Kev siv tshuaj tiv thaiv ntshav qab zib Galvus Met - cov lus qhia rau kev siv
Galvus Met yog cov tshuaj uas muaj suab npe tsis zoo hypoglycemic lub cev. Nws yog siv los ua kom cov ntshav qabzib ntau ntau. Cov tshuaj phiv tshuaj yog vildagliptin. Muaj nyob hauv ntsiav tshuaj daim ntawv.
Cov tshuaj yog tawm rau cov ntshav qab zib hom 2.
- Cov neeg yav tas los kho cov tshuaj monotherapy nrog vildagliptin thiab metformin.
- Nrog rau cov tshuaj tua kab mob, nrog rau kev kho kom zoo thiab lub cev kom noj qab haus huv.
- Thaum pib theem ntawm kev siv tshuaj kho - ua ke nrog metformin. Qhov no yog qhov tshwj xeeb tshaj yog thaum kev noj zaub mov zoo thiab kev tawm dag zog tsis muaj txiaj ntsig.
- Ua ke nrog metformin, insulin, sulfonylurea, nrog rau kev noj zaub mov tsis muaj txiaj ntsig, kev tawm dag zog thiab monotherapy nrog cov tshuaj no.
- Nrog sulfonylurea thiab metformin rau cov neeg mob uas yav dhau los ua ke nrog txoj kev kho nrog cov tshuaj no thiab tsis ua tiav glycemic tswj.
- Ib txhij nrog metformin thiab insulin nrog cov nyiaj tsawg ntawm cov nyiaj no.
Cov Yuav Tsum Muaj
- Kab mob ua pa.
- Ib leeg tsis qaug rau cov tshuaj ntawm cov tshuaj.
- Muaj nuj nqi mob ntawm lub raum.
- Raws plab, ua npaws, ntuav. Cov tsos mob no tej zaum yuav qhia tau qhov ua kom mob raum thiab mob ceev heev.
- Lub plawv tsis ua haujlwm, myocardial infarction thiab lwm yam pathologies ntawm cov hlab plawv system.
- Lub xub ntiag ntawm cov ntshav qab zib lactic acidosis thiab ketoacidosis, tawm tsam keeb kwm ntawm ib lub xeev qub lossis tsis nco qab lawm.
- Cawv muaj yees.
Ib qho ntxiv, cov tshuaj tsis pom zoo siv rau cov hnub nyoog 60 xyoo thiab cov neeg hluas hnub nyoog qis dua 18 xyoo. Cov neeg mob ntawm cov hnub nyoog no muaj peev xwm nkag siab ntau ntxiv rau metformin.
Cov lus qhia rau kev siv
Tsuas tshuaj yog xaiv ib qho zuj zus rau txhua tus neeg mob. Qhov no yuav siv sij hawm mus rau hauv tus account qhov hnyav ntawm tus kab mob, intolerance mus rau Cheebtsam cov tshuaj ntawm cov tshuaj.
Kev Kho Mob Kho Mob | Hauv kev sib xyaw nrog metformin thiab sulfonylurea | Ua ke nrog cov tshuaj insulin, metformin thiab thiazolidinedione | Nrog sulfonylurea |
---|---|---|---|
50 mg ib zaug lossis 2 zaug hauv ib hnub (qhov tshuaj tso cai ntau tshaj yog 100 mg) | 100 mg rau ib hnub | 50-100 mg ib zaug lossis 2 zaug hauv ib hnub | 50 mg ib hnub ib zaug rau 24 teev |
Yog tias cov piam thaj hauv qib siab tsis tau poob qis thaum noj ntau kawg ntawm 100 mg, nws raug nquahu kom noj cov tshuaj hypoglycemic ntxiv.
Kev noj cov tshuaj yog nyob ntawm kev noj haus. Kev txhaj tshuaj ntau dua yog xav tau rau cov neeg mob lub cev tsis ua haujlwm hnyav ntawm lub raum. Qhov siab tshaj plaws yuav tsis pub tshaj 50 mg ib hnub. Rau cov seem ntawm cov neeg mob, tsis tas yuav xaiv cov koob tshuaj.
Sab sij huam
Yog tias siv qhov tsis raug, cov kev mob tshwm sim no:
- bouts ntawm xeev siab thiab ntuav,
- kiv taub hau
- mob taub hau
- gastroesophageal reflux,
- ua daus no
- tshee hnyo
- raws plab lossis quav tawv.
- mob hauv plab
- qog ntshav,
- flatulence
- qaug zog,
- tsis muaj zog
- hyperhidrosis.
Qee cov neeg mob tau pom tias nws yog xim hlau hauv lawv lub qhov ncauj. Qee zaum muaj tawv nqaij ua pob thiab urticaria, ntau dhau ntawm cov tawv nqaij ntawm daim tawv nqaij, ua rau mob tawv nqaij ua pob khaus, thiab muaj cov kua dej ntau dhau rau cov nqaij mos. Mob tej pob txha, mob leeg, paj hlwb tsis muaj peev xwm koom tsis tau.12 thiab kab mob siab (ploj mus tom qab tsis kho kev kho mob).
Cov lus qhia tshwj xeeb
Txhua tus neeg mob uas muaj ntshav qab zib hom 2, nrog rau kev siv tshuaj, nws raug nquahu kom ua raws li kev noj zaub mov nruj. Kev siv calories yuav tsum tsis pub tshaj 1000 tauj ib hnub.
Ua ntej yuav muab tshuaj thiab thaum kho nrog tshuaj, nws yog ib qho tsim nyog yuav tau soj ntsuam daim siab ua haujlwm lub siab. Qhov no yog vim muaj qhov nce ntxiv ntawm kev ua haujlwm ntawm aminotransferase thaum noj vildagliptin.
Nrog kev txuam nrog metformin hauv lub cev, kev txhim kho ntawm cov kab mob lactic acidosis yog qhov yuav tshwm sim. Qhov no yog qhov tshwm sim tsis tshua muaj ntau tab sis hnyav kawg ntawm metabolic. Cov pab pawg muaj xws li cov neeg uas tau tshaib plab ntev los yog tsim txom cawv. Qhov no tseem siv rau cov neeg mob ntshav qab zib raug kev txom nyem los ntawm kev mob raum tsis zoo.
Cev xeeb tub
Galvus Met 50/1000 mg yog contraindicated rau cov poj niam cev xeeb tub thiab lactating. Tsis muaj cov ntaub ntawv qhia txog kev siv cov tshuaj lub sijhawm no.
Hauv kev tshwm sim uas yuav tsum tau siv tshuaj kho metformin, tus endocrinologist yuav xaiv lwm cov tshuaj muaj pov thawj. Hauv qhov no, koj yuav tsum ntsuas ntsuas ntshav qab zib kom txog thaum tsis muaj menyuam. Txwv tsis pub, muaj qhov pheej hmoo ntawm kev txhim kho kev tsis xwm yeem nyob hauv tus menyuam. Nyob rau hauv cov ntaub ntawv phem tshaj, kev muaj me nyuam hauv plab yog tau. Txhawm rau cov piam thaj tsis xwm yeem, ib tus poj niam xav tau txhaj tshuaj nrog insulin.
Yeeb tshuaj sib cuam tshuam
Cov tshuaj muaj qhov tsawg ntawm kev sib txuam nrog tshuaj. Vim qhov no, nws tuaj yeem ua ke nrog ntau yam inhibitors thiab cov enzymes.
Nrog rau kev siv tib lub sijhawm nrog Glibenclamide, Warfarin, Digoxin thiab Amlodipine, tsis muaj kev cuam tshuam loj hauv chaw kho mob.
Galvus Meta muaj ntau cov qauv tshuaj tua kab mob. Ntawm lawv yog Avandamet, Glimecomb, Combogliz Prolong, Januvius, Trazhent, Vipidiya thiab Onglisa.
Ua ke nrog cov tshuaj hypoglycemic. Cov nkauj muaj nrog ob lub ntsiab-rosiglitazone thiab metformin. Nws yog ntawv kho rau kev kho mob ntshav qab zib-insulin. Metformin inhibits lub synthesis suab thaj hauv lub siab, thiab rosiglitazone nce rhiab heev ntawm cov hlwb hlwb ua rau cov kua dej.
Muaj cov gliclazide thiab metformin. Normalizes ntshav qabzib. Contraindicated rau cov mob ntshav qab zib-insulin, cov poj niam cev xeeb tub, kev mob ntshav qab zib thiab cov neeg mob tsis nco qab.
Combogliz Prolong
Cov tshuaj sib xyaw ua ke ntawm cov tshuaj muaj xws li saxagliptin thiab metformin. Tsim los kho mob ntshav qab zib hom 2. Contraindicated nyob rau hauv cov neeg uas muaj insulin-nyob rau hauv daim ntawv ntawm cov ntshav qab zib, cov poj niam cev xeeb tub, cov tub ntxhais hluas hnub nyoog qis dua 18 xyoo. Tsis tas li, Combogliz Prolong tsis tau raug tshuaj rau qhov tsis haum lub cev rau lub ntsiab lus tseem ceeb thiab ua rau lub siab thiab lub raum tsis ua haujlwm.
Sitagliptin ua cov haujlwm tseem ceeb ntawm tus neeg sawv cev hypoglycemic. Cov tshuaj normalizes qib ntawm glucagon thiab glycemia. Nws yog cov mob ntawm cov neeg tsis haum xeeb rau qee yam thiab cov mob ntshav qab zib insulin. Thaum siv tshuaj kho mob, ua pa nyuaj, mob taub hau, mob pob txha, thiab plab zom mov tuaj yeem tshwm sim.
Muaj nyob hauv daim ntawv ntawm cov ntsiav tshuaj nrog linagliptin. Nws ua kom cov ntshav qabzib ntau thiab ua rau lub zog gluconeogenesis. Cov koob tshuaj yog xaiv tau ib tus zuj zus.
Cov tshuaj yog npaj rau kev kho mob sib xyaw lossis monotherapy ntawm hom 2 mob ntshav qab zib. Muaj nyob hauv ntsiav tshuaj daim ntawv. Nws yog txwv tsis pub rau cov neeg muaj lub plawv, lub raum thiab daim siab ua haujlwm, insulin-mob ntshav qab zib thiab mob ntshav qab zib ketoacidosis.
Cov tshuaj yog siv los tswj kev yoo ntshav cov ntshav qab zib thiab tom qab noj mov. Lub saxagliptin uas yog ib feem ntawm kev tswj glucagon. Nws yog siv rau kev kho mob monotherapy lossis hauv kev sib xyaw nrog lwm cov tshuaj. Contraindicated nyob rau hauv hom 1 mob ntshav qab zib thiab ketoacidosis.
Kev txheeb xyuas txog daim ntawv thov yog feem ntau zoo. Galvus Met muaj kev zam txim siab zoo los ntawm yuav luag txhua tus neeg mob. Qhov tsuas yog tsis zoo ntawm cov tshuaj yog nws cov nqi siab. Kuj tseem muaj qhov xav tau ntxiv ntawm kev siv tshuaj txo cov piam thaj.
Cov ntaub ntawv dav dav txog cov tshuaj
Vim qhov tshwm sim ntawm vildagliptin (cov tshuaj ua kom muaj zog), qhov cuam tshuam ntawm peptidase enzyme yuav txo qis, thiab kev sib txuas ntawm glucagon-zoo li peptide-1 thiab HIP tsuas yog nce ntxiv.
Thaum tus nqi ntawm cov tshuaj no hauv lub cev ua rau siab dua li ib txwm, Vildagliptin txhim kho kev ua haujlwm ntawm cov qe ntshav hauv kev sib raug zoo rau cov piam thaj, uas ua rau kev sib ntxiv ntawm cov tshuaj hormones uas txo qis qab zib.
Nws yuav tsum raug sau tseg tias qhov nce ntawm beta-tes haujlwm yog kiag li nyob ntawm tus nqi ntawm lawv qhov kev rhuav tshem. Vim li no, hauv cov neeg uas muaj cov piam thaj li ib txwm, vildagliptin tsis muaj qhov cuam tshuam rau kev tsim cov tshuaj insulin.
Cov tshuaj qaug tshuaj ntawm cov tshuaj tsub kom nce tus nqi ntawm glucagon-zoo li peptide-1 thiab nce rhiab heev ntawm alpha hlwb rau cov kua nplaum. Raws li qhov tshwm sim, glucagon synthesis nce. Kev poob qis hauv nws cov nyiaj thaum lub sijhawm kev noj mov ua rau muaj qhov nce siab ntawm cov hlwb sib luag nrog rau cov tshuaj hormones uas ua kom qab zib.
Kev Sau ua ke, daim foos tso tawm
Cov tshuaj yog nyob rau hauv daim ntawv ntawm ntsiav tshuaj, uas yog txheej. Ib qho muaj ob qho tseem ceeb: Vildagliptin (50 mg) thiab Metformin, muaj nyob hauv peb koob tshuaj - 500 mg, 850 mg thiab 1000 mg.
Ntxiv rau lawv, cov tshuaj muaj pes tsawg leeg raws li:
- magnesium stearic acid,
- hydroxypropyl cellulose,
- hydroxypropyl methyl cellulose,
- talcum hmoov
- titanium dioxide
- hlau oxide daj lossis xim liab.
Cov ntsiav tshuaj tau ntim rau hauv blisters ntawm kaum daim. Cov pob muaj peb lub hlwv.
Cov chaw muag tshuaj thiab tshuaj pharmacokinetics
Cov suab thaj txo qis ntawm cov tshuaj pom tau hais ua tsaug rau qhov kev ua ntawm ob qho tseem ceeb:
- Vildagliptin - nce kev ua haujlwm ntawm cov hlwb pancreatic tiv thaiv cov ntshav qab zib, uas ua rau muaj zog ntau ntxiv ntawm cov tshuaj insulin,
- Metformin - txo cov piam thaj hauv lub cev los ntawm kev txo qis ntawm kev nqus ntawm cov carbohydrates, txo cov synthesis ntawm qabzib los ntawm daim siab ua haujlwm thiab txhim kho kev siv ntawm cov ntaub so ntswg.
Cov tshuaj yog siv los ua rau txo qis cov ntshav qab zib hauv lub cev. Ntxiv mus, hauv qee qhov tsis tshua muaj tshwm sim, kev teeb tsa cov ntshav hauv lub cev ntshav yog sau tseg.
Nws tau pom tias kev noj mov tsis cuam tshuam rau qhov nrawm thiab theem ntawm kev nqus ntawm cov tshuaj, tab sis kev saib xyuas ntawm cov khoom siv cuam tshuam tsawg dua me ntsis, txawm hais tias nws txhua tus nyob ntawm qhov ntau ntawm cov tshuaj.
Kev nqus tshuaj yog nrawm heev. Thaum noj cov tshuaj ua ntej noj mov, nws muaj nyob rau hauv cov ntshav tuaj yeem kuaj pom hauv ib teev thiab ib nrab. Hauv lub cev, cov tshuaj yuav hloov mus rau hauv cov khoom noj ua paug tawm hauv cov zis thiab quav.
Kev taw qhia thiab contraindications
Qhov qhia tau tseem ceeb rau kev siv yog hom ntshav qab zib 2.
Muaj qee qhov xwm txheej thaum koj xav siv cov cuab yeej no:
- nyob rau hauv daim ntawv ntawm monotherapy,
- thaum kho nrog Vildagliptin thiab Metformin, uas yog siv los ua cov tshuaj puv,
- kev siv cov tshuaj nyob rau hauv ua ke nrog cov neeg sawv cev uas txo cov ntshav qab zib thiab muaj sulfanyl urea,
- kev siv cov tshuaj rau hauv ua ke nrog cov tshuaj insulin,
- kev siv cov tshuaj no yog cov tshuaj tseem ceeb hauv kev kho mob ntshav qab zib hom 2, thaum kev noj zaub mov tsis muaj txiaj ntsig ntxiv lawm.
Cov txiaj ntsig ntawm kev noj tshuaj yuav raug ntsuas los ntawm qhov txo qis hauv cov piam thaj hauv cov ntshav.
Thaum yuav siv cov tshuaj yuav tsum tsis txhob:
- intolerance rau cov neeg mob lossis siab rhiab heev rau cov khoom siv ntawm cov khoom siv kho mob,
- ntshav qab zib hom 1
- ua ntej kev ua haujlwm thiab kev tso tawm xoo hluav taws xob, kev ntsuas tshuaj tua hluav taws xob,
- nrog cov teeb meem metabolic, thaum ketones kuaj pom hauv cov ntshav,
- lub siab ua haujlwm tsis zoo thiab tsis ua haujlwm pib tsim,
- mob ntev lossis mob hauv lub plawv lossis ua pa tsis ua haujlwm,
- haus cawv ntau heev,
- cov khoom noj tsis zoo rau lub cev tsawg
- cev xeeb tub thiab lactation.
Ua ntej koj pib noj tshuaj, koj yuav tsum paub tseeb tias tsis muaj cov tshuaj contraindications.
Phiv thiab haus tshaj
Kev siv cov ntsiav tshuaj tuaj yeem ua rau kev txhim kho kev phiv ntawm cov tshuaj, thiab qhov no yuav cuam tshuam cov kev mob ntawm cov kab mob hauv qab no thiab cov tshuab:
- Lub plab zom mov - pib hnov mob, muaj qhov mob nyob rau hauv plab, muaj kua muaj plab tso rau hauv qhov qis ntawm txoj hlab pas, mob rau ntawm daim nyias nyias tuaj yeem ua tau, qhov qab hlau yuav tshwm sim hauv lub qhov ncauj, vitamin B pib muaj kev cuam tshuam tsis zoo.
- Tej leeg hauv siab - mob, kiv taub hau, tshee hnyo.
- Mob siab thiab mob gallstone - kab mob siab.
- Musculoskeletal system - mob hauv pob qij txha, qee zaum hauv cov leeg.
- Cov txheej txheem kev zom zaub mov - nce qib ntawm uric acid thiab ntshav acidity.
- Ua xua - tawm pob rau ntawm daim tawv nqaij thiab khaus, urticaria. Nws tseem ua tau kom tsim muaj cov tsos mob hnyav dua ntawm kev tsis haum ntawm lub cev, uas tau hais tawm hauv angioedema Quincke lossis anaphylactic kev poob siab.
- Muaj qee zaus, cov tsos mob ntawm tus mob ntshav qab zib yog manifested, namely, tshee tshee ntawm sab sauv, "hws txias". Hauv qhov no, kev ua kom tsawg ntawm carbohydrates (tshuaj yej qab zib, confectionery) tau pom zoo.
Yog tias muaj kev phiv los ntawm cov tshuaj pib tsim, ces nws yuav tsum tau txiav nws txoj kev siv thiab nrhiav tswv yim kho mob.
Kev xav ntawm cov kws tshaj lij thiab cov neeg mob
Los ntawm kev tshuaj xyuas ntawm cov kws kho mob thiab cov neeg mob txog Galvus Met, peb tuaj yeem xaus tias cov tshuaj muaj txiaj ntsig hauv kev txo qis ntshav qab zib. Cov kev mob tshwm sim muaj tsawg heev thiab raug tso tseg los ntawm kev txo qis hauv thaj chaw ntawm cov tshuaj.
Cov tshuaj yog zwm rau pab pawg ntawm cov tshuaj IDPP-4, yog sau npe nyob rau hauv Russia ua cov tshuaj rau hom 2 mob ntshav qab zib mellitus. Nws ua hauj lwm zoo thiab nyab xeeb heev, zoo zam txim los ntawm cov ntshav qab zib, tsis ua rau nce phaus ntxiv. Galvus Met raug tso cai siv nrog kev txo qis hauv lub raum, uas yuav tsis ua rau muaj kev kho mob rau cov neeg laus.
Zoo tsim tshuaj. Nws qhia tau zoo heev hauv kev tswj cov qib qab zib.
Yam 2 ntshav qab zib mellitus tau tshawb pom kaum xyoo dhau los. Kuv tau sim siv tshuaj ntau, tab sis lawv tsis txhim kho kuv tus mob ntau. Tom qab ntawd tus kws kho mob qhia Galvus. Kuv tau noj nws ob zaug ib hnub thiab sai li ntawd cov piam thaj tau ua zoo li qub, tab sis cov kev mob tshwm sim ntawm cov tshuaj tshwm sim, uas yog, mob taub hau thiab tawm pob. Tus kws kho mob pom zoo hloov mus rau ib qho tshuaj ntawm 50 mg, qhov no tau pab. Thaum lub sijhawm, tus mob zoo heev, yuav luag tsis nco qab txog tus kabmob.
Maria, 35 xyoo, Noginsk
Ntau tshaj kaum tsib xyoos nrog ntshav qab zib. Tau ntev, kev kho mob tsis nqa cov txiaj ntsig tseem ceeb kom txog thaum tus kws kho mob pom zoo kom yuav Galvus Met. Ib qho cuab yeej zoo, ib koob tshuaj rau ib hnub yog txaus rau qhov qub suab thaj. Thiab txawm hais tias tus nqi ntau dhau, Kuv tsis kam tsis kam siv tshuaj, nws zoo heev.
Nikolay, 61 xyoo, Vorkuta
Cov khoom siv los ntawm Dr. Malysheva txog cov khoom lag luam tuaj yeem pab tshuaj kho ntshav qab zib:
Cov tshuaj yuav tau ntawm txhua lub tsev muag tshuaj. Tus nqi yog li ntawm 1180-1400 rubles., Nyob ntawm thaj av ntawd.