Atomax: cov lus qhia rau kev siv, analogues, nqe, tshuaj xyuas
Atomax hais txog cov tshuaj-statins ntawm lub cim thib peb, uas muaj cov nyhuv lipid-txo qis. Nws yog qhov sib tw xaiv cov khoom thaiv ntawm HMG-CoA reductase, ib qho enzyme uas ua rau muaj kev txwv ntawm cov roj ntsha ua ke thaum ntxov.
Kev siv cov tshuaj muaj feem cuam tshuam rau hauv kev kho mob ntawm hypercholisterinemia thiab nce qib thyroglobulin (TG). Ua tsaug rau Atomax, lipid metabolism tuaj yeem ua tau zoo li qub thiab muaj kev cuam tshuam loj heev ntawm cov roj cholesterol siab tuaj yeem tiv thaiv tau.
Hauv cov ntaub ntawv no koj tuaj yeem nrhiav cov ncauj lus kom ntxaws txog cov tshuaj Atomax, cov lus qhia rau kev siv, tus nqi, kev tshuaj xyuas tus neeg mob thiab cov tshuaj zoo sib xws.
Tso tawm daim ntawv thiab muaj pes tsawg leeg
Atomax yog ib cov tshuaj uas tsom rau HMG-CoA reductase, uas ua rau qeeb hauv cov roj (synthesis) hauv cov qe ntshav qis. Tsis zoo li statins ntawm thawj tiam, Atomax yog tshuaj ntawm cov khoom siv hluavtaws.
Ntawm kev lag luam pharmacological koj tuaj yeem nrhiav cov tshuaj tsim los ntawm lub tuam txhab Indian HeteroDrags Limited thiab cov nroj tsuag hauv tsev ntawm Nizhfarm OJSC, Skopinsky Pharmaceutical Plant LLC.
Atomax muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj dawb uas puag ncig lub cev nrog convex sab. Los ntawm saum toj no lawv yog them nrog ib zaj duab xis daim nyias nyias. Ib pob muaj 30 ntsiav tshuaj.
Cov ntsiav tshuaj suav nrog 10 lossis 20 mg ntawm cov tshuaj nquag - atorvastatin calcium trihydrate.
Ntxiv nrog rau lub ntsiab tivthaiv, txhua ntsiav tshuaj thiab nws lub plhaub muaj qee qhov nqi:
- croscarmellose sodium,
- lim talcum hmoov
- lactose pub dawb
- magnesium stearate,
- pob kws nplej siab
- calcium carbonate
- povidone
- silicon dioxide anhydrous colloidal,
- crospovidone
- triacetin
Ntxiv rau, qee qhov nqi ntawm titanium dioxide nyob hauv qhov npaj.
Tus txheej txheem ntawm kev txiav txim ntawm cov tshuaj nquag
Raws li tau hais ua ntej, lipid-txo cov nyhuv ntawm Atomax tau tiav los ntawm thaiv HMG-CoA reductase. Lub hom phiaj tseem ceeb ntawm cov enzyme no yog los hloov cov methylglutaryl coenzyme A kom mevalonic acid, uas yog qhov ua ntej ntawm cov roj (cholesterol).
Atorvastatin ua rau lub siab ua haujlwm, txo qis ntawm LDL thiab cov roj cholesterol. Nws siv tau zoo los ntawm cov neeg mob kev txom nyem los ntawm homozygous hypercholesterolemia, uas tsis tuaj yeem kho nrog lwm cov tshuaj uas txo cov roj cholesterol. Lub zog ntawm qhov txo qis hauv cov roj (cholesterol) ncaj qha nyob ntawm qhov koob tshuaj ntawm cov khoom tseem ceeb.
Atomax tsis pom zoo kom noj thaum noj mov, zoo li kev noj mov txo tus nqi ntawm kev nqus. Cov tshuaj nquag ua haujlwm yog nqus tau zoo nyob rau hauv cov hnyuv. Cov ntsiab lus siab tshaj plaws ntawm atorvastatin raug pom 2 teev tom qab thov.
Nyob hauv kev cuam tshuam ntawm cov enzymes tshwj xeeb CY thiab CYP3A4, cov metabolism tshwm sim hauv lub siab, vim tias cov tshuaj parahydroxylated tau tsim. Tom qab ntawd cov metabolites raug tshem tawm ntawm lub cev nrog rau cov kua tsib.
Kev taw qhia thiab contraindications rau kev siv tshuaj
Atomax yog siv los txo cov roj (cholesterol). Tus kws kho mob sau ntawv muab tshuaj rau hauv cov tshuaj nrog kev noj zaub mov kom zoo rau kev kuaj mob raws li qhov tseem ceeb tshaj plaws, tsev neeg mob heterozygous thiab tsis nyob hauv tsev.
Kev siv cov ntsiav tshuaj kuj tseem cuam tshuam rau kev paub ntau ntxiv ntawm thyroglobulin (TG), thaum kev noj zaub mov noj tsis nqa cov txiaj ntsig uas xav tau.
Atorvastatin txo cov roj cholesterol hauv cov neeg mob homozygous tsev neeg hypercholesterolemia, thaum tsis yog kev kho tshuaj thiab kev noj haus tsis ua rau lub cev lipid metabolism.
Atomax raug txwv rau qee pawg ntawm cov neeg mob. Cov kev qhia muaj ib daim ntawv teev cov kev tsis sib haum xeeb rau kev siv tshuaj:
- Cov menyuam yaus thiab hnub nyoog qis dua 18 xyoo.
- Lub sij hawm ntawm kev xeeb tub thiab pub niam mis.
- Kab mob siab Hepatic tsis paub meej keeb kwm.
- Kev tsis haum xeeb rau cov khoom siv hauv cov khoom.
Cov tshuaj yog sau ntawv nrog kev ceev faj thaum ua rau lub zog ntawm txoj hlab ntshav siab, qhov tsis txaus ntawm electrolytes, kev ua haujlwm tsis zoo ntawm cov endocrine system, daim siab mob pathologies, mob ntev cawv thiab mob vwm, uas tsis tuaj yeem tswj tau.
Cov lus qhia rau kev siv tshuaj
Lub hauv paus tseem ceeb hauv kev kho Atomax yog kev soj ntsuam ntawm kev noj zaub mov tshwj xeeb. Khoom noj khoom haus yog ua rau txo qis cov khoom noj uas muaj cov roj cholesterol siab. Yog li, cov zaub mov tsis suav nrog kev noj viscera (ob lub raum, paj hlwb), qe qe, butter, nqaij npuas muaj roj, thiab lwm yam.
Kev noj tshuaj atorvastatin txawv ntawm 10 txog 80 mg. Raws li txoj cai, tus kws kho mob koom nrog sau ntawv tso cai muab thawj koob tshuaj 10 mg rau ib hnub. Ntau yam ua rau muaj ntau npaum li cas ntawm cov tshuaj, xws li cov qib ntawm LDL thiab cov roj (cholesterol) tag nrho, cov hom phiaj ntawm kev kho thiab nws cov hauj lwm zoo.
Ua kom ntau dua qhov ntau npaum li cas tuaj yeem nqa tawm tom qab 14-21 hnub. Hauv qhov no, kev xav txog cov lipids hauv cov ntshav ntshav yog yuav tsum ua.
Tom qab 14 hnub ntawm kev kho mob, qhov kev txo qis hauv cov qib roj yog pom, thiab tom qab 28 hnub qhov siab tshaj plaws ua tau tiav. Nrog lub sijhawm ntev los kho, lipid metabolism rov zoo li qub.
Cov ntim ntawm cov tshuaj yuav tsum muab cia rau hauv qhov chaw tiv thaiv los ntawm ncaj qha tshav ntuj kom deb ntawm cov menyuam yaus. Qhov ntsuas kub ntawm qhov tso cia nws txawv ntawm 5 txog 20 degrees Celsius.
Txee lub neej yog 2 xyoos, tom qab lub sijhawm no cov tshuaj txwv tsis pub noj.
Tej zaum ua rau mob thiab dhau cai
Kev tswj hwm tus kheej ntawm cov tshuaj rau txoj kev kho cov tshuaj yog nruj me ntsis txwv tsis pub.
Qee zaum, ib qho tshuaj yuav ua rau muaj kev phiv tshuaj nyob hauv tus neeg mob.
Ua ntej siv Atomax, koj yuav tsum sab laj nrog koj tus kws kho mob.
Cov ntaub ntawv qhia hais tias qhov tshwm sim muaj feem ntawm cov kev mob tshwm sim:
- Kev tsis sib haum ntawm lub hauv nruab nrab cov hlab ntsha: asthenic syndrome, pw tsis tsaug zog lossis tsaug zog, npau suav phem, qaug zog, dias taub hau, mob taub hau, mob siab, tinnitus, teeb meem kev pab, paresthesia, peripheral neuropathy, saj tsis zoo, qhov ncauj qhuav.
- Cov tshuaj tiv thaiv cuam tshuam nrog cov kabmob ntsig txog qhov tsis hnov tsw: kev txhim kho ntawm lag ntseg, lub qhov muag qhuav.
- Cov teeb meem ntawm cov hlab plawv thiab cov hlab ntsha ua haujlwm: phlebitis, anemia, angina pectoris, vasodilation, orthostatic hypotension, thrombocytopenia, lub plawv dhia, nce siab tsis txaus.
- Kev ua haujlwm ntawm lub plab zom mov thiab lub plab hlaub: kev cem quav, raws plab, xeev siab thiab ntuav, mob plab, mob plab hnyuv tws, ua rau lub plab, ua rau lub siab kub, ua kom muaj roj ntau dua, muaj tus mob ua kom huam sai.
- Kev tawm tsam ntawm daim tawv nqaij: khaus, tawm pob, ua viav vias, o ntawm lub ntsej muag, kev zoo nkauj.
- Qhov teeb meem ntawm cov leeg mus ntawm lub cev: mob leeg ntawm cov leeg qis, mob hauv kev sib cog lus ntawm pob qij txha thiab sab nraub qaum, mob mob leeg mob, mob rwj mob, mob caj dab, mob exacerbation ntawm gout.
- Malfunctioning tso zis: tso zis qeeb, cystitis.
- Deterioration ntawm kev kuaj pom: hematuria (ntshav hauv cov zis), albuminuria (protein hauv cov zis).
- Lwm yam kev cuam tshuam: hyperthermia, txo qis kev sib deev muaj zog, ua haujlwm erectile kawg, alopecia, tawm hws ntau dhau, seborrhea, stomatitis, cov pos hniav los ntshav, qhov quav, lub paum thiab lub qhov ntswg.
Kev noj tshuaj ntau dua ntawm atorvastatin ua rau muaj kev pheej hmoo mob raum, nrog rau myopathy (kab mob neuromuscular) thiab rhabdomyolysis (mob hnyav ntawm myopathy).
Txog hnub, tsis muaj ib yam tshuaj tshwj xeeb rau cov tshuaj no.
Yog tias cov cim qhia txog kev noj ntau dhau tshwm sim, lawv yuav tsum tau muab tshem tawm. Hauv qhov no, hemodialysis yog qhov ua tsis tau zoo.
Kev cuam tshuam nrog lwm yam tshuaj
Cov tshuaj yeeb tshuaj nquag muaj peev xwm hloov tawm ntawm lawv tus kheej sib txawv, vim qhov txiaj ntsig los ntawm kev kho tshuaj ntawm Atomax tuaj yeem ntxiv dag zog lossis qaug zog.
Qhov ua tau ntawm kev cuam tshuam ntawm cov tshuaj ntawm cov tshuaj ntau yam yuav tsum tau hais tias tus neeg mob yuav tsum qhia tus kws kho mob uas koom nrog kev noj tshuaj uas cuam tshuam rau Atomax cov haujlwm.
Hauv cov lus qhia rau kev siv tshuaj hypolipidemic, muaj cov ntaub ntawv tiav txog kev cuam tshuam nrog lwm cov tshuaj.
- Ua ke nrog kev kho mob nrog cyclosporine, erythromycin, fibrates thiab antifungal agents (pawg azoles) ua rau muaj kev pheej hmoo ntawm cov kab mob neuromuscular - myopathy.
- Hauv kev tshawb nrhiav, kev tswj hwm tib lub sijhawm ntawm Antipyrine tsis ua rau muaj kev hloov pauv tseem ceeb hauv cov tshuaj pharmacokinetics. Yog li ntawd, kev sib txuas ntawm ob qho tshuaj tau tso cai.
- Kev siv txig txuas ntawm kev ncua kev txiav txim siab uas muaj magnesium hydroxide lossis aluminium hydroxide ua rau txo qis hauv cov ntsiab lus ntawm atorvastatin hauv ntshav.
- Kev sib xyaw ntawm Atomax nrog cov tshuaj txwv tswj uas muaj tinylestradiol thiab norethindrone tsub kom ntau dua AUC ntawm cov feem.
- Kev siv tib lub sij hawm ntawm colestipol txo cov theem ntawm atorvastatin. Qhov no nyeg txhim kho cov lipid-txo cov nyhuv.
- Atomax tuaj yeem nce digoxin hauv cov hlab ntshav. Yog tias tsim nyog, kev kho mob nrog cov tshuaj no yuav tsum ua raws li kev saib xyuas mob nkeeg.
- Cov thawj coj loj ntawm Azithromycin tsis cuam tshuam rau cov ntsiab lus ntawm cov kev nquag ntawm Atomax hauv cov ntshav ntshav.
- Kev siv erythromycin thiab clarithromycin ua rau nce qib hauv atorvastatin hauv cov ntshav.
- Thaum cov chaw sim tshuaj, tsis pom muaj tshuaj lom ntawm Atomax thiab Cimetidine, Warfarin.
- Kev nce qib ntawm cov tshuaj nquag tau pom nrog kev sib txuam nrog cov tshuaj nrog cov tshuaj tiv thaiv protease.
- Yog tias tsim nyog, tus kws kho mob tso cai rau koj los sib xyaw Atomax nrog cov tshuaj, uas suav nrog Amplodipine.
- Cov kev tshawb fawb txog yuav ua li cas cov tshuaj cuam tshuam nrog cov tshuaj antihypertensive tsis tau ua.
Nrog kev sib xyaw ntawm Atomax nrog estrogens, tsis muaj qhov tshwm sim tsis zoo tshwm sim.
Nqe, tshuaj xyuas thiab analogues
Muaj cov xov xwm me me ntawm qhov ua tau zoo ntawm kev siv Atomax hauv Is Taws Nem. Qhov tseeb yog tias tam sim no, IV tiam statins raug siv rau hauv kev kho mob. Cov tshuaj no muaj qhov nruab nrab noj thiab tsis ua rau muaj kev mob tshwm sim ntau.
Atomax nyuaj txaus los yuav hauv khw muag tshuaj ntawm lub teb chaws vim qhov tseeb tias tam sim no nws yuav luag tsis siv. Qhov nruab nrab, tus nqi ntawm ib pob (30 ntsiav tshuaj ntawm 10 mg) thaj tsam ntawm 385 txog 420 rubles. Yog tias tsim nyog, cov tshuaj yuav tuaj yeem txiav txim online ntawm cov ntaub ntawv lub vev xaib ntawm cov tuam ntxhab.
Muaj ob peb tshuaj xyuas ntawm lipid-txo tus neeg sawv cev ntawm cov ncauj lus thematic. Rau feem ntau, lawv tab tom tham txog qhov tshwm sim ntawm kev phiv tshuaj thaum noj cov tshuaj. Txawm li cas los xij, nyias muaj nyias kev xav.
Vim muaj ntau yam contraindications thiab kev tsis zoo, qee zaum tus kws kho mob sau ib qho lus sau (cov tshuaj uas muaj tib yam tshuaj lom) lossis cov tshuaj analogue (muaj cov sib txawv ntawm cov tshuaj sib txawv, tab sis tsim cov tshuaj zoo sib xws).
Cov lus ua ntxiv ntawm Atomax tuaj yeem muas tau ntawm Lavxias kev ua lag luam tshuaj:
- Atovastatin (No. 30 ntawm 10 mg - 125 rubles),
- Atorvastatin-Teva (No. 30 rau 10 mg - 105 rubles),
- Atoris (No. 30 rau 10 mg - 330 rubles),
- Liprimar (No. 10 ntawm 10 mg - 198 rubles),
- Novostat (No. 30 rau 10 mg - 310 rubles),
- Tulip (No. 30 rau 10 mg - 235 rubles),
- Torvacard (No. 30 rau 10 mg - 270 rubles).
Ntawm cov tshuaj tiv thaiv zoo ntawm Atomax, nws yog qhov tsim nyog kom paub qhov txawv ntawm cov tshuaj:
- Akorta (No. 30 rau 10 mg - 510 rubles),
- Krestor (naj npawb 7 rau 10 mg - 670 rubles),
- Mertenil (No. 30 rau 10 mg - 540 rubles),
- Rosuvastatin (Zaj 28 ntawm 10 mg - 405 rubles),
- Simvastatin (No. 30 ntawm 10 mg - 155 rubles).
Tau ua tib zoo kawm cov tshuaj Atomax, cov lus qhia rau kev siv, nqi, analogues thiab cov tswv yim ntawm cov neeg siv khoom, tus neeg mob, ua ke nrog tus kws tshaj lij uas tuaj koom, yuav muaj peev xwm soberly ntsuas qhov xav tau rau kev noj tshuaj.
Cov ntaub ntawv hais txog statins yog muab hauv video hauv tsab xov xwm no.
Kev Sau ua ke, daim foos tso tawm
Cov tshuaj muaj zog ntawm Atomax yog atorvastatinCov. Kev ua haujlwm pabcuam yog ua los ntawm calcium carbonate, mis nyuj qab zib, cellulose, croscarmellose sodium, povidone K-30, magnesium stearate, hypromellose, talc, titanium dioxide, triacetin.
Atomax - pleev xim dawb ntsiav tshuaj nrog qhov thais kom yooj yim rau kev faib khoom. Ob ntau yam ntawm cov tshuaj uas tsim tawm nrog cov lus qhia tseem ceeb ntawm 10 lossis 20 mg.
Pharmacological kev txiav txim
Lub hauv paus ntsiab lus ntawm atorvastatin yog raws li nws lub peev xwm los thaiv cov haujlwm ntawm HMG-CoA reductase. Qhov enzyme no yog lub luag haujlwm rau kev pib ua ntej ib theem ntawm cov roj (synthesis) roj. Ib zaug hauv lub cev, Atomax inhibits kev sib txuas ntawm sterol, ua rau txo qis hauv nws qib. Txhawm rau kom them taus cov roj (cholesterol) tsis txaus, qhov tawg ntawm "cov teeb meem" uas tsis muaj roj lipoproteins tsawg (LDL), uas muaj cov tshuaj tsim nyog, ua haujlwm. Nyob rau tib lub sijhawm, lub cev txhim kho kev sib txuas ntawm "zoo" high-density lipoproteins (HDL), uas yog lub luag haujlwm xa cov sterol los ntawm cov ntaub so ntswg.
Cov kev hloov pauv hauv kev xav ntawm cov roj (cholesterol), lipoproteins tuaj yeem tiv thaiv kev txhim kho atherosclerosis, nrog rau cov kab mob ntsig txog - mob stroke, lub plawv nres, necrosis ntawm qhov kawg.
Qhov siab tshaj plaws ntawm atorvastatin hauv cov ntshav tshwm sim hauv 1-2 teev tom qab kev coj noj coj ua. Kev thaiv cov peev xim nyob rau 20-30 teev. Cov tshuaj tau tawm ntawm daim siab, cov tshuaj me me nrog tso zis. Qhov no tso cai Atomax tau raug tshuaj rau cov teeb meem lub raum, tab sis yuav tsum tau siv kev xyuam xim rau cov neeg mob uas lub siab tsis ua haujlwm.
Cov Tshuaj Hauv Tshuaj
Ib cov tshuaj uas muaj cov nyhuv hypolipidemic qhia tau zoo. Lub tshuab kev ua ntawm kev ua raws nws xaiv muaj peev xwm sib tw muaj peev xwm inhibit HMG-CoA reductase - lub enzyme lub ntsiab hauv cov txheej txheem hloov dua siab tshiab methylglutaryl coenzyme A hauv mevalonic acidmuaj feem xyuam rau cov ua ntej ntawm cov tshuaj steroids, suav nrog rojCov. TG thiab roj hauv lub siab yog suav nrog VLDL, tom qab ntawd lawv nkag mus rau hauv cov hlab ntshav thiab thauj mus rau hauv lub cev nqaij. Ntxiv mus, VLDL yog tsim los ntawm VLDL, uas, thaum sib cuam tshuam nrog LDL receptors, yog catabolized.
Phiaj hloov khoom nruab nrog atorvastatin yog lub siab thiab ncaj qha rau cov txheej txheem synthesis roj thiab kev tshem tawm ntawm LDL. Atomax txo synthesis roj thiab txo qis ntawm LDL hais me me. Cov tshuaj no zoo rau cov neeg mob homozygous hypercholesterolemiatsis kho los ntawm lwm cov tshuaj lipid. Cov koob tshuaj ntawm cov tshuaj yog xaiv ib tus zuj zus coj mus rau hauv tus txheej txheem kho qhov ua tau zoo, txij li qhov zoo li qub tsis kam roj correlates yig nrog cov koob tshuaj ntawm cov tshuaj.
Cov Tshuaj Pharmacokinetics
Atomax yog nqus tau zoo nyob rau hauv cov hnyuv, kev noj zaub mov kom tsawg dua qhov feem pua ntawm kev nqus. Cmax - kwv yees li 2 teev, kev noj yuav muaj nyob rau theem 30%, uas yog vim yog lub cev presystemic metabolism ntawm cov tshuaj thaum thawj "tawm thawj" hauv lub plab thiab lub siab.
Metabolized los ntawm cov enzymes CYP3A4 5 thiab CY hauv daim siab ua haujlwm parahydroxylated metabolitesnrog kev ua haujlwm pharmacological siab. Nws yog tawm hauv cov kab tsib tom qab cov kab mob hepatic. T1 / 2 txog 15 teev.
Kev ntsuas rau siv
- Txhawm rau kom txo tag nrho roj (hauv kev sib xyaw nrog zaub mov noj) hauv cov neeg mob nrog thawj hypercholesterolemiauas tsis yog tsev neeg thiab tsev neeg heterozygous hypercholesterolemia,
- Ua kom cov ntshav TG ntau ntxiv nyob rau hauv cov neeg mob uas kev kho kev noj haus tsis zoo,
- Txhawm rau kom txo qis tag nrho roj nyob rau hauv cov neeg mob nrog homozygous tsev neeg hypercholesterolemia, nrog qhov tsis muaj txiaj ntsig ntawm kev noj zaub mov noj thiab txoj kev kho mob tsis yog-pharmacological.
Cov Yuav Tsum Muaj
Siab rhiab heev rau Atomax, kab mob siab uas tsis paub keeb kwm, hnub nyoog qis dua 18 xyoo, cev xeeb tubkev pub mis. Noj nrog ceev faj nyob rau hauv cov neeg mob uas muaj mob electrolyte tsis txaus, arterial hypotension, endocrine cuam tshuam, kab mob siab, nrog mob ntev quav cawvtswj tsis tau qaug dab peg.
Sab sij huam
Cov tsos mob Asthenicqhov ncauj qhuav tsaug zoglossis insomnia, kiv taub hau, amnesia, mob taub haunpau suav phem paresthesiaperipheral neuropathy, txoj kev xav lability, kev nyuaj siab, kev ua kom muaj kev cuam tshuam nrog kev cuam tshuam, haus txias, saj tsis meej, lag ntseg, qhuav tes taw, mob hauv siab, mob hauv siab, orthostatic hypotension, anemia, phlebitis, vasodilation, thrombocytopeniataub ntswg zawv plab/cem quav, mob ntsws, arrhythmiacov pos hniav los ntshav hepatic colic, flatulencekev hlwv, xeev siab, kub siab, pancreatitismob plab ntuav mob plabqhov quav los ntshav mob mob vwmtxhais ceg mob, mob nraub qaum, sib koom tes sib cog lus, rhabdomyolysis, mob caj dab, albuminuriatxo qis libido cystitis, hws, seborrhea, hematuriapojniam los ntshav impotencekhaus tawv nqaij, hnyav tuaj, epididymitiskev txom nyem mob gout, eczema, alopecia, o ntawm lub ntsej muagkev tso zis cia photosensitizationnce lub cev kub.
Cov lus qhia Atomax rau siv (Txujci thiab ntau npaum li cas)
Atomax kho yuav tsum tau nqa tawm ntawm keeb kwm yav dhau lipid-txo cov zaub mov nojtxuas ntxiv thoob plaws hauv lub sijhawm kho. Kev noj tshuaj ntau npaum li cas los ntawm 10-80 mg. Qhov nruab nrab, qhov pib koob tshuaj yog 10 mg thiab tau noj 1 zaug nyob rau ib hnub, tsis hais txog kev noj zaub mov. Qhov ntau npaum ntawm cov tshuaj xaiv tau xaiv rau tus neeg mob los ntawm qib roj/ LDL, cov hom phiaj kho thiab kho kom zoo dua. Thaum pib ntawm kev kho mob thiab nrog kev nce hauv ntau npaum li cas ntawm Atomax, nws yog ib qho tsim nyog los tswj cov ntsiab lus ntawm lipids hauv cov ntshav ntshav txhua 2-3 lub lis piam thiab kho qhov tshuaj.
Cov txiaj ntsig kho qhov tshwm sim nws tus kheej tsis dhau 2 lub lis piam, thiab qhov siab tshaj plaws - tom qab 4 lub lis piam, uas nrog kev siv lub sijhawm ntev ntawm cov tshuaj muaj txiaj ntsig zoo.
Atomax: cim qhia rau siv
Raws li cov lus qhia, Atomax yog kho rau cov neeg mob nrog:
- thawj hypercholesterolemia, heterozygous tsev neeg, tsis-tsev neeg hypercholesterolemia,
- sib xyaw hyperlipidemia,
- hypertriglyceridemia,
- dbetalipoproteinemia.
Atomax muaj kev tiv thaiv zoo rau kev tiv thaiv cov kev mob hnyav ntawm atherosclerosis rau cov neeg mob uas muaj cov tsos mob ntawm txoj hlab ntshav ntawm lub cev. Nws yog tshuaj rau tib neeg muaj kev pheej hmoo ntawm kev mob plawv mob ntshav siab raws li ob lossis ntau yam: kev haus luam yeeb, rog dhau, hnub nyoog, kev noj zaub mov tsis zoo, kev ua neej tsis muaj sia.
Txoj kev ntawm daim ntawv thov, ntau npaum li cas
Atomax yog tshuaj tsuas yog ntxiv rau kev noj haus, yog tias nws tsis muaj txiaj ntsig. Nws yuav tsum raug pom thaum tag nrho lub sijhawm ntawm kev kho mob.
Thaum noj cov tshuaj statin, koj yuav tsum ua raws li cov cai yooj yim. Haus ib ntsiav tshuaj Atomax tib lub sijhawm, 1 zaug / hnub, muaj dej txaus. Nws tsis tuaj yeem raug zom, txhuam.
Kev kho mob pib nrog kev noj tshuaj tsawg kawg nkaus. Kuv tsom mus rau kev hloov pauv hauv cov roj cholesterol, lipoproteins, tus kws kho mob tuaj yeem hloov kho qhov tshuaj tom qab 2-4 lub lis piam. Qhov ntau kawg pub rau tsuas pub yog 80 mg. Yog tias qhov tshuaj ntau npaum li no ntawm atorvastatin ua tsis tau zoo, Atomax hloov nrog lub hnub nyoog muaj zog ntau dua los yog lwm cov tshuaj txo cov roj (cholesterol) tsawg dua tau suav nrog kev kho mob.
Rau feem ntau cov neeg mob uas muaj thawj hypercholesterolemia, nrog rau kev sib xyaw hyperlipidemia, 10 mg ntawm cov tshuaj yog txaus.
Cov neeg muaj homozygous tsev neeg hypercholesterolemia noj cov tshuaj ntawm 80 mg 3 zaug / hnub (20 thaum sawv ntxov, 20 nyob rau yav tav su, 40 thaum yav tsaus ntuj). Raws li txoj cai, qhov no txaus kom txo qis roj los ntawm 18-45%.
Kev ceev faj yuav tsum tau siv thaum tshuaj Atomax rau cov neeg mob uas:
- haus cawv ntau
- muaj kab mob siab
- txom nyem los ntawm cov khoom noj hauv lub cev, cov teeb meem hormonal tsis txaus, qaug dab peg, hypotension, cov leeg pob txha pathologies,
- nrog kev phais sab nrauv.
Atomax: cov lus qhia rau kev siv, nqi, xyuas, analogues
Atomax yog cov tshuaj lipid-txo qis rau kev kho cov pab pawg kho mob HMG-CoA reductase inhibitors.
Nws yog siv los txo qhov kev kub siab ntawm apolipoprotein B, tag nrho cov roj cholesterol, triglycerides, LDL thiab VLDL hauv cov neeg mob uas tau los ntawm thawj hypercholesterolemia, tsev neeg thiab tsis yog tsev neeg heterozygous hypercholesterolemia thiab cov tshuaj sib xyaw ua ke ntawm hyperlipidemia hauv cov neeg mob dysbetalipoproteinemia nrog triple ntshav ntshav theem 3 nyhuv ntawm kev noj haus. Nws yog contraindicated nyob rau hauv cov ntaub ntawv ntawm siab kev ua si ntawm daim siab enzymes, hypersensitivity, lactation, active daim siab pathologies, cev xeeb tub thiab hauv kev xyaum tu menyuam yaus.
Kev piav qhia thiab muaj pes tsawg leeg
Atomax yog biconvex round-puab ntsiav tshuaj coated nrog dawb zaj duab xis txheej. Kev nruj ntawm npoo av tau raug tso cai.
1 ntsiav tshuaj muaj 10 mg lossis 20 mg ntawm atorvastatin.
- titanium dioxide
- crospovidone
- magnesium stearate,
- povidone
- croscarmellose sodium,
- talcum hmoov
- colloidal anhydrous silica,
- lactose
- hmoov txhuv nplej siab
- primellose 15 CPS.
Rau cov laus
Atomax yog tsim rau cov neeg mob cov neeg laus uas muaj tej yam mob xws li:
- txo qis hauv cov roj (cholesterol) tag nrho, triglycerides, apolipoprotein B, LDL thiab VLDL hauv cov neeg mob thawj cov neeg mob hypercholesterolemia, tsis muaj tsev neeg thiab tsev neeg heterozygous hypercholesterolemia thiab sib xyaw hyperlipidemia,
- kev kho mob ntawm cov neeg mob kev txom nyem los ntawm cov ntshav nce qib triglycerides thiab dysbetalipoproteinemia (nyob rau hauv qhov tsis muaj cov nyhuv raug ntawm kev noj zaub mov noj).
Atomax yog contraindicated rau hauv cov menyuam yaus thiab cov hluas hnub nyoog qis dua 18 xyoo.
Kev cuam tshuam nrog lwm yam tshuaj
Txoj kev pheej hmoo ntawm myopathy thaum kho nrog lwm cov tshuaj ntawm cov chav kawm no nce nrog kev siv cyclosporine, erythromycin, fibrates, antifungals.
Nrog kev siv ua ke ntawm atorvastatin thiab erythromycin lossis clarithromycin, qhov nce ntawm cov ntsiab lus ntawm atorvastatin hauv cov ntshav cov ntshav tau sau tseg.
Kev siv ua ke ntawm atorvastatin nrog cov tshuaj tiv thaiv protease inhibitors tau los ntawm kev nce ntxiv ntawm cov qib atorvastatin.
Cov lus qhia tshwj xeeb
Ua ntej pib txoj kev kho mob nrog Atomax, tus neeg mob yuav tsum sau ntawv noj tshuaj kom tsis txhob mob hypocholesterol, uas nws yuav tsum tau ua raws thaum kho.
Kev siv HMG-CoA reductase inhibitors kom txo cov ntshav lipids tuaj yeem ua rau cov kev hloov pauv hauv biochemical hloov uas muaj kev cuam tshuam daim siab ua haujlwm.
Qhov cuam tshuam tsis zoo rau kev muaj peev xwm tsav tsheb tsis tau tshaj tawm, txawm li cas los xij, muab qhov xwm txheej ntawm cov kev mob tshwm sim, kev ceev faj yuav tsum tau siv thaum ua cov haujlwm uas muaj feem phom sij.
Cia rau cov neeg mob
Atomax yuav tsum muab cia kom ncav tsis cuag ntawm cov menyuam yaus, hauv qhov chaw qhuav, tiv thaiv los ntawm tshav ntuj. Cia kub - tsis ntau tshaj 25 ° °.
Txee lub neej yog 2 xyoos.
Kev siv cov tshuaj Atomax yeej tsis muab qhov kev kho kom zoo ib yam rau txhua tus neeg mob. Hauv no hais txog, hauv khw muag tshuaj muaj ntau yam tshuaj zoo sib xws.
Mertenil
Mertenil yog qhov xaiv thiab kev sib tw inhibitor ntawm HMG-CoA reductase. Cov tshuaj ua cov suab nrov lipid-txo cov nyhuv.
Mertenil yog tshuaj rau hypertriglyceridemia, hypercholesterolemia, ua ke ntawm dyslipidemic mob, zoo li rau kev tiv thaiv thawj ntawm cov hlab plawv pathologies. Cov tshuaj muaj ntau qhov tsis sib haum thiab kev txwv tsis pub siv.
Ua ntej pib kev kho mob, nws raug nquahu kom nrog lub tsev kho mob thiab sab laj nrog kws kho mob.
Atotex
Atotex yog lipid-txo cov tshuaj uas muaj atorvastatin ua cov tshuaj tiv thaiv. Nws yog siv rau cov ntsuas zoo tib yam li cov tshuaj Atomax. Atotex yog txwv tsis pub siv rau lub sijhawm cev xeeb tub, pub niam mis, tsis saib xyuas tsis pub muaj menyuam los ntawm cov neeg mob hnub nyoog yug menyuam, kev mob siab rau lub siab, tsis nco qab thiab muaj hnub nyoog qis dua 18 xyoo.
Tulip
Cov tshuaj Tulip belongs rau pharmacological series ntawm kev xaiv (xaiv) kev sib tw inhibitors ntawm HMG-CoA reductase.
Nws yog siv los kho tus thawj hypercholesterolemia, ua ke ua ke ntawm hyperlipidemia, thiab kuj yog ib qho ntxiv rau kev noj haus kom tshem tawm homozygous thiab heterozygous tsev neeg hypercholesterolemia.
Nws yog txwv tsis pub rau kev ua haujlwm tsis zoo, ua lub siab ua rau lub siab, ua haujlwm lub siab tsis ua haujlwm, muaj menyuam hauv plab, pub niam mis, ua haujlwm ntau ntxiv ntawm daim siab daim siab uas tsis paub txog keeb kwm, tsis quav ntsej txog kev siv tshuaj kom muaj txiaj ntsig txaus los ntawm cov neeg mob hnub nyoog deev thiab kev xyaum yug menyuam.
Livazo
Cov nquag ua haujlwm yog calcium pitavastatin. Cov tshuaj tiv thaiv hypolipidemic.
Cov ntsiab lus rau kev siv ntawm Livazo suav nrog cov kab ke hauv qab no: ib qho kev txo qis hauv LDL thiab VLDL, triglycerides, tag nrho cov roj (cholesterol) thiab apolipoprotein B tawm tsam keeb kwm ntawm tsev neeg heterozygous dib thawj hypercholesterolemia thiab lub cev sib xyaw ntawm dyslipidemia. Cov tshuaj tiv thaiv yog cov xwm txheej zoo ib yam li rau cov tshuaj ua dhau los.
Vasilip
Ib qho lipid-txo cov tshuaj hauv daim ntawv ntawm cov ntsiav tshuaj muaj simvastatin yog ib yam tshuaj muaj sia.
Nws yog qhov khoom noj ntxiv rau txoj kev noj zaub mov tshwj xeeb rau thawj tsev neeg lossis tsev neeg (homozygous) hypercholesterolemia, hypertriglyceridemia, sib xyaw dyslipidemia, thiab tseem ua rau muaj kev cuam tshuam txog kev kho plawv ntawm cov ntshav hauv cov neeg mob nrog cov tsis tseem ceeb. Vasilip raug txwv nyob rau hauv daim siab pathologies (suav nrog kev hloov siab ntau ntawm kev hloov tsheb), lactation, cev xeeb tub, thev tsis tau, thiab rau cov menyuam yaus hnub nyoog qis dua 18 xyoo.
Lovagexal
Lovagexal ntsiav tshuaj muaj lub zog ua haujlwm ntawm lovastatin. Cov tshuaj yeeb yaj kiab tsuas yog siv los yog tsim nyog txhawm rau txo qis ntawm LDL, triglycerides, VLDL thiab tag nrho cov roj (cholesterol) hauv cov ntshav nrog hypertriglyceridemia thiab thawj qhov sib xyaw ua ke thiab hypercholesterolemia.
Cov tshuaj Lovagexal yog contraindicated rau kev siv hauv cov menyuam yaus hnub nyoog qis dua 12 xyoos, hauv cov neeg mob uas mob raum lossis mob rau lub cev tsis muaj peev xwm, nrog rau kev mob hnyav ntawm lub cev.
Thaum lub sijhawm cev xeeb tub thiab pub niam mis, cov tshuaj tsis raug txwv.
Tus nqi ntawm Atomax yog nyob nruab nrab ntawm 81 txog 390 rubles.
Qhov ua tau zoo ntawm cov tshuaj Atomax tawm tsam cov cholesterol
Cov neeg mob nug li cas kom noj Atomax rau cov roj (cholesterol)? Txhawm rau muaj ib lub tswv yim hais txog cov tshuaj, koj yuav tsum paub nws lub hom phiaj, hom, nyhuv.
Yog tias ib tus neeg muaj qhov nce lossis qis dua hauv ib yam khoom hauv lub cev, qhov no tuaj yeem ua rau lub hauv paus tsis ua haujlwm hauv qee cov kab ke. Txhawm rau kom rov tshuav nyiaj, siv yeeb tshuaj, ib qho ntawm cov tshuaj no.
Nrog cov roj cholesterol, Atomax muab kev kho mob zoo tshaj plaws.
Yuav ua li cas Siv Atomax nrog cov roj (cholesterol)?
Cov tshuaj yog nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj. Lawv sab yog convex, nplaim yog ntxhib. Ntawm ib sab muaj kev pheej hmoo. Lawv muaj lub plhaub soluble, muaj qhov txawv ntawm cov xim dawb. Cov ntsiav tshuaj tau ntim rau hauv cov hlwv, uas tau muab ntim rau hauv lub thawv ntawv tuab tuab.
- cov tshuaj nquag (cov khoom tseem ceeb), uas yog atorvastatin,
- pob kws nplej siab
- calcium carbonate
- lactose
- povidone
- croscarmellose sodium,
- silicon
- anhydrous colloidal dioxide,
- crospovidone.
Lub plhaub ntawm cov ntsiav tshuaj ua dab tsi? Los ntawm triacetin, huv talc, primmeloza, titanium dioxide.
Yuav ua li cas haus Atomax, cov lus qhia rau kev siv ntawm uas muaj hauv ntim, txhua tus yuav tsum paub. Qhov no yog qhov lipid-txo cov tshuaj, qhov kev txiav txim ntawm kev tsom mus rau txo qis roj, uas cuam tshuam tsis zoo rau tib neeg lub cev.
Tus neeg pab pawg ntawm cov statins. Tsis tas li, cov tshuaj yeeb yaj kiab yog cov sib tw xaiv tau tshuaj tiv thaiv ntawm HMG-CoA reductase. Nws tseem tseem npaj rau lwm lub luag haujlwm: txo qis ntshav lipoproteins ntshav.
Atomax muaj txiaj ntsig muaj txiaj ntsig ntawm tsawg lipoproteins uas tsis muaj roj nyob rau ntawm daim siab ua haujlwm.
Raws li kev kho mob, kev tiv thaiv pheej ua ntu zus nyob hauv qhov kev ua haujlwm ntawm LDL receptors tau pom. Nws tsim nyog sau cia kom txo kev pheej hmoo ntawm kev tsim kho thiab tau txais kev cuam tshuam ntawm ischemia.
Cov tshuaj tsis muaj qhov cuam tshuam zoo rau lub cev.
Thaum twg thiaj li tos qhov txiaj ntsig? Txhawm rau kom pom qhov hloov pauv zoo, koj yuav tsum tau noj tshuaj tsawg kawg 2 lub lis piam. Cov tshuaj yuav tsum tau siv nyob ib hlis pib ntawm kev pib kho. Tom qab qhov kev kawm tiav, cov nyhuv yuav pom ntev ntev.
Kev ntsuas rau siv. Atomax yog hauv cov teeb meem xws li:
- Cov roj (cholesterol) siab.
- Muaj zog LDL-C kom pom tseeb.
- Kev nce hauv thyroglobulin thiab apolipropylene B.
- Yog qib theem ntawm cov ntshav TG nce ntxiv.
- Nyob rau hauv rooj plaub thaum thaum dysbetalipoproteinemia tsim.
Atomax yog qhov tsis muaj txiaj ntsig yog tias tus neeg mob tsis ua raws li kev noj zaub mov tshwj xeeb uas kws kho mob tau sau tseg. Cov tshuaj no yog cov pabcuam thiab ua nrog rau cov khoom noj tshwj xeeb.
Yuav ua li cas noj thiab dab tsi yog qhov ntau npaum ntawm cov tshuaj? Ua ntej pib txoj kev kho mob, tus neeg mob yuav tsum hloov mus rau kev noj zaub mov lipid-tshwj xeeb. Cov kws kho mob pom zoo muab cov koob tshuaj ib leeg zuj zus rau txhua tus neeg mob. Cov tshuaj tuaj yeem noj tau ob qho ua ntej, tom qab, thiab ua ntej noj mov thaum lub sijhawm txhua hnub. Qhov ua tau zoo ntawm cov tshuaj los ntawm qhov no tsis txo qis.
Atomax sib txuas nrog lwm cov tshuaj li cas? Nyob rau hauv rooj plaub thaum thaum cov tshuaj siv ua ke nrog erythromycin lossis antifungal agents, phiv rau hauv daim ntawv ntawm myopia tuaj yeem tshwm sim. Atomax yuav tsum tsis txhob siv rau hauv kev txuas nrog kev ncua uas muaj hydroxide hauv txhuas, txwv tsis pub cov tshuaj atorvastatin hauv cov ntshav txo qis thiab cov txiaj ntsig ntawm kev kho, ntsig txog, kuj.
Terfenadine tuaj yeem siv tau, vim tias cov tshuaj hauv nqe lus nug hnub no tsis hloov pauv cov yam ntxwv ntawm yav dhau los. Nws tuaj yeem siv nrog estrogens - tsis muaj dab tsi loj yuav tshwm sim.
Tsis sib cav nrog Warfarin thiab Cimetidine.
Tsis txhob siv nrog cov tshuaj tiv thaiv protease, vim tias qhov kev sib xyaw no nce qhov kev coj ua ntawm cov tshuaj nquag ntawm Atomax. Nws yog ib qho tsim nyog yuav tsum cais tawm cov tshuaj tiv thaiv kab mob, lossis txo qhov ntau npaum. Qhov no yuav tsum tau ua raws li kev saib xyuas ntawm cov kws kho mob nkaus xwb.
Atomax yog yeeb ncuab ntawm cov cholesterol!
Qee lub sij hawm tib neeg tuaj yeem ntsib kev poob qis lossis nce ntxiv hauv kev ua yeeb yam ntawm qee yam yeeb tshuaj uas muaj nyob hauv lub cev thiab koom nrog kev ua haujlwm ntawm ntau lub nruab nrog cev thiab nruab nrog cev.
Txawm li cas los xij, nrog kev nce ntxiv hauv kev mloog zoo ntawm cov tshuaj xws li cov roj (cholesterol), nws feem ntau ua rau kev txhim kho ntawm ntau yam kabmob.
Txhawm rau rov qab nws, nrog rau kev tiv thaiv kev tshwm sim ntawm ntau yam teeb meem, Atomax feem ntau siv.
Cov tshuaj no muab tau ib txoj kev kho mob zoo heev.
Txhawm rau kom tsis txhob pom qhov tshwm sim ntawm kev phiv tshuaj, nws yog ib qho tsim nyog yuav tsum ua raws nraim li cov lus pom zoo ntawm cov kws kho mob koom nrog.
1. Cov lus qhia rau kev siv
Atomax yog lipid-txo tshuaj rau cov pab pawg neeg ntawm statins. Nws yog qhov sib tw xaiv cov tshuaj tiv thaiv ntawm HMG-CoA reductase koom nrog kev hloov pauv ntawm 3-hydroxy-3-methylglutaryl coenzyme A kom mevalonic acid molecules. Nws yog npaj los txo cov roj cholesterol, nrog rau cov lipoproteins ntshav muaj ntshav.
Qhov no yog vim muaj qhov tseeb tias inhibition ntawm HMG-CoA reductase tshwm sim, thiab kev sib sau ntawm cov roj (cholesterol) hauv cov qog hlwb qeeb qeeb.
Ntxiv rau, cov tshuaj no muaj txiaj ntsig zoo rau qhov kev nce ntawm LDL receptors nyob rau ntawm daim siab ua haujlwm ntawm cov nplooj siab, yog li txhim kho kev txhim kho thiab tom qab catabolism ntawm LDL lub tebchaw.
Raws li qhov tshwm sim, nws muaj qhov kev cim tseg txuas ntxiv rau qhov kev ua haujlwm ntawm LDL receptors. Kuj, nyob rau hauv cov mus tib seem, txoj kev pheej hmoo ntawm qhov tshwm sim ntawm ntau yam mob ischemic txo.
Nws yuav tsum nco ntsoov tias cov tshuaj tsis muaj qhov tshwm sim mutagenic lossis carcinogenic rau tib neeg lub cev.
Qhov tshwm sim ntawm kev kho mob tsis tu ncua tuaj yeem pom kwv yees li ob lub lis piam tom qab pib noj tshuaj. Qhov siab tshaj plaws tshwm sim tau pom tom qab ib hlis, thiab tom qab ntawd txuas ntxiv mus rau ib lub sijhawm ntev txaus.
Kev ntsuas rau nkag
Cov ntsiav tshuaj Atomax raug pom zoo kom coj los ua kom tau txais kev kho zoo ntawm cov kab mob zoo li no:
- Muaj zog ntau ntxiv ntawm LDL-C.
- Txhawb cov roj (cholesterol) tag nrho.
- Nce TG, ntxiv rau apolipoprotein B.
- Txhawb kev HDL-C ntsuas qhov sib xyaw nrog thawj hypercholesterolemia, ua ke hyperlipidemia, heterozygous tsis yog tsev neeg lossis tsev neeg hypercholesterolemia.
- Ua kom muaj ntshav ntau TG.
- Kev tsim kho ntawm dysbetalipoproteinemia.
Atomax yuav tsum tau coj los ua tshuaj ntxiv raug tshwj xeeb kev noj haus kev noj haus.
Txoj kev ntawm kev coj thiab ntau npaum
Ua ntej pib kev kho mob nrog cov tshuaj no, tus neeg mob yuav tsum ua raws li cov zaub mov lipid-txo cov zaub mov.
Qhov pom zoo kom pib noj yog 10 mg ib hnub ib zaug. Yog tias tsim nyog, nws tuaj yeem raug nce ntxiv rau 80 mg ib hnub ib zaug. Kev noj tshuaj tsis yog nyob ntawm lub sijhawm nruab hnub, nrog rau noj mov.
Cov neeg mob nrog hyperlipidemia sib xyaw lossis thawj hypercholesterolemia feem ntau yog cov tshuaj uas tau tshaj 10 mg ib hnub ib zaug.
3. Kev sib cuam tshuam txog yeeb tshuaj
Kev sib cuam tshuam ntawm Atomax ntsiav tshuaj nrog ntau yam tshuaj:
- Kev kho kev sib xyaw ua ke nrog kev siv "Erythromycin", "Cyclosporin", ntau yam fibrates, thiab ntxiv rau cov tshuaj tua kab mob uas koom nrog pab pawg azole, ua rau muaj kev pheej hmoo ntawm kev txhim kho myopathy.
- Kev siv lub zuj zus ntawm kev ncua, uas suav nrog txhuas hydroxide lossis magnesium hydroxide, yog vim li cas rau qhov txo qis hauv kev ua kom muaj zog ntawm cov tshuaj nquag ntawm cov tshuaj hauv cov ntshav ntshav.
- Kev sib xyaw ntawm Atomax nrog Antipyrine tsis ua rau lub luag haujlwm tseem ceeb hauv cov chaw muag tshuaj ntawm cov tom kawg. Yog li ntawd, nws tuaj yeem ua ke nrog cov tshuaj ntawm qhov muaj pes tsawg leeg zoo sib xws.
- Raws li qhov tshwm sim ntawm kev sib xyaw nrog "Colestipol," qhov kev txo qis ntawm cov tshuaj atorvastatin ntau ntxiv hauv cov ntshav ntshav tau pom. Hauv qhov no, ib qho kev txhim kho ntawm lipid-txo cov nyhuv.
- Nws muaj peev xwm nce siab ntxiv ua kom cov concentration ntawm "Digoxin" hauv cov ntshav ntshav. Yog li ntawd, nrog kev kho mob zoo li no, pom zoo kom tus neeg mob nyob hauv qab tswj hwm ntawm tus kws kho mob tshwj xeeb.
- Erythromycin, thiab Clarothromycin, ua rau nce qib ntawm cov tshuaj nquag ntawm Atomax ntsiav tshuaj muaj nyob hauv cov ntshav ntshav.
- Kev sib xyaw nrog cov tshuaj noj xws li Azithromycin tsis cuam tshuam rau qhov ua tau zoo ntawm atorvastatin hauv cov ntshav ntshav.
- Nws yog qhov ua tau los ua cov kev kho mob nyuaj nrog kev siv ncaj qha ntawm Terfenadine, vim tias Atomax tsis hloov nws lub zog.
- Kev siv Atomax tib lub sij hawm nrog ntau yam kev tiv thaiv qhov ncauj, uas muaj ethinyl estradiol nrog norethindrone, ua rau muaj kev cuam tshuam ntau ntxiv hauv AUC ntawm cov tshuaj no.
- Tsis muaj qhov tshwm sim uas tsis muaj kev cuam tshuam thaum tsis sib xyaw cov ntsiav tshuaj no nrog txhua yam tshuaj estrogens.
- Nws tsis paub yuav ua li cas Atomax cuam tshuam nrog ntau yam tshuaj tiv thaiv kev tiv thaiv.
- Tsis muaj kev sib txuam ntawm cov tshuaj ntawm cov tshuaj no nrog "Cimetidine", zoo li "Warfarin."
- Yog tias tsim nyog, cov tshuaj raug tso cai kom muab tso ua ke nrog cov neeg sawv cev uas muaj cov tshuaj amplodipine.
- Thaum ua ke nrog cov tshuaj tiv thaiv protease, muaj qhov nce ntxiv ntawm tus nqi ntawm atorvastatin ntau ntxiv hauv cov ntshav ntshav.