Thiogammacene, nrhiav, yuav

Lub npe kev lag luam ntawm cov tshuaj: Thiogamma

Lub Npe Tsis Muaj Npe International: Thioctic kua qaub

Daim ntawv noj tshuaj: ntsiav tshuaj, kev daws teeb meem rau infusion administration, mloog zoo rau kev npaj ntawm Txoj kev lis ntshav daws

Yam tshuaj muaj sia: thioctic kua qaub

Cov tshuaj pab pawg kho mob:

lipid thiab carbohydrate metabolism

Cov yam ntxwv Pharmacological:

Cov tshuaj phiv tshuaj Thiogamma (Thiogamma-Turbo) yog thioctic (alpha-lipoic) acid. Thioctic acid tsim nyob rau hauv lub cev thiab pabcuam ua lub coenzyme rau lub zog metabolism ntawm alpha-keto acids los ntawm oxidative decarboxylation. Thioctic acid ua rau cov ntshav qabzib tsawg zuj zus, ua rau cov ncauj lus glycogen ntau zog hauv hepatocytes. Kev ua kom tsis haum plab los yog tsis muaj thioctic acid yog pom nrog ntau qhov ntau ntawm cov metabolites hauv lub cev (piv txwv, ketone lub cev), zoo li thaum intoxication. Qhov no ua rau muaj kev ntxhov siab hauv cov xov aerobic glycolysis. Thioctic acid muaj nyob rau hauv lub cev hauv daim ntawv ntawm 2 daim ntawv: txo thiab oxidized. Ob daim ntawv no yog physiologically dhia, muab cov tshuaj antioxidant thiab anti-toxic los.

Thioctic acid tswj kev ua kom cov metabolism ntawm carbohydrates thiab cov rog, zoo cuam tshuam cov metabolism hauv cov roj cholesterol, muaj cov kab mob hepatoprotective, txhim kho daim siab ua haujlwm. Muaj txiaj ntsig zoo rau kev rov ua dua tus txheej txheem hauv cov nqaij thiab cov plab hnyuv siab raum. Lub zog thaj tsam ntawm thioctic acid zoo ib yam li cov teebmeem ntawm cov vitamins B. Thaum lub sijhawm pib hla lub siab, thioctic acid muaj kev hloov pauv tseem ceeb. Hauv cov tshuaj muaj yees, pom tias cov tib neeg cov kev hloov pauv txawv.

Thaum siv sab hauv, nws yog sai thiab yuav luag nqus los ntawm cov hnyuv. Kev txiav txim siab tau tau nrog cov oxidation ntawm ib sab ntawm cov thioctic acid thiab nws txoj kev txuas. Kev tshem tawm ib nrab-lub neej ntawm Tiogamma (Tiogamma-Turbo) yog los ntawm 10 txog 20 feeb. Tsau tawm hauv cov zis, nrog metabolites ntawm thioctic acid predominating.

Kev taw qhia rau kev siv:

Mob ntshav qab zib polyneuropathy, haus luam yeeb polyneuropathy.

Cov Tshuaj Tiv Thaiv:

Cev xeeb tub, lactation (pub niam mis rau menyuam noj), menyuam yaus hnub nyoog qis dua 18 xyoo, txo tus mob thioctic acid lossis lwm yam tshuaj ntawm cov tshuaj.

Muab thiab kev coj:

Thiogamma rau cov tswj hwm kev ua niam txiv.

Thiogamma yog rau kev tswj hwm los ntawm tsoomfwv los ntawm cov leeg ntshav nrog kua. Rau cov laus, koob tshuaj 600 mg (txheem ntawm 1 vial lossis 1 ampoule) yog siv ib hnub ib zaug. Txoj kev lis ntshav yog nqa tawm maj mam, rau 20-30 feeb. Lub chav kawm ntawm kev kho mob yog kwv yees li 2 txog 4 lub lis piam. Yav tom ntej, kev siv sab hauv ntawm Tiogamma hauv cov ntsiav tshuaj yog qhov pom zoo. Niam txiv cov thawj coj Thiogamma rau Txoj kev lis ntshav yog kho rau mob hnyav ntawm lub rhiab uas cuam tshuam nrog mob ntshav qab zib polyneuropathy.

Cov ntsiab lus ntawm 1 lub raj mis ntawm Thiogamma-Turbo lossis 1 ampoule ntawm Thiogamma (600 mg ntawm cov tshuaj) yog yaj nyob rau hauv 50-250 ml ntawm 0.9% sodium chloride tov. Tus nqi ntawm kev tso ntshav infusion - tsis ntau tshaj 50 mg ntawm thioctic acid hauv 1 feeb - qhov no kwv yees sib raug rau 1.7 ml ntawm Tiogamma tov. Kev noj tshuaj diluted yuav tsum siv tam sim ntawd tom qab sib tov nrog hnyav. Thaum lub sijhawm infusion, txoj kev daws teeb meem yuav tsum muaj kev tiv thaiv los ntawm lub teeb los ntawm cov khoom siv tshwj xeeb lub teeb tiv thaiv.

Cov ntsiav tshuaj yog npaj rau kev siv sab hauv. Nws raug nquahu kom sau ntawv mus rau 600 mg ntawm cov tshuaj 1 zaug nyob rau ib hnub. Cov ntsiav tshuaj yuav tsum nqos tag nrho, noj tsis hais txog zaub mov, ntxuav cia nrog cov dej txaus. Lub sijhawm tiv thaiv kev kho ntsiav tshuaj yog los ntawm 1 mus rau 4 hlis.

Sab sij huam:

Nruab nrab hauv lub paj hlwb: hauv cov tsis tshua muaj tshwm sim, tam sim ntawd tom qab siv cov tshuaj nyob rau hauv daim ntawv ntawm Txoj kev lis ntshav, hla lub cev sib zog tuaj yeem ua tau.

Cov plab hnyuv siab raum: ua txhaum ntawm qhov xav ntawm saj, diplopia.

Hematopoietic system: purpura (mob tawm pob), mob thrombophlebitis.

Cov tshuaj tiv thaiv tsis haum ntshav: lub cev tsis haum tshuaj tuaj yeem ua rau anaphylactic ceeb, eczema lossis urticaria ntawm qhov chaw txhaj tshuaj.

Digestive system (rau Tiogamma ntsiav tshuaj): dyspeptic manifestations.

Lwm tus neeg: yog tias Tiogamma-Turbo (lossis Tiogamma rau kev tswj hwm kev coj noj coj ua) raug tswj hwm sai, kev ua pa nyuaj thiab qhov zoo ntawm qhov tawm tsam hauv lub taub hau yog qhov ua tau - cov kev cuam tshuam no tom qab txo qis rau qhov kev lis ntshav. Kuj tseem ua tau: hypoglycemia, kub tso xim, kiv taub hau, tawm hws, mob hauv lub plawv, txo ntshav qabzib, xeev siab, pom kev plooj, mob taub hau, ntuav, tachycardia.

Kev cuam tshuam nrog lwm cov tshuaj:

Thioctic acid txo cov kev ua haujlwm ntawm cisplatin thaum noj nws, thiab tseem muaj cov tshuaj tiv thaiv uas muaj hlau, xws li hlau, magnesium.

Thioctic acid reacts nrog suab thaj molecules tsim sparingly soluble complex, piv txwv li, nrog kev daws levulose (fructose).

Thioctic acid ua rau lub zog tiv thaiv kev tiv thaiv ntawm GCS.

Nrog rau siv ua ke ntawm thioctic acid thiab insulin los yog tshuaj ntawm qhov ncauj hypoglycemic, lawv cov nyhuv tuaj yeem ua kom zoo dua.

Ethanol thiab nws cov metabolites ua kom tsis muaj zog ntawm thioctic acid.

Qhov thioctic acid infusion solution tsis sib haum nrog kev daws teeb meem dextrose, Lub kua lub suab, thiab nrog cov kev daws teeb meem uas hnov ​​mob nrog disulfide thiab SH pawg.

Hnub tas sij hawm: 5 xyoos

Cov Cai Siv Tshuaj Solos ntawm tshuaj

Chaw tsim tshuaj paus:

Werwag Pharma GmbH & Co. KG (Worwag Pharma GmbH & Co. KG), Beblingen, Lub Tebchaws Yelemees.