Finlepsin 400 retard - raug raws * cov lus qhia rau siv

Yog tias tsis muaj cov lus qhia tshwj xeeb ntawm koj tus kws kho mob, cov kev noj tshuaj hauv qab no yog siv tau rau finlepsin 400 retard. Thov ua raws li cov koob tshuaj uas koj tus kws kho mob sau tseg, vim yog txwv tsis pub finlepsin 400 retard yuav tsis muaj kev kho kom zoo!

Ntau npaum li cas thiab ntau npaum li cas yuav tsum koj noj finlepsin 400 retard

Kev kho nrog finlepsin 400 retard pib ua tib zoo, sau ntawv rau cov tshuaj hauv cov pa tshuaj tsawg kawg rau txhua tus neeg mob, nyob ntawm seb qhov xwm txheej thiab mob hnyav ntawm tus kab mob. Tom qab ntawd cov koob tshuaj tau maj mam nce kom txog thaum siv tshuaj kho kom zoo tiav los txog. Qhov zoo tshaj plaws ntawm lub khob tshuaj rau tus neeg mob, tshwj xeeb tshaj yog nrog kev sib txuam, yog txiav txim siab los ntawm nws cov ntshav theem. Raws li kev paub ntau zuj zus, kev kho mob concentration ntawm finlepsin 400 retard hauv cov ntshav ntshav yog 4–12 μg / ml.

Hloov ib qho tshuaj antiepileptic nrog finlepsin 400 retard yuav tsum ua maj mam ua, txo cov koob tshuaj ntawm cov tshuaj ua ntej siv. Yog tias ua tau, tus kab mob antiepileptic tsuas yog siv rau kev kho mob monotherapy. Lub chav kawm ntawm txoj kev kho yog saib xyuas los ntawm tus kws kho mob tshwj xeeb.

Feem ntau lees txais ntau npaum li cas yog 400–1200 mg ntawm finlepsin 400 retards ib hnub, uas tau muab faib ua 1-2 ib zaug ib hnub. Tshaj dhau qhov koob tshuaj txhua hnub ntawm 1400 mg tsis paub. Qhov siab tshaj plaws txhua hnub koob tshuaj yuav tsum tsis pub tshaj 1600 mg, vim tias cov koob tshuaj ntau dua tuaj yeem nce tus naj npawb ntawm kev phiv.

Qee qhov, cov koob tshuaj uas xav tau rau kev kho mob tuaj yeem ua rau txawv txav los ntawm cov lus pom zoo thawj zaug thiab txij nkawm, piv txwv, vim muaj cov metabolism nrawm nrawm vim yog lub induction ntawm microsomal daim siab enzymes, los yog vim muaj kev sib txuam tshuaj hauv kev kho ua ke.

Yog tias tsis muaj cov lus qhia tshwj xeeb los ntawm kws kho mob, lawv tau coj los ntawm cov qauv hauv qab no ntawm kev siv yeeb tshuaj:

Anticonvulsant kev kho mob

Feem ntau, rau cov neeg laus, thawj koob tshuaj 1 / 2–1 retard ntsiav tshuaj (sib haum rau 200-400 mg ntawm carbamazepine) yog maj mam nce ntxiv rau kev saib xyuas txij 2-3 koob tshuaj noj (sib haum rau 800 to1200 mg ntawm carbamazepine).

Cov sijhawm noj tshuaj hauv qab no yog kev pom zoo.

Cov neeg laus tau muab tshuaj rau yav sawv ntxov / yav tsaus ntuj200-300 mg thaum yav tsaus ntuj 200-600 mg 400-600 mg Cov menyuam raug khosaib ntawv los ntawm 6 txog 10 xyoo nyob rau yav tsaus ntuj200 mg nyob rau yav tsaus ntuj200 mg thaum sawv ntxov 200-400 mg 11 rau 15 xyoos thaum sawv ntxov / yav tsaus ntuj200 mg nyob rau yav tsaus ntuj200-400 mg 400-600 mg

Rau cov menyuam yaus hnub nyoog qis dua 6 xyoo, rau kev kho mob thawj zaug thiab txhawb nqa, cov ntsiav tshuaj ntawm qhov tsis ua raws sij hawm muaj. Vim yog qhov kev paub tsis txaus uas tau txais nrog cov ntsiav tshuaj rov qab, lawv tsis pom zoo rau cov menyuam yaus hnub nyoog no.

Kev tiv thaiv ntawm kev txhim kho kev qaug dab peg nrog kev haus cawv haus cawv hauv tsev kho mob

Qhov tshuaj nruab nrab txhua hnub yog 1/2 ntsiav tshuaj ntawm retard thaum sawv ntxov, thaum yav tsaus ntuj 1 ntsiav tshuaj ntawm kev rov qab yog qhov noj tshuaj (sib haum rau 600 mg ntawm carbamazepine). Hauv cov xwm txheej hnyav, hauv thawj hnub, cov koob tshuaj tuaj yeem raug nce ntxiv rau 1 thiab 1/2 ntsiav tshuaj ntawm retard 2 zaug hauv ib hnub (sib piv rau 1200 mg ntawm carbamazepine).

Finlepsin 400 retard yuav tsum tsis txhob txuam nrog cov tshuaj sedative-hypnotic. Ua raws li kev kho mob hauv tsev kho mob, txawm li cas los xij, yog tias tsim nyog, finlepsin 400 retard tuaj yeem ua ke nrog lwm cov tshuaj uas siv los kho cawv haus cawv.

Thaum kho, nws yog qhov yuav tsum tau soj ntsuam cov ntsiab lus ntawm finlepsin 400 retards hauv cov ntshav ntshav.

Hauv kev sib txuas nrog kev txhim kho kev mob tshwm sim los ntawm lub hauv nruab nrab thiab lub hlwb tsis zoo (saib cov xwm txheej ntawm kev haus dej haus cawv hauv ntu "Cov Kev Phom Sij"), cov neeg mob tau soj ntsuam kom zoo.

Ua rau mob hlwb neuralgia, genuin glossopharyngeal neuralgia

Thawj koob tshuaj yog 1 / 2–1 retard ntsiav tshuaj (sib haum rau 200–400 mg ntawm carbamazepine), uas, kom txog rau thaum qhov mob ploj tag, yog nce los ntawm qhov nruab nrab ntawm 1-2 retard ntsiav tshuaj (sib haum rau 400-800 mg ntawm carbamazepine), uas tau muab faib ua 1-2 ib leeg koob tshuaj ib hnub.Tom qab ntawd, nyob rau qee qhov ntawm cov neeg mob, kev kho mob tuaj yeem txuas ntxiv nrog kev tswj xyuas qis dua, uas tseem tuaj yeem tiv thaiv kev tawm tsam ntawm qhov mob ntawm 1/2 ntsiav tshuaj retard 2 zaug hauv ib hnub (sib raug rau 400 mg ntawm carbamazepine).

Rau cov neeg laus thiab cov neeg mob rhiab, finlepsin 400 retard yog qhov kev kho mob thawj zaug ntawm 1/2 ntsiav tshuaj ntawm cov retard ib hnub ib zaug (sib raug rau 200 mg ntawm carbamazepine).

Hnov mob ntshav qab zib neuropathy

Qhov nruab nrab cov tshuaj txhua hnub yog 1/2 ntsiav tshuaj rov qab thaum sawv ntxov thiab 1 ntsiav tshuaj rov qab yav tsaus ntuj (sib haum rau 600 mg ntawm carbamazepine). Hauv qee qhov tshwj xeeb, finlepsin 400 retard tuaj yeem kho nyob rau hauv lub koob tshuaj 1 thiab 1/2 ntsiav tshuaj retard 2 zaug hauv ib hnub (sib nug rau 1200 mg ntawm carbamazepine).

Kab mob vwm uas huam ntau yam mob sclerosis

Qhov nruab nrab txhua hnub koob tshuaj yog 1 / 2-1 retard ntsiav tshuaj 2 zaug hauv ib hnub (sib xyaw rau 400-800 mg ntawm carbamazepine).

Kev tiv thaiv ntawm theem manic-depressive

Thawj koob tshuaj, uas, raws li txoj cai, kuj txaus raws li kev saib xyuas txij nkawm, yog 1/2 /1 retard ntsiav tshuaj ib hnub (sib piv rau 200-400 mg ntawm carbamazepine). Yog tias tsim nyog, cov koob tshuaj no tuaj yeem raug ntxiv rau 1 ntsiav tshuaj retard 2 zaug hauv ib hnub (sib xyaw rau 800 mg ntawm carbamazepine).

Cov neeg mob uas muaj cov kab mob plawv heev, mob rau daim siab thiab lub raum, nrog rau cov neeg laus yuav tau txais tshuaj tsawg dua ntawm cov tshuaj.

Yuav ua li cas thiab thaum twg koj yuav tsum noj finlepsin 400 retard

Cov ntsiav tshuaj rov qab yog nruab nrog qhov zaws sib faib, lawv tau noj thaum lub sijhawm noj mov lossis tom qab noj mov, ntxuav nrog cov kua dej txaus (piv txwv li, khob dej).

Cov ntsiav tshuaj rov qab tuaj yeem nqa tom qab lawv thawj qhov kev cais tawm hauv dej (hauv qhov qauv ntawm kev ncua). Lub caij nyoog ntev mus ntev tsawv tom qab lub ntsiav tshuaj disintegrates hauv dej.

Qee qhov xwm txheej, muab faib rau cov koob tshuaj txhua hnub rau 4-5 koob tshuaj ib hnub ua rau muaj txiaj ntsig tshwj xeeb. Rau qhov no, ntau npaum li cas ntawm kev txiav txim siab uas tsis yog lub caij nyoog ntev yog qhov zoo tshaj.

Ntev npaum li cas koj yuav tsum noj finlepsin 400 retard

Lub sijhawm siv yog nyob ntawm qhov ntsuas thiab tus neeg teb ntawm tus neeg mob rau cov tshuaj.

Epilepsy kho tau ntev. Tus kws kho mob tshwj xeeb yuav tsum txiav txim siab hloov chaw ntawm tus neeg mob mus rau finlepsin 200 retard, lub sijhawm siv thiab nws tshem tawm hauv txhua kis. Feem ntau, koj tuaj yeem sim txo qis ntawm cov tshuaj los yog txiav tawm tag nrho cov kev kho mob tsis muaj ua ntej tshaj li tom qab 2-3 xyoo tsis muaj mob chua leeg.

Txoj kev kho tau raug tso tseg los ntawm kev txo qis zuj zus me me hauv lub sijhawm li 1-2 xyoo. Hauv qhov no, menyuam yuav tsum xav txog qhov nce hauv lub cev nyhav. Cov ntsuas qhov EEG yuav tsum tsis txhob ua kom qis.

Hauv kev kho mob ntawm neuralgia, nws tau muaj txiaj ntsig los muab tshuaj finlepsin 200 retard hauv ib qho kev kho mob, tsuas yog txaus los daws qhov mob, rau ob peb lub lis piam. Nrog kev ceev faj txo qis ntawm koob tshuaj, nws yog ib qho tsim nyog yuav tsum txiav txim siab seb puas muaj kev kho ntxiv los ntawm cov tsos mob ntawm tus kab mob tau tshwm sim. Nrog kev rov pib dua ntawm kev mob ntxiv, kho yog txuas ntxiv nrog cov koob tshuaj txij nkawm dhau los.

Lub sijhawm kho mob rau mob ntshav qab zib mob neuropathy thiab mob qaug dab peg hauv ntau yam sclerosis yog tib yam rau kev mob neuralgia.

Kev kho mob ntawm kev haus cawv haus syndrome nrog finlepsin 200 theem ntev ntev tau raug nres los ntawm kev txo qis koob tshuaj ntau dua lub sijhawm 7-10 hnub.

Kev tiv thaiv theem manic-depressive yog nqa tawm mus ntev.

Yuam kev ntawm kev siv cov tshuaj thiab overdose

Yog tias koj tsis nco qab noj ib zaug ntawm cov tshuaj, tom qab ntawd koj pom nws tam sim ntawd, siv tam sim ntawd. Yog tias sai sai tom qab qhov no koj yuav tsum noj tshuaj ntxiv tom qab, tom qab ntawd koj yuav hla nws, thiab tom qab ntawv sim rov nkag mus rau koj cov tshuaj noj kom raug. Txawm li cas los xij, tom qab hnov qab tsis nco qab lawm, tsis txhob noj ob zaug ntawm finlepsin 400 retard. Yog tias tsis ntseeg, thov hu rau koj tus kws kho mob kom pab!

Dab tsi koj yuav tsum xav txog yog tias koj xav cuam tshuam lossis ntxov ntxov tso tseg kev kho mob

Hloov cov koob tshuaj rau koj tus kheej lossis tseem txwv tsis pub siv tshuaj yam tsis tau saib xyuas kev kho mob yog txaus ntshai! Hauv qhov no, cov tsos mob ntawm koj tus kab mob tuaj yeem rov ua dua. Ua ntej koj tsum tsis noj Finlepsin 400 Rov ua haujlwm rau koj tus kheej, koj yuav tsum sab laj nrog koj tus kws kho mob txog qhov no.

Yuav ua li cas yog tias finlepsin 400 retard tau coj los hauv ntau qhov ntau

Kev siv ntau dhau ntawm cov tshuaj yuav tsum muaj kev kho mob thaum muaj xwm ceev. Daim duab overdose ntawm finlepsin 400 retard yog pom los ntawm kev nce ntxiv hauv cov kev mob tshwm sim xws li tshee tshee (tshee tshee), qaug dab peg uas tshwm sim thaum lub hlwb zoo siab (tonic-clonic convulsions), ntxhov siab, zoo li ua pa thiab mob plawv nrog feem ntau txo (qee zaum kuj nce siab) ntshav siab, nce lub plawv dhia (tachycardia) thiab cuam tshuam hauv kev tsis txaus siab hauv lub plawv (atrioventricular block, ECG hloov), tsis hnov qab nco txog ntawm kev ua pa tsis ua hauj lwm thiab mob raug ntes. Hauv cov xwm txheej cais, leukocytosis, leukopenia, neutropenia, glucosuria lossis acetonuria tau pom, uas tau tsim los ntawm cov kev ntsuas uas hloov kho ntawm kev kuaj sim.

Tsis muaj ib qho tshuaj tshwj xeeb rau kev kho mob ntawm kev mob hnyav nrog finlepsin 400 retard. Kev kho mob ntawm kev siv tshuaj ntau dhau ntawm finlepsin 400 retards, raws li txoj cai, yog nqa tawm nyob ntawm kev ua yeeb yam mob hauv tsev kho mob.

Pom cov kev mob tshwm sim ntau zaus tshwm sim nrog kev kho mob sib xyaw nrog kev kho mob hlwb. Nyob ntawm qhov koob tshuaj thiab feem ntau thaum pib kho, cov kev mob tshwm sim tom qab no tuaj yeem tshwm sim:

Kev Tsa Hauv Nruab Nrab / Lub Siab

Stupor ntawm nco qab, tsis meej pem nco qab (tsaug zog), kiv taub hau, qaug zog, tsis hnov qab thiab txav (cerebellar ataxia) thiab mob taub hau tuaj yeem tshwm sim. Cov neeg laus yuav ua rau muaj kev ntxhov siab thiab ntxhov siab.

Hauv cov xwm txheej cais, kev ntxhov siab tsis zoo lub siab, ua tus cwj pwm txhoj puab heev, ua kom qaug zog ntawm txoj kev xav, kev ua kom lub siab tsis zoo, nrog rau qhov pom kev tsis meej (pom kev sib cav) thiab tinnitus tau pom. Thaum kho nrog finlepsin 400 retard, cov hlwb latent yuav qhib tau.

Qhov tshwm sim hauv lub cev feem ntau tsis tshua tshwm sim, xws li co co co, mob pob tw, lossis txhaws qhov muag (nystagmus). Tsis tas li ntawd, nyob rau hauv cov neeg mob laus thiab cov mob hlwb, kev tsis sib haum ntawm cov kev sib txuas ntawm lub cev muaj zog tuaj yeem tshwm sim, xws li kev tsis tuaj yeem nyob hauv thaj av rotolitic nyob rau hauv daim ntawv ntawm grimacing (rotolitic dyskinesias), kev hloov mus ncig (choreoathetosis). Qee kis ntawm kev hais lus tsis meej, hnov qhov tsis meej, mob lub cev tsis muaj zog, mob hlab ntshav tawm (mob leeg), nrog rau kev ua rau lub cev txhaws qis (paresis) thiab saj pom kev tsis meej.

Feem ntau ntawm cov tshwm sim no ploj ntawm lawv tus kheej tom qab 8-14 hnub lossis tom qab txo qis cov tshuaj ib ntus. Yog li ntawd, yog tias ua tau, finlepsin 400 retard yog ua tib zoo dosed, pib kho nrog cov koob tshuaj qis, tom qab ntawd maj mam nce ntxiv.

Ob lub qhov muag

Muaj qee kis, muaj kev cuam tshuam ntawm kev sib txuas ntawm lub qhov muag (qhov muag tsis pom kev), qee zaum muaj kev cuam tshuam txog qhov muag tsis pom kev (qhov tsis haum ntawm lub qhov muag, ob lub zeem muag, qhov pom kev tsis pom kev). Cov xwm txheej ntawm clouding ntawm lub lens tau raug tshaj tawm.

Hauv cov neeg mob uas muaj mob txha cajqwm, nws yog qhov yuav tsum tau ntsuas cov leeg ntawm lub plab.

Propulsion system

Hauv cov kis mob sib cais, kev hnov mob tau pom nyob hauv cov pob qij txha thiab cov leeg (mob pob qij txha, myalgia), nrog rau cov leeg txhaws. Cov tshwm sim no ploj tom qab kev tshem tawm ntawm cov tshuaj.

Daim tawv nqaij thiab qog ua pa

Cov mob uas muaj kev tsis haum ntawm daim tawv nqaij muaj nrog lossis tsis kub taub hau tau tshaj tawm, xws li tsis tshua muaj lossis muaj ntau qhov mob ua pob (urticaria), khaus, qee zaum muaj phaj loj lossis tawv nqaij tawv nqaij tawv (ua kom mob dermatitis, erythroderma), necrosis ntawm thaj chaw ntawm daim tawv nqaij nrog blistering (syndrome) Lyell), kev tawm pob txha (ua kom lub ntsej muag), liab ntawm daim tawv nqaij nrog cov pob txuv polymorphic nyob rau hauv daim ntawv ntawm cov pob thiab tsim cov ntshav, nrog hemorrhages (exudative erythema multiforme, erythema nodosum, Stevens syndrome Johnson), petechial hemorrhages nyob rau hauv daim tawv nqaij, thiab mauj lupus erythematosus (lupus erythematosus disseminated).

Hauv cov chaw tsis muaj neeg lossis tsis tshua muaj, cov plaub hau ploj (alopecia) thiab tawm hws (diaphoresis) tau sau tseg.

Circulatory thiab lymphatic system

Hauv kev sib txuas nrog cov kev tsis haum siab hauv kev kho mob ntawm finlepsin 400 retards, ntxiv rau, cov kev cuam tshuam hauv qab no hauv daim duab ntshav yuav tshwm sim: tsis tshua muaj lossis feem ntau nce (leukocytosis, eosinophilia) lossis txo qis (leukopenia) hauv cov lej ntawm leukocytes lossis platelets (thrombocytopenia) hauv ntshav nruab nrog. Raws li cov ntaub ntawv, ib daim ntawv dhau los ua leukopenia feem ntau pom tshwm sim (hloov mus li ntawm 10% ntawm cov neeg mob, thiab pheej mob siab hauv 2% ntawm cov neeg mob).

Tshaj tawm ntawm cov kis mob sib kis ntawm cov ntshav, qee zaum txawm tias muaj kev phom sij txog lub neej, xws li agranulocytosis, aplastic anemia, nrog rau lwm hom kev mob ntshav tsis txaus (hemolytic, megaloblastic), nrog rau kev nce rau tus txha caj qaum thiab cov qog ntshav.

Nrog cov tsos ntawm leukopenia (feem ntau neutropenia), thrombocytopenia, ua pob ua xua ua pob tawv nqaij (exanthema) thiab kub taub hau finlepsin 400 retards tau muab tso tseg.

Lub plab zom mov

Qee zaum yuav tsis qab los noj mov, qhov ncauj qhuav, xeev siab thiab ntuav, raws plab los yog cem quav. Cais tawm los ntawm kev mob plab thiab mob ntawm lub caj pas ntawm txoj hlab pas oropharynx (stomatitis, gingivitis, glossitis) tau raug tshaj tawm. Cov tshwm sim no dhau los ntawm lawv tus kheej tom qab 8-14 hnub ntawm kev kho mob lossis tom qab txo qis ib ntus ntawm cov koob tshuaj. Lawv tuaj yeem zam tau los ntawm thawj lub sijhawm teem sijhawm qis ntawm cov tshuaj nrog lawv nce zuj zus.

Muaj cov kev qhia hauv cov ntaub ntawv hais tias carbamazepine qee zaum tuaj yeem ua rau mob ntawm tus kabmob (pancreatitis).

Mob siab thiab tsib bile

Qee zaum cov kev hloov pauv ntawm qhov ntsuas ntawm kev kuaj ntshav siab kuaj pom pom, muaj qee qhov mob daj ntseg pom tshwm sim; nyob rau hauv cov xwm txheej tsis tshua muaj, muaj ntau hom kab mob siab (cholestatic, hepatocellular, granulomatous, sib xyaw) tshwm sim.

Ob qho xwm txheej ntawm tus mob sib kis tsis tau muaj tau piav qhia.

Hormonal, dej thiab ntsev metabolism hauv

Cais tawm ntawm tus neeg mob lub mis o hauv cov txiv neej (gynecomastia) thiab cov tawm ntawm cov kua mis los ntawm cov qog mammary hauv cov poj niam (galactorrhea) tau raug tshaj tawm.

Finlepsin 400 retard tuaj yeem cuam tshuam cov thyroid ua haujlwm tsis sib haum (triiodothyronine, thyroxine, thyroid stimulating hormone thiab pub dawb thyroxine), tshwj xeeb tshaj yog thaum ua ke nrog lwm cov tshuaj tiv thaiv antiepileptic.

Vim qhov kev txiav txim ntawm finlepsin 400 retard, uas txo qis kev tso zis ntawm lub cev (cov nyhuv antidiuretic), nyob rau hauv cov xwm txheej tsis tshua muaj, qhov kev txo qis ntawm cov dej qab ntsev (hyponatremia) tuaj yeem pom, nrog ntuav, mob taub hau thiab tsis meej pem.

Cov xwm txheej cais ntawm cov tsos ntawm edema thiab nce hauv lub cev qhov hnyav tau pom. Finlepsin 400 Retard yuav qis cov calcium ntau ntau. Hauv cov kis ua mob, qhov no ua rau cov pob txha mos (osteomalacia).

Kab mob plab hnyuv siab raum

Cov teeb meem sib cais ntawm cov tshuaj tiv thaiv ntawm cov neeg mob ntsws ntau ntxiv rau cov tshuaj, nrog kub taub hau, ua pa luv (ua pa), mob ntsws thiab mob ntsws ntsws, tau piav.

Tub sab caj pa

Tsis tshua muaj qhov ua rau lub raum khiav tsis zoo, qhia los ntawm qhov muaj protein ntau hauv cov zis (cov proteinuria), cov ntshav hauv cov zis (hematuria), tsis tuaj yeem tso zis (oliguria), nyob rau qee qhov tsis tshua muaj tshwm sim ua rau lub raum tsis ua haujlwm. Tej zaum cov kev tsis zoo no yog vim muaj qhov ua tib zoo siv tshuaj tiv thaiv cov tshuaj. Qee zaum dysuria, pollakiuria thiab tso zis tawm tsam.

Tsis tas li ntawd, muaj cov neeg paub txog kev sib daj sib deev, xws li tsis muaj zog thiab tsis muaj siab rau kev sib deev.

Kev kho plawv

Tsis tshua muaj lossis qee qhov mob, feem ntau yog rau cov neeg laus lossis cov neeg mob uas paub tias mob plawv tsis ua haujlwm, txo lub plawv dhia (bradycardia), mob plawv atherosclerosis, thiab kev mob ntshav siab rau lub plawv yuav tshwm sim.

Tsis tshua muaj kev ua txhaum ntawm qhov tsis txaus siab nyob rau hauv lub siab (atrioventricular block), hauv cov teeb meem sib cais nrog fainting. Ntxiv mus, hauv qee kis, cov ntshav siab poob qis lossis nce siab. Kev poob hauv cov ntshav siab feem ntau tshwm sim nrog kev siv cov tshuaj hauv qhov siab.

Ib qho ntxiv, vasculitis, thrombophlebitis, thiab thromboembolism tau pom.

Kev ua haujlwm tsis haum siab

Ncua kev cuam tshuam ntawm qhov tsis haum siab rau qhov tshuaj tsis tshua tshwm sim, tshwm sim kub taub hau, tawm pob ntawm daim tawv nqaij, vascular o, mob rau cov qog ntshav, mob pob qij txha, ntau cov leukocytes nyob rau hauv cov ntshav nruab nrab, ua kom lub siab thiab tus po, thiab qhov hloov pauv ntawm lub siab ua haujlwm kuaj uas tuaj yeem tshwm sim sib txawv kev sib xyaw ua ke, thiab tseem muaj feem nrog lwm cov plab hnyuv siab raum hauv cov txheej txheem, xws li lub ntsws, lub raum, txiav thiab myocardium.

Hauv cov kis mob cais, kev tiv thaiv kab mob dav dav thiab cov mob ua paug rau cov hlab ntshav nrog myoclonus thiab eosinophilia tau pom.

Yog tias koj pom cov kev mob tshwm sim uas tsis hais hauv cov lus ceeb toom no, thov qhia rau koj tus kws kho mob lossis kws muag tshuaj txog qhov no.

Dab tsi ntsuas yuav tsum tau ua nrog kev phiv

Yog tias koj pom cov kev mob tshwm sim saum toj no, tom qab ntawv ceeb toom rau koj tus kws kho mob tam sim ntawd uas yuav txiav txim siab lawv qhov mob hnyav thiab siv kev ntsuas los tawm tsam lawv (saib tshooj "Kev Ceeb Toom rau kev siv"). Tshwj xeeb tshaj yog thaum muaj kub ib ce, mob caj pas, ua xua ntawm daim tawv nqaij ua pob ua xua nrog ua mob rau cov qog ntshav thiab / lossis zoo li mob khaub thuas zoo li cov tsos mob thaum kho nrog finlepsin 400 retards, koj yuav tsum tam sim ntawd sab laj nrog kws kho mob thiab soj ntsuam daim duab ntshav.

Nrog rau kev txhim kho ntawm kev fab tshuaj tsis haum, finlepsin 400 retard yog tam sim ntawd tso tseg.

Yog tias qee yam kev hloov hauv cov ntshav ntshav tau tshwm sim (leukopenia, ntau zaus neutropenia, thrombocytopenia), ua pob ntawm daim tawv nqaij ua xua (exanthema) thiab kub taub hau finlepsin 400 retards tau muab tso tseg.

Yog tias muaj cov cim qhia ntawm daim siab ua rau lub siab puas los yog ua haujlwm tsis zoo, xws li lub siab tsis txaus, tsis qab los noj mov, xeev siab, daj tawv nqaij lossis ua kom lub siab nce siab, tam sim ntawd sab laj nrog kws kho mob.

Hnub siv tshuaj yaj yeeb

3 xyoos
Lub txee lub neej ntawm cov ntsiav tshuaj retard yog qhia rau ntawm cov ntawv ci ntawm lub ntsej muag blister ntim thiab rau ntawm lub thawv ntawv thawv.
Tom qab lub sijhawm tau teev tseg, tsis txhob siv ntau dua cov ntsiav tshuaj rov qab ntawm pob ntawv no.

Tshuaj muab tshuaj cia kom ncav tsis cuag cov menyuam!

Finlepsin 400 Retard los rau hauv cov menyuam yaus muaj kev nyab xeeb ntim nrog cov ntawv ci tuab dua. Nyob rau hauv rooj plaub nws yog qhov nyuaj rau koj los nyem lub ntsiav tshuaj retard, tom qab ntawd ua ntej koj ua qhov no, peb qhia koj kom me ntsis incise ntawv ci los npog.

Cia rau cov neeg mob

Cov tshuaj no yog muab cia rau hauv ib qho kev mob ib txwm.

Tso Tawm Cov Ntawv

Finlepsin 400 retard muaj nyob rau hauv pob ntawm 50, 100, thiab 200 retard ntsiav tshuaj.

Cov yam ntxwv Pharmacological:

Antiepileptic siv yeeb siv tshuaj (dibenzazepine derivative), uas kuj muaj cov tshuaj normotymic, antimaniacal, antidiuretic (hauv cov neeg mob ntshav qab zib insipidus) thiab analgesic (hauv cov neeg mob neuralgia). Lub tshuab ntawm kev ua yog txuam nrog qhov thaiv ntawm voltage-gated Na + channels, uas ua kom muaj kev ruaj khov ntawm cov neuron membrane, inhibition ntawm cov tsos ntawm cov feem ntawm kev puas tsuaj ntawm neurons thiab txo qis ntawm kev sib txuas ntawm lub zog. Tiv thaiv qhov rov tsim ntawm Na + -cov kev txiav txim siab lub peev xwm hauv depolarized neurons.Txo kev tso tawm ntawm qhov txaus siab neurotransmitter amino acid glutamate, nce qhov txo qhov qaug dab peg tsawg, thiab lwm yam. txo txoj kev pheej hmoo ntawm kev tsim muaj mob chwv leeg. Nws tsub kom qhov conductivity rau K +, modulates voltage-gated Ca2 + channels, uas tseem tuaj yeem ua rau cov nyhuv anticonvulsant ntawm cov tshuaj. Kho cov kev puas ntsoog tus kab mob hloov pauv thiab thaum kawg ua rau muaj kev cia siab rau cov neeg mob, pab txhawb lawv cov kev tsim kho kom rov qab zoo li qub. Nws tuaj yeem raug suav tias yog cov tshuaj kho mob tseem ceeb thiab hauv kev sib xyaw nrog lwm cov tshuaj anticonvulsant. Nws yog qhov zoo rau focal (ib nrab) qaug dab peg (yooj yim thiab txoj), nrog los yog tsis nrog los ntawm kev muaj feem thib ob, rau kev kho tus mob feem ntau tonic-clonic mob chua leeg, nrog rau kev sib xyaw ntawm cov hom no (feem ntau tsis muaj txiaj ntsig rau me me qaug dab peg - tso quav mal, tsis tuaj thiab myoclonic qaug dab peg) Cov. Cov neeg mob qaug dab peg (tshwj xeeb tshaj yog nyob rau cov menyuam yaus thiab cov hluas) muaj cov txiaj ntsig zoo ntawm cov tsos mob ntawm kev ntxhov siab thiab kev nyuaj siab, nrog rau kev txo qis kev txob taus thiab kev txhoj puab heev. Qhov kev cuam tshuam ntawm kev txawj ntse ntawm lub hlwb kev ua haujlwm thiab psychomotor kev ua tau zoo yog qhov koob tshuaj thiab muaj kev hloov siab. Qhov pib ntawm cov nyhuv anticonvulsant sib txawv los ntawm ob peb teev mus rau ntau hnub (qee lub sijhawm txog li 1 hlis vim kev pib-pib ntawm cov metabolism). Nrog rau qhov tseem ceeb thiab theem siab trigeminal neuralgia feem ntau nws txwv tsis pub muaj qhov tsos ntawm qhov mob tawm tsam. Ua tau zoo rau txo cov mob neurogenic nyob rau hauv dryness ntawm tus txha nqaj qaum, mob nraub qaum tom qab lub cev thiab tom qab mob hlwb. Kev kho mob qhov mob nyob rau hauv trigeminal neuralgia tau sau tseg tom qab 8-72 teev. Nrog rau haus dej haus cawv mob siab, nws nce qhov qaug dab peg (uas feem ntau txo qis hauv qhov mob no) thiab txo qhov mob ntawm cov kev mob tshwm sim ntawm tus mob (nce ntxiv kev chim siab, tshee, gait mob). Hauv cov neeg mob uas muaj ntshav qab zib insipidus ua rau sai sai them nyiaj ntawm cov dej tshuav, txo cov diuresis thiab nqhis dej. Antipsychotic (antimaniacal) kev ua tom qab 7-10 hnub, tuaj yeem yog vim yog inhibition ntawm cov metabolism hauv dopamine thiab norepinephrine. Daim ntawv noj tshuaj ntau dua ua rau muaj kev saib xyuas ntawm lub zog ruaj khov dua ntawm cov carbamazepine hauv cov ntshav tsis muaj "peaks" thiab "dips", uas tso cai rau txo qhov zaus thiab qhov mob ntawm cov teeb meem tsis zoo ntawm kev kho, kom nce cov txiaj ntsig ntawm kev kho mob txawm tias siv cov koob tshuaj uas tsis tshua muaj. Dr. qhov txiaj ntsig tseem ceeb ntawm daim ntawv ntev ntev yog qhov ua tau ntawm kev noj 1-2 zaug ib hnub.

Kev taw qhia rau kev siv:

• qaug dab peg: ntuag ib nrab nrog cov tsos mob thaum pib (focal seizures), chua leeg ib nrab nrog cov tsos mob nyuaj (mob hlwb), loj chua leeg, feem ntau yog focal keeb kwm (loj qaug dab peg thaum pw tsaug zog, qaug dab peg), sib xyaw hom mob vwm,
• trigeminal neuralgia,
• mob paroxysmal ntawm qhov tsis paub tshwm sim ntawm ib sab ntawm lub hauv paus ntawm tus nplaig, pharynx thiab cov tawv muag ntawm lub ntsej muag (genuin glossopharyngeal neuralgia)
• mob nrog mob txhab tawm ntawm lub paj hlwb txhaws hauv ntshav qab zib mellitus (mob mob ntshav qab zib neuropathy),
• mob vwm epileptiform mob ua ke hauv ntau yam sclerosis, xws li txhaws ntsej muag hauv pob txha caj qaum mob hauv lub cev ua pob txha caj qaum, mob caj dab ua kom leeg to taub, hais lus tsis meej thiab muaj kev cuam tshuam (paroxysmal dysarthria thiab ataxia), tsis xis nyob (paroxysmal paresthesia) thiab mob mob,
• tiv thaiv kev txhim kho kev qaug dab peg hauv cov neeg haus cawv haus yeeb tshuaj,
• hlwb hlwb (feem ntau hauv manic-depressive xeev, hypochondriacal kev nyuab siab). Kev tiv thaiv thib ob ntawm kev cuam tshuam thiab schizoaffective psychoses.

Ceeb Toom: txhawm rau tiv thaiv kev txhim kho kev mob nriaj nrog dej cawv tshem tawm mob, finlepsin tsuas yog siv rau hauv tsev kho mob chaw.

Daim Ntawv Thov Nta:

Hauv kev sib txuas nrog qhov tshwm sim uas tshwm sim ntawm kev mob tshwm sim, nrog rau cov tshuaj tiv thaiv ntawm qhov tsis txaus siab rau qhov tshuaj, nws raug nquahu, tshwj xeeb tshaj yog nrog kev siv lub sijhawm ntev, txhawm rau soj ntsuam cov ntshav txawv thiab kuaj xyuas lub siab ua haujlwm thiab lub raum. Qhov no yog ua ua ntej pib kev kho mob, tom qab ntawd hauv thawj lub hlis ntawm kev kho mob ib zaug ib lim tiam, thiab tom qab ntawd ib hlis ib zaug. Tom qab thawj 6 lub hlis ntawm kev kho mob, cov kev tswj hwm no tau ua tiav 2 times4 zaug ib xyoo.

Tib txoj kev, kev saib xyuas ntawm finlepsin 400 retard thiab lwm cov tshuaj antiepileptic nyob rau hauv cov ntshav ntshav yuav tsum raug saib xyuas tsis tu ncua thaum muaj kev sib xyaw ua ke thiab, yog tias tsim nyog, txo qis txhua hnub.

Qhov xaus ntawm kev kho mob nrog finlepsin 400 retards hauv cov neeg mob epilepsy thiab lawv hloov mus rau lwm cov tshuaj tiv thaiv kho mob tsis tau ua sai sai, tab sis maj mam txo qis dua cov koob tshuaj.

Hauv cov neeg mob uas muaj mob txha cajqwm, ntshav siab ntawm lub plab yog soj ntsuam tas li. Nws yuav tsum tau yug hauv siab tias qhov kev phiv los ntawm finlepsin 400 retard hauv kev kho mob ntawm kev haus cawv haus cawv muaj qhov zoo sib xws rau kev tshem tawm cov tsos mob thiab tuaj yeem yooj yim nrog lawv.

Yog tias muaj qee qhov tshwj xeeb rau kev tiv thaiv manic-depressive theem nrog cov tsis muaj txiaj ntsig ntawm ib lub lithium, finlepsin 400 retard yuav tsum tau muab nrog nws, tom qab ntawd kom tsis txhob muaj kev sib txuam tsis zoo (saib "Kev cuam tshuam nrog lwm cov tshuaj"), nws yog qhov tsim nyog los xyuas kom meej tias qee qhov kev txiav txim ntawm carbamazepine tsis dhau nyob rau hauv cov ntshav ntshav (8 μg / ml), cov ntsiab lus lithium tau raug tswj nyob hauv qhov kho qis tsawg (0.3-0.8 mEq / l), tshuaj tiv thaiv kev kho mob tau ua tiav ntau tshaj 8 lub lis piam dhau los , thiab tseem kom nws tsis nqa tawm ib txhij.

Kev siv cov tshuaj thaum siv cov cav tov thiab thaum ua haujlwm tsis tas yuav ua kom tsis muaj kev cai saib xyuas kev nyab xeeb

Hauv kev sib txuas nrog qhov tshwm sim ntawm kev mob tshwm sim los ntawm lub hauv nruab nrab lub paj hlwb thaum pib kho, xws li kiv taub hau, tsaug zog, gait tsis ruaj ntseg thiab mob taub hau, thaum cov tshuaj siv rau hauv siab thiab / lossis thaum sib xyaw nrog lwm cov tshuaj uas cuam tshuam rau hauv nruab nrab lub paj hlwb, finlepsin 400 rov ua haujlwm, txawm tias siv qhov yog - tsis hais txog qhov cuam tshuam los ntawm kev kho tus kabmob tseem ceeb - tuaj yeem hloov koj qhov kev hloov pauv ntawm txoj kev uas koj tsis tuaj yeem koom nrog hauv kev tsheb mus ntxiv AI los yog nyiaj hauv lub tshuab.

Koj kuj tuaj yeem tsis tuaj yeem ceev nrooj thiab mob siab rau cov xwm txheej tsis tau pom. Koj yuav tsum tsis txhob tsav tsheb lossis thauj lwm yam! Koj yuav tsum tsis txhob siv cov cuab yeej hluav taws xob txiav lossis lub tshuab pabcuam! Koj yuav tsum tsis txhob ua haujlwm yam tsis tau saib xyuas cov cai muaj kev nyab xeeb! Tshwj xeeb nco ntsoov tias dej cawv tuaj yeem ntxiv ua rau koj lub peev xwm tsis muaj zog sai sai thaum koom nrog hauv tsheb.

Phiv los sis:

Kev Tsa Hauv Nruab Nrab / Lub Siab

Hauv cov neeg mob uas muaj mob txha cajqwm, nws yog qhov yuav tsum tau ntsuas cov leeg ntawm lub plab.

Daim tawv nqaij thiab qog ua pa

Hauv cov chaw tsis muaj neeg lossis tsis tshua muaj, cov plaub hau ploj (alopecia) thiab tawm hws (diaphoresis) tau sau tseg.

Circulatory thiab lymphatic system

Nrog cov tsos ntawm leukopenia (feem ntau neutropenia), thrombocytopenia, ua pob ua xua ua pob tawv nqaij (exanthema) thiab kub taub hau finlepsin 400 retards tau muab tso tseg.

Muaj cov kev qhia hauv cov ntaub ntawv hais tias carbamazepine qee zaum tuaj yeem ua rau mob ntawm tus kabmob (pancreatitis).

Ob qho xwm txheej ntawm tus mob sib kis tsis tau muaj tau piav qhia.

Hormonal, dej thiab ntsev metabolism hauv

Cais tawm ntawm tus neeg mob lub mis o hauv cov txiv neej (gynecomastia) thiab cov tawm ntawm cov kua mis los ntawm cov qog mammary hauv cov poj niam (galactorrhea) tau raug tshaj tawm.

Cov teeb meem sib cais ntawm cov tshuaj tiv thaiv ntawm cov neeg mob ntsws ntau ntxiv rau cov tshuaj, nrog kub taub hau, ua pa luv (ua pa), mob ntsws thiab mob ntsws ntsws, tau piav.

Tsis tas li ntawd, muaj cov neeg paub txog kev sib daj sib deev, xws li tsis muaj zog thiab tsis muaj siab rau kev sib deev.

Ib qho ntxiv, vasculitis, thrombophlebitis, thiab thromboembolism tau pom.

Kev ua haujlwm tsis haum siab

Hauv cov kis mob cais, kev tiv thaiv kab mob dav dav thiab cov mob ua paug rau cov hlab ntshav nrog myoclonus thiab eosinophilia tau pom.

Yog tias koj pom cov kev mob tshwm sim uas tsis hais hauv cov lus ceeb toom no, thov qhia rau koj tus kws kho mob lossis kws muag tshuaj txog qhov no.

Dab tsi ntsuas yuav tsum tau ua nrog kev phiv

Nrog rau kev txhim kho ntawm kev fab tshuaj tsis haum, finlepsin 400 retard yog tam sim ntawd tso tseg.

Kev cuam tshuam nrog lwm cov tshuaj:

Cov tshuaj dab tsi hloov qhov tshwm sim ntawm finlepsin 400 retard lossis cov tshuaj dab tsi hloov pauv ntawm finlepsin 400 retard?

Hauv kev sib txuas nrog kev txhim kho kev mob tshwm sim los ntawm lub hauv nruab nrab cov hlab ntaws, cov kev sib xyaw ua ke ntawm finlepsin 400 retards nrog monoamine oxidase inhibitors (cov tshuaj tiv thaiv kev ntxhov siab) yuav tsum zam. Thaum hloov los ntawm ib cov tshuaj rau lwm, lawv siv sijhawm 14-hnub so hauv kev kho!

Cov nyhuv ntawm finlepsin 400 rov tshwm sim ntawm qhov kev nkag siab ntawm lwm cov tshuaj hauv ntshav ntshav

Finlepsin 400 retard tuaj yeem nce cov kev ua haujlwm ntawm qee yam kab mob siab thiab ua rau qis dua lwm yam tshuaj hauv cov ntshav ntshav.

Yog li no, qhov tshwm sim ntawm qee lwm yam thooj txhij siv tshuaj, uas nws cov qauv tshuaj yog ze rau finlepsin 400 retards, tej zaum yuav tsis muaj zog lossis tsis txawm tshwm sim txhua.

Nrog tib lub sijhawm siv finlepsin 400 retard, raws li kev siv tshuaj, yog tias tsim nyog, kho cov koob tshuaj ntawm cov tshuaj sib txuas hauv qab no: clonazepam, ethosuximide, primidone, valproic acid, lamotrigine (lwm yam tshuaj rau kev kho mob vwm), alprazolam, clobazam (cov tshuaj uas pab txo kev ntshai), corticosteroids (piv txwv , prednisolone, dexamethasone), cyclosporine (ib qho cuab yeej siv rau kev tiv thaiv kev tiv thaiv lub cev tiv thaiv kab mob tom qab hloov khoom nruab nrog), digoxin (ib qho cuab yeej siv los kho cov mob plawv), tetras cov mob cyins, xws li doxycycline (ib qho tshuaj tiv thaiv), felodipine (ib qho tshuaj kho ntshav siab), haloperidol (tshuaj kho mob hlwb), imipramine (tshuaj tiv thaiv kab mob), tshuaj txiav yeeb (tshuaj tua mob), theophylline (cov tshuaj rau kev kho mob hnyav) mob ua pa), anticoagulants, xws li warfarin, fenprocoumon, dicumarol. Ib yam li lwm cov tshuaj tiv thaiv kab mob, finlepsin 400 retard tuaj yeem ua kom tsis muaj zog ntawm cov tshuaj tiv thaiv hormonal (tshuaj tiv thaiv kev xeeb tub, qhov sib "ncoo"). Cov tsos ntawm intermenstrual los ntshav qhia tias tsis txaus ntseeg tiv thaiv los ntawm cev xeeb tub los ntawm cev xeeb tub. Yog li ntawd, nyob rau hauv cov xwm txheej zoo li no, nws raug nquahu kom siv lwm txoj kev tiv thaiv kom tsis muaj menyuam.

Finlepsin 400 retard tuaj yeem ob qho tib si nce thiab txo qhov kev txiav txim siab ntawm phenytoin hauv cov ntshav ntshav, vim li ntawd, ntawm qhov xwm txheej tshwj xeeb, kev tsis meej pem tuaj yeem tshwm sim los ntawm kev txhim kho tsis nco qab.

Txo cov kev xav ntawm finlepsin 400 retard hauv cov ntshav ntshav nrog lwm yam tshuaj

Qib ntawm finlepsin 400 retard hauv cov ntshav ntshav tuaj yeem qis dua: phenobarbital, primidone, valproic acid, theophylline.

Ntawm qhov tod tes, valproic acid thiab primidone tuaj yeem nce qib ntawm pharmacologically nquag metabolite (cov khoom lag luam metabolic ntawm finlepsin 400 retard) carbamazepine - 10,11 - epoxide hauv cov ntshav cov ntshav.

Vim tias muaj kev sib txuam ntawm lwm tus, tshwj xeeb nrog kev siv cov tshuaj tiv thaiv ntau yam tshuaj tiv thaiv kab mob, nws raug nquahu kom tswj lawv cov plasma cov ntsiab lus thiab, yog tias tsim nyog, kho qhov ntau npaum ntawm finlepsin 400 retard.

Ib qho kev nce ntxiv ntawm cov concentration ntawm finlepsin 400 retard nyob rau hauv cov ntshav ntshav nrog lwm yam tshuaj

Cov tshuaj yeeb dej caw nram qab no tuaj yeem nce qhov siab ntawm finlepsin 400 retard nyob rau hauv cov ntshav ntshav: tshuaj tua kab mob - macrolides, xws li erythromycin, josamycin (cov tshuaj nquag rau kev kho cov kab mob),isoniazid (ib hom tshuaj rau kev kho mob ntsws), viloxazine (ib qho tshuaj tiv thaiv kab mob), danazol (tshuaj rau kev tiv thaiv kev sib deev tsis pub leej twg paub), acetazolamide (ib yam tshuaj rau kev kho qog ntshav), viloxazine (ib qho tshuaj tiv thaiv kev tiv thaiv), danazol (ib yam tshuaj rau kev tiv thaiv kev sib deev) gonadotropin hormone), nicotinamide hauv kev txhaj tshuaj ntau hauv cov neeg laus (vitamin B pawg), kuj tseem muaj cimetidine (ib yam tshuaj rau kev kho mob plab zom mov) thiab desipramine (antide compressively txhais tau tias).

Txhawb kev qib siab kawg ntawm finlepsin 400 retard hauv cov ntshav plasma tuaj yeem ua rau muaj kev loj hlob ntawm cov tsos mob uas tau hais hauv ntu "phiv los ntawm Sab Nraud" (piv txwv li kiv taub hau, nkees nkees, gait tsis nyab xeeb, ob lub zeem muag). Yog li, thaum muaj cov tsos mob no tshwm sim, kev saib xyuas ntawm carbamazepine nyob rau hauv cov ntshav ntshav yog saib xyuas thiab, yog tias tsim nyog, qhov koob tshuaj yuav raug txo.

Kev siv tib lub sijhawm ntawm finlepsin 400 retards thiab tshuaj tiv thaiv kev tiv thaiv (tshuaj rau kev kho mob hlwb) lossis metoclopramide (ib yam tshuaj rau kev kho mob plab hnyuv) tuaj yeem ua rau muaj tshwm sim ntawm cov leeg mob neurological.

Ntawm qhov tod tes, hauv cov neeg mob kho nrog kev tiv thaiv kev tiv thaiv kab mob, finlepsin 400 retard tuaj yeem txo qis cov tshuaj no hauv cov ntshav ntshav thiab yog li ua rau cov duab ntawm kab mob. Yog li, tus kws kho mob yuav txiav txim siab tias nws tsim nyog txhawm rau txhawm rau txhawm rau coj cov tshuaj tiv thaiv kev ntxhov siab.

Nws tau qhia tias tshwj xeeb tshaj yog nrog kev siv tib lub sijhawm lithium (ib yam tshuaj rau kev kho thiab tiv thaiv qee yam kev mob hlwb) thiab finlepsin 400 retard, qhov cuam tshuam ntawm ob qho tshuaj nquag uas ua rau cov leeg hlwb puas tsuaj tuaj yeem ua kom zoo dua. Yog li ntawd, nyob rau hauv cov xwm txheej zoo li no, nws yog ib qho tsim nyog yuav tsum ua tib zoo saib xyuas cov ntsiab lus ntawm ob qho tshuaj hauv ntshav ntshav. Cov kev kho mob yav dhau los nrog tshuaj tiv thaiv kab mob yuav tsum tau tsum tsis txhob ntxiv 8 lub lis piam ua ntej pib kho nrog cov tshuaj no, thiab yuav tsum tsis txhob nqa nrog lawv. Nws yog ib qho tsim nyog yuav tau soj ntsuam cov tsos ntawm cov tsos mob hauv qab no ntawm cov kev mob tshwm sim ntawm neurotoxic: gait tsis meej (ataxia), kev sib tw lossis kev tshee ntawm lub pob muag (kab rov tav nystagmus), nce ntawm cov leeg mob ntawm cov nqaij ntshiv pob txha, kev nrawm nrawm ntawm cov leeg nqaij (fibrillar twitches), kev tsis txaus siab ntawm ib leeg ntawm cov leeg nqaij (fascia) Cov.

Finlepsin 400 retard tuaj yeem txhim kho cov nyhuv ntawm isoniazid, uas ua rau lub siab.

Kev siv ua ke ntawm finlepsin 400 retard nrog qee cov diuretics (hydrochlorothiazide, furosemide) tuaj yeem ua rau kom cov sodium txo hauv cov ntshav cov ntshav tsawg.

Finlepsin 400 retard tuaj yeem cuam tshuam rau qhov ua tau zoo ntawm cov tshuaj uas ua kom cov leeg mob (leeg ua kom lub zog), xws li pancuronium. Raws li qhov no, kev tshem tawm sai dua ntawm cov neuromuscular yog ua tau. Yog li, cov neeg mob kho nrog cov leeg ib ce muaj zog yog saib xyuas thiab, yog tias tsim nyog, tau nce ntxiv ntawm cov tshuaj no.

Nrog rau kev siv isotretinoin tib lub sijhawm (ib yam tshuaj rau kev kho pob txuv) thiab finlepsin 400 retard, cov ntsiab lus ntawm finlepsin 400 retard hauv cov ntshav cov ntshav yuav tsum tau saib xyuas.

Finlepsin 400 qeeb qeeb tej zaum pab txhim kho kev tshem tawm (tshem tawm) ntawm cov thyroid hormones thiab nce qhov kev xav tau rau lawv hauv cov neeg mob uas txo cov thyroid muaj nuj nqi. Yog li, hauv cov neeg mob no tau txais kev kho mob hloov, thaum pib thiab thaum kawg ntawm kev kho mob nrog finlepsin 400 retards, cov thyroid muaj nuj nqi ntsuas tau txiav txim siab. Yog tias tsim nyog, kho qhov koob tshuaj ntawm cov thyroid hormones txaus npaj.

Nrog rau kev siv cov tshuaj tiv thaiv ib puag ncig xws li serotonin reuptake blockers (cov tshuaj tiv thaiv kab mob, xws li fluoxetine) thiab finlepsin 400 retard, lom serotonin syndrome tuaj yeem tsim kho.

Nco ntsoov tias cov ntaub ntawv no tseem yuav cuam tshuam rau cov tshuaj noj ua ntej pib kev kho mob nrog finlepsin 400 retard.

Dab tsi stimulants, tais diav thiab haus dej koj yuav tsum tsis kam

Thaum kho nrog finlepsin 400 retard, koj yuav tsum tso tseg kev haus cawv, vim tias nws tuaj yeem tsis tuaj yeem hloov pauv thiab txhim kho cov nyhuv ntawm finlepsin 400 retard.

Cov Tshuaj Tiv Thaiv:

Finlepsin 400 retard yog contraindicated nyob rau hauv rooj plaub ntawm: muaj pob txha muaj kev puas tsuaj, cuam tshuam nyob rau hauv kev txaus siab nyob rau hauv lub plawv (atrioventricular block), paub hypersensitivity rau lub active tshuaj, tricyclic antidepressant tshuaj los yog rau ib qho ntawm lwm yam (saib "Sib Sau"), raws li zoo raws li rau mob siab sib quas ntus porphyria (ib yam mob muaj keeb hauv qhov sib pauv ntawm porphyrins).

Finlepsin 400 retard yuav tsum tsis txhob siv ib txhij nrog lithium npaj (saib "Kev cuam tshuam nrog Lwm Yam Tshuaj").

Txij li thaum finlepsin 400 retard tuaj yeem tsim txoj kev tshiab lossis ntxiv dag zog rau cov kev foob tshwj xeeb (qhov tsis tuaj kawm ntawv), nws tsis pom zoo kom xaiv nws rau cov neeg mob uas mob los ntawm cov mob chua leeg no.

Nyob rau hauv cov xwm txheej dab tsi koj tuaj yeem noj finlepsin 400 retard tsuas yog tom qab sab laj tus kws kho mob?

Hauv qab no yog qhia thaum koj tuaj yeem noj finlepsin 400 retard tsuas yog nyob rau qee qhov xwm txheej thiab tsuas yog nrog kev saib xyuas zoo. Thov sab laj nrog koj tus kws kho mob txog qhov no. Qhov no kuj siv rau cov xwm txheej uas cov lus tau hais tseg dhau los nrog koj.

Finlepsin 400 retard yuav tsum tsis txhob siv ib txhij nrog MAO inhibitors. Txoj kev kho nrog MAO inhibitors nres tsis pub dhau 14 hnub ua ntej pib kev kho mob nrog finlepsin 400 retards.

Tsuas yog tom qab ua tib zoo sib piv ntawm cov kev pheej hmoo ntawm kev kho mob thiab cov txiaj ntsig zoo tsim nyog, nrog rau kev saib xyuas ntawm kev ceev faj, finlepsin 400 retard tuaj yeem siv rau cov kab mob ntawm cov ntshav ntawm cov kabmob (hematological kab mob), ua txhaum loj heev rau lub siab, mob siab thiab lub raum (saib "Phiv rau sab" thiab "Dosage" ), tsis ua haujlwm sodium metabolism.

Siv thaum cev xeeb tub thiab lactation

Thaum cev xeeb tub, finlepsin 400 retard yog siv tsuas yog tom qab ua tib zoo sib piv ntawm kev pheej hmoo ntawm kev kho thiab qhov kev cia siab muaj txiaj ntsig los ntawm cov kws kho mob tau koom nrog.

Yog tias muaj mob lossis nyuam qhuav pib cev xeeb tub, tshwj xeeb tshaj yog hnub 20 thiab 40 hnub ntawm cev xeeb tub, finlepsin 400 retard yog qhov tau txais qis tshaj plaws tswj kev qaug dab peg. Qhov tshuaj txhua hnub, tshwj xeeb tshaj yog nyob rau lub sijhawm muaj sib txawv txav ntawm cev xeeb tub, tau muab faib ua ntau qhov me me noj thaum nruab hnub. Nws raug nquahu kom tswj qib ntawm cov khoom muaj sia hauv cov ntshav cov ntshav.

Muaj qee zaus, muaj kev sib txuas nrog kev siv cov tshuaj carbamazepine, kev qhia tsis zoo ntawm cov me nyuam hauv plab, tau hais txog kev sib cais ntawm tus txha caj qaum.

Yog tias ua tau, koj yuav tsum zam kev sib txuas ntawm finlepsin 400 retards nrog lwm cov tshuaj antiepileptic lossis lwm yam tshuaj, vim tias qhov no yuav ua rau muaj kev pheej hmoo ntawm cov me nyuam hauv plab tsis zoo.

Hauv kev sib txuas nrog cov enzyme-ntxias cov yam ntxwv ntawm carbamazepine, nws yuav pom zoo kom muab tshuaj folic acid ua ntej thiab thaum cev xeeb tub.

Txhawm rau kom zam kev mob hemorrhagic hauv tus menyuam mos, kev tswj hwm kev noj qab haus huv ntawm cov tshuaj vitamin K raug pom zoo rau leej niam hauv lub lim tiam dhau los ntawm kev xeeb tub lossis rau tus menyuam yug tom qab yug menyuam tas. Yog tias koj xav tau menyuam, nco ntsoov nrog koj tus kws kho mob tham.

Finlepsin 400 ncua ntev mus rau leej niam cov kua mis, tab sis hauv cov khoom me me uas thaum siv tshuaj kho mob, feem ntau, nws tsis txaus ntshai rau tus menyuam.Tsuas yog tias lub cev tsis zoo ntxiv lossis nce ntxiv ntawm kev tsaug zog (ua kom tsaug zog) hauv tus menyuam, kev pub mis rau menyuam noj raug tso tseg.

Kev siv cov tshuaj ntawm cov menyuam yaus thiab cov neeg laus laus

Vim lub siab cov ntsiab lus ntawm cov tshuaj nquag thiab tsis muaj kev paub nrog kev siv cov ntsiav tshuaj, retard finlepsin 400 retard yuav tsum tsis txhob raug rau cov menyuam yaus hnub nyoog qis dua 6 xyoo.

Rau cov neeg mob laus, finlepsin 400 retard yog tau qhia hauv koob tshuaj tsawg dua.

Noj ntau dhau

Yuam kev ntawm kev siv cov tshuaj thiab overdose

Dab tsi koj yuav tsum xav txog yog tias koj xav cuam tshuam lossis ntxov ntxov tso tseg kev kho mob

Yuav ua li cas yog tias finlepsin 400 retard tau coj los hauv ntau qhov ntau

Cia rau cov neeg mob:

Lub txee lub neej ntawm cov tshuaj yog 3 xyoos.
Lub txee lub neej ntawm cov ntsiav tshuaj retard yog qhia rau ntawm cov ntawv ci ntawm lub ntsej muag blister ntim thiab rau ntawm lub thawv ntawv thawv.
Tom qab lub sijhawm tau teev tseg, tsis txhob siv ntau dua cov ntsiav tshuaj rov qab ntawm pob ntawv no.

Tshuaj muab tshuaj cia kom ncav tsis cuag cov menyuam!

Cov tshuaj no yog muab cia rau hauv ib qho kev mob ib txwm.

Kev Sau thiab daim ntawv ntawm kev tso tawm

Cov tshuaj ntsiav ntev ntev muaj xws li 400 mg carbamazepine. Raws li qhov kev piav qhia, lwm cov khoom siv kuj tseem muaj:

Talcum hmoov
Crospovidone
MCC
Triacetin
Si dioxide tawg faib
Methacrylate copolymer
Stearic Acid Mg.

Cov tshuaj txhuam kheej kheej ntawm cov xim dawb lossis daj daj yog muab tso rau hauv lub hlwv ntawm 10 pcs., Sab hauv pob muaj 5 tus hlwv.

Kho thaj chaw

Ib qho tshuaj anticonvulsant, cov tshuaj tiv thaiv uas muaj txiaj ntsig ntawm cov khoom no yog tricyclic iminostilbene. Ntxiv rau cov nyhuv antiepileptic, psychotropic zoo li tshaj tawm cov haujlwm neurotropic tau pom zoo.Qhov tshwm sim ntawm kev kho mob ua rau cuam tshuam nrog kev cuam tshuam ntawm cov txheej txheem ntawm kev sib kis ntawm kev zam ntawm synapses, yog li txo qhov kis ntawm qaug dab peg. Thaum noj cov tshuaj carbamazepine ntau heev, muaj qhov kev poob qis hauv kev ua tiav tom qab muaj kev npau taws. Cov tshuaj pab txhawm rau txo qis qhov mob ntawm qhov mob nrog trigeminal neuralgia, cov nyhuv no yog vim muaj qeeb qeeb hauv kev xa xov ntawm lub zog xa ncaj qha ncaj qha sab hauv tus txha caj qaum, uas nyob hauv trigeminal hlab ntsha.

Txij li thaum cov tshuaj muaj hypothalamic ntxim rau cov osmoreceptors lawv tus kheej, ib cov tshuaj tiv thaiv kab mob raug kaw rau hauv ntshav qab zib insipidus.

Tom qab noj cov tshuaj, cov tshuaj ua kom nquag plias yuav nqus tau qeeb thiab yuav luag txhua yam. Qhov siab tshaj plaws ntshav ntshav ntawm carbamazepine yog kaw tom qab 4-6 teev. Nws yog tsim nyog sau cia tias cov ntshav theem ntawm carbamazepine tsis linearly nyob ntawm qhov ntau npaum ntawm cov tshuaj, nyob rau hauv cov ntaub ntawv ntau dua, thiab lub plasma concentration nkhaus nws tus kheej muaj daim ntawv hauv toj siab.

Kev noj tshuaj ua rau muaj kev ua haujlwm ntev, nws muaj peev xwm ua tiav theem ntshav me me ntawm carbamazepine piv nrog kev siv cov ntsiav tshuaj zoo. Feem ntau, kev ua kom muaj zog sib luag tshwm sim tom qab 2-8 hnub.

Qhov ntsuas qhov khi ntawm cov ntshav plasma protein yuav raug kaw nyob ntawm qib 70-80%. Cov khoom sib xyaw ua haujlwm nkag mus rau hauv qhov chaw tiv thaiv hniav dawb, hla mus rau hauv niam mis.

Tom qab siv tag nrho ntawm cov tshuaj, ib nrab-lub neej yog tsis ntau tshaj 36 teev. Thaum lub caij nyoog kho mob, qhov ntsuas no tuaj yeem txo los ntawm ib nrab, qhov no feem ntau yog vim qhov induction ntawm microsomal hepatic enzymes.

Tom qab siv ib cov tshuaj, kwv yees li 72% ntawm cov tshuaj uas tau lees txais yog raug tawm los ntawm lub raum (hauv daim ntawv ntawm cov tshuaj metabolites), cov khoom seem nrog cov quav, cov nyiaj me me hauv nws thawj daim ntawv.

Cov lus qhia rau kev siv

Nqe: los ntawm 174 txog 350 rubles.

Cov tshuaj yog noj ntawm qhov ncauj, cov tshuaj yuav xav tau kom huv nrog ib cov dej txaus. Rau qhov yooj yim, lub ncoo kuj tuaj yeem yaj hauv dej, thiab tom qab ntawd haus cov dej uas yuav ua tau. Nws yog tshuaj nyob rau hauv qhov ntau npaum li cas txhua hnub ntawm 400-1200 mg, muab faib ua 1-2 daim ntawv thov ib hnub.

Nws yuav tsum raug sau tseg tias qhov kev siv tshuaj ntau tshaj plaws hauv ib hnub yuav tsum tsis ntau tshaj 1.6 g.

Tshuaj qaug dab peg

Kev kho kom zoo nkauj yog ib txwm pom zoo. Ua ntej, lawv tau raug txiav txim siab kom haus dej qis ntawm cov tshuaj, yav tom ntej lawv tau nce mus txog rau lub sijhawm thaum muaj kev kho mob siab tshaj plaws tau tshwm sim. Yog tias Finlepsin tau raug tshaj tawm ntxiv rau txoj kev kho mob nrog tshuaj tiv thaiv kab mob, qhov koob tshuaj tau nce qeeb qeeb, koj yuav tau kho qhov tshuaj ntau dua lwm cov tshuaj.

Yog tias koj tsis nco qab noj ntxiv, noj tshuaj kom sai li sai tau, raws li koj nco qab. Tsis txhob haus ib khob ob zaug ntawm cov tshuaj.

Cov neeg muaj hnub nyoog tau sau tseg rau haus 200-400 mg rau ib hnub, ua kom ntau npaum li maj mam noj kom txog rau thaum cov hauj lwm zoo tshaj plaws. Thaum kho txoj kev kho, 800 mg yog tshuaj - 1.2 g ntawm cov tshuaj ib hnub, qhov ntau zaus ntawm kev pub nkag ib hnub yog 1-2 p.

Rau cov menyuam muaj hnub nyoog 6-15 xyoo, qhov pib txhaj thawj hnub yog 200 mg, nws qhov nce yog nqa los ntawm 100 mg rau ib hnub. Nrog kev saib xyuas kev kho mob, cov menyuam muaj hnub nyoog 6-10 xyoo raug pom zoo kom noj 400-600 mg ntawm cov tshuaj, cov menyuam ntawm cov laus hnub nyoog (11-15 xyoo) tau raug tso cai 600 mg - 1 g ntawm cov tshuaj.

Lub sijhawm ntawm kev kho tus mob antiepileptic yog txiav txim siab ntawm tus kheej thiab nyob ntawm qhov mob ntawm tus neeg mob thiab qhov tshwm sim ntawm kev kho. Txo cov tshuaj ntau npaum li cas lossis kev ua tiav tiav ntawm kev kho yog ua tau tom qab 2-3 xyoo ntawm qhov tsis muaj mob vwm.

Kev kho yog ua tiav los ntawm kev maj mam txo qhov ntau npaum li cas ntawm cov tshuaj rau 1-2 xyoos, thiab EEG tswj hwm yog tsim nyog. Hauv cov menyuam yaus, thaum txo qis qhov ntau npaum ntawm cov tshuaj, nws yuav tsim nyog coj mus rau hauv qhov kev hloov pauv hauv qhov hnyav nrog lub hnub nyoog.

Idiopathic glossopharyngeal, trigeminal neuralgia

Pib, nws pom tias haus ib koob 200-400 mg ib hnub, qhov ntau zaus siv yog 2 r. Kev nce ntxiv ntawm cov tshuaj yog nqa tawm ua ntej daws qhov mob, feem ntau yog 400-800 mg ntawm cov tshuaj. Hauv cov hauv qab no, feem ntau cov neeg mob tau qhia kom haus dej haus 400 mg ntawm Finlepsin.

Cov neeg laus, nrog rau cov neeg uas muaj kev cuam tshuam ntau dhau rau cov kev ua ub ua no, pom tias haus tsawg kawg 200 mg ntawm cov tshuaj ib hnub ib zaug.

Kev mob siab rau mob ntshav qab zib nrog mob neuropathy

Nws raug nquahu kom haus 600 mg ib hnub twg (noj 1/3 ntawm qhov tshuaj txhua hnub thaum sawv ntxov, so thaum yav tsaus ntuj). Nws tsis tshua pom zoo kom koj noj 600 mg ob zaug ib hnub.

Kev kho mob rau kev tshem tawm cawv (tus neeg mob pw hauv tsev kho mob)

Thoob plaws hnub, nws tau pom tias yuav noj 600 ml ntawm tshuaj, qhov ntau zaus ntawm kev tswj hwm yog 2 r. Hauv cov mob hnyav, nws muaj peev xwm nce qhov ntau dua rau 1.2 g, qhov ntau zaus ntawm kev siv tshuaj yog tib yam.

Kev siv ib txhij siv rau lwm cov tshuaj uas siv los tshem tawm qhov pom ntawm kev haus dej haus cawv, tshwj tsis yog cov tshuaj uas muaj sedative thiab hypnotic nyhuv, tsis yog kav.

Lub sijhawm ntawm txoj kev kho, nws yuav tsum tau soj ntsuam cov plasma qhov taw qhia ntawm carbamazepine.

Txij li thaum qhov tshwm sim ntawm cov kev qhia tsis zoo los ntawm lub hauv nruab nrab ntawm cov hlab ntsha hauv lub cev thiab siv lub zog NS ua tau, ua tib zoo saib xyuas tus neeg mob kom tsim nyog.

Epileptiform dua mob tiv thaiv keeb kwm yav dhau los ntawm kev muaj mob ntau yam sclerosis

Qhov nruab nrab, 200-400 mg yog cov tshuaj, noj tshuaj yog noj ob zaug ib hnub. Lub sijhawm kho nrog Finlepsin yog txiav txim siab ib tus zuj zus.

Kev xav hlwb (kev kho mob thiab kev tiv thaiv)

Qhov pib, ntxiv rau kev tswj hwm qhov tsuas tshuaj yog feem ntau 200-400 mg. Yog tias tsim nyog, koj yuav tsum nce ntxiv rau 400 mg.

Cev xeeb tub, HB

Thaum cev xeeb tub thiab lactation, noj cov tshuaj yog ua tau yog tias qhov nyiaj tau los ntawm cov txiaj ntsig muaj peev xwm dhau qhov txaus ntshai.

Yog tias xav tau siv tshuaj rau hauv lub cev sijhawm 20-40 hnub. sau ntawv noj tshuaj kom tsawg ntawm cov tshuaj noj kom tsawg. Nws yog qhov zoo dua rau txhawm rau qhov tshuaj txhua hnub rau hauv ob peb koob tshuaj uas tau noj thaum nruab hnub. Qhov no yuav xav tau tswj hwm lub plasma concentration ntawm Finlepsin.

Kuj tsis tshua muaj tshwm sim, hauv cov menyuam yaus uas lawv niam tau kho nrog tshuaj, kev qhia tsis meej tau kuaj pom, hauv qee kis muaj cais ntawm tus txha nraub qaum.

Txhawm rau tiv thaiv qhov tshwm sim ntawm hemorrhagic tshwm sim hauv cov menyuam mos, nws yuav tsum tau ntxiv kev saib xyuas rau leej niam cov kev npaj raws li ntawm vit. K, nws tseem tuaj yeem nqa tawm kev kho mob no hauv cov menyuam mos.

Finlepsin kis mus rau niam mis, tab sis hauv kev txhaj tsawg, yog li ntawd nws tsis tuaj yeem muaj qhov tsis zoo rau tus menyuam lub cev. Yog tias tus menyuam mos tau poob ceeb thawj, ua tsis tsaug zog heev, sau cia yuav tsum pub niam mis.

Cov Kev Tsis Txaus Ntseeg thiab Kev Ceev Faj

Koj yuav tsum tsis txhob noj carbamazepine nrog:

Kev kuaj pom tus mob pob txha
Mob Nruab Nrab Kev Kuaj Mob
Ua rau muaj kev cuam tshuam ntau ntxiv rau cov tshuaj nquag, rau cov neeg sawv cev nthuav tawm cov tshuaj tiv thaiv kab mob siab
Lub manifestation ntawm sib quas ntus porphyria.

Muab qhov tseeb tias tshuaj muaj peev xwm ua rau muaj ntau yam tshwj xeeb ntawm qaug dab peg, hauv qhov no, nws lub hom phiaj yog contraindicated rau cov neeg uas tau txheeb xyuas cov mob no qaug dab peg.

Cov tshuaj yuav tau siv nrog ceev faj thaum muaj teeb meem tsis txaus sodium metabolism, ib tug xov tooj ntawm cov kab mob ntawm cov ntshav ua rau cov plab hnyuv siab raum, kev ua haujlwm tsis zoo ntawm CVS, lub raum thiab lub siab.

Hla kev sib txuam yeeb tshuaj

Txais tos nrog cov tshuaj tiv thaiv ntawm ib qho tshwj xeeb CYP3A4 isoenzyme tuaj yeem ua rau muaj qhov nce ntxiv ntawm plasma theem ntawm carbamazepine, nrog rau qhov tshwm sim ntawm cov tsos mob tsis zoo.

Kev siv cov inducers ntawm CYP3A4 isoenzyme muaj peev xwm ua kom nrawm cov teeb meem hloov pauv ntawm cov khoom tseem ceeb ntawm Finlepsin thiab txo nws cov ntshav plasma concentration, ua raws li qhov txo qis ntawm qhov mob ntawm cov nyhuv kho kom tsawg. Thiab vim yog lawv qhov tshem tawm txoj haujlwm, qhov kev txo qis ntawm biotransformation ntawm carbamazepine nws tus kheej thiab nce rau hauv lub plasma index tuaj yeem raug sau cia.

Felbamate tuaj yeem txo qis ntshav ntshav carbamazepine, thaum nce tus nqi ntawm nws cov metabolites thiab txo qis ntshav ntawm felbamate.

Kev nqus ntawm isotretinoin cuam tshuam txog kev noj qab haus huv ntawm bioavailability, nrog rau kev tshem tawm ntawm cov tshuaj nquag Finlepsin, yog li koj yuav tsum tswj lub plasma qhov taw qhia ntawm carbamazepine.

Carbamazepine ntshav theem yog nce los ntawm lub simultaneous siv macrolides, azoles, protease inhibitors, loratadine, Isoniazid, terfenadine, fluoxetine, danazol, nicotinamide, diltiazem, dextropropoxyphene, cimetidine, txiv kab ntxwv qaub kua txiv, propoxyphene, felodipine, verapamil, viloksazina, fluvoxamine, acetazolamide, desipramine.

Primidone nrog valproic acid tuaj yeem txav lub ntsiab lus tseem ceeb ntawm Finlepsin los ntawm kev sib txuas nrog cov plasma protein, thaum lub siab ntawm kev ua kom muaj cov metabolites nce. Thaum noj cov tshuaj valproic acid, kev tsis meej pem tuaj yeem pom, tus neeg mob yuav poob mus rau hauv coma.

Thaum lub sijhawm kev siv Finlepsin, kev txo qis ntawm cov ntshav plasma concentration ntawm cov tshuaj muaj peev xwm ua tau:

GKS
Digoxin
Clobazam
Valproic Acid
Primidon
Tetracyclines
Alprazolam
Oxcarbazepine
Ethosuximide
Cyclosporin
Estrogen-progestogen tshuaj
Tshuaj txiav yeeb
Theophylline
Haloperidol
Risperidone
Anticoagulants uas tau noj ntawm qhov ncauj
Cov calcium calcium blockers
Trimadol
Lamotrigine
Tricyclic cov tshuaj tiv thaiv kev ntxhov siab
Felbamate
Tiag Tiag
Topiramat
Tramadol
Protease inhibitors
Olanzapine
Intraconazole
Midazolam
Clozapine
Levothyroxine
Ziprasidone
Praziquantel.

Kev txo qis ntshav plasma carbamazepine yog pom nrog kev siv cisplatin, primidone, doxorubicin, phenobarbital, metsuximide, theophylline, phenytoin, rifampicin, fensuximide. Clonazepam, kev npaj raws li St. John lub wort, valproic acid, valpromide, oxcarbazepine, tuaj yeem ua rau tib cov txiaj ntsig.

Kuj tsis tshua muaj, qhov kev txo qis hauv plasma theem ntawm phenytoin yog sau tawm tsam ntawm keeb kwm ntawm kev kho carbamazepine, nrog rau kev nce mefenitoin.

Txhais tau los ntawm pab pawg tetracycline muaj peev xwm txo qis kev kho mob ntawm kev siv carbamazepine.

Finlepsin txo qhov kev ua kom tsis taus ntawm cov tshuaj uas muaj ethanol.

Thaum noj cov tshuaj Li, nws muaj peev xwm txhim kho cov kev mob hlwb ntawm txhua cov tshuaj.

Cov tshuaj cuam tshuam ntau dua qhov ua rau hepatotoxic siv ntawm isoniazid.

Kev siv cov tshuaj tua kab mob paracetamol tuaj yeem nce qhov muaj feem ua rau muaj kev phom sij rau lub siab ua haujlwm thiab txo qis kev kho mob ntawm cov tshuaj los ntawm kev ua kom lub cev hloov pauv sai.

Cov tshuaj tuaj yeem ua kom lub zog pauv hloov pauv hauv cov tshuaj rau kev tswj hwm hauv tshuaj loog, qhov kev pheej hmoo ntawm hepatotoxic cuam tshuam nce.

Muaj qhov ua rau lub zog poob siab rau lub hauv nruab nrab lub paj hlwb, nrog rau txo qis cov nyhuv anticonvulsant ntawm carbamazepine thaum kho nrog phenothiazine, clozapine, molindone, antidepressants los ntawm tricyclic pawg, maprotiline, thiab haloperidol.

Cov tshuaj Myelotoxic ntau ntxiv rau hematotoxicity ntawm carbamazepine.

Noj tshuaj kho mob tuaj yeem tuaj yeem ua rau lub cev poob siab.

Cov tshuaj yuav ua rau muaj kev tua cov thyroid hormones ntau ntxiv.

Finlepsin nrawm rau kev hloov pauv ntawm cov zaub mov ntawm praziquantel, anticoagulants tsis ncaj, COCs, thiab folic acid-based cov khoom lag luam.

Nws yog tsim nyog sau cia tias Finlepsin ua kom tsis muaj zog ntawm cov nyhuv tsis ua rau cov leeg ua kom lub cev tsis ua haujlwm.

MAO inhibitors nce ntxiv ntawm kev muaj peev xwm ua rau mob hyperthermic zoo li muaj kev kub siab txog kev nyuaj siab, mob huam, mob tsawg, qee qhov kev ua kom neeg tuag taus yog ua tau.

Tus neeg sawv cev rau kev kho mob sib kis mob nce ceev ntawm kev tsim cov tshuaj nephrotoxic metabolites ntawm cov tshuaj xws li methoxyflurane.

Phiv thiab haus tshaj

Feem ntau, cov tsos mob ntawm qhov tsis zoo yog cuam tshuam nrog kev tswj hwm kev noj tshuaj ntau dhau, nrog rau kev hloov pauv ntshav hauv cov ntshav ntawm cov tshuaj nquag Finlepsin. Feem ntau, cov teeb meem tsis haum ntawm NS tau sau tseg: ataxia, qaug zog, nkees heev, ua rau pom kev mob taub hau. Qhov tshwm sim ntawm kev ua xua tsis raug tswj hwm tawm pob (tawm pob ntawm hom urticaria, erythroderma). Ntawm ib feem ntawm cov kab mob hematopoietic, kuj tseem yuav muaj kev ua txhaum:

Lymphadenopathy
Kev ua kom paub eosinophilia
Kev tsim kho leukocytosis lossis mob leukopenia
Cov tsos mob ntawm thrombocytopenia.

Lub plab zom mov tuaj yeem teb nrog kev tawm tsam ntawm xeev ntuav, nquag ntuav ntuav, lub qhov ncauj qhuav, thiab nce qib hauv daim siab enzymes. Tej zaum yuav muaj mob raws plab lossis quav tawv.

Kev tuav kua dej, qhov hloov pauv ntawm lub cev, qhov xwm yeem, thiab mob hyponatremia kuj tseem yuav tau sau tseg. Kev ua txhaum kev ua txhaum los ntawm CCC (mob angina tawm tsam), cov plab hnyuv siab raum, kab mob genitourinary, nrog rau cov leeg ua haujlwm.

Tom qab noj tshuaj ntau dhau, cov tsos mob tuaj yeem pom tias ua txhaum cai ntawm kev ua haujlwm ntawm CVS, cov khoom hauv lub cev thiab lub siab ntsws. Kev txiav txim siab ntawm qhov pom ntawm qhov pom, inhibition ntawm lub hauv nruab nrab lub paj hlwb, lub ntsws txhaws, kev mob tshwm sim ntawm bradycardia, ntshav nce siab, qhov tshwm sim ntawm pom kev tsis meej, kev ntxhov siab ntau dhau, qhov tso zis tsis zoo, nquag tuaj ntawm xeev siab thiab ntuav raug kaw.

Kev kho mob thaum kws kho mob yog kws kho, qee kis ces yuav tsum tau pw hauv tsev kho mob.

Carbamazepine

ALSI Pharma, Russia

Nqi los ntawm 50 txog 196 rubles.

Cov tshuaj yog cim los ntawm cov tshuaj tiv thaiv anticonvulsant. Nws yog siv rau kev qaug dab peg, lub cev ntawm kev mob ntshav qab zib neuropathy, haus dej cawv tawm, manic tej yam kev mob. Cov tshuaj nquag ua haujlwm yog tib yam li hauv Finlepsin, yog li cov txheej txheem ntawm kev ua ntawm cov tshuaj yog tib yam. Muaj nyob hauv ntsiav tshuaj daim ntawv.

Pros:

Tshem Tawm Kev ntxhov siab vim
Txhawb Kev Sib Txuas Lus ntawm Neeg Mob
Siv rau Kluver-Bucy syndrome.

Cons:

Tsis qhia rau qhov thaiv atrioventricular
Tej zaum yuav cem cov lus pov thawj
Cov kev ceev faj tau muab rau cov prostatic hyperplasia.

Yuav siv li cas: noj ntau thiab hom tshuaj kho

Sab hauv, tsis hais txog ntawm pluas mov nrog me me ntawm cov kua.

Retard ntsiav tshuaj (ib ntsiav tshuaj tag nrho lossis ib nrab) yuav tsum nqos tag nrho, tsis tas yuav zom, nrog ib qho kua tsawg tsawg, 2 zaug hauv ib hnub. Hauv qee tus neeg mob, thaum siv cov ntsiav tshuaj retard, nws yuav tsim nyog los nce qhov tshuaj ntawm cov tshuaj.

Tshuaj qaug dab peg Nyob rau hauv rooj plaub uas qhov no ua tau, carbamazepine yuav tsum yog kws kho mob tshuaj tua kab mob. Kev kho mob pib nrog kev siv tshuaj rau ib qho me me txhua hnub, uas tom qab ntawd maj mam nce ntxiv kom txog thaum pom qhov txiaj ntsig zoo tshaj plaws.

Qhov sib ntxiv ntawm Finlepsin retard rau kev kho cov tshuaj tiv thaiv kev ua haujlwm tsis tu ncua yuav tsum tau nqa tawm maj, thaum cov koob tshuaj ntawm cov tshuaj siv tsis hloov lossis, yog tias tsim nyog, tau kho.

Rau cov laus, cov koob tshuaj thawj zaug yog 100-200 mg 1-2 zaug ib hnub. Tom qab ntawd qhov koob tshuaj yog maj mam nce ntxiv kom txog rau qhov ua kom tau txiaj ntsig zoo tshaj plaws (feem ntau 400 mg 2-3 zaug hauv ib hnub, ntau tshaj 1.6-2 g / hnub).

Cov menyuam yaus txij thaum 4 xyoo - hauv koob pib 20-60 mg / hnub, maj mam nce ntxiv los ntawm 20-60 mg txhua lwm hnub. Hauv cov menyuam muaj hnub nyoog laus dua 4 xyoos - hauv thawj koob 100 mg / hnub, qhov tshuaj ntau dua tau nce zuj zus, txhua lub lim tiam los ntawm 100 mg. Txhawb cov koob tshuaj: 10-20 mg / kg ib hnub (hauv ntau ntau zaug): rau 4-5 xyoos - 200-400 mg (hauv 1-2 koob), 6-10 xyoo - 400-600 mg (hauv 2-3 koob ), rau 11-15 xyoo - 600-1000 mg (hauv 2-3 koob).

Nrog trigeminal neuralgia, 200-400 mg / hnub yog kho nyob rau thawj hnub, maj mam nce los ntawm tsis ntau tshaj 200 mg / hnub kom txog rau thaum qhov mob tsis ua haujlwm (qhov nruab nrab 400-800 mg / hnub), thiab tom qab ntawd txo rau qhov kev siv tshuaj tsawg kawg. Yog tias muaj mob neurogenic keeb kwm, qhov pib noj yog 100 mg 2 zaug ib hnub ntawm thawj hnub, tom qab ntawd cov koob tshuaj tau nce tsis ntau tshaj 200 mg / hnub, yog tias tsim nyog, nce nws los ntawm 100 mg txhua 12 teev kom txog thaum qhov mob hnov mob. Cov koob tshuaj txij nkawm yog 200-1200 mg / hnub hauv ntau qhov tshuaj.

Hauv kev kho cov neeg laus thiab cov neeg mob lub siab tsis zoo, qhov pib koob tshuaj yog 100 mg 2 zaug ib hnub.

Cawv tshem tawm tus mob syndrome: nruab nrab koob - 200 mg 3 zaug ib hnub, hauv cov kis loj, thaum thawj ob peb hnub, qhov tshuaj yuav nce ntxiv rau 400 mg 3 zaug ib hnub. Thaum pib ntawm kev kho mob rau cov tsos mob hnyav tshem tawm, nws raug nquahu kom muab tshuaj nrog cov tshuaj sedative-hypnotic (clomethiazole, chlordiazepoxide).

Ntshav qab zib insipidus: qhov nruab nrab koob rau cov neeg laus yog 200 mg 2-3 zaug ib hnub. Hauv cov menyuam yaus, lub koob tshuaj yuav tsum raug txo kom nruj raws li lub hnub nyoog thiab lub cev qhov hnyav ntawm cov menyuam.

Mob ntshav qab zib neuropathy, nrog rau mob: qhov nruab nrab koob yog 200 mg 2-4 zaug ib hnub.

Hauv kev tiv thaiv mob rov huam tuaj ntawm kev xav thiab schizoaffective psychoses - 600 mg / hnub hauv 3-4 koob.

Hauv kev mob hnyav thiab qhov tsis haum (bipolar) cuam tshuam, kev txhaj tshuaj txhua hnub yog 400-1600 mg. Qhov nruab nrab txhua hnub koob tshuaj yog 400-600 mg (hauv 2-3 koob). Hauv lub xeev kev mob siab heev, qhov koob tshuaj tau nce nrawm dua, nrog kev kho kom zoo los ntawm kev cuam tshuam los ntawm kev cuam tshuam - maj mam (kom txhim kho qhov ua siab ntev).

Pharmacological kev txiav txim

Lub tshuab ntawm kev ua yog txuam nrog qhov thaiv ntawm voltage-gated Na + channels, uas ua kom muaj kev ruaj khov ntawm cov neuron membrane, inhibition ntawm cov tsos ntawm cov feem ntawm kev puas tsuaj ntawm neurons thiab txo qis ntawm kev sib txuas ntawm lub zog. Tiv thaiv qhov rov tsim ntawm Na + -cov kev txiav txim siab lub peev xwm hauv depolarized neurons. Txo kev tso tawm ntawm qhov txaus siab neurotransmitter amino acid glutamate, nce qhov txo qhov qaug dab peg tsawg, thiab lwm yam. txo txoj kev pheej hmoo ntawm kev tsim muaj mob chwv leeg. Nws tsub kom qhov conductivity rau K +, modulates voltage-gated Ca2 + channels, uas tseem tuaj yeem ua rau cov nyhuv anticonvulsant ntawm cov tshuaj.

Kho cov kev puas ntsoog tus kab mob hloov pauv thiab thaum kawg ua rau muaj kev cia siab rau cov neeg mob, pab txhawb lawv cov kev tsim kho kom rov qab zoo li qub. Nws tuaj yeem raug suav tias yog cov tshuaj kho mob tseem ceeb thiab hauv kev sib xyaw nrog lwm cov tshuaj anticonvulsant.

Nws yog qhov zoo rau focal (ib nrab) qaug dab peg (yooj yim thiab txoj), nrog los yog tsis nrog los ntawm kev muaj feem thib ob, rau kev kho tus mob feem ntau tonic-clonic mob chua leeg, nrog rau kev sib xyaw ntawm cov hom no (feem ntau tsis muaj txiaj ntsig rau me me qaug dab peg - tso quav mal, tsis tuaj thiab myoclonic qaug dab peg) Cov.

Cov neeg mob qaug dab peg (tshwj xeeb tshaj yog nyob rau cov menyuam yaus thiab cov hluas) muaj cov txiaj ntsig zoo ntawm cov tsos mob ntawm kev ntxhov siab thiab kev nyuaj siab, nrog rau kev txo qis kev txob taus thiab kev txhoj puab heev. Qhov kev cuam tshuam ntawm kev txawj ntse ntawm lub hlwb kev ua haujlwm thiab psychomotor kev ua tau zoo yog qhov koob tshuaj thiab muaj kev hloov siab.

Qhov pib ntawm cov nyhuv anticonvulsant sib txawv los ntawm ob peb teev mus rau ntau hnub (qee lub sijhawm txog li 1 hlis vim kev pib-pib ntawm cov metabolism).

Nrog rau qhov tseem ceeb thiab theem siab trigeminal neuralgia feem ntau nws txwv tsis pub muaj qhov tsos ntawm qhov mob tawm tsam. Ua tau zoo rau kev daws mob ntawm neurogenic mob nyob rau hauv lub dryness ntawm tus txha nqaj qaum, mob nraub qaum tom qab mob caj dab thiab postherpetic neuralgia.Kev daws qhov mob nyob rau hauv trigeminal neuralgia tau sau tseg tom qab 8-72 teev.

Yog hais tias haus dej haus cawv haus cawv, nws nce qhov pib ua rau qhov tsim nyog (uas feem ntau txo qis hauv tus mob no) thiab txo qhov mob tsis zoo ntawm cov chaw kuaj mob tshwm sim ntawm tus mob (nce excitability, tshee, gait tsis meej).

Hauv cov neeg mob uas muaj ntshav qab zib insipidus ua rau sai sai them nyiaj ntawm cov dej tshuav, txo cov diuresis thiab nqhis dej.

Antipsychotic (antimaniacal) kev ua tom qab 7-10 hnub, tuaj yeem yog vim yog inhibition ntawm cov metabolism hauv dopamine thiab norepinephrine.

Daim ntawv noj tshuaj ntau dua ua rau muaj kev saib xyuas ntawm lub zog ruaj khov dua ntawm cov carbamazepine hauv cov ntshav tsis muaj "peaks" thiab "dips", uas tso cai rau txo qhov zaus thiab qhov mob ntawm cov teeb meem tsis zoo ntawm kev kho, kom nce cov txiaj ntsig ntawm kev kho mob txawm tias siv cov koob tshuaj uas tsis tshua muaj. Dr. qhov txiaj ntsig tseem ceeb ntawm daim ntawv ntev ntev yog qhov ua tau ntawm kev noj 1-2 zaug ib hnub.

Cov lus qhia tshwj xeeb

Kev kho kab mob vwm pib ntawm kev teem caij txhaj tshuaj me me, ib tus zuj zus rau lawv kom ua tiav cov txiaj ntsig kho yam xav tau.

Nws raug nquahu los txiav txim siab qhov siab nyob hauv ntshav txhawm rau txhawm rau xaiv cov koob tshuaj kom zoo tshaj plaws, tshwj xeeb nrog kev sib txuas ua ke.

Thaum hloov mus rau tus neeg mob mus rau carbamazepine, koob tshuaj ntawm cov tshuaj tiv thaiv kab mob ua ntej yuav tsum maj mam txo kom txog thaum nws tso tseg kiag li.

Qhov kev tso tseg sai sai ntawm kev noj Finlepsin retard tuaj yeem ua rau qaug dab peg. Yog tias nws yuav tsum tau txais kev kho mob sai sai, tus neeg mob yuav tsum tau hloov mus rau lwm cov tshuaj tiv thaiv kab mob hauv qab daim ntawv npog ntawm cov tshuaj qhia hauv cov xwm txheej zoo li no (piv txwv li, diazepam muab tshuaj rau txoj leeg lossis hauv qhov quav, lossis phenytoin muab tshuaj iv).

Muaj ntau tus neeg mob ntuav, raws plab thiab / lossis cov khoom noj tsis txaus, ua kom yuag thiab / lossis kev nyuaj siab ua pa ntawm cov menyuam tshiab uas lawv niam noj carbamazepine sib xyaw nrog lwm cov tshuaj anticonvulsants (cov kev coj ua no yuav yog qhov qhia tias "tshem tawm" cov kabmob ntawm cov menyuam mos).

Ua ntej sau ntawv ntawm Finlepsin retard thiab thaum kho, nws yog qhov yuav tsum tau kawm kab mob siab, tshwj xeeb tshaj yog rau cov neeg mob uas muaj keeb kwm muaj kab mob siab, nrog rau cov neeg laus laus. Yog tias muaj neeg nce siab rau lub siab ua haujlwm lossis thaum lub siab ua haujlwm siab, cov tshuaj yuav tsum tau txiav tawm tam sim ntawd. Ua ntej pib kev kho mob, nws tseem yuav tsum ua qhov kev kawm txog cov ntshav ntshav (suav nrog platelet suav, reticulocyte suav), ntshiab Fe concentration, urinalysis, ntshav urea concentration, EEG, kev txiav txim siab cov ntshav electrolyte concentration (thiab qee zaus thaum kho, vim tias kev tsim kho tau ntawm hyponatremia). Tom qab, cov cim no yuav tsum tau saib xyuas thaum thawj lub hlis ntawm kev kho mob txhua lub lim tiam, thiab tom qab ntawd txhua hli.

Carbamazepine yuav tsum thim tawm sai sai yog tias muaj qhov tsis haum lossis cov tsos mob tshwm sim uas xav tias yog tsim ntawm Stevens-Johnson syndrome lossis Lyell's syndrome. Cov tawv nqaij me me (cais cov macular lossis maculopapular exanthema) feem ntau ploj mus li ob peb hnub lossis ntau lub hlis txawm hais tias muaj kev kho mob txuas ntxiv lossis tom qab txo cov koob tshuaj (tus neeg mob yuav tsum tau saib zoo los ntawm tus kws kho mob nyob rau lub sijhawm no).

Carbamazepine muaj qhov ua haujlwm tsis muaj zog anticholinergic, thaum kev kho mob rau cov neeg mob uas muaj kev mob siab ntxiv, nws txoj kev tshuaj xyuas tas li yog qhov tsim nyog.

Lub sijhawm ntawm kev ua haujlwm ntawm cov neeg mob hlwb tsis txaus ntseeg yuav tsum tau coj mus rau hauv tus lej, thiab hauv cov neeg mob laus, muaj peev xwm tsim kev tsis meej lossis npau taws.

Txog niaj hnub no, muaj cov ntawv tshaj tawm txawv ntawm cov txiv neej tsis muaj peev xwm thiab / los yog cov phev txiv neej tsis txaus (kev sib raug zoo ntawm cov kev tsis taus nrog carbamazepine tseem tsis tau tsim).

Muaj cov ntaub ntawv hais txog kev los ntshav rau cov poj niam thaum coj khaub ncaws hauv rooj plaub uas qhov ncauj tiv thaiv tau siv nyob rau tib lub sijhawm. Carbamazepine tuaj yeem cuam tshuam loj heev rau kev ntseeg tau ntawm cov tshuaj tiv thaiv qhov ncauj, yog li cov poj niam muaj hnub nyoog deev yuav tsum siv lwm txoj hauv kev tiv thaiv kev xeeb tub thaum kho.

Yuav tsum tau siv cov carbamazepine nkaus xwb hauv kev saib xyuas mob.

Nws yog ib qho tsim nyog yuav tsum tau qhia rau cov neeg mob txog cov tsos mob thaum ntxov ntawm kev muaj tshuaj lom neeg hauv kev muaj peev xwm ua rau cov ntshav tsis huv, nrog rau cov tsos mob ntawm daim tawv thiab daim siab. Tus neeg mob tau qhia txog qhov yuav tsum tau mus sab laj nrog tus kws kho mob tam sim ntawd yog tias muaj qhov tsis tsim nyog xws li ua npaws, mob caj pas, tawm pob, txhaws ntawm lub qhov ncauj ntawm qhov ncauj, ua rau mob doog ntshav, mob ntshav hauv daim petechiae lossis purpura.

Feem ntau, qhov ua kom txo qis hauv cov ntshav pliav plooj thiab / lossis cov qe ntshav dawb tsis yog qhov txhawm rau qhov pib ntawm mob ntshav qog lossis agranulocytosis. Txawm li cas los xij, ua ntej pib kev kho mob, nrog rau qee lub sijhawm hauv cov txheej txheem kev kho mob, kev kuaj ntshav hauv cov ntshav yuav tsum tau ua, suav nrog suav cov platelets thiab tejzaum reticulocytes, nrog rau kev txiav txim siab qhov concentration ntawm Fe hauv cov ntshav cov ntshav.

Tsis muaj kev hloov pauv hloov asymptomatic leukopenia tsis xav kom thim tawm, txawm li cas los xij, kev kho mob yuav tsum tsis ua mus ntxiv yog tias muaj mob leukopenia lossis leukopenia tshwm, nrog cov tsos mob ntawm tus kab mob kis.

Ua ntej pib txoj kev kho mob, nws raug nquahu kom ua qhov kev kuaj xyuas ophthalmological, suav nrog kev tshuaj xyuas cov nyiaj pob nrog lub pob hluav taws thiab ntsuas ntawm lub zog intraocular yog tias tsim nyog. Thaum muaj daim ntawv sau tshuaj rau cov neeg mob uas muaj kev mob siab ntawm intraocular, kev soj ntsuam tas li ntawm qhov ntsuas no yuav tsum ua.

Nws raug nquahu kom tso tseg kev siv ethanol.

Cov tshuaj nyob rau hauv daim ntawv ntev ntev tuaj yeem nqa ib zaug, thaum tsaus ntuj. Qhov xav tau nce cov koob tshuaj thaum hloov mus rau ntsiav tshuaj retard yog qhov tsawg kawg.

Txawm hais tias kev sib raug zoo ntawm koob tshuaj carbamazepine, nws qhov kev mob siab thiab kev soj ntsuam lossis kev tso siab yog tsawg heev, txawm li cas los xij, kev txiav txim siab tsis tu ncua ntawm kev txiav txim siab ntawm cov carbamazepine yuav pab tau nyob rau hauv cov xwm txheej hauv qab no: nrog kev nce siab ntau zaus hauv kev tawm tsam, txhawm rau tshuaj xyuas seb tus neeg mob tau noj tshuaj tsis raug cai, thaum lub sijhawm thaum cev xeeb tub, hauv kev kho mob ntawm menyuam yaus lossis tub ntxhais hluas, nrog kev xav tias malabsorption ntawm cov tshuaj, nrog kev xav tias muaj kev txhim kho tshuaj lom yog tias tus neeg mob tau noj maet ob peb tshuaj.

Hauv cov poj niam uas muaj hnub nyoog yug me nyuam, carbamazepine yuav tsum siv cov tshuaj kho mob thaum tsim nyog (siv tshuaj tsawg kawg nkaus) - qhov ntau zaus ntawm kev mob plab yug me nyuam hauv cov menyuam mos yug los rau cov poj niam uas tau ua ke nrog cov tshuaj tiv thaiv kab mob siab dua rau cov neeg uas tau txais txhua yam tshuaj no ua kev kho mob hlwb.

Thaum cev xeeb tub tshwm sim (thaum txiav txim siab txog kev teem caij carbamazepine thaum cev xeeb tub), nws yuav tsum ua tib zoo los sib piv cov txiaj ntsig ntawm kev kho thiab nws qhov teeb meem tshwm sim, tshwj xeeb tshaj yog nyob rau thawj 3 lub hlis thaum cev xeeb tub. Nws raug paub tias cov menyuam yaus yug los ntawm leej niam nrog mob vwm sib kis tau mob siab rau hauv plab kev loj hlob tsis zoo, suav nrog kev ua tsis tiav. Carbamazepine, zoo li tag nrho lwm cov tshuaj tiv thaiv kev mob, tuaj yeem ua rau muaj kev pheej hmoo ntawm cov mob no.Muaj cov ntaub ntawv sib cais los ntawm tus neeg mob ntawm cov kab mob ua tsis taus pa thiab tsis zoo, suav nrog kev tsis kaw cov pob txha caj qaum (spina bifida). Cov neeg mob yuav tsum tau muab cov ntaub ntawv hais txog qhov ua tau los txhawm rau txhawm rau txhawm rau ua kom muaj qhov phom sij thiab muaj peev xwm los soj ntsuam kev kuaj mob ua ntej.

Cov tshuaj antiepileptic nce folic acid deficiency, uas feem ntau pom thaum cev xeeb tub, uas tuaj yeem ua rau muaj qhov tsis zoo ntawm kev yug menyuam hauv menyuam yaus (ua ntej thiab thaum cev xeeb tub, folic acid ntxiv yog pom zoo). Txhawm rau tiv thaiv kev nce ntshav hauv cov menyuam yug tshiab, nws raug nquahu kom cov pojniam nyob hauv lub asthiv kawg ntawm cev xeeb tub, nrog rau cov menyuam yug menyuam tshiab, yuav tsum tau muaj cov tshuaj vitamin K1.

Carbamazepine kis mus rau niam cov kua mis; cov txiaj ntsig thiab qhov tsis xav tau ntawm kev pub niam mis yuav tsum muab piv nrog kev kho mob txuas ntxiv. Cov niam cov niam noj carbamazepine tuaj yeem pub mis rau lawv cov menyuam tau noj, muab tau tias tus menyuam raug soj qab rau kev txhim kho kev pheej hmoo tsis zoo (piv txwv, tsaug zog hnyav, kev tsis haum tshuaj tawv nqaij).

Thaum lub sijhawm kho mob, yuav tsum tau saib xyuas thaum tsav tsheb thiab koom nrog lwm yam kev phom sij uas yuav tsum muaj kev mloog zoo thiab ceev ntawm cov kev tiv thaiv psychomotor.

Cev xeeb tub thiab lactation

Yog tias ua tau, Finlepsin retard yog raug samfwm rau cov pojniam muaj hnub nyoog yug menyuam hauv daim ntawv ntawm kev kho mob, hauv kev siv tshuaj tsawg kawg nkaus, vim tias qhov ntsuas mob tsis xwm yeem ntawm cov me nyuam yug tshiab los ntawm cov niam uas siv cov tshuaj tiv thaiv kev tiv thaiv mob siab dua rau kev kho tus mob.

Thaum cev xeeb tub tshwm sim, nws yog ib qho tsim nyog los sib piv cov txiaj ntsig ntawm kev kho thiab qhov muaj peev xwm ua tau tshwm sim, tshwj xeeb tshaj yog nyob rau thawj peb lub hlis thaum cev xeeb tub.

Nws raug paub tias cov menyuam yaus ntawm leej niam uas muaj kev txom nyem los ntawm kev mob vwm tuaj yog thawj coj rau txoj kev loj hlob ntawm intrauterine, suav nrog kev ua tsis tiav. Finlepsin retard tuaj yeem ua rau muaj kev pheej hmoo ntawm cov teeb meem no. Muaj cov ntaub ntawv sib cais los ntawm tus neeg mob ntawm cov kab mob ua tsis taus pa thiab tsis zoo, suav nrog kev tsis kaw cov pob txha caj qaum (spina bifida). Cov tshuaj antiepileptic nce folic acid deficiency, uas feem ntau pom thaum cev xeeb tub, uas tuaj yeem ua rau muaj qhov tsis zoo ntawm kev yug menyuam hauv menyuam yaus, yog li noj folic acid pom zoo ua ntej npaj lub sijhawm cev xeeb tub thiab thaum cev xeeb tub. Txhawm rau tiv thaiv hemorrhagic muaj teeb meem hauv cov menyuam mos, nws raug pom zoo tias cov poj niam nyob rau lub lim tiam dhau los ntawm cev xeeb tub, nrog rau cov menyuam yug menyuam, yuav tsum tau muaj tshuaj vitamin K.

Carbamazepine hla mus rau niam mis, yog li cov txiaj ntsig thiab qhov tsis xav tau ntawm kev pub niam mis yuav tsum muab piv nrog kev kho mob txuas ntxiv. Nrog kev pub mis niam txuas ntxiv thaum noj cov tshuaj, koj yuav tsum tsim kev soj ntsuam rau tus menyuam hauv kev txuas nrog qhov muaj feem ua rau muaj kev phiv tshuaj (piv txwv, tsaug zog heev, kev tsis haum ntawm daim tawv nqaij).