua lub luag haujlwm ntawm lub ntsiab sib txuas ntawm cov tshuaj. Qhov kev cia siab ntawm cov tshuaj nquag thaum noj Krestor yog tus kws kho mob tau sau tseg, tom qab kev kuaj mob tsim nyog.

Cov tshuaj yog siv tau rau hypercholesterolemia, zoo li rau hypertriglyceridemia.

Tsis tas li, cov tshuaj siv los kho cov ntshav qab zib tsis yog-insulin-mellitus. Kev rhuav tshem ntawm cov tshuaj tshwm sim hauv cov kab mob siab, ua raws los ntawm kev tawm ntawm lub cev.

Nqa ib qho analog yuav tsum tau kos nrog dej me ntsis. Kev ua ntau yam thiab ntau npaum li cas ntawm kev tswj hwm yog kho los ntawm tus kws kho mob tom qab kev kuaj mob tshwj xeeb ntawm cov ntshav ncig ntawm tus neeg mob. Kev siv tshuaj rau nws tus kheej los ntawm Krestor yog qhov txaus ntshai rau kev noj qab haus huv, vim nws tuaj yeem ua rau muaj kev mob tshwm sim thaum noj ntau tshaj.

Cardiomagnyl

Cardiomagnyl yog lwm qhov ntawm Atoris cov analogues. Cov nquag ua haujlwm yog cov lwg me me ntawm acetylsalicylic acid nrog magnesium hydroxide. Ib qho kev nce hauv kev ua ntawm "cov roj (cholesterol) phem hauv cov hlab ntshav qhia txog kev teem caij rau Cardiomagnyl los ntawm tus kws kho mob rau tus neeg mob!

Kev noj cov tshuaj no cuam tshuam nrog kev nce ntxiv ntawm kev muaj mob txoj hlab ntsws hauv lub cev. Qhov no tshwm sim thaum:

• tsis khov ntawm angina pectoris,
• mob ntshav qab zib,
• lub cev nyhav dhau heev lawm
• ntshav siab
• myocardial infarction.

Cardiomagnyl yog contraindicated rau hauv cov neeg kev txom nyem los ntawm:

• ua xua rau yeeb tshuaj,
• mob ntshav roj,
• mob hnyuv los ntshav,
• tsis txaus nyob rau hauv lub cev ntawm K-vitamin,
• erosive thiab ulcerative pathologies sab hauv cov plab hnyuv siab raum,
• mob hnyav lub raum tsis ua hauj lwm.

Cardiomagnyl tsis raug tso cai los ntawm cov neeg raug kev txom nyem los ntawm tus neeg mus rau hauv lub cev ntawm acetylsalicylic acid lwg me me nrog magnesium hydroxide, zoo li thaum cev xeeb tub hauv lub sijhawm lactation.

Simvastatin

Atoris lossis simvastatin ua tau zoo dua? Simvastatin yog ib qho tshuaj tiv thaiv hypolipidemic uas muaj ntau qhov ntau ntawm cov khoom ntawm tib lub npe. Cov tshuaj yog tawm rau cov neeg mob kev txom nyem los ntawm cov ntsiab lus siab ntawm lipid zoo li cov sib txuas hauv cov hlab ntshav.

Raws li qhov tshwm sim, tsis muaj kev tsub zuj zuj ntawm cov tshuaj lom sterol hauv lub cev. Nrog kev ua tau zoo ntawm cov tshuaj, cov tshuaj muaj ib tus nqi siv tau, uas ua rau nws nrov ntawm cov pej xeem. Kev txhim kho ntawm tib neeg myopathy yog lub teeb liab kom tsis txhob noj cov tshuaj no.

Atoris lossis Atorvastatin: nws zoo dua? Ua ntej xaiv ib qho Atoris analogue, koj yuav tsum sab laj nrog koj tus kws kho mob uas, tom qab kev tshuaj xyuas lub cev kom ntxaws, yuav tuaj yeem sau ntawv yuav cov tshuaj kom zoo thiab zoo rau tus neeg mob.

Peb pom zoo nws! Txog kev kho thiab kev tiv thaiv ntawm kev puas ntsoog ntawm kab mob thiab tshaj tawm, peb cov neeg nyeem siv tus qauv ntawm kev kho mob nrawm thiab tsis yog phais mob pom zoo los ntawm cov kws tshaj lij Rheumatologist ntawm Lavxias, uas txiav txim siab tawm tsam kev lag luam tshuaj tsis raug cai thiab nthuav qhia cov tshuaj uas YUAV TSUM TAU! Peb tau paub txog cov txheej txheem no thiab txiav txim siab los muab rau koj kom mloog.

Atoris: cov lus qhia rau kev siv, analogues, nqe, tshuaj xyuas

Atoris yog ib lub npe lag luam tawm rau atorvastatin tsim los ntawm lub tuam txhab Slovenian Krka. Ntawm lwm cov generics, cov tshuaj no sawv zoo nyob rau hauv kev ua tau zoo.

Atoris yog qhov muaj feem yuav txo qis cov roj cholesterol, "lipoproteins" uas tsim kev puas tsuaj, triglycerides, ntxiv rau qhov nce ntawm "lipoproteins zoo.

Cov lus qhia tau qhia tias cov neeg tuaj saib lub hom phiaj ntawm cov tshuaj Atoris yog cov neeg mob hypercholesterolemia, mob plawv (CHD), thiab ntshav qab zib mellitus.

Kev Sau ua ke, daim foos tso tawm

Atoris yog cov ntsiav tshuaj uas muaj 10, 20, 30, 60, lossis 80 milligrams ntawm cov tshuaj nquag. Hloov, convex, dawb. On qhov txhaum - ntom, dawb.

Cov tshuaj muaj txiaj ntsig ntawm Atoris yog atorvastatin calciumCov. Ntxiv rau nws, cov tshuaj muaj nyob nrog: povidone, sodium lauryl sulfate, calcium carbonate, cellulose, lactose monohydrate, croscarmellose, magnesium stearate. Txhua ntsiav tshuaj yog coated nrog Opadry 2.

Atoris: cim qhia rau siv

Ua ntej noj cov tshuaj, tus neeg mob pauv mus rau qhov khoom noj uas txo qis qhov kev tswj hwm ntawm cov cholesterol, LDL cov ntshav. Nws yuav tsum raug pom thoob plaws hauv lub sijhawm kho. Kev tsis quav ntsej cov zaub mov noj kom tsawg los yog nullifies cov hauj lwm zoo ntawm atorvastatin txoj kev kho.

Raws li cov lus qhia, Atoris ntsiav tshuaj siv los kho:

• homo-, heterozygous tsev neeg thiab tsis-tsev neeg hypercholesterolemia,
• tag nrho hyperlipidemia,
• dibetalipoproteinemia,
• tsev neeg hypertriglyceridemia.

Atoris kuj tseem raug kho rau kev tiv thaiv cov kab mob plawv. Vim yog lub zog tiv thaiv atherogenic ntawm cov tshuaj:

• txo cov kev ploj tuag los ntawm kab mob plawv
• txo txoj kev pheej hmoo ntawm lub plawv nres, mob hlab ntsha tawg,
• tiv thaiv angina tawm tsam,
• txo tus naj npawb ntawm cov neeg mob xav tau kev phais mob.

Txoj kev ntawm daim ntawv thov, ntau npaum li cas

Atoris ntsiav tshuaj noj ib zaug / hnub ua ntej yuav mus pw, ua ntej, tom qab lossis nrog zaub mov noj. Nws raug nquahu kom coj cov tshuaj nyob rau tib lub sijhawm.

Vim li cas nws thiaj tseem ceeb uas yuav tsum coj Atoris thaum yav tsaus ntuj? Thaum tsaus ntuj, lub siab ua haujlwm tawm cov roj (cholesterol) siab tshaj plaws. Yog tias koj tsis nco qab noj tshuaj, ua kom sai li sai tau.

Hla ib lub sijhawm yog tsawg dua 12 teev kom txog rau thaum hnub tom ntej. Hauv qhov no, qhov ntau ntawm cov tshuaj tsis tas yuav nce ntxiv.

Cov koob tshuaj pom zoo ntawm cov tshuaj yog 10-80 mg. Thaum xaiv cov tshuaj ntau ntau ntawm Atoris, theem pib ntawm cov roj (cholesterol), LDL, qhov muaj cov teeb meem tsis sib thooj, thiab kev siv lwm yam tshuaj raug suav nrog.

Kev kho mob pib nrog kev noj tshuaj me (10-20 mg). Tom qab plaub lub lis piam, kws kho mob txheeb xyuas qhov kev hloov pauv ntawm cov cholesterol, lipoproteins. Yog tias cov txiaj ntsig xav tau tsis tiav, qhov kev txhaj tshuaj ntawm Atoris yog nce ntxiv. Nrog cov roj (cholesterol) tsawg, cov ntsiav tshuaj muaj qhov qis qis ntawm cov khoom nquag yog kws kho.

Txhawm rau kho cov roj (cholesterol), cov neeg mob uas noj cov tshuaj erythromycin, clarithromycin, lopinavir, ritonavir, Atoris yog cov tshuaj tsis ntau tshaj 20 mg.

Thoob plaws hauv chav kawm ntawm txoj kev kho, nws yog qhov tsim nyog los tswj cov qib roj, LDL, VLDL, triglycerides, mob siab, lub raum kuaj, CC. Qhov no pab ntsuas lub cev lub cev teb rau kev siv Atoris, thiab tseem ceeb toom rau kev txhim kho cov kev mob tshwm sim hauv lub sijhawm.

Kev sib txuam

Kev siv tib lub sij hawm Atoris ntsiav tshuaj nrog rau qee cov tshuaj yog fraught nrog cov txiaj ntsig tsis zoo los yog txo qis ntawm qhov txiaj ntsig ntawm ib qho ntawm lawv.

Cov tshuaj tsis tau sau tseg rau cov neeg uas noj:

• antifungal tshuaj ntawm azole pawg,
• qee cov tshuaj tua kab mob (cyclosporine, telithromycin),
• gemfibrozil
• HIV tiv thaiv kab mob (ritonavir, lopinavir),
• fusidic acid
• haus kua txiv txiv kab ntxwv qaub.

Qee cov tshuaj, thaum noj ua ke nrog Atoris, yuav tsum tau kho ntau npaum li cas. Lawv cov npe yog hauv seem "Txoj kev thov thiab muab npaum li cas."